MCID: ISL019
MIFTS: 21

Isolated Duane Retraction Syndrome

Categories: Eye diseases

Aliases & Classifications for Isolated Duane Retraction Syndrome

MalaCards integrated aliases for Isolated Duane Retraction Syndrome:

Name: Isolated Duane Retraction Syndrome 43
Duane Retraction Syndrome 43 71
Co-Contractive Retraction Syndrome 43
Stilling-Turk-Duane Syndrome 43
Ocular Retraction Syndrome 43
Duane Anomaly, Isolated 43
Duane's Syndrome 43
Duane Syndrome 43

Classifications:



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UMLS 71 C0013261

Summaries for Isolated Duane Retraction Syndrome

MedlinePlus Genetics : 43 Isolated Duane retraction syndrome is a disorder of eye movement. This condition prevents outward movement of the eye (toward the ear), and in some cases may also limit inward eye movement (toward the nose). As the eye moves inward, the eyelids partially close and the eyeball pulls back (retracts) into its socket. Most commonly, only one eye is affected. About 10 percent of people with isolated Duane retraction syndrome develop amblyopia ("lazy eye"), a condition that causes vision loss in the affected eye.About 70 percent of all cases of Duane retraction syndrome are isolated, which means they occur without other signs and symptoms. Duane retraction syndrome can also occur as part of syndromes that affect other areas of the body. For example, Duane-radial ray syndrome is characterized by this eye disorder in conjunction with abnormalities of bones in the arms and hands.Researchers have identified three forms of isolated Duane retraction syndrome, designated types I, II, and III. The types vary in which eye movements are most severely restricted (inward, outward, or both). All three types are characterized by retraction of the eyeball as the eye moves inward.

MalaCards based summary : Isolated Duane Retraction Syndrome, also known as duane retraction syndrome, is related to duane retraction syndrome 1 and duane retraction syndrome, and has symptoms including ophthalmoplegia and ophthalmoparesis. Affiliated tissues include eye, colon and pituitary.

Related Diseases for Isolated Duane Retraction Syndrome

Diseases related to Isolated Duane Retraction Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 154)
# Related Disease Score Top Affiliating Genes
1 duane retraction syndrome 1 11.8
2 duane retraction syndrome 11.3
3 athabaskan brainstem dysgenesis syndrome 11.2
4 duane-radial ray syndrome 11.2
5 wildervanck syndrome 11.0
6 monocular esotropia 10.6
7 esotropia 10.6
8 strabismus 10.6
9 mechanical strabismus 10.6
10 alternating exotropia 10.4
11 exotropia 10.4
12 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.3
13 myopia 10.3
14 torticollis 10.2
15 ptosis 10.2
16 suppression amblyopia 10.2
17 amblyopia 10.2
18 retinitis pigmentosa 10.2
19 alacrima, achalasia, and mental retardation syndrome 10.2
20 sensorineural hearing loss 10.2
21 neuroretinitis 10.2
22 retinitis 10.2
23 abducens nerve disease 10.1
24 branchiootic syndrome 1 10.1
25 enophthalmos 10.1
26 cataract 10.1
27 achondroplasia 10.0
28 cleft palate, isolated 10.0
29 frontonasal dysplasia 1 10.0
30 solitary median maxillary central incisor 10.0
31 marfan syndrome 10.0
32 chromosome 9p deletion syndrome 10.0
33 dowling-degos disease 1 10.0
34 neural tube defects 10.0
35 vater/vacterl association 10.0
36 charge syndrome 10.0
37 muscular dystrophy, duchenne type 10.0
38 otopalatodigital syndrome, type i 10.0
39 retinitis pigmentosa-deafness syndrome 10.0
40 oculoauriculofrontonasal syndrome 10.0
41 astigmatism 10.0
42 polydactyly 10.0
43 chromosome 1p36 deletion syndrome 10.0
44 tukel syndrome 10.0
45 chromosome 16p13.3 deletion syndrome, proximal 10.0
46 usher syndrome 10.0
47 usher syndrome type 2 10.0
48 cysticercosis 10.0
49 klippel-feil syndrome 10.0
50 focal segmental glomerulosclerosis 10.0

Graphical network of the top 20 diseases related to Isolated Duane Retraction Syndrome:



Diseases related to Isolated Duane Retraction Syndrome

Symptoms & Phenotypes for Isolated Duane Retraction Syndrome

UMLS symptoms related to Isolated Duane Retraction Syndrome:


ophthalmoplegia, ophthalmoparesis

Drugs & Therapeutics for Isolated Duane Retraction Syndrome

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Genetic Studies of Strabismus, Congenital Cranial Dysinnervation Disorders (CCDDs), and Their Associated Anomalies Recruiting NCT03059420

Search NIH Clinical Center for Isolated Duane Retraction Syndrome

Genetic Tests for Isolated Duane Retraction Syndrome

Anatomical Context for Isolated Duane Retraction Syndrome

MalaCards organs/tissues related to Isolated Duane Retraction Syndrome:

40
Eye, Colon, Pituitary

Publications for Isolated Duane Retraction Syndrome

Articles related to Isolated Duane Retraction Syndrome:

(show top 50) (show all 212)
# Title Authors PMID Year
1
Imaging of congenital cranial dysinnervation disorders: What radiologist wants to know? 61
33189029 2021
2
The presence of anomalous extraocular bands in Duane retraction syndrome. 61
33601039 2021
3
Bilateral augmented superior rectus transposition with medial rectus recession for bilateral esotropic Duane retraction syndrome. 61
33601043 2021
4
Variant types of Duane retraction syndrome: synergistic divergences and convergences. 61
33607271 2021
5
Surgical Outcomes of Exotropic Duane Retraction Syndrome From a Tertiary Eye Care Center. 61
33495792 2021
6
Augmented superior rectus muscle transposition in management of defective ocular abduction. 61
33472581 2021
7
A rare association of type 2 Duanes retraction syndrome with arthrogryposis multiplex congenita. 61
33480805 2021
8
Contralateral lateral rectus muscle recession in a patient with unilateral exotropic Duane retraction syndrome type II: A case report. 61
33455502 2021
9
Effect of lateral rectus muscle resection on abduction in Duane retraction syndrome type 1. 61
33185820 2020
10
Outcomes of symmetric bilateral medial rectus recession in large-angle esotropic Duane syndrome. 61
33148050 2020
11
Hummelsheim procedure combined with medial rectus recession in complete sixth nerve palsy and esotropic Duane Retraction Syndrome. 61
33228408 2020
12
Identification of a novel CHN1 p.(Phe213Val) variant in a large Han Chinese family with congenital Duane retraction syndrome. 61
33004823 2020
13
Ocular structural changes in patients with Duane retraction syndrome: Does a correlation exist? 61
32971639 2020
14
William F. Hoyt's Role in Identifying the Pathogenesis of Duane Retraction Syndrome. 61
32796341 2020
15
Superior Rectus Transposition With Medial Rectus Recession Versus Medial Rectus Recession in Esotropic Duane Retraction Syndrome. 61
32956481 2020
16
Duane-minus (Duane sine retraction and Duane sine limitation): possible incomplete forms of Duane retraction syndrome. 61
32839562 2020
17
Surgical outcome of patients with unilateral exotropic Duane retraction syndrome. 61
32479998 2020
18
Clinical Features of Duane Retraction Syndrome: A New Classification. 61
32233150 2020
19
Phenotypic analysis of mice carrying human-type MAFB p.Leu239Pro mutation. 61
31882119 2020
20
Non-classical 1p36 deletion in a patient with Duane retraction syndrome: case report and literature review. 61
32939224 2020
21
Unilateral Duane Retraction Syndrome Associated with Unilateral Congenital Cataract. 61
32095213 2020
22
Facial Asymmetry in Unilateral Duane Retraction Syndrome. 61
31834151 2019
23
Combined surgical strategy for management of unilateral exotropic Duane retraction syndrome associated with limitation of abduction. 61
31689501 2019
24
Reoperation in esotropic Duane retraction syndrome: Long-term motor outcome of superior rectus transposition. 61
31888377 2019
25
The clinical characteristics of Duane retraction syndrome in Al-Medina region. 61
31920443 2019
26
Chromosomal microarray analysis of patients with Duane retraction syndrome. 61
30478753 2019
27
Oculo-Auriculo-Fronto-Nasal Syndrome With Duane Retraction Syndrome and Dysplastic Bony Structure in the Midline of Nose. 61
31756883 2019
28
A modified technique for attaching the lateral rectus muscle to the orbital periosteum through a skin incision over the lateral orbital rim. 61
31103564 2019
29
Diffusion Tensor Imaging of the Lateral Rectus Muscle in Duane Retraction Syndrome. 61
31082953 2019
30
Binocular Function in Subjects with Orthotropic Duane Retraction Syndrome. 61
31034344 2019
31
Absent cochlear and abducens nerves in a patient with Duane retraction syndrome. 61
30377846 2019
32
Botulinum toxin-A injection in esotropic Duane syndrome patients up to 2 years of age. 61
30654143 2019
33
Transposition procedures in Duane retraction syndrome. 61
30586616 2019
34
Marcus Gunn Jaw-Winking Syndrome Associated with Morning Glory Disc Anomaly. 61
31114123 2019
35
Duane retraction syndrome in a patient with abnormal head position. 61
31619934 2019
36
Management of Duane retraction syndrome: A simplified approach. 61
30574884 2019
37
Auditory brainstem response. 61
31277868 2019
38
Duane Retraction Syndrome: Clinical Features and a Case Group-Specific Surgical Approach. 61
30516080 2019
39
Ptosis in childhood: A clinical sign of several disorders: Case series reports and literature review. 61
30200099 2018
40
Protocadherin-Mediated Cell Repulsion Controls the Central Topography and Efferent Projections of the Abducens Nucleus. 61
30089266 2018
41
A mutation in transcription factor MAFB causes Focal Segmental Glomerulosclerosis with Duane Retraction Syndrome. 61
29779709 2018
42
Augmented superior rectus transposition procedure in Duane retraction syndrome compared with sixth nerve palsy. 61
29299740 2018
43
The Efficacy of Bilateral Lateral Rectus Recession According to Secondary Deviation Measurements in Unilateral Exotropic Duane Retraction Syndrome. 61
28991345 2018
44
Surgical treatment of Duane retraction syndrome. 61
29270470 2017
45
CHN1 gene mutation analysis in patients with Duane retraction syndrome. 61
29031989 2017
46
Anomalous Lateral Rectus Muscle Band in a Case of Duane Retraction Syndrome. 61
29135308 2017
47
Gustatory lid retraction: an unusual congenital cranial dysinnervation disorder. 61
29107795 2017
48
A TUBB6 mutation is associated with autosomal dominant non-progressive congenital facial palsy, bilateral ptosis and velopharyngeal dysfunction. 61
29016863 2017
49
Extraocular muscle dysinnervation disorder resembling Duane retraction syndrome in a 9-month-old French Bulldog. 61
27317499 2017
50
Ocular congenital cranial dysinnervation disorders (CCDDs): insights into axon growth and guidance. 61
28459979 2017

Variations for Isolated Duane Retraction Syndrome

Expression for Isolated Duane Retraction Syndrome

Search GEO for disease gene expression data for Isolated Duane Retraction Syndrome.

Pathways for Isolated Duane Retraction Syndrome

GO Terms for Isolated Duane Retraction Syndrome

Sources for Isolated Duane Retraction Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Mar-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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