MCID: ISL019
MIFTS: 22

Isolated Duane Retraction Syndrome

Categories: Eye diseases

Aliases & Classifications for Isolated Duane Retraction Syndrome

MalaCards integrated aliases for Isolated Duane Retraction Syndrome:

Name: Isolated Duane Retraction Syndrome 25
Duane Retraction Syndrome 25 71
Co-Contractive Retraction Syndrome 25
Stilling-Turk-Duane Syndrome 25
Ocular Retraction Syndrome 25
Duane Anomaly, Isolated 25
Duane's Syndrome 25
Duane Syndrome 25

Classifications:



External Ids:

UMLS 71 C0013261

Summaries for Isolated Duane Retraction Syndrome

Genetics Home Reference : 25 Isolated Duane retraction syndrome is a disorder of eye movement. This condition prevents outward movement of the eye (toward the ear), and in some cases may also limit inward eye movement (toward the nose). As the eye moves inward, the eyelids partially close and the eyeball pulls back (retracts) into its socket. Most commonly, only one eye is affected. About 10 percent of people with isolated Duane retraction syndrome develop amblyopia ("lazy eye"), a condition that causes vision loss in the affected eye. About 70 percent of all cases of Duane retraction syndrome are isolated, which means they occur without other signs and symptoms. Duane retraction syndrome can also occur as part of syndromes that affect other areas of the body. For example, Duane-radial ray syndrome is characterized by this eye disorder in conjunction with abnormalities of bones in the arms and hands. Researchers have identified three forms of isolated Duane retraction syndrome, designated types I, II, and III. The types vary in which eye movements are most severely restricted (inward, outward, or both). All three types are characterized by retraction of the eyeball as the eye moves inward.

MalaCards based summary : Isolated Duane Retraction Syndrome, also known as duane retraction syndrome, is related to duane retraction syndrome 1 and duane retraction syndrome, and has symptoms including ophthalmoparesis and ophthalmoplegia. Affiliated tissues include eye, bone and pituitary.

Related Diseases for Isolated Duane Retraction Syndrome

Diseases related to Isolated Duane Retraction Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 157)
# Related Disease Score Top Affiliating Genes
1 duane retraction syndrome 1 12.4
2 duane retraction syndrome 11.8
3 duane-radial ray syndrome 11.7
4 wildervanck syndrome 11.5
5 strabismus 10.6
6 monocular esotropia 10.6
7 mechanical strabismus 10.6
8 esotropia 10.6
9 alternating exotropia 10.4
10 exotropia 10.4
11 ptosis 10.2
12 cataract 10.2
13 retinitis pigmentosa 10.2
14 sensorineural hearing loss 10.2
15 neuroretinitis 10.2
16 retinitis 10.2
17 torticollis 10.2
18 suppression amblyopia 10.2
19 amblyopia 10.2
20 abducens nerve disease 10.2
21 branchiootic syndrome 1 10.1
22 meningioma, radiation-induced 10.0
23 meningioma, familial 10.0
24 spinal meningioma 10.0
25 secretory meningioma 10.0
26 lymphoplasmacyte-rich meningioma 10.0
27 achondroplasia 10.0
28 autoimmune disease 10.0
29 cleft palate, isolated 10.0
30 frontonasal dysplasia 1 10.0
31 solitary median maxillary central incisor 10.0
32 marfan syndrome 10.0
33 chromosome 9p deletion syndrome 10.0
34 dowling-degos disease 1 10.0
35 neural tube defects 10.0
36 charge syndrome 10.0
37 muscular dystrophy, duchenne type 10.0
38 retinitis pigmentosa-deafness syndrome 10.0
39 oculoauriculofrontonasal syndrome 10.0
40 astigmatism 10.0
41 polydactyly 10.0
42 tukel syndrome 10.0
43 chromosome 16p13.3 deletion syndrome, proximal 10.0
44 alacrima, achalasia, and mental retardation syndrome 10.0
45 usher syndrome 10.0
46 usher syndrome type 2 10.0
47 cysticercosis 10.0
48 klippel-feil syndrome 10.0
49 myopia 10.0
50 focal segmental glomerulosclerosis 10.0

Graphical network of the top 20 diseases related to Isolated Duane Retraction Syndrome:



Diseases related to Isolated Duane Retraction Syndrome

Symptoms & Phenotypes for Isolated Duane Retraction Syndrome

UMLS symptoms related to Isolated Duane Retraction Syndrome:


ophthalmoparesis, ophthalmoplegia

Drugs & Therapeutics for Isolated Duane Retraction Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies Recruiting NCT03059420

Search NIH Clinical Center for Isolated Duane Retraction Syndrome

Genetic Tests for Isolated Duane Retraction Syndrome

Anatomical Context for Isolated Duane Retraction Syndrome

MalaCards organs/tissues related to Isolated Duane Retraction Syndrome:

40
Eye, Bone, Pituitary, Brain, Heart, Colon, Skin

Publications for Isolated Duane Retraction Syndrome

Articles related to Isolated Duane Retraction Syndrome:

(show top 50) (show all 193)
# Title Authors PMID Year
1
Reoperation in esotropic Duane retraction syndrome: Long-term motor outcome of superior rectus transposition. 61
31888377 2019
2
Combined surgical strategy for management of unilateral exotropic Duane retraction syndrome associated with limitation of abduction. 61
31689501 2019
3
Facial Asymmetry in Unilateral Duane Retraction Syndrome. 61
31834151 2019
4
Phenotypic analysis of mice carrying human-type MAFB p.Leu239Pro mutation. 61
31882119 2019
5
The clinical characteristics of Duane retraction syndrome in Al-Medina region. 61
31920443 2019
6
Chromosomal microarray analysis of patients with Duane retraction syndrome. 61
30478753 2019
7
Oculo-Auriculo-Fronto-Nasal Syndrome With Duane Retraction Syndrome and Dysplastic Bony Structure in the Midline of Nose. 61
31756883 2019
8
A modified technique for attaching the lateral rectus muscle to the orbital periosteum through a skin incision over the lateral orbital rim. 61
31103564 2019
9
Diffusion Tensor Imaging of the Lateral Rectus Muscle in Duane Retraction Syndrome. 61
31082953 2019
10
Diffusion Tensor Imaging of the Lateral Rectus Muscle in Duane Retraction Syndrome. 61
31082973 2019
11
Binocular Function in Subjects with Orthotropic Duane Retraction Syndrome. 61
31034344 2019
12
Absent cochlear and abducens nerves in a patient with Duane retraction syndrome. 61
30377846 2019
13
Botulinum toxin-A injection in esotropic Duane syndrome patients up to 2 years of age. 61
30654143 2019
14
Transposition procedures in Duane retraction syndrome. 61
30586616 2019
15
Marcus Gunn Jaw-Winking Syndrome Associated with Morning Glory Disc Anomaly. 61
31114123 2019
16
Duane retraction syndrome in a patient with abnormal head position. 61
31619934 2019
17
Management of Duane retraction syndrome: A simplified approach. 61
30574884 2019
18
Auditory brainstem response. 61
31277868 2019
19
Duane Retraction Syndrome: Clinical Features and a Case Group-Specific Surgical Approach. 61
30516080 2019
20
Ptosis in childhood: A clinical sign of several disorders: Case series reports and literature review. 61
30200099 2018
21
Protocadherin-Mediated Cell Repulsion Controls the Central Topography and Efferent Projections of the Abducens Nucleus. 61
30089266 2018
22
A mutation in transcription factor MAFB causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome. 61
29779709 2018
23
Augmented superior rectus transposition procedure in Duane retraction syndrome compared with sixth nerve palsy. 61
29299740 2018
24
The Efficacy of Bilateral Lateral Rectus Recession According to Secondary Deviation Measurements in Unilateral Exotropic Duane Retraction Syndrome. 61
28991345 2018
25
Surgical treatment of Duane retraction syndrome. 61
29270470 2017
26
Anomalous Lateral Rectus Muscle Band in a Case of Duane Retraction Syndrome. 61
29135308 2017
27
CHN1 gene mutation analysis in patients with Duane retraction syndrome. 61
29031989 2017
28
Gustatory lid retraction: an unusual congenital cranial dysinnervation disorder. 61
29107795 2017
29
A TUBB6 mutation is associated with autosomal dominant non-progressive congenital facial palsy, bilateral ptosis and velopharyngeal dysfunction. 61
29016863 2017
30
Extraocular muscle dysinnervation disorder resembling Duane retraction syndrome in a 9-month-old French Bulldog. 61
27317499 2017
31
Ocular Causes of Abnormal Head Position: Strabismus Clinic Data. 61
28845325 2017
32
Ocular congenital cranial dysinnervation disorders (CCDDs): insights into axon growth and guidance. 61
28459979 2017
33
Imaging of Cranial Nerves III, IV, VI in Congenital Cranial Dysinnervation Disorders. 61
28534340 2017
34
Postoperative full abduction in a patient of Duane retraction syndrome without an abducens nerve: a case report. 61
28526001 2017
35
Mutant α2-chimaerin signals via bidirectional ephrin pathways in Duane retraction syndrome. 61
28346224 2017
36
A High Prevalence of Exotropia in Patients With Duane Retraction Syndrome in a Tertiary Eye Care Center in South India. 61
27977037 2017
37
Duane retraction syndrome: causes, effects and management strategies. 61
29133973 2017
38
Y-splitting with recession of lateral rectus versus lateral rectus recession in correcting upshoot in Duane retraction syndrome. 61
29018752 2017
39
Unilateral lateral rectus cysticercosis presenting as Duane retraction syndrome type IIb. 61
28084290 2017
40
Management of Duane retraction syndrome with prismatic glasses. 61
28442887 2017
41
Exotropic Duane syndrome with synergistic divergence and no mutations in COL25A1. 61
27663630 2016
42
[Identification of a novel JAG1 mutation in a family affected by Alagille syndrome]. 61
27817779 2016
43
A simple and novel grading method for retraction and overshoot in Duane retraction syndrome. 61
27574176 2016
44
Y-split recession vs isolated recession of the lateral rectus muscle in the treatment of vertical shooting in exotropic Duane retraction syndrome. 61
26833229 2016
45
The genetics of nonsyndromic bilateral Duane retraction syndrome. 61
27658539 2016
46
Duane retraction syndrome in a patient with Duchenne muscular dystrophy. 61
26849454 2016
47
Loss of MAFB Function in Humans and Mice Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects. 61
27181683 2016
48
Duane Retraction Syndrome Associated with a Small X Chromosome Deletion. 61
26891113 2016
49
Bilateral lateral rectus recession in exotropic Duane syndrome with downshoot. 61
28242889 2016
50
Growth hormone deficiency and pituitary malformation in a recurrent Cat-Eye syndrome: a family report. 61
26518262 2015

Variations for Isolated Duane Retraction Syndrome

Expression for Isolated Duane Retraction Syndrome

Search GEO for disease gene expression data for Isolated Duane Retraction Syndrome.

Pathways for Isolated Duane Retraction Syndrome

GO Terms for Isolated Duane Retraction Syndrome

Sources for Isolated Duane Retraction Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
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30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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44 MESH via Orphanet
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48 NCI
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50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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