MCID: INT076
MIFTS: 20

Intracranial Sinus Thrombosis

Categories: Blood diseases, Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Intracranial Sinus Thrombosis

MalaCards integrated aliases for Intracranial Sinus Thrombosis:

Name: Intracranial Sinus Thrombosis 12 15
Sinus Thrombosis, Intracranial 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:3572
MeSH 44 D012851
UMLS 73 C0037198

Summaries for Intracranial Sinus Thrombosis

MalaCards based summary : Intracranial Sinus Thrombosis, also known as sinus thrombosis, intracranial, is related to sagittal sinus thrombosis and thrombosis. An important gene associated with Intracranial Sinus Thrombosis is RHNO1 (RAD9-HUS1-RAD1 Interacting Nuclear Orphan 1). The drugs Warfarin and Apixaban have been mentioned in the context of this disorder.

Related Diseases for Intracranial Sinus Thrombosis

Diseases related to Intracranial Sinus Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 20)
# Related Disease Score Top Affiliating Genes
1 sagittal sinus thrombosis 29.8 BLVRA SERPINC1
2 thrombosis 10.3
3 orbital disease 10.0 PGBD1 RHNO1
4 orbital cellulitis 9.9 PGBD1 RHNO1
5 branch retinal artery occlusion 9.9 RHNO1 SERPINC1
6 cranial nerve palsy 9.9 NT5C3A RHNO1
7 skull base cancer 9.9 BLVRA NT5C3A
8 skull base meningioma 9.9 BLVRA NT5C3A
9 stroke, ischemic 9.8
10 anorexia nervosa 9.8
11 abdominal tuberculosis 9.8
12 aseptic meningitis 9.8
13 homocystinuria 9.8
14 intracranial hypertension 9.8
15 meningitis 9.8
16 thunderclap headache 9.8
17 headache 9.8
18 acute orbital inflammation 9.8 PGBD1 RHNO1
19 petroclival meningioma 9.8 BLVRA NT5C3A
20 cavernous sinus thrombosis 9.6 NT5C3A PGBD1 RHNO1 SERPINC1

Graphical network of the top 20 diseases related to Intracranial Sinus Thrombosis:



Diseases related to Intracranial Sinus Thrombosis

Symptoms & Phenotypes for Intracranial Sinus Thrombosis

Drugs & Therapeutics for Intracranial Sinus Thrombosis

Drugs for Intracranial Sinus Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 42)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Warfarin Approved Phase 3 81-81-2 6691 54678486
2
Apixaban Approved Phase 3 503612-47-3 10182969
3
Heparin Approved, Investigational Phase 2, Phase 3 9005-49-6 772 46507594
4
Dalteparin Approved Phase 2, Phase 3 9005-49-6
5
Serine Approved, Nutraceutical Phase 3 56-45-1 5951
6
protease inhibitors Phase 3
7 Anticoagulants Phase 3,Phase 2
8 Antithrombin III Phase 3
9 HIV Protease Inhibitors Phase 3
10 Antithrombins Phase 3
11 Dabigatran Phase 3
12 Serine Proteinase Inhibitors Phase 3
13 Pharmaceutical Solutions Phase 3
14 Factor Xa Inhibitors Phase 3
15
asparaginase Phase 3
16 Tissue Plasminogen Activator Phase 2, Phase 3
17 Calcium, Dietary Phase 2, Phase 3
18 calcium heparin Phase 2, Phase 3
19 Plasminogen Phase 2, Phase 3
20 Fibrinolytic Agents Phase 2, Phase 3
21 Heparin, Low-Molecular-Weight Phase 2, Phase 3
22 Hematinics Phase 1, Phase 2
23 Epoetin alfa Phase 1, Phase 2 113427-24-0
24
Estradiol Approved, Investigational, Vet_approved 50-28-2 5757
25
Levonorgestrel Approved, Investigational 17489-40-6, 797-63-7 13109
26
Ethinyl Estradiol Approved 57-63-6 5991
27 Estradiol valerate Approved, Investigational, Vet_approved 979-32-8
28
Norelgestromin Approved, Investigational 53016-31-2 13752005
29
Polyestradiol phosphate Approved 28014-46-2
30 Estradiol 17 beta-cypionate
31 Estradiol 3-benzoate
32 Estrogens
33 Contraceptives, Oral
34 Contraceptive Agents
35 Contraceptives, Oral, Combined
36 Ortho Evra
37 Hormones, Hormone Substitutes, and Hormone Antagonists
38 Hormones
39 Hormone Antagonists
40 Ethinyl estradiol, levonorgestrel drug combination
41 Norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination
42 Norinyl

Interventional clinical trials:

(show all 14)
# Name Status NCT ID Phase Drugs
1 A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis (RE-SPECT CVT) Completed NCT02913326 Phase 3 Dabigatran etexilate;Warfarin
2 A Study of the Safety and Effectiveness of Apixaban in Preventing Blood Clots in Children With Leukemia Who Have a Central Venous Catheter and Are Treated With Asparaginase Recruiting NCT02369653 Phase 3 Apixaban
3 The Efficacy and Safety of Dabigatran Etexilate for the Treatment of Cerebral Venous Thrombosis Recruiting NCT03217448 Phase 3 Dabigatran etexilate;Warfarin
4 Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis Terminated NCT01204333 Phase 2, Phase 3 Endovascular thrombolysis;Heparin
5 Erythropoetin Neuroprotection for Neonatal Cardiac Surgery Unknown status NCT00513240 Phase 1, Phase 2 Erythropoetin;Normal saline
6 Wrinkle Injection With Autologous Platelet Rich Plasma Study Withdrawn NCT01078493 Phase 1
7 Fast Magnetic Resonance Imaging as Compared to Computed Tomography Scan in Pediatric Orbital Cellulitis Imaging Unknown status NCT02711436 Not Applicable
8 Relative Risks for Non-fatal Venous Thromboembolism, Ischemic Stroke and Myocardial Infarction in Users of ORTHO EVRA(Norelgestromin and Ethinyl Estradiol Contraceptive Patch) Compared to Levonorgestrel-containing Oral Contraceptives. Completed NCT00511784
9 Study Of Lybrel In Relation To Venous Thromboembolism Completed NCT01297348 90ug levonorgestrel / 20 ug ethinyl estradiol;Oral Contraceptives containing 20 ug of ethinyl estradiol
10 Comparison of the Radiological Pattern Between the Cerebral Stroke of Arterial and Venous Origin Completed NCT03611894
11 Impact of Cranioplasty On Cerebral Perfusion Completed NCT01113645
12 Cerebral Venous Sinus Thrombosis: Re-exploration of Clinical Assessment Scales Recruiting NCT03273179
13 CONNECT-ME: Consciousness in Neurocritical Care Cohort Study Using fMRI and EEG Recruiting NCT02644265
14 Stroke and Cerebrovascular Diseases Registry Recruiting NCT03281590

Search NIH Clinical Center for Intracranial Sinus Thrombosis

Cochrane evidence based reviews: sinus thrombosis, intracranial

Genetic Tests for Intracranial Sinus Thrombosis

Anatomical Context for Intracranial Sinus Thrombosis

Publications for Intracranial Sinus Thrombosis

Articles related to Intracranial Sinus Thrombosis:

# Title Authors Year
1
A Case of Deep Vein Thrombosis and Intracranial Sinus Thrombosis: Possible rare complications of childhood abdominal tuberculosis. ( 28003904 )
2016
2
WITHDRAWN: Intracranial Sinus Thrombosis in Anorexia Nervosa. ( 20659740 )
2010
3
Successful management of an extensive intracranial sinus thrombosis in a patient undergoing IVF: case report and review of literature. ( 17349640 )
2007
4
Aseptic meningitis, venous sinus thrombosis, intracranial hypertension and callosal involvement contemporaneously in a young patient with BehAset's disease. ( 16453209 )
2005
5
Thunderclap headache: presentation of intracranial sinus thrombosis? ( 12887960 )
2003
6
Intracranial sinus thrombosis in a patient with Crohn disease and factor V Leiden mutation. ( 12873183 )
2003
7
Intracranial sinus thrombosis secondary to ear disease in an adolescent. ( 9176806 )
1997
8
Open thrombectomy combined with thrombolysis in massive intracranial sinus thrombosis. ( 7847137 )
1994
9
Cerebral infarction due to intracranial sinus thrombosis. ( 5835445 )
1965

Variations for Intracranial Sinus Thrombosis

Expression for Intracranial Sinus Thrombosis

Search GEO for disease gene expression data for Intracranial Sinus Thrombosis.

Pathways for Intracranial Sinus Thrombosis

GO Terms for Intracranial Sinus Thrombosis

Sources for Intracranial Sinus Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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