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MCID: INT260
MIFTS: 39

Intracranial Berry Aneurysm

Categories: Cardiovascular diseases, Genetic diseases, Neuronal diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Intracranial Berry Aneurysm

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MalaCards integrated aliases for Intracranial Berry Aneurysm:

Name: Intracranial Berry Aneurysm 12 15
Familial Aneurysmal Subarachnoid Hemorrhage 12
Familial Intracranial Saccular Aneurysm 12
Aneurysmal Subarachnoid Hemorrhage 15
Aneurysm, Intracranial Berry, 1 70
Aneurysm, Intracranial Berry 73
Saccular Cerebral Aneurysm 12
Familial Berry Aneurysm 12

Classifications:

MalaCards categories:
Global: Genetic diseases Rare diseases
Anatomical: Cardiovascular diseases Neuronal diseases
See all MalaCards categories (disease lists)
ICD10: 32


External Ids:

Disease Ontology 12 DOID:0060228
ICD10 32 I60.7
UMLS 70 C1862932
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Summaries for Intracranial Berry Aneurysm

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Disease Ontology : 12 An intracranial aneurysm with a characteristic rounded shape; the most common form of cerebral aneurysm.

MalaCards based summary : Intracranial Berry Aneurysm, also known as familial aneurysmal subarachnoid hemorrhage, is related to ischemia and intracranial aneurysm. An important gene associated with Intracranial Berry Aneurysm is ANIB1 (Aneurysm, Intracranial Berry 1), and among its related pathways/superpathways are Oxytocin signaling pathway and HIF-1 signaling pathway. The drugs Propofol and Gabapentin have been mentioned in the context of this disorder. Affiliated tissues include spinal cord, endothelial and pituitary.

Wikipedia : 73 An intracranial aneurysm, also known as a brain aneurysm, is a cerebrovascular disorder in which... more...

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Related Diseases for Intracranial Berry Aneurysm

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Diseases in the Intracranial Berry Aneurysm family:

Aneurysm, Intracranial Berry, 1 Aneurysm, Intracranial Berry, 5
Aneurysm, Intracranial Berry, 2 Aneurysm, Intracranial Berry, 3
Aneurysm, Intracranial Berry, 4 Aneurysm, Intracranial Berry, 6
Aneurysm, Intracranial Berry, 7 Aneurysm, Intracranial Berry, 8
Aneurysm, Intracranial Berry, 9 Aneurysm, Intracranial Berry, 10
Aneurysm, Intracranial Berry, 11 Aneurysm, Intracranial Berry, 12

Diseases related to Intracranial Berry Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 286)
# Related Disease Score Top Affiliating Genes
1 ischemia 32.3 PLAT NOS3 HMOX1 EDN1 ADM
2 intracranial aneurysm 32.2 PLAT PKD1 NOS3
3 pulmonary edema 31.9 NOS3 HMOX1 EDN1
4 migraine with or without aura 1 31.2 S100B NOS3 EDN1 ADM
5 cardiogenic shock 31.1 PLAT ADM
6 stroke, ischemic 31.1 SERPINA3 PLAT NOS3 ADM
7 kidney disease 31.0 SERPINA3 PKD1 NOS3 HMOX1 EDN1 ADM
8 limb ischemia 31.0 PLAT NOS3 EDN1
9 myocardial infarction 30.9 SERPINA3 S100B PLAT NOS3 HMOX1 EDN1
10 intracranial vasospasm 30.9 S100B EDN3
11 aneurysm 30.9 ANIB4 ANIB3 ANIB2 ANIB1
12 renal hypertension 30.8 NOS3 EDN1 ADM
13 sickle cell disease 30.7 NOS3 HMOX1 EDN1
14 cardiovascular system disease 30.7 SERPINA3 PLAT NOS3 HMOX1 EDN1 ADM
15 hellp syndrome 30.7 PLAT EDN1 ADM
16 coronary artery vasospasm 30.6 NOS3 EDN1
17 aneurysm, intracranial berry, 12 11.8
18 aneurysm, intracranial berry, 9 11.5
19 aneurysm, intracranial berry, 10 11.5
20 aneurysm, intracranial berry, 11 11.5
21 acquired aneurysmal subarachnoid hemorrhage 11.4
22 polycystic kidney disease 1 with or without polycystic liver disease 11.3
23 aneurysm, intracranial berry, 5 11.3
24 aneurysm, intracranial berry, 2 11.3
25 aneurysm, intracranial berry, 3 11.3
26 aneurysm, intracranial berry, 4 11.3
27 aneurysm, intracranial berry, 6 11.3
28 aneurysm, intracranial berry, 7 11.3
29 aneurysm, intracranial berry, 8 11.3
30 hydrocephalus 11.3
31 familial cerebral saccular aneurysm 11.2
32 ocular motor apraxia 11.1
33 headache 10.8
34 hyperglycemia 10.7
35 intracranial hypertension 10.7
36 brain injury 10.7
37 traumatic brain injury 10.7
38 atrial standstill 1 10.6
39 seizure disorder 10.6
40 pituitary gland disease 10.6
41 hypopituitarism 10.6
42 aphasia 10.5
43 cerebrovascular disease 10.5
44 eisenmenger syndrome 10.5 PLAT EDN1
45 central retinal artery occlusion 10.5 PLAT HMOX1 EDN1
46 middle cerebral artery infarction 10.5 S100B PLAT EDN1
47 acute mountain sickness 10.5 S100B NOS3 EDN1
48 hepatopulmonary syndrome 10.5 NOS3 HMOX1 EDN1
49 acute chest syndrome 10.5 NOS3 HMOX1 EDN1
50 diabetic angiopathy 10.5 NOS3 EDN1 ADM

Graphical network of the top 20 diseases related to Intracranial Berry Aneurysm:



Diseases related to Intracranial Berry Aneurysm
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Symptoms & Phenotypes for Intracranial Berry Aneurysm

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Drugs & Therapeutics for Intracranial Berry Aneurysm

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Drugs for Intracranial Berry Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 128)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
2
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
3
Desflurane Approved Phase 4 57041-67-5 42113
4
Nicardipine Approved, Investigational Phase 4 55985-32-5 4474
5
Verapamil Approved Phase 4 52-53-9 2520
6
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
7
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
8 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 4
9 Hypnotics and Sedatives Phase 4
10 Psychotropic Drugs Phase 4
11 Anti-Anxiety Agents Phase 4
12 Anesthetics, Inhalation Phase 4
13 Anti-Arrhythmia Agents Phase 4
14 Respiratory System Agents Phase 4
15 Neuroprotective Agents Phase 4
16 Anti-Asthmatic Agents Phase 4
17 Bronchodilator Agents Phase 4
18 Epoetin alfa Phase 4 113427-24-0
19 Hematinics Phase 4
20
Ketamine Approved, Vet_approved Phase 2, Phase 3 6740-88-1 3821
21
Dexmedetomidine Approved, Vet_approved Phase 3 113775-47-6 5311068 68602
22
Nimodipine Approved, Investigational Phase 3 66085-59-4 4497
23
Cerebrolysin Experimental Phase 2, Phase 3 12656-61-0
24 Astragalus Phase 2, Phase 3
25 Tin Fluorides Phase 3
26 Fibrinolytic Agents Phase 3
27 Neurotransmitter Agents Phase 2, Phase 3
28 Anesthetics Phase 2, Phase 3
29 Anesthetics, General Phase 2, Phase 3
30 Analgesics Phase 2, Phase 3
31 Anesthetics, Intravenous Phase 2, Phase 3
32 Tissue Plasminogen Activator Phase 3
33 Plasminogen Phase 3
34 Excitatory Amino Acid Antagonists Phase 2, Phase 3
35 Anesthetics, Dissociative Phase 2, Phase 3
36 Calcium, Dietary Phase 3
37 Antihypertensive Agents Phase 3
38 calcium channel blockers Phase 3
39 Hormones Phase 3
40 Adrenergic alpha-Agonists Phase 3
41 Adrenergic Agonists Phase 3
42 Adrenergic Agents Phase 3
43
Calcium Nutraceutical Phase 3 7440-70-2 271
44
Clevidipine Approved, Investigational Phase 2 167221-71-8
45
tannic acid Approved Phase 1, Phase 2 1401-55-4
46
Benzocaine Approved, Investigational Phase 1, Phase 2 1994-09-7, 94-09-7 2337
47
Minocycline Approved, Investigational Phase 1, Phase 2 10118-90-8 5281021
48
acetic acid Approved Phase 2 64-19-7 176
49
Heparin Approved, Investigational Phase 2 9005-49-6 772 9812414
50
Dalteparin Approved Phase 2 9005-49-6

Interventional clinical trials:

(show top 50) (show all 103)
# Name Status NCT ID Phase Drugs
1 The Role of Statins in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage Unknown status NCT01346748 Phase 4 statin
2 Gabapentin for Headache in Aneurysmal Subarachnoid Hemorrhage Completed NCT02330094 Phase 4 Gabapentin;Placebo
3 Comparison Of Pharmacological Neuroprotection Provided By PROPOFOL VERSUS DESFLURANE For Long Term Postoperative Cognitive Dysfunction In Patients Undergoing Surgery For Aneurysmal Subarachnoid Hemorrhage Completed NCT02987218 Phase 4 Propofol;Desflurane
4 The Intra-arterial Vasospasm Trial(iVAST)- A Multi-center Randomized Study Recruiting NCT01996436 Phase 4 Nicardipine;Verapamil;Nicardipine + Verapamil + Nitroglycerin
5 Efficacy and Safety of Cilostazol-Nimodipine Combined Therapy on Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage (aSAH): A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial Recruiting NCT04148105 Phase 4 Cilostazol 100 MG
6 A Double Blinded, Placebo Controlled, Pilot Study to Evaluate the Safety of Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
7 Pilot Study of Seizure Prophylaxis With Levetiracetam in Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT01935908 Phase 4 levetiracetam
8 Efficacy Study of Astragalus Membranaceus on Aneurysmal Subarachnoid Hemorrhage Unknown status NCT03271697 Phase 2, Phase 3 Astragalus Membranaceus;Placebo
9 EARLYdrain - Prospective Outcome Study of Early Lumbar Drainage in Aneurysmal Subarachnoid Hemorrhage Completed NCT01258257 Phase 3
10 A Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Assess the Efficacy and Safety of Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Surgical Clipping. Completed NCT00558311 Phase 3 Clazosentan;Placebo
11 Randomized, Double-blind, Placebo-controlled Pilot Trial to Investigate Safety and Efficacy of Cerebrolysinâ„¢ in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT01787123 Phase 2, Phase 3 Intravenous Cerebrolysin;Normal Saline
12 Aneurysmal Subarachnoid Hemorrhage: Red Blood Cell Transfusion and Outcome - A Pilot Randomized Controlled Trial Completed NCT02483351 Phase 2, Phase 3
13 A Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase 3 Study to Assess the Efficacy and Safety of Clazosentan in Preventing Clinical Deterioration Due to Delayed Cerebral Ischemia (DCI), in Adult Subjects With Aneurysmal Subarachnoid Hemorrhage (aSAH) Recruiting NCT03585270 Phase 3 Clazosentan;Placebo
14 Intraventricular Fibrinolysis Versus External Ventricular Drainage Alone in Aneurysmal Subarachnoid Hemorrhage: a Randomized Controlled Trial. Recruiting NCT03187405 Phase 3 EVD + IVF with Alteplase
15 Aneurysmal Subarachnoid Hemorrhage - Red Blood Cell Transfusion and Outcome (SAHaRA): A Randomized Controlled Trial Recruiting NCT03309579 Phase 3
16 A Pilot Study of Sub-anesthetic Ketamine Infusion for Neuroprotection After Aneurysmal Subarachnoid Hemorrhage: Effects on White Matter Integrity, Inflammatory Biomarkers and Neurocognitive Outcome Recruiting NCT02636218 Phase 2, Phase 3 Ketamine;0.9% NaCl
17 Effects of Dexmedetomidine on Inflammatory Cytokines in Patients With Aneurysmal Subarachnoid Hemorrhage Terminated NCT01565590 Phase 3 Dexmedetomidine;propofol
18 A Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Assess the Efficacy and Safety of Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Endovascular Coiling. Terminated NCT00940095 Phase 3 Clazosentan 5 m/h;Clazosentan 15 mg/h;Placebo
19 Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Study Comparing EG-1962 to Standard of Care Oral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage Terminated NCT02790632 Phase 3 EG-1962 (nimodipine microparticles);Enteral Nimodipine
20 Prevention of Secondary Ischemia After Aneurysmal Subarachnoid Hemorrhage With Cerebrospinal Fluid Drainage. A Randomized Controlled Trial Terminated NCT01407614 Phase 2, Phase 3
21 Intraventricular Tissue Plasminogen Activator in the Management of Aneurysmal Subarachnoid Hemorrhage: a Randomized Controlled Pilot Study Unknown status NCT01098890 Phase 2 Tissue Plasminogen Activator;Placebo
22 Clevidipine in Aneurysmal Subarachnoid Hemorrhage, A Pilot Study Unknown status NCT00978822 Phase 2 Clevidipine butyrate injectable emulsion
23 Hypertonic Saline Solution in Aneurysmal Subarachnoid Hemorrhage: A Randomized - Phase II Single Blinded Clinical Trial Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
24 Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial Unknown status NCT02875262 Phase 1, Phase 2 Deferoxamine
25 Minocycline as Neuroprotectant After Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02113176 Phase 1, Phase 2 Minocycline
26 A Prospective, Multi-center, Open-label, Single-arm, Phase 2 Study to Assess the Efficacy and Safety of Clazosentan in Reversing Angiographically-confirmed Cerebral Vasospasm in Adult Subjects With Aneurysmal Subarachnoid Hemorrhage (aSAH) Treated by Surgical Clipping or Endovascular Coiling Completed NCT02560532 Phase 2 Clazosentan
27 Effects of Systemic Erythropoietin Therapy on Cerebral Autoregulation and Incidence of Delayed Ischemic Deficits in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT00140010 Phase 2 erythropoietin beta
28 Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage Completed NCT01095731 Phase 2 Tiopronin;Placebo
29 A Phase IIb, Multi-center, International, Double-blind, Randomized, Placebo-controlled, Parallel-group, Dose-finding Study for the Prevention of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage (aSAH) by Intravenous Administration of Clazosentan, a Selective Endothelin A (ETA) Receptor Antagonist Completed NCT00111085 Phase 2 Clazosentan 1 mg/h;Clazosentan 5 mg/h;Clazosentan 15 mg/h;Placebo
30 OSU6162 in the Treatment of Fatigue and Other Neuropsychological Sequelae After Aneurysmal Subarachnoid Hemorrhage - A Double-blind, Randomised, Placebo-controlled Study Completed NCT03209830 Phase 2 OSU 6162;Placebo Oral Tablet
31 Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After subarachNoid Hemorrhage: Phase I/IIa Multicenter, Controlled, Randomized, Open Label, Dose Escalation, Safety, Tolerability, and Pharmacokinectic Study Comparing EG-1962 and Nimodipine in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
32 Single Escalating-dose, Open-label Study to Assess the Safety and Effect of SANGUINATEâ„¢ Infusion in Patients at Risk of Delayed Cerebral Ischemia (DCI) After Acute Aneurysmal Subarachnoid Hemorrhage (SAH) Completed NCT02323685 Phase 2
33 A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients With Significant Hemorrhage Burden Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
34 A Phase IIb: Randomised, Single-Blind, Safety, Tolerability, Efficacy and Pharmacokinetic Study of NicaPlant® in Aneurysmal Subarachnoid Haemorrhage Patients Undergoing Aneurysm Clipping Recruiting NCT04269408 Phase 2 Nicardipine
35 Improving Outcome in Subarachnoid Hemorrhage wIth Nadroparine Not yet recruiting NCT04507178 Phase 2 Nadroparin Injectable Product
36 Efficacy of 10 Days Intravenous Milrinone Treatment to Optimize Cerebral Hemodynamic and Prevent Delayed Cerebral Ischemia (DCI) in Patients With Severe Subarachnoid Hemorrhage Due to Intracranial Aneurysm Rupture Not yet recruiting NCT04282629 Phase 2 Milrinone Injection
37 Deferoxamine In the Treatment of Aneurysmal Subarachnoid Hemorrhage (DISH) Not yet recruiting NCT04566991 Phase 2 Deferoxamine;Placebo
38 Effect of Xenon on Brain Injury, Neurological Outcome and Survival in Patients After Aneurysmal Subarachnoid Hemorrhage Not yet recruiting NCT04696523 Phase 2 Xenon;air/oxygen
39 Effects of Donepezil on Regional Cerebral Blood Flow Following Aneurysmal Subarachnoid Haemorrhage Terminated NCT02222727 Phase 2 Donepezil
40 Milrinone in Addition to Hyperdynamic Therapy in the Treatment of Vasospasm Following Aneurysmal Subarachnoid Hemorrhage Terminated NCT02712788 Phase 2 Milrinone;Placebo
41 Safety and Efficacy of Cervical Sympathetic Block in Patients With Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage - Pilot Study Terminated NCT00930072 Phase 2 Cervical Sympathetic Block (bupivicaine, clonidine)
42 Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT01878136 Phase 1, Phase 2 Tissue Plasminogen Activator
43 Safety and Efficacy Trial of Sildenafil Citrate in Attenuation of Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT00871065 Phase 2 Sildenafil citrate
44 Therapeutical Hypercapnia to Prevent Secondary Ischemic Events in Aneurysmal Subarachnoid Hemorrhage (aSAH) Completed NCT01799525 Phase 1
45 Cervical Spinal Cord Stimulation for the Prevention of Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage Using MTS Trial System 3510 Completed NCT00766844 Phase 1
46 The Efficacy of Landmark-guided Percutaneous Sphenopalatine Ganglion Block on Self-reported Headache Pain Secondary to Aneurysmal Subarachnoid Hemorrhage: A Feasibility Study Recruiting NCT04331938 Phase 1 Regional anesthetic SPG block-bilateral
47 Multicenter, Controlled, Randomized, Safety and Pharmacokinetic Study Comparing Intracisternal EG-1962 to Standard of Care Enteral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage Terminated NCT02893826 Phase 1 EG-1962 (nimodipine microparticles);Enteral Nimodipine
48 Phase I Safety, Blood Brain Barrier Permeability and Potential Efficacy of Etanercept for Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT01865630 Phase 1 Etanercept
49 Prognostic Value of Circulating Endothelial Progenitor Cells in Aneurysmal Subarachnoid Hemorrhage (Evaluation de l'intérêt Pronostic Des progéniteurs endothéliaux Circulants Dans l'hémorragie Sous-arachnoïdienne Par Rupture d'anévrysme cérébral) Unknown status NCT01773200
50 Non Invasive Measurements of Intracranial Pressure After Aneurysmal Subarachnoid Hemorrhage Unknown status NCT03040284

Search NIH Clinical Center for Intracranial Berry Aneurysm

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Genetic Tests for Intracranial Berry Aneurysm

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Anatomical Context for Intracranial Berry Aneurysm

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MalaCards organs/tissues related to Intracranial Berry Aneurysm:

40
Spinal Cord, Endothelial, Pituitary
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Publications for Intracranial Berry Aneurysm

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Articles related to Intracranial Berry Aneurysm:

(show all 48)
# Title Authors PMID Year
1
Clinical data on rare case of spontaneous disappearance of intracranial Aneurysm. 61
32613046 2020
2
Rare Spontaneous Disappearance of Intracranial Aneurysm. 61
31765869 2020
3
Effect of actual age on outcome at discharge in patients by surgical clipping and endovascular coiling for ruptured cerebral aneurysm in Japan. 61
29335886 2018
4
Thrombosis and recanalization of small saccular cerebral aneurysm : two case reports and a suggestion for possible mechanism. 61
25132936 2014
5
Short-term outcome for saccular cerebral aneurysms treated with the Orbit Galaxy Detachable Coil System. 61
24211142 2014
6
Delayed rebleeding of a spontaneously thrombosed aneurysm after subarachnoid hemorrhage. 61
24818049 2014
7
Fluid structural analysis of human cerebral aneurysm using their own wall mechanical properties. 61
24151523 2013
8
Modelling evolution and the evolving mechanical environment of saccular cerebral aneurysms. 61
20496095 2011
9
Early endovascular coiling of posterior communicating artery saccular aneurysm in the setting of Staphylococcus bacteremia: case report and review of the literature. 61
20305472 2010
10
Infraoptic course of both anterior cerebral arteries. 61
20157384 2010
11
Influence of medial collagen organization and axial in situ stretch on saccular cerebral aneurysm growth. 61
19831480 2009
12
Endothelial nitric oxide synthase tagging single nucleotide polymorphisms and recovery from aneurysmal subarachnoid hemorrhage. 54
19419976 2009
13
A theoretical model for fibroblast-controlled growth of saccular cerebral aneurysms. 61
19027028 2009
14
Modeling of saccular aneurysm growth in a human middle cerebral artery. 61
19045519 2008
15
Expressions of PDGF-B and collagen type III in the remodeling of experimental saccular aneurysm in rats. 61
18489818 2008
16
Endothelial nitric oxide synthase polymorphism (-786T->C) and increased risk of angiographic vasospasm after aneurysmal subarachnoid hemorrhage. 54
18309169 2008
17
Role of endothelial nitric oxide synthase gene polymorphisms in predicting aneurysmal subarachnoid hemorrhage in South Indian patients. 54
18688082 2008
18
A model for saccular cerebral aneurysm growth by collagen fibre remodelling. 61
17482213 2007
19
Update on evidence for a genetic predisposition to cerebral vasospasm. 54
17029342 2006
20
Familial aggregation of both aortic and cerebral aneurysms: evidence for a common genetic basis in a subset of families. 61
15792503 2005
21
Vascular corrosion casts mirroring early morphological changes that lead to the formation of saccular cerebral aneurysm: an experimental study in rats. 61
15796390 2005
22
Endothelin-1 levels in plasma and cerebrospinal fluid of patients with cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 54
15967223 2005
23
Mechanisms of disease: roles of nitric oxide and endothelin-1 in delayed cerebral vasospasm produced by aneurysmal subarachnoid hemorrhage. 54
16265315 2004
24
Prevention of symptomatic vasospasm after aneurysmal subarachnoid hemorrhage by intraoperative cisternal fibrinolysis using tissue-type plasminogen activator combined with continuous cisternal drainage. 54
15686175 2004
25
Section on cerebrovascular surgery: Galbraith Award: Endothelial nitric oxide synthase (eNOS) and heme oxygenase-1 (HO-1) gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage (SAH) and post-SAH cerebral vasospasm. 54
15571165 2004
26
Temporal relationship between endothelin-1 concentrations and cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. 54
11340231 2001
27
Increase and uncoupling of adrenomedullin from the natriuretic peptide system in aneurysmal subarachnoid hemorrhage. 54
11213962 2001
28
Adrenomedullin in patients with cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 54
11108778 2000
29
Vertebral arteriovenous fistula associated with neurofibromatosis type I misdiagnosed as a giant aneurysm. 61
20667184 2000
30
[A case of a traumatic anterior cerebral artery aneurysm following the penetration of the skull base by an iron rod]. 61
10396743 1999
31
Intracranial saccular (berry) aneurysm: a brief overview. 61
9225885 1997
32
Endothelin in cerebral vasospasm. Clinical and experimental results. 54
9385564 1997
33
Innovations in aneurysmal subarachnoid hemorrhage: intracisternal t-PA for the prevention of vasospasm. 54
8718759 1996
34
Current Management of Intracranial Subarachnoid Hemorrhage. 61
27681460 1996
35
[Application of alteplase in prevention of cerebral vasospasm and its sequelae in patients after aneurysmal subarachnoid hemorrhage from ruptured cerebral aneurysm]. 54
7566413 1995
36
Endothelin concentrations in patients with aneurysmal subarachnoid hemorrhage. Correlation with cerebral vasospasm, delayed ischemic neurological deficits, and volume of hematoma. 54
7815135 1995
37
A phase II clinical trial of recombinant human tissue-type plasminogen activator against cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 54
7808602 1994
38
Failure of intracisternal tissue plasminogen activator to prevent vasospasm in certain patients with aneurysmal subarachnoid hemorrhage. 54
8052377 1994
39
The role of endothelin-1 in the origin of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. 54
1607979 1992
40
Variability of expression of the orofaciodigital syndrome type I in black females: six cases. 61
2063902 1991
41
Spontaneous saccular cerebral aneurysm in a rat. 61
2068970 1991
42
Angiographic study of induced cerebral aneurysms in primates. 61
2259401 1990
43
Injection-corrosion cast study of the microcirculation of the brain in haemorrhagic and ischaemic disorders. Preliminary investigation. 61
2795187 1989
44
[Microsurgical treatment of 140 cases of intracranial berry aneurysm]. 61
3830621 1985
45
Management of patients with symptomatic extracranial carotid artery disease and incidental intracranial berry aneurysm. 61
3965749 1985
46
[Rupture of intracranial berry aneurysm complicated with hematoma (author's transl)]. 61
7094754 1982
47
Dominant inheritance of intracranial berry aneurysm. 61
6794716 1981
48
An unusual case of intracranial berry aneurysm co--existing with "subclavian steal" syndrome. 61
5661077 1968
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Variations for Intracranial Berry Aneurysm

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Expression for Intracranial Berry Aneurysm

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Search GEO for disease gene expression data for Intracranial Berry Aneurysm.
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Pathways for Intracranial Berry Aneurysm

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Pathways related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Oxytocin signaling pathway 36
Show member pathways
 11.91 NOS3 EDN3 EDN1 ADM
2
HIF-1 signaling pathway 36
11.47 NOS3 HMOX1 EDN1
3
Fluid shear stress and atherosclerosis 36
11.07 PLAT NOS3 HMOX1 EDN1
4
HIF-1-alpha transcription factor network 1
10.94 HMOX1 EDN1 ADM
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GO Terms for Intracranial Berry Aneurysm

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Biological processes related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.71 PLAT HMOX1 EDN1 ADM
2 regulation of blood pressure GO:0008217 9.63 NOS3 HMOX1 EDN1
3 regulation of vasoconstriction GO:0019229 9.54 EDN3 EDN1
4 vasoconstriction GO:0042310 9.52 EDN3 EDN1
5 inositol phosphate-mediated signaling GO:0048016 9.51 EDN3 EDN1
6 artery smooth muscle contraction GO:0014824 9.49 EDN3 EDN1
7 positive regulation of hormone secretion GO:0046887 9.48 EDN3 EDN1
8 response to fluid shear stress GO:0034405 9.43 PKD1 NOS3
9 positive regulation of prostaglandin-endoperoxide synthase activity GO:0060585 9.37 EDN3 EDN1
10 peptide hormone secretion GO:0030072 9.32 EDN3 EDN1
11 vein smooth muscle contraction GO:0014826 9.26 EDN3 EDN1
12 smooth muscle hyperplasia GO:0014806 9.16 NOS3 HMOX1
13 positive regulation of heart rate GO:0010460 9.13 EDN3 EDN1 ADM
14 regulation of systemic arterial blood pressure by endothelin GO:0003100 8.8 NOS3 EDN3 EDN1

Molecular functions related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.13 EDN3 EDN1 ADM
2 endothelin B receptor binding GO:0031708 8.62 EDN3 EDN1
Sources

Sources for Intracranial Berry Aneurysm

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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