MCID: INT053
MIFTS: 28

Intracranial Vasospasm

Categories: Cardiovascular diseases, Neuronal diseases

Aliases & Classifications for Intracranial Vasospasm

MalaCards integrated aliases for Intracranial Vasospasm:

Name: Intracranial Vasospasm 12 15
Vasospasm, Intracranial 44 73

Classifications:



External Ids:

Disease Ontology 12 DOID:13100
MeSH 44 D020301
UMLS 73 C0751895

Summaries for Intracranial Vasospasm

MalaCards based summary : Intracranial Vasospasm, also known as vasospasm, intracranial, is related to stroke, ischemic and geniculate herpes zoster. An important gene associated with Intracranial Vasospasm is HP (Haptoglobin), and among its related pathways/superpathways are Fluid shear stress and atherosclerosis and Apelin signaling pathway. Affiliated tissues include heart, and related phenotypes are hematopoietic system and immune system

Related Diseases for Intracranial Vasospasm

Graphical network of the top 20 diseases related to Intracranial Vasospasm:



Diseases related to Intracranial Vasospasm

Symptoms & Phenotypes for Intracranial Vasospasm

MGI Mouse Phenotypes related to Intracranial Vasospasm:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 hematopoietic system MP:0005397 9.35 APOE HP NOS3 PLAT TSPAN33
2 immune system MP:0005387 9.02 APOE HP NOS3 PLAT TSPAN33

Drugs & Therapeutics for Intracranial Vasospasm

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The Tilburg Vasospasm Study Terminated NCT01407614 Phase 2, Phase 3

Search NIH Clinical Center for Intracranial Vasospasm

Cochrane evidence based reviews: vasospasm, intracranial

Genetic Tests for Intracranial Vasospasm

Anatomical Context for Intracranial Vasospasm

MalaCards organs/tissues related to Intracranial Vasospasm:

41
Heart

Publications for Intracranial Vasospasm

Articles related to Intracranial Vasospasm:

(show all 13)
# Title Authors Year
1
Intracranial Vasospasm without Intracranial Hemorrhage due to Acute Spontaneous Spinal Subdural Hematoma. ( 26713084 )
2015
2
Treatment of intracranial vasospasm following subarachnoid hemorrhage. ( 24904517 )
2014
3
Intracranial vasospasm with delayed ischaemic deficit following epidermoid cyst resection. ( 20603397 )
2010
4
Intracranial vasospasm with subsequent stroke after traumatic subarachnoid hemorrhage in a 22-month-old child. ( 19338410 )
2009
5
Anesthetic considerations of selective intra-arterial nicardipine injection for intracranial vasospasm: a case series. ( 17413999 )
2007
6
Delayed intracranial vasospasm following carotid endarterectomy. ( 16088117 )
2005
7
Three-dimensional CT angiography of intracranial vasospasm following subarachnoid haemorrhage. ( 9833891 )
1998
8
Severe diffuse intracranial vasospasm as a cause of extensive migrainous cerebral infarction. ( 8374945 )
1993
9
Role of transcranial Doppler in neuroradiological treatment of intracranial vasospasm. ( 8421832 )
1993
10
Intraarterial papaverine for relief of catheter-induced intracranial vasospasm. ( 1546611 )
1992
11
Bilateral cervical carotid and intracranial vasospasm causing cerebral ischemia in a migrainous patient: a case of "diplegic migraine". ( 6490360 )
1984
12
Intracranial vasospasm: a study with iron compounds. ( 35848 )
1979
13
The relief of intracranial vasospasm: an experimental study with methylprednisolone and cortisol. ( 806982 )
1975

Variations for Intracranial Vasospasm

Expression for Intracranial Vasospasm

Search GEO for disease gene expression data for Intracranial Vasospasm.

Pathways for Intracranial Vasospasm

Pathways related to Intracranial Vasospasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.4 NOS3 PLAT
2 11.29 NOS3 PLAT
3
Show member pathways
10.97 APOE HP
4 10.3 HP PLAT

GO Terms for Intracranial Vasospasm

Cellular components related to Intracranial Vasospasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 blood microparticle GO:0072562 8.96 APOE HP
2 endocytic vesicle lumen GO:0071682 8.62 APOE HP

Biological processes related to Intracranial Vasospasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cellular oxidant detoxification GO:0098869 9.26 APOE HP
2 vasodilation GO:0042311 9.16 APOE NOS3
3 nitric oxide mediated signal transduction GO:0007263 8.96 APOE NOS3
4 negative regulation of platelet activation GO:0010544 8.62 APOE NOS3

Molecular functions related to Intracranial Vasospasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 antioxidant activity GO:0016209 8.62 APOE HP

Sources for Intracranial Vasospasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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