MCID: INV018
MIFTS: 25

Invasive Mole

Categories: Rare diseases, Reproductive diseases

Aliases & Classifications for Invasive Mole

MalaCards integrated aliases for Invasive Mole:

Name: Invasive Mole 59
Hydatidiform Mole, Invasive 73

Characteristics:

Orphanet epidemiological data:

59
invasive mole
Inheritance: Not applicable; Age of onset: Adult;

Classifications:



External Ids:

Orphanet 59 ORPHA99925
UMLS via Orphanet 74 C0008493
ICD10 via Orphanet 34 D39.2
UMLS 73 C0008493

Summaries for Invasive Mole

MalaCards based summary : Invasive Mole, also known as hydatidiform mole, invasive, is related to gestational trophoblastic tumor and choriocarcinoma. An important gene associated with Invasive Mole is CGB5 (Chorionic Gonadotropin Subunit Beta 5). Affiliated tissues include uterus, lung and placenta, and related phenotypes are menometrorrhagia and high maternal serum chorionic gonadotropin

Wikipedia : 76 Invasive hydatidiform mole, also known as invasive mole and chorioadenoma destruens is a type of... more...

Related Diseases for Invasive Mole

Diseases related to Invasive Mole via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 gestational trophoblastic tumor 11.5
2 choriocarcinoma 10.6
3 hydatidiform mole, recurrent, 1 10.3
4 gestational trophoblastic neoplasm 10.3
5 gestational choriocarcinoma 10.1
6 ovarian hyperstimulation syndrome 10.0
7 hydronephrosis 10.0
8 partial hydatidiform mole 10.0
9 neutropenia 9.8
10 ectopic pregnancy 9.8
11 arteriovenous malformation 9.8
12 nephrotic syndrome 9.8
13 placental site trophoblastic tumor 9.8
14 trophoblastic neoplasm 9.8

Graphical network of the top 20 diseases related to Invasive Mole:



Diseases related to Invasive Mole

Symptoms & Phenotypes for Invasive Mole

Human phenotypes related to Invasive Mole:

59 32
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 menometrorrhagia 59 32 hallmark (90%) Very frequent (99-80%) HP:0400008
2 high maternal serum chorionic gonadotropin 59 32 hallmark (90%) Very frequent (99-80%) HP:0011433

Drugs & Therapeutics for Invasive Mole

Search Clinical Trials , NIH Clinical Center for Invasive Mole

Genetic Tests for Invasive Mole

Anatomical Context for Invasive Mole

MalaCards organs/tissues related to Invasive Mole:

41
Uterus, Lung, Placenta, Kidney, Ovary, Tonsil

Publications for Invasive Mole

Articles related to Invasive Mole:

(show top 50) (show all 74)
# Title Authors Year
1
Partial Invasive Mole with Bilateral Torsion of Theca Lutein Cysts. ( 29353908 )
2018
2
Sudden death due to an invasive mole in a young primigravida: Precipitous presentation masquerading the natural manner. ( 29969941 )
2018
3
Unusual Presentation of Invasive Mole: A Case Report. ( 28377901 )
2017
4
Predictive value of some hematological parameters for non-invasive and invasive mole pregnancies. ( 28093002 )
2017
5
A metastatic invasive mole arising from iatrogenic uterus perforation. ( 29262807 )
2017
6
Sonographic and Power Doppler Evaluation of an Invasive Mole Located in a Cesarean Scar Pregnancy. ( 27353688 )
2016
7
Spontaneous renal hemorrhage caused by invasive mole: a case report. ( 27352577 )
2016
8
Laparoscopic Management of an Invasive Mole Perforating the Uterus. ( 27544879 )
2016
9
Giant invasive mole presenting as a cause of abdominopelvic mass in a perimenopausal woman: An unusual presentation of a rare pathology. ( 27896261 )
2016
10
An invasive mole with bilateral kidney metastases: A case report. ( 26788142 )
2015
11
Invasive mole in a perimenopausal woman: a case report and systematic review. ( 26050078 )
2015
12
Invasive mole of the uterus- a rare case diagnosed by ultrasound: a case report. ( 24791851 )
2014
13
Laparoscopically diagnosed invasive mole presenting as acute hemoperitoneum. ( 25518774 )
2014
14
Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole. ( 25492410 )
2014
15
Unilateral hydronephrosis caused by invasive mole: a case report. ( 24260613 )
2013
16
Sonographic appearance of an advanced invasive mole and associated metastatic thrombus in the inferior vena cava. ( 22238139 )
2013
17
Partial hydatidiform mole progression into invasive mole with lung metastasis following in vitro fertilization. ( 22740971 )
2012
18
An invasive mole presenting with large arteriovenous malformation. ( 23372297 )
2012
19
Homonymous Quadrantanopsia as the First Manifestation of Cerebral Metastasis of Invasive Mole: a case report. ( 22531212 )
2012
20
Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole: report of a case. ( 22355432 )
2011
21
Nephrotic syndrome associated with invasive mole: a case report. ( 20237056 )
2010
22
Four repetitive partial hydatidiform moles followed by malignant transformation to an invasive mole. ( 20846070 )
2010
23
Invasive mole--case report of massive uterine destruction. ( 19125711 )
2008
24
Invasive mole--case report of massive uterine destruction. ( 19145812 )
2008
25
Invasive mole: Indonesian perspective. ( 17939602 )
2007
26
A rare cause of hydronephrosis: invasive mole. ( 16891847 )
2006
27
Invasive mole in a postmenopausal woman. ( 16542659 )
2006
28
Metastatic invasive mole in the urinary bladder. ( 12928567 )
2002
29
Forty-five year's experience of the treatment of choriocarcinoma and invasive mole. ( 9833619 )
1998
30
Forty-five year's experience of the treatment of choriocarcinoma and invasive mole. ( 29645256 )
1998
31
Invasive mole presenting as a spinal extradural tumor: case report. ( 8747969 )
1996
32
Angiographic-guided embolization of metastatic invasive mole. ( 8641630 )
1996
33
Incidence of invasive mole and choriocarcinoma following partial hydatidiform mole. ( 8737309 )
1996
34
A clinical trial on diagnostic scoring system of choriocarcinoma and invasive mole in Vietnam. ( 8590362 )
1995
35
Usefulness of granulocyte colony-stimulating factor on neutropenia in patients of invasive mole and choriocarcinoma. ( 7531835 )
1995
36
Intrapartum uterine rupture in a primiparous patient previously treated for invasive mole. ( 8159371 )
1994
37
Perforation of the uterus by an invasive mole using color Doppler ultrasound: case report. ( 12796904 )
1993
38
Detection of an atypical invasive mole in an ectopic pregnancy by transvaginal color-flow Doppler. ( 8267086 )
1993
39
Immunohistochemical localization of inhibin-activin subunits in hydatidiform mole and invasive mole. ( 8395038 )
1993
40
Prophylactic effect of bestatin on the onset of invasive mole--clinical and fundamental studies. ( 1524955 )
1992
41
Invasive mole and placental site trophoblastic tumor. Two entities of gestational trophoblastic disease with a common ultrasonographic appearance. ( 1656062 )
1991
42
Perforating invasive mole masquerading as an ovarian tumour--case report. ( 1839922 )
1991
43
Ultrasonic morphology of the uterus and ovaries after treatment of invasive mole and gestational choriocarcinoma. ( 2176560 )
1990
44
Clinical significance of hysterography in the diagnosis of choriocarcinoma and invasive mole. ( 2167821 )
1990
45
Doppler color flow mapping of an invasive mole. ( 2537784 )
1989
46
Lectin binding in tissues from hydatidiform mole, invasive mole and choriocarcinoma to concanavalin-A, wheat germ agglutinin and peanut agglutinin. ( 2560369 )
1989
47
Toxicity of vincristine overdose in a patient with invasive mole. ( 2559130 )
1989
48
Pregnancy outcomes after successful chemotherapy for choriocarcinoma and invasive mole: long-term follow-up. ( 3348314 )
1988
49
Choriocarcinoma and invasive mole. Clinicopathologic study of 65 autopsied cases. ( 2855050 )
1988
50
Immobilized Datura stramonium agglutinin column chromatography, a novel method to discriminate the urinary hCGs of patients with invasive mole and choriocarcinoma from those of normal pregnant women and patients with hydatidiform mole. ( 3130349 )
1988

Variations for Invasive Mole

Expression for Invasive Mole

Search GEO for disease gene expression data for Invasive Mole.

Pathways for Invasive Mole

GO Terms for Invasive Mole

Sources for Invasive Mole

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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