Isolated Duane Retraction Syndrome disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: ISL019 MIFTS: 23	Isolated Duane Retraction Syndrome Categories: Eye diseases
Tissues Related diseases Publications Symptoms & Phenotypes Expand all tables

Sources

Aliases & Classifications for Isolated Duane Retraction Syndrome

MalaCards integrated aliases for Isolated Duane Retraction Syndrome:

Name: Isolated Duane Retraction Syndrome ²⁵

Duane Retraction Syndrome ²⁵ ⁷²

Co-Contractive Retraction Syndrome ²⁵

Stilling-Turk-Duane Syndrome ²⁵

Ocular Retraction Syndrome ²⁵

Duane Anomaly, Isolated ²⁵

Duane's Syndrome ²⁵

Duane Syndrome ²⁵

Classifications:

MalaCards categories:
Anatomical: Eye diseases

See all MalaCards categories (disease lists)

External Ids:

UMLS ⁷² C0013261

Sources

Summaries for Isolated Duane Retraction Syndrome

Genetics Home Reference : ²⁵ Isolated Duane retraction syndrome is a disorder of eye movement. This condition prevents outward movement of the eye (toward the ear), and in some cases may also limit inward eye movement (toward the nose). As the eye moves inward, the eyelids partially close and the eyeball pulls back (retracts) into its socket. Most commonly, only one eye is affected. About 10 percent of people with isolated Duane retraction syndrome develop amblyopia ("lazy eye"), a condition that causes vision loss in the affected eye. About 70 percent of all cases of Duane retraction syndrome are isolated, which means they occur without other signs and symptoms. Duane retraction syndrome can also occur as part of syndromes that affect other areas of the body. For example, Duane-radial ray syndrome is characterized by this eye disorder in conjunction with abnormalities of bones in the arms and hands. Researchers have identified three forms of isolated Duane retraction syndrome, designated types I, II, and III. The types vary in which eye movements are most severely restricted (inward, outward, or both). All three types are characterized by retraction of the eyeball as the eye moves inward.

MalaCards based summary : Isolated Duane Retraction Syndrome, also known as duane retraction syndrome, is related to duane syndrome type 1 and duane syndrome type 3, and has symptoms including ophthalmoparesis and ophthalmoplegia. Affiliated tissues include eye, bone and brain.

Sources

Related Diseases for Isolated Duane Retraction Syndrome

Diseases related to Isolated Duane Retraction Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 161)

#	Related Disease	Score
1	duane syndrome type 1	12.7
2	duane syndrome type 3	12.6
3	duane syndrome type 2	12.5
4	duane retraction syndrome 1	12.4
5	duane retraction syndrome	11.8
6	duane-radial ray syndrome	11.7
7	wildervanck syndrome	11.5
8	monocular esotropia	10.6
9	esotropia	10.6
10	strabismus	10.6
11	mechanical strabismus	10.6
12	alternating exotropia	10.4
13	exotropia	10.4
14	ptosis	10.2
15	cataract	10.2
16	retinitis pigmentosa	10.2
17	sensorineural hearing loss	10.2
18	neuroretinitis	10.2
19	retinitis	10.2
20	torticollis	10.2
21	suppression amblyopia	10.2
22	amblyopia	10.2
23	abducens nerve disease	10.2
24	branchiootic syndrome 1	10.1
25	meningioma, radiation-induced	10.0
26	meningioma, familial	10.0
27	spinal meningioma	10.0
28	secretory meningioma	10.0
29	lymphoplasmacyte-rich meningioma	10.0
30	achondroplasia	10.0
31	autoimmune disease	10.0
32	cleft palate, isolated	10.0
33	solitary median maxillary central incisor	10.0
34	marfan syndrome	10.0
35	chromosome 9p deletion syndrome	10.0
36	dowling-degos disease 1	10.0
37	neural tube defects	10.0
38	c syndrome	10.0
39	charge syndrome	10.0
40	muscular dystrophy, duchenne type	10.0
41	retinitis pigmentosa-deafness syndrome	10.0
42	astigmatism	10.0
43	polydactyly	10.0
44	tukel syndrome	10.0
45	chromosome 16p13.3 deletion syndrome, proximal	10.0
46	alacrima, achalasia, and mental retardation syndrome	10.0
47	usher syndrome	10.0
48	usher syndrome type 2	10.0
49	cysticercosis	10.0
50	klippel-feil syndrome	10.0

Graphical network of the top 20 diseases related to Isolated Duane Retraction Syndrome:

Sources

Symptoms & Phenotypes for Isolated Duane Retraction Syndrome

UMLS symptoms related to Isolated Duane Retraction Syndrome:

ophthalmoparesis, ophthalmoplegia

Sources

Drugs & Therapeutics for Isolated Duane Retraction Syndrome

Interventional clinical trials:

#	Name	Status	NCT ID	Phase	Drugs
1	Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies	Recruiting	NCT03059420

Search NIH Clinical Center for Isolated Duane Retraction Syndrome

Sources

Genetic Tests for Isolated Duane Retraction Syndrome

Sources

Anatomical Context for Isolated Duane Retraction Syndrome

MalaCards organs/tissues related to Isolated Duane Retraction Syndrome:

⁴¹

Eye, Bone, Brain, Colon, Heart, Skin, Pituitary

Sources

Publications for Isolated Duane Retraction Syndrome

Articles related to Isolated Duane Retraction Syndrome:

(show top 50) (show all 186)

#	Title	Authors	PMID	Year
1	A modified technique for attaching the lateral rectus muscle to the orbital periosteum through a skin incision over the lateral orbital rim. ³⁸	Nagasubramanian V...Dandapani R	31103564	2019
2	Diffusion Tensor Imaging of the Lateral Rectus Muscle in Duane Retraction Syndrome. ³⁸	Abdel Razek AAK...Kasem MA	31082973	2019
3	Diffusion Tensor Imaging of the Lateral Rectus Muscle in Duane Retraction Syndrome. ³⁸	Abdel Razek AAK...Kasem MA	31082953	2019
4	Binocular Function in Subjects with Orthotropic Duane Retraction Syndrome. ³⁸	Marella BL...Kekunnaya R	31034344	2019
5	Absent cochlear and abducens nerves in a patient with Duane retraction syndrome. ³⁸	Yang HK...Hwang JM	30377846	2019
6	Botulinum toxin-A injection in esotropic Duane syndrome patients up to 2 years of age. ³⁸	Sener EC...Fatihoglu OU	30654143	2019
7	Transposition procedures in Duane retraction syndrome. ³⁸	Doyle JJ...Hunter DG	30586616	2019
8	Marcus Gunn Jaw-Winking Syndrome Associated with Morning Glory Disc Anomaly. ³⁸	Alshamrani AA...Al Shamrani M	31114123	2019
9	Management of Duane retraction syndrome: A simplified approach. ³⁸	Gaur N...Sharma P	30574884	2019
10	Auditory brainstem response. ³⁸	Eggermont JJ	31277868	2019
11	Duane Retraction Syndrome: Clinical Features and a Case Group-Specific Surgical Approach. ³⁸	Gunduz A...Ulucan PB	30516080	2019
12	Chromosomal microarray analysis of patients with Duane retraction syndrome. ³⁸	Niyaz L...Kara N	30478753	2018
13	Ptosis in childhood: A clinical sign of several disorders: Case series reports and literature review. ³⁸	Pavone P...Jin DK	30200099	2018
14	Protocadherin-Mediated Cell Repulsion Controls the Central Topography and Efferent Projections of the Abducens Nucleus. ³⁸	Asakawa K...Kawakami K	30089266	2018
15	A mutation in transcription factor MAFB causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome. ³⁸	Sato Y...Yoshimura A	29779709	2018
16	Augmented superior rectus transposition procedure in Duane retraction syndrome compared with sixth nerve palsy. ³⁸	Akbari M...Fard MA	29299740	2018
17	The Efficacy of Bilateral Lateral Rectus Recession According to Secondary Deviation Measurements in Unilateral Exotropic Duane Retraction Syndrome. ³⁸	Mezad-Koursh D...Stolovich C	28991345	2018
18	Surgical treatment of Duane retraction syndrome. ³⁸	Akbari MR...Mirmohammadsadeghi A	29270470	2017
19	CHN1 gene mutation analysis in patients with Duane retraction syndrome. ³⁸	Biler ED...Uretmen O	29031989	2017
20	Anomalous Lateral Rectus Muscle Band in a Case of Duane Retraction Syndrome. ³⁸	Ganesh S...Sethi S	29135308	2017
21	Gustatory lid retraction: an unusual congenital cranial dysinnervation disorder. ³⁸	Khan AO...Khan Z	29107795	2017
22	A TUBB6 mutation is associated with autosomal dominant non-progressive congenital facial palsy, bilateral ptosis and velopharyngeal dysfunction. ³⁸	Fazeli W...Heller R	29016863	2017
23	Extraocular muscle dysinnervation disorder resembling Duane retraction syndrome in a 9-month-old French Bulldog. ³⁸	Mari L...De Risio L	27317499	2017
24	Ocular Causes of Abnormal Head Position: Strabismus Clinic Data. ³⁸	Erkan Turan K...Sanac AS	28845325	2017
25	Ocular congenital cranial dysinnervation disorders (CCDDs): insights into axon growth and guidance. ³⁸	Whitman MC...Engle EC	28459979	2017
26	Imaging of Cranial Nerves III, IV, VI in Congenital Cranial Dysinnervation Disorders. ³⁸	Kim JH...Hwang JM	28534340	2017
27	Postoperative full abduction in a patient of Duane retraction syndrome without an abducens nerve: a case report. ³⁸	Kim JH...Hwang JM	28526001	2017
28	Mutant α2-chimaerin signals via bidirectional ephrin pathways in Duane retraction syndrome. ³⁸	Nugent AA...Engle EC	28346224	2017
29	A High Prevalence of Exotropia in Patients With Duane Retraction Syndrome in a Tertiary Eye Care Center in South India. ³⁸	Bhate M...Kekunnaya R	27977037	2017
30	Duane retraction syndrome: causes, effects and management strategies. ³⁸	Kekunnaya R...Negalur M	29133973	2017
31	Management of Duane retraction syndrome with prismatic glasses. ³⁸	Aygit ED...Gokyigit B	28442887	2017
32	Y-splitting with recession of lateral rectus versus lateral rectus recession in correcting upshoot in Duane retraction syndrome. ³⁸	Lin MC	29018752	2017
33	Unilateral lateral rectus cysticercosis presenting as Duane retraction syndrome type IIb. ³⁸	Prasad P...Chaudhary SK	28084290	2017
34	Exotropic Duane syndrome with synergistic divergence and no mutations in COL25A1. ³⁸	Khan AO...Al-Tassan NA	27663630	2016
35	[Identification of a novel JAG1 mutation in a family affected by Alagille syndrome]. ³⁸	Cheng Y...Song YZ	27817779	2016
36	Y-split recession vs isolated recession of the lateral rectus muscle in the treatment of vertical shooting in exotropic Duane retraction syndrome. ³⁸	Farid MF	26833229	2016
37	A simple and novel grading method for retraction and overshoot in Duane retraction syndrome. ³⁸	Kekunnaya R...Sachdeva V	27574176	2016
38	The genetics of nonsyndromic bilateral Duane retraction syndrome. ³⁸	Abu-Amero KK...Bosley TM	27658539	2016
39	Duane retraction syndrome in a patient with Duchenne muscular dystrophy. ³⁸	Bosley TM...Abu-Amero KK	26849454	2016
40	Loss of MAFB Function in Humans and Mice Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects. ³⁸	Park JG...Engle EC	27181683	2016
41	Duane Retraction Syndrome Associated with a Small X Chromosome Deletion. ³⁸	Abu-Amero KK...Bosley TM	26891113	2016
42	Bilateral lateral rectus recession in exotropic Duane syndrome with downshoot. ³⁸	Gurung CM...Shrestha P	28242889	2016
43	Growth hormone deficiency and pituitary malformation in a recurrent Cat-Eye syndrome: a family report. ³⁸	Jedraszak G...Morin G	26518262	2015
44	Modified Y-splitting Procedure for the Treatment of Duane Retraction Syndrome. ³⁸	Altintas AG...Koklu SG	27800223	2015
45	Nicotinic Receptor Mutation in a Mildly Dysmorphic Girl with Duane Retraction Syndrome. ³⁸	Abu-Amero KK...Bosley TM	24001015	2015
46	Comparison of augmented superior rectus transposition with medial rectus recession for surgical management of esotropic Duane retraction syndrome. ³⁸	Tibrewal S...Kekunnaya R	26059662	2015
47	Duane retraction syndrome type 1 with Usher syndrome type 2: an unreported association. ³⁸	Khurana BP...Grover S	25955520	2015
48	Congenital cranial dysinnervation disorder in a boy with congenital mirror movements. ³⁸	Al Shamrani M...Khan AO	25838174	2015
49	Partial duplication of chromosome 19 associated with syndromic duane retraction syndrome. ³⁸	Abu-Amero KK...Bosley TM	23952617	2015
50	Respond to: Management of exotropic Duane retraction syndrome. ³⁸	Sharma P...Sharma A	25971189	2015

Sources

Genes for Isolated Duane Retraction Syndrome

Sources

Variations for Isolated Duane Retraction Syndrome

Sources

Expression for Isolated Duane Retraction Syndrome

Search GEO for disease gene expression data for Isolated Duane Retraction Syndrome.

Sources

Pathways for Isolated Duane Retraction Syndrome

Sources

GO Terms for Isolated Duane Retraction Syndrome

Sources

Sources for Isolated Duane Retraction Syndrome

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HGMD

³¹ HMDB

³² HPO

³³ ICD10

³⁴ ICD10 via Orphanet

³⁵ ICD9CM

³⁶ IUPHAR

³⁷ KEGG

³⁸ LifeMap

³⁹ LncRNADisease

⁴⁰ LOVD

⁴¹ MalaCards

⁴² MedGen

⁴³ MedlinePlus

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NIH Rare Diseases

⁵⁴ NINDS

⁵⁵ Novoseek

⁵⁶ Novus Biologicals

⁵⁷ OMIM

⁵⁸ OMIM via Orphanet

⁵⁹ Orphanet

⁶⁰ PathCards

⁶¹ PharmGKB

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ TGDB

⁷¹ Tocris

⁷² UMLS

⁷³ UMLS via Orphanet

⁷⁴ UniProtKB/Swiss-Prot

⁷⁵ Wikipedia