MCID: INV018
MIFTS: 24

Invasive Mole

Categories: Rare diseases, Reproductive diseases

Aliases & Classifications for Invasive Mole

MalaCards integrated aliases for Invasive Mole:

Name: Invasive Mole 60
Hydatidiform Mole, Invasive 74

Characteristics:

Orphanet epidemiological data:

60
invasive mole
Inheritance: Not applicable; Age of onset: Adult;

Classifications:



External Ids:

ICD10 via Orphanet 35 D39.2
UMLS via Orphanet 75 C0008493
Orphanet 60 ORPHA99925
SNOMED-CT via HPO 70 109546001 314631008 351814001
UMLS 74 C0008493

Summaries for Invasive Mole

MalaCards based summary : Invasive Mole, also known as hydatidiform mole, invasive, is related to gestational trophoblastic tumor and choriocarcinoma. An important gene associated with Invasive Mole is CGB5 (Chorionic Gonadotropin Subunit Beta 5). Affiliated tissues include uterus, lung and placenta, and related phenotypes are menometrorrhagia and high maternal serum chorionic gonadotropin

Wikipedia : 77 Invasive hydatidiform mole, also known as invasive mole and chorioadenoma destruens is a type of... more...

Related Diseases for Invasive Mole

Diseases related to Invasive Mole via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 14)
# Related Disease Score Top Affiliating Genes
1 gestational trophoblastic tumor 11.5
2 choriocarcinoma 10.6
3 hydatidiform mole, recurrent, 1 10.3
4 gestational trophoblastic neoplasm 10.3
5 gestational choriocarcinoma 10.1
6 ovarian hyperstimulation syndrome 10.0
7 hydronephrosis 10.0
8 partial hydatidiform mole 10.0
9 neutropenia 9.8
10 ectopic pregnancy 9.8
11 arteriovenous malformation 9.8
12 nephrotic syndrome 9.8
13 placental site trophoblastic tumor 9.8
14 paraplegia 9.8

Graphical network of the top 20 diseases related to Invasive Mole:



Diseases related to Invasive Mole

Symptoms & Phenotypes for Invasive Mole

Human phenotypes related to Invasive Mole:

60 33
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 menometrorrhagia 60 33 hallmark (90%) Very frequent (99-80%) HP:0400008
2 high maternal serum chorionic gonadotropin 60 33 hallmark (90%) Very frequent (99-80%) HP:0011433

Drugs & Therapeutics for Invasive Mole

Search Clinical Trials , NIH Clinical Center for Invasive Mole

Genetic Tests for Invasive Mole

Anatomical Context for Invasive Mole

MalaCards organs/tissues related to Invasive Mole:

42
Uterus, Lung, Placenta, Kidney, Ovary, Tonsil

Publications for Invasive Mole

Articles related to Invasive Mole:

(show top 50) (show all 76)
# Title Authors Year
1
Partial Invasive Mole with Bilateral Torsion of Theca Lutein Cysts. ( 29353908 )
2018
2
Sudden death due to an invasive mole in a young primigravida: Precipitous presentation masquerading the natural manner. ( 29969941 )
2018
3
A case of hereditary coproporphyria with posterior reversible encephalopathy and novel coproporphyrinogen oxidase gene mutation c.863T>G (p.Leu288Trp). ( 29660996 )
2018
4
Unusual Presentation of Invasive Mole: A Case Report. ( 28377901 )
2017
5
Predictive value of some hematological parameters for non-invasive and invasive mole pregnancies. ( 28093002 )
2017
6
A metastatic invasive mole arising from iatrogenic uterus perforation. ( 29262807 )
2017
7
Sonographic and Power Doppler Evaluation of an Invasive Mole Located in a Cesarean Scar Pregnancy. ( 27353688 )
2016
8
Spontaneous renal hemorrhage caused by invasive mole: a case report. ( 27352577 )
2016
9
Laparoscopic Management of an Invasive Mole Perforating the Uterus. ( 27544879 )
2016
10
Giant invasive mole presenting as a cause of abdominopelvic mass in a perimenopausal woman: An unusual presentation of a rare pathology. ( 27896261 )
2016
11
An invasive mole with bilateral kidney metastases: A case report. ( 26788142 )
2015
12
Invasive mole in a perimenopausal woman: a case report and systematic review. ( 26050078 )
2015
13
Invasive mole of the uterus- a rare case diagnosed by ultrasound: a case report. ( 24791851 )
2014
14
Laparoscopically diagnosed invasive mole presenting as acute hemoperitoneum. ( 25518774 )
2014
15
Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole. ( 25492410 )
2014
16
Unilateral hydronephrosis caused by invasive mole: a case report. ( 24260613 )
2013
17
Sonographic appearance of an advanced invasive mole and associated metastatic thrombus in the inferior vena cava. ( 22238139 )
2013
18
Partial hydatidiform mole progression into invasive mole with lung metastasis following in vitro fertilization. ( 22740971 )
2012
19
An invasive mole presenting with large arteriovenous malformation. ( 23372297 )
2012
20
Homonymous Quadrantanopsia as the First Manifestation of Cerebral Metastasis of Invasive Mole: a case report. ( 22531212 )
2012
21
Ovarian hyperstimulation syndrome in a spontaneous pregnancy with invasive mole: report of a case. ( 22355432 )
2011
22
Nephrotic syndrome associated with invasive mole: a case report. ( 20237056 )
2010
23
Four repetitive partial hydatidiform moles followed by malignant transformation to an invasive mole. ( 20846070 )
2010
24
Invasive mole--case report of massive uterine destruction. ( 19125711 )
2008
25
Invasive mole--case report of massive uterine destruction. ( 19145812 )
2008
26
Invasive mole: Indonesian perspective. ( 17939602 )
2007
27
A rare cause of hydronephrosis: invasive mole. ( 16891847 )
2006
28
Invasive mole in a postmenopausal woman. ( 16542659 )
2006
29
Metastatic invasive mole in the urinary bladder. ( 12928567 )
2002
30
'Metastatic invasive mole' causing paraplegia. ( 10921230 )
1999
31
Forty-five year's experience of the treatment of choriocarcinoma and invasive mole. ( 9833619 )
1998
32
Forty-five year's experience of the treatment of choriocarcinoma and invasive mole. ( 29645256 )
1998
33
Invasive mole presenting as a spinal extradural tumor: case report. ( 8747969 )
1996
34
Angiographic-guided embolization of metastatic invasive mole. ( 8641630 )
1996
35
Incidence of invasive mole and choriocarcinoma following partial hydatidiform mole. ( 8737309 )
1996
36
A clinical trial on diagnostic scoring system of choriocarcinoma and invasive mole in Vietnam. ( 8590362 )
1995
37
Usefulness of granulocyte colony-stimulating factor on neutropenia in patients of invasive mole and choriocarcinoma. ( 7531835 )
1995
38
Intrapartum uterine rupture in a primiparous patient previously treated for invasive mole. ( 8159371 )
1994
39
Perforation of the uterus by an invasive mole using color Doppler ultrasound: case report. ( 12796904 )
1993
40
Detection of an atypical invasive mole in an ectopic pregnancy by transvaginal color-flow Doppler. ( 8267086 )
1993
41
Immunohistochemical localization of inhibin-activin subunits in hydatidiform mole and invasive mole. ( 8395038 )
1993
42
Prophylactic effect of bestatin on the onset of invasive mole--clinical and fundamental studies. ( 1524955 )
1992
43
Invasive mole and placental site trophoblastic tumor. Two entities of gestational trophoblastic disease with a common ultrasonographic appearance. ( 1656062 )
1991
44
Perforating invasive mole masquerading as an ovarian tumour--case report. ( 1839922 )
1991
45
Ultrasonic morphology of the uterus and ovaries after treatment of invasive mole and gestational choriocarcinoma. ( 2176560 )
1990
46
Clinical significance of hysterography in the diagnosis of choriocarcinoma and invasive mole. ( 2167821 )
1990
47
Doppler color flow mapping of an invasive mole. ( 2537784 )
1989
48
Lectin binding in tissues from hydatidiform mole, invasive mole and choriocarcinoma to concanavalin-A, wheat germ agglutinin and peanut agglutinin. ( 2560369 )
1989
49
Toxicity of vincristine overdose in a patient with invasive mole. ( 2559130 )
1989
50
Pregnancy outcomes after successful chemotherapy for choriocarcinoma and invasive mole: long-term follow-up. ( 3348314 )
1988

Variations for Invasive Mole

Expression for Invasive Mole

Search GEO for disease gene expression data for Invasive Mole.

Pathways for Invasive Mole

GO Terms for Invasive Mole

Sources for Invasive Mole

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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