MCID: JJN002
MIFTS: 35

Jejunal Neoplasm

Categories: Cancer diseases, Gastrointestinal diseases

Aliases & Classifications for Jejunal Neoplasm

MalaCards integrated aliases for Jejunal Neoplasm:

Name: Jejunal Neoplasm 12 15
Neoplasm of Jejunum 12
Tumor of Jejunum 12
Jejunal Tumor 12

Classifications:



External Ids:

Disease Ontology 12 DOID:3218
MeSH 45 D007580
NCIt 51 C8401
UMLS 74 C0022374

Summaries for Jejunal Neoplasm

MalaCards based summary : Jejunal Neoplasm, also known as neoplasm of jejunum, is related to jejunal cancer and carcinoid syndrome. An important gene associated with Jejunal Neoplasm is GAN (Gigaxonin), and among its related pathways/superpathways are Cytoskeletal Signaling and Hematopoietic Stem Cell Differentiation Pathways and Lineage-specific Markers. The drugs Liver Extracts and Cola have been mentioned in the context of this disorder. Affiliated tissues include lung, liver and breast, and related phenotypes are Reduced mammosphere formation and renal/urinary system

Related Diseases for Jejunal Neoplasm

Diseases related to Jejunal Neoplasm via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 327)
# Related Disease Score Top Affiliating Genes
1 jejunal cancer 32.5 GAN KIT KRT7
2 carcinoid syndrome 30.0 CHGA ENO2 SYP
3 gastrointestinal stromal tumor 29.4 CD34 CHGA ENO2 KIT SYP
4 intracranial primitive neuroectodermal tumor 10.4 CHGA ENO2
5 ceruminoma 10.4 KIT KRT7
6 gastric leiomyosarcoma 10.4 ENO2 KIT
7 vaginal benign neoplasm 10.4 CHGA KRT20
8 vaginal adenoma 10.4 CHGA KRT20
9 vaginal tubulovillous adenoma 10.4 CHGA KRT20
10 cystic basal cell carcinoma 10.4 KRT20 KRT7
11 seminal vesicle adenocarcinoma 10.4 KRT20 KRT7
12 transverse colon cancer 10.4 KRT20 KRT7
13 appendix adenocarcinoma 10.4 KRT20 KRT7
14 malignant syringoma 10.4 KRT20 KRT7
15 carotid body cancer 10.4 ENO2 SYP
16 glandular cystitis 10.4 KRT20 KRT7
17 eyelid carcinoma 10.4 KRT20 KRT7
18 krukenberg carcinoma 10.4 KRT20 KRT7
19 lung oat cell carcinoma 10.4 CHGA ENO2
20 malignant sertoli cell tumor 10.4 ENO2 SYP
21 large intestine adenocarcinoma 10.4 KRT20 KRT7
22 cribriform carcinoma 10.4 KIT KRT7
23 linitis plastica 10.4 KRT20 KRT7
24 duodenum adenocarcinoma 10.4 KRT7 MUC6
25 lung acinar adenocarcinoma 10.4 KRT20 KRT7
26 reticular perineurioma 10.4 KIT MUC1
27 ureter small cell carcinoma 10.4 CHGA SYP
28 adenoid basal cell carcinoma 10.4 KIT KRT7
29 esophageal neuroendocrine tumor 10.4 CHGA SYP
30 pilomatrix carcinoma 10.4 ENO2 MUC1
31 adenoid squamous cell carcinoma 10.4 KRT20 KRT7
32 mixed type thymoma 10.4 KIT SYP
33 malignant leydig cell tumor 10.4 KIT KRT7
34 pancreatic somatostatinoma 10.4 ENO2 SYP
35 endocervical carcinoma 10.4 KRT7 MUC6
36 intracranial cysts 10.4 ENO2 MUC1
37 extrahepatic bile duct adenocarcinoma 10.4 ENO2 SYP
38 ovary neuroendocrine neoplasm 10.4 KRT7 SYP
39 tumor of exocrine pancreas 10.4 MUC1 MUC6
40 pancreatic intraductal papillary-mucinous neoplasm 10.4 MUC1 MUC6
41 acute thyroiditis 10.4 CHGA ENO2
42 orbital cancer 10.4 ENO2 SYP
43 vulval paget's disease 10.4 KRT20 KRT7
44 peritoneal serous adenocarcinoma 10.4 CHGA SYP
45 cellular ependymoma 10.4 CHGA SYP
46 primary hepatic neuroendocrine carcinoma 10.4 CHGA SYP
47 mucinous adenofibroma 10.4 KRT7 SYP
48 central nervous system primitive neuroectodermal neoplasm 10.3 ENO2 SYP
49 cerebellum cancer 10.3 ENO2 SYP
50 jejunal adenocarcinoma 10.3 KRT20 KRT7

Graphical network of the top 20 diseases related to Jejunal Neoplasm:



Diseases related to Jejunal Neoplasm

Symptoms & Phenotypes for Jejunal Neoplasm

GenomeRNAi Phenotypes related to Jejunal Neoplasm according to GeneCards Suite gene sharing:

27
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Reduced mammosphere formation GR00396-S 9.1 CD34 CDK4 CHGA KRT7 MDM2 MUC5AC

MGI Mouse Phenotypes related to Jejunal Neoplasm:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 renal/urinary system MP:0005367 9.1 CDK4 CHGA IFNG KIT KRT7 MDM2

Drugs & Therapeutics for Jejunal Neoplasm

Drugs for Jejunal Neoplasm (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):


# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Liver Extracts Phase 1
2 Cola Phase 1
3 Fluorodeoxyglucose F18
4 Antibodies
5 Immunoglobulins

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Study of TCM Syndrome of Hepatocellular Carcinoma and Colorectal Cancer Based on System Science Unknown status NCT03189992 Phase 1 Bushen-Jianpi Dedoction;cinobufotalin injection
2 Defining PET / CT Protocols With Optimized F18-FDG (Fluorodeoxyglucose) Dose, Focusing on Reduced Radiation Dose and Improved Image Quality Completed NCT02378337
3 Studying a Tumor Marker for Testicular Cancer, Skin Cancer, Small Intestine Cancer, and Pancreatic Cancer Terminated NCT00899132

Search NIH Clinical Center for Jejunal Neoplasm

Genetic Tests for Jejunal Neoplasm

Anatomical Context for Jejunal Neoplasm

MalaCards organs/tissues related to Jejunal Neoplasm:

42
Lung, Liver, Breast, Small Intestine, Skin, Prostate, Appendix

Publications for Jejunal Neoplasm

Articles related to Jejunal Neoplasm:

# Title Authors Year
1
Gastrointestinal stromal tumor of jejunum with angiodysplasia. ( 15185876 )
2004
2
Smooth muscle tumor of jejunum. A new mechanism of bleeding. ( 14462799 )
1962
3
Metastasizing "Carcinoid" Tumor of Jejunum. ( 19969926 )
1930

Variations for Jejunal Neoplasm

Expression for Jejunal Neoplasm

Search GEO for disease gene expression data for Jejunal Neoplasm.

Pathways for Jejunal Neoplasm

Pathways related to Jejunal Neoplasm according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.95 CALD1 KRT20 KRT7 MUC1
2 11.5 CD34 IFNG KIT
3 11.03 CD34 IFNG KIT
4 10.67 CD34 IFNG KIT

GO Terms for Jejunal Neoplasm

Cellular components related to Jejunal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 Golgi lumen GO:0005796 8.8 MUC1 MUC5AC MUC6

Biological processes related to Jejunal Neoplasm according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 stimulatory C-type lectin receptor signaling pathway GO:0002223 9.43 MUC1 MUC5AC MUC6
2 O-glycan processing GO:0016266 9.33 MUC1 MUC5AC MUC6
3 mast cell degranulation GO:0043303 9.32 CHGA KIT
4 mast cell chemotaxis GO:0002551 8.96 CHGA KIT
5 mast cell cytokine production GO:0032762 8.62 CHGA KIT

Sources for Jejunal Neoplasm

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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