MCID: INT015
MIFTS: 23

Intracystic Papillary Adenoma

Categories: Cancer diseases

Aliases & Classifications for Intracystic Papillary Adenoma

MalaCards integrated aliases for Intracystic Papillary Adenoma:

Name: Intracystic Papillary Adenoma 12 15 72
Intracystic Papilloma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2682
NCIt 50 C4191
SNOMED-CT 68 47488001
UMLS 72 C0334374

Summaries for Intracystic Papillary Adenoma

MalaCards based summary : Intracystic Papillary Adenoma, also known as intracystic papilloma, is related to gynecomastia and papillary carcinoma, and has symptoms including nipple discharge An important gene associated with Intracystic Papillary Adenoma is ERBB2 (Erb-B2 Receptor Tyrosine Kinase 2), and among its related pathways/superpathways is Signaling by ERBB4. Affiliated tissues include breast, thyroid and kidney, and related phenotype is neoplasm.

Related Diseases for Intracystic Papillary Adenoma

Diseases related to Intracystic Papillary Adenoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 93)
# Related Disease Score Top Affiliating Genes
1 gynecomastia 29.9 PRL PGR
2 papillary carcinoma 29.8 PGR ERBB2
3 breast cancer 28.3 PRL PGR ERBB2 CEACAM5
4 squamous cell papilloma 10.6
5 papilloma 10.6
6 breast duct papilloma 10.4
7 gallbladder squamous cell carcinoma 10.2 ERBB2 CEACAM5
8 mucoepidermoid carcinoma 10.2 ERBB2 CEACAM5
9 vulval paget's disease 10.2 ERBB2 CEACAM5
10 vulva adenocarcinoma 10.2 ERBB2 CEACAM5
11 infant gynecomastia 10.2
12 ovary adenocarcinoma 10.1 ERBB2 CEACAM5
13 esophageal disease 10.1 ERBB2 CEACAM5
14 ovarian cancer 1 10.1 ERBB2 CEACAM5
15 renal hypodysplasia/aplasia 1 10.1
16 papillary adenoma 10.1
17 adenoma 10.1
18 granulosa cell tumor of the ovary 10.1 PRL ERBB2
19 intraductal papilloma 10.0
20 acromegaly 10.0
21 stomach disease 10.0 ERBB2 CEACAM5
22 cell type benign neoplasm 10.0 PRL CEACAM5
23 respiratory system cancer 9.9 ERBB2 CEACAM5
24 breast apocrine carcinoma 9.9 PGR ERBB2
25 scirrhous adenocarcinoma 9.9 PGR ERBB2
26 granulomatous endometritis 9.9 PGR CEACAM5
27 glassy cell carcinoma of the cervix 9.9 PGR ERBB2
28 breast metaplastic carcinoma 9.9 PGR ERBB2
29 breast mucoepidermoid carcinoma 9.9 PGR CEACAM5
30 breast scirrhous carcinoma 9.9 PGR ERBB2
31 breast medullary carcinoma 9.9 PGR ERBB2
32 progesterone-receptor negative breast cancer 9.9 PGR ERBB2
33 progesterone-receptor positive breast cancer 9.9 PGR ERBB2
34 apocrine adenocarcinoma 9.9 PGR ERBB2
35 adenoid basal cell carcinoma 9.9 PGR CEACAM5
36 pancreatic serous cystadenoma 9.9 PGR CEACAM5
37 breast adenoid cystic carcinoma 9.9 PGR ERBB2
38 uterine body mixed cancer 9.9 PGR ERBB2
39 gastric signet ring cell adenocarcinoma 9.9 PGR CEACAM5
40 microglandular adenosis 9.9 PGR ERBB2
41 inflammatory breast carcinoma 9.9 PGR ERBB2
42 luminal breast carcinoma 9.9 PGR ERBB2
43 uterine corpus cancer 9.9 PGR ERBB2
44 thoracic benign neoplasm 9.9 PGR ERBB2
45 breast benign neoplasm 9.9 PGR ERBB2
46 breast secretory carcinoma 9.9 PGR ERBB2
47 gonadal disease 9.9 PRL ERBB2
48 lipid-rich carcinoma 9.9 PGR ERBB2
49 pancreatic mucinous cystadenoma 9.9 PGR CEACAM5
50 congenital epulis 9.9 PGR CEACAM5

Graphical network of the top 20 diseases related to Intracystic Papillary Adenoma:



Diseases related to Intracystic Papillary Adenoma

Symptoms & Phenotypes for Intracystic Papillary Adenoma

UMLS symptoms related to Intracystic Papillary Adenoma:


nipple discharge

MGI Mouse Phenotypes related to Intracystic Papillary Adenoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 8.8 ERBB2 PGR PRL

Drugs & Therapeutics for Intracystic Papillary Adenoma

Search Clinical Trials , NIH Clinical Center for Intracystic Papillary Adenoma

Genetic Tests for Intracystic Papillary Adenoma

Anatomical Context for Intracystic Papillary Adenoma

MalaCards organs/tissues related to Intracystic Papillary Adenoma:

41
Breast, Thyroid, Kidney, Tongue

Publications for Intracystic Papillary Adenoma

Articles related to Intracystic Papillary Adenoma:

(show all 31)
# Title Authors PMID Year
1
A case of quadruple primary malignancies including breast, tongue, and thyroid cancers and osteosarcoma in a young female without karyotype abnormality. 38
21562838 2014
2
Usefulness of contrast-enhanced ultrasonography for intracystic breast tumors: a report of three cases. 38
27277917 2014
3
Intracystic papilloma of the breast. 38
22764674 2012
4
Intracystic papillary carcinoma of breast harbors significant genomic alteration compared with intracystic papilloma: genome-wide copy number and LOH analysis using high-density single-nucleotide polymorphism microarrays. 38
21651641 2011
5
Intracystic papilloma of the breast forming a giant cyst. 38
19152017 2010
6
Benign intracystic papilloma of the male breast. 38
18716152 2008
7
Complex cystic breast masses: diagnostic approach and imaging-pathologic correlation. 38
18180235 2007
8
Atlas of breast magnetic resonance imaging. 38
17331837 2007
9
Percutaneous endoscopy-guided biopsy of an intracystic tumor with a mammary ductoscopy. 38
17485908 2007
10
Intracystic papilloma in the breast of a male given long-term phenothiazine therapy: a case report. 38
16518066 2006
11
Benign intracystic papilloma in the male breast. 38
16174163 2005
12
[Congenial seminal vesicle cyst with an intracystic papillary adenoma associated with ipsilateral renal agenesis]. 38
12402112 2002
13
Percutaneous endoscopy of an intracystic papilloma of the breast. 38
12199763 2002
14
Detection of chromosomal aneusomy by fluorescence in situ hybridization in fine-needle aspirates from breast tumors: application to the preoperative diagnosis of breast carcinoma. 38
11156521 2000
15
[Detection of numerical aberrations in chromosomes by fluorescence in situ hybridization in fine needle aspirates in the preoperative diagnosis of cancer]. 38
10635294 1999
16
Enhancement of the Nipple-Areolar-Complex on Contrast-Enhanced MR Imaging of the Breast. 38
11091660 1998
17
[Intracystic papilloma of the male breast associated with monolateral gynecomastia. Clinicopathological findings in a case]. 38
9638174 1998
18
Cholesterol granuloma of the breast presenting as an intracystic papilloma. 38
9536911 1997
19
Simultaneous Assay of ErbB-2 Protein and Carcinoembryonic Antigen in Cyst Fluid as an Aid in Diagnosing Cystic Lesions of the Breast. 38
11091503 1994
20
Papillary neoplasms of the breast: fine-needle aspiration findings in cystic and solid cases. 38
7924806 1994
21
Intracystic papilloma in male breast: ultrasonography and pneumocystography diagnosis. 38
8478444 1993
22
[Intracystic papilloma of the breast. 3 case reports]. 38
2236700 1990
23
The value of routine cytologic examination of breast cyst fluids. 38
3109184 1987
24
Squamous metaplasia of the breast. An ultrastructural and immunologic evaluation. 38
3898814 1985
25
[Intraductal (intracystic) papilloma of the male breast]. 38
6528760 1984
26
Breast masses in young girls. Report of five cases. 38
7134066 1982
27
The ultrastructure of apocrine cells in intracystic papilloma and fibrocystic disease of the breast. 38
4191043 1970
28
[Intracystic papilloma of the kidney with hemorrhage during correct anticoagulant therapy]. 38
13068805 1953
29
PSEUDOGLANDULAR type of intracystic papilloma. 38
14804064 1951
30
Intracystic papilloma of the breast. 38
19970494 1940
31
Case of Intracystic Papilloma of an Accessory Thyroid. 38
30437499 1908

Variations for Intracystic Papillary Adenoma

Expression for Intracystic Papillary Adenoma

Search GEO for disease gene expression data for Intracystic Papillary Adenoma.

Pathways for Intracystic Papillary Adenoma

Pathways related to Intracystic Papillary Adenoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
10.83 PRL PGR ERBB2

GO Terms for Intracystic Papillary Adenoma

Biological processes related to Intracystic Papillary Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of epithelial cell proliferation GO:0050679 8.65 ERBB2
2 mammary gland development GO:0030879 8.62 PRL PGR

Molecular functions related to Intracystic Papillary Adenoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 identical protein binding GO:0042802 8.8 PGR ERBB2 CEACAM5

Sources for Intracystic Papillary Adenoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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