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MCID: IRD001
MIFTS: 43

Iridocyclitis

Categories: Eye diseases
Genes Tissues Related diseases Publications Pathways Drugs
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Aliases & Classifications for Iridocyclitis

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MalaCards integrated aliases for Iridocyclitis:

Name: Iridocyclitis 12 76 55 15 73
Primary Iridocyclitis 12 73

Classifications:

MalaCards categories:
Anatomical: Eye diseases
See all MalaCards categories (disease lists)
ICD10: 33


External Ids:

Disease Ontology 12 DOID:9383
ICD9CM 35 364.01 364.2
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Summaries for Iridocyclitis

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MalaCards based summary : Iridocyclitis, also known as primary iridocyclitis, is related to fuchs' heterochromic uveitis and chorioretinitis. An important gene associated with Iridocyclitis is DEK (DEK Proto-Oncogene), and among its related pathways/superpathways are NF-kappaB Signaling and Influenza A. The drugs Ganciclovir and Methotrexate have been mentioned in the context of this disorder. Affiliated tissues include eye, retina and endothelial.

Wikipedia : 76 Uveitis is the inflammation of the uvea, the pigmented layer that lies between the inner retina and the... more...

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Related Diseases for Iridocyclitis

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Diseases related to Iridocyclitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 126)
# Related Disease Score Top Affiliating Genes
1 fuchs' heterochromic uveitis 33.8 CYP11B1 MRAP
2 chorioretinitis 30.1 CD40LG MRAP
3 juvenile rheumatoid arthritis 30.0 DEK HLA-DPB1
4 glaucomatocyclitic crisis 29.7 HLA-B MRAP
5 spondylitis 29.3 CD40LG HLA-B
6 iritis 29.1 CD40LG HLA-B MRAP
7 spondyloarthropathy 1 28.8 CD40LG HLA-B MRAP
8 rubella 28.5 CD40LG HLA-B HLA-DPB1
9 lens-induced iridocyclitis 12.1
10 gonococcal iridocyclitis 11.9
11 infectious anterior uveitis 11.5
12 phacoanaphylactic uveitis 11.4
13 anterior uveitis 11.3
14 retinal vasculitis 11.0
15 uveitis 10.6
16 arthritis 10.4
17 idiopathic anterior uveitis 10.3
18 optic papillitis 10.3 CD40LG MRAP
19 acute retinal necrosis syndrome 10.3 CD40LG MRAP
20 diffuse infiltrative lymphocytosis syndrome 10.3 MRAP TNFRSF10B
21 urethritis 10.3 CD40LG MRAP
22 transient arthritis 10.3 CD40LG MRAP
23 cervix disease 10.3 CD40LG MRAP
24 vulvitis 10.3 CD40LG MRAP
25 acute salpingitis 10.3 CD40LG MRAP
26 urethral syndrome 10.3 CD40LG MRAP
27 coccidiosis 10.3 CD40LG MRAP
28 palindromic rheumatism 10.3 MRAP TNFRSF10B
29 rheumatoid arthritis 10.3
30 conjunctival disease 10.2 CD40LG MRAP
31 marginal zone b-cell lymphoma 10.2 CD40LG TNFAIP3
32 cataract 10.2
33 hypersensitivity reaction type iv disease 10.2 CD40LG MRAP
34 la crosse encephalitis 10.2 CD40LG TNFRSF10B
35 bone inflammation disease 10.1 CD40LG MRAP
36 herpes simplex 10.0
37 spondyloarthropathy 10.0 HLA-B MRAP
38 geographic tongue 10.0 HLA-B TNFRSF10B
39 vogt-koyanagi-harada disease 10.0
40 infectious posterior uveitis 10.0
41 idiopathic posterior uveitis 10.0
42 retinitis 10.0
43 indeterminate leprosy 9.9 CD40LG HLA-B
44 chikungunya 9.9
45 hypopyon 9.9
46 toxoplasmosis 9.9
47 echinococcosis 9.9 CD40LG HLA-B
48 conjunctivitis 9.8
49 psoriasis 9.8
50 ocular toxoplasmosis 9.8

Graphical network of the top 20 diseases related to Iridocyclitis:



Diseases related to Iridocyclitis
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Symptoms & Phenotypes for Iridocyclitis

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Drugs & Therapeutics for Iridocyclitis

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Drugs for Iridocyclitis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 112)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ganciclovir Approved, Investigational Phase 4,Not Applicable 82410-32-0 3454
2
Methotrexate Approved Phase 4,Not Applicable 1959-05-2, 59-05-2 126941
3
Adalimumab Approved Phase 4,Phase 3 331731-18-1 16219006
4
Ephedrine Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 299-42-3 9294
5
Pseudoephedrine Approved Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable 90-82-4 7028
6
Bimatoprost Approved, Investigational Phase 4 155206-00-1 5311027
7
Dinoprost Tromethamine Approved, Vet_approved Phase 4 38562-01-5 5282415
8
Certolizumab pegol Approved Phase 4,Phase 3 428863-50-7
9
leucovorin Approved, Nutraceutical Phase 4,Not Applicable 58-05-9 143 6006
10
Folic Acid Approved, Nutraceutical, Vet_approved Phase 4,Not Applicable 59-30-3 6037
11
Dinoprost Investigational Phase 4 551-11-1 5283078
12 Folic Acid Antagonists Phase 4,Not Applicable
13 Ganciclovir triphosphate Phase 4,Not Applicable
14 Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
15 Dermatologic Agents Phase 4,Phase 3,Not Applicable
16 Nucleic Acid Synthesis Inhibitors Phase 4,Not Applicable
17 Hormones Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
18 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
19 Peripheral Nervous System Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
20 Vitamin B Complex Phase 4,Not Applicable
21 Immunosuppressive Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
22 Anti-Infective Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
23 Anti-Inflammatory Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
24 Antirheumatic Agents Phase 4,Phase 3,Not Applicable
25 Antimetabolites Phase 4,Not Applicable
26 Antiviral Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
27 Autonomic Agents Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
28 Antimetabolites, Antineoplastic Phase 4,Not Applicable
29 beta-endorphin Phase 4,Not Applicable
30 Respiratory System Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
31 Adrenocorticotropic Hormone Phase 4,Not Applicable
32 Nasal Decongestants Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
33 Tetrahydrozoline Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
34 Ophthalmic Solutions Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
35 Oxytocics Phase 4
36 Vasoconstrictor Agents Phase 4,Phase 3,Phase 1,Phase 2,Not Applicable
37 Pharmaceutical Solutions Phase 4,Phase 3,Phase 2,Phase 1,Not Applicable
38 Antihypertensive Agents Phase 4
39 Anti-Infective Agents, Local Phase 4,Phase 3
40 Lubricant Eye Drops Phase 4
41 Melanocyte-Stimulating Hormones Phase 4,Not Applicable
42 Benzalkonium Compounds Phase 4,Phase 3
43 Folate Nutraceutical Phase 4,Not Applicable
44 Vitamin B9 Nutraceutical Phase 4,Not Applicable
45
Ranibizumab Approved Phase 2, Phase 3 347396-82-1 459903
46
Etanercept Approved, Investigational Phase 3,Not Applicable 185243-69-0
47
Prednisolone Approved, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 50-24-8 5755
48
Acyclovir Approved Phase 3 59277-89-3 2022
49
Methylprednisolone Approved, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 83-43-2 6741
50
Dexamethasone Approved, Investigational, Vet_approved Phase 3,Phase 2,Phase 1,Not Applicable 50-02-2 5743

Interventional clinical trials:

(show top 50) (show all 63)
# Name Status NCT ID Phase Drugs
1 Study of H.P. ACTHAR Subcutaneous Gelatin (Gel)(Highly Purified Gel Injection) in Uveitis Patients Completed NCT02764697 Phase 4 H.P. ACTHAR SUBCUTANEOUS GEL INJECTION
2 Prostaglandin F2-alpha Eye Drops in Thyroid Eye Disease (Bima Study) Completed NCT02059655 Phase 4 Bimatoprost;Eye drop solution
3 A Study Treating Participants With Early Axial Spondyloarthritis (axSpA) Taking an Intense Treatment Approach Versus Routine Treatment Completed NCT02897115 Phase 4
4 Topical 2% Ganciclovir Eye Drop for CMV Anterior Uveitis / Endotheliitis Recruiting NCT02943057 Phase 4 2% guttae ganciclovir
5 Open Label Study of Acthar SQ Gel Injection in Patients With Active Anterior Uveitis Recruiting NCT02769702 Phase 4 Acthar
6 A Study to Assess the Effects of Certolizumab Pegol on the Reduction of Anterior Uveitis (AU) Flares in Axial Spondyloarthritis Subjects With a Documented History of AU Active, not recruiting NCT03020992 Phase 4 Certolizumab Pegol
7 Methotrexate in the Treatment of Axial Spondyloarthritis Withdrawn NCT00298012 Phase 4 Methotrexate
8 Herpetic Eye Disease Study (HEDS) I Unknown status NCT00000138 Phase 3 Prednisolone Phosphate;Acyclovir
9 Double-dose Ranibizumab for Polypoidal Choroidal Vasculopathy Unknown status NCT02769169 Phase 2, Phase 3 Lucentis® (Raibizumab) double-dose;Lucentis® (Raibizumab) regular-dose
10 Safety and Efficacy of Difluprednate 0.05% for the Treatment of Anterior Uveitis Completed NCT01201798 Phase 3 Difluprednate 0.05% ophthalmic emulsion;Prednisolone acetate 1.0% ophthalmic suspension
11 A Multi-center Study to Assess the Efficacy and Safety of LX211 in Active Non-infectious Anterior Uveitis Completed NCT00404885 Phase 3 Placebo;LX211;LX211;LX211
12 Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis Completed NCT00406887 Phase 3 Difluprednate Ophthalmic Emulsion
13 Safety and Efficacy Study of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution to Treat Non-Infectious Anterior Segment Uveitis Completed NCT01505088 Phase 3 40 mg/mL Dexamethasone phosphate ophthalmic solution;Prednisolone Acetate (1%) Eyedrops;100 mM sodium citrate buffer solution;Placebo Eyedrops
14 Study of Difluprednate Ophthalmic Emulsion in the Treatment of Severe Uveitis Completed NCT00407056 Phase 3 Difluprednate Ophthalmic Emulsion
15 Herpetic Eye Disease Study (HEDS) II Completed NCT00000139 Phase 3 Acyclovir
16 Study of Difluprednate in the Treatment of Uveitis Completed NCT00501579 Phase 3 Difluprednate;Prednisolone Acetate
17 A Study of the Long-term Safety and Efficacy of Adalimumab in Subjects With Intermediate-, Posterior-, or Pan-uveitis Completed NCT01148225 Phase 3 adalimumab
18 CLARITY Extension Study Completed NCT00641537 Phase 3 Cladribine;Placebo;Cladribine;Cladribine;Placebo
19 Suprachoroidal Injection of CLS-TA in Subjects Non-infectious Uveitis Completed NCT03097315 Phase 3
20 Suprachoroidal Injection of CLS-TA in Subjects With Macular Edema Associated With Non-infectious Uveitis Completed NCT02595398 Phase 3 4mg CLS-TA Suprachoriodal Injection;Sham Procedure
21 A Phase 3 Study to Evaluate ADX-102 Ophthalmic Solution in Subjects With Non-infectious Anterior-uveitis. Recruiting NCT03131154 Phase 3 ADX-102 Ophthalmic Solution (0.5%);Vehicle of ADX-102 Ophthalmic Solution
22 Treatment Tapering in JIA With Inactive Disease Recruiting NCT02840175 Phase 3 etanercept;adalimumab;Abatacept;Tocilizumab
23 A Long Term Extension Study of Ixekizumab (LY2439821) in Participants With Axial Spondyloarthritis Recruiting NCT03129100 Phase 3 Ixekizumab;Placebo
24 A Study of Ixekizumab (LY2439821) in Participants With Nonradiographic Axial Spondyloarthritis Recruiting NCT02757352 Phase 3 Ixekizumab;Placebo
25 Safety and Efficacy of Iontophoretic Dexamethasone Phosphate Ophthalmic Solution in Non-Infectious Anterior Uveitis Active, not recruiting NCT02517619 Phase 3 Dexamethasone Phosphate Ophthalmic Solution;Prednisolone Acetate Ophthalmic (1%)
26 A Study of Ixekizumab (LY2439821) in TNF Inhibitor Experienced Participants With Radiographic Axial Spondyloarthritis Active, not recruiting NCT02696798 Phase 3 Ixekizumab;Placebo
27 A Study of Ixekizumab (LY2439821) in bDMARD-Naive Participants With Radiographic Axial Spondyloarthritis Active, not recruiting NCT02696785 Phase 3 Ixekizumab;Placebo;Adalimumab
28 Multicenter Study Evaluating Certolizumab Pegol Compared to Placebo in Subjects With axSpA Without X-ray Evidence of AS Active, not recruiting NCT02552212 Phase 3
29 Systemic and Topical Antivirals for Control of Cytomegalovirus Anterior Uveitis Not yet recruiting NCT03576898 Phase 2, Phase 3 Topical ganciclovir versus oral valganciclovir versus placebo
30 A Study of the Safety and Efficacy of a New Treatment for Non-Infectious Anterior Uveitis Terminated NCT00333996 Phase 2, Phase 3 Dexamethasone
31 Proof of Concept Study to Evaluate Safety and Efficacy of LME636 in the Treatment of Acute Anterior Uveitis Completed NCT02482129 Phase 2 LME636 60 mg/mL ophthalmic solution;Dexamethasone 0.1% ophthalmic solution;LME636 Vehicle
32 A Safety and Efficacy Study of NS2 in Patients With Anterior Uveitis Completed NCT02406209 Phase 2 NS2;Prednisolone acetate ophthalmic suspension (1%)
33 Safety and Efficacy Study of DSP-Visulex for the Treatment of Anterior Uveitis Completed NCT02309385 Phase 1, Phase 2 8% Dexamethasone Sodium Phosphate - Visulex;15% Dexamethasone Sodium Phosphate - Visulex;Prednisolone Acetate (1%) Eye Drops
34 Exploratory Study on Topical ESBA105 in Acute Anterior Uveitis Completed NCT00823173 Phase 2
35 Study of Difluprednate Ophthalmic Emulsion in the Treatment of Uveitis Completed NCT00405496 Phase 2 Difluprednate Ophthalmic Emulsion
36 Human Anti-Tac (Daclizumab) to Treat Juvenile Idiopathic Arthritis (JIA)-Associated Uveitis Completed NCT00130637 Phase 2 Daclizumab
37 Topical Interferon Gamma for Macular Edema Secondary to Uveitis Completed NCT01376362 Phase 1, Phase 2 Interferon Gamma-1b
38 Safety and Efficacy Study of Iontophoresis and Dexamethasone Phosphate to Treat Anterior Uveitis Completed NCT00694135 Phase 2 EGP-437 1.6 mA-min at 0.4 with EyeGate® II System;EGP-437 4.8 mA-min at 1.2 mA with EyeGate® II System;EGP-437 10.0 mA-min at 2.5 mA with EyeGate® II System;EGP-437 14.0 mA-min at 3.5 mA with EyeGate® II System
39 Suprachoroidal Injection of Triamcinolone Acetonide in Subjects With Macular Edema Following Non-Infectious Uveitis Completed NCT02255032 Phase 2 4 mg CLS-TA;0.8 mg CLS-TA
40 Safety and Efficacy of AIN457 in Noninfectious Uveitis Completed NCT00685399 Phase 2 AIN457;AIN 457;AIN457
41 A Phase I/IIa Study for the Treatment of Uveitis With Iontophoresis Withdrawn NCT00499551 Phase 1, Phase 2
42 Subconjunctival Sirolimus for the Treatment of Autoimmune Active Anterior Uveiti Completed NCT00876434 Phase 1 Sirolimus
43 Subconjunctival IVIg (Gamunex-C) Injection for Corneal Neovascularization and Inflammatory Conditions Withdrawn NCT02042027 Phase 1 Gamunex-C
44 Acute Anterior Uveitis: Psychic Burden and Pain Unknown status NCT01156285
45 Clinical Outcomes of Topical Ganciclovir Treatment in Cytomegalovirus Anterior Uveitis Unknown status NCT01486693
46 Quality of Life and Visual Function in Uveitis Patients Unknown status NCT00407316
47 Etanercept: Single Blind Control Study in Ocular Manifestations of Behcet's Disease Unknown status NCT00931957 Not Applicable Etanercept, Methotrexate, Prednisolone
48 Causes of Visual Loss in Retinal Disease Unknown status NCT01613963 Immunosuppressive Agents
49 PEMF: an Adjunct Therapy for Anterior Uveitis Completed NCT01154010 Not Applicable
50 Topical Administration of 0.15% Ganciclovir Gel for CMV Anterior Uveitis / Endotheliitis Completed NCT01647529 Not Applicable Ganciclovir

Search NIH Clinical Center for Iridocyclitis

Inferred drug relations via UMLS 73 / NDF-RT 51 :
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Genetic Tests for Iridocyclitis

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Anatomical Context for Iridocyclitis

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MalaCards organs/tissues related to Iridocyclitis:

41
Eye, Retina, Endothelial, Thyroid, Neutrophil, Liver, Testes
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Publications for Iridocyclitis

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Articles related to Iridocyclitis:

(show top 50) (show all 280)
# Title Authors Year
1
Fever of unknown origin, bilateral sensorineural hearing loss with canal paresis and uveitis with iridocyclitis and episcleritis: a case of Cogan's syndrome. ( 29703835 )
2018
2
Niemann-Pick Disease Type C Associated with Fuchs Heterochromic Iridocyclitis. ( 29387679 )
2017
3
Anti-dense Fine Speckled 70 Autoantibodies in Japanese Children with Dermatomyositis, Localized Scleroderma, and Idiopathic Arthritis with Iridocyclitis. ( 28461535 )
2017
4
Intraocular Lymphoma Masquerading as Recurrent Iridocyclitis: Findings Based on in vivo Confocal Microscopy. ( 29099641 )
2017
5
The unusual association of inverse retinitis pigmentosa and Fuchs' heterochromic iridocyclitis. ( 28127443 )
2017
6
Leprosy Presenting with Iridocyclitis: A Diagnostic Dilemma. ( 29090057 )
2017
7
Zika virus-related hypertensive iridocyclitis. ( 26840174 )
2016
8
Risk Factors for Glaucoma in a Cohort of Patients with Fuchs Heterochromic Iridocyclitis. ( 27494676 )
2016
9
Phacoemulsification Versus Manual Small Incision Cataract Surgery in Patients With Fuchs Heterochromic Iridocyclitis. ( 26939115 )
2016
10
Recurrent iridocyclitis due to cotton fiber in anterior chamber. ( 28242892 )
2016
11
Fuchs' Heterochromic Iridocyclitis in an Italian Tertiary Referral Centre: Epidemiology, Clinical Features, and Prognosis. ( 27781126 )
2016
12
Bilateral acute iris transillumination (BAIT) initially misdiagnosed as acute iridocyclitis. ( 25945534 )
2015
13
Polymorphisms in cytomegalovirus genotype in immunocompetent patients with corneal endotheliitis or iridocyclitis. ( 25963863 )
2015
14
Analysis on the psychological characteristics of patients with acute iridocyclitis. ( 26086022 )
2015
15
Acute granulomatous iridocyclitis in a child with tubulointerstitial nephritis and uveitis syndrome. ( 25861394 )
2015
16
Fuch's Heterochromic Iridocyclitis in Iran: Is the Disease Going to Fade Away? ( 26730326 )
2015
17
Syphilis iridocyclitis in a patient with type 1 diabetes. ( 27180731 )
2015
18
Small-incision cataract surgery in patients with Fuch's heterochromic iridocyclitis. ( 25680261 )
2014
19
Herniation of the retina in the central macula in an adult after iridocyclitis. ( 26011975 )
2014
20
Clinical, histopathological and immunohistochemical characterization of a novel equine ocular disorder: heterochromic iridocyclitis with secondary keratitis in adult horses. ( 25399915 )
2014
21
Associations of Fuchs heterochromic iridocyclitis in a South Indian patient population. ( 23514352 )
2013
22
Polymorphisms of TNFAIP3 Gene in a Chinese Han Population with Fuchs Heterochromic Iridocyclitis. ( 23463983 )
2013
23
Hypertensive iridocyclitis associated with delayed onset biopsy proven Cytomegalovirus retinitis. ( 23548320 )
2013
24
Surgical management of secondary glaucoma in Fuchs' heterochromic iridocyclitis. ( 23519886 )
2013
25
Implantation of iris-claw Artisan intraocular lens for aphakia in Fuchs' heterochromic iridocyclitis. ( 23571252 )
2013
26
Chikungunya virus iridocyclitis in Fuchs' heterochromic iridocyclitis. ( 22218256 )
2012
27
Frequency of iridocyclitis in patients with early psoriatic arthritis: a prospective, follow up study. ( 22898222 )
2012
28
Fuchs heterochromic iridocyclitis and the rubella virus. ( 21897135 )
2011
29
Adenoma of the nonpigmented ciliary epithelium presenting with recurrent iridocyclitis: unique expression of glial fibrillary acidic protein. ( 21088853 )
2011
30
Corneal astigmatism in unilateral Fuchs heterochromic iridocyclitis. ( 21595529 )
2011
31
Fuchs' heterochromic iridocyclitis associated with ocular toxocariasis. ( 21331701 )
2011
32
Bilateral acute depigmentation of the iris first misdiagnosed as acute iridocyclitis. ( 21633847 )
2011
33
Rubella virus as a possible etiological agent of Fuchs heterochromic iridocyclitis. ( 20585798 )
2010
34
Expression Profile of Intravitreous Cytokines, Chemokines and Growth Factors in Patients with Fuchs Heterochromic Iridocyclitis. ( 20737053 )
2010
35
Chikungunya virus iridocyclitis in Fuchs' heterochromic iridocyclitis. ( 20952847 )
2010
36
Confocal scan features of keratic precipitates in Fuchs heterochromic iridocyclitis. ( 19907293 )
2010
37
The possible role of systemic azithromycin for idiopathic iridocyclitis. ( 19891670 )
2010
38
Sarcoidosis presenting with massive splenomegaly in a child with a history of iridocyclitis and sensorineural deafness. ( 20615071 )
2010
39
Levocetirizine-induced iridocyclitis in a patient with allergic rhinitis. ( 20232781 )
2010
40
Retinal thickening in iridocyclitis. ( 19477710 )
2009
41
Fuchs heterochromic iridocyclitis--syndrome, disease, or both? ( 19782794 )
2009
42
Klebsiella pneumoniae endophthalmitis secondary to liver abscess presenting as acute iridocyclitis. ( 19772282 )
2009
43
Presumed Fuchs heterochromic iridocyclitis and Posner-Schlossman syndrome: comparison of cytomegalovirus-positive and -negative eyes. ( 19463548 )
2009
44
Presumed fuchs heterochromic iridocyclitis and Posner-Schlossman syndrome: comparison of cytomegalovirus-positive and negative eyes. ( 19027423 )
2008
45
Idiopathic no more: clues to the pathogenesis of Fuchs heterochromic iridocyclitis and glaucomatocyclitic crisis. ( 18435976 )
2008
46
Kinetics of aqueous flare, intraocular pressure and virus-DNA copies in a patient with cytomegalovirus iridocyclitis without retinitis. ( 17522780 )
2007
47
Epidemiologic relationship between fuchs heterochromic iridocyclitis and the United States rubella vaccination program. ( 17631266 )
2007
48
When should intraocular lenses be implanted in patients with juvenile idiopathic arthritis-associated iridocyclitis? ( 17057416 )
2006
49
Hypertensive iridocyclitis. ( 16782945 )
2006
50
Iridocyclitis associated with angle-supported phakic intraocular lenses. ( 16814060 )
2006
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Variations for Iridocyclitis

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Expression for Iridocyclitis

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Search GEO for disease gene expression data for Iridocyclitis.
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Pathways for Iridocyclitis

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Pathways related to Iridocyclitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1
NF-kappaB Signaling 4
12.06 CD40LG TNFAIP3 TNFRSF10B
2
Influenza A 37
Show member pathways
 11.95 HLA-B HLA-DPB1 TNFAIP3 TNFRSF10B
3
Epstein-Barr virus infection 37
11.74 HLA-B HLA-DPB1 TNFAIP3
4
Apoptosis and Autophagy 4
11.6 CD40LG TNFAIP3 TNFRSF10B
5
Cell adhesion molecules (CAMs) 37
10.96 CD40LG HLA-B HLA-DPB1
6
CD40/CD40L signaling 1
10.8 CD40LG TNFAIP3
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GO Terms for Iridocyclitis

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Cellular components related to Iridocyclitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 ER to Golgi transport vesicle membrane GO:0012507 9.16 HLA-B HLA-DPB1
2 integral component of lumenal side of endoplasmic reticulum membrane GO:0071556 8.96 HLA-B HLA-DPB1
3 cell surface GO:0009986 8.92 CD40LG HLA-B HLA-DPB1 TNFRSF10B

Biological processes related to Iridocyclitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 inflammatory response GO:0006954 9.58 CD40LG TNFAIP3 TNFRSF10B
2 T cell costimulation GO:0031295 9.37 CD40LG HLA-DPB1
3 interferon-gamma-mediated signaling pathway GO:0060333 9.32 HLA-B HLA-DPB1
4 positive regulation of T cell proliferation GO:0042102 9.26 CD40LG HLA-DPB1
5 antigen processing and presentation GO:0019882 9.16 HLA-B HLA-DPB1
6 immune response GO:0006955 9.1 CD40LG CYP11B1 HLA-B HLA-DPB1 TNFAIP3 TNFRSF10B
7 negative regulation of extrinsic apoptotic signaling pathway via death domain receptors GO:1902042 8.96 TNFAIP3 TNFRSF10B

Molecular functions related to Iridocyclitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 peptide antigen binding GO:0042605 8.62 HLA-B HLA-DPB1
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Sources for Iridocyclitis

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3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
The MalaCards human disease database index: 1-9 A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
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