MCID: ISL072
MIFTS: 14

Isolated Levocardia

Categories: Rare diseases

Aliases & Classifications for Isolated Levocardia

MalaCards integrated aliases for Isolated Levocardia:

Name: Isolated Levocardia 52
Isolated Levocardia with Situs Inversus 52
Situs Inversus with Levocardia 52

Classifications:



Summaries for Isolated Levocardia

NIH Rare Diseases : 52 Isolated levocardia is a type of situs inversus where the heart is located in the normal position, but there is a mirror-image reversal of other internal organs . Isolated levocardia may occur alone or with heart defects, heart rhythm abnormalities (sick sinus syndrome or atrioventricular node disorder ), spleen defects (absent, underdeveloped, or extra spleen), and intestinal malrotation . Long term outlook varies depending on the presence/absence of associated abnormalities, particularly heart defects. The cause of isolated levocardia is not known. It is not usually associated with chromosome abnormalities .

MalaCards based summary : Isolated Levocardia, also known as isolated levocardia with situs inversus, is related to levocardia and situs inversus. Affiliated tissues include spleen, heart and atrioventricular node.

Related Diseases for Isolated Levocardia

Diseases related to Isolated Levocardia via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 25)
# Related Disease Score Top Affiliating Genes
1 levocardia 11.8
2 situs inversus 10.6
3 congenitally corrected transposition of the great arteries 10.3
4 heart septal defect 10.3
5 duodenal obstruction 10.3
6 visceral heterotaxy 10.3
7 ventricular septal defect 10.3
8 tricuspid valve stenosis 10.2
9 chronic kidney disease 10.2
10 tetralogy of fallot 10.2
11 sick sinus syndrome 10.2
12 intestinal obstruction 10.2
13 dextrocardia 10.2
14 heterotaxy 10.2
15 volvulus of midgut 10.0
16 patent ductus arteriosus 1 10.0
17 cyanosis, transient neonatal 10.0
18 dextro-looped transposition of the great arteries 10.0
19 atrial heart septal defect 10.0
20 splenic abscess 10.0
21 aneurysm of sinus of valsalva 10.0
22 dextrocardia with situs inversus 10.0
23 double discordia 10.0
24 aneurysm 10.0
25 syncope 10.0

Graphical network of the top 20 diseases related to Isolated Levocardia:



Diseases related to Isolated Levocardia

Symptoms & Phenotypes for Isolated Levocardia

Drugs & Therapeutics for Isolated Levocardia

Search Clinical Trials , NIH Clinical Center for Isolated Levocardia

Genetic Tests for Isolated Levocardia

Anatomical Context for Isolated Levocardia

MalaCards organs/tissues related to Isolated Levocardia:

40
Spleen, Heart, Atrioventricular Node, Liver, Lung, Kidney

Publications for Isolated Levocardia

Articles related to Isolated Levocardia:

(show top 50) (show all 54)
# Title Authors PMID Year
1
Tetralogy of Fallot with isolated levocardia in a young female. 61
31258874 2019
2
Ruptured Sinus of Valsalva Aneurysm Associated with Situs Ambiguus, Isolated Levocardia, and Polysplenia. 61
29276443 2017
3
Situs Inversus with Levocardia and Congenitally Corrected Transposition of Great Vessels in a 35 year old Male: A Case report. 61
28243408 2017
4
Situs inversus with levocardia, infrahepatic interruption of the inferior vena cava, and azygos continuation: a case report. 61
25737490 2016
5
Echocardiographic Diagnosis of Isolated Levocardia with D-transposition of Great Arteries. 61
28465957 2016
6
Letter to the editor regarding "Situs inversus with levocardia, infrahepatic interruption of the inferior vena cava, and azygos continuation: a case report". 61
25986555 2015
7
Dynamic left ventricular outflow obstruction in situs inversus with levocardia. 61
26628311 2015
8
Clinics in diagnostic imaging (160). Levocardia with abdominal situs inversus. 61
25917470 2015
9
[A matter of perspective: multimodality imaging of a giant cardiac mass]. 61
25837462 2015
10
Pancreaticoduodenectomy performed in a patient with situs ambiguous accompanied with isolated levocardia, malrotation, and normal spleen. 61
25485244 2014
11
[A case of isolated levocardia with atrial septal defect associated with partial abdominal heterotaxia]. 61
24377898 2013
12
A case of unusual visceral heterotaxy syndrome with isolated levocardia. 61
24255657 2013
13
Prenatal diagnosis of isolated levocardia and a structurally normal heart: two case reports and a review of the literature. 61
22614902 2013
14
Laparoscopic adrenalectomy in a patient with situs inversus levocardia. 61
23256030 2012
15
Situs anomalies on prenatal MRI. 61
21715116 2012
16
Rare case of isolated levocardia with polysplenia including normally structured lung without cardiac anomaly. 61
22103459 2011
17
Situs inversus with levocardia and congenitally corrected transposition of great vessels with rheumatic tricuspid valve stenosis and regurgitation. 61
22574246 2011
18
Prenatal echocardiographic diagnosis of cardiac right/left axis and malpositions according to standardized Cordes technique. 61
21303758 2011
19
The modified Senning procedure as an integral part of an anatomical correction of congenitally corrected transposition of the great arteries. 61
24414198 2011
20
Isolated levocardia: prenatal diagnosis and management. 61
19489955 2009
21
[Clinical analysis of surgical procedures and outcomes for corrected transposition of great arteries with heart anomaly]. 61
18844048 2008
22
Isolated levocardia: prenatal diagnosis, clinical importance, and literature review. 61
17324986 2007
23
Splenic abscess in a boy with isolated levocardia. 61
16190138 2005
24
Neonatal intestinal obstruction with isolated levocardia. 61
10917309 2000
25
A case of malrotation and situs ambiguus. 61
10399216 1999
26
Isolated levocardia associated with absence of inferior vena cava, lobulated spleen and sick sinus syndrome. A case report. 61
9687832 1998
27
Duodenal obstruction with isolated levocardia. 61
8935941 1996
28
[Levocardia with situs inversus (isolated levocardia)]. 61
9117741 1996
29
ISOLATED LEVOCARDIA WITH SITUS INVERSUS (A Case Report). 61
28769192 1994
30
The extracardiac total cavopulmonary connection for definitive conversion to the Fontan circulation: summary of early experience and results. 61
8219531 1993
31
[A successful operation of isolated levocardia with left atrial isomerism, polysplenia and tetralogy of Fallot]. 61
8515166 1993
32
A case report of isolated levocardia without intracardiac anomalies associated with sick sinus syndrome. 61
8464143 1993
33
Partial situs inversus: duodenal obstruction in a neonate with isolated levocardia. 61
1469584 1992
34
Prolonged survival with isolated levocardia and situs inversus. 61
1893555 1991
35
True isolated levocardia with abdominal situs inversus. 61
2583814 1989
36
[Successful repair of isolated levocardia associated with ventricular septal defect, interrupted inferior vena cava and azygos continuation]. 61
3283391 1988
37
Isolated levocardia with interruption of infrahepatic inferior vena cava--a case report. 61
3531392 1986
38
Isolated levocardia: two cases with abdominal situs inversus, thoracic situs solitus, and normal circulation. 61
6869182 1983
39
[Isolated levocardia and corrected transposition of the great arteries in total situs inversus]. 61
6216152 1982
40
[Isolated levocardia with hepato-atrial discordance, interventricular communication and patent ductus arteriosus. Report of a case]. 61
7325845 1981
41
Successful total repair of complicated cardiac anomalies with asplenia syndrome. 61
933551 1976
42
Levocardia with visceral heterotaxy--isolated levocardia: pathologic anatomy and its clinical implications. 61
4682005 1973
43
[Isolated levocardia with reverse localization of the internal organs]. 61
5072615 1972
44
Dextrocardia with situs inversus and isolated levocardia in two male siblings. 61
4658677 1972
45
Isolated levocardia with polysplenia in an elderly woman with special reference to minor cardiac abnormalities. 61
5304141 1968
46
Ideal isolated levocardia. 61
5834189 1965
47
SITUS INVERSUS WITH LEVOCARDIA: REPORT OF A CASE WITH UNUSUAL CARDIAC MALFORMATIONS. 61
14246340 1964
48
RADIOISOTOPE SCANNING OF THE LIVER AND SPLEEN IN DEXTROCARDIA AND IN SITUS INVERSUS WITH LEVOCARDIA. 61
14119388 1964
49
[SITUS INVERSUS WITH LEVOCARDIA]. 61
14116198 1963
50
[Dilatation of the azygos vein in absence of the inferior vena cava with situs inversus with levocardia]. 61
13979637 1962

Variations for Isolated Levocardia

Expression for Isolated Levocardia

Search GEO for disease gene expression data for Isolated Levocardia.

Pathways for Isolated Levocardia

GO Terms for Isolated Levocardia

Sources for Isolated Levocardia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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