Aliases & Classifications for Ischemic Retinopathy

MalaCards integrated aliases for Ischemic Retinopathy:

Name: Ischemic Retinopathy 55

Summaries for Ischemic Retinopathy

MalaCards based summary : Ischemic Retinopathy is related to hypoxia and megaloblastic anemia. An important gene associated with Ischemic Retinopathy is SEMA3E (Semaphorin 3E), and among its related pathways/superpathways is Semaphorin interactions. Affiliated tissues include bone, endothelial and bone marrow.

Related Diseases for Ischemic Retinopathy

Graphical network of the top 20 diseases related to Ischemic Retinopathy:



Diseases related to Ischemic Retinopathy

Symptoms & Phenotypes for Ischemic Retinopathy

Drugs & Therapeutics for Ischemic Retinopathy

Search Clinical Trials , NIH Clinical Center for Ischemic Retinopathy

Genetic Tests for Ischemic Retinopathy

Anatomical Context for Ischemic Retinopathy

MalaCards organs/tissues related to Ischemic Retinopathy:

41
Bone, Endothelial, Bone Marrow, Myeloid, Retina, Ovary

Publications for Ischemic Retinopathy

Articles related to Ischemic Retinopathy:

(show top 50) (show all 84)
# Title Authors Year
1
High protein S activity due to C4b-binding protein deficiency in a 34-year-old Surinamese female with ischemic retinopathy. ( 29744091 )
2018
2
Nogo-A inhibits vascular regeneration in ischemic retinopathy. ( 30051920 )
2018
3
Deletion of p75NTR prevents vaso-obliteration and retinal neovascularization via activation of Trk- A receptor in ischemic retinopathy model. ( 30131506 )
2018
4
NCK-dependent pericyte migration promotes pathological neovascularization in ischemic retinopathy. ( 30150707 )
2018
5
Inhibition or deletion of 11I^-HSD1 does not increase angiogenesis in ischemic retinopathy. ( 28089372 )
2017
6
Impact of minocycline on vascularization and visual function in an immature mouse model of ischemic retinopathy. ( 28790417 )
2017
7
Interplay between CCN1 and Wnt5a in endothelial cells and pericytes determines the angiogenic outcome in a model of ischemic retinopathy. ( 28469167 )
2017
8
An apelin receptor antagonist prevents pathological retinal angiogenesis with ischemic retinopathy in mice. ( 29118394 )
2017
9
MicroRNA-126 Reduces Blood-Retina Barrier Breakdown via the Regulation of VCAM-1 and BCL2L11 in Ischemic Retinopathy. ( 28076855 )
2017
10
Silencing of galectin-1 inhibits retinal neovascularization and ameliorates retinal hypoxia in a murine model of oxygen-induced ischemic retinopathy. ( 28257831 )
2017
11
Evaluation of Nonperfused Retinal Vessels in Ischemic Retinopathy. ( 27661854 )
2016
12
Global metabolomics reveals metabolic dysregulation in ischemic retinopathy. ( 26617478 )
2016
13
Ischemic retinopathy associated with Crohn's disease. ( 27524921 )
2016
14
Intractable Intradialytic Hypotension with Ischemic Retinopathy. ( 27915344 )
2016
15
Treatment with polyamine oxidase inhibitor reduces microglial activation and limits vascular injury in ischemic retinopathy. ( 27239699 )
2016
16
Lack of R-Ras Leads to Increased Vascular Permeability in Ischemic Retinopathy. ( 27654416 )
2016
17
Gemigliptin, a dipeptidyl peptidase-4 inhibitor, inhibits retinal pericyte injury in db/db mice and retinal neovascularization in mice with ischemic retinopathy. ( 26391252 )
2015
18
Epac2-deficiency leads to more severe retinal swelling, glial reactivity and oxidative stress in transient middle cerebral artery occlusion induced ischemic retinopathy. ( 25985753 )
2015
19
A platform of integrative studies from in vitro to in vivo experiments: towards drug development for ischemic retinopathy. ( 25661384 )
2015
20
Severe ischemic retinopathy in a patient with systemic lupus erythematosus without antiphospholipid syndrome: A case report. ( 25892939 )
2015
21
ISCHEMIC RETINOPATHY IN NEUROFIBROMATOSIS TYPE 1. ( 26252734 )
2015
22
Candesartan stimulates reparative angiogenesis in ischemic retinopathy model: role of hemeoxygenase-1 (HO-1). ( 25420481 )
2015
23
S100A4 gene silencing in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via down-regulation of CREB expression. ( 26358273 )
2015
24
Activation of the Endothelin System Mediates Pathological Angiogenesis during Ischemic Retinopathy. ( 25203536 )
2014
25
Proliferative ischemic retinopathy after arteriovenous malformation embolization in a child with hereditary hemorrhagic telangiectasia. ( 25372443 )
2014
26
Ischemic retinopathy and neovascular proliferation secondary to severe head injury. ( 25143848 )
2014
27
Angiopoietin-1 guides directional angiogenesis through integrin I+vI^5 signaling for recovery of ischemic retinopathy. ( 24048525 )
2013
28
Microglia and interleukin-1I^ in ischemic retinopathy elicit microvascular degeneration through neuronal semaphorin-3A. ( 23766263 )
2013
29
Neuronal sirtuin1 mediates retinal vascular regeneration in oxygen-induced ischemic retinopathy. ( 23912262 )
2013
30
NADPH Oxidase, NOX1, Mediates Vascular Injury in Ischemic Retinopathy. ( 24053718 )
2013
31
Vitreous haemorrhage and ischemic retinopathy in a patient with CADASIL. ( 23064698 )
2013
32
Targeting Neovascularization in Ischemic Retinopathy: Recent Advances. ( 25598837 )
2013
33
Peripheral ischemic retinopathy in Adams-Oliver syndrome. ( 22893088 )
2012
34
Endogenous erythropoietin protects neuroretinal function in ischemic retinopathy. ( 22342523 )
2012
35
Zinc transporter 8 (ZnT8) expression is reduced by ischemic insults: a potential therapeutic target to prevent ischemic retinopathy. ( 23209723 )
2012
36
Hypoxia-induced oxidative stress in ischemic retinopathy. ( 23125893 )
2012
37
Macrophage metalloelastase (MMP-12) deficiency mitigates retinal inflammation and pathological angiogenesis in ischemic retinopathy. ( 23285156 )
2012
38
Overexpression of 15-lipoxygenase-1 in oxygen-induced ischemic retinopathy inhibits retinal neovascularization via downregulation of vascular endothelial growth factor-A expression. ( 23233787 )
2012
39
Sema3E-PlexinD1 signaling selectively suppresses disoriented angiogenesis in ischemic retinopathy in mice. ( 21505259 )
2011
40
Reduced retinal neovascularization, vascular permeability, and apoptosis in ischemic retinopathy in the absence of prolyl hydroxylase-1 due to the prevention of hyperoxia-induced vascular obliteration. ( 21873682 )
2011
41
Calpain inhibitors reduce retinal hypoxia in ischemic retinopathy by improving neovascular architecture and functional perfusion. ( 20804843 )
2011
42
Increased expression and activity of 12-lipoxygenase in oxygen-induced ischemic retinopathy and proliferative diabetic retinopathy: implications in retinal neovascularization. ( 21228311 )
2011
43
Hyperoxia therapy of pre-proliferative ischemic retinopathy in a mouse model. ( 21705685 )
2011
44
Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy. ( 22355595 )
2011
45
The matricellular protein cysteine-rich protein 61 (CCN1/Cyr61) enhances physiological adaptation of retinal vessels and reduces pathological neovascularization associated with ischemic retinopathy. ( 21212276 )
2011
46
Reduced nitro-oxidative stress and neural cell death suggests a protective role for microglial cells in TNFalpha-/- mice in ischemic retinopathy. ( 20107169 )
2010
47
Reversal of ischemic retinopathy following balloon angioplasty of a stenotic ophthalmic artery. ( 20418775 )
2010
48
Outgrowth endothelial cells: characterization and their potential for reversing ischemic retinopathy. ( 20554606 )
2010
49
Early intervention of tyrosine nitration prevents vaso-obliteration and neovascularization in ischemic retinopathy. ( 19815813 )
2010
50
Moderate GSK-3I^ inhibition improves neovascular architecture, reduces vascular leakage, and reduces retinal hypoxia in a model of ischemic retinopathy. ( 20809259 )
2010

Variations for Ischemic Retinopathy

Expression for Ischemic Retinopathy

Search GEO for disease gene expression data for Ischemic Retinopathy.

Pathways for Ischemic Retinopathy

GO Terms for Ischemic Retinopathy

Cellular components related to Ischemic Retinopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 8.62 PLXND1 SEMA3E

Biological processes related to Ischemic Retinopathy according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 multicellular organism development GO:0007275 9.26 PLXND1 SEMA3E
2 regulation of cell shape GO:0008360 9.16 PLXND1 SEMA3E
3 semaphorin-plexin signaling pathway GO:0071526 8.96 PLXND1 SEMA3E
4 branching involved in blood vessel morphogenesis GO:0001569 8.62 PLXND1 SEMA3E

Sources for Ischemic Retinopathy

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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