Aliases & Classifications for Ischemic Fasciitis

MalaCards integrated aliases for Ischemic Fasciitis:

Name: Ischemic Fasciitis 12 15 73
Atypical Decubital Fibroplasia 12

External Ids:

Disease Ontology 12 DOID:9601
NCIt 50 C6483
SNOMED-CT 68 403990005
UMLS 73 C1304514

Summaries for Ischemic Fasciitis

MalaCards based summary : Ischemic Fasciitis, also known as atypical decubital fibroplasia, is related to fasciitis and ovarian fibrothecoma. An important gene associated with Ischemic Fasciitis is DES (Desmin), and among its related pathways/superpathways are Endometrial cancer and Pathways in cancer. Related phenotypes are cardiovascular system and cellular

Related Diseases for Ischemic Fasciitis

Diseases related to Ischemic Fasciitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 173)
# Related Disease Score Top Affiliating Genes
1 fasciitis 30.7 ACTC1 DES MUC1 USP6
2 ovarian fibrothecoma 10.9 ACTC1 DES
3 fibroblastic rheumatism 10.9 ACTC1 DES
4 spindle cell thymoma 10.9 DES MUC1
5 angiolipoma 10.9 ACTC1 DES
6 botryoid rhabdomyosarcoma 10.8 ACTC1 DES
7 malignant ectomesenchymoma 10.8 DES S100A1
8 epithelioid leiomyosarcoma 10.8 ACTC1 DES
9 spindle cell rhabdomyosarcoma 10.8 DES MUC1
10 biphasic synovial sarcoma 10.8 DES MUC1
11 ovarian small cell carcinoma 10.8 DES MUC1
12 benign metastasizing leiomyoma 10.8 ACTC1 DES
13 papillary tumor of the pineal region 10.8 MUC1 S100A1
14 syringoma 10.8 DES MUC1
15 congenital fibrosarcoma 10.8 ACTC1 DES
16 pulmonary vein stenosis 10.8 ACTC1 DES
17 adenofibroma 10.8 ACTC1 MUC1
18 cystic nephroma 10.7 ACTC1 DES
19 desmoplastic small round cell tumor 10.7 DES MUC1
20 proximal spinal muscular atrophy 10.7 DES MUC1
21 mesenchymoma 10.7 DES MDM2
22 mesenchymal chondrosarcoma 10.7 DES MUC1
23 extraskeletal ewing sarcoma 10.7 DES MUC1
24 cutaneous fibrous histiocytoma 10.7 ACTC1 DES
25 glomus tumor 10.6 ACTC1 DES
26 non-langerhans-cell histiocytosis 10.6 ACTC1 DES
27 cutaneous leiomyosarcoma 10.6 ACTC1 DES MUC1
28 parachordoma 10.6 ACTC1 DES MUC1
29 ossifying fibromyxoid tumor 10.6 ACTC1 DES MUC1
30 gallbladder sarcoma 10.6 CD34 DES
31 syringocystadenoma papilliferum 10.6 ACTC1 DES MUC1
32 perivascular epithelioid cell tumor 10.6 ACTC1 DES MUC1
33 orbital granuloma 10.6 CD34 MUC1
34 glomangiomyoma 10.6 ACTC1 CD34
35 rhabdoid cancer 10.6 ACTC1 DES MUC1
36 malignant peritoneal mesothelioma 10.6 CDKN2A MUC1
37 spindle cell carcinoma 10.6 ACTC1 DES MUC1
38 anaplastic ependymoma 10.5 MDM2 MUC1
39 bizarre leiomyoma 10.5 ACTC1 CDKN2A
40 mucinous bronchioloalveolar adenocarcinoma 10.5 CDKN2A MUC1
41 ring chromosome 7 10.5 CDK4 MDM2
42 chondroid chordoma 10.5 MUC1 S100A1
43 endometrial mucinous adenocarcinoma 10.5 CDKN2A MUC1
44 pseudosarcomatous fibromatosis 10.5 ACTC1 DES USP6
45 undifferentiated embryonal sarcoma of the liver 10.5 CDK4 MDM2
46 chickenpox 10.5 ACTC1 MUC1
47 cholangiolocellular carcinoma 10.5 CDKN2A MUC1
48 sarcomatoid mesothelioma 10.5 CDKN2A MUC1
49 bone osteosarcoma 10.5 CDK4 MDM2
50 malignant iris melanoma 10.4 CCND1 S100A1

Graphical network of the top 20 diseases related to Ischemic Fasciitis:



Diseases related to Ischemic Fasciitis

Symptoms & Phenotypes for Ischemic Fasciitis

MGI Mouse Phenotypes related to Ischemic Fasciitis:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cardiovascular system MP:0005385 9.8 CCND1 CDK4 CDKN2A DES MDM2 S100A1
2 cellular MP:0005384 9.76 CCND1 CD34 CDK4 CDKN2A DES MDM2
3 muscle MP:0005369 9.43 CDK4 CDKN2A DES MDM2 S100A1 ACTC1
4 neoplasm MP:0002006 9.02 CCND1 CD34 CDK4 CDKN2A MDM2

Drugs & Therapeutics for Ischemic Fasciitis

Search Clinical Trials , NIH Clinical Center for Ischemic Fasciitis

Genetic Tests for Ischemic Fasciitis

Anatomical Context for Ischemic Fasciitis

Publications for Ischemic Fasciitis

Articles related to Ischemic Fasciitis:

(show all 18)
# Title Authors Year
1
Novel t(1;2)(p36.1;q23) and t(7;19)(q32;q13.3) chromosomal translocations in ischemic fasciitis: expanding the spectrum of pseudosarcomatous lesions with clonal pathogenetic link. ( 29499721 )
2018
2
HIF-1I+, MDM2, CDK4, and p16 expression in ischemic fasciitis, focusing on its ischemic condition. ( 28477272 )
2017
3
Ischemic fasciitis: enhanced diagnostic resolution through clinical, histopathologic, and radiologic correlation in 17 cases. ( 27161342 )
2016
4
Management of recurrent ischemic fasciitis, a rare soft tissue pseudosarcoma. ( 24511502 )
2014
5
Decubital ischemic fasciitis. ( 23610895 )
2013
6
Abdominal wall ischemic fasciitis associated with a torso brace in a young girl. ( 23217950 )
2012
7
Ischemic fasciitis in an 85-year-old debilitated female. ( 21333928 )
2011
8
Case report: MRI of decubital ischemic fasciitis. ( 21799593 )
2011
9
Decubital ischemic fasciitis presenting in an unusual location. ( 27307946 )
2011
10
Ischemic fasciitis with MRI findings. ( 20959275 )
2010
11
Ischemic fasciitis. ( 20860751 )
2010
12
Ischemic fasciitis: analysis of 44 cases indicating an inconsistent association with immobility or debilitation. ( 18724246 )
2008
13
Decubital ischemic fasciitis: clinical, pathologic, and MRI features of pseudosarcoma. ( 17056926 )
2006
14
Pathologic quiz case: a 76-year-old debilitated woman with a right thigh mass. Ischemic fasciitis (atypical decubital fibroplasia). ( 15387683 )
2004
15
Ischemic fasciitis: an unusual vulvovaginal spindle cell lesion. ( 14668553 )
2004
16
Ischemic fasciitis. Report of a case with fine needle aspiration findings. ( 9100807 )
1997
17
[Atypical decubital fibroplasia (ischemic fasciitis)--a new pseudosarcomatous entity]. ( 7859318 )
1994
18
Ischemic fasciitis: a juxta-skeletal fibroblastic proliferation with a predilection for elderly patients. ( 8426859 )
1993

Variations for Ischemic Fasciitis

Expression for Ischemic Fasciitis

Search GEO for disease gene expression data for Ischemic Fasciitis.

Pathways for Ischemic Fasciitis

Pathways related to Ischemic Fasciitis according to GeneCards Suite gene sharing:

(show all 24)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.66 CCND1 CDK4 CDKN2A MDM2
2 12.62 CCND1 CDK4 CDKN2A MDM2
3
Show member pathways
12.55 CCND1 CDK4 CDKN2A MDM2
4
Show member pathways
12.33 CCND1 CDK4 CDKN2A MDM2
5 12.25 CCND1 CDK4 CDKN2A MDM2
6 12.16 CCND1 CDK4 CDKN2A HLA-DRA
7
Show member pathways
12.1 CCND1 CDK4 CDKN2A MDM2
8
Show member pathways
12.06 CCND1 CDK4 MDM2
9 12.06 CCND1 CDK4 CDKN2A MDM2
10
Show member pathways
12.01 CCND1 CDK4 CDKN2A
11 11.97 CCND1 CDK4 CDKN2A MDM2
12 11.91 CCND1 CDK4 MDM2
13 11.78 CD34 CD68 HLA-DRA
14 11.76 CCND1 CDKN2A MDM2
15 11.76 CCND1 CDK4 CDKN2A MDM2
16 11.62 CCND1 CDK4 MDM2
17 11.3 CCND1 CDK4 CDKN2A MDM2
18 11.14 CCND1 CDK4 MDM2
19 11.12 CCND1 CDK4
20 11 CCND1 CDK4
21 10.91 CDKN2A MDM2
22
Show member pathways
10.9 CDKN2A MDM2
23 10.84 CDK4 CDKN2A MDM2
24 10.79 CCND1 CDK4 CDKN2A MDM2

GO Terms for Ischemic Fasciitis

Cellular components related to Ischemic Fasciitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cytoplasm GO:0005737 9.65 ACTC1 CCND1 CD34 CDK4 CDKN2A DES
2 I band GO:0031674 9.16 ACTC1 S100A1
3 cyclin-dependent protein kinase holoenzyme complex GO:0000307 8.62 CCND1 CDK4

Biological processes related to Ischemic Fasciitis according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 positive regulation of gene expression GO:0010628 9.76 ACTC1 CD34 CDKN2A MDM2
2 response to drug GO:0042493 9.67 ACTC1 CCND1 CDK4 MDM2
3 G1/S transition of mitotic cell cycle GO:0000082 9.58 CCND1 CDK4 CDKN2A
4 positive regulation of G2/M transition of mitotic cell cycle GO:0010971 9.49 CCND1 CDK4
5 response to iron ion GO:0010039 9.48 CCND1 MDM2
6 response to magnesium ion GO:0032026 9.43 CCND1 MDM2
7 positive regulation of cell cycle GO:0045787 9.33 CCND1 CDK4 MDM2
8 amyloid fibril formation GO:1990000 9.32 CDKN2A MDM2
9 negative regulation of cyclin-dependent protein serine/threonine kinase activity involved in G1/S transition of mitotic cell cycle GO:0031658 9.26 CDK4 CDKN2A
10 cellular response to organic substance GO:0071310 9.13 CCND1 CD68 MDM2
11 negative regulation of cell cycle arrest GO:0071157 8.8 CCND1 CDK4 MDM2

Molecular functions related to Ischemic Fasciitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cyclin-dependent protein serine/threonine kinase regulator activity GO:0016538 8.96 CCND1 CDK4
2 SUMO transferase activity GO:0019789 8.62 CDKN2A MDM2

Sources for Ischemic Fasciitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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