MCID: JJN003
MIFTS: 30

Jejunal Cancer

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Jejunal Cancer

MalaCards integrated aliases for Jejunal Cancer:

Name: Jejunal Cancer 12 15
Malignant Neoplasm of Jejunum 12 73
Jejunal Neoplasms 44 73
Jejunal Neoplasm 12 15
Malignant Tumor of Jejunum 12
Neoplasm of Jejunum 12
Tumor of Jejunum 12
Jejunal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13499 DOID:3218
ICD10 33 C17.1
ICD9CM 35 152.1
MeSH 44 D007580
NCIt 50 C8401

Summaries for Jejunal Cancer

MalaCards based summary : Jejunal Cancer, also known as malignant neoplasm of jejunum, is related to jejunal adenocarcinoma and cribriform carcinoma. An important gene associated with Jejunal Cancer is KRT7 (Keratin 7). The drugs Liver Extracts and Cola have been mentioned in the context of this disorder. Affiliated tissues include small intestine, liver and skin, and related phenotype is cellular.

Related Diseases for Jejunal Cancer

Diseases related to Jejunal Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 48)
# Related Disease Score Top Affiliating Genes
1 jejunal adenocarcinoma 11.0
2 cribriform carcinoma 10.3 KIT KRT7
3 malignant mixed mullerian tumor 10.3 KIT KRT7
4 adenoid basal cell carcinoma 10.3 KIT KRT7
5 intratubular embryonal carcinoma 10.3 KIT KRT7
6 malignant leydig cell tumor 10.2 KIT KRT7
7 kidney benign neoplasm 10.2 KIT KRT7
8 pleomorphic carcinoma 10.2 KIT KRT7
9 dermoid cyst 10.2 KIT KRT7
10 mixed cell type cancer 10.2 KIT KRT7
11 necrotizing sialometaplasia 10.2 KIT KRT7
12 large cell neuroendocrine carcinoma 10.2 KIT KRT7
13 spindle cell synovial sarcoma 10.2 KIT KRT7
14 renal oncocytoma 10.2 KIT KRT7
15 ovarian brenner tumor 10.2 KIT KRT7
16 organ system benign neoplasm 10.2 KIT KRT7
17 integumentary system cancer 10.1 KIT KRT7
18 small cell carcinoma 10.1 KIT KRT7
19 oncocytoma 10.1 KIT KRT7
20 chromophobe renal cell carcinoma 10.1 KIT KRT7
21 merkel cell carcinoma 10.1 KIT KRT7
22 thymus cancer 10.1 KIT KRT7
23 sarcoma, synovial 10.0 KIT KRT7
24 teratoma 10.0 KIT KRT7
25 renal cell carcinoma, papillary, 1 10.0 KIT KRT7
26 cecal benign neoplasm 9.9 KRT7 MUTYH
27 familial adenomatous polyposis 9.9
28 duodenum cancer 9.9 KRT7 MUTYH
29 small intestine cancer 9.8 KRT7 MUTYH
30 cell type cancer 9.8 KIT KRT7
31 cell type benign neoplasm 9.8 KRT7 MUTYH
32 gastrointestinal stromal tumor 9.7
33 angiodysplasia 9.7
34 smooth muscle tumor 9.7
35 intestinal obstruction 9.7
36 adenoid cystic carcinoma 9.7 KIT KRT7
37 esophagitis 9.6
38 lynch syndrome 9.6
39 mutyh-associated polyposis 9.6
40 desmoid tumor 9.6
41 squamous cell carcinoma 9.6
42 intestinal perforation 9.6
43 rectal neoplasm 9.6 KRT7 MUTYH
44 small cell cancer of the lung 9.4 KIT KRT7
45 autosomal genetic disease 9.4 MUTYH WRN
46 gastrointestinal system benign neoplasm 9.3 KIT KRT7 MUTYH
47 gastrointestinal system cancer 9.3 KIT KRT7 MUTYH
48 endometrial cancer 8.9 KIT KRT7 MUTYH

Comorbidity relations with Jejunal Cancer via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Intestinal Obstruction

Graphical network of the top 20 diseases related to Jejunal Cancer:



Diseases related to Jejunal Cancer

Symptoms & Phenotypes for Jejunal Cancer

MGI Mouse Phenotypes related to Jejunal Cancer:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 GAN KIT KRT7 MUTYH WRN

Drugs & Therapeutics for Jejunal Cancer

Drugs for Jejunal Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 6)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts Phase 1
2 Cola Nutraceutical Phase 1
3
Menthol Approved 2216-51-5 16666
4 Fluorodeoxyglucose F18
5 Antibodies
6 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of TCM Syndrome of Hepatocellular Carcinoma and Colorectal Cancer Based on System Science Recruiting NCT03189992 Phase 1 Bushen-Jianpi Dedoction;cinobufotalin injection
2 Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality Completed NCT02378337
3 Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer Terminated NCT00899132

Search NIH Clinical Center for Jejunal Cancer

Cochrane evidence based reviews: jejunal neoplasms

Genetic Tests for Jejunal Cancer

Anatomical Context for Jejunal Cancer

MalaCards organs/tissues related to Jejunal Cancer:

41
Small Intestine, Liver, Skin, Colon

Publications for Jejunal Cancer

Articles related to Jejunal Cancer:

(show all 15)
# Title Authors Year
1
A case of Lynch syndrome with advanced jejunal cancer. ( 25373375 )
2014
2
Jejunal Cancer with WRN Mutation Identified from Next-Generation Sequencing: A Case Study and Minireview. ( 25018888 )
2014
3
Successful treatment of primary jejunal cancer after esophageal and colon cancer resection. ( 24620639 )
2013
4
Multiple jejunal cancers resulting from combination of germline APC and MLH1 mutations. ( 22886683 )
2012
5
Response to jejunal cancer in patients with familial adenomatous polyposis. ( 21182984 )
2011
6
Jejunal cancer in patients with familial adenomatous polyposis. ( 20621624 )
2010
7
Jejunal cancer in patients with familial adenomatous polyposis. ( 20399906 )
2010
8
Jejunal cancer detected after a resection of bilateral ovarian metastasis: report of a case. ( 21046510 )
2010
9
Aggressive phenotype of MYH-associated polyposis with jejunal cancer and intra-abdominal desmoid tumor: report of a case. ( 19404084 )
2009
10
A case of primary jejunal cancer diagnosed by preoperative small intestinal endoscopy. ( 21318964 )
2008
11
Education and imaging. Gastrointestinal: metallic stent for an obstructing jejunal cancer. ( 17074030 )
2006
12
Huge ovarian metastasis from jejunal cancer occurring immediately after initial operation. ( 15816449 )
2005
13
Primary jejunal cancer. ( 16246696 )
2005
14
Two sisters with coeliac disease and jejunal cancer: just a coincidence? ( 8446219 )
1993
15
Jejunal cancer; a case report. ( 20992565 )
1946

Variations for Jejunal Cancer

Expression for Jejunal Cancer

Search GEO for disease gene expression data for Jejunal Cancer.

Pathways for Jejunal Cancer

GO Terms for Jejunal Cancer

Biological processes related to Jejunal Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 base-excision repair GO:0006284 8.62 MUTYH WRN

Sources for Jejunal Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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