MCID: INT104
MIFTS: 30

Intravascular Papillary Endothelial Hyperplasia

Categories: Rare diseases

Aliases & Classifications for Intravascular Papillary Endothelial Hyperplasia

MalaCards integrated aliases for Intravascular Papillary Endothelial Hyperplasia:

Name: Intravascular Papillary Endothelial Hyperplasia 20 70
Masson's Vegetant Intravascular Hemangio-Endothelioma 20
Masson's Pseudoangiosarcoma 20
Masson's Tumor 20

Classifications:



External Ids:

UMLS 70 C0343083

Summaries for Intravascular Papillary Endothelial Hyperplasia

GARD : 20 Intravascular papillary endothelial hyperplasia (IPEH) is a non-cancerous tumor that occurs due to the overgrowth of the cells that line the blood vessels. Symptoms of IPEH may include a soft mass under the skin and reddish-blue coloring on the skin. Other symptoms may depend on the location of the IPEH. The most common areas of the body for IPEH to occur are the head, neck, lower limbs, and fingers. If left untreated, the tumor can cause damage to the tissue around it and become infected. The cause is unknown. Diagnosis is made by imaging studies and a biopsy to remove a piece of the tumor for examination by a pathologist. Treatment usually includes surgery to remove the tumor.

MalaCards based summary : Intravascular Papillary Endothelial Hyperplasia, also known as masson's vegetant intravascular hemangio-endothelioma, is related to angiosarcoma and soft tissue sarcoma. An important gene associated with Intravascular Papillary Endothelial Hyperplasia is VIM (Vimentin), and among its related pathways/superpathways are Signaling events mediated by VEGFR1 and VEGFR2 and Neural Stem Cell Differentiation Pathways and Lineage-specific Markers. Affiliated tissues include endothelial, tongue and bone, and related phenotype is muscle.

Wikipedia : 73 Intravascular papillary endothelial hyperplasia is a rare, benign tumor. It may mimic an angiosarcoma,... more...

Related Diseases for Intravascular Papillary Endothelial Hyperplasia

Diseases related to Intravascular Papillary Endothelial Hyperplasia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 217)
# Related Disease Score Top Affiliating Genes
1 angiosarcoma 31.4 VIM VEGFA
2 soft tissue sarcoma 30.5 VEGFA HIF1A
3 hemangioma 30.5 VIM VEGFA HIF1A ACTC1
4 angiomyolipoma 30.2 VIM ACTC1
5 vascular cancer 30.2 VEGFA SERPINA3
6 pleomorphic adenoma 30.1 VIM ACTC1
7 secretory meningioma 30.1 VIM SERPINA3
8 varicose veins 30.0 VEGFA HIF1A
9 glomus tumor 30.0 VIM ACTC1
10 neurilemmoma 29.9 VIM SERPINA3 ACTC1
11 hemangiopericytoma, malignant 29.7 VIM SERPINA3 ACTC1
12 sarcoma 29.6 VIM VEGFA HIF1A ACTC1
13 meningioma, familial 29.6 VIM VEGFA SERPINA3
14 spindle cell sarcoma 29.5 VIM VEGFA SERPINA3 ACTC1
15 fibroma 29.4 VIM SERPINA3 ACTC1
16 medulloblastoma 29.4 VIM VEGFA HIF1A ACTC1
17 lymphangioma 29.0 VIM VEGFA SERPINA3 ACTC1
18 adenoid cystic carcinoma 28.7 VIM VEGFA SERPINA3 HIF1A ACTC1
19 kaposi sarcoma 10.4
20 hemangioendothelioma 10.4
21 pyogenic granuloma 10.4
22 arteriovenous malformation 10.4
23 exophthalmos 10.4
24 aneurysm 10.4
25 cavernous hemangioma 10.3
26 intracranial aneurysm 10.2
27 fibromatosis 10.1 VIM ACTC1
28 lymphangiectasis 10.1 VIM ACTC1
29 glomangiomyoma 10.1 VIM ACTC1
30 benign metastasizing leiomyoma 10.1 VIM ACTC1
31 angiocentric glioma 10.1 VIM ACTC1
32 cutaneous leiomyosarcoma 10.1 VIM ACTC1
33 mucinous cystadenocarcinoma 10.1 VIM ACTC1
34 parachordoma 10.1 VIM ACTC1
35 angiolipoma 10.1 VIM ACTC1
36 glomangioma 10.1 VIM ACTC1
37 spindle cell lipoma 10.1 VIM ACTC1
38 reticulum cell sarcoma 10.1 VIM ACTC1
39 ossifying fibromyxoid tumor 10.1 VIM ACTC1
40 polymorphous low-grade adenocarcinoma 10.1 VIM ACTC1
41 granulosa cell tumor of the ovary 10.1 VIM ACTC1
42 dendritic cell tumor 10.1 VIM ACTC1
43 fasciitis 10.1 VIM ACTC1
44 spiradenoma 10.1 VIM ACTC1
45 chondromyxoid fibroma 10.1 VIM ACTC1
46 adenofibroma 10.1 VIM ACTC1
47 epithelial-myoepithelial carcinoma 10.1 VIM ACTC1
48 myoepithelial carcinoma 10.1 VIM ACTC1
49 perineurioma 10.1 VIM ACTC1
50 sarcomatoid mesothelioma 10.1 VIM ACTC1

Graphical network of the top 20 diseases related to Intravascular Papillary Endothelial Hyperplasia:



Diseases related to Intravascular Papillary Endothelial Hyperplasia

Symptoms & Phenotypes for Intravascular Papillary Endothelial Hyperplasia

MGI Mouse Phenotypes related to Intravascular Papillary Endothelial Hyperplasia:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 8.92 ACTC1 HIF1A VEGFA VIM

Drugs & Therapeutics for Intravascular Papillary Endothelial Hyperplasia

Search Clinical Trials , NIH Clinical Center for Intravascular Papillary Endothelial Hyperplasia

Genetic Tests for Intravascular Papillary Endothelial Hyperplasia

Anatomical Context for Intravascular Papillary Endothelial Hyperplasia

MalaCards organs/tissues related to Intravascular Papillary Endothelial Hyperplasia:

40
Endothelial, Tongue, Bone, Adrenal Gland, Breast, Pineal, Small Intestine

Publications for Intravascular Papillary Endothelial Hyperplasia

Articles related to Intravascular Papillary Endothelial Hyperplasia:

(show top 50) (show all 273)
# Title Authors PMID Year
1
A RARE CASE OF MEDIASTINAL MASSON'S TUMOR MIMICKING A THYMOMA. 61
33794162 2021
2
Spinal intravascular papillary endothelial hyperplasia in an infant. 61
33416937 2021
3
Intravascular papillary endothelial hyperplasia of the finger: a case of Masson's tumor. 61
33628865 2021
4
Cervicothoracic 'no man's land': an unusual location of intravascular papillary endothelial hyperplasia in the supraclavicular fossa presenting a surgical challenge. 61
33608343 2021
5
Intravascular Cutaneous Disorders. A Clinicopathologic Review. 61
32618704 2021
6
Intravascular papillary endothelial hyperplasia in the oral mucosa and jawbones: A collaborative study of 20 cases and a systematic review. 61
33188642 2021
7
Intravascular papillary endothelial hyperplasia (Masson's tumor) of maxillary sinus. 61
33349593 2020
8
Myriad pillars formed by intussusceptive angiogenesis as the basis of intravascular papillary endothelial hyperplasia (IPEH). IPEH is intussusceptive angiogenesis made a lesion. 61
33336356 2020
9
Intravascular papillary endothelial hyperplasia in the mandible: a case report. 61
33233959 2020
10
Intravascular Papillary Endothelial Hyperplasia as a Cause of Reversible Vision Loss. 61
33235177 2020
11
Vulvar intravascular papillary endothelial hyperplasia or Masson's tumor: A case report. 61
32874931 2020
12
Intussusceptive angiogenesis and its counterpart intussusceptive lymphangiogenesis. 61
32329808 2020
13
Intravascular Papillary Endothelial Hyperplasia of the Maxillary Sinus in Patient with Tricuspid Atresia. 61
31473939 2020
14
Petroclival intravascular papillary endothelial hyperplasia with psammoma body-like structures. 61
31802551 2020
15
Intravascular papillary endothelial hyperplasia of the periocular region. 61
31691620 2020
16
Masson tumor as a neck mass. 61
31378706 2020
17
Masson's tumor of the breast: Rare differential for new or recurrent breast cancer-Case report, pathology, and review of the literature. 61
31538368 2020
18
Sinusoidal hemangioma with secondary intravascular papillary endothelial hyperplasia. 61
32317533 2020
19
Intravascular Papillary Endothelial Hyperplasia: A Rare Cause of Painful Proptosis. 61
32282639 2020
20
Participation of Intussusceptive Angiogenesis in the Morphogenesis of Lobular Capillary Hemangioma. 61
32193418 2020
21
Intravascular Papillary Endothelial Hyperplasia of the Pineal Region: A Case Report and Review of the Literature. 61
31525486 2020
22
Masson's Tumor of the Hand: An Uncommon Histopathological Entity. 61
32274236 2020
23
Intravascular Papillary Endothelial Hyperplasia of the Orbit: A Case of Masson's Tumor. 61
31903303 2019
24
Intravascular Papillary Endothelial Hyperplasia in the Coronary Artery: An Unusual Cause of Massive Myocardial Infarction in Hypoplastic Left Heart Syndrome. 61
31084387 2019
25
Masquerading dacryocystitis. 61
31908822 2019
26
Acquired Asymptomatic Blue Tongue: A Report of Exogenous Agent-associated Tongue Dyschromia and Review of Blue Tongue Etiologies. 61
31890441 2019
27
Intussusceptive Lymphangiogenesis in Lymphatic Malformations/Lymphangiomas. 61
31228317 2019
28
Masson's tumor presenting as a left frontal intraparenchymal hemorrhage resulting in severe expressive aphasia during pregnancy: case report. 61
31675720 2019
29
Intravascular Papillary Endothelial Hyperplasia of the Vocal Cord: A Case Report and Review of the Literature. 61
31712548 2019
30
Intravascular Papillary Endothelial Hyperplasia With a Phlebolith of the Tongue: A Potential Pitfall. 61
31104526 2019
31
Masson tumor (intravascular papillary endothelial hyperplasia) arising in a superficial temporal artery aneurysm. 61
31517158 2019
32
Masson's tumor (intravascular papillary endothelial hyperplasia). 61
31777368 2019
33
Huge central intravascular papillary endothelial hyperplasia of the mandible: a case report and review of the literature. 61
31508349 2019
34
Intravascular papillary endothelial hyperplasia occurring in the foot: A case report and review of literature. 61
31305445 2019
35
Spinal intravascular papillary endothelial hyperplasia. Case report and review of the literature. 61
30964346 2019
36
Masson's Hemangioma Mimicking As Leaking Aortic Pseudoaneurysm: An Extremely Rare Presentation. 61
31529430 2019
37
Intravascular papillary endothelial hyperplasia (Masson's hemangioma) of the face. 61
30703866 2019
38
Intravascular papillary endothelial hyperplasia along the intrinsic muscle after hand contusion injury: Report of two cases. 61
30292474 2019
39
Multiple Intravascular Papillary Endothelial Hyperplasia of Bone Mimicking Malignancy on 99mTc-MDP Bone Scan and 18F-FDG PET/CT. 61
30371572 2019
40
The role of differential diagnosis in intravascular papillary endothelial hyperplasia of the sinonasal cavity mimicking angiosarcoma: A case report. 61
30655892 2019
41
Masson's tumor of the kidney: a case report. 61
30577814 2018
42
Intravascular papillary endothelial hyperplasia in the lower labial mucosa mimicking a mucocele. 61
30895153 2018
43
Intravascular Papillary Endothelial Hyperplasia (Masson's Tumor) Within Cauda Equina. 61
30656267 2018
44
A Case of Masson's Tumor of the Penis Presenting as Chronic Pelvic Pain Syndrome. 61
29549674 2018
45
Masson's Hemangioma of the Cheek: A Case Report. 61
29977863 2018
46
Masson's tumor of the pineal region: case report. 61
28777021 2018
47
Staged Management of Intracranial Masson Tumor: An Unexpected Gauntlet: Case Report and Review of the Literature. 61
29550594 2018
48
Masson's Hemangioma of the Urethra: A Case Report. 61
29892154 2018
49
Sinusoidal hemangioma and intravascular papillary endothelial hyperplasia: Interrelated processes that share a histogenetic piecemeal angiogenic mechanism. 61
29486986 2018
50
Intravascular Papillary Endothelial Hyperplasia (Masson's Tumor) Involving the Knee Synovium. 61
30167406 2018

Variations for Intravascular Papillary Endothelial Hyperplasia

Expression for Intravascular Papillary Endothelial Hyperplasia

Search GEO for disease gene expression data for Intravascular Papillary Endothelial Hyperplasia.

Pathways for Intravascular Papillary Endothelial Hyperplasia

GO Terms for Intravascular Papillary Endothelial Hyperplasia

Cellular components related to Intravascular Papillary Endothelial Hyperplasia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 platelet alpha granule lumen GO:0031093 8.62 VEGFA SERPINA3

Biological processes related to Intravascular Papillary Endothelial Hyperplasia according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 cytokine-mediated signaling pathway GO:0019221 9.54 VIM VEGFA HIF1A
2 regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061418 9.51 VEGFA HIF1A
3 positive regulation of endothelial cell proliferation GO:0001938 9.49 VEGFA HIF1A
4 positive regulation of blood vessel endothelial cell migration GO:0043536 9.48 VEGFA HIF1A
5 outflow tract morphogenesis GO:0003151 9.46 VEGFA HIF1A
6 lactation GO:0007595 9.43 VEGFA HIF1A
7 muscle filament sliding GO:0030049 9.4 VIM ACTC1
8 dopaminergic neuron differentiation GO:0071542 9.32 VEGFA HIF1A
9 positive regulation of neuroblast proliferation GO:0002052 9.26 VEGFA HIF1A
10 positive regulation of gene expression GO:0010628 9.26 VIM VEGFA HIF1A ACTC1
11 camera-type eye morphogenesis GO:0048593 9.16 VEGFA HIF1A
12 positive regulation of transcription from RNA polymerase II promoter in response to hypoxia GO:0061419 8.62 VEGFA HIF1A

Sources for Intravascular Papillary Endothelial Hyperplasia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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