ION
MCID: ISL119
MIFTS: 30

Isolated Optic Neuritis (ION)

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Isolated Optic Neuritis

MalaCards integrated aliases for Isolated Optic Neuritis:

Name: Isolated Optic Neuritis 58
Ion 58

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases
Orphanet: 58  
Rare eye diseases


External Ids:

Orphanet 58 ORPHA499096

Summaries for Isolated Optic Neuritis

MalaCards based summary : Isolated Optic Neuritis, also known as ion, is related to brain cancer and hyperphenylalaninemia. An important gene associated with Isolated Optic Neuritis is CNP (2',3'-Cyclic Nucleotide 3' Phosphodiesterase), and among its related pathways/superpathways are Neuroscience and MECP2 and Associated Rett Syndrome. The drugs Prednisolone phosphate and Methylprednisolone have been mentioned in the context of this disorder. Affiliated tissues include eye, brain and t cells, and related phenotype is Negative genetic interaction between BLM-/- and BLM+/+.

Related Diseases for Isolated Optic Neuritis

Diseases related to Isolated Optic Neuritis via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 1587, show less)
# Related Disease Score Top Affiliating Genes
1 brain cancer 29.1 MBP CNP
2 hyperphenylalaninemia 29.0 MBP CNP
3 multiple sclerosis 28.9 MBP CNP
4 oligodendroglioma 28.6 MBP CNP
5 striatonigral degeneration 28.5 MBP CNP
6 charcot-marie-tooth disease 28.2 MBP CNP
7 chronic relapsing inflammatory optic neuropathy 11.8
8 dehydrated hereditary stomatocytosis 1 with or without pseudohyperkalemia and/or perinatal edema 11.6
9 short qt syndrome 11.5
10 renal tubular acidosis 11.5
11 mucolipidosis iv 11.5
12 familial periodic paralysis 11.5
13 pseudohypoaldosteronism, type iid 11.5
14 long qt syndrome 11.4
15 metabolic acidosis 11.4
16 alzheimer disease 11.4
17 episodic ataxia 11.4
18 secretory diarrhea 11.4
19 hyperuricemia 11.4
20 osteomalacia 11.4
21 hyperkalemic periodic paralysis 11.4
22 distal renal tubular acidosis 11.3
23 jervell and lange-nielsen syndrome 1 11.3
24 juvenile absence epilepsy 11.3
25 hereditary stomatocytosis 11.3
26 metatropic dysplasia 11.3
27 fructose-1,6-bisphosphatase deficiency 11.3
28 lichen planus 11.3
29 bartter syndrome type 4 11.3
30 gitelman syndrome 11.3
31 triiodothyronine receptor auxiliary protein 11.2
32 hyperaldosteronism, familial, type i 11.0
33 axial osteomalacia 11.0
34 cryohydrocytosis 11.0
35 jalili syndrome 11.0
36 eosinophil peroxidase deficiency 11.0
37 rh-null, regulator type 11.0
38 hyperaldosteronism, familial, type ii 11.0
39 nephrolithiasis, uric acid 11.0
40 hyperinsulinemic hypoglycemia, familial, 6 11.0
41 qt interval, variation in 11.0
42 bestrophinopathy, autosomal recessive 11.0
43 nondystrophic myotonia 11.0
44 hypotonia-speech impairment-severe cognitive delay syndrome 11.0
45 hair whorl 10.8
46 polycystic kidney disease 10.8
47 prostate cancer 10.8
48 pancreatic ductal adenocarcinoma 10.7
49 helix syndrome 10.7
50 optic neuritis 10.7
51 neuritis 10.7
52 rapidly involuting congenital hemangioma 10.7
53 endometriosis 10.6
54 cutaneous leishmaniasis 10.6
55 rheumatoid arthritis 10.5
56 follicular lymphoma 10.5
57 cystic fibrosis 10.5
58 neuroblastoma 10.5
59 dentinogenesis imperfecta type 2 10.4
60 anoxia 10.4
61 glial tumor 10.3
62 glioma 10.3
63 pertussis 10.3
64 glioblastoma multiforme 10.3
65 cholera 10.3
66 kidney disease 10.3
67 48,xyyy 10.3
68 diarrhea 10.3
69 chordoma 10.3
70 hypoxia 10.3
71 hypertension, essential 10.3
72 papillomatosis, confluent and reticulated 10.3
73 cardiac conduction defect 10.3
74 lung cancer 10.3
75 pancreatic cancer 10.3
76 chronic pain 10.3
77 cardiac arrhythmia 10.3
78 allergic hypersensitivity disease 10.3
79 ataxia and polyneuropathy, adult-onset 10.3
80 47,xyy 10.3
81 ventricular fibrillation, paroxysmal familial, 1 10.3
82 anaplastic large cell lymphoma 10.3
83 neuromyelitis optica 10.2
84 amyotrophic lateral sclerosis 1 10.2
85 migraine with or without aura 1 10.2
86 pheochromocytoma 10.2
87 adrenal gland pheochromocytoma 10.2
88 lateral sclerosis 10.2
89 ischemia 10.2
90 osteogenic sarcoma 10.2
91 brugada syndrome 10.2
92 adenoid cystic carcinoma 10.2
93 periodic paralysis 10.2
94 dental caries 10.2
95 fibrosis of extraocular muscles, congenital, 1 10.2
96 lung disease, immunodeficiency, and chromosome breakage syndrome 10.2
97 melanoma 10.2
98 bone resorption disease 10.2
99 cataract 10.2
100 mucositis 10.2
101 hepatocellular carcinoma 10.2
102 chondrosarcoma 10.2
103 adenocarcinoma 10.2
104 lung disease 10.2
105 autoimmune disease 10.2
106 muscular dystrophy 10.2
107 colorectal adenoma 10.2
108 chronic interstitial cystitis 10.2
109 renal oncocytoma 10.2
110 hepatosplenic t-cell lymphoma 10.2
111 hepatitis c virus 10.1
112 melanoma, cutaneous malignant 10 10.1
113 diphtheria 10.1
114 congestive heart failure 10.1
115 hypoglycemia 10.1
116 small cell cancer of the lung 10.1
117 epilepsy 10.1
118 myotonia 10.1
119 branchiootic syndrome 1 10.1
120 iron metabolism disease 10.1
121 atrial fibrillation 10.1
122 cardiac arrest 10.1
123 tetanus 10.1
124 anthrax disease 10.1
125 brain injury 10.1
126 ocular motor apraxia 10.1
127 heart disease 10.1
128 hypokalemia 10.1
129 posttransplant acute limbic encephalitis 10.1
130 colorectal cancer 10.1
131 inflammatory bowel disease 10.1
132 urolithiasis 10.1
133 rectum cancer 10.1
134 severe acute respiratory syndrome 10.1
135 traumatic brain injury 10.1
136 influenza 10.1
137 human immunodeficiency virus type 1 10.1
138 pulmonary hypertension 10.1
139 catecholaminergic polymorphic ventricular tachycardia 10.1
140 middle east respiratory syndrome 10.1
141 malignant hyperthermia 10.1
142 trichorhinophalangeal syndrome 10.1
143 cytokine deficiency 10.1
144 multinucleated neurons, anhydramnios, renal dysplasia, cerebellar hypoplasia, and hydranencephaly 10.1
145 pulmonary edema 10.1
146 nephrolithiasis 10.1
147 encephalopathy 10.1
148 bacterial infectious disease 10.1
149 visual epilepsy 10.1
150 hepatitis d 10.1
151 dermatitis 10.1
152 bipolar disorder 10.1
153 plague 10.1
154 prion disease 10.1
155 seizure disorder 10.1
156 argyria 10.1
157 pulmonary hypertension, primary, 3 10.1
158 cerebral artery occlusion 10.1
159 hemosiderosis 10.1
160 herpes simplex 10.1
161 spinal cord injury 10.1
162 rare hereditary hemochromatosis 10.1
163 demyelinating disease 10.0
164 huntington disease 10.0
165 melanoma, uveal 10.0
166 polykaryocytosis inducer 10.0
167 cervical cancer 10.0
168 major affective disorder 8 10.0
169 major affective disorder 9 10.0
170 lung cancer susceptibility 3 10.0
171 bone disease 10.0
172 hyperparathyroidism 10.0
173 toxic shock syndrome 10.0
174 vascular disease 10.0
175 esophageal cancer 10.0
176 hypothyroidism 10.0
177 hyperglycemia 10.0
178 amyloidosis 10.0
179 irritable bowel syndrome 10.0
180 alcohol dependence 10.0
181 phenylketonuria 10.0
182 muscular dystrophy, duchenne type 10.0
183 yemenite deaf-blind hypopigmentation syndrome 10.0
184 colitis 10.0
185 porphyria 10.0
186 gastritis 10.0
187 liver cirrhosis 10.0
188 bronchitis 10.0
189 hypokalemic periodic paralysis, type 1 10.0
190 hepatitis c 10.0
191 vaccinia 10.0
192 liver disease 10.0
193 myopathy 10.0
194 atherosclerosis susceptibility 10.0
195 atrial standstill 1 10.0
196 hand skill, relative 10.0
197 alpha/beta t-cell lymphopenia with gamma/delta t-cell expansion, severe cytomegalovirus infection, and autoimmunity 10.0
198 mucosal melanoma 10.0
199 squamous cell carcinoma 10.0
200 contact dermatitis 10.0
201 fibrosarcoma 10.0
202 brain edema 10.0
203 soft tissue sarcoma 10.0
204 syncope 10.0
205 familial long qt syndrome 10.0
206 parkinson disease, late-onset 10.0
207 dermatitis, atopic 10.0
208 meningioma, radiation-induced 10.0
209 meningioma, familial 10.0
210 ataxia, combined cerebellar and peripheral, with hearing loss and diabetes mellitus 10.0
211 spastic paraplegia, intellectual disability, nystagmus, and obesity 10.0
212 spinal meningioma 10.0
213 acute kidney failure 10.0
214 astrocytoma 10.0
215 secretory meningioma 10.0
216 lymphoplasmacyte-rich meningioma 10.0
217 end stage renal disease 10.0
218 hyperthyroidism 10.0
219 autosomal dominant polycystic kidney disease 10.0
220 heavy metal poisoning 10.0
221 febrile seizures 10.0
222 erythroleukemia, familial 10.0
223 hypercholesterolemia, familial, 1 10.0
224 proteasome-associated autoinflammatory syndrome 1 10.0
225 sudden infant death syndrome 10.0
226 aging 10.0
227 leukemia, acute myeloid 10.0
228 macular degeneration, age-related, 1 10.0
229 myocardial infarction 10.0
230 pain agnosia 10.0
231 familial hemiplegic migraine 10.0
232 dilated cardiomyopathy 10.0
233 lactic acidosis 10.0
234 skin disease 10.0
235 periodontitis 10.0
236 pik3ca-related overgrowth syndrome 10.0
237 otitis media 9.9
238 myasthenia gravis 9.9
239 malaria 9.9
240 gastric cancer 9.9
241 long qt syndrome 2 9.9
242 deficiency anemia 9.9
243 thalassemia 9.9
244 pre-eclampsia 9.9
245 sarcoma 9.9
246 goiter 9.9
247 impotence 9.9
248 allergic contact dermatitis 9.9
249 malignant glioma 9.9
250 temporal lobe epilepsy 9.9
251 spindle cell sarcoma 9.9
252 uremia 9.9
253 infertility 9.9
254 severe combined immunodeficiency 9.9
255 peptic ulcer disease 9.9
256 chronic kidney disease 9.9
257 diabetic neuropathy 9.9
258 allergic encephalomyelitis 9.9
259 depression 9.9
260 dysphagia 9.9
261 perioral myoclonia with absences 9.9
262 thyroid carcinoma 9.9
263 breast cancer 9.9
264 renal cell carcinoma, nonpapillary 9.9
265 ataxia-telangiectasia 9.9
266 osteonecrosis 9.9
267 rickets 9.9
268 gastric ulcer 9.9
269 male infertility 9.9
270 telangiectasis 9.9
271 neovascular glaucoma 9.9
272 breast adenocarcinoma 9.9
273 avian influenza 9.9
274 gastrointestinal system disease 9.9
275 retinal degeneration 9.9
276 degenerative disc disease 9.9
277 benign idiopathic neonatal seizures 9.9
278 overgrowth syndrome 9.9
279 leukoencephalopathy, hereditary diffuse, with spheroids 9.9
280 3-methylglutaconic aciduria, type iii 9.9
281 severe cutaneous adverse reaction 9.9
282 multiple sclerosis 5 9.9
283 erythema multiforme 9.9
284 optic papillitis 9.9
285 meningoencephalitis 9.9
286 lyme disease 9.9
287 iritis 9.9
288 optic nerve disease 9.9
289 myelitis 9.9
290 peripheral nervous system disease 9.9
291 herpes zoster 9.9
292 vasculitis 9.9
293 chickenpox 9.9
294 neuropathy 9.9
295 hypereosinophilic syndrome 9.9
296 herpes zoster ophthalmicus 9.9
297 erythema multiforme major 9.9
298 x-linked intellectual disability-macrocephaly-macroorchidism syndrome 9.9
299 insensitivity to pain, congenital, with anhidrosis 9.9
300 menkes disease 9.9
301 gallbladder disease 1 9.9
302 retinitis pigmentosa 18 9.9
303 gastrointestinal ulceration, recurrent, with dysfunctional platelets 9.9
304 liberfarb syndrome 9.9
305 hyperphosphatemia 9.9
306 chlamydia 9.9
307 low compliance bladder 9.9
308 hepatic coma 9.9
309 dumping syndrome 9.9
310 duodenal ulcer 9.9
311 hepatitis b 9.9
312 constipation 9.9
313 myotonia congenita 9.9
314 hemoglobinopathy 9.9
315 acute pancreatitis 9.9
316 pancreatic adenocarcinoma 9.9
317 poliomyelitis 9.9
318 osteoarthritis 9.9
319 chronic fatigue syndrome 9.9
320 diabetes mellitus 9.9
321 bladder cancer 9.9
322 diabetes mellitus, noninsulin-dependent 9.9
323 keratitis, hereditary 9.9
324 lithium transport 9.9
325 wilson disease 9.9
326 asthma 9.9
327 chudley-mccullough syndrome 9.9
328 major depressive disorder 9.9
329 intraocular pressure quantitative trait locus 9.9
330 microvascular complications of diabetes 5 9.9
331 atrioventricular block 9.9
332 generalized epilepsy with febrile seizures plus 9.9
333 respiratory failure 9.9
334 secondary hyperparathyroidism 9.9
335 acute cystitis 9.9
336 sick sinus syndrome 9.9
337 pulmonary tuberculosis 9.9
338 lysosomal storage disease 9.9
339 insulinoma 9.9
340 scrapie 9.9
341 retinal disease 9.9
342 hemolytic anemia 9.9
343 adenoma 9.9
344 allergic asthma 9.9
345 alopecia 9.9
346 beryllium disease 9.9
347 chromosomal triplication 9.9
348 familial hypertension 9.9
349 haemophilus influenzae 9.9
350 chronic beryllium disease 9.9
351 meniere disease 9.8
352 episodic ataxia, type 1 9.8
353 nephrolithiasis, calcium oxalate 9.8
354 paramyotonia congenita of von eulenburg 9.8
355 down syndrome 9.8
356 methane production 9.8
357 retinitis pigmentosa 9.8
358 meester-loeys syndrome 9.8
359 sickle cell anemia 9.8
360 pulmonary disease, chronic obstructive 9.8
361 nasopharyngeal carcinoma 9.8
362 kala-azar 1 9.8
363 dengue virus 9.8
364 autosomal recessive disease 9.8
365 sinoatrial node disease 9.8
366 lymphoma 9.8
367 osteomyelitis 9.8
368 iron deficiency anemia 9.8
369 hypertrophic cardiomyopathy 9.8
370 dysentery 9.8
371 eclampsia 9.8
372 mental depression 9.8
373 status epilepticus 9.8
374 hyperinsulinism 9.8
375 benign mesothelioma 9.8
376 glomerulonephritis 9.8
377 mood disorder 9.8
378 pulmonary fibrosis 9.8
379 pseudohypoaldosteronism 9.8
380 pancreatitis 9.8
381 ulcerative colitis 9.8
382 myeloid leukemia 9.8
383 leishmaniasis 9.8
384 pathologic nystagmus 9.8
385 disseminated infection with mycobacterium avium complex 9.8
386 stenotrophomonas maltophilia infection 9.8
387 genetic epilepsy with febrile seizures plus 9.8
388 periodic paralyses 9.8
389 neurofibromatosis, type ii 9.8
390 arteries, anomalies of 9.8
391 optic atrophy with or without deafness, ophthalmoplegia, myopathy, ataxia, and neuropathy 9.8
392 metaphyseal chondrodysplasia, schmid type 9.8
393 smith-lemli-opitz syndrome 9.8
394 insulin-like growth factor i 9.8
395 opitz gbbb syndrome, type i 9.8
396 anemia, x-linked, with or without neutropenia and/or platelet abnormalities 9.8
397 epilepsy, idiopathic generalized 9.8
398 homocysteinemia 9.8
399 creatinine clearance quantitative trait locus 9.8
400 allergic rhinitis 9.8
401 anxiety 9.8
402 microvascular complications of diabetes 3 9.8
403 microvascular complications of diabetes 4 9.8
404 microvascular complications of diabetes 6 9.8
405 microvascular complications of diabetes 7 9.8
406 scoliosis 9.8
407 mucolipidosis 9.8
408 sensorineural hearing loss 9.8
409 neuroretinitis 9.8
410 arteriovenous malformation 9.8
411 nephrocalcinosis 9.8
412 gout 9.8
413 hepatic encephalopathy 9.8
414 polyneuropathy 9.8
415 autosomal dominant cerebellar ataxia 9.8
416 root resorption 9.8
417 gastroenteritis 9.8
418 colon adenocarcinoma 9.8
419 rhabdomyosarcoma 9.8
420 retinitis 9.8
421 congenital myasthenic syndrome 9.8
422 rhinitis 9.8
423 mucoepidermoid carcinoma 9.8
424 acquired immunodeficiency syndrome 9.8
425 measles 9.8
426 acute myocardial infarction 9.8
427 fatty liver disease 9.8
428 encephalitis 9.8
429 stomatitis 9.8
430 yellow fever 9.8
431 pituitary tumors 9.8
432 cerebrofacial arteriovenous metameric syndrome 9.8
433 episodic ataxia, type 2 9.8
434 central core disease of muscle 9.8
435 creutzfeldt-jakob disease 9.8
436 osteoporosis 9.8
437 ovarian cancer 9.8
438 pulmonary hypertension, primary, 1 9.8
439 suppressor of tumorigenicity 3 9.8
440 hemochromatosis, type 1 9.8
441 periodontitis, chronic 9.8
442 osteoporosis and oculocutaneous hypopigmentation syndrome 9.8
443 coronary heart disease 1 9.8
444 leukemia, acute lymphoblastic 3 9.8
445 cholangiocarcinoma 9.8
446 carbonic anhydrase va deficiency, hyperammonemia due to 9.8
447 chorea, childhood-onset, with psychomotor retardation 9.8
448 hyperlipoproteinemia, type iii 9.8
449 lipoprotein quantitative trait locus 9.8
450 angina pectoris 9.8
451 lambert-eaton myasthenic syndrome 9.8
452 arrhythmogenic right ventricular cardiomyopathy 9.8
453 colorectal adenocarcinoma 9.8
454 salivary gland carcinoma 9.8
455 migraine with aura 9.8
456 sleeping sickness 9.8
457 trypanosomiasis 9.8
458 glucose intolerance 9.8
459 mastitis 9.8
460 neutropenia 9.8
461 leukemia 9.8
462 choreatic disease 9.8
463 prostatitis 9.8
464 methylmalonic acidemia 9.8
465 cystitis 9.8
466 bone cancer 9.8
467 early myoclonic encephalopathy 9.8
468 skin carcinoma 9.8
469 duodenogastric reflux 9.8
470 bartter disease 9.8
471 intrahepatic cholangiocarcinoma 9.8
472 intestinal disease 9.8
473 dystonia 9.8
474 eye disease 9.8
475 inherited metabolic disorder 9.8
476 myocarditis 9.8
477 neurofibromatosis 9.8
478 peroxisomal disease 9.8
479 gas gangrene 9.8
480 catsper-related male infertility 9.8
481 congenital disorders of n-linked glycosylation and multiple pathway 9.8
482 sickle cell disease 9.8
483 candida glabrata 9.8
484 mercury poisoning 9.8
485 acute liver failure 9.8
486 rare tumor 9.8
487 leukemia, chronic lymphocytic 9.7
488 schizophrenia 9.7
489 spinocerebellar ataxia 6 9.7
490 urate oxidase, pseudogene 9.7
491 autism 9.7
492 lymphoma, hodgkin, classic 9.7
493 thymoma, familial 9.7
494 fragile x syndrome 9.7
495 suppression of tumorigenicity 12 9.7
496 stroke, ischemic 9.7
497 cataract 3, multiple types 9.7
498 long qt syndrome 3 9.7
499 huntington disease-like 3 9.7
500 epileptic encephalopathy, early infantile, 6 9.7
501 endometrial cancer 9.7
502 bone mineral density quantitative trait locus 8 9.7
503 ewing sarcoma 9.7
504 diabetes mellitus, ketosis-prone 9.7
505 hearing loss, noise-induced 9.7
506 leukemia, acute lymphoblastic 9.7
507 polycystic kidney disease 2 with or without polycystic liver disease 9.7
508 bone mineral density quantitative trait locus 15 9.7
509 joint laxity, short stature, and myopia 9.7
510 peripheral vascular disease 9.7
511 exanthem 9.7
512 peripheral artery disease 9.7
513 oral squamous cell carcinoma 9.7
514 stuttering 9.7
515 autosomal dominant nocturnal frontal lobe epilepsy 9.7
516 covid-19 9.7
517 cholelithiasis 9.7
518 hydrocephalus 9.7
519 primary hyperparathyroidism 9.7
520 pyelonephritis 9.7
521 myopia 9.7
522 nephrotic syndrome 9.7
523 renal osteodystrophy 9.7
524 uveitis 9.7
525 achromatopsia 9.7
526 candidiasis 9.7
527 endogenous depression 9.7
528 arteriosclerosis 9.7
529 retinal vascular disease 9.7
530 enamel erosion 9.7
531 kidney cancer 9.7
532 gingivitis 9.7
533 thymoma 9.7
534 purpura 9.7
535 liposarcoma 9.7
536 bacterial vaginosis 9.7
537 olfactory neuroblastoma 9.7
538 cervical adenocarcinoma 9.7
539 gastric adenocarcinoma 9.7
540 arthropathy 9.7
541 mouth disease 9.7
542 heart valve disease 9.7
543 hepatitis e 9.7
544 movement disease 9.7
545 thyroid gland disease 9.7
546 panic disorder 9.7
547 fibromyalgia 9.7
548 muscular atrophy 9.7
549 peritonitis 9.7
550 bacterial pneumonia 9.7
551 rubella 9.7
552 homocystinuria 9.7
553 cholangitis 9.7
554 meningitis 9.7
555 bronchiectasis 9.7
556 hemophilia 9.7
557 keloid disorder 9.7
558 myotonic dystrophy 9.7
559 acute mountain sickness 9.7
560 aminoaciduria 9.7
561 mast cell activation syndrome 9.7
562 oral cancer 9.7
563 pediatric acute-onset neuropsychiatric syndrome 9.7
564 aneurysm 9.7
565 head injury 9.7
566 tremor 9.7
567 avascular necrosis 9.7
568 cardiogenic shock 9.7
569 glomerular disease 9.7
570 seizures, benign familial neonatal, 1 9.6
571 epithelial recurrent erosion dystrophy 9.6
572 major affective disorder 1 9.6
573 hypertriglyceridemia, familial 9.6
574 lacrimal duct defect 9.6
575 antigen defined by monoclonal antibody aj9 9.6
576 paroxysmal extreme pain disorder 9.6
577 pancreatitis, hereditary 9.6
578 andersen cardiodysrhythmic periodic paralysis 9.6
579 porphyria, acute intermittent 9.6
580 porphyria cutanea tarda 9.6
581 retinal detachment 9.6
582 sarcoidosis 1 9.6
583 schistosoma mansoni infection, susceptibility/ 9.6
584 neural tube defects 9.6
585 trigeminal neuralgia 9.6
586 anemia, hypochromic microcytic, with iron overload 1 9.6
587 celiac disease 1 9.6
588 diabetes mellitus, type i 9.6
589 enterocolitis 9.6
590 hutterite cerebroosteonephrodysplasia syndrome 9.6
591 immune deficiency disease 9.6
592 maple syrup urine disease 9.6
593 epilepsy, myoclonic juvenile 9.6
594 graves disease 1 9.6
595 squamous cell carcinoma, head and neck 9.6
596 body mass index quantitative trait locus 11 9.6
597 hemophilia a 9.6
598 helicobacter pylori infection 9.6
599 timothy syndrome 9.6
600 autoimmune lymphoproliferative syndrome 9.6
601 huntington disease-like 2 9.6
602 amyotrophic lateral sclerosis 3 9.6
603 anorexia nervosa 9.6
604 myotonia, potassium-aggravated 9.6
605 pseudohyperkalemia, familial, 2, due to red cell leak 9.6
606 west nile virus 9.6
607 hamamy syndrome 9.6
608 ectodermal dysplasia-syndactyly syndrome 2 9.6
609 barrett esophagus 9.6
610 pulmonary hypertension, primary, 4 9.6
611 alacrima, achalasia, and mental retardation syndrome 9.6
612 pachyonychia congenita 3 9.6
613 seizures, scoliosis, and macrocephaly/microcephaly syndrome 9.6
614 hypertrophic scars 9.6
615 angiosarcoma 9.6
616 hypophosphatemia 9.6
617 foodborne botulism 9.6
618 familial adenomatous polyposis 9.6
619 variola major 9.6
620 hypochromic microcytic anemia 9.6
621 small cell carcinoma 9.6
622 secondary progressive multiple sclerosis 9.6
623 sleep apnea 9.6
624 autism spectrum disorder 9.6
625 metal allergy 9.6
626 non-alcoholic fatty liver disease 9.6
627 mumps 9.6
628 leukodystrophy 9.6
629 short bowel syndrome 9.6
630 dissociative disorder 9.6
631 hypoparathyroidism 9.6
632 rabies 9.6
633 esophagitis 9.6
634 chagas disease 9.6
635 retinal ischemia 9.6
636 hereditary spherocytosis 9.6
637 dementia 9.6
638 severe pre-eclampsia 9.6
639 obstructive jaundice 9.6
640 squamous cell papilloma 9.6
641 schistosomiasis 9.6
642 plasmodium falciparum malaria 9.6
643 rheumatic fever 9.6
644 ocular melanoma 9.6
645 malignant fibrous histiocytoma 9.6
646 leptospirosis 9.6
647 acromegaly 9.6
648 papilloma 9.6
649 transitional cell carcinoma 9.6
650 bilirubin metabolic disorder 9.6
651 hairy cell leukemia 9.6
652 cervix carcinoma 9.6
653 primary hyperoxaluria 9.6
654 grade iii astrocytoma 9.6
655 acute porphyria 9.6
656 mastocytosis 9.6
657 cervical squamous cell carcinoma 9.6
658 vaginal discharge 9.6
659 multidrug-resistant tuberculosis 9.6
660 systemic scleroderma 9.6
661 pustulosis of palm and sole 9.6
662 neuromuscular disease 9.6
663 fibrous histiocytoma 9.6
664 sleep disorder 9.6
665 hemoglobin d disease 9.6
666 b-cell lymphoma 9.6
667 placenta disease 9.6
668 intestinal obstruction 9.6
669 night blindness 9.6
670 monocytic leukemia 9.6
671 in situ carcinoma 9.6
672 smallpox 9.6
673 crohn's disease 9.6
674 psoriasis 9.6
675 macroglobulinemia 9.6
676 ocular hypertension 9.6
677 keratoconjunctivitis 9.6
678 pulmonary embolism 9.6
679 hemorrhoid 9.6
680 cocaine dependence 9.6
681 isolated methylmalonic acidemia 9.6
682 aminoacidopathies 9.6
683 familial primary hypomagnesemia with hypercalciuria and nephrocalcinosis 9.6
684 myalgic encephalomyelitis/chronic fatigue syndrome 9.6
685 radiation induced cancer 9.6
686 opioid addiction 9.6
687 cerebral aneurysms 9.6
688 hypotonia 9.6
689 paresthesia 9.6
690 audiogenic seizures 9.6
691 paroxysmal dyskinesia 9.6
692 idiopathic hypercalciuria 9.6
693 osteonecrosis of the jaw 9.6
694 premature aging 9.6
695 thyroid tumor 9.6
696 niemann-pick disease, type a 9.6 MBP CNP
697 angelman syndrome 9.6
698 spondyloarthropathy 1 9.6
699 gastroesophageal reflux 9.6
700 blepharophimosis, ptosis, and epicanthus inversus 9.6
701 progressive familial heart block, type ia 9.6
702 cleft palate, isolated 9.6
703 macular dystrophy, vitelliform, 2 9.6
704 mesothelioma, malignant 9.6
705 multicentric carpotarsal osteolysis syndrome 9.6
706 phosphoglycoprotein 1 9.6
707 hutchinson-gilford progeria syndrome 9.6
708 pulmonary fibrosis, idiopathic 9.6
709 renal tubular acidosis, proximal 9.6
710 dowling-degos disease 1 9.6
711 retinoblastoma 9.6
712 scoliosis, isolated 1 9.6
713 overhydrated hereditary stomatocytosis 9.6
714 thyroid cancer, nonmedullary, 1 9.6
715 tracheoesophageal fistula with or without esophageal atresia 9.6
716 tuberous sclerosis 1 9.6
717 varicose veins 9.6
718 long qt syndrome 1 9.6
719 vitiligo-associated multiple autoimmune disease susceptibility 6 9.6
720 volvulus of midgut 9.6
721 acyl-coa dehydrogenase, medium-chain, deficiency of 9.6
722 aspartylglucosaminuria 9.6
723 friedreich ataxia 9.6
724 diarrhea 2, with microvillus atrophy 9.6
725 myeloma, multiple 9.6
726 leigh syndrome 9.6
727 orotic aciduria 9.6
728 subacute sclerosing panencephalitis 9.6
729 scott syndrome 9.6
730 sjogren syndrome 9.6
731 vas deferens, congenital bilateral aplasia of 9.6
732 lesch-nyhan syndrome 9.6
733 hemophilia b 9.6
734 paine syndrome 9.6
735 rett syndrome 9.6
736 epilepsy, nocturnal frontal lobe, 1 9.6
737 wilms tumor 5 9.6
738 paragangliomas 2 9.6
739 body mass index quantitative trait locus 9 9.6
740 amyotrophic lateral sclerosis 5, juvenile 9.6
741 astigmatism 9.6
742 body mass index quantitative trait locus 8 9.6
743 progressive familial heart block, type ib 9.6
744 hypertension, early-onset, autosomal dominant, with severe exacerbation in pregnancy 9.6
745 diamond-blackfan anemia 2 9.6
746 alveolar soft part sarcoma 9.6
747 vitiligo-associated multiple autoimmune disease susceptibility 1 9.6
748 spermatogenic failure 3 9.6
749 osteofibrous dysplasia 9.6
750 body mass index quantitative trait locus 4 9.6
751 body mass index quantitative trait locus 10 9.6
752 spastic paraplegia, ataxia, and mental retardation 9.6
753 epilepsy, juvenile absence 1 9.6
754 body mass index quantitative trait locus 7 9.6
755 potocki-lupski syndrome 9.6
756 pitt-hopkins syndrome 9.6
757 microphthalmia, syndromic 10 9.6
758 major affective disorder 5 9.6
759 major affective disorder 6 9.6
760 alopecia, neurologic defects, and endocrinopathy syndrome 9.6
761 body mass index quantitative trait locus 12 9.6
762 body mass index quantitative trait locus 14 9.6
763 leukemia, acute lymphoblastic 2 9.6
764 hypotrichosis and recurrent skin vesicles 9.6
765 thyrotoxic periodic paralysis 2 9.6
766 fatty liver disease, nonalcoholic 1 9.6
767 bile acid malabsorption, primary 9.6
768 mononeuropathy of the median nerve, mild 9.6
769 megalencephalic leukoencephalopathy with subcortical cysts 2a 9.6
770 beta-thalassemia 9.6
771 muscle hypertrophy 9.6
772 pseudohypoaldosteronism, type iie 9.6
773 hemorrhage, intracerebral 9.6
774 hypogonadotropic hypogonadism 16 with or without anosmia 9.6
775 retinal dystrophy, iris coloboma, and comedogenic acne syndrome 9.6
776 steel syndrome 9.6
777 body mass index quantitative trait locus 18 9.6
778 craniosynostosis 5 9.6
779 episodic pain syndrome, familial, 3 9.6
780 autoimmune lymphoproliferative syndrome, type v 9.6
781 alkuraya-kucinskas syndrome 9.6
782 body mass index quantitative trait locus 19 9.6
783 encephalopathy, progressive, early-onset, with episodic rhabdomyolysis 9.6
784 body mass index quantitative trait locus 20 9.6
785 megabladder, congenital 9.6
786 chronic ulcer of skin 9.6
787 congenital chloride diarrhea 9.6
788 autoimmune uveitis 9.6
789 chikungunya 9.6
790 congenital stationary night blindness 9.6
791 distal arthrogryposis 9.6
792 familial atrial fibrillation 9.6
793 chorioamnionitis 9.6
794 diffuse large b-cell lymphoma 9.6
795 cone dystrophy 9.6
796 chronic venous insufficiency 9.6
797 tongue squamous cell carcinoma 9.6
798 fibroma 9.6
799 autosomal recessive cerebellar ataxia 9.6
800 ductal carcinoma in situ 9.6
801 clostridium difficile colitis 9.6
802 idiopathic scoliosis 9.6
803 gallbladder disease 9.6
804 hyperekplexia 9.6
805 familial hypocalciuric hypercalcemia 9.6
806 salmonellosis 9.6
807 thrombosis 9.6
808 desmoid tumor 9.6
809 non-alcoholic steatohepatitis 9.6
810 bone sarcoma 9.6
811 progressive familial heart block 9.6
812 venous insufficiency 9.6
813 aortic atherosclerosis 9.6
814 siderosis 9.6
815 microphthalmia 9.6
816 open-angle glaucoma 9.6
817 renal hypertension 9.6
818 methemoglobinemia 9.6
819 filariasis 9.6
820 microcephaly 9.6
821 tooth disease 9.6
822 amnestic disorder 9.6
823 leech infestation 9.6
824 vitamin k deficiency bleeding 9.6
825 corneal neovascularization 9.6
826 fuchs' endothelial dystrophy 9.6
827 chondrocalcinosis 9.6
828 listeriosis 9.6
829 onchocerciasis 9.6
830 neonatal diabetes mellitus 9.6
831 coronary artery vasospasm 9.6
832 inflammatory spondylopathy 9.6
833 otosclerosis 9.6
834 dengue disease 9.6
835 filarial elephantiasis 9.6
836 primary biliary cirrhosis 9.6
837 retroperitoneal sarcoma 9.6
838 graves' disease 9.6
839 bronchopneumonia 9.6
840 acute kidney tubular necrosis 9.6
841 keratoconjunctivitis sicca 9.6
842 focal segmental glomerulosclerosis 9.6
843 klebsiella pneumonia 9.6
844 hyperinsulinemic hypoglycemia 9.6
845 color blindness 9.6
846 tuberous sclerosis 9.6
847 osteopetrosis 9.6
848 kwashiorkor 9.6
849 cholestasis 9.6
850 biliary atresia 9.6
851 mature cataract 9.6
852 bacteriuria 9.6
853 frozen shoulder 9.6
854 thrombocytopenia 9.6
855 keratosis 9.6
856 retinal vein occlusion 9.6
857 cryptosporidiosis 9.6
858 cholecystitis 9.6
859 enthesopathy 9.6
860 enamel caries 9.6
861 vaginitis 9.6
862 relapsing-remitting multiple sclerosis 9.6
863 sensory peripheral neuropathy 9.6
864 basal cell carcinoma 9.6
865 corneal dystrophy 9.6
866 newcastle disease 9.6
867 inner ear disease 9.6
868 iga glomerulonephritis 9.6
869 substance abuse 9.6
870 food allergy 9.6
871 gliosarcoma 9.6
872 proctitis 9.6
873 lipid metabolism disorder 9.6
874 complex regional pain syndrome 9.6
875 chronic granulomatous disease 9.6
876 teratoma 9.6
877 embryonal carcinoma 9.6
878 gm1 gangliosidosis 9.6
879 mammary paget's disease 9.6
880 choriocarcinoma 9.6
881 lung squamous cell carcinoma 9.6
882 biliary dyskinesia 9.6
883 radiculopathy 9.6
884 skull base meningioma 9.6
885 macular retinal edema 9.6
886 clear cell renal cell carcinoma 9.6
887 familial retinoblastoma 9.6
888 prostate disease 9.6
889 benign ependymoma 9.6
890 neurotic disorder 9.6
891 middle ear disease 9.6
892 urinary tract obstruction 9.6
893 cellular ependymoma 9.6
894 hemoglobinuria 9.6
895 esophageal disease 9.6
896 conjunctivitis 9.6
897 spondylitis 9.6
898 cerebrovascular disease 9.6
899 pancreatic cholera 9.6
900 premenstrual tension 9.6
901 carotid artery occlusion 9.6
902 cocaine abuse 9.6
903 learning disability 9.6
904 atrophic gastritis 9.6
905 zellweger syndrome 9.6
906 visceral leishmaniasis 9.6
907 erythromelalgia 9.6
908 tyrosinemia 9.6
909 diabetes insipidus 9.6
910 senile cataract 9.6
911 myocardial stunning 9.6
912 limb-girdle muscular dystrophy 9.6
913 dystrophinopathies 9.6
914 medium-chain acyl-coenzyme a dehydrogenase deficiency 9.6
915 unc80 deficiency 9.6
916 aids dementia complex 9.6
917 anaplastic oligoastrocytoma 9.6
918 complete androgen insensitivity syndrome 9.6
919 congenital hydrocephalus 9.6
920 gangliosidosis 9.6
921 hemangioendothelioma 9.6
922 limbic encephalitis 9.6
923 mycobacterium marinum 9.6
924 nephrogenic systemic fibrosis 9.6
925 splenomegaly 9.6
926 thyrotoxic periodic paralysis 9.6
927 tuberculous meningitis 9.6
928 color vision deficiency 9.6
929 autonomic dysfunction 9.6
930 dysautonomia 9.6
931 familial periodic paralyses 9.6
932 headache 9.6
933 paroxysmal dystonia 9.6
934 ciliopathy 9.6
935 combined pulmonary fibrosis-emphysema syndrome 9.6
936 congenital amyoplasia 9.6
937 cebpe-associated autoinflammation-immunodeficiency-neutrophil dysfunction syndrome 9.6
938 familial short qt syndrome 9.6
939 cocaine intoxication 9.6
940 myoclonic epilepsy of infancy 9.6
941 fungal keratitis 9.6
942 uremic pruritus 9.6
943 vitreoretinopathy 9.6
944 pelizaeus-merzbacher disease 9.5 MBP CNP
945 aortic aneurysm, familial abdominal, 1 9.4
946 cerebral amyloid angiopathy, cst3-related 9.4
947 amyloidosis, hereditary, transthyretin-related 9.4
948 anorectal anomalies 9.4
949 arthrogryposis, distal, type 5 9.4
950 machado-joseph disease 9.4
951 biliary cirrhosis, primary, 1 9.4
952 burkitt lymphoma 9.4
953 carcinoid tumors, intestinal 9.4
954 cardiomyopathy, familial hypertrophic, 2 9.4
955 hypercarotenemia and vitamin a deficiency, autosomal dominant 9.4
956 paroxysmal nonkinesigenic dyskinesia 1 9.4
957 coarctation of aorta 9.4
958 craniofacial-deafness-hand syndrome 9.4
959 danubian endemic familial nephropathy 9.4
960 dermal ridges-off-the-end 9.4
961 diabetes insipidus, nephrogenic, autosomal 9.4
962 discrimination, two-point, reduction in 9.4
963 episodic kinesigenic dyskinesia 1 9.4
964 elliptocytosis 2 9.4
965 exudative vitreoretinopathy 1 9.4
966 corneal dystrophy, fuchs endothelial, 1 9.4
967 glioma susceptibility 1 9.4
968 hyperglycinuria 9.4
969 hashimoto thyroiditis 9.4
970 hemifacial spasm, familial 9.4
971 hernia, hiatus 9.4
972 developmental dysplasia of the hip 1 9.4
973 hypercalciuria, absorptive, 2 9.4
974 hypercalcemia, infantile, 1 9.4
975 hyperpigmentation with or without hypopigmentation, familial progressive 9.4
976 hypocalciuric hypercalcemia, familial, type i 9.4
977 hypoparathyroidism, familial isolated, 1 9.4
978 multiple system atrophy 1 9.4
979 ige responsiveness, atopic 9.4
980 lipomatosis, multiple 9.4
981 systemic lupus erythematosus 9.4
982 marfan syndrome 9.4
983 visceral myopathy 9.4
984 microphthalmia, isolated, with cataract 1 9.4
985 antigen defined by monoclonal antibody t87 9.4
986 motion sickness 9.4
987 myopia 2, autosomal dominant 9.4
988 myotonia congenita, autosomal dominant 9.4
989 nail-patella syndrome 9.4
990 renal failure, progressive, with hypertension 9.4
991 neurofibromatosis, type i 9.4
992 neutrophil migration 9.4
993 sick sinus syndrome 2 9.4
994 spinocerebellar ataxia 1 9.4
995 omodysplasia 2 9.4
996 optic atrophy 1 9.4
997 parastremmatic dwarfism 9.4
998 benign chronic pemphigus 9.4
999 prolidase deficiency 9.4
1000 normokalemic periodic paralysis 9.4
1001 pick disease of brain 9.4
1002 platelet adenylate cyclase activity 9.4
1003 platelet membrane fluidity 9.4
1004 polycystic kidney disease 1 with or without polycystic liver disease 9.4
1005 greig cephalopolysyndactyly syndrome 9.4
1006 liddle syndrome 1 9.4
1007 red cell phospholipid defect with hemolysis 9.4
1008 renal tubular acidosis, distal, autosomal dominant 9.4
1009 spondyloepiphyseal dysplasia, maroteaux type 9.4
1010 spondyloepimetaphyseal dysplasia, strudwick type 9.4
1011 spondylometaphyseal dysplasia, kozlowski type 9.4
1012 torticollis 9.4
1013 bladder dysfunction, autonomic, with impaired pupillary reflex and secondary cakut 9.4
1014 vasculitis, lymphocytic, nodular 9.4
1015 vitreoretinal degeneration, snowflake type 9.4
1016 vitreoretinopathy, neovascular inflammatory 9.4
1017 wolff-parkinson-white syndrome 9.4
1018 abetalipoproteinemia 9.4
1019 acrocallosal syndrome 9.4
1020 acrodermatitis enteropathica, zinc-deficiency type 9.4
1021 adrenal hyperplasia, congenital, due to 21-hydroxylase deficiency 9.4
1022 alpha-methylacetoacetic aciduria 9.4
1023 anemia, autoimmune hemolytic 9.4
1024 iron-refractory iron deficiency anemia 9.4
1025 anencephaly 9.4
1026 argininemia 9.4
1027 argininosuccinic aciduria 9.4
1028 carnitine deficiency, systemic primary 9.4
1029 cerebrotendinous xanthomatosis 9.4
1030 charge syndrome 9.4
1031 corneal dystrophy, band-shaped 9.4
1032 corneal endothelial dystrophy 9.4
1033 cystathioninuria 9.4
1034 wolfram syndrome 1 9.4
1035 dibasic amino aciduria i 9.4
1036 duodenal atresia 9.4
1037 neuropathy, hereditary sensory and autonomic, type iii 9.4
1038 schopf-schulz-passarge syndrome 9.4
1039 fanconi anemia, complementation group a 9.4
1040 fanconi-bickel syndrome 9.4
1041 fucosidosis 9.4
1042 hydrocephalus due to congenital stenosis of aqueduct of sylvius 9.4
1043 hyperornithinemia-hyperammonemia-homocitrullinuria syndrome 9.4
1044 hyperparathyroidism, neonatal severe 9.4
1045 hypoascorbemia 9.4
1046 hypokalemic alkalosis, familial, with specific renal tubulopathy 9.4
1047 isovaleric acidemia 9.4
1048 jumping frenchmen of maine 9.4
1049 krabbe disease 9.4
1050 laryngoonychocutaneous syndrome 9.4
1051 chylomicron retention disease 9.4
1052 megacystis-microcolon-intestinal hypoperistalsis syndrome 9.4
1053 metachromatic leukodystrophy 9.4
1054 spondylometaphyseal dysplasia, sedaghatian type 9.4
1055 microcolon 9.4
1056 muscular dystrophy, limb-girdle, autosomal recessive 2 9.4
1057 myopathy, congenital 9.4
1058 myotonia congenita, autosomal recessive 9.4
1059 omodysplasia 1 9.4
1060 hyperoxaluria, primary, type i 9.4
1061 papilloma of choroid plexus 9.4
1062 polycystic kidney disease 4 with or without polycystic liver disease 9.4
1063 porphyria, congenital erythropoietic 9.4
1064 pseudoxanthoma elasticum 9.4
1065 refsum disease, classic 9.4
1066 perlman syndrome 9.4
1067 enhanced s-cone syndrome 9.4
1068 rheumatic fever-related antigen 9.4
1069 senile plaque formation 9.4
1070 sialuria 9.4
1071 multiple sulfatase deficiency 9.4
1072 thrombotic thrombocytopenic purpura, hereditary 9.4
1073 tyrosinemia, type ii 9.4
1074 tyrosinemia, type i 9.4
1075 werner syndrome 9.4
1076 xeroderma pigmentosum, complementation group a 9.4
1077 xeroderma pigmentosum, variant type 9.4
1078 dent disease 1 9.4
1079 adrenoleukodystrophy 9.4
1080 muscular dystrophy, becker type 9.4
1081 allan-herndon-dudley syndrome 9.4
1082 tn polyagglutination syndrome 9.4
1083 sarcoma, synovial 9.4
1084 mcleod syndrome 9.4
1085 anemia, nonspherocytic hemolytic, due to g6pd deficiency 9.4
1086 mend syndrome 9.4
1087 alport syndrome 1, x-linked 9.4
1088 fabry disease 9.4
1089 arts syndrome 9.4
1090 tubulin, beta 9.4
1091 glycerol kinase deficiency 9.4
1092 norrie disease 9.4
1093 ouabain resistance 9.4
1094 androgen insensitivity, partial 9.4
1095 spastic paraplegia 2, x-linked 9.4
1096 cyclic vomiting syndrome 9.4
1097 kearns-sayre syndrome 9.4
1098 neuropathy, ataxia, and retinitis pigmentosa 9.4
1099 frontotemporal dementia 9.4
1100 hypocalciuric hypercalcemia, familial, type iii 9.4
1101 brody myopathy 9.4
1102 supranuclear palsy, progressive, 1 9.4
1103 cerebellar ataxia, areflexia, pes cavus, optic atrophy, and sensorineural hearing loss 9.4
1104 myasthenic syndrome, congenital, 1a, slow-channel 9.4
1105 hyperinsulinemic hypoglycemia, familial, 2 9.4
1106 hypomagnesemia 1, intestinal 9.4
1107 xanthomatosis 9.4
1108 migraine, familial hemiplegic, 2 9.4
1109 bartter syndrome, type 4a, neonatal, with sensorineural deafness 9.4
1110 leukoregulin 9.4
1111 microvascular complications of diabetes 1 9.4
1112 megalencephalic leukoencephalopathy with subcortical cysts 1 9.4
1113 orthostatic intolerance 9.4
1114 lymphoma, non-hodgkin, familial 9.4
1115 cataract 26, multiple types 9.4
1116 myasthenic syndrome, congenital, 4a, slow-channel 9.4
1117 maturity-onset diabetes of the young 9.4
1118 body mass index quantitative trait locus 1 9.4
1119 spongiform encephalopathy with neuropsychiatric features 9.4
1120 cinca syndrome 9.4
1121 muscular dystrophy-dystroglycanopathy , type c, 5 9.4
1122 epilepsy, partial, with pericentral spikes 9.4
1123 resting heart rate, variation in 9.4
1124 niemann-pick disease, type c2 9.4
1125 febrile seizures, familial, 8 9.4
1126 seizures, benign familial infantile, 3 9.4
1127 dermatofibrosarcoma protuberans 9.4
1128 mycobacterium tuberculosis 1 9.4
1129 ovarian hyperstimulation syndrome 9.4
1130 hermansky-pudlak syndrome 2 9.4
1131 myasthenic syndrome, congenital, 1b, fast-channel 9.4
1132 premature ovarian failure 3 9.4
1133 rhabdoid tumor predisposition syndrome 1 9.4
1134 nanophthalmos 2 9.4
1135 short qt syndrome 1 9.4
1136 hyperinsulinemic hypoglycemia, familial, 5 9.4
1137 hyperinsulinemic hypoglycemia, familial, 4 9.4
1138 aicardi-goutieres syndrome 3 9.4
1139 cinnamon odor, pleasantness of 9.4
1140 cavitary optic disc anomalies 9.4
1141 long qt syndrome 9 9.4
1142 colorectal cancer 7 9.4
1143 acute promyelocytic leukemia 9.4
1144 breast-ovarian cancer, familial 2 9.4
1145 microvascular complications of diabetes 2 9.4
1146 long qt syndrome 12 9.4
1147 spermatogenic failure 7 9.4
1148 biliary cirrhosis, primary, 2 9.4
1149 liver failure, infantile, transient 9.4
1150 night blindness, congenital stationary, type 1c 9.4
1151 diarrhea 5, with tufting enteropathy, congenital 9.4
1152 hypokalemic periodic paralysis, type 2 9.4
1153 hyperoxaluria, primary, type iii 9.4
1154 brachyolmia type 2 9.4
1155 long qt syndrome 5 9.4
1156 nestor-guillermo progeria syndrome 9.4
1157 aspergillosis 9.4
1158 pyruvate dehydrogenase e1-beta deficiency 9.4
1159 myelodysplastic syndrome 9.4
1160 palmoplantar keratoderma, mutilating, with periorificial keratotic plaques 9.4
1161 human herpesvirus 8 9.4
1162 dystonia 23 9.4
1163 epidermolysis bullosa, nonspecific, autosomal recessive 9.4
1164 dystonia 24 9.4
1165 congenital short bowel syndrome 9.4
1166 cardiofaciocutaneous syndrome 2 9.4
1167 pulmonary hypertension, primary, 2 9.4
1168 hypotonia, infantile, with psychomotor retardation and characteristic facies 1 9.4
1169 hyperprolactinemia 9.4
1170 melioidosis 9.4
1171 sacral agenesis with vertebral anomalies 9.4
1172 sting-associated vasculopathy, infantile-onset 9.4
1173 congenital contractures of the limbs and face, hypotonia, and developmental delay 9.4
1174 chops syndrome 9.4
1175 trichothiodystrophy 3, photosensitive 9.4
1176 b-cell expansion with nfkb and t-cell anergy 9.4
1177 hypotonia, infantile, with psychomotor retardation and characteristic facies 2 9.4
1178 striatal degeneration, autosomal dominant 2 9.4
1179 epileptic encephalopathy, early infantile, 57 9.4
1180 elliptocytosis 3 9.4
1181 central centrifugal cicatricial alopecia 9.4
1182 pain sensitivity quantitative trait locus 1 9.4
1183 long qt syndrome 8 9.4
1184 pancreatic cancer 5 9.4
1185 leukodystrophy, hypomyelinating, 19, transient infantile 9.4
1186 juvenile arthritis 9.4
1187 tendinopathy 9.4
1188 tendinitis 9.4
1189 chlamydia pneumonia 9.4
1190 autoimmune gastritis 9.4
1191 autoimmune pancreatitis 9.4
1192 acute diarrhea 9.4
1193 otomycosis 9.4
1194 tick-borne encephalitis 9.4
1195 tooth agenesis 9.4
1196 alternating hemiplegia of childhood 9.4
1197 vitelliform macular dystrophy 9.4
1198 fetal alcohol syndrome 9.4
1199 alcohol-related birth defect 9.4
1200 female breast cancer 9.4
1201 brachyolmia 9.4
1202 vitamin b12 deficiency 9.4
1203 polycystic liver disease 9.4
1204 paraganglioma 9.4
1205 cervical dystonia 9.4
1206 ovarian serous carcinoma 9.4
1207 withdrawal disorder 9.4
1208 sexual disorder 9.4
1209 osteoblastoma 9.4
1210 ischemic colitis 9.4
1211 microscopic colitis 9.4
1212 collagenous colitis 9.4
1213 lymphocytic colitis 9.4
1214 crohn's colitis 9.4
1215 sclerosteosis 9.4
1216 ptosis 9.4
1217 autoimmune neuropathy 9.4
1218 drug allergy 9.4
1219 hypomyelinating leukodystrophy 9.4
1220 hereditary lymphedema i 9.4
1221 oligoasthenoteratozoospermia 9.4
1222 physical disorder 9.4
1223 intestinal pseudo-obstruction 9.4
1224 myoglobinuria 9.4
1225 cryptococcal meningitis 9.4
1226 hepatic veno-occlusive disease 9.4
1227 endometrial hyperplasia 9.4
1228 peroxisomal biogenesis disorder 9.4
1229 familial glucocorticoid deficiency 9.4
1230 aortic dissection 9.4
1231 sitosterolemia 9.4
1232 sting-associated vasculopathy with onset in infancy 9.4
1233 familial episodic pain syndrome 9.4
1234 cysticercosis 9.4
1235 pigmentation disease 9.4
1236 keratoconus 9.4
1237 xerophthalmia 9.4
1238 thymus lymphoma 9.4
1239 pleomorphic lipoma 9.4
1240 parotitis 9.4
1241 viral meningitis 9.4
1242 berylliosis 9.4
1243 silicosis 9.4
1244 dentin caries 9.4
1245 viral pneumonia 9.4
1246 microinvasive gastric cancer 9.4
1247 lactose intolerance 9.4
1248 blind loop syndrome 9.4
1249 wolfram syndrome 9.4
1250 cystinosis 9.4
1251 dirofilariasis 9.4
1252 japanese encephalitis 9.4
1253 strongyloidiasis 9.4
1254 cholesteatoma of middle ear 9.4
1255 lipoid nephrosis 9.4
1256 hemiplegia 9.4
1257 alport syndrome 9.4
1258 discitis 9.4
1259 pasteurellosis 9.4
1260 brucellosis 9.4
1261 prostatic hypertrophy 9.4
1262 anhidrosis 9.4
1263 disseminated intravascular coagulation 9.4
1264 microcytic anemia 9.4
1265 keratomalacia 9.4
1266 plummer's disease 9.4
1267 megacolon 9.4
1268 endometriosis of ovary 9.4
1269 horner's syndrome 9.4
1270 patau syndrome 9.4
1271 protein-energy malnutrition 9.4
1272 vitreous syneresis 9.4
1273 hepatorenal syndrome 9.4
1274 coronary thrombosis 9.4
1275 denture stomatitis 9.4
1276 conn's syndrome 9.4
1277 sympathetic ophthalmia 9.4
1278 cryptococcosis 9.4
1279 vaginal disease 9.4
1280 pica disease 9.4
1281 lymphocytic choriomeningitis 9.4
1282 aseptic meningitis 9.4
1283 oligohydramnios 9.4
1284 atypical depressive disorder 9.4
1285 alcoholic hepatitis 9.4
1286 von willebrand's disease 9.4
1287 hepatitis a 9.4
1288 hemolytic-uremic syndrome 9.4
1289 acute leukemia 9.4
1290 paracoccidioidomycosis 9.4
1291 migraine without aura 9.4
1292 guillain-barre syndrome 9.4
1293 cardiovascular system disease 9.4
1294 branch retinal artery occlusion 9.4
1295 central retinal artery occlusion 9.4
1296 allergic bronchopulmonary aspergillosis 9.4
1297 nontoxic goiter 9.4
1298 nodular goiter 9.4
1299 endemic goiter 9.4
1300 right bundle branch block 9.4
1301 diabetic cataract 9.4
1302 urethritis 9.4
1303 premature ejaculation 9.4
1304 beriberi 9.4
1305 hepatic infarction 9.4
1306 opisthorchiasis 9.4
1307 urinary schistosomiasis 9.4
1308 interstitial cystitis 9.4
1309 poems syndrome 9.4
1310 root caries 9.4
1311 anus cancer 9.4
1312 azoospermia 9.4
1313 oral candidiasis 9.4
1314 benign neonatal seizures 9.4
1315 niemann-pick disease 9.4
1316 reye syndrome 9.4
1317 aggressive periodontitis 9.4
1318 urticaria 9.4
1319 ectropion 9.4
1320 alcohol use disorder 9.4
1321 renovascular hypertension 9.4
1322 hypoglycemic coma 9.4
1323 ventricular septal defect 9.4
1324 pneumothorax 9.4
1325 heart septal defect 9.4
1326 retinal vascular occlusion 9.4
1327 thyroid gland cancer 9.4
1328 neuroendocrine carcinoma 9.4
1329 calcinosis 9.4
1330 viral hepatitis 9.4
1331 malignant skin fibrous histiocytoma 9.4
1332 endodermal sinus tumor 9.4
1333 gaucher's disease 9.4
1334 leiomyosarcoma 9.4
1335 rectum adenocarcinoma 9.4
1336 neuroma 9.4
1337 placental choriocarcinoma 9.4
1338 maxillary sinusitis 9.4
1339 post-traumatic stress disorder 9.4
1340 intestinal perforation 9.4
1341 coccidiosis 9.4
1342 ectodermal dysplasia 9.4
1343 atypical teratoid rhabdoid tumor 9.4
1344 amelogenesis imperfecta 9.4
1345 blood platelet disease 9.4
1346 focal epilepsy 9.4
1347 transient cerebral ischemia 9.4
1348 ankylosis 9.4
1349 pharyngitis 9.4
1350 keratopathy 9.4
1351 motor neuron disease 9.4
1352 craniosynostosis 9.4
1353 macrocytic anemia 9.4
1354 west nile encephalitis 9.4
1355 west nile fever 9.4
1356 neonatal jaundice 9.4
1357 central retinal vein occlusion 9.4
1358 psychotic disorder 9.4
1359 vernal conjunctivitis 9.4
1360 hematologic cancer 9.4
1361 reflex epilepsy 9.4
1362 opiate dependence 9.4
1363 cervicitis 9.4
1364 larynx cancer 9.4
1365 cystic teratoma 9.4
1366 sick building syndrome 9.4
1367 acrodermatitis 9.4
1368 glycogen storage disease 9.4
1369 tic disorder 9.4
1370 parasitic protozoa infectious disease 9.4
1371 acalculous cholecystitis 9.4
1372 congenital nonspherocytic hemolytic anemia 9.4
1373 laryngeal squamous cell carcinoma 9.4
1374 bursitis 9.4
1375 cystic kidney disease 9.4
1376 anuria 9.4
1377 breast ductal carcinoma 9.4
1378 interstitial lung disease 9.4
1379 papillary adenocarcinoma 9.4
1380 papillary carcinoma 9.4
1381 gallbladder cancer 9.4
1382 cutis laxa 9.4
1383 gastric dilatation 9.4
1384 neurodermatitis 9.4
1385 central nervous system disease 9.4
1386 pediatric osteosarcoma 9.4
1387 bone osteosarcoma 9.4
1388 chronic wasting disease 9.4
1389 choroid plexus cancer 9.4
1390 atypical choroid plexus papilloma 9.4
1391 aortic aneurysm 9.4
1392 bladder disease 9.4
1393 rhabdoid cancer 9.4
1394 pleural empyema 9.4
1395 pituitary adenoma 9.4
1396 skull base cancer 9.4
1397 placental insufficiency 9.4
1398 acute myocarditis 9.4
1399 merkel cell carcinoma 9.4
1400 nail disease 9.4
1401 syphilis 9.4
1402 pulmonary immaturity 9.4
1403 coronary stenosis 9.4
1404 ebola hemorrhagic fever 9.4
1405 large cell carcinoma 9.4
1406 lung large cell carcinoma 9.4
1407 holoprosencephaly 9.4
1408 proliferative glomerulonephritis 9.4
1409 ependymoblastoma 9.4
1410 adenosquamous carcinoma 9.4
1411 sebaceous adenocarcinoma 9.4
1412 laryngeal adenoid cystic carcinoma 9.4
1413 phencyclidine abuse 9.4
1414 nutritional deficiency disease 9.4
1415 ureteral obstruction 9.4
1416 testicular yolk sac tumor 9.4
1417 schizoaffective disorder 9.4
1418 nasal cavity squamous cell carcinoma 9.4
1419 pneumonia 9.4
1420 volkmann contracture 9.4
1421 oral submucous fibrosis 9.4
1422 congenital hemolytic anemia 9.4
1423 malignant peripheral nerve sheath tumor 9.4
1424 paraplegia 9.4
1425 acute stress disorder 9.4
1426 thyroid hyalinizing trabecular adenoma 9.4
1427 amphetamine abuse 9.4
1428 fibrillary astrocytoma 9.4
1429 juvenile rheumatoid arthritis 9.4
1430 juvenile pilocytic astrocytoma 9.4
1431 hepatoblastoma 9.4
1432 mitochondrial metabolism disease 9.4
1433 dentin dysplasia 9.4
1434 t-cell lymphoblastic leukemia/lymphoma 9.4
1435 thyroiditis 9.4
1436 psammomatous meningioma 9.4
1437 axonal neuropathy 9.4
1438 superficial urinary bladder cancer 9.4
1439 pituitary hypoplasia 9.4
1440 malignant pleural mesothelioma 9.4
1441 macular holes 9.4
1442 fetal adenoma 9.4
1443 appendicitis 9.4
1444 ileus 9.4
1445 pyridoxine deficiency anemia 9.4
1446 arthritis 9.4
1447 retinal artery occlusion 9.4
1448 bullous pemphigoid 9.4
1449 scarlet fever 9.4
1450 nervous system disease 9.4
1451 subacute delirium 9.4
1452 eating disorder 9.4
1453 vascular dementia 9.4
1454 intermediate coronary syndrome 9.4
1455 lupus erythematosus 9.4
1456 rosacea 9.4
1457 skin melanoma 9.4
1458 achalasia 9.4
1459 amebiasis 9.4
1460 diabetic macular edema 9.4
1461 mast-cell leukemia 9.4
1462 scotoma 9.4
1463 iridocyclitis 9.4
1464 lipid storage disease 9.4
1465 bacterial meningitis 9.4
1466 dacryoadenitis 9.4
1467 lassa fever 9.4
1468 neurofibroma 9.4
1469 babesiosis 9.4
1470 congenital nystagmus 9.4
1471 aphthous stomatitis 9.4
1472 pulmonary emphysema 9.4
1473 bacterial conjunctivitis 9.4
1474 trichinosis 9.4
1475 periodontosis 9.4
1476 dacryocystitis 9.4
1477 toxoplasmosis 9.4
1478 heroin dependence 9.4
1479 albinism 9.4
1480 nonsyndromic deafness 9.4
1481 tetrahydrobiopterin deficiency 9.4
1482 actg2-related disorders 9.4
1483 best vitelliform macular dystrophy 9.4
1484 clcn2-related leukoencephalopathy 9.4
1485 creatine deficiency syndromes 9.4
1486 dysferlinopathy 9.4
1487 grin1-related neurodevelopmental disorder 9.4
1488 grin2b-related neurodevelopmental disorder 9.4
1489 hereditary dystonia 9.4
1490 kcnt1-related epilepsy 9.4
1491 malignant hyperthermia susceptibility 9.4
1492 mitochondrial disorders 9.4
1493 plp1 disorders 9.4
1494 trpv4-associated disorders 9.4
1495 adrenomyeloneuropathy 9.4
1496 al amyloidosis 9.4
1497 ameloblastic carcinoma 9.4
1498 carcinoid syndrome 9.4
1499 carcinoma showing thymus-like differentiation 9.4
1500 central serous chorioretinopathy 9.4
1501 cerulean cataract 9.4
1502 ciguatera fish poisoning 9.4
1503 congenital contractures 9.4
1504 congenital lymphedema 9.4
1505 cramp-fasciculation syndrome 9.4
1506 dwarfism 9.4
1507 early-onset, autosomal dominant alzheimer disease 9.4
1508 encephalocele 9.4
1509 enteropathica 9.4
1510 exencephaly 9.4
1511 familial sick sinus syndrome 9.4
1512 fetal thalidomide syndrome 9.4
1513 granulocytopenia 9.4
1514 hansen's disease 9.4
1515 hemorrhagic shock and encephalopathy syndrome 9.4
1516 hyperthermia induced defects 9.4
1517 idiopathic edema 9.4
1518 kshv inflammatory cytokine syndrome 9.4
1519 leukemia, t-cell, chronic 9.4
1520 med23 9.4
1521 mitochondrial dna-associated leigh syndrome 9.4
1522 mycobacterium chelonae 9.4
1523 neisseria meningitidis infection 9.4
1524 non-involuting congenital hemangioma 9.4
1525 ornithinemia 9.4
1526 paroxysmal cold hemoglobinuria 9.4
1527 pelizaeus-merzbacher-like disease 9.4
1528 polymyositis 9.4
1529 post-traumatic epilepsy 9.4
1530 pure autonomic failure 9.4
1531 pustulosis palmaris et plantaris 9.4
1532 refsum disease with increased pipecolic acidemia 9.4
1533 ring chromosome 2 9.4
1534 ring chromosome 3 9.4
1535 ring chromosome 8 9.4
1536 selenium poisoning 9.4
1537 skeletal dysplasias 9.4
1538 spinal shock 9.4
1539 stachybotrys chartarum 9.4
1540 staphylococcal toxic shock syndrome 9.4
1541 sudden arrhythmia death syndrome 9.4
1542 tetraploidy 9.4
1543 visceral steatosis 9.4
1544 vitreoretinal degeneration 9.4
1545 raynaud phenomenon 9.4
1546 schindler disease 9.4
1547 age-related hearing loss 9.4
1548 hereditary hypophosphatemic rickets 9.4
1549 atrial fibrillation and stroke 9.4
1550 cerebral hypoxia 9.4
1551 dementia - subcortical 9.4
1552 hemifacial spasm 9.4
1553 hypertonia 9.4
1554 infantile hypotonia 9.4
1555 myoclonus 9.4
1556 paraneoplastic syndromes 9.4
1557 spasticity 9.4
1558 differentiated thyroid carcinoma 9.4
1559 systemic autoimmune disease 9.4
1560 neonatal hypoxic and ischemic brain injury 9.4
1561 epithelioid hemangioendothelioma 9.4
1562 inflammatory myopathy with abundant macrophages 9.4
1563 rare hemorrhagic disorder 9.4
1564 pulmonary arterial hypertension associated with another disease 9.4
1565 isolated focal cortical dysplasia type i 9.4
1566 qualitative or quantitative defects of dysferlin 9.4
1567 toxic oil syndrome 9.4
1568 virus-associated trichodysplasia spinulosa 9.4
1569 wild type attr amyloidosis 9.4
1570 ring chromosome 9.4
1571 defect in v-atpase 9.4
1572 acyl-coa dehydrogenase deficiency 9.4
1573 snakebite envenomation 9.4
1574 scorpion envenomation 9.4
1575 cyanide poisoning 9.4
1576 chronic enteropathy associated with slco2a1 gene 9.4
1577 ethylene glycol poisoning 9.4
1578 paraquat poisoning 9.4
1579 radiation proctitis 9.4
1580 parenteral nutrition-associated cholestasis 9.4
1581 staphylococcal scarlet fever 9.4
1582 mild hyperphenylalaninemia 9.4
1583 polyploidy 9.4
1584 antenatal bartter syndrome 9.4
1585 coronary ostial stenosis or atresia 9.4
1586 pheochromocytoma-paraganglioma 9.4
1587 streptococcal toxic-shock syndrome 9.4

Graphical network of the top 20 diseases related to Isolated Optic Neuritis:



Diseases related to Isolated Optic Neuritis

Symptoms & Phenotypes for Isolated Optic Neuritis

GenomeRNAi Phenotypes related to Isolated Optic Neuritis according to GeneCards Suite gene sharing:

26 (showing 1, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Negative genetic interaction between BLM-/- and BLM+/+ GR00255-A-1 8.62 CNP MBP

Drugs & Therapeutics for Isolated Optic Neuritis

Drugs for Isolated Optic Neuritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(showing 21, show less)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Prednisolone phosphate Approved, Vet_approved Phase 3 302-25-0
2
Methylprednisolone Approved, Vet_approved Phase 3 83-43-2 6741
3
Methylprednisolone hemisuccinate Approved Phase 3 2921-57-5
4
Prednisone Approved, Vet_approved Phase 3 53-03-2 5865
5
Prednisolone Approved, Vet_approved Phase 3 50-24-8 5755
6 Prednisolone acetate Approved, Vet_approved Phase 3 52-21-1
7
Prednisolone hemisuccinate Experimental Phase 3 2920-86-7
8 Gastrointestinal Agents Phase 3
9 Methylprednisolone Acetate Phase 3
10 Hormones Phase 3
11 Antineoplastic Agents, Hormonal Phase 3
12 Hormone Antagonists Phase 3
13 Antiemetics Phase 3
14 glucocorticoids Phase 3
15 Neuroprotective Agents Phase 3
16 Anti-Inflammatory Agents Phase 3
17 Protective Agents Phase 3
18
Phenytoin Approved, Vet_approved Phase 2 57-41-0 1775
19 Sodium Channel Blockers Phase 2
20 Diuretics, Potassium Sparing Phase 2
21 Anticonvulsants Phase 2

Interventional clinical trials:

(showing 3, show less)
# Name Status NCT ID Phase Drugs
1 Optic Neuritis Treatment Trial (ONTT) Unknown status NCT00000146 Phase 3 Methylprednisolone;Prednisone
2 A Phase II Double Blind, Randomized, Placebo Controlled Trial of Neuroprotection With Phenytoin in Acute Optic Neuritis Completed NCT01451593 Phase 2 Phenytoin;Placebo
3 Longitudinal Optic Neuritis Study (LONS) Unknown status NCT00000147 Methylprednisolone;Prednisone

Search NIH Clinical Center for Isolated Optic Neuritis

Genetic Tests for Isolated Optic Neuritis

Anatomical Context for Isolated Optic Neuritis

MalaCards organs/tissues related to Isolated Optic Neuritis:

40
Eye, Brain, T Cells, Cortex, Spinal Cord, Testes, B Cells

Publications for Isolated Optic Neuritis

Articles related to Isolated Optic Neuritis:

(showing 128, show less)
# Title Authors PMID Year
1
Longitudinal Development of Peripapillary Hyper-Reflective Ovoid Masslike Structures Suggests a Novel Pathological Pathway in Multiple Sclerosis. 61
32426856 2020
2
Effect of phenytoin on retinal ganglion cells in acute isolated optic neuritis. 61
32212009 2020
3
Clinical Features and Outcomes of Pediatric Monophasic and Recurrent Idiopathic Optic Neuritis. 61
31566057 2020
4
Sleep disturbance and cognitive decline in multiple sclerosis patients with isolated optic neuritis as the first demyelinating event. 61
31432354 2020
5
Clinical spectrum of inflammatory central nervous system demyelinating disorders associated with antibodies against myelin oligodendrocyte glycoprotein. 61
30365980 2019
6
Epidemiologic and Clinical Characteristics of Optic Neuritis in Japan. 61
31196727 2019
7
Cross-modal plasticity among sensory networks in neuromyelitis optica spectrum disorders. 61
29771186 2019
8
Clinical presentation of optic neuritis with autoantibodies anti-myelin oligodendrocyte glycoprotein. 61
29972029 2019
9
Neurological presentations of Bartonella henselae infection. 61
30368695 2019
10
Should Spinal MRI Be Routinely Performed in Patients With Clinically Isolated Optic Neuritis? 61
30001224 2018
11
Isolated optic neuritis with a concurrent abnormal trigeminal nucleus on imaging: case report of a rare complication of herpes zoster ophthalmicus. 61
30286736 2018
12
Optic neuritis in dogs: 96 cases (1983-2016). 61
29251394 2018
13
Different features between pediatric-onset and adult-onset patients who are seropositive for MOG-IgG: A multicenter study in South China. 61
29957392 2018
14
MRI of the first event in pediatric acquired demyelinating syndromes with antibodies to myelin oligodendrocyte glycoprotein. 61
29423614 2018
15
Prevalence of Myelin Oligodendrocyte Glycoprotein and Aquaporin-4-IgG in Patients in the Optic Neuritis Treatment Trial. 61
29470571 2018
16
MOG Spectrum Disorders and Role of MOG-Antibodies in Clinical Practice. 61
28859212 2018
17
Central Nervous System Involvement in Common Variable Immunodeficiency: A Case of Acute Unilateral Optic Neuritis in a 26-Year-Old Italian Patient. 61
30555409 2018
18
Aquaporin 4 Antibody in the Korean Patient with New-Onset Optic Neuritis. 61
27668553 2018
19
Clinical presentation and prognosis in MOG-antibody disease: a UK study. 61
29136091 2017
20
MOG-IgG associated optic neuritis is not multiple sclerosis. 61
29166458 2017
21
Thickness of macular inner retinal layers and peripapillary retinal nerve fibre layer in neuromyelitis optica spectrum optic neuritis and isolated optic neuritis with one episode. 61
27775238 2017
22
Isolated optic neuritis associated with Mycoplasma pneumoniae infection: report of two cases and literature review. 61
28321515 2017
23
Recurrent isolated optic neuritis: A study on 22 patients. 61
29114368 2017
24
Increased interleukin-27 cytokine expression in the central nervous system of multiple sclerosis patients. 61
28738904 2017
25
An abnormal periventricular magnetization transfer ratio gradient occurs early in multiple sclerosis. 61
28043954 2017
26
Myelin Oligodendrocyte Glycoprotein: Deciphering a Target in Inflammatory Demyelinating Diseases. 61
28533781 2017
27
The neuromyelitis optica presentation and the aquaporin-4 antibody in HIV-seropositive and seronegative patients in KwaZulu-Natal, South Africa. 61
29568625 2017
28
Disease Activity and Conversion into Multiple Sclerosis after Optic Neuritis Is Treated with Erythropoietin. 61
27706045 2016
29
Clinical spectrum associated with MOG autoimmunity in adults: significance of sharing rodent MOG epitopes. 61
27147513 2016
30
MRI and retinal abnormalities in isolated optic neuritis with myelin oligodendrocyte glycoprotein and aquaporin-4 antibodies: a comparative study. 61
25749692 2016
31
Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses. 61
26537743 2016
32
Status of diagnostic approaches to AQP4-IgG seronegative NMO and NMO/MS overlap syndromes. 61
26530512 2016
33
Oligoclonal bands predict multiple sclerosis in children with optic neuritis. 61
25820181 2015
34
Antibodies to aquaporin 4, myelin-oligodendrocyte glycoprotein, and the glycine receptor α1 subunit in patients with isolated optic neuritis. 61
25506781 2015
35
Neurogenic vision loss: Causes and outcome. An experience from a tertiary center in Northern India. 61
25288834 2014
36
Autoantibody biomarkers in childhood-acquired demyelinating syndromes: results from a national surveillance cohort. 61
24133290 2014
37
Diagnosis and classification of autoimmune optic neuropathy. 61
24424177 2014
38
The diagnosis of multiple sclerosis and the various related demyelinating syndromes: a critical review. 61
24524923 2014
39
Analysis of spectral domain optical coherence tomography measurements in optic neuritis: differences in neuromyelitis optica, multiple sclerosis, isolated optic neuritis and normal healthy controls. 61
23889747 2014
40
Macular spectral domain optical coherence tomography findings in Tanzanian endemic optic neuropathy. 61
24018312 2013
41
Predicting multiple sclerosis following isolated optic neuritis in children. 61
23663558 2013
42
Update in pediatric optic neuritis. 61
23872812 2013
43
Aquaporin-4 antibody negative recurrent isolated optic neuritis: clinical evidence for disease heterogeneity. 61
23735776 2013
44
The spectrum of MOG autoantibody-associated demyelinating diseases. 61
23797245 2013
45
Noninvasive assessments of optic nerve neurodegeneration in transgenic mice with isolated optic neuritis. 61
23722393 2013
46
Distinguishing optic neuritis in neuromyelitis optica spectrum disease from multiple sclerosis: a novel magnetic resonance imaging scoring system. 61
23609766 2013
47
[Signification of Epstein-Barr virus detection in the cerebrospinal fluid of a patient with human immunodeficiency virus related Burkitt lymphoma]. 61
23747673 2013
48
[Anti-MOG antibody in different types of immune-mediated optic neuritis]. 61
23336409 2012
49
Anti-aquaporin-4 antibody-positive recurrent isolated optic neuritis and primary Sjögren's syndrome. 61
22327571 2012
50
Serum GFAP levels in optic neuropathies. 61
22410258 2012
51
25-hydroxyvitamin D Concentrations in Patients with Optic Neuritis as a Clinically Isolated Syndrome and Healthy Controls. 61
22708027 2012
52
Isolated optic neuritis secondary to presumed tuberculosis in an immunocompetent child. 61
22582557 2012
53
Retinal nerve fibre layer thinning in patients with clinically isolated optic neuritis and early treatment with interferon-beta. 61
23272128 2012
54
Optic neuritis in an ethnically diverse population: higher risk of atypical cases in patients of African or African-Caribbean heritage. 61
21920560 2012
55
Optic neuritis in an adult patient with chickenpox. 61
23320222 2012
56
Early pericalcarine atrophy in acute optic neuritis is associated with conversion to multiple sclerosis. 61
21297149 2011
57
Clinical features and outcome of childhood optic neuritis at Queen Sirikit National Institute of Child Health. 61
22043775 2011
58
Anti-aquaporin-4 antibodies in Devic's neuromyelitis optica: therapeutic implications. 61
21179621 2010
59
Central nervous system involvement in Sjögren's syndrome: unusual, but not unremarkable--clinical, serological characteristics and outcomes in a large cohort of Italian patients. 61
20444860 2010
60
[Devic's neuromyelitis optica and related neurological disorders]. 61
20116202 2010
61
Chronic relapsing inflammatory optic neuropathy. 61
20436750 2010
62
Neuroplasticity predicts outcome of optic neuritis independent of tissue damage. 61
20186956 2010
63
Childhood optic neuritis: the pediatric neurologist's perspective. 61
18945627 2009
64
Multiple sclerosis and acute disseminated encephalomyelitis diagnosed in children after long-term follow-up: comparison of presenting features. 61
19018840 2009
65
Pediatric optic neuritis: brain MRI abnormalities and risk of multiple sclerosis. 61
19273821 2009
66
Disability in optic neuritis correlates with diffusion tensor-derived directional diffusivities. 61
19073948 2009
67
Management of optic neuritis and impact of clinical trials: an international survey. 61
18926549 2009
68
Cognitive dysfunction 24-31 years after isolated optic neuritis. 61
18573827 2008
69
Management of optic neuritis in Canada: survey of ophthalmologists and neurologists. 61
18574931 2008
70
Predictive role of evoked potential examinations in patients with clinically isolated optic neuritis in light of the revised McDonald criteria. 61
18208873 2008
71
[Management of isolated optic neuritis in France: survey of neurologists and ophthalmologists]. 61
18405773 2008
72
Neuromyelitis optica: clinical syndrome and the NMO-IgG autoantibody marker. 61
18219825 2008
73
Early relapse risk after a first CNS inflammatory demyelination episode: examining international consensus definitions. 61
18039234 2007
74
Prognosis of Taiwanese patients with isolated optic neuritis after intravenous methylprednisolone pulse therapy. 61
17711799 2007
75
Optic neuritis. 61
17577863 2007
76
Building different mouse models for human MS. 61
17376825 2007
77
Diagnosis and treatment of neuromyelitis optica. 61
17215722 2007
78
Isolated optic neuritis from an identified Gnathostoma spinigerum. 61
17294395 2007
79
Isolated bilateral optic neuritis in acute disseminated encephalomyelitis. 61
17083545 2006
80
Retinal ganglion cell damage induced by spontaneous autoimmune optic neuritis in MOG-specific TCR transgenic mice. 61
16828169 2006
81
Is the frequency of abnormalities on magnetic resonance imaging in isolated optic neuritis related to the prevalence of multiple sclerosis? A global comparison. 61
16788011 2006
82
Myelin oligodendrocyte glycoprotein-specific T and B cells cooperate to induce a Devic-like disease in mice. 61
16955141 2006
83
Immunohistochemical evidence of inducible nitric oxide synthase and nitrotyrosine in a case of clinically isolated optic neuritis. 61
16845306 2006
84
The approach to bilateral simultaneous isolated optic neuritis. 61
16622079 2006
85
Selective magnetization transfer ratio decrease in the visual cortex following optic neuritis. 61
16495327 2006
86
Multifocal visual evoked potential analysis of inflammatory or demyelinating optic neuritis. 61
16406544 2006
87
The natural history of optic neuritis. 61
16819420 2006
88
Systemic T-cell activation in acute clinically isolated optic neuritis. 61
15833372 2005
89
[Treatment of optic neuritis]. 61
14753126 2004
90
Spinal cord MRI in clinically isolated optic neuritis. 61
14617723 2003
91
Myelin oligodendrocyte glycoprotein-specific T cell receptor transgenic mice develop spontaneous autoimmune optic neuritis. 61
12732654 2003
92
Optic neuritis: characteristics and visual outcome. 61
12757063 2003
93
[Inflammatory optic neuropathies]. 61
11828635 2001
94
Behçet's disease: diagnostic and prognostic aspects of neurological involvement. 61
11284141 2001
95
The prognosis of idiopathic optic neuritis. 61
11205365 2000
96
Long-term follow-up of isolated optic neuritis: the risk of developing multiple sclerosis, its outcome, and the prognostic role of paraclinical tests. 61
10525973 1999
97
Is sphenoid sinus opacity significant in patients with optic neuritis? 61
10396389 1999
98
Isolated optic neuritis and its prognosis for multiple sclerosis: a clinical and paraclinical study with evoked potentials. CSF examination and brain MRI. 61
8933225 1996
99
An analysis of VEP components in optic neuritis. 61
7781577 1995
100
Cranial MRI in idiopathic retinal vasculitis. 61
7751862 1995
101
Early treatment of multiple sclerosis with Rebif (recombinant human interferon beta): design of the study. 61
9345394 1995
102
Systemic diseases associated with intermediate uveitis. 61
8287507 1993
103
Brain magnetic resonance imaging in acute optic neuritis. Experience of the Optic Neuritis Study Group. 61
8352671 1993
104
Frequent involvement of the optic radiation in patients with acute isolated optic neuritis. 61
1734327 1992
105
Uhthoff's symptom in optic neuritis: relationship to magnetic resonance imaging and development of multiple sclerosis. 61
1654765 1991
106
Frequency and clinical significance of Lyme seropositivity in patients with isolated optic neuritis. 61
2027487 1991
107
Magnetic resonance imaging of inflammatory and demyelinating white-matter diseases of childhood. 61
2338183 1990
108
Occurrence of MRI abnormalities in patients with isolated optic neuritis. 61
2289505 1990
109
Convergence-evoked nystagmus. 61
2296365 1990
110
Cognitive event-related potentials in multiple sclerosis. 61
2598002 1989
111
Contributions of magnetic resonance imaging to the diagnosis of MS in isolated optic neuritis. 61
2608781 1989
112
T-lymphocyte subpopulations in acute unilateral optic neuritis. 61
2570391 1989
113
Magnetic resonance imaging in Leber's optic neuropathy. 61
2732742 1989
114
The early risk of multiple sclerosis after optic neuritis. 61
3221224 1988
115
Evoked potentials in suspected multiple sclerosis: diagnostic value and prediction of clinical course. 61
3128646 1988
116
A reassessment of the risk of multiple sclerosis developing in patients with optic neuritis after extended follow-up. 61
3497228 1987
117
Cognitive function in recent-onset demyelinating diseases. 61
3778246 1986
118
Acute optic neuritis: a prospective study of risk factors for multiple sclerosis. 61
3783173 1986
119
Magnetic resonance imaging of the brain in isolated optic neuritis. 61
3767679 1986
120
Optic neuritis following chickenpox in adults. 61
3723155 1986
121
Isolated idiopathic optic neuritis. Analysis of free kappa-light chains in cerebrospinal fluid and correlation with nuclear magnetic resonance findings. 61
3083803 1986
122
Disseminated lesions at presentation in patients with optic neuritis. 61
3950632 1986
123
[Visual evoked potentials (VEP's) obtained by black and white or red and black checkerboard inversion. Results in healthy subjects and in multilocular sclerosis patients]. 61
6463311 1984
124
Interferon-alpha and interferon-gamma production capacity of idiopathic isolated optic neuritis patients. 61
6409925 1983
125
Lymphocyte subpopulations in patients with multiple sclerosis. 61
6221079 1983
126
[Cerebrospinal fluid findings in isolated optic neuritis]. 61
6350131 1983
127
Multimodality evoked potentials and electrically elicited blink reflex in optic neuritis. 61
6181223 1982
128
Multiple regression analysis of diagnostic predictors in optic nerve disease. 61
7225960 1981

Variations for Isolated Optic Neuritis

Expression for Isolated Optic Neuritis

Search GEO for disease gene expression data for Isolated Optic Neuritis.

Pathways for Isolated Optic Neuritis

Pathways related to Isolated Optic Neuritis according to GeneCards Suite gene sharing:

(showing 3, show less)
# Super pathways Score Top Affiliating Genes
1 11.69 MBP CNP
2 10.75 MBP CNP
3 9.53 MBP CNP

GO Terms for Isolated Optic Neuritis

Cellular components related to Isolated Optic Neuritis according to GeneCards Suite gene sharing:

(showing 2, show less)
# Name GO ID Score Top Affiliating Genes
1 synapse GO:0045202 8.96 MBP CNP
2 myelin sheath GO:0043209 8.62 MBP CNP

Biological processes related to Isolated Optic Neuritis according to GeneCards Suite gene sharing:

(showing 3, show less)
# Name GO ID Score Top Affiliating Genes
1 chemical synaptic transmission GO:0007268 9.16 MBP CNP
2 response to toxic substance GO:0009636 8.96 MBP CNP
3 substantia nigra development GO:0021762 8.62 MBP CNP

Sources for Isolated Optic Neuritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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