MCID: INT078
MIFTS: 50

Intracranial Thrombosis

Categories: Blood diseases, Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Intracranial Thrombosis

MalaCards integrated aliases for Intracranial Thrombosis:

Name: Intracranial Thrombosis 12 44 15 70
Cerebral Thrombosis 12 73 54 6 70
Thrombosis of Cerebral Veins 70
Cerebral Arterial Thrombosis 70

Classifications:



External Ids:

Disease Ontology 12 DOID:4193
ICD9CM 34 434.0
MeSH 44 D020767
SNOMED-CT 67 155401002
UMLS 70 C0079102 C0151945 C0752143 more

Summaries for Intracranial Thrombosis

MalaCards based summary : Intracranial Thrombosis, also known as cerebral thrombosis, is related to polycythemia and homocystinuria. An important gene associated with Intracranial Thrombosis is SERPINC1 (Serpin Family C Member 1), and among its related pathways/superpathways are Collagen chain trimerization and Response to elevated platelet cytosolic Ca2+. The drugs Tenecteplase and Dalteparin have been mentioned in the context of this disorder. Affiliated tissues include endothelial, liver and whole blood, and related phenotypes are homeostasis/metabolism and cardiovascular system

Wikipedia : 73 A thrombus, colloquially called a blood clot, is the final product of the blood coagulation step in... more...

Related Diseases for Intracranial Thrombosis

Diseases related to Intracranial Thrombosis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 333)
# Related Disease Score Top Affiliating Genes
1 polycythemia 30.5 SERPINC1 F5 F2
2 homocystinuria 30.0 SERPINC1 MTHFR F8 F5
3 eclampsia 30.0 SERPINC1 MTHFR F2
4 heparin-induced thrombocytopenia 29.9 SERPINC1 F3 F10
5 polycythemia vera 29.9 VWF SELP F5 F2
6 mastoiditis 29.9 SERPINC1 MTHFR F2
7 hemophilia a 29.9 VWF F8 F5 F3
8 protein c deficiency 29.8 SERPINC1 MTHFR F5 F2 APOH
9 cerebral sinovenous thrombosis 29.8 MTHFR F5 F3 F2 APOH
10 papilledema 29.8 SERPINC1 F3 F2 APOH
11 nephrotic syndrome 29.8 SERPINC1 PLG FGA F3 F2
12 beta-thalassemia 29.7 SERPINC1 MTHFR F5 F2
13 paroxysmal nocturnal hemoglobinuria 29.7 SERPINC1 SELP F2
14 homocysteinemia 29.6 VWF SERPINC1 MTHFR F5 F2 APOH
15 atherosclerosis susceptibility 29.6 VWF SELP PLA2G7 MTHFR F3
16 placental abruption 29.6 SERPINC1 MTHFR F5 F2 APOH
17 middle cerebral artery infarction 29.5 PLG PLAT
18 acute cor pulmonale 29.5 PLG PLAT F3 F2
19 protein s deficiency 29.4 SERPINC1 MTHFR FGA F5 F3 F2
20 factor xiii deficiency 29.4 VWF SERPINC1 F8 F5 F3 F2
21 dysfibrinogenemia, congenital 29.3 SERPINC1 PLAT FGA F5 F2
22 ischemia 29.3 SELP PLG PLAT GP1BA
23 thrombocytosis 29.2 VWF SERPINC1 SELP FGA F3 F2
24 intracranial embolism 29.1 VWF SERPINC1 SELP PLG PLAT F3
25 endocarditis 29.1 SERPINC1 PLAT GP1BA F2 APOH
26 inflammatory bowel disease 29.1 SERPINC1 SELP MTHFR F5 F3 F2
27 sickle cell anemia 29.1 VWF MTHFR ITGA2B GP1BA F2
28 deficiency anemia 28.9 SERPINC1 SELP PLG GP1BA F5 F2
29 antithrombin iii deficiency 28.8 SERPINC1 PLG MTHFR FGA F5 F2
30 acute myocardial infarction 28.7 VWF SERPINC1 SELP PLG PLAT ITGA2B
31 thrombophlebitis 28.6 VWF SERPINC1 PLG PLAT MTHFR F8
32 antiphospholipid syndrome 28.5 VWF SERPINC1 SELP PLAT MTHFR F5
33 factor viii deficiency 28.5 VWF SERPINC1 F8 F5 F3 F2
34 essential thrombocythemia 28.4 VWF SERPINC1 SELP MTHFR ITGA2B GP1BA
35 disseminated intravascular coagulation 28.4 VWF SERPINC1 PLG PLAT FGA F5
36 heart disease 27.6 VWF SERPINC1 SELP PLAT MTHFR ITGA2B
37 cerebrovascular disease 27.6 VWF SELP PLAT MTHFR ITGA2B GP1BA
38 coronary thrombosis 27.5 VWF SERPINC1 SELP PLG PLAT ITGA2B
39 thrombophilia 27.4 VWF SERPINC1 SELP PLAT MTHFR FGA
40 pulmonary embolism 27.4 VWF SERPINC1 PLAT MTHFR GP6 GP1BA
41 carotid artery thrombosis 26.8 VWF SERPINC1 SELP PLG PLAT ITGA2B
42 vascular disease 26.2 VWF SERPINC1 SELP PLG PLAT PLA2G7
43 thrombosis 25.9 VWF SERPINC1 SELP PLG PLAT MTHFR
44 thrombocytopenia 25.5 VWF SERPINC1 SELP PLG PLAT MTHFR
45 myocardial infarction 25.4 VWF SERPINC1 SELP PLG PLAT PLA2G7
46 glycosylphosphatidylinositol biosynthesis defect 1 11.0
47 may-thurner syndrome 10.4 F5 APOH
48 acanthamoeba keratitis 10.4 F5 APOH
49 vulvar angiokeratoma 10.4 SERPINC1 F3
50 cerebral arteritis 10.4 SERPINC1 F8

Comorbidity relations with Intracranial Thrombosis via Phenotypic Disease Network (PDN): (show all 19)


Active Peptic Ulcer Disease Acute Cystitis
Aortic Valve Disease 1 Benign Essential Hypertension
Cerebral Atherosclerosis Cerebrovascular Disease
Decubitus Ulcer Epilepsy, Focal, with Speech Disorder and with or Without Mental Retardation
Familial Atrial Fibrillation Generalized Atherosclerosis
Heart Disease Hypertension, Essential
Intracranial Embolism Malignant Essential Hypertension
Peripheral Vascular Disease Schizophreniform Disorder
Spastic Hemiplegia Swallowing Disorders
Transient Cerebral Ischemia

Graphical network of the top 20 diseases related to Intracranial Thrombosis:



Diseases related to Intracranial Thrombosis

Symptoms & Phenotypes for Intracranial Thrombosis

MGI Mouse Phenotypes related to Intracranial Thrombosis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 10.33 APOH F10 F11 F2 F3 F5
2 cardiovascular system MP:0005385 10.26 F10 F11 F2 F3 F5 FGA
3 hematopoietic system MP:0005397 10.21 F11 F3 F8 FGA GP1BA GP6
4 cellular MP:0005384 10.2 F11 F2 F3 FGA GP1BA ITGA2B
5 immune system MP:0005387 10.18 F11 F2 F3 F8 FGA GP6
6 mortality/aging MP:0010768 10.09 APOH F10 F11 F2 F3 F5
7 integument MP:0010771 10.02 F2 F3 F5 FGA GP6 ITGA2B
8 liver/biliary system MP:0005370 9.8 F11 F5 FGA MTHFR PLG SELP
9 nervous system MP:0003631 9.73 F11 F2 F3 F5 FGA ITGA2B
10 reproductive system MP:0005389 9.32 F10 F2 F8 FGA GP6 ITGA2B

Drugs & Therapeutics for Intracranial Thrombosis

Drugs for Intracranial Thrombosis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 37)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Tenecteplase Approved Phase 3 191588-94-0
2
Dalteparin Approved Phase 2, Phase 3 9005-49-6
3
Heparin Approved, Investigational Phase 2, Phase 3 9005-49-6 772 9812414
4
Tinzaparin Approved Phase 2, Phase 3 9041-08-1, 9005-49-6 25244225
5 Plasminogen Phase 3
6 Plasminogen Inactivators Phase 3
7 Fibrinolytic Agents Phase 2, Phase 3
8 Tissue Plasminogen Activator Phase 2, Phase 3
9 Anticoagulants Phase 2, Phase 3
10 Heparin, Low-Molecular-Weight Phase 2, Phase 3
11 calcium heparin Phase 2, Phase 3
12
Ethinyl Estradiol Approved 57-63-6 5991
13
Ferrous fumarate Approved 141-01-5
14
Polyestradiol phosphate Approved 28014-46-2
15
Estradiol Approved, Investigational, Vet_approved 50-28-2 5757
16
Levonorgestrel Approved, Investigational 797-63-7, 17489-40-6 13109
17
Norethindrone Approved 68-22-4 6230
18
Angiotensin II Approved, Investigational 68521-88-0, 11128-99-7, 4474-91-3 172198
19
Thrombin Approved, Investigational
20 Ethinyl estradiol, levonorgestrel drug combination
21 Contraceptives, Oral, Hormonal
22 Contraceptive Agents
23 Estradiol 3-benzoate
24 Contraceptives, Oral
25 Hormone Antagonists
26 Contraceptives, Oral, Combined
27 Hormones
28 Estradiol 17 beta-cypionate
29 Norinyl
30 Estrogens
31 Norethindrone acetate, ethinyl estradiol, ferrous fumarate drug combination
32 Norethindrone Acetate
33 polysaccharide-K
34 Giapreza
35 Angiotensinogen
36 Plasminogen Activator Inhibitor 1
37 Liver Extracts

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Alteplase Compared to Tenecteplase in Patients With Acute Ischemic Stroke: QuICR & OPTIMISE Registry Based Pragmatic Randomized Controlled Trial Recruiting NCT03889249 Phase 3 Tenecteplase;Alteplase
2 Thrombolysis or Anticoagulation for Cerebral Venous Thrombosis (TOACT) Terminated NCT01204333 Phase 2, Phase 3 Endovascular thrombolysis;Heparin
3 Prevention for the Restenosis of Intracranial Artery Stent Implantation Treated With Herbal Medicine C117--PRISIT Trial Unknown status NCT03008798 Phase 2 Herbal Medicine C-117;The Placebo of Herbal Medicine C-117
4 Cyanotic Congenital Heart Disease: Prevalence of Pulmonary and Cerebral Thrombi-embolic Events Completed NCT02716402
5 Utility of Modern Ultrasound Techniques in the Evaluation of Cerebral Venous Sinuses in Neonates Completed NCT00555932
6 The Impact of Cranioplasty on Local and Global Cerebral Blood Flow as Clinical Outcome Prognostic Factor in Patients Undergoing Decompressive Craniectomy for Severe Head Injury. Completed NCT01113645
7 Postmarketing Study Of Lybrel In Relation To Venous Thromboembolism Completed NCT01297348 90ug levonorgestrel / 20 ug ethinyl estradiol;Oral Contraceptives containing 20 ug of ethinyl estradiol
8 adaptatiVe Endovascular Strategy to the CloT MRI in Large Intracranial Vessel Occlusion Recruiting NCT04139486
9 The Safety and Efficacy of Intracranial Thrombosis Aspiration Catheter for Recanalization in Acute Ischemic Stroke Therapy- A Prospective, Multicenter, Open Label, Blinded, Randomized Controlled, Non-inferiority Study Recruiting NCT03753061
10 Investigating the Involvement of ACE and Angiotensinogen Genes' Polymorphism Along With Other Thrombophilic Genotypes in Severe Forms of COVID-19 With/Without Thrombotic Events Recruiting NCT04519398

Search NIH Clinical Center for Intracranial Thrombosis

Cochrane evidence based reviews: intracranial thrombosis

Genetic Tests for Intracranial Thrombosis

Anatomical Context for Intracranial Thrombosis

MalaCards organs/tissues related to Intracranial Thrombosis:

40
Endothelial, Liver, Whole Blood, Brain, Thymus, Retina, Thyroid

Publications for Intracranial Thrombosis

Articles related to Intracranial Thrombosis:

(show top 50) (show all 698)
# Title Authors PMID Year
1
Cerebral thrombosis associated with heterozygous factor V Leiden mutation and high lipoprotein(a) level in a girl with factor XIII deficiency. 54 61
17473580 2007
2
Significance of factor V, prothrombin, MTHFR, and PAI-1 genotypes in childhood cerebral thrombosis. 61 54
17456624 2007
3
[A 50-year history of new drugs in Japan-the development and trends of hemostatics and antithrombotic drugs]. 61 54
14570069 2003
4
Development of argatroban as an anticoagulant and antithrombin agent in Japan. 54 61
12811008 2002
5
[Neonatal cerebral thrombosis and deficit of factor V leiden]. 54 61
11003860 2000
6
Sustained activation of blood coagulation in patients with cerebral thrombosis. 54 61
7485075 1995
7
A case of cerebral infarction associated with positive antiphospholipid antibody in a systemic lupus patient. 61 54
8038146 1994
8
[Coagulation and fibrinolytic parameters in patients with various angiopathies--analysis in cerebral thrombosis, diabetic and vasculitic neuropathies]. 54 61
8403679 1993
9
Platelet-activating factor acetylhydrolase in plasma lipoproteins from patients with ischemic stroke. 61 54
1636183 1992
10
Platelet-activating factor acetylhydrolase activity in red blood cell-stroma from patients with cerebral thrombosis. 54 61
1414232 1992
11
Coagulation-fibrinolysis abnormalities in acute and chronic phases of cerebral thrombosis and embolism. 54 61
2148232 1990
12
Autoantibodies to Annexin A2 and cerebral thrombosis: Insights from a mouse model. 61
33554716 2021
13
Ultra-Early Cerebral Thrombosis Formation After Experimental Subarachnoid Hemorrhage Detected on T2* Magnetic Resonance Imaging. 61
33535782 2021
14
Effects of breviscapine and C3435T MDR1 gene polymorphism on the pharmacokinetics of fexofenadine, a P-glycoprotein substrate, in healthy volunteers. 61
33256506 2021
15
Stroke in COVID-19: A systematic review and meta-analysis. 61
33103610 2021
16
Epidural blood patch for the treatment of liquor hypotension after intrathecal chemotherapy in a 10-year-old: case report. 61
33714610 2021
17
Computed tomography perfusion in patients of stroke with left ventricular assist device. 61
32776236 2021
18
Effect of Zanthoxylum alkylamides on lipid metabolism and its mechanism in rats fed with a high-fat diet. 61
33270233 2021
19
Delayed cerebral thrombosis complicating bacterial meningitis. 61
33455561 2021
20
Characterization of chemical components in the Guanxinning injection by liquid chromatography-mass spectrometry. 61
33166042 2020
21
Coronary and cerebral thrombosis in a young patient after mild COVID-19 illness: a case report. 61
33200109 2020
22
[An hereditary hemorrhagic telangiectasia of late revealed by a cerebral venous thrombosis: A case report]. 61
32565074 2020
23
Association Between Residential Greenness, Cardiometabolic Disorders, and Cardiovascular Disease Among Adults in China. 61
32955574 2020
24
Cerebral Venous Thrombosis Associated with COVID-19. 61
32554424 2020
25
Venous cerebral thrombosis in COVID-19 patient. 61
32422428 2020
26
Targeting Myeloid-Specific Integrin α9β1 Improves Short- and Long-Term Stroke Outcomes in Murine Models With Preexisting Comorbidities by Limiting Thrombosis and Inflammation. 61
32195632 2020
27
Relationship between Flow-mediated Endothelial Vasodilation and the Pulse Wave Velocity, and Cervical Carotid Artery Stenosis. 61
32404574 2020
28
Posterior reversible encephalopathy syndrome in an oncological normotensive patient: evidence for a pathogenic role of concomitant low magnesium serum levels and chemotherapy treatment. 61
32420975 2020
29
Repurposing antimycotic ciclopirox olamine as a promising anti-ischemic stroke agent. 61
32140390 2020
30
Analysis of 10 Pediatric Nephrotic Syndrome Cases With Complications of Cerebral Sinovenous Thrombosis. 61
33425818 2020
31
Effects of Astragalus Polysaccharides Nanoparticles on Cerebral Thrombosis in SD Rats. 61
33425879 2020
32
SS-SWT and SI-CNN: An Atrial Fibrillation Detection Framework for Time-Frequency ECG Signal. 61
32509259 2020
33
Protein-Carbon Dot Nanohybrid-Based Early Blood-Brain Barrier Damage Theranostics. 61
31922399 2020
34
The Joint Effect of a Combination of Components From the Fruit of Crataegus pinnatifida Bge. Var. major N.E. Br. and the Root of Salvia miltiorrhiza Bge. With Exercises on Swimming in Focal Cerebral Infraction in Rat. 61
33329023 2020
35
Scutellarin inhibits hypoxia-induced epithelial-mesenchymal transition in bladder cancer cells. 61
31127618 2019
36
[Efficacy and safety of Shenxiong Glucose Injection in treatment of cerebral thrombosis:systematic review and Meta-analysis]. 61
31602832 2019
37
Novel Role for the AnxA1-Fpr2/ALX Signaling Axis as a Key Regulator of Platelet Function to Promote Resolution of Inflammation. 61
31154815 2019
38
[Study on mechanism of Xixian Tongshuan Capsules based on network pharmacology]. 61
31342720 2019
39
Early diagnosis of cerebral thrombosis by EGFP-EGF1 protein conjugated ferroferric oxide magnetic nanoparticles. 61
30646803 2019
40
Antibiotic and Anticoagulation Therapy in Lemierre's Syndrome: Case Report and Review. 61
30773133 2019
41
Drug-Loaded Microbubbles Combined with Ultrasound for Thrombolysis and Malignant Tumor Therapy. 61
31662987 2019
42
Multicenter randomized trial of arsenic trioxide and Realgar-Indigo naturalis formula in pediatric patients with acute promyelocytic leukemia: Interim results of the SCCLG-APL clinical study. 61
30160789 2018
43
Association between urinary sodium excretion and coronary heart disease in hospitalized elderly patients in China. 61
29756493 2018
44
Stem Cell Factor in Combination with Granulocyte Colony-Stimulating Factor reduces Cerebral Capillary Thrombosis in a Mouse Model of CADASIL. 61
29871518 2018
45
Recent progress in the structural modification and pharmacological activities of ligustrazine derivatives. 61
29432947 2018
46
Heterozygous FGA p.Asp473Ter (fibrinogen Nieuwegein) presenting as antepartum cerebral thrombosis. 61
29122299 2018
47
Delayed cerebral thrombosis complicating pneumococcal meningitis: an autopsy study. 61
29427117 2018
48
Coexistent Ipsilateral Internal Carotid Artery Occlusion and Cerebral Venous Thrombosis in Hepatitis C. 61
29349091 2018
49
GPVI‑Fc‑PEG improves cerebral infarct volume and cerebral thrombosis in mouse model with cerebral thrombosis. 61
28944903 2017
50
Spinal epidural haematoma following thrombolysis for acute ischaemic stroke in patient within 48h of emergency lumbar microdiscectomy. 61
27549024 2017

Variations for Intracranial Thrombosis

ClinVar genetic disease variations for Intracranial Thrombosis:

6
# Gene Name Type Significance ClinVarId dbSNP ID Position
1 CACNA1A NM_001127222.2(CACNA1A):c.6125C>T (p.Thr2042Met) SNV Uncertain significance 386521 rs563345694 GRCh37: 19:13323262-13323262
GRCh38: 19:13212448-13212448
2 COL6A2 NM_001849.3(COL6A2):c.2008A>G (p.Thr670Ala) SNV Uncertain significance 598977 rs753298014 GRCh37: 21:47545737-47545737
GRCh38: 21:46125823-46125823

Expression for Intracranial Thrombosis

Search GEO for disease gene expression data for Intracranial Thrombosis.

Pathways for Intracranial Thrombosis

Pathways related to Intracranial Thrombosis according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.7 SERPINC1 FGA F8 F5 F3 F2
2
Show member pathways
12.6 VWF SERPINC1 SELP PLG PLAT ITGA2B
3
Show member pathways
12.14 PLG PLAT MTHFR F2
4 12.06 VWF SERPINC1 PLG PLAT FGA F8
5
Show member pathways
12.05 VWF ITGA2B GP6 GP1BA FGA
6
Show member pathways
11.97 VWF SERPINC1 PLG PLAT GP6 GP1BA
7 11.83 VWF ITGA2B GP6 GP1BA FGA F2
8
Show member pathways
11.79 VWF ITGA2B GP1BA FGA F2
9 11.43 VWF ITGA2B GP6 FGA F2
10 11.42 SELP PLG PLAT GP1BA
11 11.36 PLG PLAT FGA
12 10.77 VWF GP6 GP1BA
13 10.72 F2 F10
14 10.65 PLG PLAT
15 10.52 VWF GP1BA

GO Terms for Intracranial Thrombosis

Cellular components related to Intracranial Thrombosis according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 plasma membrane GO:0005886 10.31 SERPINC1 SELP PLG ITGA2B GP6 GP1BA
2 extracellular exosome GO:0070062 10.11 VWF SERPINC1 PLG PLAT ITGA2B GP6
3 extracellular region GO:0005576 9.97 VWF SERPINC1 PLG PLAT PLA2G7 FGA
4 cell surface GO:0009986 9.92 PLG PLAT ITGA2B GP6 GP1BA FGA
5 endoplasmic reticulum lumen GO:0005788 9.88 SERPINC1 FGA F8 F5 F2 F10
6 blood microparticle GO:0072562 9.83 SERPINC1 PLG ITGA2B FGA F2
7 platelet alpha granule lumen GO:0031093 9.65 VWF PLG FGA F8 F5
8 platelet alpha granule GO:0031091 9.63 VWF FGA F5
9 collagen-containing extracellular matrix GO:0062023 9.56 VWF SERPINC1 PLG PLAT FGA F3
10 platelet alpha granule membrane GO:0031092 9.51 SELP ITGA2B
11 extracellular space GO:0005615 9.5 VWF SERPINC1 SELP PLG PLAT PLA2G7
12 intrinsic component of external side of plasma membrane GO:0031233 9.48 F3 F10

Biological processes related to Intracranial Thrombosis according to GeneCards Suite gene sharing:

(show all 17)
# Name GO ID Score Top Affiliating Genes
1 proteolysis GO:0006508 9.97 PLG PLAT F2 F11 F10
2 cellular protein metabolic process GO:0044267 9.88 SERPINC1 PLG FGA F5 F2
3 platelet activation GO:0030168 9.88 VWF GP6 GP1BA FGA F8 F2
4 platelet degranulation GO:0002576 9.86 VWF SELP PLG ITGA2B FGA F8
5 ER to Golgi vesicle-mediated transport GO:0006888 9.84 F8 F5 F2 F10
6 fibrinolysis GO:0042730 9.77 PLG PLAT GP1BA FGA F2
7 plasminogen activation GO:0031639 9.73 PLAT FGA F11 APOH
8 hemostasis GO:0007599 9.73 VWF SERPINC1 PLG GP6 GP1BA FGA
9 regulation of blood coagulation GO:0030193 9.72 SERPINC1 GP1BA F2 F11 APOH
10 platelet aggregation GO:0070527 9.7 ITGA2B GP1BA FGA
11 negative regulation of fibrinolysis GO:0051918 9.63 PLG F2 APOH
12 blood coagulation, intrinsic pathway GO:0007597 9.63 VWF GP1BA F8 F2 F11 APOH
13 positive regulation of blood coagulation GO:0030194 9.56 F2 APOH
14 positive regulation of leukocyte migration GO:0002687 9.55 SELP ITGA2B
15 positive regulation of fibrinolysis GO:0051919 9.51 PLG F11
16 blood coagulation, extrinsic pathway GO:0007598 9.49 F3 F10
17 blood coagulation GO:0007596 9.44 VWF SERPINC1 PLG PLAT GP6 GP1BA

Molecular functions related to Intracranial Thrombosis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptidase activity GO:0008233 9.72 PLG PLAT F2 F11 F10
2 phospholipid binding GO:0005543 9.56 PLA2G7 F3 F10 APOH
3 heparin binding GO:0008201 9.55 SERPINC1 SELP F2 F11 APOH
4 protease binding GO:0002020 9.54 VWF SERPINC1 F3
5 serine-type peptidase activity GO:0008236 9.35 PLG PLAT F2 F11 F10
6 serine-type endopeptidase activity GO:0004252 9.1 PLG PLAT F3 F2 F11 F10

Sources for Intracranial Thrombosis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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