MCID: JJN007
MIFTS: 29

Jejunal Adenocarcinoma

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Jejunal Adenocarcinoma

MalaCards integrated aliases for Jejunal Adenocarcinoma:

Name: Jejunal Adenocarcinoma 12 15 73

Classifications:



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Disease Ontology 12 DOID:0050926
UMLS 73 C4072935

Summaries for Jejunal Adenocarcinoma

Disease Ontology : 12 A jejunal cancer that is located in the jejunum and has material basis in epithelial tissue that has glandular origin.

MalaCards based summary : Jejunal Adenocarcinoma is related to intestinal obstruction and cystic basal cell carcinoma. An important gene associated with Jejunal Adenocarcinoma is KRT7 (Keratin 7), and among its related pathways/superpathways are DNA Damage and Integrated Breast Cancer Pathway. Affiliated tissues include the jejunum, colon and small intestine, and related phenotypes are cellular and neoplasm

Related Diseases for Jejunal Adenocarcinoma

Diseases related to Jejunal Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 132)
# Related Disease Score Top Affiliating Genes
1 intestinal obstruction 30.0 CDX2 KRT7
2 cystic basal cell carcinoma 10.7 KRT20 KRT7
3 seminal vesicle adenocarcinoma 10.7 KRT20 KRT7
4 transverse colon cancer 10.7 KRT20 KRT7
5 ovarian large-cell neuroendocrine carcinoma 10.7 KRT20 KRT7
6 eyelid neoplasm 10.7 KRT20 KRT7
7 malignant syringoma 10.7 KRT20 KRT7
8 krukenberg carcinoma 10.7 KRT20 KRT7
9 large intestine adenocarcinoma 10.7 KRT20 KRT7
10 linitis plastica 10.7 KRT20 KRT7
11 lung acinar adenocarcinoma 10.7 KRT20 KRT7
12 small cell carcinoma of the bladder 10.7 KRT20 KRT7
13 ovary neuroendocrine neoplasm 10.7 CDX2 KRT7
14 adenoid squamous cell carcinoma 10.7 KRT20 KRT7
15 eccrine sweat gland neoplasm 10.7 KRT20 KRT7
16 mucinous adenofibroma 10.7 CDX2 KRT7
17 anus adenocarcinoma 10.7 CDX2 KRT7
18 vulval paget's disease 10.7 KRT20 KRT7
19 bile duct cystadenocarcinoma 10.7 KRT20 KRT7
20 intratubular embryonal carcinoma 10.7 KRT20 KRT7
21 meibomian cyst 10.7 KRT20 KRT7
22 bladder lymphoma 10.7 KRT20 KRT7
23 papillary serous adenocarcinoma 10.7 KRT20 KRT7
24 epithelial predominant wilms' tumor 10.7 CDX2 KRT7
25 medulloepithelioma 10.7 KRT20 KRT7
26 glycogen-rich clear cell breast carcinoma 10.7 KRT20 KRT7
27 renal pelvis carcinoma 10.7 KRT20 KRT7
28 paget disease, extramammary 10.7 KRT20 KRT7
29 bronchiolo-alveolar adenocarcinoma 10.7 CDX2 KRT7
30 mucinous cystadenocarcinoma 10.6 KRT20 KRT7
31 lymphoepithelioma-like carcinoma 10.6 KRT20 KRT7
32 nasal cavity adenocarcinoma 10.6 CDX2 KRT7
33 mucinous ovarian cystadenoma 10.6 CDX2 KRT7
34 dermoid cyst 10.6 KRT20 KRT7
35 anal canal adenocarcinoma 10.6 CDX2 KRT7
36 infiltrative basal cell carcinoma 10.6 KRT20 KRT7
37 immune system organ benign neoplasm 10.6 KRT20 KRT7
38 thymus lipoma 10.6 KRT20 KRT7
39 cystadenofibroma 10.6 KRT20 KRT7
40 inverted papilloma 10.6 KRT20 KRT7
41 ovarian cystic teratoma 10.6 KRT20 KRT7
42 villous adenoma 10.6 CDX2 KRT20
43 pancreatic mucinous cystadenoma 10.6 KRT20 KRT7
44 biliary tract neoplasm 10.6 CDX2 KRT7
45 large cell neuroendocrine carcinoma 10.6 KRT20 KRT7
46 duodenum cancer 10.6 CDX2 KRT7
47 mammary paget's disease 10.6 KRT20 KRT7
48 benign mesothelioma 10.6 KRT20 KRT7
49 gastric tubular adenocarcinoma 10.5 CDX2 KRT7
50 cervical adenoma malignum 10.5 KRT7 STK11

Graphical network of the top 20 diseases related to Jejunal Adenocarcinoma:



Diseases related to Jejunal Adenocarcinoma

Symptoms & Phenotypes for Jejunal Adenocarcinoma

MGI Mouse Phenotypes related to Jejunal Adenocarcinoma:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.56 STK11 TNFRSF25 WWOX CCND1 CDX2 KRT7
2 neoplasm MP:0002006 9.1 WWOX CCND1 CDX2 MSH6 SMUG1 STK11

Drugs & Therapeutics for Jejunal Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Jejunal Adenocarcinoma

Genetic Tests for Jejunal Adenocarcinoma

Anatomical Context for Jejunal Adenocarcinoma

The Foundational Model of Anatomy Ontology organs/tissues related to Jejunal Adenocarcinoma:

19
The Jejunum

MalaCards organs/tissues related to Jejunal Adenocarcinoma:

41
Colon, Small Intestine

Publications for Jejunal Adenocarcinoma

Articles related to Jejunal Adenocarcinoma:

(show all 29)
# Title Authors Year
1
Primary Jejunal adenocarcinoma - An unsuspected culprit. ( 29540890 )
2018
2
A Challenging Diagnosis of Jejunal Adenocarcinoma in a Celiac Patient: Case Report and Systematic Review of the Literature. ( 29253057 )
2017
3
Primary Jejunal Adenocarcinoma Presenting as Bilateral Ovarian Metastasis. ( 29317945 )
2017
4
Computed Tomographic presentation of obstructive jejunal adenocarcinoma associated with celiac disease and incomplete intestinal malrotation. ( 26670410 )
2016
5
Adult jejunojejunal intussusception in the face of jejunal adenocarcinoma: two infrequently encountered entities. ( 26961563 )
2016
6
Jejunal adenocarcinoma with cutaneous metastasis. ( 26436979 )
2015
7
Jejunal adenocarcinoma with concomitant enterolith presenting as acute intestinal obstruction. ( 24717991 )
2014
8
Gastrointestinal tract obstruction due to jejunal adenocarcinoma--case report. ( 24988236 )
2014
9
Surgical management of small intestinal intussusception associated with jejunal adenocarcinoma in a dairy cow. ( 25530282 )
2014
10
Primary jejunal adenocarcinoma incidentally diagnosed on positron emission tomography/computed tomography in a patient with metastatic colorectal cancer: suspicion of Lynch syndrome and effect on therapeutic management. ( 23341528 )
2013
11
Jejunal adenocarcinoma-a case report with review. ( 24426522 )
2013
12
Challenging diagnosis of a jejunal adenocarcinoma with ovarian metastasis: report of an unusual case. ( 23580681 )
2013
13
Jejunal adenocarcinoma: an elusive diagnosis. ( 22942611 )
2011
14
Familial adenomatous polyposis with synchronous invasive colonic carcinomas and metastatic jejunal adenocarcinoma in a Nigerian male. ( 21234258 )
2010
15
Atypical identification of Lynch syndrome by immunohistochemistry and microsatellite instability analysis on jejunal adenocarcinoma. ( 20379851 )
2010
16
Intussusception and volvulus secondary to jejunal adenocarcinoma in an adult Nigerian male: a case report. ( 21220868 )
2010
17
Peutz-Jeghers syndrome and duodeno-jejunal adenocarcinoma--therapeutic implications. ( 20082550 )
2009
18
A case of jejunal adenocarcinoma diagnosed by preoperative double balloon enteroscopy. ( 20431766 )
2009
19
Preoperative diagnosis of jejunal adenocarcinoma--a case report. ( 18404799 )
2008
20
Oxaliplatin/5-fluorouracil/leucovorin (FOLFOX4) regimen as an adjuvant chemotherapy in the treatment of advanced jejunal adenocarcinoma: a report of 2 cases. ( 18836281 )
2008
21
Jejunojejunal intussusception by a known jejunal adenocarcinoma. ( 18815635 )
2008
22
Jejunal adenocarcinoma: still an elusive diagnosis. Case report and review of the literature. ( 18709788 )
2008
23
Primary jejunal adenocarcinoma as part of multiple primary cancers of the digestive tract. ( 18397495 )
2008
24
Jejunal adenocarcinoma: a rare cause of chronic anemia in children. ( 16385262 )
2006
25
Jejunal adenocarcinoma. ( 15758917 )
2005
26
FDG PET and gallium scintigraphy for diagnosis of an advanced jejunal adenocarcinoma with distant metastases. ( 15545894 )
2004
27
Poorly differentiated jejunal adenocarcinoma in a patient with coeliac disease: a case report. ( 12239769 )
2002
28
Jejunal adenocarcinoma presenting as a primary ovarian carcinoma. ( 10926813 )
2000
29
Obstructive jejunal adenocarcinoma in the Muir-Torre syndrome. ( 8302390 )
1993

Variations for Jejunal Adenocarcinoma

Expression for Jejunal Adenocarcinoma

Search GEO for disease gene expression data for Jejunal Adenocarcinoma.

Pathways for Jejunal Adenocarcinoma

Pathways related to Jejunal Adenocarcinoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.6 CCND1 MSH6 WWOX
2 10.99 CCND1 MSH6 STK11

GO Terms for Jejunal Adenocarcinoma

Cellular components related to Jejunal Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 transcriptional repressor complex GO:0017053 8.62 CCND1 CDX2

Biological processes related to Jejunal Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 apoptotic process GO:0006915 9.46 KRT20 STK11 TNFRSF25 WWOX
2 intrinsic apoptotic signaling pathway by p53 class mediator GO:0072332 8.96 STK11 WWOX
3 cellular response to DNA damage stimulus GO:0006974 8.92 CCND1 MSH6 SMUG1 STK11

Sources for Jejunal Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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