MCID: INT110
MIFTS: 19

Intracranial Cysts

Categories: Neuronal diseases

Aliases & Classifications for Intracranial Cysts

MalaCards integrated aliases for Intracranial Cysts:

Name: Intracranial Cysts 53

Classifications:



Summaries for Intracranial Cysts

NINDS : 53 Arachnoid cysts are cerebrospinal fluid-filled sacs that are located between the brain or spinal cord and the arachnoid membrane, one of the three membranes that cover the brain and spinal cord.   Primary arachnoid cysts are present at birth and are the result of developmental abnormalities in the brain and spinal cord that arise during the early weeks of gestation.  Secondary arachnoid cysts are not as common as primary cysts and develop as a result of head injury, meningitis, or tumors, or as a complication of brain surgery.  The majority of arachnoid cysts form outside the temporal lobe of the brain in an area of the skull known as the middle cranial fossa.  Arachnoid cysts involving the spinal cord are rarer.  The location and size of the cyst determine the symptoms and when those symptoms begin.  Most individuals with arachnoid cysts develop symptoms before the age of 20, and especially during the first year of life, but some people with arachnoid cysts never have symptoms.  Males are four times more likely to have arachnoid cysts than females.  Typical symptoms of an arachnoid cyst around the brain include headache, nausea and vomiting, seizures, hearing and visual disturbances, vertigo, and difficulties with balance and walking.  Arachnoid cysts around the spinal cord compress the spinal cord or nerve roots and cause symptoms such as progressive back and leg pain and tingling or numbness in the legs or arms.  Diagnosis usually involves a brain scan or spine scan using diffusion-weighted MRI (magnetic resonance imaging) which helps distinguish fluid-filled arachnoid cysts from other types of cysts.

MalaCards based summary : Intracranial Cysts is related to hydrocephalus and obstructive hydrocephalus. An important gene associated with Intracranial Cysts is ENO2 (Enolase 2), and among its related pathways/superpathways are Neuroscience and Signaling by ERBB4. Affiliated tissues include brain, spinal cord and temporal lobe.

Related Diseases for Intracranial Cysts

Diseases related to Intracranial Cysts via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 198)
# Related Disease Score Top Affiliating Genes
1 hydrocephalus 30.0 S100B GFAP ENO2
2 obstructive hydrocephalus 29.9 GFAP ENO2
3 head injury 29.8 S100B ENO2
4 cystic teratoma 29.6 GFAP ENO2
5 benign teratoma 29.4 MUC1 ENO2
6 subependymal giant cell astrocytoma 29.3 S100B GFAP ENO2
7 aicardi syndrome 11.0
8 arachnoid cysts, intracranial 10.3
9 bednar tumor 10.1 S100B ENO2
10 akinetic mutism 10.1 S100B ENO2
11 post-cardiac arrest syndrome 10.1 S100B ENO2
12 cardiac arrest 10.1 S100B ENO2
13 middle cerebral artery infarction 10.1 S100B ENO2
14 subleukemic leukemia 10.1 S100B ENO2
15 asphyxia neonatorum 10.1 S100B ENO2
16 acute mountain sickness 10.1 S100B ENO2
17 spondylosis 10.0 S100B ENO2
18 papillary ependymoma 10.0 S100B GFAP
19 primitive neuroectodermal tumor of the cervix uteri 10.0 GFAP ENO2
20 cerebral neuroblastoma 10.0 GFAP ENO2
21 cerebellopontine angle primitive neuroectodermal tumor 10.0 GFAP ENO2
22 olfactory neuroblastoma 10.0 S100B ENO2
23 subependymoma 10.0 GFAP ENO2
24 angiocentric glioma 10.0 S100B GFAP
25 spinal cord oligodendroglioma 10.0 GFAP ENO2
26 endobronchial leiomyoma 10.0 GFAP ENO2
27 rhabdoid meningioma 10.0 GFAP ENO2
28 cerebrovascular benign neoplasm 10.0 GFAP ENO2
29 gemistocytic astrocytoma 10.0 S100B GFAP
30 cerebellum cancer 10.0 GFAP ENO2
31 olfactory nerve neoplasm 10.0 GFAP ENO2
32 cranial nerve malignant neoplasm 10.0 GFAP ENO2
33 ganglioneuroblastoma 10.0 S100B ENO2
34 cerebellar medulloblastoma 10.0 GFAP ENO2
35 dandy-walker syndrome 10.0
36 pineal gland cancer 10.0 GFAP ENO2
37 gangliocytoma 10.0 GFAP ENO2
38 central nervous system primitive neuroectodermal neoplasm 10.0 GFAP ENO2
39 cranial nerve neoplasm 10.0 GFAP ENO2
40 ependymoblastoma 10.0 GFAP ENO2
41 melanotic neuroectodermal tumor 10.0 GFAP ENO2
42 spinal cancer 10.0 GFAP ENO2
43 supratentorial primitive neuroectodermal tumor 10.0 S100B GFAP
44 cerebral ventricle cancer 10.0 GFAP ENO2
45 clear cell sarcoma 10.0 S100B ENO2
46 cerebrum cancer 10.0 GFAP ENO2
47 fibrous histiocytoma 10.0 S100B ENO2
48 encephalomalacia 10.0 S100B GFAP
49 supratentorial cancer 10.0 GFAP ENO2
50 dysembryoplastic neuroepithelial tumor 10.0 S100B GFAP

Graphical network of the top 20 diseases related to Intracranial Cysts:



Diseases related to Intracranial Cysts

Symptoms & Phenotypes for Intracranial Cysts

Drugs & Therapeutics for Intracranial Cysts

Search Clinical Trials , NIH Clinical Center for Intracranial Cysts

Genetic Tests for Intracranial Cysts

Anatomical Context for Intracranial Cysts

MalaCards organs/tissues related to Intracranial Cysts:

40
Brain, Spinal Cord, Temporal Lobe

Publications for Intracranial Cysts

Articles related to Intracranial Cysts:

(show top 50) (show all 162)
# Title Authors PMID Year
1
Basal Ganglia Dysmorphism in Patients With Aicardi Syndrome. 61
33277420 2021
2
Intracranial Cysts. 61
33168211 2020
3
Surgical considerations in Labrune syndrome. 61
32789548 2020
4
Case Report of Cerebellar Endometriosis. 61
32221961 2020
5
A Rare Neurologic Disease that Mimics Cranial Hydatid Cyst: Leukoencephalopathy, Cerebral Calcifications, and Cysts. 61
32195839 2020
6
Meet in the middle: a technique for resecting nasocranial dermoids-technical note and review of the literature. 61
31925508 2020
7
Two different indications of ventriculoperitoneal and cystoperitoneal shunting in six dogs. 61
32384064 2020
8
A Rare Case of Multiple Intracranial Cysts. 61
31250348 2019
9
Incidental Brain MRI Findings in Children: A Systematic Review and Meta-Analysis. 61
31624116 2019
10
Nonneoplastic Cystic Lesions of the Central Nervous System-Histomorphological Spectrum: A Study of 538 Cases. 61
31595123 2019
11
Stereotactic Internal Shunt Placement in Congenital Intracranial Cysts. 61
30576829 2019
12
Intracranial glioependymal (neuroglial) cysts: a systematic review. 61
29802560 2018
13
[Agenesis of the corpus callosum]. 61
29774379 2018
14
Macrocephaly, epilepsy and intracranial cysts: an image to remember. 61
29936447 2018
15
Sonographic Diagnosis of Meningoencephalitis in Newborns and Infants. 61
29534259 2018
16
[Intracranial cystic lesions]. 61
29143062 2018
17
Delleman-Oorthuys syndrome (oculocerebrocutaneous syndrome) in a Nigerian child: a case report. 61
30627696 2018
18
Ophthalmological symptoms in children with intracranial cysts. 61
29051539 2017
19
Diffusion tensor imaging metrics in cystic intracranial mass lesions. 61
29379242 2017
20
Neuroendoscopic surgery in children: does age at intervention influence safety and efficacy? A single-center experience. 61
28753091 2017
21
Intracranial Enterogenous Cysts Close to the Brainstem Treated Through the Nerve Endoscope. 61
28841592 2017
22
Endoscopic management of intracranial cysts: Need of the hour. 61
28488602 2017
23
Do the clinicoradiological outcomes of endoscopic fenestration for intracranial cysts count on age? An institutional experience. 61
28488617 2017
24
Encephalocraniocutaneous lipomatosis (Haberland syndrome): A rare case report. 61
27990391 2016
25
Imaging of Intracranial Cysts. 61
27740988 2016
26
Neuroendoscopy for Intracranial Arachnoid Cysts in Infants: Therapeutic Considerations. 61
26241198 2016
27
Neurocysticercosis, familial cerebral cavernomas and intracranial calcifications: differential diagnosis for adequate management. 61
27332076 2016
28
Imaging alterations due to squamous metaplasia in intracranial neurenteric cysts: A report of two cases. 61
27009777 2016
29
Pulmonary neuroendocrine carcinoma mimicking neurocysticercosis: a case report. 61
27250121 2016
30
Parry-Romberg syndrome with multiple intracranial cysts: A rare case report. 61
27606027 2016
31
Outcome of Fetuses with Supratentorial Extra-Axial Intracranial Cysts: A Systematic Review. 61
27105003 2016
32
Surgical Management of Intracranial Neuroenteric Cysts: The UCSF Experience. 61
26682127 2015
33
[Epidemiology and classification of arachnoid cysts in children]. 61
25843209 2015
34
Intradiploic epidermoid cyst with intracranial hypertension syndrome: Report of two cases and literature review. 61
26433925 2015
35
Delleman Oorthuys syndrome. 61
25624688 2015
36
Multiple cerebral hydatid cysts in 8-year-old boy: A case report and literature review of a rare presentation. 61
26257983 2015
37
Extensive Central Nervous System Cryptococcal Disease Presenting as Immune Reconstitution Syndrome in a Patient with Advanced HIV: Report of a Case and Review of Management Dilemmas and Strategies. 61
25568756 2014
38
Intracranial cystic lesions: a review. 61
25106500 2014
39
Encephalocraniocutaneous lipomatosis: a case report and review of the literature. 61
24881613 2014
40
[Neuroimaging findings in cerebroretinal microangiopathy with calcifications and cysts]. 61
24967922 2014
41
Vertex cephaloceles: a review. 61
23989428 2014
42
[Aicardi syndrome: retrospective study of a series of seven case reports]. 61
24265141 2013
43
Late diagnosis of fetal central nervous system anomalies following a normal second trimester anatomy scan. 61
23712473 2013
44
Surgical management of cortical dysplasia in infancy and early childhood. 61
23694756 2013
45
Intraventricular hemorrhage and multiple intracranial cysts associated with congenital cytomegalovirus infection. 61
23678057 2013
46
Surgical management of intracranial arachnoid cysts: clinical and radiological outcome. 61
23546896 2013
47
Primary multiple cerebral hydatid disease: still symptomatic despite pathologically confirmed death of the cyst. 61
24101271 2013
48
Intracranial cysts: an imagery diagnostic challenge. 61
23737706 2013
49
Impact of protein content on proton diffusibility in intracranial cysts. 61
23059700 2013
50
Clinical and neuroimaging outcomes of surgically treated intracranial cysts in 110 children. 61
23133720 2012

Variations for Intracranial Cysts

Expression for Intracranial Cysts

Search GEO for disease gene expression data for Intracranial Cysts.

Pathways for Intracranial Cysts

Pathways related to Intracranial Cysts according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.33 S100B GFAP ENO2
2
Show member pathways
11.19 S100B GFAP
3 10.85 S100B GFAP

GO Terms for Intracranial Cysts

Sources for Intracranial Cysts

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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