MCID: ISR001
MIFTS: 18

Israeli Tick Typhus

Categories: Infectious diseases

Aliases & Classifications for Israeli Tick Typhus

MalaCards integrated aliases for Israeli Tick Typhus:

Name: Israeli Tick Typhus 12 15
Israeli Spotted Fever 12

Classifications:



External Ids:

Disease Ontology 12 DOID:0050043

Summaries for Israeli Tick Typhus

Disease Ontology : 12 A spotted fever that has material basis in Rickettsia conorii subsp israelensis, which is transmitted by ticks (Rhipicephalus sanguineus). The infection has symptom fever, has symptom eschar, has symptom regional adenopathy, and has symptom maculopapular rash on extremities.

MalaCards based summary : Israeli Tick Typhus, also known as israeli spotted fever, is related to spotted fever and boutonneuse fever, and has symptoms including fever, eschar and regional adenopathy. An important gene associated with Israeli Tick Typhus is PLEKHG4 (Pleckstrin Homology And RhoGEF Domain Containing G4). Affiliated tissues include endothelial.

Related Diseases for Israeli Tick Typhus

Graphical network of the top 20 diseases related to Israeli Tick Typhus:



Diseases related to Israeli Tick Typhus

Symptoms & Phenotypes for Israeli Tick Typhus

Symptoms:

12
  • fever
  • eschar
  • regional adenopathy
  • maculopapular rash on extremities

Drugs & Therapeutics for Israeli Tick Typhus

Search Clinical Trials , NIH Clinical Center for Israeli Tick Typhus

Genetic Tests for Israeli Tick Typhus

Anatomical Context for Israeli Tick Typhus

MalaCards organs/tissues related to Israeli Tick Typhus:

40
Endothelial

Publications for Israeli Tick Typhus

Articles related to Israeli Tick Typhus:

(show all 48)
# Title Authors PMID Year
1
Two Cases of Israeli Spotted Fever with Purpura Fulminans, Sharon District, Israel. 61
29664383 2018
2
Israeli Spotted Fever in Sicily. Description of two cases and minireview. 61
28408252 2017
3
Severe Israeli spotted fever with multiorgan failure in a child. 61
26905298 2016
4
Rickettsia massiliae and Rickettsia conorii Israeli Spotted Fever Strain Differentially Regulate Endothelial Cell Responses. 61
26394396 2015
5
Rickettsia conorii israelensis in Rhipicephalus sanguineus ticks, Sardinia, Italy. 61
24852264 2014
6
Detection of Rickettsia in Rhipicephalus sanguineus ticks and Ctenocephalides felis fleas from southeastern Tunisia by reverse line blot assay. 61
24226919 2014
7
Genome sequence of Rickettsia conorii subsp. israelensis, the agent of Israeli spotted fever. 61
22933760 2012
8
Domestic dogs (Canis familiaris) as reservoir hosts for Rickettsia conorii. 61
21923270 2012
9
Israeli spotted fever, Tunisia. 61
21762610 2011
10
Detection of Rickettsia conorii strains in Portuguese dogs (Canis familiaris). 61
21771547 2011
11
Fatal case of Israeli spotted fever after Mediterranean cruise. 61
19046528 2008
12
Host- and microbe-related risk factors for and pathophysiology of fatal Rickettsia conorii infection in Portuguese patients. 61
18582199 2008
13
Fatal Rickettsia conorii subsp. israelensis infection, Israel. 61
18439372 2008
14
Fatal Israeli spotted fever in a UK traveler to South Portugal. 61
18346246 2008
15
Rickettsia conorii in humans and dogs: a seroepidemiologic survey of two rural villages in Israel. 61
17620644 2007
16
Rickettsia conorii Israeli tick typhus strain isolated from Rhipicephalus sanguineus ticks in Portugal. 61
17767403 2007
17
Ticks and tick-borne Rickettsiae surveillance in Montesinho Natural Park, Portugal. 61
17114695 2006
18
Boutonneuse fever and climate variability. 61
17114701 2006
19
Presence of Rickettsia conorii subsp. israelensis, the causative agent of Israeli spotted fever, in Sicily, Italy, ascertained in a retrospective study. 61
16333093 2005
20
The presence of eschars, but not greater severity, in Portuguese patients infected with Israeli spotted fever. 61
16481514 2005
21
Continous alert for rickettsiosis in Sicily: molecular characterization of Rickettsia sp. obtained from ticks and human beings (1986-2001). 61
16386024 2005
22
Characterization of a tandem repeat polymorphism in Rickettsia strains. 61
16091434 2005
23
Proposal to create subspecies of Rickettsia conorii based on multi-locus sequence typing and an emended description of Rickettsia conorii. 61
15766388 2005
24
[Epidemiologic features of Mediterranean spotted fever in Portugal]. 61
15631855 2003
25
Israeli spotted fever Rickettsia in Sicilian Rhipicephalus sanguineus ticks. 61
12899144 2003
26
Mediterranean spotted fever in Portugal: risk factors for fatal outcome in 105 hospitalized patients. 61
12860641 2003
27
Report of eight cases of fatal and severe Mediterranean spotted fever in Portugal. 61
12860647 2003
28
The dog factor in brown dog tick Rhipicephalus sanguineus (Acari: Ixodidae) infestations in and near human dwellings. 61
12141741 2002
29
Glucose-6-phosphate dehydrogenase deficiency: possible determinant for a fulminant course of Israeli spotted fever. 61
11344735 2000
30
Israeli spotted fever rickettsia (Rickettsia conorii complex) associated with human disease in Portugal. 61
10603225 1999
31
Phylogenetic analysis of spotted fever group rickettsiae by study of the outer surface protein rOmpA. 61
9734038 1998
32
Genetic analysis of isolates of the spotted fever group of rickettsiae belonging to the R. conorii complex. 61
9668445 1998
33
Bacteriostatic and bactericidal activity of levofloxacin against Rickettsia rickettsii, Rickettsia conorii, 'Israeli spotted fever group rickettsia' and Coxiella burnetii. 61
9222041 1997
34
Citrate synthase gene comparison, a new tool for phylogenetic analysis, and its application for the rickettsiae. 61
9103608 1997
35
Arthritis in Israeli spotted fever. 61
8549102 1995
36
Comparative antigenic analysis of spotted fever group rickettsiae from Israel and other closely related organisms. 61
7611567 1995
37
Phylogenetic analysis of the genus Rickettsia by 16S rDNA sequencing. 61
8525055 1995
38
Astrakhan fever rickettsiae: antigenic and genotypic analysis of isolates obtained from human and Rhipicephalus pumilio ticks. 61
7985764 1994
39
Species-specific BALB/c mouse antibodies to rickettsiae studied by western blotting. 61
8050715 1994
40
Differentiation among spotted fever group rickettsiae species by analysis of restriction fragment length polymorphism of PCR-amplified DNA. 61
7910831 1994
41
Fatal Israeli spotted fever in children. 61
8286624 1993
42
Proteinic and genomic identification of spotted fever group rickettsiae isolated in the former USSR. 61
7902843 1993
43
Genotypic identification and phylogenetic analysis of the spotted fever group rickettsiae by pulsed-field gel electrophoresis. 61
8393009 1993
44
Human and tick spotted fever group Rickettsia isolates from Israel: a genotypic analysis. 61
1356998 1992
45
Serum antibodies in rickettsia patients as determined by immunoblotting technique. 61
1350167 1992
46
Tumor necrosis factor alpha and prostaglandin E2 production by human monocyte-derived macrophages infected with spotted fever group rickettsiae. 61
2378446 1990
47
Antigenic polypeptides of Israeli spotted fever isolates compared with other spotted fever group rickettsiae. 61
2378464 1990
48
Relapse of Israeli spotted fever treated with doxycycline. 61
3838833 1985

Variations for Israeli Tick Typhus

Expression for Israeli Tick Typhus

Search GEO for disease gene expression data for Israeli Tick Typhus.

Pathways for Israeli Tick Typhus

GO Terms for Israeli Tick Typhus

Sources for Israeli Tick Typhus

3 CDC
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9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
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56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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