MCID: ISC003
MIFTS: 27

Ischemic Fasciitis

Aliases & Classifications for Ischemic Fasciitis

MalaCards integrated aliases for Ischemic Fasciitis:

Name: Ischemic Fasciitis 12 15 72
Atypical Decubital Fibroplasia 12

External Ids:

Disease Ontology 12 DOID:9601
NCIt 50 C6483
UMLS 72 C1304514

Summaries for Ischemic Fasciitis

MalaCards based summary : Ischemic Fasciitis, also known as atypical decubital fibroplasia, is related to fasciitis and lipomatosis, multiple. An important gene associated with Ischemic Fasciitis is DES (Desmin), and among its related pathways/superpathways are Glioma and Mitotic G1-G1/S phases. Related phenotypes are muscle and neoplasm

Related Diseases for Ischemic Fasciitis

Diseases related to Ischemic Fasciitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 173)
# Related Disease Score Top Affiliating Genes
1 fasciitis 31.0 USP6 MUC1 DES ACTC1
2 lipomatosis, multiple 30.0 MDM2 DES CDK4
3 dedifferentiated liposarcoma 28.9 MDM2 DES CDKN2A CDK4 ACTC1
4 liposarcoma 28.6 MDM2 DES CDKN2A CDK4 CD34
5 angiolipoma 10.8 DES ACTC1
6 ovarian fibrothecoma 10.7 DES ACTC1
7 fibroblastic rheumatism 10.7 DES ACTC1
8 botryoid rhabdomyosarcoma 10.7 DES ACTC1
9 spindle cell thymoma 10.7 MUC1 DES
10 glomangioma 10.7 DES ACTC1
11 epithelioid leiomyosarcoma 10.7 DES ACTC1
12 benign metastasizing leiomyoma 10.7 DES ACTC1
13 malignant ectomesenchymoma 10.7 S100A1 DES
14 papillary tumor of the pineal region 10.6 S100A1 MUC1
15 biphasic synovial sarcoma 10.6 MUC1 DES
16 spindle cell rhabdomyosarcoma 10.6 MUC1 DES
17 mesenchymoma 10.6 MDM2 DES
18 pulmonary vein stenosis 10.6 DES ACTC1
19 non-langerhans-cell histiocytosis 10.6 DES ACTC1
20 adenofibroma 10.6 MUC1 ACTC1
21 spiradenoma 10.6 MUC1 ACTC1
22 syringoma 10.6 MUC1 DES
23 myxofibrosarcoma 10.5 MDM2 DES
24 desmoplastic small round cell tumor 10.5 MUC1 DES
25 proximal spinal muscular atrophy 10.5 MUC1 DES
26 congenital fibrosarcoma 10.5 DES ACTC1
27 cutaneous fibrous histiocytoma 10.5 DES ACTC1
28 cutaneous leiomyosarcoma 10.5 MUC1 DES ACTC1
29 syringocystadenoma papilliferum 10.5 MUC1 DES ACTC1
30 parachordoma 10.5 MUC1 DES ACTC1
31 ossifying fibromyxoid tumor 10.5 MUC1 DES ACTC1
32 perivascular epithelioid cell tumor 10.5 MUC1 DES ACTC1
33 rhabdoid tumor predisposition syndrome 1 10.5 MUC1 DES ACTC1
34 spindle cell carcinoma 10.5 MUC1 DES ACTC1
35 extraskeletal ewing sarcoma 10.5 MUC1 DES
36 kidney hemangiopericytoma 10.5 CD34 ACTC1
37 glomangiomyoma 10.5 CD34 ACTC1
38 carcinosarcoma 10.5 MUC1 DES ACTC1
39 giant cell tumor 10.5 MUC1 DES ACTC1
40 gallbladder sarcoma 10.5 DES CD34
41 mesenchymal chondrosarcoma 10.5 MUC1 DES
42 orbital granuloma 10.4 MUC1 CD34
43 cavernous hemangioma 10.4 S100A1 MUC1 DES
44 breast leiomyosarcoma 10.4 CD34 ACTC1
45 bizarre leiomyoma 10.4 CDKN2A ACTC1
46 malignant peritoneal mesothelioma 10.4 MUC1 CDKN2A
47 glomus tumor 10.4 DES ACTC1
48 ring chromosome 7 10.4 MDM2 CDK4
49 undifferentiated embryonal sarcoma of the liver 10.4 MDM2 CDK4
50 bile duct adenoma 10.4 MUC1 CDKN2A

Graphical network of the top 20 diseases related to Ischemic Fasciitis:



Diseases related to Ischemic Fasciitis

Symptoms & Phenotypes for Ischemic Fasciitis

MGI Mouse Phenotypes related to Ischemic Fasciitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 muscle MP:0005369 9.43 ACTC1 CDK4 CDKN2A DES MDM2 S100A1
2 neoplasm MP:0002006 9.02 CCND1 CD34 CDK4 CDKN2A MDM2

Drugs & Therapeutics for Ischemic Fasciitis

Search Clinical Trials , NIH Clinical Center for Ischemic Fasciitis

Genetic Tests for Ischemic Fasciitis

Anatomical Context for Ischemic Fasciitis

Publications for Ischemic Fasciitis

Articles related to Ischemic Fasciitis:

(show all 31)
# Title Authors PMID Year
1
Ischemic fasciitis in a debilitated older man. 38
31384211 2019
2
Ischemic Fasciitis Mimicking A Lipoma. 38
30789504 2019
3
Enlarging right thigh mass : Answer - Ischemic fasciitis. 38
30054695 2019
4
Ischemic Fasciitis of the Left Buttock in a 40-Year-Old Woman with Beta-Propeller Protein-Associated Neurodegeneration (BPAN). 38
30341275 2018
5
Novel t(1;2)(p36.1;q23) and t(7;19)(q32;q13.3) chromosomal translocations in ischemic fasciitis: expanding the spectrum of pseudosarcomatous lesions with clonal pathogenetic link. 38
29499721 2018
6
HIF-1α, MDM2, CDK4, and p16 expression in ischemic fasciitis, focusing on its ischemic condition. 38
28477272 2017
7
Ischemic fasciitis: enhanced diagnostic resolution through clinical, histopathologic and radiologic correlation in 17 cases. 38
27161342 2016
8
Management of recurrent ischemic fasciitis, a rare soft tissue pseudosarcoma. 38
24511502 2014
9
Decubital ischemic fasciitis. 38
23610895 2013
10
Abdominal wall ischemic fasciitis associated with a torso brace in a young girl. 38
23217950 2012
11
Spontaneous cutaneous cholesterol crystal embolism with focal clinical symptomatology: report of a case in an unusual location with secondary histological changes reminiscent of atypical decubital fibroplasia. 38
21946763 2011
12
Case report: MRI of decubital ischemic fasciitis. 38
21799593 2011
13
Ischemic fasciitis in an 85-year-old debilitated female. 38
21333928 2011
14
Decubital ischemic fasciitis presenting in an unusual location. 38
27307946 2011
15
Ischemic fasciitis with MRI findings. 38
20959275 2010
16
Ischemic fasciitis. 38
20860751 2010
17
[Ischemic fasciitis. A case report]. 38
19223110 2009
18
Ischemic fasciitis: analysis of 44 cases indicating an inconsistent association with immobility or debilitation. 38
18724246 2008
19
Pseudosarcomas of soft tissue. 38
18384209 2008
20
Decubital ischemic fasciitis: clinical, pathologic, and MRI features of pseudosarcoma. 38
17056926 2006
21
Pathologic quiz case: a 76-year-old debilitated woman with a right thigh mass. Ischemic fasciitis (atypical decubital fibroplasia). 38
15387683 2004
22
Ischemic fasciitis: an unusual vulvovaginal spindle cell lesion. 38
14668553 2004
23
Atypical decubital fibroplasia with unusual histology. 38
11878717 2001
24
Atypical decubital fibroplasia associated with bizarre parosteal osteochondromatous proliferation (Nora's reaction). 38
10093829 1999
25
Atypical decubital fibroplasia: a series of three cases. 38
9550313 1998
26
Atypical decubital fibroplasia in a young patient with melorheostosis. 38
9589481 1998
27
Ischemic fasciitis. Report of a case with fine needle aspiration findings. 38
9100807 1997
28
[Atypical decubitus fibroplasia: a recent entity. Apropos of a case of an adolescent girl]. 38
8672861 1996
29
[Atypical decubital fibroplasia (ischemic fasciitis)--a new pseudosarcomatous entity]. 38
7859318 1994
30
Ischemic fasciitis: a juxta-skeletal fibroblastic proliferation with a predilection for elderly patients. 38
8426859 1993
31
Atypical decubital fibroplasia. A distinctive fibroblastic pseudotumor occurring in debilitated patients. 38
1530110 1992

Variations for Ischemic Fasciitis

Expression for Ischemic Fasciitis

Search GEO for disease gene expression data for Ischemic Fasciitis.

Pathways for Ischemic Fasciitis

Pathways related to Ischemic Fasciitis according to GeneCards Suite gene sharing:

(show all 22)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.47 MDM2 CDKN2A CDK4 CCND1
2
Show member pathways
12.33 MDM2 CDKN2A CDK4 CCND1
3 12.27 MDM2 CDKN2A CDK4 CCND1
4 12.1 HLA-DRA CDKN2A CDK4 CCND1
5
Show member pathways
12.1 MDM2 CDKN2A CDK4 CCND1
6 12.06 MDM2 CDKN2A CDK4 CCND1
7
Show member pathways
12.03 MDM2 CDK4 CCND1
8
Show member pathways
12.02 CDKN2A CDK4 CCND1
9 11.97 MDM2 CDKN2A CDK4 CCND1
10 11.94 MDM2 CDK4 CCND1
11 11.93 MDM2 CDK4 CCND1
12 11.78 HLA-DRA CD68 CD34
13 11.76 MDM2 CDKN2A CCND1
14 11.76 MDM2 CDKN2A CDK4 CCND1
15 11.6 MDM2 CDK4 CCND1
16 11.3 MDM2 CDKN2A CDK4 CCND1
17 11.14 MDM2 CDK4 CCND1
18 11.01 CDK4 CCND1
19
Show member pathways
10.9 MDM2 CDKN2A
20 10.89 MDM2 CDKN2A
21 10.84 MDM2 CDKN2A CDK4
22 10.79 MDM2 CDKN2A CDK4 CCND1

GO Terms for Ischemic Fasciitis

Cellular components related to Ischemic Fasciitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 I band GO:0031674 8.62 S100A1 ACTC1

Biological processes related to Ischemic Fasciitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.73 MDM2 CDKN2A CD34 ACTC1
2 response to drug GO:0042493 9.62 MDM2 CDK4 CCND1 ACTC1
3 positive regulation of G2/M transition of mitotic cell cycle GO:0010971 9.46 CDK4 CCND1
4 G1/S transition of mitotic cell cycle GO:0000082 9.43 CDKN2A CDK4 CCND1
5 response to iron ion GO:0010039 9.4 MDM2 CCND1
6 response to magnesium ion GO:0032026 9.37 MDM2 CCND1
7 amyloid fibril formation GO:1990000 9.16 MDM2 CDKN2A
8 positive regulation of cell cycle GO:0045787 9.13 MDM2 CDK4 CCND1
9 negative regulation of cell cycle arrest GO:0071157 8.8 MDM2 CDK4 CCND1

Molecular functions related to Ischemic Fasciitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 SUMO transferase activity GO:0019789 8.62 MDM2 CDKN2A

Sources for Ischemic Fasciitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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