MCID: INT010
MIFTS: 45

Intracranial Embolism

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Intracranial Embolism

MalaCards integrated aliases for Intracranial Embolism:

Name: Intracranial Embolism 12 44 15 73
Cerebral Embolism 12 55 73
Cerebral Embolism with Cerebral Infarction 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4372
ICD10 33 I66
ICD9CM 35 434.1
MeSH 44 D020766
SNOMED-CT 68 75543006

Summaries for Intracranial Embolism

MalaCards based summary : Intracranial Embolism, also known as cerebral embolism, is related to endocarditis and thrombosis. An important gene associated with Intracranial Embolism is PLG (Plasminogen), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Selenium Micronutrient Network. The drugs Aspirin and Clopidogrel have been mentioned in the context of this disorder. Affiliated tissues include brain, heart and bone, and related phenotypes are homeostasis/metabolism and reproductive system

Related Diseases for Intracranial Embolism

Diseases related to Intracranial Embolism via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 184)
# Related Disease Score Top Affiliating Genes
1 endocarditis 30.4 F2 PLAT SERPINC1
2 thrombosis 30.0 F2 PLAT SERPINC1
3 patent foramen ovale 30.0 F12 F2 PLAT SERPINC1
4 thrombophilia due to thrombin defect 29.8 F2 PLAT SERPINC1
5 intracranial thrombosis 29.7 PLG SERPINC1
6 coronary thrombosis 29.6 PLAT SERPINC1
7 arteries, anomalies of 29.5 PLAT PLG SERPINC1
8 cerebrovascular disease 29.5 F12 F2 PLAT
9 antiphospholipid syndrome 29.4 F2 PLAT SERPINC1
10 thrombocytosis 29.3 F2 SERPINC1
11 myocardial infarction 29.3 F2 PLAT PLG SERPINC1 SERPINF2
12 acute myocardial infarction 29.3 PLAT PLG SERPINC1 SERPINF2
13 marantic endocarditis 29.3 F2 PLAT SERPINC1 SERPINF2
14 pulmonary embolism 28.9 F2 PLAT SERPINC1 SERPINF2
15 atrial fibrillation 10.3
16 ligneous conjunctivitis 10.2 PLAT PLG
17 inferior myocardial infarction 10.2 PLAT PLG
18 central retinal artery occlusion 10.2 PLAT PLG
19 fibrinolytic defect 10.2 PLAT SERPINC1
20 argentine hemorrhagic fever 10.2 PLAT SERPINC1
21 occlusion precerebral artery 10.2 PLAT PLG
22 basilar artery occlusion 10.2 PLAT PLG
23 posterior myocardial infarction 10.2 PLAT SERPINC1
24 encephalopathy, familial, with neuroserpin inclusion bodies 10.2 PLAT SERPINC1
25 pleuropneumonia 10.2 PLAT SERPINC1
26 carotid artery dissection 10.1 PLAT PLG
27 angina pectoris 10.1 PLAT SERPINC1
28 hemorrhagic fever 10.1 F2 SERPINC1
29 cerebral falx meningioma 10.1 F2 PLG
30 purpura 10.1 F2 SERPINC1
31 cholesterol embolism 10.1 GIPC1 TAX1BP3
32 femoral neuropathy 10.1 F2 PLG
33 factor xii deficiency 10.1 F12 SERPINC1
34 spinal cord infarction 10.1 F2 SERPINC1
35 fournier gangrene 10.1 F2 SERPINC1
36 prothrombin deficiency, congenital 10.1 F2 SERPINC1
37 anterior cranial fossa meningioma 10.1 F2 PLG
38 retinal artery occlusion 10.1 F2 SERPINC1
39 sagittal sinus thrombosis 10.1 F2 SERPINC1
40 amegakaryocytic thrombocytopenia, congenital 10.1 GIPC1 TAX1BP3
41 ischemic colitis 10.1 F2 SERPINC1
42 subendocardial myocardial infarction 10.1 F2 SERPINC1
43 sneddon syndrome 10.1 F2 SERPINC1
44 esophageal varix 10.1 F2 SERPINC1
45 hepatic infarction 10.1 F2 SERPINC1
46 antithrombin iii deficiency 10.1 F2 SERPINC1
47 post-thrombotic syndrome 10.1 F2 SERPINC1
48 hypersplenism 10.1 F2 SERPINC1
49 endocardium disease 10.1 F2 PLG
50 peripheral vertigo 10.1 F2 SERPINC1

Comorbidity relations with Intracranial Embolism via Phenotypic Disease Network (PDN): (show all 27)


Acute Cystitis Aortic Valve Disease 1
Benign Essential Hypertension Cerebral Atherosclerosis
Cerebrovascular Disease Chronic Myocardial Ischemia
Cortical Blindness Decubitus Ulcer
Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation Familial Atrial Fibrillation
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Hypothyroidism
Intermediate Coronary Syndrome Intracranial Thrombosis
Ischemic Heart Disease Mitral Valve Disease
Mitral Valve Stenosis Peripheral Vascular Disease
Respiratory Failure Rheumatic Heart Disease
Sinoatrial Node Disease Spastic Hemiplegia
Swallowing Disorders Transient Cerebral Ischemia
Tricuspid Valve Disease

Graphical network of the top 20 diseases related to Intracranial Embolism:



Diseases related to Intracranial Embolism

Symptoms & Phenotypes for Intracranial Embolism

MGI Mouse Phenotypes related to Intracranial Embolism:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.5 F12 F2 GIPC1 PLAT PLG SERPINC1
2 reproductive system MP:0005389 9.02 F12 F2 PLAT PLG SERPINC1

Drugs & Therapeutics for Intracranial Embolism

Drugs for Intracranial Embolism (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 55)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Aspirin Approved, Vet_approved Phase 4,Phase 3,Not Applicable 50-78-2 2244
2
Clopidogrel Approved Phase 4,Phase 3 113665-84-2, 120202-66-6 60606
3
Acenocoumarol Approved, Investigational Phase 4 152-72-7 9052 54676537
4
Ticlopidine Approved Phase 4 55142-85-3 5472
5 Antipyretics Phase 4,Phase 3
6 Purinergic P2Y Receptor Antagonists Phase 4,Phase 3
7 Analgesics Phase 4,Phase 3
8 Neurotransmitter Agents Phase 4,Phase 3
9 Anti-Inflammatory Agents, Non-Steroidal Phase 4,Phase 3
10 Fibrinolytic Agents Phase 4,Phase 3,Phase 2,Not Applicable
11 Analgesics, Non-Narcotic Phase 4,Phase 3
12 Purinergic P2 Receptor Antagonists Phase 4,Phase 3
13 Antirheumatic Agents Phase 4,Phase 3
14 Peripheral Nervous System Agents Phase 4,Phase 3
15 Cyclooxygenase Inhibitors Phase 4,Phase 3
16 Anti-Inflammatory Agents Phase 4,Phase 3
17 Platelet Aggregation Inhibitors Phase 4,Phase 3
18 Anticoagulants Phase 4,Phase 3,Phase 2
19 Cytochrome P-450 CYP2C19 Inhibitors Phase 4
20 Cytochrome P-450 Enzyme Inhibitors Phase 4
21
Warfarin Approved Phase 3 81-81-2 6691 54678486
22
Heparin Approved, Investigational Phase 2, Phase 3 9005-49-6 772 46507594
23
Dalteparin Approved Phase 2, Phase 3 9005-49-6
24
Serine Approved, Nutraceutical Phase 3 56-45-1 5951
25 Tissue Plasminogen Activator Phase 3,Phase 2,Not Applicable
26
protease inhibitors Phase 3
27 Antithrombin III Phase 3
28 HIV Protease Inhibitors Phase 3
29 Antithrombins Phase 3
30 Dabigatran Phase 3
31 Serine Proteinase Inhibitors Phase 3
32 Plasminogen Phase 2, Phase 3,Not Applicable
33 Calcium, Dietary Phase 2, Phase 3
34 calcium heparin Phase 2, Phase 3
35 Heparin, Low-Molecular-Weight Phase 2, Phase 3
36 Anesthetics Phase 2
37
Estradiol Approved, Investigational, Vet_approved 50-28-2 5757
38
Levonorgestrel Approved, Investigational 17489-40-6, 797-63-7 13109
39
Ethinyl Estradiol Approved 57-63-6 5991
40 Estradiol valerate Approved, Investigational, Vet_approved 979-32-8
41
Polyestradiol phosphate Approved 28014-46-2
42 Pharmaceutical Solutions Not Applicable
43 Estradiol 17 beta-cypionate
44 Hormones, Hormone Substitutes, and Hormone Antagonists
45 Ethinyl estradiol, levonorgestrel drug combination
46 Estradiol 3-benzoate
47 Contraceptive Agents
48 Norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination
49 Norinyl
50 Contraceptives, Oral

Interventional clinical trials:

(show all 36)
# Name Status NCT ID Phase Drugs
1 Incidence of Acute Cerebrovascular Events Using Either Minimized or Standard Cardiopulmonary Bypass Circuit Unknown status NCT00862160 Phase 4
2 Cerebral Embolic Load in Patients Undergoing Surgical Aortic Valve Replacement: A Comparison of the Conventional With the Minimized Extracorporeal Circulation Technique Using Transcranial Doppler Ultrasound Completed NCT02308566 Phase 4
3 Dual Antiplatelet Therapy Versus Oral Anticoagulation for a Short Time to Prevent Cerebral Embolism After TAVI Recruiting NCT01642134 Phase 4 aspirin+clopidogrel (Duoplavin)
4 Ultrasound Enhanced Thrombolytic Therapy of Middle Cerebral Artery Occlusion Unknown status NCT00336596 Phase 3
5 Dual AntiPlatelet Therapies for Prevention of Periinterventional Embolic Events in TAVI Unknown status NCT03001960 Phase 3 Preloading before TAVI;Postloading after TAVI
6 Stroke Prevention in Sickle Cell Anemia (STOP 1) Completed NCT00000592 Phase 3
7 Boston Area Anticoagulation Trial for Atrial Fibrillation (BAATAF) Completed NCT00000517 Phase 3 warfarin
8 A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis (RE-SPECT CVT) Completed NCT02913326 Phase 3 Dabigatran etexilate;Warfarin
9 Evaluation of the TriActiv ProGuard System During Carotid Artery Stenting Terminated NCT00395785 Phase 2, Phase 3
10 Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis Terminated NCT01204333 Phase 2, Phase 3 Endovascular thrombolysis;Heparin
11 Autologous Bone Marrow Mononuclear Cell Transplantation for Stroke Patients Completed NCT01028794 Phase 1, Phase 2
12 Prevention for the Restenosis of Intracranial Artery Stent Implantation Treated With Herbal Medicine C117 Not yet recruiting NCT03008798 Phase 2 Herbal Medicine C-117;The Placebo of Herbal Medicine C-117
13 Effect of ARC1779 on Cerebral Microembolism in Patients Undergoing Carotid Endarterectomy Terminated NCT00742612 Phase 2 ARC1779 Injection;Placebo (normal saline)
14 Evaluation of Cerebral Thrombembolism After TAVR Unknown status NCT02758964
15 TCD Detection of Gas and Solid Micro-Emboli in Patients Undergoing Coronary Artery Bypass Grafting (CABG): The Influence of Proximal Anastomosis Technique Unknown status NCT00294814 Not Applicable
16 A Registry Study of Shuxuening Injection Used in Hospitals in China Unknown status NCT01752946
17 Surgical Tourniquets and Cerebral Emboli Completed NCT02240732
18 Left Atrial Appendage Closure During Open Heart Surgery Completed NCT02378116 Not Applicable
19 Cerebral Microembolism During Hemodialysis Completed NCT02021045
20 Cerebral Embolism (CE) in Catheter Ablation of Atrial Fibrillation (AF) Completed NCT01361295 Not Applicable
21 Incidence and Severity of Silent and Apparent Cerebral Embolism After Conventional and Minimal-invasive Transfemoral Aortic Valve Replacement Completed NCT00883285
22 Transcranial Doppler (TCD) Ultrasound of Subjects Enrolled in BABY HUG - Ancillary to BABY HUG Completed NCT00059293
23 Comparison of the Radiological Pattern Between the Cerebral Stroke of Arterial and Venous Origin Completed NCT03611894
24 Randomized Clinical Trial of Polyester vs. Polyurethane Patch for Carotid Endarterectomy Completed NCT02341196 Not Applicable
25 Modern Ultrasound Techniques in the Evaluation of Cerebral Venous Sinuses in Neonates Completed NCT00555932 Not Applicable
26 Study Of Lybrel In Relation To Venous Thromboembolism Completed NCT01297348 90ug levonorgestrel / 20 ug ethinyl estradiol;Oral Contraceptives containing 20 ug of ethinyl estradiol
27 Impact of Cranioplasty On Cerebral Perfusion Completed NCT01113645
28 Electrical Cardioversion of Recent Onset Atrial Fibrillation - Silent Thromboembolic Events, Reverse Atrial Remodeling Recruiting NCT02955004
29 Rheoparin-coated Tubing System for Minimized Extracorporeal Circulation (MECC) Recruiting NCT02321917 Not Applicable
30 Cerebral Microembolism in Cardiology Recruiting NCT03802760
31 Magnetically Enhanced Diffusion for Acute Ischaemic Stroke (MEDIS) Trial Recruiting NCT03098732 Not Applicable
32 Cerebral Microembolism in the Critically Ill With Acute Kidney Injury Recruiting NCT02621749 Not Applicable
33 Thrombolysis and RIPC in Acute Ischemic Stroke Recruiting NCT03218293 Not Applicable
34 Stroke and Cerebrovascular Diseases Registry Recruiting NCT03281590
35 Cerebral Venous Sinus Thrombosis: Re-exploration of Clinical Assessment Scales Recruiting NCT03273179
36 Intracranial Thrombosis Aspiration Catheter for Recanalization in Acute Ischemic Stroke Therapy (RECOVER) Not yet recruiting NCT03753061 Not Applicable

Search NIH Clinical Center for Intracranial Embolism

Cochrane evidence based reviews: intracranial embolism

Genetic Tests for Intracranial Embolism

Anatomical Context for Intracranial Embolism

MalaCards organs/tissues related to Intracranial Embolism:

41
Brain, Heart, Bone, Bone Marrow, Kidney, Liver, Spinal Cord

Publications for Intracranial Embolism

Articles related to Intracranial Embolism:

(show top 50) (show all 349)
# Title Authors Year
1
Paradoxical Cerebral Embolism after Gastrointestinal Endoscopy in a Patient with Crohn's Disease. ( 29501267 )
2018
2
Atrial fibrillation type matters: greater infarct volume and worse neurological defects seen in acute cardiogenic cerebral embolism due to persistent or permanent rather than paroxysmal atrial fibrillation. ( 29244081 )
2018
3
Cerebral Embolism Following Transcarotid Transcatheter Aortic Valve Replacement. ( 29301616 )
2018
4
Right-left propensity of cardiogenic cerebral embolism in standard versus bovine aortic arch variant. ( 29327485 )
2018
5
Calcified Cerebral Embolism Due to a Calcified Amorphous Tumor. ( 29478938 )
2018
6
Silent cerebral embolism in cryoballoon ablation of atrial fibrillation: When details matter. ( 30048692 )
2018
7
Thrombus Reformation in the Pulmonary Vein Stump Confirmed 16 Months After Cerebral Embolism on the Day After Left Upper Lobectomy for Lung Cancer. ( 30077602 )
2018
8
Cerebral embolism secondary to cardiac amyloidosis: A case report and literature review. ( 29250142 )
2017
9
Mechanical thrombectomy during ischaemic stroke due to a calcified cerebral embolism. ( 26304657 )
2017
10
Protection Against Cerebral Embolism During Transcatheter Aortic Valve Replacement. ( 27815101 )
2017
11
Frequency and clinical course of cerebral embolism in patients undergoing transcatheter left atrial appendage closure. ( 28218603 )
2017
12
Bilateral cerebral embolism as a characteristic feature of patients with Trousseau syndrome. ( 28431956 )
2017
13
Calcified cerebral embolism: what the clinician needs to know. ( 28505318 )
2017
14
Effect of air removal with extracorporeal balloon inflation on incidence of asymptomatic cerebral embolism during cryoballoon ablation of atrial fibrillation. ( 28559090 )
2017
15
Brachial-Ankle Pulse Wave Velocity as a Predictor of Silent Cerebral Embolism after Carotid Artery Stenting. ( 28602632 )
2017
16
Computed Tomography Score of Aortic Valve Tissue May Predict Cerebral Embolism During Transcatheter Aortic Valve Implantation. ( 28797420 )
2017
17
Integrin α4 Overexpression on Rat Mesenchymal Stem Cells Enhances Transmigration and Reduces Cerebral Embolism After Intracarotid Injection. ( 28916665 )
2017
18
Combined ostium secundum type ASD and pulmonary arterial thromboembolism causing pulmonary artery enlargement, pulmonary hypertension and recurrent paradoxical cerebral embolism due to deep venous thrombosis. ( 26814633 )
2016
19
Assessment of cerebral embolism and vascular reserve parameters in patients with carotid artery stenosis. ( 27591061 )
2016
20
Successful treatment of neutropenic MRSA bacteremia with septic superior vena cava thrombus and cerebral embolism using high-dose daptomycin. ( 26490881 )
2016
21
Associations between Cerebral Embolism and Carotid Intraplaque Hemorrhage during Protected Carotid Artery Stenting. ( 26542236 )
2016
22
Low rate of asymptomatic cerebral embolism and improved procedural efficiency with the novel pulmonary vein ablation catheter GOLD: results of the PRECISION GOLD trial. ( 26826134 )
2016
23
Silent Cerebral Embolism After Catheter Ablation for Atrial Fibrillation - Unresolved Issue or Too Much Concern? ( 26948985 )
2016
24
Efficacy of Solitaire Stent Arterial Embolectomy in Treating Acute Cardiogenic Cerebral Embolism in 17 Patients. ( 27090916 )
2016
25
Bihemispheric Paradoxical Cerebral Embolism in a Patient with Pulmonary Thromboembolism and Presumptive Fistula Right-to-Left Shunt. ( 27105566 )
2016
26
Cerebral Embolism During Transcatheter Aortic Valve Replacement: The BRAVO-3 MRI Study. ( 27208464 )
2016
27
Cerebral Embolism: A Silent Iatrogenic Complication of TAVR That Needs Voiced Consideration. ( 27491902 )
2016
28
Cerebral embolism complicating left atrial myxoma: a case report. ( 27642478 )
2016
29
Mobile thrombus originating from densely calcified mitral annulus with cerebral embolism. ( 27751264 )
2016
30
Spontaneous dissecting aneurysm of the left atrium complicated by cerebral embolism: A report of two cases with review of literature. ( 27751267 )
2016
31
Corrigendum to "Septic pulmonary and cerebral embolism caused by community-associated methicillin-resistant Staphylococcus aureus in a healthy child" [J Microbiol Immunol Infect 49(5) (2016) 826-827]. ( 27939029 )
2016
32
Septic pulmonary and cerebral embolism caused by community-associated methicillin-resistant Staphylococcus aureus in a healthy child. ( 25649487 )
2016
33
Cerebral embolism through hematogenous dissemination of pulmonary mucormycosis complicating relapsed leukemia. ( 26722589 )
2015
34
Percutaneous patent foramen ovale closure: the Paradoxical Cerebral Embolism Prevention Registry. ( 25727752 )
2015
35
Consequence of cerebral embolism after transcatheter aortic valve implantation compared with contemporary surgical aortic valve replacement: effect on health-related quality of life. ( 25737407 )
2015
36
Early relapsing calcified cerebral embolism. ( 25817624 )
2015
37
A case of severe cerebral embolism after chemotherapy for HER2-positive gastric cancer. ( 25885256 )
2015
38
Prevention of cerebral embolism progression by emergency surgery of the left atrial myxoma. ( 25954312 )
2015
39
The cerebral embolism evoked by intra-arterial delivery of allogeneic bone marrow mesenchymal stem cells in rats is related to cell dose and infusion velocity. ( 25971703 )
2015
40
Thrombus Removal by Acute-phase Endovascular Reperfusion Therapy to Treat Cerebral Embolism Caused by Thrombus in the Pulmonary Vein Stump after Left Upper Pulmonary Lobectomy: Case Report. ( 28663958 )
2015
41
Letter by Myers and Kalangos regarding article, "fluttering thrombus in patent foramen ovale with paradoxical and cerebral embolism". ( 25462829 )
2014
42
Response to letter regarding article "fluttering thrombus in patent foramen ovale with paradoxycal and cerebral embolism". ( 25462830 )
2014
43
Fluttering thrombus in patent foramen ovale with paradoxical and cerebral embolism. ( 24566069 )
2014
44
Peripartum cardiomyopathy with biventricular thrombus which led to massive cerebral embolism. ( 30534300 )
2014
45
Cerebral embolism in the perioperative period in patients post interventional treatment of carotid artery stenosis: a preliminary report. ( 24846363 )
2014
46
Successful management of cerebral embolism during TAVR. ( 24398707 )
2014
47
Löffler endocarditis with multiple cerebral embolism. ( 24529355 )
2014
48
Rosuvastatin improves plaque morphology in cerebral embolism patients with normal low-density lipoprotein and severe aortic arch plaque. ( 24739590 )
2014
49
Surgery for infective endocarditis complicated by cerebral embolism: a consecutive series of 375 patients. ( 24837722 )
2014
50
Left atrial appendage dysfunction in acute cerebral embolism patients with sinus rhythm: correlation with pulse wave tissue Doppler imaging. ( 24852338 )
2014

Variations for Intracranial Embolism

Expression for Intracranial Embolism

Search GEO for disease gene expression data for Intracranial Embolism.

Pathways for Intracranial Embolism

Pathways related to Intracranial Embolism according to GeneCards Suite gene sharing:

(show all 12)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.88 F12 F2 PLAT PLG SERPINC1 SERPINF2
2
Show member pathways
11.99 F2 PLAT PLG
3
Show member pathways
11.68 F2 PLAT PLG
4
Show member pathways
11.63 F12 F2 PLAT PLG SERPINC1 SERPINF2
5 11.3 PLAT PLG
6 11.24 F12 F2 PLAT PLG SERPINC1 SERPINF2
7 11.23 F12 PLAT PLG
8 11.18 PLAT PLG
9 10.92 F2 GIPC1 PLG
10 10.82 PLAT PLG
11 10.76 F2 PLG
12 10.45 PLAT PLG SERPINF2

GO Terms for Intracranial Embolism

Cellular components related to Intracranial Embolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular region GO:0005576 9.8 F12 F2 PLAT PLG SERPINC1 SERPINF2
2 extracellular space GO:0005615 9.73 F12 F2 PLAT PLG SERPINC1 SERPINF2
3 collagen-containing extracellular matrix GO:0062023 9.46 PLAT PLG SERPINC1 SERPINF2
4 platelet alpha granule lumen GO:0031093 9.37 PLG SERPINF2
5 blood microparticle GO:0072562 9.26 F2 PLG SERPINC1 SERPINF2
6 extracellular exosome GO:0070062 9.23 F12 F2 GIPC1 PLAT PLG SERPINC1

Biological processes related to Intracranial Embolism according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.81 F12 F2 PLAT PLG
2 cellular protein metabolic process GO:0044267 9.67 F2 PLG SERPINC1
3 acute-phase response GO:0006953 9.52 F2 SERPINF2
4 regulation of blood coagulation GO:0030193 9.5 F12 F2 SERPINC1
5 negative regulation of proteolysis GO:0045861 9.48 F2 PLAT
6 positive regulation of collagen biosynthetic process GO:0032967 9.46 F2 SERPINF2
7 hemostasis GO:0007599 9.46 F12 F2 PLG SERPINC1
8 blood coagulation, intrinsic pathway GO:0007597 9.43 F12 F2
9 negative regulation of fibrinolysis GO:0051918 9.43 F2 PLG SERPINF2
10 positive regulation of blood coagulation GO:0030194 9.4 F12 F2
11 positive regulation of fibrinolysis GO:0051919 9.37 F12 PLG
12 blood coagulation GO:0007596 9.35 F12 F2 PLAT PLG SERPINC1
13 fibrinolysis GO:0042730 9.02 F12 F2 PLAT PLG SERPINF2

Molecular functions related to Intracranial Embolism according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.56 F12 F2 PLAT PLG
2 signaling receptor binding GO:0005102 9.46 F2 GIPC1 PLAT PLG
3 serine-type endopeptidase activity GO:0004252 9.26 F12 F2 PLAT PLG
4 serine-type peptidase activity GO:0008236 8.92 F12 F2 PLAT PLG

Sources for Intracranial Embolism

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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