MCID: JWC001
MIFTS: 22

Jaw Cancer

Categories: Bone diseases, Cancer diseases, Oral diseases
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Aliases & Classifications for Jaw Cancer

MalaCards integrated aliases for Jaw Cancer:

Name: Jaw Cancer 11 14 16
Jaw Neoplasms 43 71
Neoplasm of Jaw 11
Cancer of Jaw 71
Jaw Neoplasm 11

Classifications:



External Ids:

Disease Ontology 11 DOID:1862
MeSH 43 D007573
SNOMED-CT 68 126634001
UMLS 71 C0022364 C0751255

Summaries for Jaw Cancer

Disease Ontology: 11 A bone cancer and jaw disease that is located in the jaw and results in a swollen jaw, results in numbness or a tingling sensation in jaw, and results in an abnormal growth of the jaw bone.

MalaCards based summary: Jaw Cancer, also known as jaw neoplasms, is related to maxillary cancer and mandibular cancer. An important gene associated with Jaw Cancer is AGFG2 (ArfGAP With FG Repeats 2). Affiliated tissues include bone and tongue.

Related Diseases for Jaw Cancer

Diseases related to Jaw Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 maxillary cancer 28.9 TAS2R60 TAS2R5 SESN1 PROM2 PCBP4 GRHL1
2 mandibular cancer 11.0
3 medulloblastoma 9.9
4 ewing sarcoma 9.9
5 cerebellar medulloblastoma 9.9
6 islet cell tumor 9.9
7 myofibroma 9.9

Graphical network of the top 20 diseases related to Jaw Cancer:



Diseases related to Jaw Cancer

Symptoms & Phenotypes for Jaw Cancer

Drugs & Therapeutics for Jaw Cancer

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Jaw Reconstruction With Printed Titanium and Free Tissue Transfer Unknown status NCT03905005
2 Quality of Life in Patients Treated for Tongue and/or Jaw Neoplasia Before and After Speech Therapy: a Randomized Clinical Trial Completed NCT04126226
3 Simultaneous Dental Implant in Free Vascularized Bone Flaps for Jaw Reconstruction Using Patient-specific Surgical Guides and Titanium Plates: a Pilot Study Recruiting NCT05405179

Search NIH Clinical Center for Jaw Cancer

Cochrane evidence based reviews: jaw neoplasms

Genetic Tests for Jaw Cancer

Anatomical Context for Jaw Cancer

Organs/tissues related to Jaw Cancer:

MalaCards : Bone, Tongue

Publications for Jaw Cancer

Articles related to Jaw Cancer:

(show all 17)
# Title Authors PMID Year
1
Enhanced basal autophagy supports ameloblastoma-derived cell survival and reactivation. 62
30465934 2019
2
Management of Odontogenic Fibromyxoma in Pediatric Nigerian Patients: A Review of 8 Cases. 62
27057387 2015
3
Dental extraction as a risk factor for bisphosphonate related osteonecrosis of the jaw in cancer patients: an update. 62
24073539 2013
4
Etiopathogenesis of Burkitt's lymphoma: a lesson from a BL-like in CD1 mouse immune to Plasmodium yoelii yoelii. 62
21740585 2011
5
Assessment of the quality of life in patients with oral cavity and jaw cancer in three regions of Bulgaria. 62
17918295 2007
6
Testing your diagnostic skills. Case No. 1: a relatively rare jaw neoplasm called a myofibroma. 62
17708027 2006
7
[Cancer of the jaw and oral cavity in the Syrian Arab Republic: an epidemiological study]. 62
16602446 2005
8
Comparative study of inhibitory effects by murine interferon gamma and a new bisphosphonate (alendronate) in hypercalcemic, nude mice bearing human tumor (LJC-1-JCK). 62
7522963 1994
9
Paraneoplastic syndrome of hypercalcemia and leukocytosis caused by squamous carcinoma cells (T3M-1) producing parathyroid hormone-related protein, interleukin 1 alpha, and granulocyte colony-stimulating factor. 62
2474371 1989
10
Small round cell neoplasm of jaw in a patient with medulloblastoma. 62
2926552 1989
11
Association of hypercalcemia with tumors producing colony-stimulating factor(s). 62
6600966 1983
12
[Epithelioma cuniculatum an unusual form of mouth and jaw neoplasm]. 62
266444 1977
13
[Secondary jaw cancer]. 62
4519826 1973
14
[Results of treatment of jaw cancer in the light of material from the Department of Dental Surgery, Medical Academy in Warsaw in the years 1955-1969]. 62
5285671 1971
15
Lower jaw cancer; Healing with loss of bone and integumentary substance by radionecrosis; refection far bipedicular temporoparietal flap and iliac bone graft. 62
18934337 1948
16
Lower jaw cancer; Healing with loss of bone and integumentary substance by radionecrosis repair by bipedicular temporo-pariallial flap and iliac bone graft. 62
18906332 1948
17
Treatment of upper jaw cancer. 62
20991064 1946

Variations for Jaw Cancer

Expression for Jaw Cancer

Search GEO for disease gene expression data for Jaw Cancer.

Pathways for Jaw Cancer

GO Terms for Jaw Cancer

Biological processes related to Jaw Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 detection of chemical stimulus involved in sensory perception of bitter taste GO:0001580 9.13 TAS2R60 TAS2R5
2 sensory perception of taste GO:0050909 8.62 TAS2R60 TAS2R5

Molecular functions related to Jaw Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 bitter taste receptor activity GO:0033038 8.8 TAS2R60 TAS2R5

Sources for Jaw Cancer

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 24-Oct-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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