MCID: JMC001
MIFTS: 10

Jamaican Vomiting Sickness

Categories: Rare diseases

Aliases & Classifications for Jamaican Vomiting Sickness

MalaCards integrated aliases for Jamaican Vomiting Sickness:

Name: Jamaican Vomiting Sickness 54
Ackee Poisoning 54

Classifications:



Summaries for Jamaican Vomiting Sickness

NIH Rare Diseases : 54 The following summary is from Orphanet, a European reference portal for information on rare diseases and orphan drugs.Orpha Number: 73423Disease definitionAcute ackee fruit intoxication (also referred to as Jamaican vomiting syndrome or sickness) is caused by the ingestion of unripe Blighia sapida fruits. It is a serious intoxication that is frequent in certain countries in the Caribbean and Western Africa. In contrast, it is rare in France and other Western countries. Intoxication leads to toxic hypoglycaemia and inhibition of neoglucogenesis. The hypoglycaemia is caused by the effect of hypoglycin A, which is found in the arils.Clinical descriptionThe clinical manifestations are severe (coma, convulsions, delirium, toxic hepatitis, acute dehydration and a state of shock) and may lead to death.Management and treatmentTreatment is symptomatic (administration of glucose, IV or per os).PrognosisAlthough the intoxication is generally benign or has a favourable outcome, ingestion of large doses may lead to death: ackee fruit intoxication lead to 29 deaths in 1998 and more than 50 in 2001.Visit the Orphanet disease page for more resources.

MalaCards based summary : Jamaican Vomiting Sickness, also known as ackee poisoning, is related to acute ackee fruit intoxication and hypoglycemia.

Wikipedia : 77 Jamaican vomiting sickness is an acute illness caused by the toxins hypoglycin A and hypoglycin B, which... more...

Related Diseases for Jamaican Vomiting Sickness

Diseases related to Jamaican Vomiting Sickness via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 acute ackee fruit intoxication 11.9
2 hypoglycemia 10.4
3 diarrhea 10.1
4 reye syndrome 10.1

Symptoms & Phenotypes for Jamaican Vomiting Sickness

Drugs & Therapeutics for Jamaican Vomiting Sickness

Search Clinical Trials , NIH Clinical Center for Jamaican Vomiting Sickness

Genetic Tests for Jamaican Vomiting Sickness

Anatomical Context for Jamaican Vomiting Sickness

Publications for Jamaican Vomiting Sickness

Articles related to Jamaican Vomiting Sickness:

(show all 19)
# Title Authors Year
1
Akee fruit and Jamaican vomiting sickness (Blighia sapida Köenig). ( 19446675 )
2009
2
Jamaican vomiting sickness in Toledo, Ohio. ( 8185109 )
1994
3
Hypoglycin and Jamaican vomiting sickness. ( 2183231 )
1990
4
Jamaican vomiting sickness: a study of two adult cases. ( 6488562 )
1984
5
Twin siblings with a Reye's-like syndrome associated with an abnormal organic aciduria, hypoglycemia, diarrhea, and vomiting with close similarities to Jamaican vomiting sickness. ( 7008010 )
1980
6
Identification of 5-hydroxyhexanoic acid in the urine of twin siblings with a Reye's-like syndrome associated with dicarboxylic aciduria and hypoglycaemia and with similarities to Jamaican vomiting sickness. ( 575058 )
1979
7
Identification of 5-hydroxyhexanoic acid in the urine of twin siblings with a syndrome having close similarities to Jamaican vomiting sickness [proceedings]. ( 640132 )
1978
8
Dicarboxylic aciduria as an indicator of defective beta-oxidation in twin siblings with a vomiting sickness and hypoglycaemia similar to Jamaican vomiting sickness [proceedings]. ( 640133 )
1978
9
Organic acids in Reye's like syndrome: similarities with Jamaican vomiting sickness. ( 68256 )
1977
10
Ackee poisoning. ( 64895 )
1977
11
Glycine in ackee poisoning. ( 65690 )
1977
12
Jamaican vomiting sickness. Biochemical investigation of two cases. ( 940578 )
1976
13
Jamaican vomiting sickness: a theoretical investigation. ( 968504 )
1976
14
Jamaican vomiting sickness and Reye's syndrome. ( 995147 )
1976
15
Identification of n-hexanoylglycine in urines from two patients with Jamaican vomiting sickness. ( 1000831 )
1976
16
Glycine in ackee poisoning. ( 63057 )
1976
17
Isovaleric and -methylbutyric acidemias induced by hypoglycin A: mechanism of Jamaican vomiting sickness. ( 5008580 )
1972
18
Toxic hypoglycaemia (Jamaican vomiting sickness). First case reported from the territory of Trinidad and Tobago. ( 13700023 )
1960
19
Tissue changes in experimental ackee poisoning. Pathological changes produced in rabbits. ( 13724058 )
1960

Variations for Jamaican Vomiting Sickness

Expression for Jamaican Vomiting Sickness

Search GEO for disease gene expression data for Jamaican Vomiting Sickness.

Pathways for Jamaican Vomiting Sickness

GO Terms for Jamaican Vomiting Sickness

Sources for Jamaican Vomiting Sickness

3 CDC
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9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
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31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
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45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
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52 NDF-RT
55 NINDS
56 Novoseek
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59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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