Invasive Malignant Thymoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Sources

Aliases & Classifications for Invasive Malignant Thymoma

MalaCards integrated aliases for Invasive Malignant Thymoma:

Name: Invasive Malignant Thymoma ¹² ¹⁵

Invasive Thymoma and Thymic Carcinoma ⁷⁰

Thymoma Malignant Invasive ¹²

Infiltrating Thymoma ¹²

Classifications:

MalaCards categories:
Global: Cancer diseases Rare diseases Genetic diseases
Anatomical: Immune diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:3283

NCIt ⁵⁰ C6453

UMLS ⁷⁰ C0278846

Sources

Summaries for Invasive Malignant Thymoma

MalaCards based summary : Invasive Malignant Thymoma, also known as invasive thymoma and thymic carcinoma, is related to thymoma and thymoma, familial. An important gene associated with Invasive Malignant Thymoma is PTMA (Prothymosin Alpha), and among its related pathways/superpathways are NF-kappaB Signaling and Cell adhesion molecules. The drugs Pembrolizumab and Antineoplastic Agents, Immunological have been mentioned in the context of this disorder. Affiliated tissues include breast, skin and bone, and related phenotypes are cellular and hematopoietic system

Sources

Related Diseases for Invasive Malignant Thymoma

Diseases in the Thymoma family:

Thymoma, Familial	Invasive Malignant Thymoma
Type C Thymoma	Malignant Type Ab Thymoma
Malignant Type a Thymoma	Thymoma Type a
Thymoma Type B	Thymoma Type Ab

Diseases related to Invasive Malignant Thymoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 261)

#	Related Disease	Score	Top Affiliating Genes
1	thymoma	30.8	TMSB4X PTMA CD8A
2	thymoma, familial	10.4
3	thymic carcinoma	10.4
4	b cell prolymphocytic leukemia	10.3	CD38 CD19
5	refractory hematologic cancer	10.3	CD38 CD19
6	mental retardation, autosomal dominant 36	10.3	CD38 CD19
7	mental retardation, autosomal dominant 33	10.3	MME CD38
8	adult lymphoma	10.3	MME CD19
9	granulomatous myositis	10.3	PTHLH CD8A
10	aids phobia	10.3	MME CD4
11	orbital cellulitis	10.2	MME CD4
12	acute orbital inflammation	10.2	MME CD4
13	lobomycosis	10.2	CD4 CD19
14	cork-handlers' disease	10.2	CD8A CD4
15	necrotic uveal melanoma	10.2	CD8A CD4
16	vaginal cancer	10.2	MME CD4
17	early yaws	10.2	CD8A CD4
18	ventilation pneumonitis	10.2	CD8A CD4
19	diffuse infiltrative lymphocytosis syndrome	10.2	CD8A CD4
20	latent syphilis	10.2	CD8A CD4
21	polyclonal hypergammaglobulinemia	10.2	MME CD4
22	type 1 diabetes mellitus 23	10.2	CD8A CD4
23	autoimmune lymphoproliferative syndrome, type iia	10.2	CD8A CD4
24	parapsoriasis	10.2	CD8A CD4
25	gastroduodenitis	10.2	CD8A CD4
26	duodenitis	10.2	CD8A CD4
27	primary syphilis	10.2	CD8A CD4
28	norwegian scabies	10.2	CD8A CD4
29	skin sarcoidosis	10.2	CD8A CD4
30	metal allergy	10.2	CD8A CD4
31	variola major	10.2	CD8A CD4
32	follicular mucinosis	10.2	CD8A CD4
33	tertiary syphilis	10.2	CD8A CD4
34	spongiotic dermatitis	10.2	CD8A CD4
35	acute retinal necrosis syndrome	10.2	CD8A CD4
36	oral tuberculosis	10.2	CD8A CD4
37	cerebritis	10.2	CD8A CD4
38	west nile encephalitis	10.2	CD8A CD4
39	granulomatous hepatitis	10.2	CD8A CD4
40	exanthema subitum	10.2	CD8A CD4
41	immunodeficiency 36	10.2	CD8A CD4
42	viral exanthem	10.2	CD8A CD4
43	secondary syphilis	10.2	CD8A CD4
44	acute interstitial pneumonia	10.2	CD8A CD4
45	glanders	10.2	CD8A CD4
46	oral hairy leukoplakia	10.2	CD8A CD4
47	superficial basal cell carcinoma	10.2	CD8A CD4
48	esophageal candidiasis	10.2	CD8A CD4
49	myeloid and lymphoid neoplasms associated with fgfr1 abnormalities	10.2	CD8A CD4
50	spleen cancer	10.2	MME CD19

Graphical network of the top 20 diseases related to Invasive Malignant Thymoma:

Sources

Symptoms & Phenotypes for Invasive Malignant Thymoma

MGI Mouse Phenotypes related to Invasive Malignant Thymoma:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	cellular	MP:0005384	9.85	CD19 CD34 CD38 CD4 CD8A MME
2	hematopoietic system	MP:0005397	9.61	CD19 CD34 CD38 CD4 CD8A PTH
3	immune system	MP:0005387	9.32	CD19 CD34 CD38 CD4 CD8A MME

Sources

Drugs & Therapeutics for Invasive Malignant Thymoma

Drugs for Invasive Malignant Thymoma (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 16)

#

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

1

Pembrolizumab

Approved

Phase 4

1374853-91-4

2

Antineoplastic Agents, Immunological

Phase 4

3

Octreotide

Approved, Investigational

Phase 2

83150-76-9

383414 6400441

Synonyms:

(4R,7S,10S,13R,16S,19R)-10-(4-aminobutyl)-19-[[(2R)-2-amino-3-phenylpropanoyl]amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-[(1R)-1-hydroxyethyl]-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

(4R,7S,10S,13R,16S,19R)-19-{[(2R)-2-amino-1-hydroxy-3-phenylpropylidene]amino}-10-(4-aminobutyl)-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-6,9,12,15,18-pentahydroxy-7-(1-hydroxyethyl)-13-[(1H-indol-3-yl)methyl]-1,2-dithia-5,8,11,14,17-pentaazacycloicosa-5,8,11,14,17-pentaene-4-carboximidate

10-(4-Aminobutyl)-19-((2-amino-3-phenylpropanoyl)amino)-16-benzyl-7-(1-hydroxyethyl)-N-(2-hydroxy-1-(hydroxymethyl)propyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentaa

10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-(1,3-dihydroxybutan-2-yl)-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

10-(4-aminobutyl)-19-[(2-amino-3-phenylpropanoyl)amino]-16-benzyl-N-[(2R,3R)-1,3-dihydroxybutan-2-yl]-7-(1-hydroxyethyl)-13-(1H-indol-3-ylmethyl)-6,9,12,15,18-pentaoxo-1,2-dithia-5,8,11,14,17-pentazacycloicosane-4-carboxamide

79517-01-4 (acetate salt)

83150-76-9

AC1L1GVU

AC1L8LCD

AC1L9M4X

C07306

C5H12O2.C4H10

CHEBI:427278

CHEBI:611465

CHEMBL1680

CID383414

CID448601

CID54374

Compound 201 995

Compound 201995

Compound 201-995

D00442

D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-L-threoninol cyclic (2-7)-disulfide

D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2->7)-disulfide

D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-((1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl)-L-cysteinamide cyclic (2-7)-disulfide

DRG-0115

HMS2090C09

HS-2020

L000453

L-Cysteinamide, D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L- threonyl-N-(2-hydroxy-1-(hydroxymethyl)propyl)-, cyclic (2->7)-disulfide, (R-(R*

Longastatin

LS-177735

LS-187135

NCGC00181796-01

nchembio.184-comp3

NCI60_025753

Octreotida

Octreotida [Spanish]

Octreotide

Octreotide (USAN/INN)

Octreotide [USAN:INN:BAN]

Octreotide acetate

Octreotide acetate salt

Octreotide Acetate Salt

Octreotide-LAR

Octreotidum

Octreotidum [Latin]

Octrotide

SAN 201-995

Sandostatin

Sandostatine

Sandoz 201 995

Sandoz 201995

Sandoz 201-995

SM 201-995

SMS 201-995

SMS-201-995

UNII-RWM8CCW8GP

zacycloicosane-4-carboxamide acetate

4

Prednisone

Approved, Vet_approved

Phase 2

53-03-2

5865

Synonyms:

(1S,2R,10S,11S,14R,15S)-14-hydroxy-14-(2-hydroxyacetyl)-2,15-dimethyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-3,6-diene-5,17-dione

(8S,9S,10R,13S,14S,17R)-17-hydroxy-17-(2-hydroxyacetyl)-10,13-dimethyl-6,7,8,9,12,14,15,16-octahydrocyclopenta[a]phenanthrene-3,11-dione

(8xi,9xi,14xi)-17,21-dihydroxypregna-1,4-diene-3,11,20-trione

.delta. E

.delta.(sup1)-Cortisone

.delta.1-Cortisone

.delta.1-Dehydrocortisone

.delta.-Cortelan

.delta.-Cortisone

.delta.-Cortone

.delta.-E

.delta.sone

1,2-Dehydrocortisone

1,4-Pregnadiene-17.alpha.,21-diol-3,11,20-trione

1,4-Pregnadiene-17a,21-diol-3,11,20-trione

1,4-Pregnadiene-17alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17-alpha,21-diol-3,11,20-trione

1,4-Pregnadiene-17α,21-diol-3,11,20-trione

17,21-Dihydroxypregna-1,4-diene-3,11,20-trione

17alpha,21-Dihydroxy-1,4-pregnadiene-3,11,20-trione

1-Cortisone

1-Dehydrocortisone

53-03-2

68-59-7

81552_FLUKA

AC-11112

AC1L1LB2

AC1Q29EZ

Acis brand OF prednisone

ACon0_000082

ACon1_000297

Acsis, prednison

Adasone

AI3-52939

Ancortone

Apo-prednisone

Apo-Prednisone

Apotex brand OF prednisone

Aventis brand OF prednisone

Betapar

Bicortone

Bio-0649

BPBio1_000323

BRD-K85883481-001-04-2

BSPBio_000293

C07370

C21H26O5

Cartancyl

CCRIS 2646

CHEBI:8382

CHEMBL635

CID5865

Colisone

Cortan

Cortancyl

Cortidelt

Cotone

CPD001227202

Cutason

Dacorten

Dacortin

DB00635

Decortancyl

Decortin

Decortisyl

Dehydrocortisone

Dekortin

Delcortin

Dellacort

Dellacort A

delta cortelan

Delta Cortelan

Delta E

Delta E.

delta(sup 1)-Cortisone

delta(sup 1)-Dehydrocortisone

delta-1-Cortisone

delta-1-Dehydrocortisone

Delta-cortelan

Delta-Cortelan

Deltacortene

delta-Cortisone

Deltacortisone

Delta-cortisone

delta-Cortone

Deltacortone

Delta-cortone

Delta-dome

Delta-Dome

Deltasone

Deltasone, Liquid Pred, Orasone, Adasone, Deltacortisone,Prednisone

Deltison

Deltisona

Deltisone

Deltra

Diadreson

Di-Adreson

Diba brand OF prednisone

Econosone

EINECS 200-160-3

Encorton

Encortone

Enkortolon

Enkorton

Fawns and mcallan brand OF prednisone

Fernisone

Ferring brand OF prednisone

Fiasone

GALENpharma brand OF prednisone

Halsey drug brand OF prednisone

Hexal brand OF prednisone

HMS1568O15

HMS2090J13

Hoechst brand OF prednisone

Hostacortin

HSDB 3168

ICN brand OF prednisone

Incocortyl

In-Sone

Juvason

Kortancyl

Lichtenstein brand OF prednisone

Liquid pred

Liquid Pred

Lisacort

LMST02030180

Lodotra

LS-1325

MEGxm0_000443

Me-Korti

Merck brand OF prednisone

Merz brand OF prednisone

Metacortandracin

Meticorten

Meticorten (Veterinary)

Metrevet (Veterinary)

Mibe brand OF prednisone

MLS001061265

MLS001304073

MLS001335907

MLS001335908

MLS002154191

MLS002207083

MolPort-001-740-041

NCGC00090766-01

NCGC00090766-02

NCGC00090766-03

NCI60_000008

NCI-C04897

Nisona

Nizon

Novoprednisone

NSC 10023

NSC10023

Nurison

Orasone

Origen Prednisone

P1276

P6254_SIGMA

Panafcort

Panasol

Paracort

Parmenison

Pehacort

Pharmacia brand OF prednisone

PRD

Precort

Predeltin

Predni tablinen

Prednicen-M

Prednicorm

Prednicort

Prednicot

Prednidib

Prednilonga

Predniment

Prednison

Prednison acsis

Prednison galen

Prednison hexal

Prednisona

Prednisona [INN-Spanish]

Prednisone

Prednisone [INN:BAN]

Prednisone Intensol

Prednisonum

Prednisonum [INN-Latin]

Prednitone

Prednizon

Prednovister

Presone

Prestwick_405

Prestwick0_000077

Prestwick1_000077

Prestwick2_000077

Prestwick3_000077

Pronison

Pronisone

Rectodelt

Retrocortine

S1622_Selleck

SAM002264641

Schering-plough brand OF prednisone

Seatrace brand OF prednisone

Servisone

SK-Prednisone

SMR000718760

SMR001227202

Solvay brand OF prednisone

Sone

SPBio_002214

Sterapred

Supercortil

Trommsdorff brand OF prednisone

U 6020

Ultracorten

Ultracortene

UNII-VB0R961HZT

Winpred

WLN: L E5 B666 CV OV AHTTT&J A1 E1 FV1Q FQ

Wojtab

Zenadrid

Zenadrid (veterinary)

Zenadrid [veterinary]

ZINC03875357

5

Paclitaxel

Approved, Vet_approved

Phase 2

33069-62-4

36314

Synonyms:

(2AR-(2aalpha,4b,4abeta,6b,9a(a r*,betas*),11a,12a,12balpha))-b-(benzoylamino)-a-hydroxybenzenepropanoate 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4b,4abeta,6b,9a(a r*,betas*),11a,12a,12balpha))-b-(benzoylamino)-a-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoate 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4beta,4abeta,6beta,9alpha(alpha r*,betas*),11alpha,12alpha,12balpha))-beta-(benzoylamino)-alpha-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4β,4abeta,6β,9α(α r*,betas*),11α,12α,12balpha))-β-(benzoylamino)-α-hydroxybenzenepropanoate 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

(2AR-(2aalpha,4β,4abeta,6β,9α(α r*,betas*),11α,12α,12balpha))-β-(benzoylamino)-α-hydroxybenzenepropanoic acid 6,12b-bis(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-4,11-dihydroxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca(3,4)benz(1,2-b)oxet-9-yl ester

12-benzoate, 9-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

157069-30-2

33069-62-4

5b,20-Epoxy-1,2-a,4,7b,10b,13a-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5b,20-Epoxy-1,2-a,4,7b,10b,13a-hexahydroxytax-11-en-9-one 4,10-diacetic acid 2-benzoic acid 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5beta,20-Epoxy-1,2-alpha,4,7beta,10beta,13alpha-hexahydroxytax-11-en-9-one 4,10-diacetic acid 2-benzoic acid 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5Β,20-epoxy-1,2-α,4,7β,10β,13α-hexahydroxytax-11-en-9-one 4,10-diacetate 2-benzoate 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

5Β,20-epoxy-1,2-α,4,7β,10β,13α-hexahydroxytax-11-en-9-one 4,10-diacetic acid 2-benzoic acid 13-ester with (2R,3S)-N-benzoyl-3-phenylisoserine

7 Epi taxol

7,11-Methano-1H-cyclodeca[3,4]benz[1,2-b]oxete, benzenepropanoic acid deriv.

7,11-Methano-5H-cyclodeca[3,4]benz[1,2-b]oxete,benzenepropanoic acid deriv.

7-epi-Paclitaxel

7-Epipaclitaxel

7-Epi-paclitaxel

7-epi-Taxol

7-Epitaxol

7-Epi-taxol

AB00513812

ABI 007

abi-007

ABI007

ABI-007

Abraxane

Abraxane (TN)

Abraxane I.V. Suspension

Abraxis BioScience brand of albumin-bound paclitaxel

AC1L1IOG

AC1L1VJI

AC1L9AVF

AC-675

ACon1_002231

albumin-bound paclitaxel

Ambotz33069-62-4

ANX-513

Anzatax

Asotax

BIDD:PXR0046

Bio-0076

Bio1_000362

Bio1_000851

Bio1_001340

Bio2_000416

Bio2_000896

BMS 181339-01

BMS-181339

BMS-181339-01

BPBio1_000320

BRD-A23723433-001-01-2

BRD-A28746609-001-04-0

BRD-K62008436-001-03-1

Bris taxol

Bristaxol

BSPBio_000290

BSPBio_001152

BSPBio_002614

C07394

C466458

C47H51NO14

Capxol

CCRIS 8143

CHEBI:103439

CHEBI:45863

CHEMBL100910

CHEMBL418410

CHEMBL48

CID36314

CID441276

CID4666

CID6713921

CID6915727

cMAP_000068

CPD-8718

D00491

DB01229

DHP-107

DHP-208

DivK1c_000441

DRG-0190

DTS-301

Ebetaxel

EmPAC

Epitaxol

EU-0101201

Genaxol

Genetaxyl

Genexol

Genexol-PM

HMS1362J13

HMS1568O12

HMS1792J13

HMS1922K08

HMS1990J13

HMS2090D07

HMS2093K15

HMS501G03

HSDB 6839

I06-0014

IDI1_000441

IDI1_002171

Intaxel

KBio1_000441

KBio2_000492

KBio2_002016

KBio2_002509

KBio2_003060

KBio2_004584

KBio2_005077

KBio2_005628

KBio2_007152

KBio2_007645

KBio3_000903

KBio3_000904

KBio3_001834

KBio3_002987

KBioGR_000492

KBioGR_001893

KBioGR_002509

KBioSS_000492

KBioSS_002016

KBioSS_002517

LipoPac

LMPR0104390001

Lopac0_001201

LS-31070

MBT 0206

MEGxp0_001940

Micellar Paclitaxel

Mitotax

MLS000863266

MLS001077297

MLS002154218

MLS002172439

MLS002695976

MolPort-001-742-627

MolPort-003-665-783

MolPort-003-932-365

MPI-5018

nab-paclitaxel

Nanotaxel

NCGC00024995-02

NCGC00024995-03

NCGC00024995-04

NCGC00024995-05

NCGC00024995-06

NCGC00024995-07

NCGC00164367-01

NCGC00164367-02

NCGC00164367-03

nchembio.188-comp1

nchembio.2007.34-comp9

nchembio.215-comp9

nchembio853-comp6

NCI60_000601

Neuro_000060

NINDS_000441

NK 105

Nova-12005

NP-010981

NSC 125973

NSC125973

NSC-125973

NSC358882

OAS-PAC-100

OncoGel

Onxal

Onxol

Onxol, Taxol, Nov-Onxol, Paclitaxel

P1632

Paclical

Pacligel

paclitaxel

Paclitaxel

Paclitaxel (JAN/USP)

Paclitaxel (JAN/USP/INN)

Paclitaxel (Taxol)

Paclitaxel [USAN:INN:BAN]

Paclitaxel, (4 alpha)-isomer

Paxceed

Paxene

Paxoral

Plaxicel

Praxel

Prestwick0_000155

Prestwick1_000155

Prestwick2_000155

Prestwick3_000155

Probes2_000350

QW 8184

S1150_Selleck

S-8184 Paclitaxel Injectable Emulsion

SDCCGMLS-0066823.P001

SDP-013

SMP1_000228

SMR000394086

SMR000857385

SPBio_000943

SPBio_002229

Spectrum_001536

SPECTRUM1503908

Spectrum2_000872

Spectrum3_001057

Spectrum4_001197

Spectrum5_001491

ST50306996

T 7402

T1912_SIGMA

T7191_SIGMA

T7402_SIGMA

TA1

TaxAlbin

Taxol

TAXOL

TAXOL (TN)

Taxol a

Taxol A

Taxol Konzentrat

TAXOL, 10-EPI,

Taxol, bris

Taxol.RTM. (Registered Trademark)

TXL

UNII-P88XT4IS4D

UPCMLD-DP108:001

UPCMLD-DP108:002

Vascular Wrap

weekly paclitaxel

Xorane

Yewtaxan

6

Cisplatin

Approved

Phase 2

15663-27-1

84093 441203 2767

Synonyms:

(SP-4-1)-diamminedichloridoplatinum

(SP-4-1)-diamminedichloroplatinum

(SP-4-2)-diamminedichloridoplatinum

(SP-4-2)-diamminedichloroplatinum

Abiplatin

Biocisplatinum

Briplatin

CACP

Carboquone

CDDP

CHEBI:35852

CID441203

Cis Pt II

cis-[PtCl2(NH3)2]

cis-DDP

Cis-DDP

Cis-Diaminedichloroplatinum

cis-diamminedichloridoplatinum(II)

cis-Diamminedichloroplatinum

Cis-Diamminedichloroplatinum

cis-diamminedichloroplatinum(II)

cis-Dichlorodiammineplatinum(II)

Cismaplat

Cisplatin

Cisplatine

cisplatino

Cisplatino

Cisplatinum

Cisplatyl

Citoplationo

CPD0-1392

CPDC

CPDD

DB00515

DDP

DDPT

Diamminedichloroplatinum

EU-0100918

Lederplatin

nchembio773-comp1

Neoplatin

Peyrone's chloride

Peyrone's salt

Plastin

Platamine

Platiblastin

Platidiam

Platinex

Platinol

Platinol-AQ

Platinoxan

Platinum Ammine Chloride

Platinum Ammonium Chloride

Platinum Diamine Dichloride

Randa

trans-DDP

Trans-DDP

Trans-Diaminedichloroplatinum

trans-diamminedichloridoplatinum(II)

Trans-Diamminedichloroplatinum

Trans-Dichlorodiammine Platinum

Trans-Platinumdiammine Dichloride

7

Saracatinib

Investigational

Phase 2

379231-04-6

8

Hormones

Phase 2

9

Gastrointestinal Agents

Phase 2

10

glucocorticoids

Phase 2

11

Hormone Antagonists

Phase 2

12

Antineoplastic Agents, Hormonal

Phase 2

13

Anti-Inflammatory Agents

Phase 2

14

Antimitotic Agents

Phase 2

15

Albumin-Bound Paclitaxel

Phase 2

16

Tubulin Modulators

Phase 2

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Single-Arm Study to Carbo-paclitaxel/ Nab-paclitaxel Combined With Pembrolizumab as the First Line Therapy in Treating Patients With Locally Advanced or Metastatic Invasive Thymoma and Thymic Carcinoma That Cannot Be Removed by Surgery	Recruiting	NCT04554524	Phase 4	Chemotherapy+Pembrolizumab.
2	Phase II Study of Octreotide Treatment of Advanced, Recurrent Thymoma	Completed	NCT00003283	Phase 2	octreotide acetate;prednisone
3	Phase II Trial of AZD0530 for Patients With Relapsed/Refractory Thymic Malignancies (Thymoma and Thymic Carcinoma)	Terminated	NCT00718809	Phase 2	saracatinib
4	A Phase II Study of Paclitaxel and Cisplatin in Previously Untreated, Unresectable Invasive Thymoma or Thymic Carcinoma	Terminated	NCT00818090	Phase 2	paclitaxel and cisplatin

Search NIH Clinical Center for Invasive Malignant Thymoma

Sources

Genetic Tests for Invasive Malignant Thymoma

Sources

Anatomical Context for Invasive Malignant Thymoma

MalaCards organs/tissues related to Invasive Malignant Thymoma:

⁴⁰

Breast, Skin, Bone, Lung, Myeloid, Bone Marrow, Spleen

Sources

Publications for Invasive Malignant Thymoma

Articles related to Invasive Malignant Thymoma:

(show all 13)

#	Title	Authors	PMID	Year
1	En-bloc thymectomy with aortic arch reconstruction under circulatory arrest for invasive malignant thymoma. ⁶¹	Marcano JE...Rice D	32353149	2020
2	Myasthenia gravis associated with invasive malignant thymoma: two case reports and a review of the literature. ⁶¹	Beydoun SR...Rison RA	25312448	2014
3	[Irradiation for invasive malignant thymoma led a remission of refractory minimal change nephrotic syndrome: a case report]. ⁶¹	Okamoto T...Kamata K	20560473	2010
4	Imaging of an invasive malignant thymoma on PET Scan: CT and histopathologic correlation. ⁶¹	Bagga S...Bloch EM	16985366	2006
5	Association of a wide invasive malignant thymoma with myastenia gravis and primary hyperparathyroidism due to parathyroid adenoma: case report and review of the literature. ⁶¹	Triggiani V...Tafaro E	16873103	2006
6	Incidental locally infiltrating malignant thymoma and coronary artery bypass surgery-excision should always be considered. ⁶¹	Mirsadraee S...Kaul P	15854100	2005
7	Severe T- and B-cell immune deficiency associated with malignant thymoma. ⁶¹	Yel L...Gupta S	14692437	2003
8	Thymoma--report of 71 cases and a review. ⁶¹	Verstandig AG...Miller WT	1571088	1992
9	Biochemical characterization of thymic hormones in thymoma tissues. ⁶¹	Low TL	2333664	1990
10	Undifferentiated epithelial-rich invasive malignant thymoma: complete response to cisplatin, vinblastine, and bleomycin therapy. ⁶¹	Dy C...Harguindey S	2450971	1988
11	Aggressive surgical approach for drug-free remission from myasthenia gravis. ⁶¹	Fischer JE...Samaha FJ	3579398	1987
12	Cardiovascular involvement by invasive thymomas. ⁶¹	Shin MS...Perrott WW	865126	1977
13	[On the treatment of invasive malignant thymoma]. ⁶¹	Motoki R...Matsui T	5692541	1968

Sources

Genes for Invasive Malignant Thymoma

Genes related to Invasive Malignant Thymoma (0 elite genes):

(show all 13)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	PTMA	Prothymosin Alpha	Protein Coding	6.09	DISEASES inferred ¹⁵
2	TMSB4X	Thymosin Beta 4 X-Linked	Protein Coding	5.75	DISEASES inferred ¹⁵
3	CD38	CD38 Molecule	Protein Coding	5.25	DISEASES inferred ¹⁵
4	GNAT3	G Protein Subunit Alpha Transducin 3	Protein Coding	5.2	DISEASES inferred ¹⁵
5	MME	Membrane Metalloendopeptidase	Protein Coding	5.08	DISEASES inferred ¹⁵
6	PTHLH	Parathyroid Hormone Like Hormone	Protein Coding	4.81	DISEASES inferred ¹⁵
7	CD19	CD19 Molecule	Protein Coding	4.8	DISEASES inferred ¹⁵
8	CD8A	CD8a Molecule	Protein Coding	4.64	DISEASES inferred ¹⁵
9	CD4	CD4 Molecule	Protein Coding	4.6	DISEASES inferred ¹⁵
10	TSHR	Thyroid Stimulating Hormone Receptor	Protein Coding	3.82	DISEASES inferred ¹⁵
11	PTH	Parathyroid Hormone	Protein Coding	3.78	DISEASES inferred ¹⁵
12	CD34	CD34 Molecule	Protein Coding	3.72	DISEASES inferred ¹⁵
13	TNFRSF25	TNF Receptor Superfamily Member 25	Protein Coding	3.42	DISEASES inferred ¹⁵

Sources

Variations for Invasive Malignant Thymoma

Sources

Expression for Invasive Malignant Thymoma

Search GEO for disease gene expression data for Invasive Malignant Thymoma.

Sources

Pathways for Invasive Malignant Thymoma

Pathways related to Invasive Malignant Thymoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	NF-kappaB Signaling ⁴	12.17	TNFRSF25 CD8A CD38 CD34 CD19
2	Cell adhesion molecules ³⁶	11.83	CD8A CD4 CD34
3	G alpha (s) signalling events ⁶⁵	11.79	TSHR PTHLH PTH GNAT3
4	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell ⁶⁵	11.76	CD8A CD34 CD19
5	Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.7	MME CD8A CD4 CD38 CD34 CD19
6	Mesenchymal Stem Cell Differentiation Pathways and Lineage-specific Markers ⁶⁴	11.59	PTH CD34 CD19
7	Innate Lymphoid Cell Differentiation Pathways ⁶⁴	11.48	CD8A CD4 CD34
8	Hematopoietic cell lineage ³⁶	11.43	MME CD8A CD4 CD38 CD34 CD19
9	Primary immunodeficiency ³⁶	11.12	CD8A CD4 CD19
10	Dendritic Cells Developmental Lineage Pathway ⁶⁴	10.97	MME CD8A CD4 CD38 CD34 CD19

Sources

GO Terms for Invasive Malignant Thymoma

Cellular components related to Invasive Malignant Thymoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	external side of plasma membrane	GO:0009897	9.46	CD8A CD4 CD34 CD19
2	cell surface	GO:0009986	9.35	TSHR MME CD4 CD38 CD34
3	integral component of plasma membrane	GO:0005887	9.17	TSHR TNFRSF25 MME CD8A CD4 CD34

Biological processes related to Invasive Malignant Thymoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	signal transduction	GO:0007165	9.7	TSHR TNFRSF25 PTHLH GNAT3 CD4 CD38
2	adenylate cyclase-activating G protein-coupled receptor signaling pathway	GO:0007189	9.43	TSHR PTHLH PTH
3	negative regulation of chondrocyte differentiation	GO:0032331	9.37	PTHLH PTH
4	response to vitamin D	GO:0033280	9.32	PTH CD4
5	cell surface receptor signaling pathway	GO:0007166	9.26	TSHR TNFRSF25 CD8A CD4
6	cAMP metabolic process	GO:0046058	8.62	PTHLH PTH

Molecular functions related to Invasive Malignant Thymoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	peptide hormone receptor binding	GO:0051428	8.62	PTHLH PTH

Sources

Sources for Invasive Malignant Thymoma

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GARD

²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 20-May-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ Tocris

⁷⁰ UMLS

⁷¹ UMLS via Orphanet

⁷² UniProtKB/Swiss-Prot

⁷³ Wikipedia