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MCID: INT004
MIFTS: 26

Intraneural Perineurioma

Categories: Cancer diseases, Neuronal diseases, Rare diseases
Genes Tissues Related diseases Publications Pathways
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Aliases & Classifications for Intraneural Perineurioma

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MalaCards integrated aliases for Intraneural Perineurioma:

Name: Intraneural Perineurioma 12 20 58 15 70

Classifications:

MalaCards categories:
Global: Rare diseases Cancer diseases
Anatomical: Neuronal diseases
See all MalaCards categories (disease lists)
Orphanet: 58  
Rare neurological diseases


External Ids:

Disease Ontology 12 DOID:4696
NCIt 50 C6911
SNOMED-CT 67 768934004
UMLS via Orphanet 71 C1370658
Orphanet 58 ORPHA100003
UMLS 70 C1370658
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Summaries for Intraneural Perineurioma

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GARD : 20 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs. Orpha Number: 100003 Definition Intraneural perineurioma is a rare tumor of cranial and spinal nerves arising from peripheral nerve sheet and composed exclusively or predominantly of cells showing perineurial differentiation. It presents as a localized, tubular or fusiform enlargement of a nerve or nerve segment, usually in the extremities or the trunk, associated with a motor-predominant mononeuropathy including slow, painless, gradual loss of motor function in the involved nerve trunk with muscle weakness and atrophy and, rarely, sensory dysfunction. Cranial nerve involvement is rare.

MalaCards based summary : Intraneural Perineurioma is related to localized hypertrophic neuropathy and perineurioma. An important gene associated with Intraneural Perineurioma is SLC2A1 (Solute Carrier Family 2 Member 1), and among its related pathways/superpathways is Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include tongue, colon and skin.

Wikipedia : 73 An intraneural perineurioma is a rare benign tumor within the sheath of a single nerve that grows but... more...

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Related Diseases for Intraneural Perineurioma

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Diseases related to Intraneural Perineurioma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 128)
# Related Disease Score Top Affiliating Genes
1 localized hypertrophic neuropathy 31.1 S100B MUC1
2 perineurioma 30.9 SLC2A1 S100B S100A1 MUC1 DCAF8
3 neurofibromatosis, type ii 29.9 NF2 DCAF8
4 neurilemmomatosis 29.7 SOX10 NF2
5 neurilemmoma 29.6 SOX10 S100B S100A1 NF2 MUC1
6 neurofibroma 29.3 SOX10 S100B S100A1 NF2 MUC1
7 mononeuropathy 10.4
8 neuropathy 10.3
9 neurofibromatosis 10.3
10 extraneural perineurioma 10.3
11 papillary adenocarcinoma 10.3 SLC2A1 MUC1
12 carpal tunnel syndrome 10.3
13 benign peripheral nerve sheath tumor 10.3
14 papillary tumor of the pineal region 10.3 S100A1 MUC1
15 sclerosing perineurioma 10.3 S100B MUC1
16 reticular perineurioma 10.3 S100B MUC1
17 intracranial cysts 10.3 S100B MUC1
18 aggressive digital papillary adenocarcinoma 10.3 S100B MUC1
19 meningeal melanocytoma 10.3 S100B MUC1
20 cerebral primitive neuroectodermal tumor 10.3 S100B MUC1
21 parachordoma 10.3 S100A1 MUC1
22 chondroid chordoma 10.2 S100A1 MUC1
23 non-functioning pituitary adenoma 10.2 S100B MUC1
24 pericardial mesothelioma 10.2 S100A1 MUC1
25 malignant iris melanoma 10.2 S100B S100A1
26 reticulum cell sarcoma 10.2 S100A1 MUC1
27 cutaneous leiomyosarcoma 10.2 S100B MUC1
28 syringocystadenoma papilliferum 10.2 S100B MUC1
29 ischemic fasciitis 10.2 S100A1 MUC1
30 nephrogenic adenoma 10.2 S100A1 MUC1
31 eccrine porocarcinoma 10.2 S100B MUC1
32 dendritic cell tumor 10.2 S100B MUC1
33 sarcomatoid renal cell carcinoma 10.2 S100A1 MUC1
34 ovarian small cell carcinoma 10.2 S100B MUC1
35 polyneuropathy 10.2
36 neuritis 10.2
37 rare tumor 10.2
38 monophasic synovial sarcoma 10.2 S100B MUC1
39 epidermoid cysts 10.2 S100B S100A1
40 malignant peritoneal mesothelioma 10.2 NF2 MUC1
41 peritoneal mesothelioma 10.2 NF2 MUC1
42 myxoid chondrosarcoma 10.2 S100B MUC1
43 juvenile xanthogranuloma 10.2 S100B S100A1
44 pleomorphic liposarcoma 10.2 S100B MUC1
45 papillary ependymoma 10.2 S100B NF2
46 glomus tumor 10.2 S100A1 MUC1
47 papilloma of choroid plexus 10.1 S100B MUC1
48 cutaneous fibrous histiocytoma 10.1 S100B S100A1
49 clear cell ependymoma 10.1 NF2 MUC1
50 hemangiopericytoma, malignant 10.1 S100B MUC1

Graphical network of the top 20 diseases related to Intraneural Perineurioma:



Diseases related to Intraneural Perineurioma
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Symptoms & Phenotypes for Intraneural Perineurioma

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Drugs & Therapeutics for Intraneural Perineurioma

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Search Clinical Trials , NIH Clinical Center for Intraneural Perineurioma

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Genetic Tests for Intraneural Perineurioma

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Anatomical Context for Intraneural Perineurioma

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MalaCards organs/tissues related to Intraneural Perineurioma:

40
Tongue, Colon, Skin
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Publications for Intraneural Perineurioma

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Articles related to Intraneural Perineurioma:

(show top 50) (show all 85)
# Title Authors PMID Year
1
Intraneural perineurioma of the median nerve at the elbow: A clinical case. 61
33640519 2021
2
Hybrid Schwannoma/Perineurioma: Morphologic Variations and Genetic Profiles. 61
33337633 2020
3
[Intraneural perineurioma of the radial nerve in the spiral canal as the cause of a 6-year progressive paresis of hand and finger extension]. 61
32910223 2020
4
Intraneural perineurioma of the mandible: case series of a rare entity. 61
32868253 2020
5
Intraneural perineurioma with thenar atrophy presenting as congenital absence of thenar muscles. 61
32790117 2020
6
Association of intraneural perineurioma with neurofibromatosis type 2. 61
32529330 2020
7
Facial Nerve Intraneural Perineurioma Masquerading as a Schwannoma. 61
32857124 2020
8
Intraneural perineurioma in neurofibromatosis type 2 with molecular analysis. 61
32271143 2020
9
[Informative value of ultrasound in the diagnosis of intraneural perineurioma]. 61
33095535 2020
10
Clinical and Radiological Follow-up of Intraneural Perineuriomas. 61
30481319 2019
11
Clinicoradiological features of intraneural perineuriomas obviate the need for tissue diagnosis. 61
29192862 2018
12
Intraosseous intraneural perineurioma derived from the inferior alveolar nerve with an abnormality of chromosome 22 and expression of the BCR-ABL fusion gene: report of a case and review of recent literature. 61
30213264 2018
13
Perineurioma of the colon: an uncommon tumor with an unusual location. Report of a case and review of the literature. 61
30546148 2018
14
Intraneural perineuriomas: diagnostic value of magnetic resonance neurography. 61
29094786 2018
15
Intraneural perineurioma: a retrospective study of 19 patients. 61
30637060 2018
16
Anesthesia for a parturient with intraneural perineurioma: A case report. 61
29245354 2017
17
Teaching NeuroImages: Sonographic detection of intraneural perineurioma in therapy-refractory carpal tunnel syndrome. 61
28265045 2017
18
Oral perineurioma: clinicopathologic features from two cases and review of literature. 61
28034640 2017
19
Can Intraneural Perineuriomas Occur Intradurally? An Anatomic Perspective. 61
28173435 2017
20
Intratemporal Intraneural Perineurioma of the Facial Nerve. 61
27668794 2016
21
Intraneural perineurioma of the digital nerve: a case report. 61
26115680 2016
22
Diagnosis and outcome of childhood perineurioma. 61
27086131 2016
23
Case report: Intraneural perineurioma of the sciatic nerve in an adolescent - strategies for revealing the diagnosis. 61
27525083 2016
24
Nerve ultrasound and 3D-MR neurography suggestive of intraneural perineurioma. 61
27001989 2016
25
[Sciatic nerve intraneural perineurioma]. 61
26586011 2015
26
Case report of bilateral relapsing-remitting sciatic nerve palsy during two pregnancies. 61
26545719 2015
27
The almost-invisible perineurioma. 61
26323815 2015
28
Intraneural perineurioma of the skin. 61
24999546 2015
29
[A rare tumor of the median nerve in a young child: Intraneural perineurioma. About one clinical case]. 61
24041664 2014
30
Surgical removal of intraneural perineurioma arising in the brachial plexus using an interfascicular dissection technique. 61
24883285 2014
31
Microscopic intraneural perineurial cell proliferations in patients with neurofibromatosis type 1. 61
24461704 2014
32
Fibrolipomatous hamartoma of the nerve: a clinicopathologic report of 13 cases. 61
24480457 2014
33
Intraneural perineurioma of the sciatic nerve: an under-recognized nerve neoplasm with characteristic MRI findings. 61
24061494 2014
34
Hemi-body port-wine stains and progressive paresis due to territorial perineuriomas. 61
24092235 2014
35
Distinctive manifestations of cutaneous intraneural perineurioma of fingers, compared with typical intraneural perineurioma. 61
24685866 2014
36
Intraneural malignant perineurioma: a case report and review of literature. 61
25120842 2014
37
Intraneural perineurioma affecting multiple nerves: a case report and literature review. 61
25031759 2014
38
Intraneural perineurioma arising in the lateral border of the tongue. 61
24422960 2013
39
Intraneural perineurioma of unilateral radial and median nerves manifesting with long-standing focal amyotrophy in a 14-year-old-boy. 61
24263031 2013
40
Hybrid schwannoma/perineurioma of the spinal nerve: multifocal occurrence, and recurrence as an intraneural perineurioma. 61
23865576 2013
41
Cutaneous intraneural perineurioma: a case report. 61
23221470 2013
42
MRI in hypertrophic mono- and polyneuropathies. 61
22959851 2013
43
Mini-invasive robot-assisted surgery of the brachial plexus: a case of intraneural perineurioma. 61
22638873 2012
44
Claudin-1 and glucose transporter 1 immunolabelling in a canine intraneural perineurioma. 61
22297071 2012
45
MRI of intraneural perineurioma of the brachial plexus. 61
27326273 2012
46
An unusual location of ulnar nerve pathology: a perineurioma of the ulnar nerve in the upper arm. 61
21922473 2011
47
Tumors and tumor-like lesions of peripheral nerves. 61
21072731 2010
48
Intraneural perineurioma of the median nerve: case report and literature review. 61
19876692 2010
49
A case of intraneural perineurioma presenting with monomelic atrophy in a child. 61
20004070 2010
50
Intraneural perineurioma. 61
19766004 2009
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Variations for Intraneural Perineurioma

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Expression for Intraneural Perineurioma

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Search GEO for disease gene expression data for Intraneural Perineurioma.
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Pathways for Intraneural Perineurioma

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Pathways related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
Neural Stem Cell Differentiation Pathways and Lineage-specific Markers 64
10.7 SOX10 SLC2A1 S100B
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GO Terms for Intraneural Perineurioma

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Cellular components related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cortical actin cytoskeleton GO:0030864 8.62 SLC2A1 NF2

Molecular functions related to Intraneural Perineurioma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 S100 protein binding GO:0044548 8.62 S100B S100A1
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Sources for Intraneural Perineurioma

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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