MCID: INT015
MIFTS: 29

Intracystic Papillary Adenoma

Categories: Cancer diseases

Aliases & Classifications for Intracystic Papillary Adenoma

MalaCards integrated aliases for Intracystic Papillary Adenoma:

Name: Intracystic Papillary Adenoma 12 15 71
Intracystic Papilloma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2682
NCIt 49 C4191
SNOMED-CT 67 47488001
UMLS 71 C0334374

Summaries for Intracystic Papillary Adenoma

MalaCards based summary : Intracystic Papillary Adenoma, also known as intracystic papilloma, is related to gynecomastia and papillary carcinoma, and has symptoms including nipple discharge An important gene associated with Intracystic Papillary Adenoma is CCDC59 (Coiled-Coil Domain Containing 59), and among its related pathways/superpathways are Gastric cancer and Glucocorticoid receptor regulatory network. Affiliated tissues include breast, ovary and colon, and related phenotypes are cellular and endocrine/exocrine gland

Related Diseases for Intracystic Papillary Adenoma

Diseases related to Intracystic Papillary Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 248)
# Related Disease Score Top Affiliating Genes
1 gynecomastia 30.2 PRL PGR ESR1 ERBB2
2 papillary carcinoma 29.6 PGR ESR1 ERBB2 CHGA
3 intraductal papilloma 29.4 PGR KRT5 KRT14 ESR1 ERBB2
4 squamous cell papilloma 10.6
5 papilloma 10.6
6 sebaceous breast carcinoma 10.5 ERBB2 CEACAM5
7 eccrine mixed tumor of skin 10.5 ERBB2 CEACAM5
8 parotid gland adenoid cystic carcinoma 10.5 ERBB2 CEACAM5
9 malignant spiradenoma 10.5 KRT5 CEACAM5
10 ureter adenocarcinoma 10.5 KRT5 CEACAM5
11 mucoepidermoid esophageal carcinoma 10.5 KRT5 CEACAM5
12 malignant acrospiroma 10.5 KRT5 CEACAM5
13 gallbladder squamous cell carcinoma 10.5 KRT5 CEACAM5
14 vulval paget's disease 10.5 ERBB2 CEACAM5
15 eccrine porocarcinoma 10.5 KRT5 CEACAM5
16 thymus adenocarcinoma 10.5 KRT5 CEACAM5
17 malignant epithelial mesothelioma 10.5 KRT5 CEACAM5
18 vulva adenocarcinoma 10.5 ERBB2 CEACAM5
19 scirrhous adenocarcinoma 10.5 PGR ERBB2
20 pancreatic cystadenocarcinoma 10.5 CPQ CEACAM5
21 vulvar apocrine adenocarcinoma 10.5 KRT5 CEACAM5
22 vagina leiomyoma 10.5 PGR CEACAM5
23 pancreatic serous cystadenoma 10.5 CPQ CEACAM5
24 lactocele 10.5 PRL PPP3R1
25 cervical serous adenocarcinoma 10.5 PGR CEACAM5
26 apocrine adenosis of breast 10.4 PGR ERBB2
27 bile duct mucoepidermoid carcinoma 10.4 KRT5 CEACAM5
28 clear cell hidradenoma 10.4 KRT5 CEACAM5
29 pyometritis 10.4 PRL PGR
30 breast adenoid cystic carcinoma 10.4 PGR ERBB2
31 eccrine sweat gland cancer 10.4 KRT5 CEACAM5
32 benign mesothelioma 10.4 KRT5 CEACAM5
33 pericardium cancer 10.4 KRT5 CEACAM5
34 colonic lymphangioma 10.4 CEACAM5 ACR
35 urethral benign neoplasm 10.4 KRT5 CEACAM5
36 eccrine acrospiroma 10.4 KRT5 CEACAM5
37 breast duct papilloma 10.4
38 breast cystic hypersecretory carcinoma 10.4 KRT5 ERBB2 CEACAM5
39 vulva basal cell carcinoma 10.4 KRT5 ERBB2 CEACAM5
40 esophageal adenosquamous carcinoma 10.4 KRT5 ERBB2 CEACAM5
41 paget disease, extramammary 10.4 KRT5 ERBB2 CEACAM5
42 nasal cavity olfactory neuroblastoma 10.3 KRT5 CEACAM5
43 breast mucinous carcinoma 10.3 PGR KRT5 ERBB2
44 cystadenocarcinoma 10.3 PGR ERBB2 CEACAM5
45 pancreatic mucinous cystadenoma 10.3 PGR CEACAM5
46 linitis plastica 10.3 PGR ERBB2 CEACAM5
47 external ear carcinoma 10.3 PGR KRT5 CEACAM5
48 eccrine papillary adenocarcinoma 10.3 PGR KRT5 CEACAM5
49 gastric diffuse adenocarcinoma 10.3 PGR ERBB2 CEACAM5
50 adenosquamous carcinoma 10.3 PGR KRT5 CEACAM5

Graphical network of the top 20 diseases related to Intracystic Papillary Adenoma:



Diseases related to Intracystic Papillary Adenoma

Symptoms & Phenotypes for Intracystic Papillary Adenoma

UMLS symptoms related to Intracystic Papillary Adenoma:


nipple discharge

MGI Mouse Phenotypes related to Intracystic Papillary Adenoma:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 10.11 ACR BACE1 BRCA1 BRCA2 CCDC59 ERBB2
2 endocrine/exocrine gland MP:0005379 9.97 BRCA1 BRCA2 CHGA ERBB2 ESR1 KRT14
3 integument MP:0010771 9.91 BACE1 BRCA1 BRCA2 ERBB2 ESR1 KRT14
4 neoplasm MP:0002006 9.7 BRCA1 BRCA2 ERBB2 ESR1 KRT14 PGR
5 normal MP:0002873 9.61 ACR BACE1 BRCA1 BRCA2 ERBB2 ESR1
6 reproductive system MP:0005389 9.28 ACR BRCA1 BRCA2 CHGA ERBB2 ESR1

Drugs & Therapeutics for Intracystic Papillary Adenoma

Search Clinical Trials , NIH Clinical Center for Intracystic Papillary Adenoma

Genetic Tests for Intracystic Papillary Adenoma

Anatomical Context for Intracystic Papillary Adenoma

MalaCards organs/tissues related to Intracystic Papillary Adenoma:

40
Breast, Ovary, Colon, Lung, Pituitary, Thyroid, Kidney

Publications for Intracystic Papillary Adenoma

Articles related to Intracystic Papillary Adenoma:

(show all 31)
# Title Authors PMID Year
1
A case of quadruple primary malignancies including breast, tongue, and thyroid cancers and osteosarcoma in a young female without karyotype abnormality. 61
21562838 2014
2
Usefulness of contrast-enhanced ultrasonography for intracystic breast tumors: a report of three cases. 61
27277917 2014
3
Intracystic papilloma of the breast. 61
22764674 2012
4
Intracystic papillary carcinoma of breast harbors significant genomic alteration compared with intracystic papilloma: genome-wide copy number and LOH analysis using high-density single-nucleotide polymorphism microarrays. 61
21651641 2011
5
Intracystic papilloma of the breast forming a giant cyst. 61
19152017 2010
6
Benign intracystic papilloma of the male breast. 61
18716152 2008
7
Complex cystic breast masses: diagnostic approach and imaging-pathologic correlation. 61
18180235 2007
8
Atlas of breast magnetic resonance imaging. 61
17331837 2007
9
Percutaneous endoscopy-guided biopsy of an intracystic tumor with a mammary ductoscopy. 61
17485908 2007
10
Intracystic papilloma in the breast of a male given long-term phenothiazine therapy: a case report. 61
16518066 2006
11
Benign intracystic papilloma in the male breast. 61
16174163 2005
12
[Congenial seminal vesicle cyst with an intracystic papillary adenoma associated with ipsilateral renal agenesis]. 61
12402112 2002
13
Percutaneous endoscopy of an intracystic papilloma of the breast. 61
12199763 2002
14
Detection of chromosomal aneusomy by fluorescence in situ hybridization in fine-needle aspirates from breast tumors: application to the preoperative diagnosis of breast carcinoma. 61
11156521 2000
15
[Detection of numerical aberrations in chromosomes by fluorescence in situ hybridization in fine needle aspirates in the preoperative diagnosis of cancer]. 61
10635294 1999
16
Enhancement of the Nipple-Areolar-Complex on Contrast-Enhanced MR Imaging of the Breast. 61
11091660 1998
17
[Intracystic papilloma of the male breast associated with monolateral gynecomastia. Clinicopathological findings in a case]. 61
9638174 1998
18
Cholesterol granuloma of the breast presenting as an intracystic papilloma. 61
9536911 1997
19
Simultaneous Assay of ErbB-2 Protein and Carcinoembryonic Antigen in Cyst Fluid as an Aid in Diagnosing Cystic Lesions of the Breast. 61
11091503 1994
20
Papillary neoplasms of the breast: fine-needle aspiration findings in cystic and solid cases. 61
7924806 1994
21
Intracystic papilloma in male breast: ultrasonography and pneumocystography diagnosis. 61
8478444 1993
22
[Intracystic papilloma of the breast. 3 case reports]. 61
2236700 1990
23
The value of routine cytologic examination of breast cyst fluids. 61
3109184 1987
24
Squamous metaplasia of the breast. An ultrastructural and immunologic evaluation. 61
3898814 1985
25
[Intraductal (intracystic) papilloma of the male breast]. 61
6528760 1984
26
Breast masses in young girls. Report of five cases. 61
7134066 1982
27
The ultrastructure of apocrine cells in intracystic papilloma and fibrocystic disease of the breast. 61
4191043 1970
28
[Intracystic papilloma of the kidney with hemorrhage during correct anticoagulant therapy]. 61
13068805 1953
29
PSEUDOGLANDULAR type of intracystic papilloma. 61
14804064 1951
30
Intracystic papilloma of the breast. 61
19970494 1940
31
Case of Intracystic Papilloma of an Accessory Thyroid. 61
30437499 1908

Variations for Intracystic Papillary Adenoma

Expression for Intracystic Papillary Adenoma

Search GEO for disease gene expression data for Intracystic Papillary Adenoma.

Pathways for Intracystic Papillary Adenoma

Pathways related to Intracystic Papillary Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.02 PGR ESR1 ERBB2 BRCA2 BRCA1
2 11.25 PRL KRT5 KRT14
3
Show member pathways
10.96 PRL PGR ESR1 ERBB2

GO Terms for Intracystic Papillary Adenoma

Cellular components related to Intracystic Papillary Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 lateral element GO:0000800 8.62 BRCA2 BRCA1

Biological processes related to Intracystic Papillary Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator GO:0006978 9.16 BRCA2 BRCA1
2 hemidesmosome assembly GO:0031581 8.96 KRT5 KRT14
3 chordate embryonic development GO:0043009 8.62 BRCA2 BRCA1

Sources for Intracystic Papillary Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....