MCID: INT260
MIFTS: 38

Intracranial Berry Aneurysm

Categories: Cardiovascular diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Intracranial Berry Aneurysm

MalaCards integrated aliases for Intracranial Berry Aneurysm:

Name: Intracranial Berry Aneurysm 12 15
Familial Aneurysmal Subarachnoid Hemorrhage 12
Familial Intracranial Saccular Aneurysm 12
Aneurysmal Subarachnoid Hemorrhage 15
Aneurysm, Intracranial Berry, 1 72
Aneurysm, Intracranial Berry 75
Saccular Cerebral Aneurysm 12
Familial Berry Aneurysm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060228
ICD10 33 I60.7
UMLS 72 C1862932

Summaries for Intracranial Berry Aneurysm

Disease Ontology : 12 An intracranial aneurysm with a characteristic rounded shape; the most common form of cerebral aneurysm.

MalaCards based summary : Intracranial Berry Aneurysm, also known as familial aneurysmal subarachnoid hemorrhage, is related to coronary artery vasospasm and intracranial vasospasm. An important gene associated with Intracranial Berry Aneurysm is ANIB1 (Aneurysm, Intracranial Berry 1), and among its related pathways/superpathways is Fluid shear stress and atherosclerosis. The drugs Propofol and Gabapentin have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and endothelial.

Wikipedia : 75 Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in... more...

Related Diseases for Intracranial Berry Aneurysm

Diseases in the Intracranial Berry Aneurysm family:

Aneurysm, Intracranial Berry, 1 Aneurysm, Intracranial Berry, 5
Aneurysm, Intracranial Berry, 2 Aneurysm, Intracranial Berry, 3
Aneurysm, Intracranial Berry, 4 Aneurysm, Intracranial Berry, 6
Aneurysm, Intracranial Berry, 7 Aneurysm, Intracranial Berry, 8
Aneurysm, Intracranial Berry, 9 Aneurysm, Intracranial Berry, 10
Aneurysm, Intracranial Berry, 11

Diseases related to Intracranial Berry Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 282)
# Related Disease Score Top Affiliating Genes
1 coronary artery vasospasm 31.4 NOS3 EDN1
2 intracranial vasospasm 31.4 PLAT NOS3
3 arteries, anomalies of 31.2 PLAT NOS3 EDN1
4 autosomal dominant polycystic kidney disease 31.1 PKD1 NOS3 EDN1
5 kidney disease 31.1 PKD1 NOS3 EDN1 ADM
6 aortic coarctation 30.9 NOS3 EDN1
7 acquired aneurysmal subarachnoid hemorrhage 12.6
8 aneurysm, intracranial berry, 2 11.8
9 polycystic kidney disease 1 with or without polycystic liver disease 11.5
10 aneurysm, intracranial berry, 5 11.5
11 aneurysm, intracranial berry, 3 11.5
12 aneurysm, intracranial berry, 4 11.5
13 aneurysm, intracranial berry, 6 11.5
14 aneurysm, intracranial berry, 7 11.5
15 aneurysm, intracranial berry, 8 11.5
16 aneurysm, intracranial berry, 9 11.5
17 aneurysm, intracranial berry, 10 11.5
18 aneurysm, intracranial berry, 11 11.5
19 familial cerebral saccular aneurysm 11.5
20 hydrocephalus 11.1
21 congenital hydrocephalus 11.1
22 ocular motor apraxia 10.9
23 ischemia 10.9
24 mandibulofacial dysostosis with alopecia 10.8 EDN3 EDN1
25 platelet aggregation, spontaneous 10.8 SERPINA3 PLAT
26 middle cerebral artery infarction 10.8 S100B PLAT
27 cerebral aneurysms 10.8
28 rare surgical neurologic disease 10.8
29 chronic mountain sickness 10.7 NOS3 EDN1
30 angina pectoris 10.7 PLAT NOS3 EDN1
31 renovascular hypertension 10.7 NOS3 EDN1 ADM
32 acute mountain sickness 10.7 S100B NOS3 EDN1
33 carotid artery thrombosis 10.7 PLAT NOS3
34 sleep apnea 10.7 S100B NOS3 EDN1
35 cutaneous fibrous histiocytoma 10.7 SERPINA3 S100B
36 brachydactyly, type e2 10.7 NOS3 EDN1
37 coronary artery anomaly 10.7 PLAT NOS3 EDN1
38 aneurysm 10.7
39 pulmonary edema 10.7
40 hyperglycemia 10.6
41 pulmonary hypertension 10.6 PLAT NOS3 EDN1 ADM
42 odontogenic myxoma 10.6 SERPINA3 S100B
43 brain injury 10.6
44 eisenmenger syndrome 10.6 PLAT EDN1
45 intracranial hypertension 10.6
46 traumatic brain injury 10.6
47 seizure disorder 10.6
48 hypertension, essential 10.6 PLAT PKD1 NOS3 EDN1 ADM
49 visual epilepsy 10.5
50 granular cell tumor 10.5 SERPINA3 S100B

Graphical network of the top 20 diseases related to Intracranial Berry Aneurysm:



Diseases related to Intracranial Berry Aneurysm

Symptoms & Phenotypes for Intracranial Berry Aneurysm

Drugs & Therapeutics for Intracranial Berry Aneurysm

Drugs for Intracranial Berry Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 143)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
2
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
3
Desflurane Approved Phase 4 57041-67-5 42113
4
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
5
Verapamil Approved Phase 4 52-53-9 2520
6 Psychotropic Drugs Phase 4
7 Hypnotics and Sedatives Phase 4
8 Tranquilizing Agents Phase 4
9 Anti-Anxiety Agents Phase 4
10 Antimanic Agents Phase 4
11 Anesthetics, Inhalation Phase 4
12 Anti-Arrhythmia Agents Phase 4
13 Hematinics Phase 4
14 Epoetin alfa Phase 4 113427-24-0
15
Simvastatin Approved Phase 2, Phase 3 79902-63-9 54454
16
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 3 7487-88-9 24083
17
Ketamine Approved, Vet_approved Phase 2, Phase 3 6740-88-1 3821
18
Nimodipine Approved, Investigational Phase 3 66085-59-4 4497
19
Dexmedetomidine Approved, Vet_approved Phase 3 113775-47-6 68602 5311068
20 Protective Agents Phase 2, Phase 3
21 Neuroprotective Agents Phase 2, Phase 3
22 Cerebrolysin Phase 2, Phase 3
23 Lipid Regulating Agents Phase 2, Phase 3
24 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2, Phase 3
25 Hypolipidemic Agents Phase 2, Phase 3
26 Anticholesteremic Agents Phase 2, Phase 3
27 Antimetabolites Phase 2, Phase 3
28 Tocolytic Agents Phase 3
29 Tin Fluorides Phase 3
30 Neurotransmitter Agents Phase 2, Phase 3
31 Central Nervous System Depressants Phase 2, Phase 3
32 Anesthetics Phase 2, Phase 3
33 Anesthetics, General Phase 2, Phase 3
34 Anesthetics, Intravenous Phase 2, Phase 3
35 Tissue Plasminogen Activator Phase 3
36 Fibrinolytic Agents Phase 3
37 Plasminogen Phase 3
38 Excitatory Amino Acid Antagonists Phase 2, Phase 3
39 Excitatory Amino Acids Phase 2, Phase 3
40 Anesthetics, Dissociative Phase 2, Phase 3
41 Astragalus Phase 2, Phase 3
42 Adrenergic alpha-2 Receptor Agonists Phase 3
43 Adrenergic Agonists Phase 3
44 Analgesics, Non-Narcotic Phase 3
45 Adrenergic alpha-Agonists Phase 3
46 Adrenergic Agents Phase 3
47 Vasoconstrictor Agents Phase 3
48 Lycopene Approved, Investigational Phase 2 502-65-8 53477748
49
Clevidipine Approved, Investigational Phase 2 167221-71-8
50
Minocycline Approved, Investigational Phase 1, Phase 2 10118-90-8 5281021

Interventional clinical trials:

(show top 50) (show all 120)
# Name Status NCT ID Phase Drugs
1 The Role of Statins in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage Unknown status NCT01346748 Phase 4 statin
2 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
3 Gabapentin for Headache in Aneurysmal Subarachnoid Hemorrhage Completed NCT02330094 Phase 4 Gabapentin;Placebo
4 Comparison Of Pharmacological Neuroprotection Provided By PROPOFOL VERSUS DESFLURANE For Long Term Postoperative Cognitive Dysfunction In Patients Undergoing Surgery For Aneurysmal Subarachnoid Hemorrhage Completed NCT02987218 Phase 4 Propofol;Desflurane
5 The Intra-arterial Vasospasm Trial(iVAST)- A Multi-center Randomized Study Recruiting NCT01996436 Phase 4 Nicardipine;Verapamil;Nicardipine + Verapamil + Nitroglycerin
6 A Double Blinded, Placebo Controlled, Pilot Study to Evaluate the Safety of Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
7 Pilot Study of Seizure Prophylaxis With Levetiracetam in Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT01935908 Phase 4 levetiracetam
8 Randomized, Double-blind, Placebo-controlled Pilot Trial to Investigate Safety and Efficacy of Cerebrolysin™ in Patients With Aneurysmal Subarachnoid Hemorrhage Unknown status NCT01787123 Phase 2, Phase 3 Intravenous Cerebrolysin
9 Aneurysmal Subarachnoid Hemorrhage: Red Blood Cell Transfusion and Outcome - A Pilot Randomized Controlled Trial Completed NCT02483351 Phase 2, Phase 3
10 A Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Assess the Efficacy and Safety of Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Surgical Clipping. Completed NCT00558311 Phase 3 clazosentan;placebo
11 Phase 3 Study (Multi-center, Randomized Controlled Clinical Trial) of Intravenous Magnesium Sulfate to Improve Outcome After Aneurysmal Subarachnoid Haemorrhage Completed NCT00124150 Phase 3 Intravenous magnesium sulfate infusion
12 EARLYdrain - Prospective Outcome Study of Early Lumbar Drainage in Aneurysmal Subarachnoid Hemorrhage Completed NCT01258257 Phase 3
13 High-dose Simvastatin for Aneurysmal Subarachnoid Haemorrhage: Is it Better? Completed NCT01077206 Phase 2, Phase 3 Simvastatin
14 Aneurysmal Subarachnoid Hemorrhage - Red Blood Cell Transfusion and Outcome (SAHaRA): A Randomized Controlled Trial Recruiting NCT03309579 Phase 3
15 A Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase 3 Study to Assess the Efficacy and Safety of Clazosentan in Preventing Clinical Deterioration Due to Delayed Cerebral Ischemia (DCI), in Adult Subjects With Aneurysmal Subarachnoid Hemorrhage (aSAH) Recruiting NCT03585270 Phase 3 Clazosentan;Placebo
16 Intraventricular Fibrinolysis Versus External Ventricular Drainage Alone in Aneurysmal Subarachnoid Hemorrhage: a Randomized Controlled Trial. Recruiting NCT03187405 Phase 3 EVD + IVF with Alteplase
17 A Pilot Study of Sub-anesthetic Ketamine Infusion for Neuroprotection After Aneurysmal Subarachnoid Hemorrhage: Effects on White Matter Integrity, Inflammatory Biomarkers and Neurocognitive Outcome Recruiting NCT02636218 Phase 2, Phase 3 Ketamine;0.9% NaCl
18 Efficacy Study of Astragalus Membranaceus on Aneurysmal Subarachnoid Hemorrhage Not yet recruiting NCT03271697 Phase 2, Phase 3 Astragalus Membranaceus;Placebo
19 Effects of Dexmedetomidine on Inflammatory Cytokines in Patients With Aneurysmal Subarachnoid Hemorrhage Terminated NCT01565590 Phase 3 Dexmedetomidine;propofol
20 Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Study Comparing EG-1962 to Standard of Care Oral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage Terminated NCT02790632 Phase 3 EG-1962 (nimodipine microparticles);Enteral Nimodipine
21 Prevention of Secondary Ischemia After Aneurysmal Subarachnoid Hemorrhage With Cerebrospinal Fluid Drainage. A Randomized Controlled Trial Terminated NCT01407614 Phase 2, Phase 3
22 A Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Assess the Efficacy and Safety of Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Endovascular Coiling. Terminated NCT00940095 Phase 3 Clazosentan 5 m/h;Clazosentan 15 mg/h;Placebo
23 Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage Terminated NCT01613235 Phase 3
24 Acute Oral Lycopene Therapy on Cerebral Autoregulation and Delayed Ischaemic Deficits Following Aneurysmal Subarachnoid Haemorrhage (LASH): A Randomized Controlled Trial Unknown status NCT00905931 Phase 2 Lycopene;placebo
25 Intraventricular Tissue Plasminogen Activator in the Management of Aneurysmal Subarachnoid Hemorrhage: a Randomized Controlled Pilot Study Unknown status NCT01098890 Phase 2 Tissue Plasminogen Activator;Placebo
26 Clevidipine in Aneurysmal Subarachnoid Hemorrhage, A Pilot Study Unknown status NCT00978822 Phase 2 Clevidipine butyrate injectable emulsion
27 Clevidipine for Vasospasm After Subarachnoid Hemorrhage Unknown status NCT02011321 Phase 2 clevidipine
28 Minocycline as Neuroprotectant After Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02113176 Phase 1, Phase 2 Minocycline
29 Hypertonic Saline Solution in Aneurysmal Subarachnoid Hemorrhage: A Randomized - Phase II Single Blinded Clinical Trial Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
30 Single Escalating-dose, Open-label Study to Assess the Safety and Effect of SANGUINATE™ Infusion in Patients at Risk of Delayed Cerebral Ischemia (DCI) After Acute Aneurysmal Subarachnoid Hemorrhage (SAH) Completed NCT02323685 Phase 2
31 A Prospective, Multi-center, Open-label, Single-arm, Phase 2 Study to Assess the Efficacy and Safety of Clazosentan in Reversing Angiographically-confirmed Cerebral Vasospasm in Adult Subjects With Aneurysmal Subarachnoid Hemorrhage (aSAH) Treated by Surgical Clipping or Endovascular Coiling Completed NCT02560532 Phase 2 Clazosentan
32 A Phase IIb, Multi-center, International, Double-blind, Randomized, Placebo-controlled, Parallel-group, Dose-finding Study for the Prevention of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage (aSAH) by Intravenous Administration of Clazosentan, a Selective Endothelin A (ETA) Receptor Antagonist Completed NCT00111085 Phase 2 Clazosentan 1 mg/h;Clazosentan 5 mg/h;Clazosentan 15 mg/h;Placebo
33 Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage Completed NCT01095731 Phase 2 Tiopronin;Placebo
34 Balloon Prophylaxis of Aneurysmal Vasospasm Completed NCT00282893 Phase 2
35 Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After subarachNoid Hemorrhage: Phase I/IIa Multicenter, Controlled, Randomized, Open Label, Dose Escalation, Safety, Tolerability, and Pharmacokinectic Study Comparing EG-1962 and Nimodipine in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
36 Effect of Statins on Cerebral Blood Flow After Subarachnoid Hemorrhage Completed NCT00795288 Phase 1, Phase 2 Simvastatin, 80 mg/day for 21 days;placebo
37 A Randomized, Double-Blind, Placebo-Controlled Trial of Simvastatin on Subarachnoid Hemorrhage-Induced Vasospasm Completed NCT00235963 Phase 1, Phase 2 Simvastatin
38 Effect of Red Blood Cell Transfusion on Brain Metabolism in Patients With Subarachnoid Hemorrhage Completed NCT00968227 Phase 1, Phase 2
39 Effects of Systemic Erythropoietin Therapy on Cerebral Autoregulation and Incidence of Delayed Ischemic Deficits in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT00140010 Phase 2 erythropoietin beta
40 A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients With Significant Hemorrhage Burden Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
41 A Phase 1/2a Exploratory Clinical Trial: Induced Suppression of Platelets Activity in Aneurysmal SAH Management (iSPASM) Recruiting NCT03691727 Phase 1, Phase 2 tirofiban hydrochloride (AGGRASTAT®)
42 OSU6162 in the Treatment of Fatigue and Other Neuropsychological Sequelae After Aneurysmal Subarachnoid Hemorrhage - A Double-blind, Randomised, Placebo-controlled Study Recruiting NCT03209830 Phase 2 OSU 6162;Placebo Oral Tablet
43 Subarachnoid Hemorrhage and Soluble Epoxide Hydrolase Inhibition Trial Active, not recruiting NCT03318783 Phase 1, Phase 2 GSK2256294;Placebo
44 Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial Not yet recruiting NCT02875262 Phase 1, Phase 2 Deferoxamine
45 Deferiprone Trial for Subarachnoid Hemorrhage (SAH) Patients Not yet recruiting NCT03754725 Phase 2 Deferiprone pill;placebo
46 Safety and Efficacy of Cervical Sympathetic Block in Patients With Cerebral Vasospasm Following Aneurysmal Subarachnoid Hemorrhage - Pilot Study Terminated NCT00930072 Phase 2 Cervical Sympathetic Block (bupivicaine, clonidine)
47 Milrinone in Addition to Hyperdynamic Therapy in the Treatment of Vasospasm Following Aneurysmal Subarachnoid Hemorrhage Terminated NCT02712788 Phase 2 Milrinone;Placebo
48 Intraventricular Nicardipine for the Treatment of Cerebral Vasospasm: Prospective Pilot Study Terminated NCT01810302 Phase 2 Nicardipine hydrochloride;Preservative-free normal saline
49 Effects of Donepezil on Regional Cerebral Blood Flow Following Aneurysmal Subarachnoid Haemorrhage Terminated NCT02222727 Phase 2 Donepezil
50 Effect of Intraventricular tPA Following Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT01878136 Phase 1, Phase 2 Tissue Plasminogen Activator

Search NIH Clinical Center for Intracranial Berry Aneurysm

Genetic Tests for Intracranial Berry Aneurysm

Anatomical Context for Intracranial Berry Aneurysm

MalaCards organs/tissues related to Intracranial Berry Aneurysm:

41
Brain, Spinal Cord, Endothelial, Pituitary

Publications for Intracranial Berry Aneurysm

Articles related to Intracranial Berry Aneurysm:

(show all 46)
# Title Authors PMID Year
1
Effect of actual age on outcome at discharge in patients by surgical clipping and endovascular coiling for ruptured cerebral aneurysm in Japan. 38
29335886 2018
2
Thrombosis and recanalization of small saccular cerebral aneurysm : two case reports and a suggestion for possible mechanism. 38
25132936 2014
3
Delayed rebleeding of a spontaneously thrombosed aneurysm after subarachnoid hemorrhage. 38
24818049 2014
4
Short-term outcome for saccular cerebral aneurysms treated with the Orbit Galaxy Detachable Coil System. 38
24211142 2014
5
Fluid structural analysis of human cerebral aneurysm using their own wall mechanical properties. 38
24151523 2013
6
Modelling evolution and the evolving mechanical environment of saccular cerebral aneurysms. 38
20496095 2011
7
Early endovascular coiling of posterior communicating artery saccular aneurysm in the setting of Staphylococcus bacteremia: case report and review of the literature. 38
20305472 2010
8
Infraoptic course of both anterior cerebral arteries. 38
20157384 2010
9
Influence of medial collagen organization and axial in situ stretch on saccular cerebral aneurysm growth. 38
19831480 2009
10
Endothelial nitric oxide synthase tagging single nucleotide polymorphisms and recovery from aneurysmal subarachnoid hemorrhage. 9
19419976 2009
11
A theoretical model for fibroblast-controlled growth of saccular cerebral aneurysms. 38
19027028 2009
12
Modeling of saccular aneurysm growth in a human middle cerebral artery. 38
19045519 2008
13
Expressions of PDGF-B and collagen type III in the remodeling of experimental saccular aneurysm in rats. 38
18489818 2008
14
Endothelial nitric oxide synthase polymorphism (-786T->C) and increased risk of angiographic vasospasm after aneurysmal subarachnoid hemorrhage. 9
18309169 2008
15
Role of endothelial nitric oxide synthase gene polymorphisms in predicting aneurysmal subarachnoid hemorrhage in South Indian patients. 9
18688082 2008
16
A model for saccular cerebral aneurysm growth by collagen fibre remodelling. 38
17482213 2007
17
Update on evidence for a genetic predisposition to cerebral vasospasm. 9
17029342 2006
18
Familial aggregation of both aortic and cerebral aneurysms: evidence for a common genetic basis in a subset of families. 38
15792503 2005
19
Vascular corrosion casts mirroring early morphological changes that lead to the formation of saccular cerebral aneurysm: an experimental study in rats. 38
15796390 2005
20
Endothelin-1 levels in plasma and cerebrospinal fluid of patients with cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 9
15967223 2005
21
Mechanisms of disease: roles of nitric oxide and endothelin-1 in delayed cerebral vasospasm produced by aneurysmal subarachnoid hemorrhage. 9
16265315 2004
22
Prevention of symptomatic vasospasm after aneurysmal subarachnoid hemorrhage by intraoperative cisternal fibrinolysis using tissue-type plasminogen activator combined with continuous cisternal drainage. 9
15686175 2004
23
Section on cerebrovascular surgery: Galbraith Award: Endothelial nitric oxide synthase (eNOS) and heme oxygenase-1 (HO-1) gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage (SAH) and post-SAH cerebral vasospasm. 9
15571165 2004
24
Temporal relationship between endothelin-1 concentrations and cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. 9
11340231 2001
25
Increase and uncoupling of adrenomedullin from the natriuretic peptide system in aneurysmal subarachnoid hemorrhage. 9
11213962 2001
26
Adrenomedullin in patients with cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 9
11108778 2000
27
Vertebral arteriovenous fistula associated with neurofibromatosis type I misdiagnosed as a giant aneurysm. 38
20667184 2000
28
[A case of a traumatic anterior cerebral artery aneurysm following the penetration of the skull base by an iron rod]. 38
10396743 1999
29
Intracranial saccular (berry) aneurysm: a brief overview. 38
9225885 1997
30
Endothelin in cerebral vasospasm. Clinical and experimental results. 9
9385564 1997
31
Innovations in aneurysmal subarachnoid hemorrhage: intracisternal t-PA for the prevention of vasospasm. 9
8718759 1996
32
Current Management of Intracranial Subarachnoid Hemorrhage. 38
27681460 1996
33
[Application of alteplase in prevention of cerebral vasospasm and its sequelae in patients after aneurysmal subarachnoid hemorrhage from ruptured cerebral aneurysm]. 9
7566413 1995
34
Endothelin concentrations in patients with aneurysmal subarachnoid hemorrhage. Correlation with cerebral vasospasm, delayed ischemic neurological deficits, and volume of hematoma. 9
7815135 1995
35
A phase II clinical trial of recombinant human tissue-type plasminogen activator against cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 9
7808602 1994
36
Failure of intracisternal tissue plasminogen activator to prevent vasospasm in certain patients with aneurysmal subarachnoid hemorrhage. 9
8052377 1994
37
The role of endothelin-1 in the origin of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. 9
1607979 1992
38
Variability of expression of the orofaciodigital syndrome type I in black females: six cases. 38
2063902 1991
39
Spontaneous saccular cerebral aneurysm in a rat. 38
2068970 1991
40
Angiographic study of induced cerebral aneurysms in primates. 38
2259401 1990
41
Injection-corrosion cast study of the microcirculation of the brain in haemorrhagic and ischaemic disorders. Preliminary investigation. 38
2795187 1989
42
[Microsurgical treatment of 140 cases of intracranial berry aneurysm]. 38
3830621 1985
43
Management of patients with symptomatic extracranial carotid artery disease and incidental intracranial berry aneurysm. 38
3965749 1985
44
[Rupture of intracranial berry aneurysm complicated with hematoma (author's transl)]. 38
7094754 1982
45
Dominant inheritance of intracranial berry aneurysm. 38
6794716 1981
46
An unusual case of intracranial berry aneurysm co--existing with "subclavian steal" syndrome. 38
5661077 1968

Variations for Intracranial Berry Aneurysm

Expression for Intracranial Berry Aneurysm

Search GEO for disease gene expression data for Intracranial Berry Aneurysm.

Pathways for Intracranial Berry Aneurysm

Pathways related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 10.94 PLAT NOS3 EDN1

GO Terms for Intracranial Berry Aneurysm

Biological processes related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of cytosolic calcium ion concentration GO:0007204 9.7 PKD1 EDN1 ADM
2 positive regulation of mitotic nuclear division GO:0045840 9.51 EDN3 EDN1
3 regulation of vasoconstriction GO:0019229 9.49 EDN3 EDN1
4 vasoconstriction GO:0042310 9.48 EDN3 EDN1
5 inositol phosphate-mediated signaling GO:0048016 9.46 EDN3 EDN1
6 positive regulation of hormone secretion GO:0046887 9.43 EDN3 EDN1
7 artery smooth muscle contraction GO:0014824 9.4 EDN3 EDN1
8 response to fluid shear stress GO:0034405 9.37 PKD1 NOS3
9 positive regulation of heart rate GO:0010460 9.33 EDN3 EDN1 ADM
10 vein smooth muscle contraction GO:0014826 9.32 EDN3 EDN1
11 peptide hormone secretion GO:0030072 9.26 EDN3 EDN1
12 regulation of blood vessel size GO:0050880 9.13 NOS3 EDN3 EDN1
13 regulation of systemic arterial blood pressure by endothelin GO:0003100 8.8 NOS3 EDN3 EDN1

Molecular functions related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 signaling receptor binding GO:0005102 9.35 S100B PLAT EDN3 EDN1 ADM
2 hormone activity GO:0005179 9.33 EDN3 EDN1 ADM
3 endothelin B receptor binding GO:0031708 8.62 EDN3 EDN1

Sources for Intracranial Berry Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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