MCID: INV018
MIFTS: 22

Invasive Mole

Categories: Rare diseases, Reproductive diseases

Aliases & Classifications for Invasive Mole

MalaCards integrated aliases for Invasive Mole:

Name: Invasive Mole 58
Hydatidiform Mole, Invasive 70

Characteristics:

Orphanet epidemiological data:

58
invasive mole
Inheritance: Not applicable; Age of onset: Adult;

Classifications:

Orphanet: 58  
Rare gynaecological and obstetric diseases


External Ids:

ICD10 via Orphanet 33 D39.2
UMLS via Orphanet 71 C0008493
Orphanet 58 ORPHA99925
SNOMED-CT via HPO 68 314631008 351814001
UMLS 70 C0008493

Summaries for Invasive Mole

MalaCards based summary : Invasive Mole, also known as hydatidiform mole, invasive, is related to gestational trophoblastic neoplasm and recurrent hydatidiform mole. An important gene associated with Invasive Mole is CGB5 (Chorionic Gonadotropin Subunit Beta 5). Affiliated tissues include placenta, ovary and uterus, and related phenotypes are menometrorrhagia and high maternal serum chorionic gonadotropin

Related Diseases for Invasive Mole

Graphical network of the top 20 diseases related to Invasive Mole:



Diseases related to Invasive Mole

Symptoms & Phenotypes for Invasive Mole

Human phenotypes related to Invasive Mole:

58 31
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 menometrorrhagia 58 31 hallmark (90%) Very frequent (99-80%) HP:0400008
2 high maternal serum chorionic gonadotropin 58 31 hallmark (90%) Very frequent (99-80%) HP:0011433

Drugs & Therapeutics for Invasive Mole

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 The French National Reference Centre of Gestational Trophoblastic Disease Recruiting NCT02892877

Search NIH Clinical Center for Invasive Mole

Genetic Tests for Invasive Mole

Anatomical Context for Invasive Mole

MalaCards organs/tissues related to Invasive Mole:

40
Placenta, Ovary, Uterus, Tonsil, Pituitary

Publications for Invasive Mole

Articles related to Invasive Mole:

(show top 50) (show all 412)
# Title Authors PMID Year
1
Human chorionic gonadotropin tests. 54 61
19817556 2009
2
Human chorionic gonadotropin and associated molecules. 54 61
19099349 2009
3
Total laparoscopic hysterectomy in combination with dilation and evacuation of an 18-week-sized uterus with gestational trophoblastic neoplasia: a novel treatment approach. 61
33197418 2021
4
Gestational trophoblastic neoplasia: Novelties and challenges. 61
33685753 2021
5
Invasive mole with lung metastasis after an abdominal complete hydatidiform mole treatment. 61
33078868 2021
6
Conjoined twins in a spontaneous monochorionic triplet pregnancy: A case report and literature review. 61
33530268 2021
7
An invasive mole with pulmonary metastases in a 55-year-old postmenopausal Syrian woman: a case report and review of the literature. 61
33455574 2021
8
Distinct genomic profiles of gestational choriocarcinoma, a unique cancer of pregnant tissues. 61
33319857 2020
9
Clinical presentation and diagnosis of Gestational Trophoblastic Disease. 61
33422446 2020
10
Surgery including fertility-sparing treatment of GTD. 61
33127305 2020
11
Identification of a hydatidiform mole in twin pregnancy following assisted reproduction. 61
31833013 2020
12
The impact of previous cesarean section (C/S) on the risk for post-molar gestational trophoblastic neoplasia (GTN). 61
31954533 2020
13
Recurrent Thyroid Storm Caused by a Complete Hydatidiform Mole in a Perimenopausal Woman. 61
33425402 2020
14
Invasive mole in a perimenopausal woman with lung and vaginal metastases: A case report. 61
31893046 2019
15
Methotrexate-induced hemothorax in a woman with low-risk metastatic gestational trophoblastic disease. 61
31788529 2019
16
A case report of pelviscopic resection of invasive hydatidiform mole. 61
31593140 2019
17
Clinical characteristics and outcomes of extrauterine epithelioid trophoblastic tumors. 61
31312959 2019
18
Expression of p57 immunomarker in the classification and differential diagnosis of partial and complete hydatidiform moles. 61
31579240 2019
19
Gestational Trophoblastic Disease at Sultan Qaboos University Hospital: Prevalence, Risk Factors, Histological Features, Sonographic Findings, and Outcomes. 61
31110626 2019
20
RAPIDLY PROGRESSIVE AND SEVERE HIRSUTISM FROM HYPERREACTIO LUTEINALIS WITHIN A BACKGROUND OF POLYCYSTIC OVARY SYNDROME. 61
31967008 2019
21
Challenges in the diagnosis and treatment of gestational trophoblastic neoplasia worldwide. 61
30815369 2019
22
Incidence of gestational trophoblastic disease in South Korea: a longitudinal, population-based study. 61
30809458 2019
23
A Review on the Pathogenesis and Clinical Management of Placental Site Trophoblastic Tumors. 61
31850188 2019
24
Lectin histochemical analysis of uterine natural killer cells in normal, hydatidiform molar and invasive molar pregnancy. 61
30405783 2018
25
Sudden death due to an invasive mole in a young primigravida: Precipitous presentation masquerading the natural manner. 61
29969941 2018
26
Invasive molar pregnancy in rudimentary uterine horn. 61
29790311 2018
27
Predictive value of some hematological parameters for non-invasive and invasive mole pregnancies. 61
28093002 2018
28
Partial Invasive Mole with Bilateral Torsion of Theca Lutein Cysts. 61
29353908 2018
29
A metastatic invasive mole arising from iatrogenic uterus perforation. 61
29262807 2017
30
Bleeding from gestational trophoblastic neoplasia: embolotherapy efficacy and tumour response to chemotherapy. 61
28673447 2017
31
18F-FDG PET/CT Demonstrating Chorioadenoma Destruens After Evacuation of Complete Hydatidiform Mole. 61
28759528 2017
32
N-acetylglucosaminyltransferase IVa promotes invasion of choriocarcinoma. 61
28534963 2017
33
Salvage chemotherapy for gestational trophoblastic neoplasia: Utility or futility? 61
28473205 2017
34
Molecular and Immunohistochemical Characteristics of Complete Hydatidiform Moles. 61
28924538 2017
35
[Effects of prophylactic chemotherapy on outcomes and prognosis of patients older than 40 years with invasive mole]. 61
28647963 2017
36
Gestational Trophoblastic Disease: Clinical and Imaging Features. 61
28287945 2017
37
Laparoscopic Management of an Invasive Mole Perforating the Uterus. 61
27544879 2017
38
Unusual Presentation of Invasive Mole: A Case Report. 61
28377901 2017
39
[Clinical and radiological features of gestational trophoblastic tumors]. 61
29629014 2017
40
Gestational trophoblastic disease in Campinas, Brazil and persistency predictors. 61
29767872 2017
41
Giant invasive mole presenting as a cause of abdominopelvic mass in a perimenopausal woman: An unusual presentation of a rare pathology. 61
27896261 2016
42
The effect of molar pregnancies on platelet parameters. 61
27183899 2016
43
Perimenopausal invasive hyadatidiform mole treated by total abdominal hysterectomy followed by chemotherapy. 61
27651108 2016
44
Sonographic and Power Doppler Evaluation of an Invasive Mole Located in a Cesarean Scar Pregnancy. 61
27353688 2016
45
[¹⁸F]fluorodeoxyglucose positron emission tomography/computed tomography and trophoblastic disease: the gynecologist perspective. 61
26868372 2016
46
Gestational and Non-gestational Trophoblastic Disease. Guideline of the DGGG, OEGGG and SGGG (S2k Level, AWMF Registry No. 032/049, December 2015). 61
26941444 2016
47
Methotrexate and actinomycin D chemotherapy in a patient with porphyria: a case report. 61
26781485 2016
48
[Results of gestational trophoblastic neoplasia treatment in the Slovak Republic in the years from 1993 to 2012]. 61
26982057 2016
49
Clinical Characteristics of Gestational Trophoblastic Neoplasia: A 15-Year Hospital-Based Study. 61
26512786 2016
50
Spontaneous renal hemorrhage caused by invasive mole: a case report. 61
27352577 2016

Variations for Invasive Mole

Expression for Invasive Mole

Search GEO for disease gene expression data for Invasive Mole.

Pathways for Invasive Mole

GO Terms for Invasive Mole

Sources for Invasive Mole

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....