MCID: JJN003
MIFTS: 28

Jejunal Cancer

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Jejunal Cancer

MalaCards integrated aliases for Jejunal Cancer:

Name: Jejunal Cancer 12 15
Malignant Neoplasm of Jejunum 12 73
Jejunal Neoplasms 44 73
Jejunal Neoplasm 12 15
Malignant Tumor of Jejunum 12
Neoplasm of Jejunum 12
Tumor of Jejunum 12
Jejunal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:13499 DOID:3218
ICD10 33 C17.1
ICD9CM 35 152.1
MeSH 44 D007580
SNOMED-CT 68 93846004
NCIt 50 C8401

Summaries for Jejunal Cancer

MalaCards based summary : Jejunal Cancer, also known as malignant neoplasm of jejunum, is related to jejunal adenocarcinoma and ceruminoma. An important gene associated with Jejunal Cancer is KRT7 (Keratin 7). The drugs Liver Extracts and Cola have been mentioned in the context of this disorder. Affiliated tissues include colon, small intestine and lung, and related phenotype is cellular.

Related Diseases for Jejunal Cancer

Diseases related to Jejunal Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 45)
# Related Disease Score Top Affiliating Genes
1 jejunal adenocarcinoma 11.1
2 ceruminoma 10.1 KIT KRT7
3 intratubular embryonal carcinoma 10.1 KIT KRT7
4 cribriform carcinoma 10.1 KIT KRT7
5 adenoid basal cell carcinoma 10.1 KIT KRT7
6 malignant leydig cell tumor 10.1 KIT KRT7
7 warthin tumor 10.1 KIT KRT7
8 dermoid cyst 10.1 KIT KRT7
9 prostatic acinar adenocarcinoma 10.1 KIT KRT7
10 necrotizing sialometaplasia 10.1 KIT KRT7
11 mixed cell type cancer 10.1 KIT KRT7
12 large cell neuroendocrine carcinoma 10.1 KIT KRT7
13 tonsil cancer 10.1 KIT KRT7
14 renal oncocytoma 10.1 KIT KRT7
15 oncocytoma 10.1 KIT KRT7
16 oropharynx cancer 10.0 KIT KRT7
17 ovarian brenner tumor 10.0 KIT KRT7
18 dysgerminoma 10.0 KIT KRT7
19 cavernous hemangioma 10.0 KIT KRT7
20 adenosquamous carcinoma 10.0 KIT KRT7
21 small cell carcinoma 10.0 KIT KRT7
22 chromophobe renal cell carcinoma 10.0 KIT KRT7
23 merkel cell carcinoma 10.0 KIT KRT7
24 carcinosarcoma 10.0 KIT KRT7
25 thymus cancer 10.0 KIT KRT7
26 sarcoma, synovial 10.0 KIT KRT7
27 teratoma 10.0 KIT KRT7
28 familial adenomatous polyposis 10.0
29 duodenum cancer 10.0 KRT7 MUTYH
30 cell type benign neoplasm 9.9 KRT7 MUTYH
31 renal cell carcinoma, papillary, 1 9.9 KIT KRT7
32 rectal neoplasm 9.9 KRT7 MUTYH
33 small cell cancer of the lung 9.8 KIT KRT7
34 gastrointestinal stromal tumor 9.8
35 angiodysplasia 9.8
36 smooth muscle tumor 9.8
37 intestinal obstruction 9.8
38 gastrointestinal system cancer 9.8 KIT KRT7 MUTYH
39 autosomal genetic disease 9.8 MUTYH WRN
40 lynch syndrome 9.7
41 mutyh-associated polyposis 9.7
42 desmoid tumor 9.7
43 squamous cell carcinoma 9.7
44 intestinal perforation 9.7
45 endometrial cancer 9.6 KIT KRT7 MUTYH

Comorbidity relations with Jejunal Cancer via Phenotypic Disease Network (PDN):


Active Peptic Ulcer Disease Intestinal Obstruction

Graphical network of the top 20 diseases related to Jejunal Cancer:



Diseases related to Jejunal Cancer

Symptoms & Phenotypes for Jejunal Cancer

MGI Mouse Phenotypes related to Jejunal Cancer:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 cellular MP:0005384 9.02 GAN KIT KRT7 MUTYH WRN

Drugs & Therapeutics for Jejunal Cancer

Drugs for Jejunal Cancer (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts Phase 1
2 Cola Phase 1
3 Fluorodeoxyglucose F18
4 Immunoglobulins
5 Antibodies

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of TCM Syndrome of Hepatocellular Carcinoma and Colorectal Cancer Based on System Science Recruiting NCT03189992 Phase 1 Bushen-Jianpi Dedoction;cinobufotalin injection
2 Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality Completed NCT02378337
3 Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer Terminated NCT00899132

Search NIH Clinical Center for Jejunal Cancer

Cochrane evidence based reviews: jejunal neoplasms

Genetic Tests for Jejunal Cancer

Anatomical Context for Jejunal Cancer

MalaCards organs/tissues related to Jejunal Cancer:

41
Colon, Small Intestine, Lung, Tonsil, Prostate, Smooth Muscle, Thymus

Publications for Jejunal Cancer

Articles related to Jejunal Cancer:

(show all 14)
# Title Authors Year
1
A case of Lynch syndrome with advanced jejunal cancer. ( 25373375 )
2014
2
Jejunal Cancer with WRN Mutation Identified from Next-Generation Sequencing: A Case Study and Minireview. ( 25018888 )
2014
3
Successful treatment of primary jejunal cancer after esophageal and colon cancer resection. ( 24620639 )
2013
4
Response to jejunal cancer in patients with familial adenomatous polyposis. ( 21182984 )
2011
5
Jejunal cancer in patients with familial adenomatous polyposis. ( 20621624 )
2010
6
Jejunal cancer in patients with familial adenomatous polyposis. ( 20399906 )
2010
7
Jejunal cancer detected after a resection of bilateral ovarian metastasis: report of a case. ( 21046510 )
2010
8
Aggressive phenotype of MYH-associated polyposis with jejunal cancer and intra-abdominal desmoid tumor: report of a case. ( 19404084 )
2009
9
A case of primary jejunal cancer diagnosed by preoperative small intestinal endoscopy. ( 21318964 )
2008
10
Education and imaging. Gastrointestinal: metallic stent for an obstructing jejunal cancer. ( 17074030 )
2006
11
Huge ovarian metastasis from jejunal cancer occurring immediately after initial operation. ( 15816449 )
2005
12
Primary jejunal cancer. ( 16246696 )
2005
13
Two sisters with coeliac disease and jejunal cancer: just a coincidence? ( 8446219 )
1993
14
Jejunal cancer; a case report. ( 20992565 )
1946

Variations for Jejunal Cancer

Expression for Jejunal Cancer

Search GEO for disease gene expression data for Jejunal Cancer.

Pathways for Jejunal Cancer

GO Terms for Jejunal Cancer

Biological processes related to Jejunal Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 base-excision repair GO:0006284 8.62 MUTYH WRN

Molecular functions related to Jejunal Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 MutLalpha complex binding GO:0032405 8.62 MUTYH WRN

Sources for Jejunal Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....