MCID: INT078
MIFTS: 48

Intracranial Thrombosis

Categories: Blood diseases, Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Intracranial Thrombosis

MalaCards integrated aliases for Intracranial Thrombosis:

Name: Intracranial Thrombosis 12 45 15 74
Cerebral Thrombosis 12 77 56 74
Thrombosis of Cerebral Veins 74
Cerebral Arterial Thrombosis 74

Classifications:



External Ids:

Disease Ontology 12 DOID:4193
ICD9CM 36 434.0
MeSH 45 D020767

Summaries for Intracranial Thrombosis

MalaCards based summary : Intracranial Thrombosis, also known as cerebral thrombosis, is related to heparin-induced thrombocytopenia and factor xiii deficiency. An important gene associated with Intracranial Thrombosis is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Response to elevated platelet cytosolic Ca2+ and Collagen chain trimerization. The drugs Epoetin alfa and Hematinics have been mentioned in the context of this disorder. Affiliated tissues include heart, placenta and brain, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 77 A thrombus, colloquially called a blood clot, is the final product of the blood coagulation step in... more...

Related Diseases for Intracranial Thrombosis

Diseases related to Intracranial Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 190)
# Related Disease Score Top Affiliating Genes
1 heparin-induced thrombocytopenia 30.0 F3 SERPINC1
2 factor xiii deficiency 29.6 F3 F5 F8
3 protein c deficiency 29.6 F5 MTHFR SERPINC1
4 homocystinuria 29.6 F5 MTHFR SERPINC1
5 intracranial embolism 29.5 PLG SERPINC1
6 thrombocytopenia 29.5 APOH F3 ITGA2B
7 protein s deficiency 29.4 APOH F3 F5 MTHFR SERPINC1
8 antithrombin iii deficiency 29.4 APOH F5 MTHFR SERPINC1
9 placental abruption 29.4 APOH F5 MTHFR SERPINC1
10 thrombosis 28.8 APOH F3 F5 F8 MTHFR SERPINC1
11 heart disease 28.8 F3 F8 MTHFR SERPINC1 VWF
12 acute myocardial infarction 28.7 F3 ITGA2B PLG SERPINC1 VWF
13 antiphospholipid syndrome 28.7 APOH F3 F5 MTHFR SERPINC1 VWF
14 pulmonary embolism 28.7 APOH F3 F5 MTHFR SERPINC1 VWF
15 myocardial infarction 27.1 F3 F5 F8 FGA ITGA2B MTHFR
16 may-thurner syndrome 10.4 APOH F5
17 sticky platelet syndrome 10.4 F5 SERPINC1
18 acanthamoeba keratitis 10.4 APOH F5
19 pregnancy loss, recurrent 1 10.3 APOH F5
20 sneddon syndrome 10.3 APOH SERPINC1
21 meningococcemia 10.3 F5 SERPINC1
22 platelet aggregation, spontaneous 10.3 SERPINC1 VWF
23 purpura fulminans 10.3 F3 SERPINC1
24 breast reconstruction 10.3 APOH F8
25 factor v and factor viii, combined deficiency of, 2 10.3 F5 F8
26 qualitative platelet defect 10.3 F3 VWF
27 arteritic anterior ischemic optic neuropathy 10.3 F5 MTHFR
28 inferior vena cava interruption 10.2 F5 MTHFR
29 aspirin allergy 10.2 ITGA2B SERPINC1
30 amaurosis fugax 10.2 F5 MTHFR
31 prothrombin deficiency, congenital 10.2 APOH F5 SERPINC1
32 ischemic colitis 10.2 APOH F5 SERPINC1
33 raynaud phenomenon 10.2 APOH VWF
34 fainting 10.2 F8 VWF
35 legg-calve-perthes disease 10.2 APOH F5 SERPINC1
36 alcohol-related birth defect 10.2 F3 F8
37 sagittal sinus thrombosis 10.2 F3 F5 SERPINC1
38 cryptogenic cirrhosis 10.2 F5 MTHFR
39 pulmonary immaturity 10.2 F3 SERPINC1
40 severe pre-eclampsia 10.2 APOH F5 SERPINC1
41 porencephaly 10.2 F5 MTHFR
42 factor xi deficiency 10.2 F3 SERPINC1
43 cerebral sinovenous thrombosis 10.2 APOH F3 F5
44 acquired von willebrand syndrome 10.2 F8 VWF
45 dysfibrinogenemia 10.2 F5 FGA SERPINC1
46 brachydactyly, type d 10.2 F8 VWF
47 carotid artery thrombosis 10.2 F3 ITGA2B
48 hemarthrosis 10.2 F8 VWF
49 angina pectoris 10.2 FGA SERPINC1
50 behcet syndrome 10.2 APOH F5 SERPINC1

Comorbidity relations with Intracranial Thrombosis via Phenotypic Disease Network (PDN): (show all 21)


Active Peptic Ulcer Disease Acute Cystitis
Aortic Valve Disease 1 Benign Essential Hypertension
Cerebral Atherosclerosis Cerebrovascular Disease
Chronic Myocardial Ischemia Decubitus Ulcer
Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation Familial Atrial Fibrillation
Generalized Atherosclerosis Heart Disease
Hypertension, Essential Intracranial Embolism
Ischemic Heart Disease Malignant Essential Hypertension
Peripheral Vascular Disease Schizophreniform Disorder
Spastic Hemiplegia Swallowing Disorders
Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Intracranial Thrombosis:



Diseases related to Intracranial Thrombosis

Symptoms & Phenotypes for Intracranial Thrombosis

MGI Mouse Phenotypes related to Intracranial Thrombosis:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.02 APOH F3 F5 F8 FGA ITGA2B
2 cardiovascular system MP:0005385 9.95 F3 F5 FGA ITGA2B PLG SERPINC1
3 hematopoietic system MP:0005397 9.91 F3 F8 FGA ITGA2B PLG SERPINC1
4 immune system MP:0005387 9.86 F3 F8 FGA ITGA2B PLA2G7 PLG
5 mortality/aging MP:0010768 9.65 APOH F3 F5 F8 FGA MTHFR
6 liver/biliary system MP:0005370 9.55 F5 FGA MTHFR PLG SERPINC1
7 reproductive system MP:0005389 9.1 F8 FGA ITGA2B MTHFR PLG SERPINC1

Drugs & Therapeutics for Intracranial Thrombosis

Drugs for Intracranial Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 68)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Epoetin alfa Phase 4 113427-24-0
2 Hematinics Phase 4
3
Warfarin Approved Phase 3,Phase 2,Phase 1,Not Applicable 81-81-2 54678486 6691
4
Acenocoumarol Approved, Investigational Phase 3 152-72-7 54676537 9052
5
Rivaroxaban Approved Phase 3,Phase 2,Phase 1,Not Applicable 366789-02-8
6
Tranexamic Acid Approved Phase 3 1197-18-8 5526
7
Apixaban Approved Phase 3,Not Applicable 503612-47-3 10182969
8
Dalteparin Approved Phase 3,Phase 2 9005-49-6
9
Heparin Approved, Investigational Phase 3,Phase 2,Not Applicable 9005-49-6 46507594 772
10
Tenecteplase Approved Phase 3 191588-94-0
11
tannic acid Approved Phase 2, Phase 3 1401-55-4
12
Benzocaine Approved, Investigational Phase 2, Phase 3 1994-09-7, 94-09-7 2337
13
Serine Approved, Nutraceutical Phase 3,Phase 2,Phase 1 56-45-1 5951
14
Calcium Approved, Nutraceutical Phase 2, Phase 3 7440-70-2 271
15
Dabigatran Investigational Phase 3,Not Applicable 211914-51-1
16 HIV Protease Inhibitors Phase 3,Phase 2,Phase 1
17 Serine Proteinase Inhibitors Phase 3,Phase 2,Phase 1
18
protease inhibitors Phase 3,Phase 2,Phase 1
19 Antithrombin III Phase 3,Phase 2,Phase 1
20 Anticoagulants Phase 3,Phase 2,Phase 1,Not Applicable
21 Antithrombins Phase 3,Phase 2,Phase 1
22 Factor Xa Inhibitors Phase 3,Phase 2,Phase 1
23 Coagulants Phase 3
24 Hemostatics Phase 3,Not Applicable
25 Antifibrinolytic Agents Phase 3
26 Fibrinolytic Agents Phase 3,Phase 2
27 calcium heparin Phase 3,Phase 2,Not Applicable
28 Heparin, Low-Molecular-Weight Phase 3,Phase 2
29 Calcium, Dietary Phase 2, Phase 3
30 Plasminogen Inactivators Phase 3
31 Tissue Plasminogen Activator Phase 3,Phase 2
32 Plasminogen Phase 3,Phase 2
33
Phylloquinone Approved, Investigational Phase 2 84-80-0
34 Menaquinone Approved, Investigational Phase 2 1182-68-9
35
Tinzaparin Approved Phase 2 9041-08-1, 9005-49-6 25244225
36
Enoxaparin Approved Phase 2,Phase 1 9005-49-6 772
37
Menadione Approved, Nutraceutical Phase 2 58-27-5 4055
38
asparaginase Phase 2
39 Vitamins Phase 2
40 naphthoquinone Phase 2
41 Vitamin K Phase 2
42
Triamcinolone Approved, Vet_approved 124-94-7 31307
43
Ethinyl Estradiol Approved 57-63-6 5991
44
Levonorgestrel Approved, Investigational 797-63-7, 17489-40-6 13109
45
Polyestradiol phosphate Approved 28014-46-2
46
Estradiol Approved, Investigational, Vet_approved 50-28-2 5757
47
Thrombin Approved, Investigational
48
Edoxaban Approved ,Not Applicable 480449-70-5
49
Metronidazole Approved 443-48-1 4173
50
Aspirin Approved, Vet_approved 50-78-2 2244

Interventional clinical trials:

(show all 42)
# Name Status NCT ID Phase Drugs
1 A Safety Study of Epoetin Alfa in Patients With Cancer Who Have Chemotherapy-Related Anemia Completed NCT01394991 Phase 4 Epoetin alfa 450 IU/kg once a week;Epoetin alfa 150 IU/kg 3 times a week;Epoetin alfa 450 IU/kg once a week (QW);Epoetin alfa 150 IU/kg 3 times a week (TIW)
2 A Clinical Trial Comparing Efficacy and Safety of Dabigatran Etexilate With Warfarin in Patients With Cerebral Venous and Dural Sinus Thrombosis (RE-SPECT CVT) Completed NCT02913326 Phase 3 Dabigatran etexilate;Warfarin
3 Rivaroxaban for Patients With Antiphospholipid Syndrome Completed NCT02926170 Phase 3 Rivaroxaban;acenocumarol
4 Safety Study of XP12B in Women With Menorrhagia Completed NCT00113568 Phase 3 Tranexamic acid tablets (XP12B)
5 The Efficacy and Safety of Dabigatran Etexilate for the Treatment of Cerebral Venous Thrombosis Recruiting NCT03217448 Phase 3 Dabigatran etexilate;Warfarin
6 Apixaban in Preventing Secondary Cancer Related Blood Clots in Cancer Patients Who Have Completed Anticoagulation Therapy Recruiting NCT03080883 Phase 3 Apixaban
7 Apixaban or Dalteparin in Reducing Blood Clots in Patients With Cancer Related Venous Thromboembolism Active, not recruiting NCT02585713 Phase 3 Apixaban;Dalteparin
8 Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke Not yet recruiting NCT03889249 Phase 3 Tenecteplase;Alteplase
9 RIvaroxaban for Stroke Patients With AntiPhospholipid Syndrome Not yet recruiting NCT03684564 Phase 2, Phase 3 Rivaroxaban;Warfarin
10 Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis Terminated NCT01204333 Phase 2, Phase 3 Endovascular thrombolysis;Heparin
11 Administration of GRASPA (Suspension of Erythrocytes Encapsulating L-asparaginase) in Elderly Patients With First Line Acute Lymphoblastic Leukemia Completed NCT01523782 Phase 2 GRASPA
12 Study of Rivaroxaban for CeREbral Venous Thrombosis Recruiting NCT03178864 Phase 2 Rivaroxaban;Standard of care
13 Efficacy Comparison of Warfarin Versus Rivaroxaban CVT Recruiting NCT03747081 Phase 1, Phase 2 Rivaroxaban;Warfarin
14 Prevention for the Restenosis of Intracranial Artery Stent Implantation Treated With Herbal Medicine C117 Not yet recruiting NCT03008798 Phase 2 Herbal Medicine C-117;The Placebo of Herbal Medicine C-117
15 A Trial of Clay Weight on the Ear Drum for Patulous Eustachian Tube Unknown status NCT00933478
16 Modern Ultrasound Techniques in the Evaluation of Cerebral Venous Sinuses in Neonates Completed NCT00555932 Not Applicable
17 Study Of Lybrel In Relation To Venous Thromboembolism Completed NCT01297348 90ug levonorgestrel / 20 ug ethinyl estradiol;Oral Contraceptives containing 20 ug of ethinyl estradiol
18 Impact of Cranioplasty On Cerebral Perfusion Completed NCT01113645
19 Otogenic CSVT Retrospective Case Series and Associated Thrombophilia Completed NCT03864055
20 Comparison of the Radiological Pattern Between the Cerebral Stroke of Arterial and Venous Origin Completed NCT03611894
21 Thrombin Generation and Thrombus Degradation in Cerebral Venous Thrombosis : Clinical and Radiological Correlations Completed NCT02013635
22 Evaluation of Cerebral Oxygenation and Hemodynamics in Patients With Cerebral Venous Thrombosis Completed NCT03033966
23 The Role of Factor XIII Activation Peptide and D-dimer Values for the Diagnosis of Cerebral Venous Thrombosis (CVT) Completed NCT00924859
24 Cyanotic Heart Disease and Thrombosis Completed NCT02716402 Not Applicable
25 Intracranial Hypertension and Optic Nerve Sheath Diameter Completed NCT01796015 Not Applicable
26 Multimodal Monitoring in Patients With Spontaneous Intracerebral Hemorrhage Completed NCT02326571
27 Body Composition Monitor(BCM) Guided Fluid Management in Maintenance Hemodialysis (MHD) Patients Completed NCT01509937 Not Applicable
28 Intracranial Thrombosis Aspiration Catheter for Recanalization in Acute Ischemic Stroke Therapy (RECOVER) Recruiting NCT03753061 Not Applicable
29 Stroke and Cerebrovascular Diseases Registry Recruiting NCT03281590
30 Cerebral Venous Sinus Thrombosis: Re-exploration of Clinical Assessment Scales Recruiting NCT03273179
31 Paroxysmal Nocturnal Hemoglobinuria in ESUS & ETUS Recruiting NCT03329365
32 Registry of Patients Prescribed Anticoagulation Recruiting NCT03504007
33 Searching for Explanations for Cryptogenic Stroke in the Young: Revealing the Etiology, Triggers, and Outcome Recruiting NCT01934725
34 Stroke in Egyptian Clinical REgisTry Recruiting NCT03723382
35 Venous Sinus Stenting With the River Stent in IIH Recruiting NCT03556085 Not Applicable
36 Prediction of Preeclampsia by Comprehensive Markers. Recruiting NCT03665623
37 Cerebral Venous Thrombosis Cohort Study in China Mainland Not yet recruiting NCT03919305
38 Comparison of the Efficacy of Rivroxaban to Coumadin( Warfarin ) in Cerebral Venous Thrombosis Not yet recruiting NCT03191305 Not Applicable Coumadin;Rivoroxaban
39 DOAC in Unusual Site Venous Thrombosis Not yet recruiting NCT03778502 Direct Oral Anticoagulants
40 OPTIMAS: OPtimal TIMing of Anticoagulation After Acute Ischaemic Stroke : a Randomised Controlled Trial Not yet recruiting NCT03759938 Not Applicable Direct oral anticoagulant (DOAC)
41 LAmbre™ Left Atrial Appendage Closure System Follow-Up Study Not yet recruiting NCT03693092
42 Maintaining a Prone Position After Use of an Epidural Blood Patch for the Treatment of Post-dural Puncture Headache Terminated NCT02427009 Not Applicable

Search NIH Clinical Center for Intracranial Thrombosis

Cochrane evidence based reviews: intracranial thrombosis

Genetic Tests for Intracranial Thrombosis

Anatomical Context for Intracranial Thrombosis

MalaCards organs/tissues related to Intracranial Thrombosis:

42
Heart, Placenta, Brain, Testes, Endothelial, Spinal Cord

Publications for Intracranial Thrombosis

Articles related to Intracranial Thrombosis:

(show top 50) (show all 183)
# Title Authors Year
1
Early diagnosis of cerebral thrombosis by EGFP-EGF1 protein conjugated ferroferric oxide magnetic nanoparticles. ( 30646803 )
2019
2
Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study. ( 29427117 )
2018
3
Heterozygous FGA p.Asp473Ter (fibrinogen Nieuwegein) presenting as antepartum cerebral thrombosis. ( 29122299 )
2018
4
GPVI‑Fc‑PEG improves cerebral infarct volume and cerebral thrombosis in mouse model with cerebral thrombosis. ( 28944903 )
2017
5
Cerebral Thrombosis: A Neurogenetic Approach. ( 28971443 )
2017
6
Effect of Melilotus officinalis extract on the apoptosis of brain tissues by altering cerebral thrombosis and inflammatory mediators in acute cerebral ischemia. ( 28320101 )
2017
7
Evaluation of cases with cerebral thrombosis in children. ( 27489465 )
2016
8
Partial distal aphalangia, duplication of metatarsal IV, microcephaly, and borderline intelligence: a fourth patient with parental consanguinity and additional feature of massive cerebral thrombosis. ( 25304118 )
2015
9
Acute Cerebral Thrombosis Following Ovarian Hyperstimulation Syndrome: A Case Report. ( 26668156 )
2015
10
Successful thrombolysis following enoxaparin therapy in two pediatric patients with congenital heart disease presenting with intracardiac and cerebral thrombosis. ( 25278813 )
2014
11
Role of inflammatory parameters in the susceptibility of cerebral thrombosis. ( 24782217 )
2014
12
Cerebral thrombosis and myeloproliferative neoplasms. ( 25217248 )
2014
13
Delayed cerebral thrombosis in bacterial meningitis: a prospective cohort study. ( 23248040 )
2013
14
Incompletely Evaluated ART Leading to Ectopic Pregnancy and Cerebral Thrombosis. ( 24520477 )
2013
15
An 8-year follow-up of a patient with acute myocardial infarction complicated with ventricular rupture and cerebral thrombosis treated conservatively: a cohort study. ( 23531927 )
2013
16
Cerebral thrombosis in patients with β-thalassemia: a systematic review. ( 22322139 )
2012
17
Thrombolytic effects of a combined therapy with targeted microbubbles and ultrasound in a 6 h cerebral thrombosis rabbit model. ( 22016106 )
2012
18
Preventive effects of hesperidin, glucosyl hesperidin and naringin on hypertension and cerebral thrombosis in stroke-prone spontaneously hypertensive rats. ( 22228501 )
2012
19
Pulsatile tinnitus and venous cerebral thrombosis: report of a case and literature review. ( 23590107 )
2012
20
Cerebral thrombosis in inflammatory bowel disease: a report of four cases. ( 21575890 )
2011
21
Cerebral thrombosis complicating Crohn's disease: two cases. ( 22078296 )
2011
22
Delayed cerebral thrombosis after initial good recovery from pneumococcal meningitis: past as prologue: delayed stroke as a parainfectious process of bacterial meningitis? ( 20625175 )
2010
23
Delayed cerebral thrombosis after initial good recovery from pneumococcal meningitis. ( 19890068 )
2009
24
Correspondence between neurological deficit, cerebral infarct size, and Rho-kinase activity in a rat cerebral thrombosis model. ( 19165632 )
2009
25
AbetaPP/APLP2 family of Kunitz serine proteinase inhibitors regulate cerebral thrombosis. ( 19403832 )
2009
26
Wide therapeutic time window for Rho-kinase inhibition therapy in ischemic brain damage in a rat cerebral thrombosis model. ( 18187127 )
2008
27
Cerebral thrombosis in systemic lupus erythematosus with the antibody antiphospholipid syndrome. ( 17485792 )
2007
28
Cerebral thrombosis associated with heterozygous factor V Leiden mutation and high lipoprotein(a) level in a girl with factor XIII deficiency. ( 17473580 )
2007
29
Congenital hypodysfibrinogenemia and abruptio placentae in a woman with history of cerebral thrombosis. ( 17364292 )
2007
30
Significance of factor V, prothrombin, MTHFR, and PAI-1 genotypes in childhood cerebral thrombosis. ( 17456624 )
2007
31
Improving effect of Ginkgolide B on mitochondrial respiration of ischemic neuron after cerebral thrombosis in tree shrewa. ( 17908463 )
2007
32
Carotid atherosclerosis and arterial peripheral pulse wave velocity in cerebral thrombosis. ( 16410196 )
2006
33
Extension of intracranial thrombosis after unilateral dissection of the internal jugular vein. ( 15897422 )
2005
34
Cerebral thrombosis in a postmenopausal woman on HRT. ( 15639431 )
2005
35
Cerebral thrombosis in childhood nephrosis. ( 15813879 )
2005
36
Protease nexin-2/amyloid beta-protein precursor limits cerebral thrombosis. ( 16330760 )
2005
37
Effects of the lifting manipulation of scalp acupuncture for raising myodynamia of the affected limbs in hemiplegic patients due to cerebral thrombosis. ( 16447664 )
2005
38
Effects of voluntary exercise on cerebral thrombosis and endothelial function in spontaneously hypertensive rats (SHRSP/Izm). ( 15649288 )
2004
39
Delayed-onset heparin-induced thrombocytopenia and cerebral thrombosis after a single administration of unfractionated heparin. ( 12637624 )
2003
40
Cerebral thrombosis and microcirculation of the rat during the oestrous cycle and after ovariectomy. ( 11906462 )
2002
41
Contraceptives and cerebral thrombosis: a five-year national case-control study. ( 11929641 )
2002
42
Effects of Ginkgo biloba extract (EGb 761) on cerebral thrombosis and blood pressure in stroke-prone spontaneously hypertensive rats. ( 12366386 )
2002
43
Prothrombotic factors in neonates with cerebral thrombosis and intraventricular hemorrhage. ( 12477269 )
2002
44
Clinical observation on influence of chinese medicines for promoting blood circulation to remove blood stasis on FIB and DD in plasma of patients with cerebral thrombosis. ( 16579084 )
2002
45
Cerebral thrombosis in beta-thalassaemia major. ( 11770248 )
2001
46
A case with cerebral thrombosis receiving tamoxifen treatment. ( 11784361 )
2001
47
The regional cerebral blood flow amelioration of argatroban in the acute stage of cerebral thrombosis. ( 10750366 )
2000
48
Cerebral thrombosis and vasculitis: an uncommon complication of ulcerative colitis. ( 10846281 )
2000
49
Neoplastic cerebral aneurysm from metastatic lung adenocarcinoma associated with cerebral thrombosis and recurrent subarachnoid haemorrhage. ( 10071112 )
1999
50
Cerebrovascular acetazolamide reactivity and platelet function in asymptomatic cerebral thrombosis. ( 10475099 )
1999

Variations for Intracranial Thrombosis

Expression for Intracranial Thrombosis

Search GEO for disease gene expression data for Intracranial Thrombosis.

Pathways for Intracranial Thrombosis

Pathways related to Intracranial Thrombosis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.89 APOH F3 F5 F8 FGA ITGA2B
2
Show member pathways
12.44 F3 F5 F8 FGA SERPINC1
3
Show member pathways
11.96 FGA ITGA2B VWF
4
Show member pathways
11.82 FGA ITGA2B VWF
5
Show member pathways
11.74 FGA ITGA2B VWF
6
Show member pathways
11.7 F3 F5 F8 FGA PLG SERPINC1
7 11.67 FGA ITGA2B VWF
8
Show member pathways
11.54 FGA ITGA2B VWF
9 11.31 F3 F5 F8 FGA PLG SERPINC1
10 11.14 FGA ITGA2B VWF

GO Terms for Intracranial Thrombosis

Cellular components related to Intracranial Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 extracellular exosome GO:0070062 9.93 APOH FGA ITGA2B PLG SERPINC1 VWF
2 extracellular space GO:0005615 9.92 APOH F3 F5 F8 FGA PLA2G7
3 extracellular region GO:0005576 9.81 APOH F3 F5 F8 FGA PLA2G7
4 cell surface GO:0009986 9.8 APOH F3 FGA ITGA2B PLG
5 endoplasmic reticulum lumen GO:0005788 9.73 F5 F8 FGA SERPINC1
6 blood microparticle GO:0072562 9.67 FGA ITGA2B PLG SERPINC1
7 COPII-coated ER to Golgi transport vesicle GO:0030134 9.48 F5 F8
8 platelet alpha granule GO:0031091 9.43 F5 FGA VWF
9 collagen-containing extracellular matrix GO:0062023 9.43 APOH F3 FGA PLG SERPINC1 VWF
10 platelet alpha granule lumen GO:0031093 9.02 F5 F8 FGA PLG VWF

Biological processes related to Intracranial Thrombosis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 blood coagulation GO:0007596 9.7 F3 F5 F8 FGA PLG SERPINC1
2 extracellular matrix organization GO:0030198 9.67 FGA ITGA2B VWF
3 cellular protein metabolic process GO:0044267 9.62 F5 FGA PLG SERPINC1
4 platelet activation GO:0030168 9.61 F8 FGA VWF
5 platelet aggregation GO:0070527 9.52 FGA ITGA2B
6 blood circulation GO:0008015 9.51 F5 MTHFR
7 platelet degranulation GO:0002576 9.5 APOH F5 F8 FGA ITGA2B PLG
8 fibrinolysis GO:0042730 9.48 FGA PLG
9 regulation of blood coagulation GO:0030193 9.46 APOH SERPINC1
10 blood coagulation, intrinsic pathway GO:0007597 9.43 APOH F8 VWF
11 plasminogen activation GO:0031639 9.4 APOH FGA
12 negative regulation of fibrinolysis GO:0051918 9.37 APOH PLG
13 hemostasis GO:0007599 9.17 F3 F5 F8 FGA PLG SERPINC1

Molecular functions related to Intracranial Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 phospholipid binding GO:0005543 9.13 APOH F3 PLA2G7
2 protease binding GO:0002020 8.8 F3 SERPINC1 VWF

Sources for Intracranial Thrombosis

3 CDC
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63 PubMed
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70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
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75 UMLS via Orphanet
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