MCID: JWC001
MIFTS: 21

Jaw Cancer

Categories: Bone diseases, Cancer diseases, Oral diseases

Aliases & Classifications for Jaw Cancer

MalaCards integrated aliases for Jaw Cancer:

Name: Jaw Cancer 12 15 17
Jaw Neoplasms 43 71
Neoplasm of Jaw 12
Cancer of Jaw 71
Jaw Neoplasm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:1862
MeSH 43 D007573
UMLS 71 C0022364 C0751255

Summaries for Jaw Cancer

Disease Ontology : 12 A bone cancer and jaw disease that is located in the jaw and results in a swollen jaw, results in numbness or a tingling sensation in jaw, and results in an abnormal growth of the jaw bone.

MalaCards based summary : Jaw Cancer, also known as jaw neoplasms, is related to maxillary cancer and mandibular cancer. An important gene associated with Jaw Cancer is AGFG2 (ArfGAP With FG Repeats 2). The drug Denosumab has been mentioned in the context of this disorder. Affiliated tissues include bone and tongue.

Related Diseases for Jaw Cancer

Diseases related to Jaw Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 maxillary cancer 28.8 PROM2 PCBP4 GRHL1 GNB1L EPPK1 CLCA2
2 mandibular cancer 11.1
3 myofibroma 9.8
4 medulloblastoma 9.8
5 cerebellar medulloblastoma 9.8

Graphical network of the top 20 diseases related to Jaw Cancer:



Diseases related to Jaw Cancer

Symptoms & Phenotypes for Jaw Cancer

Drugs & Therapeutics for Jaw Cancer

Drugs for Jaw Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Denosumab Approved 615258-40-7

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Survey of Oncology Practitioners Prescribing XGEVA® in Europe to Evaluate Their Knowledge of XGEVA® Summary of Product Characteristics Pertaining to Osteonecrosis of the Jaw Completed NCT01998607
2 Quality of Life in Patients Treated for Tongue and/or Jaw Neoplasia Before and After Speech Therapy: a Randomized Clinical Trial Completed NCT04126226
3 POPULATION PHARMACOMETRICS FOR ASSESSING RISK OF BISPHOSPHONATE-RELATED OSTEONECROSIS OF THE JAW (BRONJ) Withdrawn NCT02069340 zoledronic acid

Search NIH Clinical Center for Jaw Cancer

Cochrane evidence based reviews: jaw neoplasms

Genetic Tests for Jaw Cancer

Anatomical Context for Jaw Cancer

MalaCards organs/tissues related to Jaw Cancer:

40
Bone, Tongue

Publications for Jaw Cancer

Articles related to Jaw Cancer:

(show all 28)
# Title Authors PMID Year
1
Analysis of 46 cases of malignant jaw tumours in Calabar, Nigeria. 61
26759506 2015
2
[Digital and three-demention print technique in reconstruction for complex defect after resection of jaw neoplasms]. 61
26695798 2015
3
Dental extraction as a risk factor for bisphosphonate related osteonecrosis of the jaw in cancer patients: an update. 61
24073539 2013
4
Etiopathogenesis of Burkitt's lymphoma: a lesson from a BL-like in CD1 mouse immune to Plasmodium yoelii yoelii. 61
21740585 2011
5
Assessment of the quality of life in patients with oral cavity and jaw cancer in three regions of Bulgaria. 61
17918295 2007
6
[Cancer of the jaw and oral cavity in the Syrian Arab Republic: an epidemiological study]. 61
16602446 2005
7
Metastases to the human mandible. 61
10768014 1999
8
Comparative study of inhibitory effects by murine interferon gamma and a new bisphosphonate (alendronate) in hypercalcemic, nude mice bearing human tumor (LJC-1-JCK). 61
7522963 1994
9
Paraneoplastic syndrome of hypercalcemia and leukocytosis caused by squamous carcinoma cells (T3M-1) producing parathyroid hormone-related protein, interleukin 1 alpha, and granulocyte colony-stimulating factor. 61
2474371 1989
10
Differential diagnosis in dentistry: jaw neoplasms. 61
3216126 1988
11
[Functional efficiency of the sense of taste in patients after the excision of mouth and jaw neoplasms]. 61
6581925 1983
12
Association of hypercalcemia with tumors producing colony-stimulating factor(s). 61
6600966 1983
13
Giant complex odontoma of the maxillary antrum. A case report. 61
6845080 1983
14
[Odontogenic jaw neoplasms. Classification, pathogenesis and incidence]. 61
902592 1977
15
[Changes in the activity of glucose-6-phosphate dehydrogenase and the content of reduced glutathione in erythrocytes of patients with jaw neoplasms]. 61
265846 1977
16
[Effect of apernyl in the treatment of complications of surgery for jaw neoplasms]. 61
802030 1976
17
Epithelial origin of some jaw neoplasms. 61
4523929 1974
18
[Surgical management of jaw neoplasms and neoplasms of surrounding soft tissue including plastic and reconstructive measures. Report of the continuous education performance of the BDZ in Salzburg and Meran]. 61
4513043 1973
19
[Secondary jaw cancer]. 61
4519826 1973
20
[Prosthetic reconstruction in operated jaw neoplasms]. 61
4565699 1972
21
[Results of treatment of jaw cancer in the light of material from the Department of Dental Surgery, Medical Academy in Warsaw in the years 1955-1969]. 61
5285671 1971
22
[Intratracheal anesthesia in operations of jaw neoplasms]. 61
5256113 1969
23
[Certain surgical problems in advanced oral and jaw neoplasms]. 61
5256128 1969
24
[Demonstration of tumor cells from mouth and jaw neoplasms by cytological methods]. 61
5245642 1968
25
[Surgery of primitive jaw neoplasms of dental origin]. 61
4921512 1968
26
[Histopathology of jaw neoplasms of dental origin]. 61
5221664 1966
27
[Contribution to the knowledge on odontogenic jaw neoplasms. Presentation of 7 clinical cases]. 61
5230012 1965
28
[Technique of surgery of large jaw neoplasms]. 61
12988866 1952

Variations for Jaw Cancer

Expression for Jaw Cancer

Search GEO for disease gene expression data for Jaw Cancer.

Pathways for Jaw Cancer

GO Terms for Jaw Cancer

Sources for Jaw Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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