MCID: INT009
MIFTS: 29

Intracranial Abscess

Categories: Neuronal diseases

Aliases & Classifications for Intracranial Abscess

MalaCards integrated aliases for Intracranial Abscess:

Name: Intracranial Abscess 12 15 73

Classifications:



External Ids:

Disease Ontology 12 DOID:10095
ICD9CM 35 324.0
NCIt 50 C34734
UMLS 73 C0021874

Summaries for Intracranial Abscess

Disease Ontology : 12 A central nervous system disease that is located in the skull and is characterized by a collection of pus (infected material) inside the skull.

MalaCards based summary : Intracranial Abscess is related to dental abscess and ethmoid sinusitis. An important gene associated with Intracranial Abscess is LATS2 (Large Tumor Suppressor Kinase 2). The drug Carbon monoxide has been mentioned in the context of this disorder. Affiliated tissues include the skull, bone and brain, and related phenotypes are cardiovascular system and muscle

Related Diseases for Intracranial Abscess

Diseases related to Intracranial Abscess via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 32)
# Related Disease Score Top Affiliating Genes
1 dental abscess 10.2 BIN1 CRP
2 ethmoid sinusitis 10.1 CRP TWIST1
3 aortic valve disease 1 10.0 CRP TWIST1
4 sinusitis 10.0
5 meningitis 9.8
6 frontal sinusitis 9.7
7 glioma 9.7
8 otitis media 9.6
9 agammaglobulinemia, x-linked 9.6
10 nasopharyngeal carcinoma 9.6
11 melioidosis 9.6
12 malignant glioma 9.6
13 lymphoma 9.6
14 mastoiditis 9.6
15 endocarditis 9.6
16 nasopharyngitis 9.6
17 subdural empyema 9.6
18 suppurative otitis media 9.6
19 graves' disease 9.6
20 acoustic neuroma 9.6
21 typhoid fever 9.6
22 neuroma 9.6
23 cervicitis 9.6
24 agammaglobulinemia 9.6
25 pneumonia 9.6
26 diverticulitis 9.6
27 influenza 9.6
28 vasculitis 9.6
29 haemophilus influenzae 9.6
30 headache 9.6
31 ectopia cordis 9.6
32 gliosarcoma 9.5 MGMT TWIST1

Comorbidity relations with Intracranial Abscess via Phenotypic Disease Network (PDN):


Acute Cystitis

Graphical network of the top 20 diseases related to Intracranial Abscess:



Diseases related to Intracranial Abscess

Symptoms & Phenotypes for Intracranial Abscess

MGI Mouse Phenotypes related to Intracranial Abscess:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.43 BIN1 CRP LATS2 LIG3 NEU1 TWIST1
2 muscle MP:0005369 9.02 BIN1 LATS2 LIG3 NEU1 TWIST1

Drugs & Therapeutics for Intracranial Abscess

Drugs for Intracranial Abscess (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carbon monoxide Approved, Investigational Phase 1 630-08-0 281

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 A Clinical Trial of the Clinical Effects of Hyperbaric Oxygen Therapy in Thai Autistic Children Completed NCT00670891 Phase 1
2 Fast Magnetic Resonance Imaging as Compared to Computed Tomography Scan in Pediatric Orbital Cellulitis Imaging Unknown status NCT02711436 Not Applicable
3 Effects of Repetitive Hyperbaric Oxygen Therapy in Patients With Acute Ischaemic Stroke Recruiting NCT03431402 Not Applicable Hyperbaric oxygen
4 Hyperbaric Oxygen Therapy Registry Enrolling by invitation NCT02483650

Search NIH Clinical Center for Intracranial Abscess

Genetic Tests for Intracranial Abscess

Anatomical Context for Intracranial Abscess

The Foundational Model of Anatomy Ontology organs/tissues related to Intracranial Abscess:

19
The Skull

MalaCards organs/tissues related to Intracranial Abscess:

41
Bone, Brain, Parietal Lobe

Publications for Intracranial Abscess

Articles related to Intracranial Abscess:

(show top 50) (show all 94)
# Title Authors Year
1
Hyperbaric, Intracranial Abscess ( 29630279 )
2018
2
A Headache from Our Past? Intracranial Abscess Disease, Virulence Factors of Trueperella pyogenes, and a Legacy of Translocating White-Tailed Deer. ( 29878877 )
2018
3
Methicillin-resistant <i>Staphylococcus aureus</i> intracranial abscess: An analytical series and review on molecular, surgical and medical aspects. ( 29735835 )
2018
4
A Unique Presentation of an Intracranial Abscess Secondary to Retained Projectile after Debridement with Dural Closure. ( 28690961 )
2017
5
Interpretation of Postoperative Intracranial Abscess. ( 28005503 )
2017
6
Intracranial abscess formation following sphenoid sinus occlusion with nasoseptal flap skull base reconstruction: A cautionary tale. ( 29236280 )
2017
7
Postoperative versus Spontaneous Intracranial Abscess: Diagnostic Value of the Apparent Diffusion Coefficient for Accurate Assessment. ( 27027334 )
2016
8
Intracranial abscess as a complication of X-linked agammaglobulinemia. ( 27550432 )
2016
9
Neurological melioidosis presenting as intracranial abscess. ( 27510695 )
2016
10
Intracranial Abscess Presenting as Periorbital Edema of Graves Disease. ( 27159867 )
2016
11
Streptococcus Pneumoniae Intracranial Abscess and Post-Infectious Vasculitis. ( 28191299 )
2016
12
Textiloma (gossypiboma) mimicking recurrent intracranial abscess. ( 26318152 )
2015
13
Intracranial abscess due to Mycobacterium avium complex in an immunocompetent host: a case report. ( 26201464 )
2015
14
Balloon frontal sinuplasty for intracranial abscess in a pediatric acute sinusitis patient. ( 25636667 )
2015
15
Intracranial abscess in Ectopia Cordis. ( 25153988 )
2014
16
Hodgkin's Lymphoma of the Temporal Bone Accompanied by Intracranial Abscess. ( 24270717 )
2014
17
Intracranial abscess as a complication of allergic fungal sinusitis. ( 22211876 )
2014
18
A single aspergillus fumigatus intracranial abscess in an immunocompetent patient with parietal lobe tumorectomy. ( 24906819 )
2014
19
Intracranial abscess secondary to dental infection. ( 24665546 )
2014
20
An autopsy case of otogenic intracranial abscess and meningitis with Bezold's abscess: evaluation of inflammatory bone destruction by postmortem cone-beam CT. ( 24112990 )
2013
21
Shunt-related intracranial abscess caused by Staphylococcus lugdunensis in a hydranencephalic patient. ( 23321380 )
2013
22
Intracranial abscess as a complication of nasal septal abscess. ( 22949564 )
2013
23
Intracranial abscess. ( 22670553 )
2012
24
Primary intracranial abscess localized in the basal ganglia: a case report. ( 21320856 )
2012
25
Role of CT Scan in Diagnosis and Management of Otogenic Intracranial Abscess. ( 22754809 )
2011
26
Canine parvovirus type 2c infection in a kitten associated with intracranial abscess and convulsions. ( 21208817 )
2011
27
Single stage, transmastoid approach for otogenic intracranial abscess. ( 19607739 )
2009
28
Surgical management of a canine intracranial abscess due to a bite wound. ( 19821895 )
2009
29
Symptomatic intracranial abscess after treating lower cervical spine fracture with halo vest: a case report and review of literature. ( 19178714 )
2009
30
Intracranial abscess after anterior skull base defect: does pneumocephalus play a role? ( 19839252 )
2009
31
Unusual complications and presentations of intracranial abscess: experience of a single institution. ( 17707481 )
2008
32
Intracranial abscess from embolic Serratia marcescens endocarditis. ( 17714676 )
2007
33
Invasive nontypeable Haemophilus influenzae infections in Germany: a case report of a previously healthy 7-year-old boy with an intracranial abscess, and epidemiological data from 2001 to 2004. ( 16721541 )
2006
34
Intracranial abscess caused by Rhodococcus equi infection in a foal. ( 16426201 )
2006
35
Successful medical treatment of intracranial abscess caused by Brucella spp. ( 15979495 )
2005
36
Intracranial abscesses associated with chronic suppurative otitis media. ( 15959795 )
2005
37
Epidural intracranial abscess as a complication of frontal sinusitis: case report and review of the literature. ( 15043336 )
2004
38
A case of intracranial abscess due to Brucella melitensis. ( 15494262 )
2004
39
Recurrent intracranial abscess after a long latency. ( 15702844 )
2004
40
Oncodiagnosis panel: 2002. Primary glial neoplasm or less likely an intracranial abscess. ( 14635616 )
2003
41
Intracranial abscess as a complication of subperiosteal abscess of the orbit. ( 11766018 )
2001
42
Huge congenital cholesteatoma simulating an intracranial abscess. ( 10889499 )
2000
43
Delayed presentation of an intracranial abscess after a sledding accident. ( 10999597 )
2000
44
Short course antimicrobial therapy in intracranial abscess. ( 11201653 )
2000
45
Delayed intracranial abscess after acoustic neuroma surgery: a report of two cases. ( 10337980 )
1999
46
Intractable meningitis and intracranial abscess following sinusitis due to Candida species. ( 9787599 )
1998
47
Treatment of intracranial abscess in the era of neuroimaging: an analysis of 13 consecutive cases. ( 11186202 )
1998
48
Haemophilus paraphrophilus; a rare cause of intracranial abscess. ( 9733388 )
1998
49
Nasopharyngeal carcinoma presenting as an intracranial abscess. ( 9586935 )
1998
50
Postoperative intracranial abscess--clinical aspects in the differential diagnosis to early recurrence of malignant glioma. ( 9637198 )
1998

Variations for Intracranial Abscess

Expression for Intracranial Abscess

Search GEO for disease gene expression data for Intracranial Abscess.

Pathways for Intracranial Abscess

GO Terms for Intracranial Abscess

Biological processes related to Intracranial Abscess according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA ligation GO:0006266 8.62 LIG3 MGMT

Sources for Intracranial Abscess

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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