MCID: JPN001
MIFTS: 23

Japanese Spotted Fever

Categories: Infectious diseases
Data Licensing
For inquiries, contact:

Aliases & Classifications for Japanese Spotted Fever

MalaCards integrated aliases for Japanese Spotted Fever:

Name: Japanese Spotted Fever 11 14 75
Rickettsia Japonica Spotted Fever 11
Oriental Spotted Fever 11

Classifications:



External Ids:

Disease Ontology 11 DOID:0050050

Summaries for Japanese Spotted Fever

Disease Ontology: 11 A spotted fever that has material basis in Rickettsia japonica, which is transmitted by ticks (Dermacentor taiwanensis and Haemaphysalis flava). The infection has symptom fever, has symptom eschars, has symptom regional adenopathy, and has symptom rash on extremities.

MalaCards based summary: Japanese Spotted Fever, also known as rickettsia japonica spotted fever, is related to spotted fever and epidemic typhus, and has symptoms including fever, eschars and regional adenopathy. An important gene associated with Japanese Spotted Fever is AFF2 (ALF Transcription Elongation Factor 2). Affiliated tissues include kidney, liver and skin.

Wikipedia: 75 Japanese spotted fever is a condition characterized by a rash that has early macules, and later, in some... more...

Related Diseases for Japanese Spotted Fever

Diseases related to Japanese Spotted Fever via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 67)
# Related Disease Score Top Affiliating Genes
1 spotted fever 30.5 PPP1R14A PLEKHG4 HTRA1 CS CRP AFF2
2 epidemic typhus 29.5 SLC36A2 PPP1R14A PLEKHG4 HTRA1 CS CRP
3 scrub typhus 10.6
4 disseminated intravascular coagulation 10.5
5 exanthem 10.5
6 meningoencephalitis 10.2
7 respiratory failure 10.2
8 thrombocytopenia 10.2
9 purpura 10.2
10 hemophagocytic lymphohistiocytosis, familial, 1 10.1
11 adult respiratory distress syndrome 10.1
12 tularemia 10.1
13 rickettsial disease 10.1
14 bacillary angiomatosis 10.1 PPP1R14A HTRA1
15 ornithosis 10.0 HTRA1 CRP
16 familial adult myoclonic epilepsy 10.0 PLEKHG4 AFF2
17 choroiditis 10.0 HTRA1 CRP
18 ureterolithiasis 10.0 IRGC CRP
19 spinocerebellar ataxia 1 10.0 PLEKHG4 AFF2
20 myositis 10.0
21 iga nephropathy 1 10.0
22 ocular motor apraxia 10.0
23 ataxia with vitamin e deficiency 10.0
24 spinocerebellar ataxia 4 10.0
25 gallbladder disease 1 10.0
26 kawasaki disease 10.0
27 encephalitis/encephalopathy, mild, with reversible myelin vacuolization 10.0
28 disease by infectious agent 10.0
29 hemophagocytic lymphohistiocytosis 10.0
30 metabolic acidosis 10.0
31 middle east respiratory syndrome 10.0
32 q fever 10.0
33 lyme disease 10.0
34 aseptic meningitis 10.0
35 toxic shock syndrome 10.0
36 duodenal ulcer 10.0
37 status epilepticus 10.0
38 cholecystitis 10.0
39 iga glomerulonephritis 10.0
40 acute myocarditis 10.0
41 systemic scleroderma 10.0
42 ebola hemorrhagic fever 10.0
43 pneumonia 10.0
44 myocarditis 10.0
45 encephalitis 10.0
46 cytokine deficiency 10.0
47 encephalopathy 10.0
48 meningitis and encephalitis 10.0
49 acute liver failure 10.0
50 spondylosis 10.0 HTRA1 CRP

Graphical network of the top 20 diseases related to Japanese Spotted Fever:



Diseases related to Japanese Spotted Fever

Symptoms & Phenotypes for Japanese Spotted Fever

Symptoms:

11
  • fever
  • eschars
  • regional adenopathy
  • rash on extremities

Drugs & Therapeutics for Japanese Spotted Fever

Search Clinical Trials, NIH Clinical Center for Japanese Spotted Fever

Genetic Tests for Japanese Spotted Fever

Anatomical Context for Japanese Spotted Fever

Organs/tissues related to Japanese Spotted Fever:

MalaCards : Kidney, Liver, Skin

Publications for Japanese Spotted Fever

Articles related to Japanese Spotted Fever:

(show top 50) (show all 123)
# Title Authors PMID Year
1
Effectiveness of fluoroquinolone antimicrobials in addition to tetracyclines for Japanese spotted fever: A retrospective analysis using a national inpatient database. 62
35987471 2022
2
Japanese Spotted Fever and Irreversible Renal Dysfunction during Immunosuppressive Therapy after a Living-Donor Kidney Transplant. 62
36006267 2022
3
A Case of Japanese Spotted Fever Associated with Mild Encephalitis/Encephalopathy with a Reversible Splenial Lesion. 62
35945027 2022
4
Japanese Spotted Fever. 62
35921453 2022
5
Clinical Differentiation of Severe Fever with Thrombocytopenia Syndrome from Japanese Spotted Fever. 62
36016429 2022
6
[Infectious causes and management of Japanese spotted fever and severe fever thrombocytopenia syndrome in Ehime prefecture]. 62
35545515 2022
7
Family cluster of Japanese spotted fever. 62
35021228 2022
8
Serological and molecular survey of tick-borne zoonotic pathogens including severe fever with thrombocytopenia syndrome virus in wild boars in Miyazaki Prefecture, Japan. 62
34953052 2022
9
A new record of Rickettsia japonica in ticks infesting a Burmese ferret-badger in Thailand. 62
35507925 2022
10
The clinical course of 239 cases of Japanese spotted fever in Ise Red Cross Hospital, 2006-2019. 62
34711506 2022
11
Japanese Spotted Fever Complicated With Life-Threatening Ventricular Tachycardia and Acute Cardiac Damage. 62
34729284 2021
12
The presence of Tularemia infection in patients with Japanese spotted fever. 62
33950539 2021
13
Japanese spotted fever and rickettsial pneumonia. 62
33346839 2021
14
Diversity and distribution of ticks in Niigata prefecture, Japan (2016-2018): Changes since 1950. 62
33578257 2021
15
Descriptive epidemiology of rickettsial infections in Japan: Scrub typhus and Japanese spotted fever, 2007-2016. 62
33610785 2021
16
Growth Characteristics of Rickettsia Species LON Strains Closely Related to Rickettsia japonica Isolated from Haemaphysalis longicornis Ticks in Mouse Derived L929 and Human-Derived THP-1 Host Cell Lines. 62
32863353 2021
17
Predictive variables for hemodialysis and death in Japanese spotted fever, and the association between distance from rivers and incidence. 62
33011438 2021
18
Spotted fever group rickettsiae (SFGR) detection in ticks following reported human case of Japanese spotted fever in Niigata Prefecture, Japan. 62
33510192 2021
19
Associations between Japanese spotted fever (JSF) cases and wildlife distribution on the Boso Peninsula, Central Japan (2006-2017). 62
33012734 2020
20
Impact of C-Reactive Protein Levels on Differentiating of Severe Fever With Thrombocytopenia Syndrome From Japanese Spotted Fever. 62
33204759 2020
21
Japanese spotted fever. 62
31851356 2020
22
Case of Japanese spotted fever infected 2 consecutive years. 62
32483854 2020
23
Preliminary Evaluation of Human Personal Protective Measures Against the Nymphal Stage of the Asian Longhorned Tick (Acari: Ixodidae). 62
32073128 2020
24
Japanese Spotted Fever with Hemophagocytic Lymphohistiocytosis. 62
31645532 2020
25
In vitro evaluation of minimum inhibitory concentration of several antibacterial agents against Rickettsia japonica using a plaque reduction assay system. 62
31186196 2019
26
Japanese Spotted Fever: A Rare Cause of Arthritis. 62
30918201 2019
27
Diversity of spotted fever group rickettsiae and their association with host ticks in Japan. 62
30728409 2019
28
Genomic Features of Rickettsia heilongjiangensis Revealed by Intraspecies Comparison and Detailed Comparison With Rickettsia japonica. 62
31866968 2019
29
Case Report: Concurrent Sympatric Scrub Typhus and Japanese Spotted Fever in Japan. 62
30298801 2018
30
Japanese Spotted Fever in Eastern China, 2013. 62
30334711 2018
31
Comparison of positive ratio for red meat-specific immunoglobulin E between endemic and non-endemic area for Japanese spotted fever in Mie Prefecture, Japan. 62
29722440 2018
32
Rickettsia japonica Infections in Humans, Zhejiang Province, China, 2015. 62
30334710 2018
33
Japanese spotted fever. 62
29660067 2018
34
Distinguishing Japanese Spotted Fever and Scrub Typhus, Central Japan, 2004- 2015. 62
30124190 2018
35
Important Clinical Features of Japanese Spotted Fever. 62
29968555 2018
36
Distribution of tick-borne diseases in Japan: Past patterns and implications for the future. 62
29685854 2018
37
Serological Cross-Reactivity among Orientia tsutsugamushi Serotypes but Not with Rickettsia japonica in Japan. 62
30274470 2018
38
Evaluation of Diagnostic Assay for Rickettsioses Using Duplex Real-Time PCR in Multiple Laboratories in Japan. 62
29709963 2018
39
Two cases of Japanese spotted fever infected in Rokko mountain near urban area of southern Hyogo Prefecture. 62
29315729 2018
40
Case Report: Family Cluster of Japanese Spotted Fever. 62
29363442 2018
41
Prediction of Disseminated Intravascular Coagulation by Liver Function Tests in Patients with Japanese Spotted Fever. 62
29021432 2018
42
Geographical Distribution of Japanese Spotted Fever and Tsutsugamushi Disease in Japan - Possible Effect of Environmental Temperature. 62
28250253 2017
43
Extremely Low Genomic Diversity of Rickettsia japonica Distributed in Japan. 62
28057731 2017
44
Haemaphysalis longicornis tick bites are a possible cause of red meat allergy in Japan. 62
26551325 2016
45
[Severe Japanese Spotted Fever Complicated by Acute Respiratory Failure in Kobe City]. 62
27197438 2016
46
Improvement in early diagnosis of Japanese spotted fever by using a novel Rick PCR system. 62
26130479 2015
47
[Intravenous Minocycline and Levofloxacin for Treatment of Two Cases of Japanese Spotted Fever]. 62
26630793 2015
48
[Clinical Manifestations of Japanese Spotted Fever: Multi-institution Study in Endemic Areas in Japan]. 62
26554228 2015
49
Detection of rickettsial DNA in ticks and wild boars in Kyoto City, Japan. 62
25298315 2015
50
Significantly higher cytokine and chemokine levels in patients with Japanese spotted fever than in those with Tsutsugamushi disease. 62
24671792 2014

Variations for Japanese Spotted Fever

Expression for Japanese Spotted Fever

Search GEO for disease gene expression data for Japanese Spotted Fever.

Pathways for Japanese Spotted Fever

GO Terms for Japanese Spotted Fever

Sources for Japanese Spotted Fever

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
Content
Loading form....