MCID: INT260
MIFTS: 39

Intracranial Berry Aneurysm

Categories: Cardiovascular diseases, Genetic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Intracranial Berry Aneurysm

MalaCards integrated aliases for Intracranial Berry Aneurysm:

Name: Intracranial Berry Aneurysm 12 15
Familial Aneurysmal Subarachnoid Hemorrhage 12
Familial Intracranial Saccular Aneurysm 12
Aneurysmal Subarachnoid Hemorrhage 15
Aneurysm, Intracranial Berry, 1 71
Aneurysm, Intracranial Berry 74
Saccular Cerebral Aneurysm 12
Familial Berry Aneurysm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0060228
ICD10 32 I60.7
UMLS 71 C1862932

Summaries for Intracranial Berry Aneurysm

Disease Ontology : 12 An intracranial aneurysm with a characteristic rounded shape; the most common form of cerebral aneurysm.

MalaCards based summary : Intracranial Berry Aneurysm, also known as familial aneurysmal subarachnoid hemorrhage, is related to ischemia and pulmonary edema. An important gene associated with Intracranial Berry Aneurysm is ANIB1 (Aneurysm, Intracranial Berry 1), and among its related pathways/superpathways are Oxytocin signaling pathway and HIF-1 signaling pathway. The drugs Propofol and Gabapentin have been mentioned in the context of this disorder. Affiliated tissues include brain, spinal cord and endothelial.

Wikipedia : 74 Intracranial aneurysm, also known as brain aneurysm, is a cerebrovascular disorder in which weakness in... more...

Related Diseases for Intracranial Berry Aneurysm

Diseases in the Intracranial Berry Aneurysm family:

Aneurysm, Intracranial Berry, 1 Aneurysm, Intracranial Berry, 5
Aneurysm, Intracranial Berry, 2 Aneurysm, Intracranial Berry, 3
Aneurysm, Intracranial Berry, 4 Aneurysm, Intracranial Berry, 6
Aneurysm, Intracranial Berry, 7 Aneurysm, Intracranial Berry, 8
Aneurysm, Intracranial Berry, 9 Aneurysm, Intracranial Berry, 10
Aneurysm, Intracranial Berry, 11 Aneurysm, Intracranial Berry, 12

Diseases related to Intracranial Berry Aneurysm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 295)
# Related Disease Score Top Affiliating Genes
1 ischemia 32.3 PLAT NOS3 HMOX1 EDN1
2 pulmonary edema 32.0 NOS3 HMOX1 EDN1
3 renal hypertension 31.4 NOS3 EDN1 ADM
4 cardiogenic shock 31.3 PLAT ADM
5 kidney disease 31.2 SERPINA3 PKD1 NOS3 HMOX1 EDN1 ADM
6 limb ischemia 31.1 PLAT NOS3 EDN1
7 intracranial aneurysm 31.0 PLAT PKD1 NOS3
8 myocardial infarction 30.9 SERPINA3 PLAT NOS3 HMOX1 EDN1 ADM
9 sexual disorder 30.9 SERPINA3 NOS3 EDN1
10 pre-eclampsia 30.8 PLAT NOS3 HMOX1 EDN1 ADM
11 cardiovascular system disease 30.8 SERPINA3 PLAT NOS3 HMOX1 EDN1 ADM
12 hellp syndrome 30.8 PLAT EDN1 ADM
13 coronary artery vasospasm 30.7 NOS3 EDN1
14 stroke, ischemic 30.7 SERPINA3 PLAT NOS3 ADM
15 aneurysm, intracranial berry, 12 12.9
16 acquired aneurysmal subarachnoid hemorrhage 12.6
17 aneurysm, intracranial berry, 2 11.8
18 polycystic kidney disease 1 with or without polycystic liver disease 11.5
19 aneurysm, intracranial berry, 5 11.5
20 aneurysm, intracranial berry, 3 11.5
21 aneurysm, intracranial berry, 4 11.5
22 aneurysm, intracranial berry, 6 11.5
23 aneurysm, intracranial berry, 7 11.5
24 aneurysm, intracranial berry, 8 11.5
25 aneurysm, intracranial berry, 9 11.5
26 aneurysm, intracranial berry, 10 11.5
27 aneurysm, intracranial berry, 11 11.5
28 familial cerebral saccular aneurysm 11.5
29 hydrocephalus 11.1
30 ocular motor apraxia 10.9
31 cerebral aneurysms 10.8
32 aneurysm 10.7
33 angina pectoris 10.7 PLAT NOS3 EDN1
34 acute chest syndrome 10.7 NOS3 HMOX1 EDN1
35 hepatopulmonary syndrome 10.7 NOS3 HMOX1 EDN1
36 diabetic angiopathy 10.7 NOS3 EDN1 ADM
37 vein disease 10.7 SERPINA3 PLAT EDN1
38 platelet aggregation, spontaneous 10.7 SERPINA3 PLAT
39 pulmonary emphysema 10.7 SERPINA3 NOS3 HMOX1
40 renovascular hypertension 10.7 PKD1 NOS3 HMOX1 EDN1 ADM
41 cerebral arterial disease 10.7 SERPINA3 PKD1 NOS3 EDN1 ECI1
42 idiopathic edema 10.7 EDN1 ADM
43 eisenmenger syndrome 10.6 PLAT EDN1
44 atherosclerosis susceptibility 10.6 PLAT NOS3 HMOX1 EDN1
45 peripheral artery disease 10.6 NOS3 HMOX1 EDN1
46 orthostatic intolerance 10.6 PKD1 NOS3 EDN1
47 chronic mountain sickness 10.6 NOS3 EDN1
48 lipoprotein quantitative trait locus 10.6 PLAT NOS3 EDN1 ADM
49 acute myocardial infarction 10.6 SERPINA3 PLAT EDN1 ADM
50 pulmonary hypertension 10.6 PLAT NOS3 HMOX1 EDN1 ADM

Graphical network of the top 20 diseases related to Intracranial Berry Aneurysm:



Diseases related to Intracranial Berry Aneurysm

Symptoms & Phenotypes for Intracranial Berry Aneurysm

Drugs & Therapeutics for Intracranial Berry Aneurysm

Drugs for Intracranial Berry Aneurysm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 139)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Propofol Approved, Investigational, Vet_approved Phase 4 2078-54-8 4943
2
Gabapentin Approved, Investigational Phase 4 60142-96-3 3446
3
Desflurane Approved Phase 4 57041-67-5 42113
4
Verapamil Approved Phase 4 52-53-9 2520
5
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
6
Cilostazol Approved, Investigational Phase 4 73963-72-1 2754
7 Psychotropic Drugs Phase 4
8 Hypnotics and Sedatives Phase 4
9 Anti-Anxiety Agents Phase 4
10 Anesthetics, Inhalation Phase 4
11 Fibrinolytic Agents Phase 4
12 Anti-Arrhythmia Agents Phase 4
13 Anti-Asthmatic Agents Phase 4
14 Neuroprotective Agents Phase 4
15 Bronchodilator Agents Phase 4
16 Hematinics Phase 4
17 Epoetin alfa Phase 4 113427-24-0
18
Simvastatin Approved Phase 2, Phase 3 79902-63-9 54454
19
Magnesium Sulfate Approved, Investigational, Vet_approved Phase 3 7487-88-9 24083
20
Ketamine Approved, Vet_approved Phase 2, Phase 3 6740-88-1 3821
21
Dexmedetomidine Approved, Vet_approved Phase 3 113775-47-6 5311068 68602
22 Hydroxymethylglutaryl-CoA Reductase Inhibitors Phase 2, Phase 3
23 Hypolipidemic Agents Phase 2, Phase 3
24 Anticholesteremic Agents Phase 2, Phase 3
25 Lipid Regulating Agents Phase 2, Phase 3
26 Antimetabolites Phase 2, Phase 3
27 Tocolytic Agents Phase 3
28 Tin Fluorides Phase 3
29 Cerebrolysin Phase 2, Phase 3
30 Anesthetics Phase 2, Phase 3
31 Anesthetics, General Phase 2, Phase 3
32 Anesthetics, Intravenous Phase 2, Phase 3
33 Tissue Plasminogen Activator Phase 3
34 Plasminogen Phase 3
35 Excitatory Amino Acid Antagonists Phase 2, Phase 3
36 Anesthetics, Dissociative Phase 2, Phase 3
37 Astragalus Phase 2, Phase 3
38 Adrenergic alpha-Agonists Phase 3
39 Adrenergic Agents Phase 3
40 Analgesics, Non-Narcotic Phase 3
41 Adrenergic Agonists Phase 3
42 Vasoconstrictor Agents Phase 3
43
Deferoxamine Approved, Investigational Phase 1, Phase 2 70-51-9 2973
44 Lycopene Approved, Investigational Phase 2 502-65-8 53477748
45
Clevidipine Approved, Investigational Phase 2 167221-71-8
46
tannic acid Approved Phase 1, Phase 2 1401-55-4
47
Benzocaine Approved, Investigational Phase 1, Phase 2 94-09-7, 1994-09-7 2337
48
Minocycline Approved, Investigational Phase 1, Phase 2 10118-90-8 5281021
49
acetic acid Approved Phase 2 64-19-7 176
50
Heparin Approved, Investigational Phase 2 9005-49-6 46507594 772

Interventional clinical trials:

(show top 50) (show all 131)
# Name Status NCT ID Phase Drugs
1 The Role of Statins in Preventing Cerebral Vasospasm Secondary to Subarachnoid Hemorrhage Unknown status NCT01346748 Phase 4 statin
2 Delayed Vasospasm After Aneurysm With the Standardization Treatment of Traditional Chinese Medicine Unknown status NCT01840761 Phase 4 herbal drug;placebo
3 Gabapentin for Headache in Aneurysmal Subarachnoid Hemorrhage Completed NCT02330094 Phase 4 Gabapentin;Placebo
4 Comparison Of Pharmacological Neuroprotection Provided By PROPOFOL VERSUS DESFLURANE For Long Term Postoperative Cognitive Dysfunction In Patients Undergoing Surgery For Aneurysmal Subarachnoid Hemorrhage Completed NCT02987218 Phase 4 Propofol;Desflurane
5 The Intra-arterial Vasospasm Trial(iVAST)- A Multi-center Randomized Study Recruiting NCT01996436 Phase 4 Nicardipine;Verapamil;Nicardipine + Verapamil + Nitroglycerin
6 Efficacy and Safety of Cilostazol-Nimodipine Combined Therapy on Delayed Cerebral Ischemia After Aneurysmal Subarachnoid Hemorrhage (aSAH): A Prospective, Randomized, Double-Blinded, Placebo-Controlled Trial Recruiting NCT04148105 Phase 4 Cilostazol 100 MG
7 A Double Blinded, Placebo Controlled, Pilot Study to Evaluate the Safety of Treating Patients With Aneurysmal SubArachnoid Hemorrhage (SAH) With Epoetin Alfa Terminated NCT00626574 Phase 4 Epoetin alfa;Saline
8 Pilot Study of Seizure Prophylaxis With Levetiracetam in Aneurysmal Subarachnoid Hemorrhage Withdrawn NCT01935908 Phase 4 levetiracetam
9 Aneurysmal Subarachnoid Hemorrhage: Red Blood Cell Transfusion and Outcome - A Pilot Randomized Controlled Trial Completed NCT02483351 Phase 2, Phase 3
10 A Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Assess the Efficacy and Safety of Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Surgical Clipping. Completed NCT00558311 Phase 3 Clazosentan;Placebo
11 Phase 3 Study (Multi-center, Randomized Controlled Clinical Trial) of Intravenous Magnesium Sulfate to Improve Outcome After Aneurysmal Subarachnoid Haemorrhage Completed NCT00124150 Phase 3 Intravenous magnesium sulfate infusion
12 EARLYdrain - Prospective Outcome Study of Early Lumbar Drainage in Aneurysmal Subarachnoid Hemorrhage Completed NCT01258257 Phase 3
13 Randomized, Double-blind, Placebo-controlled Pilot Trial to Investigate Safety and Efficacy of Cerebrolysin™ in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT01787123 Phase 2, Phase 3 Intravenous Cerebrolysin;Normal Saline
14 High-dose Simvastatin for Aneurysmal Subarachnoid Haemorrhage: Is it Better? Completed NCT01077206 Phase 2, Phase 3 Simvastatin
15 Aneurysmal Subarachnoid Hemorrhage - Red Blood Cell Transfusion and Outcome (SAHaRA): A Randomized Controlled Trial Recruiting NCT03309579 Phase 3
16 Intraventricular Fibrinolysis Versus External Ventricular Drainage Alone in Aneurysmal Subarachnoid Hemorrhage: a Randomized Controlled Trial. Recruiting NCT03187405 Phase 3 EVD + IVF with Alteplase
17 A Pilot Study of Sub-anesthetic Ketamine Infusion for Neuroprotection After Aneurysmal Subarachnoid Hemorrhage: Effects on White Matter Integrity, Inflammatory Biomarkers and Neurocognitive Outcome Recruiting NCT02636218 Phase 2, Phase 3 Ketamine;0.9% NaCl
18 A Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group, Phase 3 Study to Assess the Efficacy and Safety of Clazosentan in Preventing Clinical Deterioration Due to Delayed Cerebral Ischemia (DCI), in Adult Subjects With Aneurysmal Subarachnoid Hemorrhage (aSAH) Active, not recruiting NCT03585270 Phase 3 Clazosentan;Placebo
19 Efficacy Study of Astragalus Membranaceus on Aneurysmal Subarachnoid Hemorrhage Not yet recruiting NCT03271697 Phase 2, Phase 3 Astragalus Membranaceus;Placebo
20 Effects of Dexmedetomidine on Inflammatory Cytokines in Patients With Aneurysmal Subarachnoid Hemorrhage Terminated NCT01565590 Phase 3 Dexmedetomidine;propofol
21 Phase 3, Multicenter, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group, Efficacy and Safety Study Comparing EG-1962 to Standard of Care Oral Nimodipine in Adults With Aneurysmal Subarachnoid Hemorrhage Terminated NCT02790632 Phase 3 EG-1962 (nimodipine microparticles);Enteral Nimodipine
22 Prevention of Secondary Ischemia After Aneurysmal Subarachnoid Hemorrhage With Cerebrospinal Fluid Drainage. A Randomized Controlled Trial Terminated NCT01407614 Phase 2, Phase 3
23 A Prospective, Multi-center, Double-blind, Randomized, Placebo-controlled, Parallel-group Study to Assess the Efficacy and Safety of Clazosentan in Reducing Vasospasm-related Morbidity and All-cause Mortality in Adult Patients With Aneurysmal Subarachnoid Hemorrhage Treated by Endovascular Coiling. Terminated NCT00940095 Phase 3 Clazosentan 5 m/h;Clazosentan 15 mg/h;Placebo
24 Induced Hypertension for Treatment of Delayed Cerebral Ischaemia After Aneurysmal Subarachnoid Haemorrhage Terminated NCT01613235 Phase 3
25 Deferoxamine in Aneurysmal Subarachnoid Hemorrhage Trial Unknown status NCT02875262 Phase 1, Phase 2 Deferoxamine
26 Acute Oral Lycopene Therapy on Cerebral Autoregulation and Delayed Ischaemic Deficits Following Aneurysmal Subarachnoid Haemorrhage (LASH): A Randomized Controlled Trial Unknown status NCT00905931 Phase 2 Lycopene;placebo
27 Clevidipine in Aneurysmal Subarachnoid Hemorrhage, A Pilot Study Unknown status NCT00978822 Phase 2 Clevidipine butyrate injectable emulsion
28 Intraventricular Tissue Plasminogen Activator in the Management of Aneurysmal Subarachnoid Hemorrhage: a Randomized Controlled Pilot Study Unknown status NCT01098890 Phase 2 Tissue Plasminogen Activator;Placebo
29 Clevidipine for Vasospasm After Subarachnoid Hemorrhage Unknown status NCT02011321 Phase 2 clevidipine
30 Hypertonic Saline Solution in Aneurysmal Subarachnoid Hemorrhage: A Randomized - Phase II Single Blinded Clinical Trial Unknown status NCT02432157 Phase 1, Phase 2 HTS 3%;Standard fluid management
31 Minocycline as Neuroprotectant After Aneurysmal Subarachnoid Hemorrhage Unknown status NCT02113176 Phase 1, Phase 2 Minocycline
32 Single Escalating-dose, Open-label Study to Assess the Safety and Effect of SANGUINATE™ Infusion in Patients at Risk of Delayed Cerebral Ischemia (DCI) After Acute Aneurysmal Subarachnoid Hemorrhage (SAH) Completed NCT02323685 Phase 2
33 A Prospective, Multi-center, Open-label, Single-arm, Phase 2 Study to Assess the Efficacy and Safety of Clazosentan in Reversing Angiographically-confirmed Cerebral Vasospasm in Adult Subjects With Aneurysmal Subarachnoid Hemorrhage (aSAH) Treated by Surgical Clipping or Endovascular Coiling Completed NCT02560532 Phase 2 Clazosentan
34 A Phase IIb, Multi-center, International, Double-blind, Randomized, Placebo-controlled, Parallel-group, Dose-finding Study for the Prevention of Cerebral Vasospasm After Aneurysmal Subarachnoid Hemorrhage (aSAH) by Intravenous Administration of Clazosentan, a Selective Endothelin A (ETA) Receptor Antagonist Completed NCT00111085 Phase 2 Clazosentan 1 mg/h;Clazosentan 5 mg/h;Clazosentan 15 mg/h;Placebo
35 Phase II Study of the Effects of Tiopronin on 3-Aminopropanal Level & Neurologic Outcome After Aneurysmal Subarachnoid Hemorrhage Completed NCT01095731 Phase 2 Tiopronin;Placebo
36 Nimodipine Microparticles to Enhance Recovery While Reducing TOxicity After subarachNoid Hemorrhage: Phase I/IIa Multicenter, Controlled, Randomized, Open Label, Dose Escalation, Safety, Tolerability, and Pharmacokinectic Study Comparing EG-1962 and Nimodipine in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT01893190 Phase 1, Phase 2 Nimodipine;Nimodipine Microparticles
37 Balloon Prophylaxis of Aneurysmal Vasospasm Completed NCT00282893 Phase 2
38 Effect of Statins on Cerebral Blood Flow After Subarachnoid Hemorrhage Completed NCT00795288 Phase 1, Phase 2 Simvastatin, 80 mg/day for 21 days;placebo
39 Intraventricular Rt-PA Pharmacokinetic and Pharmacodynamic Study Completed NCT00029315 Phase 2 Recombinant Tissue Plasminogen Activator (rt-PA)
40 OSU6162 in the Treatment of Fatigue and Other Neuropsychological Sequelae After Aneurysmal Subarachnoid Hemorrhage - A Double-blind, Randomised, Placebo-controlled Study Completed NCT03209830 Phase 2 OSU 6162;Placebo Oral Tablet
41 A Randomized, Double-Blind, Placebo-Controlled Trial of Simvastatin on Subarachnoid Hemorrhage-Induced Vasospasm Completed NCT00235963 Phase 1, Phase 2 Simvastatin
42 Effect of Red Blood Cell Transfusion on Brain Metabolism in Patients With Subarachnoid Hemorrhage Completed NCT00968227 Phase 1, Phase 2
43 Effects of Systemic Erythropoietin Therapy on Cerebral Autoregulation and Incidence of Delayed Ischemic Deficits in Patients With Aneurysmal Subarachnoid Hemorrhage Completed NCT00140010 Phase 2 erythropoietin beta
44 A Blind-adjudication Multi-center Phase II Randomized Clinical Trial of Continuous Low-dose Intravenous Heparin Therapy in Coiled Low-grade Aneurysmal Subarachnoid Hemorrhage Patients With Significant Hemorrhage Burden Recruiting NCT02501434 Phase 2 Continuous Low-Dose IV Unfractionated Heparin Infusion
45 A Phase 1/2a Exploratory Clinical Trial: Induced Suppression of Platelets Activity in Aneurysmal SAH Management (iSPASM) Recruiting NCT03691727 Phase 1, Phase 2 tirofiban hydrochloride (AGGRASTAT®)
46 A Phase IIb: Randomised, Single-Blind, Safety, Tolerability, Efficacy and Pharmacokinetic Study of NicaPlant® in Aneurysmal Subarachnoid Haemorrhage Patients Undergoing Aneurysm Clipping Recruiting NCT04269408 Phase 2 Nicardipine
47 Subarachnoid Hemorrhage and Soluble Epoxide Hydrolase Inhibition Trial Active, not recruiting NCT03318783 Phase 1, Phase 2 GSK2256294;Placebo
48 Deferiprone Trial for Subarachnoid Hemorrhage (SAH) Patients Not yet recruiting NCT03754725 Phase 2 Deferiprone pill;placebo
49 Efficacy of 10 Days Intravenous Milrinone Treatment to Optimize Cerebral Hemodynamic and Prevent Delayed Cerebral Ischemia (DCI) in Patients With Severe Subarachnoid Hemorrhage Due to Intracranial Aneurysm Rupture Not yet recruiting NCT04282629 Phase 2 Milrinone Injection
50 Stellate Ganglion Block as Adjuvant Therapy to ca Channel Blocker in Prevention of Cerebrovascular Spasm in Traumatic Subarachnoid Hemorrhage Not yet recruiting NCT04100824 Phase 2 Nimodipine

Search NIH Clinical Center for Intracranial Berry Aneurysm

Genetic Tests for Intracranial Berry Aneurysm

Anatomical Context for Intracranial Berry Aneurysm

MalaCards organs/tissues related to Intracranial Berry Aneurysm:

40
Brain, Spinal Cord, Endothelial, Pituitary

Publications for Intracranial Berry Aneurysm

Articles related to Intracranial Berry Aneurysm:

(show all 47)
# Title Authors PMID Year
1
Rare Spontaneous Disappearance of Intracranial Aneurysm. 61
31765869 2020
2
Effect of actual age on outcome at discharge in patients by surgical clipping and endovascular coiling for ruptured cerebral aneurysm in Japan. 61
29335886 2018
3
Thrombosis and recanalization of small saccular cerebral aneurysm : two case reports and a suggestion for possible mechanism. 61
25132936 2014
4
Delayed rebleeding of a spontaneously thrombosed aneurysm after subarachnoid hemorrhage. 61
24818049 2014
5
Short-term outcome for saccular cerebral aneurysms treated with the Orbit Galaxy Detachable Coil System. 61
24211142 2014
6
Fluid structural analysis of human cerebral aneurysm using their own wall mechanical properties. 61
24151523 2013
7
Modelling evolution and the evolving mechanical environment of saccular cerebral aneurysms. 61
20496095 2011
8
Early endovascular coiling of posterior communicating artery saccular aneurysm in the setting of Staphylococcus bacteremia: case report and review of the literature. 61
20305472 2010
9
Infraoptic course of both anterior cerebral arteries. 61
20157384 2010
10
Influence of medial collagen organization and axial in situ stretch on saccular cerebral aneurysm growth. 61
19831480 2009
11
Endothelial nitric oxide synthase tagging single nucleotide polymorphisms and recovery from aneurysmal subarachnoid hemorrhage. 54
19419976 2009
12
A theoretical model for fibroblast-controlled growth of saccular cerebral aneurysms. 61
19027028 2009
13
Modeling of saccular aneurysm growth in a human middle cerebral artery. 61
19045519 2008
14
Expressions of PDGF-B and collagen type III in the remodeling of experimental saccular aneurysm in rats. 61
18489818 2008
15
Endothelial nitric oxide synthase polymorphism (-786T->C) and increased risk of angiographic vasospasm after aneurysmal subarachnoid hemorrhage. 54
18309169 2008
16
Role of endothelial nitric oxide synthase gene polymorphisms in predicting aneurysmal subarachnoid hemorrhage in South Indian patients. 54
18688082 2008
17
A model for saccular cerebral aneurysm growth by collagen fibre remodelling. 61
17482213 2007
18
Update on evidence for a genetic predisposition to cerebral vasospasm. 54
17029342 2006
19
Familial aggregation of both aortic and cerebral aneurysms: evidence for a common genetic basis in a subset of families. 61
15792503 2005
20
Vascular corrosion casts mirroring early morphological changes that lead to the formation of saccular cerebral aneurysm: an experimental study in rats. 61
15796390 2005
21
Endothelin-1 levels in plasma and cerebrospinal fluid of patients with cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 54
15967223 2005
22
Mechanisms of disease: roles of nitric oxide and endothelin-1 in delayed cerebral vasospasm produced by aneurysmal subarachnoid hemorrhage. 54
16265315 2004
23
Prevention of symptomatic vasospasm after aneurysmal subarachnoid hemorrhage by intraoperative cisternal fibrinolysis using tissue-type plasminogen activator combined with continuous cisternal drainage. 54
15686175 2004
24
Section on cerebrovascular surgery: Galbraith Award: Endothelial nitric oxide synthase (eNOS) and heme oxygenase-1 (HO-1) gene polymorphisms predict susceptibility to aneurysmal subarachnoid hemorrhage (SAH) and post-SAH cerebral vasospasm. 54
15571165 2004
25
Temporal relationship between endothelin-1 concentrations and cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. 54
11340231 2001
26
Increase and uncoupling of adrenomedullin from the natriuretic peptide system in aneurysmal subarachnoid hemorrhage. 54
11213962 2001
27
Adrenomedullin in patients with cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 54
11108778 2000
28
Vertebral arteriovenous fistula associated with neurofibromatosis type I misdiagnosed as a giant aneurysm. 61
20667184 2000
29
[A case of a traumatic anterior cerebral artery aneurysm following the penetration of the skull base by an iron rod]. 61
10396743 1999
30
Intracranial saccular (berry) aneurysm: a brief overview. 61
9225885 1997
31
Endothelin in cerebral vasospasm. Clinical and experimental results. 54
9385564 1997
32
Innovations in aneurysmal subarachnoid hemorrhage: intracisternal t-PA for the prevention of vasospasm. 54
8718759 1996
33
Current Management of Intracranial Subarachnoid Hemorrhage. 61
27681460 1996
34
[Application of alteplase in prevention of cerebral vasospasm and its sequelae in patients after aneurysmal subarachnoid hemorrhage from ruptured cerebral aneurysm]. 54
7566413 1995
35
Endothelin concentrations in patients with aneurysmal subarachnoid hemorrhage. Correlation with cerebral vasospasm, delayed ischemic neurological deficits, and volume of hematoma. 54
7815135 1995
36
A phase II clinical trial of recombinant human tissue-type plasminogen activator against cerebral vasospasm after aneurysmal subarachnoid hemorrhage. 54
7808602 1994
37
Failure of intracisternal tissue plasminogen activator to prevent vasospasm in certain patients with aneurysmal subarachnoid hemorrhage. 54
8052377 1994
38
The role of endothelin-1 in the origin of cerebral vasospasm in patients with aneurysmal subarachnoid hemorrhage. 54
1607979 1992
39
Variability of expression of the orofaciodigital syndrome type I in black females: six cases. 61
2063902 1991
40
Spontaneous saccular cerebral aneurysm in a rat. 61
2068970 1991
41
Angiographic study of induced cerebral aneurysms in primates. 61
2259401 1990
42
Injection-corrosion cast study of the microcirculation of the brain in haemorrhagic and ischaemic disorders. Preliminary investigation. 61
2795187 1989
43
[Microsurgical treatment of 140 cases of intracranial berry aneurysm]. 61
3830621 1985
44
Management of patients with symptomatic extracranial carotid artery disease and incidental intracranial berry aneurysm. 61
3965749 1985
45
[Rupture of intracranial berry aneurysm complicated with hematoma (author's transl)]. 61
7094754 1982
46
Dominant inheritance of intracranial berry aneurysm. 61
6794716 1981
47
An unusual case of intracranial berry aneurysm co--existing with "subclavian steal" syndrome. 61
5661077 1968

Variations for Intracranial Berry Aneurysm

Expression for Intracranial Berry Aneurysm

Search GEO for disease gene expression data for Intracranial Berry Aneurysm.

Pathways for Intracranial Berry Aneurysm

Pathways related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.92 NOS3 EDN3 EDN1 ADM
2 11.47 NOS3 HMOX1 EDN1
3 11.07 PLAT NOS3 HMOX1 EDN1
4 10.94 HMOX1 EDN1 ADM

GO Terms for Intracranial Berry Aneurysm

Cellular components related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell GO:0005623 9.1 PKD1 NOS3 HMOX1 EDN3 EDN1 ADM

Biological processes related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 response to hypoxia GO:0001666 9.67 PLAT HMOX1 EDN1 ADM
2 regulation of blood pressure GO:0008217 9.58 NOS3 HMOX1 EDN1
3 positive regulation of blood vessel diameter GO:0097755 9.54 HMOX1 ADM
4 regulation of vasoconstriction GO:0019229 9.52 EDN3 EDN1
5 vasoconstriction GO:0042310 9.51 EDN3 EDN1
6 inositol phosphate-mediated signaling GO:0048016 9.49 EDN3 EDN1
7 positive regulation of hormone secretion GO:0046887 9.48 EDN3 EDN1
8 artery smooth muscle contraction GO:0014824 9.46 EDN3 EDN1
9 response to fluid shear stress GO:0034405 9.43 PKD1 NOS3
10 peptide hormone secretion GO:0030072 9.32 EDN3 EDN1
11 vein smooth muscle contraction GO:0014826 9.26 EDN3 EDN1
12 smooth muscle hyperplasia GO:0014806 9.16 NOS3 HMOX1
13 positive regulation of heart rate GO:0010460 9.13 EDN3 EDN1 ADM
14 regulation of systemic arterial blood pressure by endothelin GO:0003100 8.8 NOS3 EDN3 EDN1

Molecular functions related to Intracranial Berry Aneurysm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 9.13 EDN3 EDN1 ADM
2 endothelin B receptor binding GO:0031708 8.62 EDN3 EDN1

Sources for Intracranial Berry Aneurysm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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