MCID: INT022
MIFTS: 19

Intracranial Primitive Neuroectodermal Tumor

Categories: Cancer diseases, Neuronal diseases

Aliases & Classifications for Intracranial Primitive Neuroectodermal Tumor

MalaCards integrated aliases for Intracranial Primitive Neuroectodermal Tumor:

Name: Intracranial Primitive Neuroectodermal Tumor 12 15
Intracranial Primitive Neuroectodermal Neoplasm 73
Intracranial Pnet 12

Classifications:



External Ids:

Disease Ontology 12 DOID:4788
NCIt 50 C5817
UMLS 73 C1334246

Summaries for Intracranial Primitive Neuroectodermal Tumor

MalaCards based summary : Intracranial Primitive Neuroectodermal Tumor, also known as intracranial primitive neuroectodermal neoplasm, is related to ureter small cell carcinoma and urinary bladder small cell neuroendocrine carcinoma. An important gene associated with Intracranial Primitive Neuroectodermal Tumor is SCG2 (Secretogranin II). Related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

Related Diseases for Intracranial Primitive Neuroectodermal Tumor

Diseases related to Intracranial Primitive Neuroectodermal Tumor via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 ureter small cell carcinoma 10.1 CHGA ENO2
2 urinary bladder small cell neuroendocrine carcinoma 10.1 CHGA ENO2
3 auditory system cancer 10.1 CHGA ENO2
4 gallbladder small cell carcinoma 10.1 CHGA ENO2
5 small cell carcinoma of the bladder 10.1 CHGA ENO2
6 epithelioid malignant peripheral nerve sheath tumor 10.1 CHGA ENO2
7 pulmonary large cell neuroendocrine carcinoma 10.1 CHGA ENO2
8 atypical follicular adenoma 10.1 CHGA ENO2
9 goblet cell carcinoid 10.1 CHGA ENO2
10 olfactory nerve neoplasm 10.1 CHGA ENO2
11 cauda equina neoplasm 10.1 CHGA ENO2
12 acute thyroiditis 10.1 CHGA ENO2
13 nodular ganglioneuroblastoma 10.1 CHGA ENO2
14 pineocytoma 10.1 CHGA ENO2
15 respiratory system benign neoplasm 10.1 CHGA ENO2
16 gastric squamous cell carcinoma 10.1 CHGA ENO2
17 gastric small cell carcinoma 10.1 CHGA ENO2
18 collagenous colitis 10.1 CHGA SCG2
19 subependymoma 10.1 CHGA ENO2
20 carcinoid tumors, intestinal 10.1 CHGA ENO2
21 somatostatinoma 10.1 CHGA ENO2
22 papillary ependymoma 10.1 CHGA ENO2
23 duodenal gastrinoma 10.1 CHGA ENO2
24 sclerosing hemangioma 10.1 CHGA ENO2
25 central neurocytoma 10.1 CHGA ENO2
26 carcinoid syndrome 10.1 CHGA ENO2
27 spinal meningioma 10.1 CHGA ENO2
28 spinal canal and spinal cord meningioma 10.1 CHGA ENO2
29 cranial nerve malignant neoplasm 10.0 CHGA ENO2
30 cervix small cell carcinoma 10.0 CHGA ENO2
31 olfactory neuroblastoma 10.0 CHGA ENO2
32 diffuse pulmonary fibrosis 10.0 CHGA ENO2
33 cerebellar liponeurocytoma 10.0 CHGA ENO2
34 horseshoe kidney 10.0 CHGA ENO2
35 granulosa cell tumor of the ovary 10.0 CHGA ENO2
36 large cell neuroendocrine carcinoma 10.0 CHGA ENO2
37 mixed ductal-endocrine carcinoma 10.0 CHGA ENO2
38 ewing's family of tumors 10.0
39 ganglioneuroma 9.9 CHGA ENO2
40 lung benign neoplasm 9.9 CHGA ENO2
41 ganglioglioma 9.9 CHGA ENO2
42 small cell carcinoma 9.9 CHGA ENO2
43 kidney rhabdoid cancer 9.9 CD99 ENO2
44 large cell carcinoma 9.9 CHGA ENO2
45 breast adenomyoepithelioma 9.9 CD99 ENO2
46 breast myoepithelial neoplasm 9.8 CD99 ENO2
47 merkel cell carcinoma 9.8 CHGA ENO2
48 extraskeletal ewing sarcoma 9.8 CD99 ENO2
49 paraganglioma 9.8 CHGA ENO2
50 pericardium cancer 9.8 CD99 ENO2

Graphical network of the top 20 diseases related to Intracranial Primitive Neuroectodermal Tumor:



Diseases related to Intracranial Primitive Neuroectodermal Tumor

Symptoms & Phenotypes for Intracranial Primitive Neuroectodermal Tumor

GenomeRNAi Phenotypes related to Intracranial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-10 9.61 CD99
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-181 9.61 CD99
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-20 9.61 CD99
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-213 9.61 CD99
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-53 9.61 CHGA
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-61 9.61 CD99 CHGA
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-65 9.61 CHGA
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-91 9.61 CD99
9 Decreased viability of wild-type and TP53 knockout cells, decreased TP53 protein expression ratio (wild-type / TP53 knockout cells) GR00196-A-1 8.8 CENPV CHGA SCG2

Drugs & Therapeutics for Intracranial Primitive Neuroectodermal Tumor

Search Clinical Trials , NIH Clinical Center for Intracranial Primitive Neuroectodermal Tumor

Genetic Tests for Intracranial Primitive Neuroectodermal Tumor

Anatomical Context for Intracranial Primitive Neuroectodermal Tumor

Publications for Intracranial Primitive Neuroectodermal Tumor

Articles related to Intracranial Primitive Neuroectodermal Tumor:

# Title Authors Year
1
Promoter hypermethylation profile of RASSF1A, FHIT, and sFRP1 in intracranial primitive neuroectodermal tumors. ( 16311119 )
2005

Variations for Intracranial Primitive Neuroectodermal Tumor

Expression for Intracranial Primitive Neuroectodermal Tumor

Search GEO for disease gene expression data for Intracranial Primitive Neuroectodermal Tumor.

Pathways for Intracranial Primitive Neuroectodermal Tumor

GO Terms for Intracranial Primitive Neuroectodermal Tumor

Cellular components related to Intracranial Primitive Neuroectodermal Tumor according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 secretory granule GO:0030141 8.62 CHGA SCG2

Sources for Intracranial Primitive Neuroectodermal Tumor

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7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
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49 NCI
50 NCIt
51 NDF-RT
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58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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