Intracranial Primitive Neuroectodermal Tumor disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Intracranial Primitive Neuroectodermal Tumor

MalaCards integrated aliases for Intracranial Primitive Neuroectodermal Tumor:

Name: Intracranial Primitive Neuroectodermal Tumor ¹¹ ¹⁴

Intracranial Primitive Neuroectodermal Neoplasm ⁷¹

Intracranial Pnet ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases Skin diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:4788

NCIt ⁴⁹ C5817

UMLS ⁷¹ C1334246

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Summaries for Intracranial Primitive Neuroectodermal Tumor

MalaCards based summary: Intracranial Primitive Neuroectodermal Tumor, also known as intracranial primitive neuroectodermal neoplasm, is related to differentiating neuroblastoma and islet cell tumor. An important gene associated with Intracranial Primitive Neuroectodermal Tumor is CD99 (CD99 Molecule (Xg Blood Group)). Affiliated tissues include pineal and brain.

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Related Diseases for Intracranial Primitive Neuroectodermal Tumor

Diseases related to Intracranial Primitive Neuroectodermal Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 177)

#	Related Disease	Score	Top Affiliating Genes
1	differentiating neuroblastoma	29.9	SYP ENO2
2	islet cell tumor	29.7	SYP ENO2
3	supratentorial primitive neuroectodermal tumor	29.7	SYP ENO2 CD99
4	neuroblastoma	29.3	SYP RASSF1 EWSR1 ENO2
5	ewing sarcoma	28.9	SYP RASSF1 FLI1 EWSR1 ENO2 CD99
6	retinoblastoma	11.4
7	monophasic synovial sarcoma	10.2	EWSR1 CD99
8	biphasic synovial sarcoma	10.2	EWSR1 CD99
9	kidney fibrosarcoma	10.2	EWSR1 CD99
10	epithelioid cell synovial sarcoma	10.2	EWSR1 CD99
11	conventional osteosarcoma	10.1	EWSR1 CD99
12	central nervous system neuroblastoma	10.1
13	intracranial hypertension	10.1
14	kidney clear cell sarcoma	10.1	EWSR1 CD99
15	synovium cancer	10.1	EWSR1 CD99
16	parachordoma	10.1	EWSR1 ENO2
17	epithelioid sarcoma	10.1	FLI1 EWSR1
18	epithelioid malignant peripheral nerve sheath tumor	10.0	EWSR1 ENO2
19	myxoid chondrosarcoma	10.0	EWSR1 ENO2
20	myocardium cancer	10.0	SYP CD99
21	connective tissue benign neoplasm	9.9	EWSR1 ENO2
22	chordoid meningioma	9.9	SYP EWSR1
23	langerhans cell histiocytosis	9.9
24	histiocytosis	9.9
25	thymus sarcomatoid carcinoma	9.9	SYP EWSR1
26	lymphoblastic lymphoma	9.9	FLI1 ENO2 CD99
27	alveolar soft part sarcoma	9.9	EWSR1 ENO2
28	extraskeletal mesenchymal chondrosarcoma	9.9	EWSR1 ENO2 CD99
29	mesenchymal chondrosarcoma	9.9	EWSR1 ENO2 CD99
30	embryonal rhabdomyosarcoma	9.9	EWSR1 ENO2 CD99
31	blastoma	9.9	SYP ENO2
32	skin benign neoplasm	9.9	EWSR1 ENO2
33	malignant melanocytic neoplasm of the peripheral nerve sheath	9.9	SYP ENO2
34	anal neuroendocrine tumor	9.9	SYP ENO2
35	cerebral neuroblastoma	9.9	SYP ENO2
36	neuronal intestinal dysplasia, type b	9.9	SYP ENO2
37	thymus small cell carcinoma	9.9	SYP ENO2
38	small cell carcinoma	9.9	SYP ENO2
39	gastric small cell carcinoma	9.9	SYP ENO2
40	optic nerve astrocytoma	9.9	SYP ENO2
41	breast neuroendocrine neoplasm	9.9	SYP ENO2
42	cloacogenic carcinoma	9.9	SYP ENO2
43	pineal region teratoma	9.9	SYP ENO2
44	middle ear adenoma	9.9	SYP ENO2
45	colon neuroendocrine neoplasm	9.9	SYP ENO2
46	bile duct mucinous adenocarcinoma	9.9	SYP ENO2
47	ampulla of vater benign neoplasm	9.9	SYP ENO2
48	partial cryptophthalmia	9.9	SYP ENO2
49	auditory system benign neoplasm	9.9	SYP ENO2
50	carotid body cancer	9.9	SYP ENO2

Graphical network of the top 20 diseases related to Intracranial Primitive Neuroectodermal Tumor:

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Symptoms & Phenotypes for Intracranial Primitive Neuroectodermal Tumor

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Drugs & Therapeutics for Intracranial Primitive Neuroectodermal Tumor

Search Clinical Trials, NIH Clinical Center for Intracranial Primitive Neuroectodermal Tumor

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Genetic Tests for Intracranial Primitive Neuroectodermal Tumor

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Anatomical Context for Intracranial Primitive Neuroectodermal Tumor

Organs/tissues related to Intracranial Primitive Neuroectodermal Tumor:

MalaCards : Pineal, Brain

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Publications for Intracranial Primitive Neuroectodermal Tumor

Articles related to Intracranial Primitive Neuroectodermal Tumor:

(show all 13)

#	Title	Authors	PMID	Year
1	A rare case of pediatric primary central nervous system differentiating neuroblastoma: an unusual and rare intracranial primitive neuroectodermal tumor (a case report). ⁶²	Borni M...Boudawara MZ	34795814	2021
2	Effects of Proton Center Closure on Pediatric Case Volume and Resident Education at an Academic Cancer Center. ⁶²	Galle JO...Ellsworth SG	29413283	2018
3	Refractory LCH With Secondary Intracranial PNET: A Case Report and Review of Literature. ⁶²	Chayapathi V...Kalra M	28859038	2018
4	Trilateral retinoblastoma: neuroimaging characteristics and value of routine brain screening on admission. ⁶²	Rodjan F...Castelijns JA	22802019	2012
5	Guidelines for imaging retinoblastoma: imaging principles and MRI standardization. ⁶²	de Graaf P...European Retinoblastoma Imaging Collaboration (ERIC)	21850471	2012
6	MRI features of intracranial primitive neuroectodermal tumors in adults: comparing with histopathological findings. ⁶²	Shi H...Liu D	15165129	2004
7	Evaluation of dietetic intervention in children with medulloblastoma or supratentorial primitive neuroectodermal tumors. ⁶²	Bakish J...Bouffet E	12942570	2003
8	Trilateral retinoblastoma: is the location of the intracranial tumor important? ⁶²	Paulino AC	10391573	1999
9	[Intracranial primitive neuroectodermal tumor in an infant: a case report]. ⁶²	Yoshizato K...Nishio S	10190159	1999
10	Peripheral-type primitive neuroectodermal tumor arising in the tentorium. Case report. ⁶²	Katayama Y...Koshinaga M	10413168	1999
11	Primitive Neuroectodermal Tumor of the Meninges: An Histological, Immunohistochemical, Ultrastructural, and Cytogenetic Study. ⁶²	Papotti M...Bussolati G	12114719	1998
12	Leptomeningeal fibrosis and the delayed diagnosis of a central nervous system neoplasm (primitive neuroectodermal tumor). ⁶²	Robertson PL...Brunberg JA	9044409	1997
13	Association of a suprasellar mass and intraocular retinoblastoma: a variant of pineal trilateral retinoblastoma? ⁶²	Bejjani GK...Packer R	9309793	1996

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Genes for Intracranial Primitive Neuroectodermal Tumor

Genes related to Intracranial Primitive Neuroectodermal Tumor (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CD99	CD99 Molecule (Xg Blood Group)	Protein Coding	7.06	DISEASES inferred ¹⁴
2	FLI1	Fli-1 Proto-Oncogene, ETS Transcription Factor	Protein Coding	5.31	DISEASES inferred ¹⁴
3	EWSR1	EWS RNA Binding Protein 1	Protein Coding	5.2	DISEASES inferred ¹⁴
4	SCG2	Secretogranin II	Protein Coding	5.17	DISEASES inferred ¹⁴
5	CENPV	Centromere Protein V	Protein Coding	5.08	DISEASES inferred ¹⁴
6	ENO2	Enolase 2	Protein Coding	5.05	DISEASES inferred ¹⁴
7	SYP	Synaptophysin	Protein Coding	4.96	DISEASES inferred ¹⁴
8	RASSF1	Ras Association Domain Family Member 1	Protein Coding	4.74	DISEASES inferred ¹⁴

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Variations for Intracranial Primitive Neuroectodermal Tumor

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Expression for Intracranial Primitive Neuroectodermal Tumor

Search GEO for disease gene expression data for Intracranial Primitive Neuroectodermal Tumor.

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Pathways for Intracranial Primitive Neuroectodermal Tumor

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GO Terms for Intracranial Primitive Neuroectodermal Tumor

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Sources for Intracranial Primitive Neuroectodermal Tumor

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

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¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: INT022 MIFTS: 19	Intracranial Primitive Neuroectodermal Tumor Categories: Cancer diseases, Neuronal diseases, Skin diseases	Data Licensing For inquiries, contact: [email protected]
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