MCID: ISL019
MIFTS: 23

Isolated Duane Retraction Syndrome

Categories: Eye diseases

Aliases & Classifications for Isolated Duane Retraction Syndrome

MalaCards integrated aliases for Isolated Duane Retraction Syndrome:

Name: Isolated Duane Retraction Syndrome 25
Duane Retraction Syndrome 25 72
Co-Contractive Retraction Syndrome 25
Stilling-Turk-Duane Syndrome 25
Ocular Retraction Syndrome 25
Duane Anomaly, Isolated 25
Duane's Syndrome 25
Duane Syndrome 25

Classifications:



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UMLS 72 C0013261

Summaries for Isolated Duane Retraction Syndrome

Genetics Home Reference : 25 Isolated Duane retraction syndrome is a disorder of eye movement. This condition prevents outward movement of the eye (toward the ear), and in some cases may also limit inward eye movement (toward the nose). As the eye moves inward, the eyelids partially close and the eyeball pulls back (retracts) into its socket. Most commonly, only one eye is affected. About 10 percent of people with isolated Duane retraction syndrome develop amblyopia ("lazy eye"), a condition that causes vision loss in the affected eye. About 70 percent of all cases of Duane retraction syndrome are isolated, which means they occur without other signs and symptoms. Duane retraction syndrome can also occur as part of syndromes that affect other areas of the body. For example, Duane-radial ray syndrome is characterized by this eye disorder in conjunction with abnormalities of bones in the arms and hands. Researchers have identified three forms of isolated Duane retraction syndrome, designated types I, II, and III. The types vary in which eye movements are most severely restricted (inward, outward, or both). All three types are characterized by retraction of the eyeball as the eye moves inward.

MalaCards based summary : Isolated Duane Retraction Syndrome, also known as duane retraction syndrome, is related to duane syndrome type 1 and duane syndrome type 3, and has symptoms including ophthalmoparesis and ophthalmoplegia. Affiliated tissues include eye, bone and brain.

Related Diseases for Isolated Duane Retraction Syndrome

Diseases related to Isolated Duane Retraction Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 161)
# Related Disease Score Top Affiliating Genes
1 duane syndrome type 1 12.7
2 duane syndrome type 3 12.6
3 duane syndrome type 2 12.5
4 duane retraction syndrome 1 12.4
5 duane retraction syndrome 11.8
6 duane-radial ray syndrome 11.7
7 wildervanck syndrome 11.5
8 monocular esotropia 10.6
9 esotropia 10.6
10 strabismus 10.6
11 mechanical strabismus 10.6
12 alternating exotropia 10.4
13 exotropia 10.4
14 ptosis 10.2
15 cataract 10.2
16 retinitis pigmentosa 10.2
17 sensorineural hearing loss 10.2
18 neuroretinitis 10.2
19 retinitis 10.2
20 torticollis 10.2
21 suppression amblyopia 10.2
22 amblyopia 10.2
23 abducens nerve disease 10.2
24 branchiootic syndrome 1 10.1
25 meningioma, radiation-induced 10.0
26 meningioma, familial 10.0
27 spinal meningioma 10.0
28 secretory meningioma 10.0
29 lymphoplasmacyte-rich meningioma 10.0
30 achondroplasia 10.0
31 autoimmune disease 10.0
32 cleft palate, isolated 10.0
33 solitary median maxillary central incisor 10.0
34 marfan syndrome 10.0
35 chromosome 9p deletion syndrome 10.0
36 dowling-degos disease 1 10.0
37 neural tube defects 10.0
38 c syndrome 10.0
39 charge syndrome 10.0
40 muscular dystrophy, duchenne type 10.0
41 retinitis pigmentosa-deafness syndrome 10.0
42 astigmatism 10.0
43 polydactyly 10.0
44 tukel syndrome 10.0
45 chromosome 16p13.3 deletion syndrome, proximal 10.0
46 alacrima, achalasia, and mental retardation syndrome 10.0
47 usher syndrome 10.0
48 usher syndrome type 2 10.0
49 cysticercosis 10.0
50 klippel-feil syndrome 10.0

Graphical network of the top 20 diseases related to Isolated Duane Retraction Syndrome:



Diseases related to Isolated Duane Retraction Syndrome

Symptoms & Phenotypes for Isolated Duane Retraction Syndrome

UMLS symptoms related to Isolated Duane Retraction Syndrome:


ophthalmoparesis, ophthalmoplegia

Drugs & Therapeutics for Isolated Duane Retraction Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies Recruiting NCT03059420

Search NIH Clinical Center for Isolated Duane Retraction Syndrome

Genetic Tests for Isolated Duane Retraction Syndrome

Anatomical Context for Isolated Duane Retraction Syndrome

MalaCards organs/tissues related to Isolated Duane Retraction Syndrome:

41
Eye, Bone, Brain, Colon, Heart, Skin, Pituitary

Publications for Isolated Duane Retraction Syndrome

Articles related to Isolated Duane Retraction Syndrome:

(show top 50) (show all 186)
# Title Authors PMID Year
1
A modified technique for attaching the lateral rectus muscle to the orbital periosteum through a skin incision over the lateral orbital rim. 38
31103564 2019
2
Diffusion Tensor Imaging of the Lateral Rectus Muscle in Duane Retraction Syndrome. 38
31082973 2019
3
Diffusion Tensor Imaging of the Lateral Rectus Muscle in Duane Retraction Syndrome. 38
31082953 2019
4
Binocular Function in Subjects with Orthotropic Duane Retraction Syndrome. 38
31034344 2019
5
Absent cochlear and abducens nerves in a patient with Duane retraction syndrome. 38
30377846 2019
6
Botulinum toxin-A injection in esotropic Duane syndrome patients up to 2 years of age. 38
30654143 2019
7
Transposition procedures in Duane retraction syndrome. 38
30586616 2019
8
Marcus Gunn Jaw-Winking Syndrome Associated with Morning Glory Disc Anomaly. 38
31114123 2019
9
Management of Duane retraction syndrome: A simplified approach. 38
30574884 2019
10
Auditory brainstem response. 38
31277868 2019
11
Duane Retraction Syndrome: Clinical Features and a Case Group-Specific Surgical Approach. 38
30516080 2019
12
Chromosomal microarray analysis of patients with Duane retraction syndrome. 38
30478753 2018
13
Ptosis in childhood: A clinical sign of several disorders: Case series reports and literature review. 38
30200099 2018
14
Protocadherin-Mediated Cell Repulsion Controls the Central Topography and Efferent Projections of the Abducens Nucleus. 38
30089266 2018
15
A mutation in transcription factor MAFB causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome. 38
29779709 2018
16
Augmented superior rectus transposition procedure in Duane retraction syndrome compared with sixth nerve palsy. 38
29299740 2018
17
The Efficacy of Bilateral Lateral Rectus Recession According to Secondary Deviation Measurements in Unilateral Exotropic Duane Retraction Syndrome. 38
28991345 2018
18
Surgical treatment of Duane retraction syndrome. 38
29270470 2017
19
CHN1 gene mutation analysis in patients with Duane retraction syndrome. 38
29031989 2017
20
Anomalous Lateral Rectus Muscle Band in a Case of Duane Retraction Syndrome. 38
29135308 2017
21
Gustatory lid retraction: an unusual congenital cranial dysinnervation disorder. 38
29107795 2017
22
A TUBB6 mutation is associated with autosomal dominant non-progressive congenital facial palsy, bilateral ptosis and velopharyngeal dysfunction. 38
29016863 2017
23
Extraocular muscle dysinnervation disorder resembling Duane retraction syndrome in a 9-month-old French Bulldog. 38
27317499 2017
24
Ocular Causes of Abnormal Head Position: Strabismus Clinic Data. 38
28845325 2017
25
Ocular congenital cranial dysinnervation disorders (CCDDs): insights into axon growth and guidance. 38
28459979 2017
26
Imaging of Cranial Nerves III, IV, VI in Congenital Cranial Dysinnervation Disorders. 38
28534340 2017
27
Postoperative full abduction in a patient of Duane retraction syndrome without an abducens nerve: a case report. 38
28526001 2017
28
Mutant α2-chimaerin signals via bidirectional ephrin pathways in Duane retraction syndrome. 38
28346224 2017
29
A High Prevalence of Exotropia in Patients With Duane Retraction Syndrome in a Tertiary Eye Care Center in South India. 38
27977037 2017
30
Duane retraction syndrome: causes, effects and management strategies. 38
29133973 2017
31
Management of Duane retraction syndrome with prismatic glasses. 38
28442887 2017
32
Y-splitting with recession of lateral rectus versus lateral rectus recession in correcting upshoot in Duane retraction syndrome. 38
29018752 2017
33
Unilateral lateral rectus cysticercosis presenting as Duane retraction syndrome type IIb. 38
28084290 2017
34
Exotropic Duane syndrome with synergistic divergence and no mutations in COL25A1. 38
27663630 2016
35
[Identification of a novel JAG1 mutation in a family affected by Alagille syndrome]. 38
27817779 2016
36
Y-split recession vs isolated recession of the lateral rectus muscle in the treatment of vertical shooting in exotropic Duane retraction syndrome. 38
26833229 2016
37
A simple and novel grading method for retraction and overshoot in Duane retraction syndrome. 38
27574176 2016
38
The genetics of nonsyndromic bilateral Duane retraction syndrome. 38
27658539 2016
39
Duane retraction syndrome in a patient with Duchenne muscular dystrophy. 38
26849454 2016
40
Loss of MAFB Function in Humans and Mice Causes Duane Syndrome, Aberrant Extraocular Muscle Innervation, and Inner-Ear Defects. 38
27181683 2016
41
Duane Retraction Syndrome Associated with a Small X Chromosome Deletion. 38
26891113 2016
42
Bilateral lateral rectus recession in exotropic Duane syndrome with downshoot. 38
28242889 2016
43
Growth hormone deficiency and pituitary malformation in a recurrent Cat-Eye syndrome: a family report. 38
26518262 2015
44
Modified Y-splitting Procedure for the Treatment of Duane Retraction Syndrome. 38
27800223 2015
45
Nicotinic Receptor Mutation in a Mildly Dysmorphic Girl with Duane Retraction Syndrome. 38
24001015 2015
46
Comparison of augmented superior rectus transposition with medial rectus recession for surgical management of esotropic Duane retraction syndrome. 38
26059662 2015
47
Duane retraction syndrome type 1 with Usher syndrome type 2: an unreported association. 38
25955520 2015
48
Congenital cranial dysinnervation disorder in a boy with congenital mirror movements. 38
25838174 2015
49
Partial duplication of chromosome 19 associated with syndromic duane retraction syndrome. 38
23952617 2015
50
Respond to: Management of exotropic Duane retraction syndrome. 38
25971189 2015

Variations for Isolated Duane Retraction Syndrome

Expression for Isolated Duane Retraction Syndrome

Search GEO for disease gene expression data for Isolated Duane Retraction Syndrome.

Pathways for Isolated Duane Retraction Syndrome

GO Terms for Isolated Duane Retraction Syndrome

Sources for Isolated Duane Retraction Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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