MCID: INT380
MIFTS: 22

Intraductal Breast Benign Neoplasm

Categories: Cancer diseases

Aliases & Classifications for Intraductal Breast Benign Neoplasm

MalaCards integrated aliases for Intraductal Breast Benign Neoplasm:

Name: Intraductal Breast Benign Neoplasm 12
Intraductal Breast Neoplasm 15

Classifications:



External Ids:

Disease Ontology 12 DOID:3013
NCIt 49 C36083
UMLS 71 C0948967

Summaries for Intraductal Breast Benign Neoplasm

Disease Ontology : 12 A breast benign neoplasm that is located in the breast ducts.

MalaCards based summary : Intraductal Breast Benign Neoplasm, also known as intraductal breast neoplasm, is related to breast intraductal proliferative lesion and enchondroma. An important gene associated with Intraductal Breast Benign Neoplasm is CT45A10 (Cancer/Testis Antigen Family 45 Member A10), and among its related pathways/superpathways are Cytoskeleton remodeling Neurofilaments and Signaling by ERBB4. Affiliated tissues include breast ducts and breast, and related phenotype is neoplasm.

Related Diseases for Intraductal Breast Benign Neoplasm

Diseases related to Intraductal Breast Benign Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 310)
# Related Disease Score Top Affiliating Genes
1 breast intraductal proliferative lesion 32.8 CT45A10 ADH6
2 enchondroma 10.6 IDH2 IDH1
3 adult brain stem glioma 10.5 IDH2 IDH1
4 cytogenetically normal acute myeloid leukemia 10.5 IDH2 IDH1
5 breast adenomyoepithelioma 10.5 KRT5 KRT14
6 intracranial chondrosarcoma 10.5 IDH2 IDH1
7 breast cystic hypersecretory carcinoma 10.5 KRT5 ERBB2
8 periosteal chondrosarcoma 10.5 IDH2 IDH1
9 breast squamous cell carcinoma 10.5 KRT5 ERBB2
10 adult oligodendroglioma 10.5 IDH2 IDH1
11 scirrhous adenocarcinoma 10.5 PGR ERBB2
12 vulva basal cell carcinoma 10.5 KRT5 ERBB2
13 chronic tympanitis 10.5 PGR ESR1
14 pregnancy adenoma 10.5 PGR KRT5
15 basaloid lung carcinoma 10.5 PGR KRT5
16 childhood oligodendroglioma 10.5 IDH2 IDH1
17 bartholin's gland adenoma 10.5 PGR ESR1
18 juxtacortical chondroma 10.5 IDH2 IDH1
19 granulomatous endometritis 10.5 PGR ESR1
20 bartholin's gland benign neoplasm 10.5 PGR ESR1
21 vestibular gland benign neoplasm 10.5 PGR ESR1
22 vaginal glandular tumor 10.5 PGR ESR1
23 laryngeal mucoepidermoid carcinoma 10.5 KRT14 ERBB2
24 lung leiomyoma 10.5 PGR ESR1
25 vulvar syringoma 10.5 PGR ESR1
26 apocrine adenosis of breast 10.5 PGR ERBB2
27 trigonitis 10.5 PGR ESR1
28 cervical clear cell adenocarcinoma 10.5 PGR ESR1
29 adult type testicular granulosa cell tumor 10.5 PGR ESR1
30 interval angle-closure glaucoma 10.5 IDH2 IDH1
31 breast myoepithelial neoplasm 10.5 KRT5 KRT14
32 gemistocytic astrocytoma 10.4 IDH2 IDH1
33 liver leiomyoma 10.4 PGR ESR1
34 epidermolysis bullosa simplex, autosomal recessive 1 10.4 KRT5 KRT14
35 odontoma 10.4 KRT5 KRT14
36 breast adenoid cystic carcinoma 10.4 PGR ERBB2
37 mammographic density 10.4 PGR ESR1
38 ureter squamous cell carcinoma 10.4 KRT7 KRT5
39 bizarre leiomyoma 10.4 PGR ESR1
40 triple-receptor negative breast cancer 10.4 PGR ERBB2
41 inverted transitional papilloma 10.4 KRT7 KRT5
42 adult astrocytic tumour 10.4 IDH2 IDH1
43 ureter adenocarcinoma 10.4 KRT7 KRT5
44 ceruminoma 10.4 KRT7 KRT5
45 malignant acrospiroma 10.4 KRT7 KRT5
46 breast papillomatosis 10.4 IDH2 IDH1 ERBB2
47 urethral villous adenoma 10.4 PGR KRT7
48 mucinous intrahepatic cholangiocarcinoma 10.4 KRT7 IDH1
49 breast intraductal papillomatosis 10.4 PGR IDH2 IDH1
50 microinvasive cervical squamous cell carcinoma 10.4 KRT7 KRT5

Graphical network of the top 20 diseases related to Intraductal Breast Benign Neoplasm:



Diseases related to Intraductal Breast Benign Neoplasm

Symptoms & Phenotypes for Intraductal Breast Benign Neoplasm

MGI Mouse Phenotypes related to Intraductal Breast Benign Neoplasm:

45
# Description MGI Source Accession Score Top Affiliating Genes
1 neoplasm MP:0002006 9.17 ERBB2 ESR1 IDH2 KRT14 MFSD1 PGR

Drugs & Therapeutics for Intraductal Breast Benign Neoplasm

Search Clinical Trials , NIH Clinical Center for Intraductal Breast Benign Neoplasm

Genetic Tests for Intraductal Breast Benign Neoplasm

Anatomical Context for Intraductal Breast Benign Neoplasm

The Foundational Model of Anatomy Ontology organs/tissues related to Intraductal Breast Benign Neoplasm:

19
Breast Ducts

MalaCards organs/tissues related to Intraductal Breast Benign Neoplasm:

40
Breast

Publications for Intraductal Breast Benign Neoplasm

Variations for Intraductal Breast Benign Neoplasm

Expression for Intraductal Breast Benign Neoplasm

Search GEO for disease gene expression data for Intraductal Breast Benign Neoplasm.

Pathways for Intraductal Breast Benign Neoplasm

Pathways related to Intraductal Breast Benign Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.47 KRT7 KRT5 KRT14
2
Show member pathways
11.29 PIK3CA PGR ESR1 ERBB2
3 10.77 PIK3CA IDH2 IDH1 ERBB2
4
Show member pathways
10.27 IDH2 IDH1

GO Terms for Intraductal Breast Benign Neoplasm

Cellular components related to Intraductal Breast Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 keratin filament GO:0045095 8.8 KRT7 KRT5 KRT14

Biological processes related to Intraductal Breast Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cornification GO:0070268 9.5 KRT7 KRT5 KRT14
2 2-oxoglutarate metabolic process GO:0006103 9.37 IDH2 IDH1
3 hemidesmosome assembly GO:0031581 9.26 KRT5 KRT14
4 NADP metabolic process GO:0006739 9.16 IDH2 IDH1
5 isocitrate metabolic process GO:0006102 8.96 IDH2 IDH1
6 glyoxylate cycle GO:0006097 8.62 IDH2 IDH1

Molecular functions related to Intraductal Breast Benign Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.96 IDH2 IDH1
2 isocitrate dehydrogenase activity GO:0004448 8.62 IDH2 IDH1

Sources for Intraductal Breast Benign Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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