MCID: INT110
MIFTS: 24

Intracranial Cysts

Categories: Neuronal diseases

Aliases & Classifications for Intracranial Cysts

MalaCards integrated aliases for Intracranial Cysts:

Name: Intracranial Cysts 54

Classifications:



Summaries for Intracranial Cysts

NINDS : 54 Arachnoid cysts are cerebrospinal fluid-filled sacs that are located between the brain or spinal cord and the arachnoid membrane, one of the three membranes that cover the brain and spinal cord.   Primary arachnoid cysts are present at birth and are the result of developmental abnormalities in the brain and spinal cord that arise during the early weeks of gestation.  Secondary arachnoid cysts are not as common as primary cysts and develop as a result of head injury, meningitis, or tumors, or as a complication of brain surgery.  The majority of arachnoid cysts form outside the temporal lobe of the brain in an area of the skull known as the middle cranial fossa.  Arachnoid cysts involving the spinal cord are rarer.  The location and size of the cyst determine the symptoms and when those symptoms begin.  Most individuals with arachnoid cysts develop symptoms before the age of 20, and especially during the first year of life, but some people with arachnoid cysts never have symptoms.  Males are four times more likely to have arachnoid cysts than females.  Typical symptoms of an arachnoid cyst around the brain include headache, nausea and vomiting, seizures, hearing and visual disturbances, vertigo, and difficulties with balance and walking.  Arachnoid cysts around the spinal cord compress the spinal cord or nerve roots and cause symptoms such as progressive back and leg pain and tingling or numbness in the legs or arms.  Diagnosis usually involves a brain scan or spine scan using diffusion-weighted MRI (magnetic resonance imaging) which helps distinguish fluid-filled arachnoid cysts from other types of cysts.   

MalaCards based summary : Intracranial Cysts is related to hydrocephalus and bednar tumor. An important gene associated with Intracranial Cysts is ENO2 (Enolase 2), and among its related pathways/superpathways are Neuroscience and Signaling by ERBB4. Affiliated tissues include spinal cord, brain and temporal lobe.

Related Diseases for Intracranial Cysts

Diseases related to Intracranial Cysts via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 133)
# Related Disease Score Top Affiliating Genes
1 hydrocephalus 29.5 ENO2 GFAP
2 bednar tumor 10.1 ENO2 S100B
3 middle cerebral artery infarction 10.1 ENO2 S100B
4 head injury 10.1 ENO2 S100B
5 spondylosis 10.1 ENO2 S100B
6 primitive neuroectodermal tumor of the cervix uteri 10.1 ENO2 GFAP
7 melanotic medulloblastoma 10.1 ENO2 GFAP
8 olfactory neuroblastoma 10.1 ENO2 S100B
9 gemistocytic astrocytoma 10.1 GFAP S100B
10 cerebellar medulloblastoma 10.0 ENO2 GFAP
11 central nervous system primitive neuroectodermal neoplasm 10.0 ENO2 GFAP
12 dysembryoplastic neuroepithelial tumor 10.0 GFAP S100B
13 plexiform schwannoma 10.0 ENO2 GFAP
14 cerebral neuroblastoma 10.0 ENO2 GFAP
15 subependymal glioma 10.0 ENO2 GFAP
16 astroblastoma 10.0 ENO2 GFAP
17 cerebral ventricle cancer 10.0 ENO2 GFAP
18 microcystic meningioma 10.0 ENO2 GFAP
19 pineal gland cancer 10.0 ENO2 GFAP
20 benign ependymoma 10.0 ENO2 GFAP
21 angiocentric glioma 10.0 GFAP S100B
22 subependymoma 10.0 ENO2 GFAP
23 benign glioma 10.0 ENO2 GFAP
24 central neurocytoma 10.0 ENO2 GFAP
25 acute mountain sickness 10.0 ENO2 S100B
26 cystic teratoma 10.0 ENO2 GFAP
27 extraosseous ewing's sarcoma 10.0 ENO2 S100B
28 teratoma 10.0 ENO2 GFAP
29 central nervous system benign neoplasm 10.0 ENO2 GFAP
30 nervous system benign neoplasm 10.0 ENO2 GFAP
31 cerebellar liponeurocytoma 10.0 ENO2 GFAP
32 clear cell sarcoma 10.0 ENO2 S100B
33 medullomyoblastoma 10.0 ENO2 GFAP
34 juvenile pilocytic astrocytoma 10.0 ENO2 GFAP
35 secondary progressive multiple sclerosis 10.0 ENO2 S100B
36 ileum cancer 10.0 ENO2 GFAP
37 adult medulloblastoma 10.0 ENO2 GFAP
38 dysgerminoma of ovary 10.0 ENO2 GFAP
39 ganglioneuroma 10.0 ENO2 GFAP
40 malignant peripheral nerve sheath tumor 10.0 MUC1 S100B
41 myoepithelioma 10.0 GFAP S100B
42 localized hypertrophic neuropathy 10.0 MUC1 S100B
43 sclerosing perineurioma 10.0 MUC1 S100B
44 perineurioma 10.0 MUC1 S100B
45 pilomatrix carcinoma 10.0 ENO2 MUC1
46 reticular perineurioma 10.0 MUC1 S100B
47 scrapie 10.0 ENO2 GFAP
48 sinonasal undifferentiated carcinoma 10.0 ENO2 MUC1
49 non-functioning pituitary adenoma 10.0 MUC1 S100B
50 papillary tumor of the pineal region 10.0 ENO2 MUC1

Graphical network of the top 20 diseases related to Intracranial Cysts:



Diseases related to Intracranial Cysts

Symptoms & Phenotypes for Intracranial Cysts

Drugs & Therapeutics for Intracranial Cysts

Search Clinical Trials , NIH Clinical Center for Intracranial Cysts

Genetic Tests for Intracranial Cysts

Anatomical Context for Intracranial Cysts

MalaCards organs/tissues related to Intracranial Cysts:

41
Spinal Cord, Brain, Temporal Lobe, Kidney, Ovary, Pituitary, Pineal

Publications for Intracranial Cysts

Articles related to Intracranial Cysts:

(show all 43)
# Title Authors Year
1
Macrocephaly, epilepsy and intracranial cysts: an image to remember. ( 29936447 )
2018
2
Do the clinicoradiological outcomes of endoscopic fenestration for intracranial cysts count on age? An institutional experience. ( 28488617 )
2017
3
Ophthalmological symptoms in children with intracranial cysts. ( 29051539 )
2017
4
Endoscopic management of intracranial cysts: Need of the hour. ( 28488602 )
2017
5
Parry-Romberg syndrome with multiple intracranial cysts: A rare case report. ( 27606027 )
2016
6
Outcome of Fetuses with Supratentorial Extra-Axial Intracranial Cysts: A Systematic Review. ( 27105003 )
2016
7
Imaging of Intracranial Cysts. ( 27740988 )
2016
8
Impact of protein content on proton diffusibility in intracranial cysts. ( 23059700 )
2013
9
Intracranial cysts: an imagery diagnostic challenge. ( 23737706 )
2013
10
Intraventricular hemorrhage and multiple intracranial cysts associated with congenital cytomegalovirus infection. ( 23678057 )
2013
11
Clinical and neuroimaging outcomes of surgically treated intracranial cysts in 110 children. ( 23133720 )
2012
12
Intracranial cysts: large-scale information is needed. ( 22308833 )
2011
13
Intracranial cysts containing cerebrospinal fluid-like fluid: results of endoscopic neurosurgery in a series of 64 consecutive cases. ( 21311305 )
2011
14
The endocrine spectrum of intracranial cysts in childhood and review of the literature. ( 22308834 )
2011
15
Fetal intracranial cysts: prenatal diagnosis and outcome. ( 22439038 )
2009
16
Stent placement for intracranial cysts by combined stereotactic/endoscopic surgery. ( 17041520 )
2006
17
Intracranial cysts: radiologic-pathologic correlation and imaging approach. ( 16714456 )
2006
18
Endoscopic management of intracranial cysts. ( 16398484 )
2005
19
Neuroendoscopic transventricular ventriculocystostomy in treatment for intracranial cysts. ( 16122006 )
2005
20
Neuroendoscopic basket dilation technique for the fenestration of the ventricular wall or intracranial cysts--technical note. ( 15253551 )
2004
21
Neuroendoscopic surgery of intracranial cysts in adults. ( 15197568 )
2004
22
Malformative intracranial cysts: diagnosis and outcome. ( 12879342 )
2003
23
Virtual endoscopy combined with intraoperative neuronavigation for planning of endoscopic surgery in patients with occlusive hydrocephalus and intracranial cysts. ( 11914801 )
2002
24
Endoscopy of intracranial cysts in the adult patient. ( 12353169 )
2002
25
Value of constructive interference in steady-state three-dimensional, Fourier transformation magnetic resonance imaging for the neuroendoscopic treatment of hydrocephalus and intracranial cysts. ( 11383732 )
2001
26
The contribution of prenatal diagnosis to the understanding of malformative intracranial cysts: state of the art. ( 11151710 )
2000
27
CSF flow studies of intracranial cysts and cyst-like lesions achieved using reversed fast imaging with steady-state precession MR sequences. ( 10730641 )
2000
28
Evaluation of intracranial cysts by intraoperative MR. ( 9702881 )
1998
29
Endoscopic neurosurgery and endoscope-assisted microneurosurgery for the treatment of intracranial cysts. ( 9848846 )
1998
30
The combined use of image-guided frameless stereotaxy and neuroendoscopy for the surgical management of occlusive hydrocephalus and intracranial cysts. ( 10070462 )
1998
31
Nonneoplastic intracranial cysts and cystic lesions. ( 7654409 )
1995
32
Intracranial cysts in autosomal dominant polycystic kidney disease. ( 7490613 )
1995
33
A special cyst puncture catheter for use in thick-walled or mobile intracranial cysts. ( 8121560 )
1994
34
[Benign intracranial cysts and certain congenital neoplasms]. ( 8162151 )
1994
35
Congenital intracranial cysts: clinical findings, diagnosis, treatment and follow-up. A multicenter, retrospective long-term evaluation of 72 children. ( 8110712 )
1993
36
The role of posttraumatic intracranial cysts in the pathogeny of late epileptic seizures as exemplified by two patients. ( 8534143 )
1993
37
Immunohistochemical study of intracranial cysts. ( 7508303 )
1993
38
Histological and ultrastructural findings of benign intracranial cysts. ( 8220794 )
1993
39
Psychiatric presentations of intracranial cysts. ( 2577719 )
1989
40
Immunohistochemical study of intracranial cysts. ( 3200389 )
1988
41
Intracranial cysts. ( 424536 )
1979
42
The diagnosis of intracranial cysts by means of the brain scan. ( 4295909 )
1968
43
Classification of intracranial cysts. ( 13969342 )
1962

Variations for Intracranial Cysts

Expression for Intracranial Cysts

Search GEO for disease gene expression data for Intracranial Cysts.

Pathways for Intracranial Cysts

Pathways related to Intracranial Cysts according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.33 ENO2 GFAP S100B
2
Show member pathways
11.19 GFAP S100B
3 10.85 GFAP S100B

GO Terms for Intracranial Cysts

Cellular components related to Intracranial Cysts according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 myelin sheath GO:0043209 8.62 ENO2 GFAP

Biological processes related to Intracranial Cysts according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 long-term synaptic potentiation GO:0060291 8.62 GFAP S100B

Sources for Intracranial Cysts

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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