Intracranial Arteriosclerosis

Categories: Cardiovascular diseases

Aliases & Classifications for Intracranial Arteriosclerosis

MalaCards integrated aliases for Intracranial Arteriosclerosis:

Name: Intracranial Arteriosclerosis 12 15 74


External Ids:

Disease Ontology 12 DOID:13097
MeSH 45 D002537
UMLS 74 C0007771

Summaries for Intracranial Arteriosclerosis

MalaCards based summary : Intracranial Arteriosclerosis is related to cerebral atherosclerosis. An important gene associated with Intracranial Arteriosclerosis is SELP (Selectin P). The drugs Atorvastatin and Citalopram have been mentioned in the context of this disorder. Affiliated tissues include kidney, brain and testes.

Wikipedia : 77 Atherosclerosis is a disease in which the inside of an artery narrows due to the build up of plaque.... more...

Related Diseases for Intracranial Arteriosclerosis

Diseases related to Intracranial Arteriosclerosis via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 cerebral atherosclerosis 11.4

Symptoms & Phenotypes for Intracranial Arteriosclerosis

Drugs & Therapeutics for Intracranial Arteriosclerosis

Drugs for Intracranial Arteriosclerosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 202)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Atorvastatin Approved Phase 4,Early Phase 1 134523-00-5 60823
Citalopram Approved Phase 4,Phase 3 59729-33-8 2771
Aspirin Approved, Vet_approved Phase 4,Phase 3,Phase 2 50-78-2 2244
Cilostazol Approved, Investigational Phase 4,Phase 3 73963-72-1 2754
Probucol Approved, Investigational Phase 4 23288-49-5 4912
Lisinopril Approved, Investigational Phase 4 83915-83-7, 76547-98-3 5362119
Atenolol Approved Phase 4 29122-68-7 2249
Metoprolol Approved, Investigational Phase 4 37350-58-6, 51384-51-1 4171
Propranolol Approved, Investigational Phase 4 525-66-6 4946
Hydrocodone Approved, Illicit, Investigational Phase 4 125-29-1 5284569
Acetaminophen Approved Phase 4,Phase 2 103-90-2 1983
Oxycodone Approved, Illicit, Investigational Phase 4 76-42-6 5284603
Guaifenesin Approved, Investigational, Vet_approved Phase 4 93-14-1 3516
Donepezil Approved Phase 4,Phase 3,Phase 1 120014-06-4 3152
tannic acid Approved Phase 4 1401-55-4
Benzocaine Approved, Investigational Phase 4 1994-09-7, 94-09-7 2337
Calcium Approved, Nutraceutical Phase 4,Phase 3,Not Applicable 7440-70-2 271
Corticosterone Experimental Phase 4 50-22-6 5753
19 Antimetabolites Phase 4,Phase 3,Phase 2,Early Phase 1
20 Rosuvastatin Calcium Phase 4 147098-20-2
21 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4,Phase 2,Early Phase 1
22 Anticholesteremic Agents Phase 4,Phase 2,Early Phase 1
23 Lipid Regulating Agents Phase 4,Phase 3,Phase 2,Early Phase 1
24 Hypolipidemic Agents Phase 4,Phase 3,Phase 2,Early Phase 1
25 Calcium, Dietary Phase 4,Phase 3,Not Applicable
26 Antidepressive Agents Phase 4,Phase 3
27 Autonomic Agents Phase 4,Phase 2,Phase 3
28 Neurotransmitter Uptake Inhibitors Phase 4,Phase 2,Phase 3
29 Parasympatholytics Phase 4
30 Peripheral Nervous System Agents Phase 4,Phase 2,Phase 3
31 Serotonin Uptake Inhibitors Phase 4,Phase 3
32 Psychotropic Drugs Phase 4,Phase 3,Phase 2
33 Serotonin Agents Phase 4,Phase 3
34 Muscarinic Antagonists Phase 4
35 Antidepressive Agents, Second-Generation Phase 4,Phase 3
36 Neurotransmitter Agents Phase 4,Phase 2,Phase 3,Phase 1,Not Applicable
37 Cholinergic Antagonists Phase 4
38 Antiparkinson Agents Phase 4
39 Cholinergic Agents Phase 4,Phase 2,Phase 3,Phase 1
40 Phosphodiesterase Inhibitors Phase 4,Phase 3,Phase 2
41 Nootropic Agents Phase 4,Phase 2,Phase 3,Phase 1
42 Cholinesterase Inhibitors Phase 4,Phase 2,Phase 3,Phase 1
43 Phosphodiesterase 3 Inhibitors Phase 4,Phase 3
44 Protective Agents Phase 4,Phase 3,Phase 2,Not Applicable
45 Fibrinolytic Agents Phase 4,Phase 3
46 Platelet Aggregation Inhibitors Phase 4,Phase 3,Not Applicable
47 Bronchodilator Agents Phase 4,Phase 3
48 Respiratory System Agents Phase 4,Phase 3
49 Vasodilator Agents Phase 4,Phase 3,Phase 2,Not Applicable
50 Antioxidants Phase 4,Phase 2

Interventional clinical trials:

(show top 50) (show all 118)
# Name Status NCT ID Phase Drugs
1 Intensive Statin Treatment in Acute Ischemic Stroke Patients With INtracranial Atherosclerosis Unknown status NCT02458755 Phase 4 High-dose statin: Atorvastatin 40mg or Rosuvastatin 20mg
2 Study of Escitalopram Versus Placebo in the Treatment of Depressive Syndrome in Alzheimer’s Disease, Vascular Dementia, and Mixed Vascular and Alzheimer’s Dementia Unknown status NCT00229333 Phase 4 Escitalopram
3 Clinical Trial of Efficacy and Safety of Divaza in the Management of Oxidative Disturbances in Cerebral Atherosclerosis Completed NCT03485495 Phase 4 Divaza;Placebo
4 Study of Cilostazol and Probucol Alone and in Combination on Atherosclerosis Related Biomarker---atherosclerosis Cerebral Infarction Patient as Study Subject Completed NCT00823875 Phase 4 Cilostazol group;Probucol group;Cilostazol + Probucol group;control group
5 Reducing Total Cardiovascular Risk in an Urban Community Completed NCT00241904 Phase 4 Antiplatelet Agents;Beta Blocker;ACE Inhibitors
6 A Clinical Trial to Evaluate the Safety and Efficacy of 20 ml Cerebrolysin in Patients With Vascular Dementia Completed NCT00947531 Phase 4 Cerebrolysin;0.9% Saline Solution
7 Cilostazol Verse Asprin for Vascular Dementia in Poststroke Patients With White Matter Lesions Completed NCT00847860 Phase 4 Cilostazol;Aspirin
8 Low-Dose Opiate Therapy for Discomfort in Dementia (L-DOT) Completed NCT00385684 Phase 4 hydrocodone/APAP w placebo PRN;hydrocodone/APAP;placebo with hydrocodone/APAP PRN
9 Efficacy and Safety of Donepezil Hydrochloride (Aricept) in Vascular Dementia Completed NCT00165763 Phase 4 donepezil hydrochloride (Aricept)
10 The Effect of InTensive Statin in Ischemic Stroke With inTracranial Atherosclerotic Plaques Recruiting NCT03753555 Phase 4 Atorvastatin Calcium;Atorvastatin Calcium;Probucol
11 Imaging of Brain Amyloid Plaques in the Aging Population Enrolling by invitation NCT00950430 Phase 4 Pittsburgh Compound B (C-11 PiB);F-18 FDG;Tau (18-F-AV-1451)
12 Strategy for Adequate Blood Pressure Lowering in the Patients With Intracranial Atherosclerosis Terminated NCT01104311 Phase 4
13 Symptomatic Treatment of Vascular Cognitive Impairment Unknown status NCT02098824 Phase 2, Phase 3 Galantamine;Methylphenidate;Placebo
14 Evaluating the Effects of Music Interventions on Hospitalised People With Dementia Unknown status NCT00448318 Phase 2, Phase 3
15 Cilostazol-Aspirin Therapy Against Recurrent Stroke With Intracranial Artery Stenosis Completed NCT00333164 Phase 3 Asprin, Cilostazol
16 Cholesterol-Lowering Atherosclerosis Study (CLAS) Completed NCT00000599 Phase 3 colestipol;niacin
17 Efficacy and Safety of Tianzhi Granule in Mild to Moderate Vascular Dementia Completed NCT02453932 Phase 3 Tianzhi granule and placebo identified to donepezil;Donepezil and placebo identified to Tianzhi granule;Placebo
18 Seroquel- Agitation Associated With Dementia Completed NCT00621647 Phase 3 Quetiapine Fumarate;Quetiapine Fumarate;Placebo
19 A Study of the Safety and Effectiveness of Galantamine Versus Placebo in the Treatment of Patients With Vascular Dementia or Mixed Dementia Completed NCT00261573 Phase 3 galantamine hydrobromide
20 A Study of the Effectiveness and Safety of Risperidone Versus Placebo in the Treatment of Behavioral Disturbances in Patients With Dementia Completed NCT00253123 Phase 3 risperidone
21 A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia Completed NCT00249158 Phase 3 Risperidone
22 A Study of the Effectiveness and Safety of Risperidone in the Treatment of Behavioral Disturbances in Patients With Dementia Completed NCT00249145 Phase 3 risperidone
23 Dopamine Transporter Scintigraphy Imaging (DAT-Imaging) in Patients With Lewy Body Dementia Completed NCT00209456 Phase 3 DatSCAN
24 Donepezil Hydrochloride (E2020) in Dementia Associated With Cerebrovascular Disease Completed NCT00165737 Phase 3 Donepezil Hydrochloride
25 Rivastigmine Capsules in Patients With Probable Vascular Dementia Completed NCT00130338 Phase 3 Rivastigmine
26 Efficacy and Safety of Rivastigmine Capsules in Patients With Probable Vascular Dementia Completed NCT00099216 Phase 3 Rivastigmine
27 A Placebo-controlled Trial to Evaluate the Safety and Efficacy of Galantamine in the Treatment of Vascular Dementia Completed NCT00035191 Phase 3 galantamine
28 Serotonergic Pharmacotherapy for Agitation of Dementia Completed NCT00009204 Phase 3 Citalopram [Celexa];Perphenazine [Trilafon]
29 Optimized Remote Ischemic Conditioning (RIC) Treatment for Patients With Chronic Cerebral Ischemia Recruiting NCT03105141 Phase 2, Phase 3
30 The Clinical Trial of Chinese Herbal Medicine (SaiLuoTong) Capsule Recruiting NCT03789760 Phase 3 SaiLuoTong capsule;placebo
31 The Healthy Patterns Study Recruiting NCT03682185 Phase 3
32 MIND Diet Intervention and Cognitive Decline Active, not recruiting NCT02817074 Phase 3
33 Angioplasty and Stenting for Patients With Symptomatic Intracranial Atherosclerosis Not yet recruiting NCT02689037 Phase 3 Aspirin plus clopidogrel
34 Efficacy and Safety of Butylphthalide Soft Capsule for the Treatment of Vascular Dementia Not yet recruiting NCT03804229 Phase 3 Butylphthalide soft capsule;Placebo soft capsule
35 Triple Therapy Prevention of Recurrent Intracerebral Disease EveNts Trial (TRIDENT) Cognitive Sub-Study Not yet recruiting NCT03785067 Phase 3 telmisartan 20mg + amlodipine 2.5mg +indapamide 1.25mg;Placebo oral capsule
36 Vaspect Study - An Open-Label Trial Of Donepezil in Vascular and Mixed Dementia Terminated NCT00174382 Phase 3 Donepezil
37 The Clinical Trial of Chinese Herbal Medicine SaiLuoTong Capsule Unknown status NCT01978730 Phase 2 high dose group of SaiLuoTong capsule;low dose group of SaiLuoTong;the control group
38 Effect of Zydena (Udenafil) on Cerebral Blood Flow and Peripheral Blood Viscosity Unknown status NCT01466543 Phase 2 Zydena (Udenafil);Placebo
39 Asymptomatic Carotid Artery Plaque Study (ACAPS) Completed NCT00000469 Phase 2 aspirin;lovastatin
40 DAOIB for the Treatment of Cognitive Function and Behavioral and Psychological Symptoms of Dementia Completed NCT02103673 Phase 2 DAOIB;Placebo
41 Effect of Insulin Sensitizer Metformin on AD Biomarkers Completed NCT01965756 Phase 2 Metformin;Placebos
42 Efficacy and Safety of Fufangdanshen Tablets in Mild to Moderate Vascular Dementia Completed NCT01761227 Phase 2 Fufangdanshen Tablets;Placebo
43 Delta-THC in Dementia Completed NCT01608217 Phase 2 delta-9-tetrahydrocannabinol (delta-THC);Placebo;Acetaminophen;Acetaminophen
44 Study of STA-1 Capsule in Patients With Vascular Dementia (Marrow-Sea Deficiency) Completed NCT01475578 Phase 2 STA-1;Ergoloid Mesylates tablet
45 Efficacy and Safety of TMBCZG in Mild to Moderate Vascular Dementia Recruiting NCT03230071 Phase 2 TMBCZG
46 A Study to Evaluate Efficacy and Safety of BAC in Patient With Alzheimer's Disease or Vascular Dementia Recruiting NCT02886494 Phase 2 BAC;Matched placebo
47 Perfusion by Arterial Spin Labelling Following Single Dose Tadalafil in Small Vessel Disease (PASTIS) Trial Active, not recruiting NCT02450253 Phase 2 Tadalafil;Placebo
48 n-3 PUFA for Vascular Cognitive Aging Active, not recruiting NCT01953705 Phase 2 Omega 3 PUFA;Placebo
49 Prevention for the Restenosis of Intracranial Artery Stent Implantation Treated With Herbal Medicine C117 Not yet recruiting NCT03008798 Phase 2 Herbal Medicine C-117;The Placebo of Herbal Medicine C-117
50 Efficacy and Safety of Ferrous Iron on the Prevention of Vascular Cognitive Impairment Among Patients With Cerebral Infarction/TIA (FAVORITE) Not yet recruiting NCT03891277 Phase 2 Ferrous succinate

Search NIH Clinical Center for Intracranial Arteriosclerosis

Genetic Tests for Intracranial Arteriosclerosis

Anatomical Context for Intracranial Arteriosclerosis

MalaCards organs/tissues related to Intracranial Arteriosclerosis:

Kidney, Brain, Testes, Bone, Retina

Publications for Intracranial Arteriosclerosis

Variations for Intracranial Arteriosclerosis

Expression for Intracranial Arteriosclerosis

Search GEO for disease gene expression data for Intracranial Arteriosclerosis.

Pathways for Intracranial Arteriosclerosis

GO Terms for Intracranial Arteriosclerosis

Sources for Intracranial Arteriosclerosis

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
33 HPO
34 ICD10
35 ICD10 via Orphanet
39 LifeMap
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
56 Novoseek
59 OMIM via Orphanet
63 PubMed
71 SNOMED-CT via Orphanet
73 Tocris
75 UMLS via Orphanet
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