MCID: JVN045
MIFTS: 17

Juvenile Ossifying Fibroma

Categories: Bone diseases, Cancer diseases, Oral diseases, Rare diseases

Aliases & Classifications for Juvenile Ossifying Fibroma

MalaCards integrated aliases for Juvenile Ossifying Fibroma:

Name: Juvenile Ossifying Fibroma 20 70

Classifications:



External Ids:

UMLS 70 C0457522

Summaries for Juvenile Ossifying Fibroma

GARD : 20 Juvenile ossifying fibroma (JOF) is rare, benign tumor of the craniofacial (skull and face) bones. It is considered a "fibro-osseous neoplasm " because it is characterized by an overgrowth of bone. Affected people generally experience a gradual or rapid, painless expansion of the affected bone or region. Other symptoms such as exophthalmos or nasal blockage can rarely be associated with the tumor depending on its exact location. In some cases, the condition can be particularly aggressive with rapid growth and significant facial disfigurement. Although the condition can affect people of all ages, it is most commonly diagnosed between the ages of 5 and 15. The exact underlying cause is currently unknown; however, most cases occur sporadically in people with no family history of the condition. JOF is usually treated with surgery. Because the recurrence rate of JOF ranges from 30% to 58%, continued follow-up is essential.

MalaCards based summary : Juvenile Ossifying Fibroma is related to ossifying fibroma and fibroma. An important gene associated with Juvenile Ossifying Fibroma is MDM2 (MDM2 Proto-Oncogene). Affiliated tissues include bone, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Juvenile Ossifying Fibroma

Diseases in the Ossifying Fibroma family:

Juvenile Ossifying Fibroma

Diseases related to Juvenile Ossifying Fibroma via text searches within MalaCards or GeneCards Suite gene sharing:

(showing 22, show less)
# Related Disease Score Top Affiliating Genes
1 ossifying fibroma 30.8 RASAL1 MDM2
2 fibroma 11.1
3 fibrous dysplasia 10.6
4 aneurysmal bone cysts 10.5
5 osteogenic sarcoma 10.4
6 exophthalmos 10.4
7 osteoblastoma 10.3
8 root resorption 10.2
9 burkitt lymphoma 10.1
10 cherubism 10.1
11 hypertelorism 10.1
12 yemenite deaf-blind hypopigmentation syndrome 10.1
13 meningioma, familial 10.1
14 osteofibrous dysplasia 10.1
15 dedifferentiated liposarcoma 10.1
16 intracranial meningioma 10.1
17 hyperparathyroidism 10.1
18 giant cell reparative granuloma 10.1
19 liposarcoma 10.1
20 secretory meningioma 10.1
21 lymphoplasmacyte-rich meningioma 10.1
22 back pain 10.1

Graphical network of the top 20 diseases related to Juvenile Ossifying Fibroma:



Diseases related to Juvenile Ossifying Fibroma

Symptoms & Phenotypes for Juvenile Ossifying Fibroma

GenomeRNAi Phenotypes related to Juvenile Ossifying Fibroma according to GeneCards Suite gene sharing:

26 (showing 16, show less)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-100 9.55 RASAL1
2 Increased shRNA abundance (Z-score > 2) GR00366-A-111 9.55 RASAL1
3 Increased shRNA abundance (Z-score > 2) GR00366-A-118 9.55 MDM2
4 Increased shRNA abundance (Z-score > 2) GR00366-A-136 9.55 MDM2
5 Increased shRNA abundance (Z-score > 2) GR00366-A-140 9.55 RASAL1
6 Increased shRNA abundance (Z-score > 2) GR00366-A-151 9.55 MDM2
7 Increased shRNA abundance (Z-score > 2) GR00366-A-153 9.55 MDM2
8 Increased shRNA abundance (Z-score > 2) GR00366-A-199 9.55 RASAL1
9 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.55 MDM2
10 Increased shRNA abundance (Z-score > 2) GR00366-A-43 9.55 MDM2 RASAL1
11 Increased shRNA abundance (Z-score > 2) GR00366-A-49 9.55 RASAL1
12 Increased shRNA abundance (Z-score > 2) GR00366-A-50 9.55 RASAL1
13 Increased shRNA abundance (Z-score > 2) GR00366-A-65 9.55 RASAL1
14 Increased shRNA abundance (Z-score > 2) GR00366-A-67 9.55 MDM2
15 Increased shRNA abundance (Z-score > 2) GR00366-A-77 9.55 RASAL1
16 Increased shRNA abundance (Z-score > 2) GR00366-A-83 9.55 RASAL1

Drugs & Therapeutics for Juvenile Ossifying Fibroma

Search Clinical Trials , NIH Clinical Center for Juvenile Ossifying Fibroma

Genetic Tests for Juvenile Ossifying Fibroma

Anatomical Context for Juvenile Ossifying Fibroma

MalaCards organs/tissues related to Juvenile Ossifying Fibroma:

40
Bone

Publications for Juvenile Ossifying Fibroma

Articles related to Juvenile Ossifying Fibroma:

(showing 151, show less)
# Title Authors PMID Year
1
Juvenile Psammomatoid Cemeto-ossifying Fibroma of Mandible: a Diagnostic dilemma. 61
33741572 2021
2
Entirely endoscopic resection of a complicated juvenile psammomatoid ossifying fibroma of the paranasal sinusitis: Case report and review of the literature. 61
33743250 2021
3
Cemento-ossifying fibroma and juvenile ossifying fibroma: Clarity in terminology. 61
33129707 2021
4
Rare case of juvenile ossifying fibroma of the lumbar spine causing vertebra plana. 61
33462042 2021
5
Primary Bone Tumors in North of Jordan. 61
33605114 2020
6
Endoscopic Optic Nerve Decompression for Optic Neuropathy in Sinonasal Fibro-Osseous Tumors. 61
32105872 2020
7
Intraoral Approach for Surgical Treatment of Psammomatoid Juvenile Ossifying Fibroma. 61
31934971 2020
8
Massive juvenile ossifying fibroma arising from the middle turbinate. 61
32295801 2020
9
Oral and Extraoral Intermediate Tumors: Are MMP-9 and Ki-67 Biomarkers Correlated to Their High Recurrence Rates? 61
30358613 2020
10
Juvenile ossifying fibroma of the jaws and paranasal sinuses: a systematic review of the cases reported in the literature. 61
31285096 2020
11
Simultaneous presentation of juvenile ossifying fibroma in the maxilla and mandible: a case report. 61
32480339 2020
12
Reconstruction and Mandibular Rehabilitation After Resection of Juvenile Aggressive Ossifying Fibroma Using Undifferentiated Mesenchymal Cells and Osseointegrated Implants: A Case Report. 61
31107685 2019
13
Craniofacial Approaches to Pediatric Orbital Tumors. 61
30865111 2019
14
Juvenile ossifying fibroma in a Nigerian boy: a rare case report. 61
31380504 2019
15
Two-stage surgical treatment for a giant sellar psammomatoid juvenile ossifying fibroma: case report. 61
30611151 2019
16
Management of an extensive equine juvenile ossifying fibroma by rostral mandibulectomy and reconstruction of the mandibular symphysis using String of Pearls plates with cortical and cancellous bone autografts. 61
30370537 2019
17
Case Report: rare hybrid lesion of a central giant cell granuloma within a juvenile ossifying fibroma. 61
31632653 2019
18
Juvenile Trabecular Ossifying Fibroma. 61
29027609 2018
19
Microvessel density and cell proliferation in juvenile ossifying fibroma: A comparative study with central ossifying fibroma. 61
30098514 2018
20
Psammomatoid variant of juvenile ossifying fibroma. 61
30004078 2018
21
Juvenile Ossifying Fibroma of Maxilla. 61
31719318 2018
22
Recurrent juvenile psammomatoid ossifying fibroma with secondary aneurysmal bone cyst of the maxilla: a case report and review of literature. 61
30090219 2018
23
Rare case of a recurrent juvenile ossifying fibroma of the lumbosacral spine. 61
29521580 2018
24
Juvenile Trabecular Ossifying Fibroma-a Case Report. 61
29887713 2018
25
Fibro-Osseous Lesions of the Skull Base in the Pediatric Population. 61
29404238 2018
26
Juvenile Ossifying Fibroma in the Mandible. 61
29963444 2018
27
Corrigendum to "Fibrous Dysplasia versus Juvenile Ossifying Fibroma: A Dilemma". 61
29992060 2018
28
Recurrent Psammomatoid Juvenile Ossifying Fibroma with Aneurysmal Bone Cyst: An Unusual Case Presentation. 61
29184270 2017
29
Cherubism. A case report. 61
27427211 2017
30
Costal graft as a support for bone regeneration after mandibular juvenile ossifying fibroma resection: An unusual case report. 61
28642188 2017
31
Psammomatoid Juvenile Ossifying Fibroma: Report of Three Cases with a Review of Literature. 61
29675079 2017
32
Trabecular Variant Juvenile Ossifying Fibroma of the Maxilla. 61
29152441 2017
33
Radiotherapy for juvenile ossifying fibroma of the maxillary sinus: Case report and literature review. 61
28467645 2017
34
Conglomeration of Trabecular and Psammomatoid variants of juvenile ossifying fibroma - a rare case report. 61
28588818 2017
35
Denosumab-treated giant cell tumor of bone. Its histologic spectrum and potential diagnostic pitfalls. 61
28235628 2017
36
Non-odontogenic tumors of the facial bones in children and adolescents: role of multiparametric imaging. 61
28289810 2017
37
Epithelioid osteoblastoma: A histopathological dilemma between juvenile ossifying fibroma and low-grade osteosarcoma. 61
28479709 2017
38
Psammomatoid Juvenile Ossifying Fibroma of Mandible in a 41-Year Male Patient. 61
28292370 2017
39
Juvenile Psammomatoid Ossifying Fibroma (JPOF) of Proximal Radius: A Rare Entity. 61
28932332 2017
40
Trabecular Variant: A Rare Entity of Juvenile Ossifying Fibroma of the Mandible. 61
28566876 2017
41
Juvenile Trabecular Ossifying Fibroma of the Maxilla: a Case Report. 61
28210024 2016
42
Le Fort I Disassembly for the Management of Juvenile Ossifying Fibroma Extending To the Skull Base. 61
27513775 2016
43
Polyostotic Juvenile Ossifying Fibroma: An Exceptionally Rare Case. 61
26068381 2016
44
A new subtype of high-grade mandibular osteosarcoma with RASAL1/MDM2 amplification. 61
26997440 2016
45
Juvenile ossifying fibroma of the jaw: a retrospective study of 15 cases. 61
26740351 2016
46
Reconstruction of Extended Orbitomaxillectomy and Hemimandibulectomy Defects With Fibula Flaps and Patient-Specific Implants. 61
26900747 2016
47
Psammomatoid juvenile ossifying fibroma of mandible in a 6-year-old child. 61
27134454 2016
48
Fibrous Dysplasia versus Juvenile Ossifying Fibroma: A Dilemma. 61
28101383 2016
49
Psammomatoid variant of juvenile ossifying fibroma involving mandible: A rare case report. 61
26681872 2015
50
Management and Treatment Outcomes of Maxillofacial Fibro-osseous Lesions: A Retrospective Study. 61
26225069 2015
51
Psammomatoid Juvenile Ossifying Fibroma Involving Upper Jaw: A Rare Case Report. 61
26393222 2015
52
Is Computed Tomography an Adequate Imaging Modality for the Evaluation of Juvenile Ossifying Fibroma? A Comparison of 2 Imaging Modalities (Computed Tomography and Magnetic Resonance Imaging). 61
25911216 2015
53
Juvenile ossifying fibroma of the maxilla: a case report. 61
25838672 2015
54
Intranasal endoscopic prelacrimal recess approach to sinonasal juvenile ossifying fibroma. 61
25635449 2015
55
Treatment Challenges with Benign Bone Tumors of the Orbit. 61
27171013 2015
56
Juvenile ossifying fibroma diagnosed on fine needle aspiration cytology: a diagnostic challenge. 61
24591292 2015
57
Chromosome 12 long arm rearrangement covering MDM2 and RASAL1 is associated with aggressive craniofacial juvenile ossifying fibroma and extracranial psammomatoid fibro-osseous lesions. 61
24925056 2015
58
Tumors of the pediatric maxillofacial skeleton: a 20-year clinical study. 61
25393657 2015
59
Aneurysmal Bone Cyst of the Jaws: Clinicopathological Study. 61
26225011 2014
60
Psammomatoid and trabecular juvenile ossifying fibroma: two distinct radiologic entities. 61
25457891 2014
61
Juvenile ossifying fibroma with aneurysamal bone cyst: a case report. 61
25478458 2014
62
Aggressive multilocular osteoblastoma in the mandible: a rare and difficult case to diagnose. 61
25517784 2014
63
Juvenile aggressive ossifying fibroma of the maxilla: a case report. 61
25395805 2014
64
Minimally invasive endoscopic removal of a massive trabecular juvenile ossifying fibroma of the paranasal sinuses. 61
25129190 2014
65
A Clinicopathologic Analysis of 207 Cases of Benign Fibro-Osseous Lesions of the Jaws. 61
24326826 2014
66
Juvenile ossifying fibroma of the middle turbinate. 61
25075725 2014
67
Juvenile trabecular ossifying fibroma. 61
24872635 2014
68
Psammomatoid juvenile ossifying fibroma: case study and a review. 61
23435579 2014
69
Correction: Psammomatoid Juvenile Ossifying Fibroma of the Maxilla: Radical Surgery with Maxillary Resection in a 7-year-old Girl. 61
24449425 2013
70
Psammomatoid juvenile ossifying fibroma of the maxilla: radical surgery with maxillary resection in a 7-year-old girl. 61
24166092 2013
71
Juvenile ossifying fibroma of mandible: a case report. 61
24431886 2013
72
Case report: Trabecular juvenile ossifying fibroma presenting as a sellar mass. 61
22777925 2013
73
Juvenile psammomatoid ossifying fibroma: An unusual case report. 61
24403813 2013
74
A massive sinonasal psammomatoid variant of juvenile ossifying fibroma: Report of a rare entity. 61
24250099 2013
75
Juvenile ossifying fibroma of paranasal sinuses-do we need to be radical in surgery? 61
23714983 2013
76
Juvenile ossifying fibroma of the maxilla: a rare aggressive case in a young patient. 61
23771389 2013
77
Rare pediatric presentation of aneurysmal bone cyst with trabecular juvenile ossifying fibroma and ossifying fibroma. 61
23305772 2013
78
Clinicopathologic and radiologic correlation of ossifying fibroma and juvenile ossifying fibroma--an institutional study of 22 cases. 61
22841475 2013
79
Carnoy's in Aggressive Lesions: Our Experience. 61
24431812 2013
80
Recurrent ossifying fibroma of the maxillary sinus in an adult patient. 61
23858945 2013
81
Psammomatoid type juvenile ossifying fibroma of mandible. 61
23662272 2013
82
Juvenile ossifying fibroma: Psammamatoid variant. 61
23293493 2012
83
Psammomatoid juvenile ossifying fibroma: an analysis of 2 cases affecting the mandible with review of the literature. 61
22668716 2012
84
Trabecular variant of juvenile aggressive ossifying fibroma of anterior mandible. 61
22803002 2012
85
Trabeculae type of juvenile aggressive ossifying fibroma of the maxilla: Report of two cases. 61
22629066 2012
86
Mandibular mass in pediatric patient: a diagnostic dilemma. 61
22918108 2012
87
Early experience of radio frequency coblation in the management of intranasal and sinus tumors. 61
22252897 2012
88
[Juvenile ossifying fibroma: a misgiving tumor of the jaws]. 61
22325316 2012
89
Juvenile psammomatoid ossifying fibroma: a review. 61
21840246 2011
90
Juvenile ossifying fibroma of the maxilla. 61
21596643 2011
91
Surgical management of two complex cases of large juvenile orbital ossifying fibroma. 61
21741889 2011
92
General practitioner's radiology case 96. Juvenile ossifying fibroma. 61
23477273 2011
93
Intraoral sublabial approach for anterior skull base juvenile ossifying fibroma. 61
21959488 2011
94
Psammomatoid juvenile ossifying fibroma of the jaws. 61
22144839 2011
95
"Hybrid" lesion of the maxilla. 61
22144833 2011
96
Trabecular juvenile ossifying fibroma with aneurysmal bone cyst: a rare presentation. 61
22104705 2011
97
Paranasal ossifying fibroma: endoscopic resection or wait and scan? 61
21298389 2011
98
Juvenile Psammomatoid Ossifying Fibroma (JPOF) of Maxilla-a Rare Entity. 61
22654369 2011
99
Oral and maxillofacial pathology case of the month: Trabecular juvenile ossifying fibroma. 61
21834371 2011
100
Juvenile ossifying fibroma of the maxilla. 61
22696727 2011
101
Rapidly maturing juvenile ossifying fibroma: a case report. 61
21346088 2011
102
Trabecular and psammomatoid juvenile ossifying fibroma of the skull base mimicking psammomatoid meningioma. 61
20953744 2011
103
Fibro-osseous Lesions of the Jaw: A Report of Two Cases. 61
21977383 2011
104
Fibro-osseous lesions vs. central giant cell granuloma: A hybrid lesion. 61
23483611 2011
105
Juvenile central ossifying fibroma of the mandible: a case report. 61
20920702 2010
106
An estimate of the rate of growth of a juvenile aggressive ossifying fibroma in a 15 year old child. 61
20587961 2010
107
Juvenile trabecular ossifying fibroma of the mandible. 61
23139578 2010
108
Management of juvenile ossifying fibroma in the maxilla and mandible. 61
23139579 2010
109
Juvenile ossifying fibroma of maxilla. 61
23139580 2010
110
Juvenile ossifying fibroma of the mandible: a case report. 61
24421970 2010
111
Juvenile ossifying fibroma of the maxilla. 61
20455356 2010
112
Endoscopic resection of an aggressive juvenile ossifying fibroma. 61
21225821 2010
113
Best cases from the AFIP: juvenile ossifying fibroma of the calvaria. 61
19605666 2009
114
Psammomatoid and trabecular variants of juvenile ossifying fibroma-two case reports. 61
19881065 2009
115
Juvenile ossifying fibroma of the jaw. 61
18206279 2008
116
From the Archives of the AFIP. Pediatric orbit tumors and tumorlike lesions: osseous lesions of the orbit. 61
18635637 2008
117
Juvenile ossifying fibroma of maxilla: report of a case. 61
19093652 2008
118
Juvenile ossifying fibroma of the maxilla. 61
17018252 2007
119
What is your diagnosis? Chronic juvenile ossifying fibroma. 61
17144815 2006
120
Spontaneous regeneration after juvenile ossifying fibroma resection: a case report. 61
17052621 2006
121
HRPT2 gene alterations in ossifying fibroma of the jaws. 61
16458039 2006
122
Proptosis in a young child. 61
16816521 2006
123
Oromaxillofacial osseous abnormality in Sturge-Weber syndrome: case report and review of the literature. 61
16484391 2006
124
Juvenile ossifying fibroma: a case study. 61
15580124 2004
125
Juvenile ossifying fibroma of the mandible. 61
12677589 2003
126
Aggressive psammomatoid ossifying fibroma of the inferior turbinate and lateral nasal wall. 61
12642959 2003
127
[Juvenile ossifying fibroma. Case report with diagnostic and therapeutic considerations]. 61
12556986 2003
128
Juvenile ossifying fibroma: CT and MR findings. 61
12522617 2002
129
Sublabial approach to sinonasal juvenile ossifying fibroma. 61
12090953 2002
130
Psammomatoid and trabecular juvenile ossifying fibroma of the craniofacial skeleton: two distinct clinicopathologic entities. 61
11925539 2002
131
Juvenile ossifying fibroma. An analysis of eight cases and a comparison with other fibro-osseous lesions. 61
10678711 2000
132
Juvenile ossifying fibroma of the midface. 61
10726516 1999
133
Cysts and cystic lesions of the mandible: clinical and radiologic-histopathologic review. 61
10489168 1999
134
Juvenile ossifying fibroma of the mandible. An 8 year radiological follow-up. 61
10895636 1998
135
Juvenile ossifying fibroma of the orbit. 61
8869972 1996
136
Maxillofacial fibro-osseous lesions: classification and differential diagnosis. 61
8734416 1996
137
Juvenile ossifying fibroma of the maxilla in a 6-year-old male: case report. 61
8524687 1995
138
Juvenile ossifying fibroma. An analysis of 33 cases with emphasis on histopathological aspects. 61
7823298 1994
139
[Juvenile ossifying fibroma or desmo-osteoblastoma: apropos of a case]. 61
8036443 1994
140
Pathologic quiz case 2. Psammomatoid (juvenile) ossifying fibroma (POF) of the ethmoid sinus. 61
1389066 1992
141
Differential diagnosis of fibro-osseous jaw lesions. A histological investigation on 30 cases. 61
2387909 1990
142
Juvenile ossifying fibroma. Report of four cases. 61
2345185 1990
143
[Juvenile ossifying fibroma of the facial skull. Computerized tomography and nuclear magnetic resonance tomography]. 61
3685328 1987
144
[3-dimensional reconstruction of a juvenile ossifying fibroma. A spatial-histological study of pathogenesis--a case report]. 61
3482018 1986
145
Massive juvenile ossifying fibroma of maxillary sinus with orbital involvement. 61
3994958 1985
146
Psammomatoid (juvenile) ossifying fibroma of the orbit. 61
3974992 1985
147
Clinical, computed tomographic, and histopathologic characteristics of juvenile ossifying fibroma with orbital involvement. 61
6638132 1983
148
Juvenile ossifying fibroma: an ultrastructural study. 61
103613 1978
149
Clinicopathological conference. Case 17, part 2. Juvenile ossifying fibroma. 61
823316 1976
150
[Juvenile ossifying fibroma (apropos of 2 cases)]. 61
1065245 1976
151
[Aggressive juvenile ossifying fibroma of the left mandible]. 61
4218680 1974

Variations for Juvenile Ossifying Fibroma

Expression for Juvenile Ossifying Fibroma

Search GEO for disease gene expression data for Juvenile Ossifying Fibroma.

Pathways for Juvenile Ossifying Fibroma

GO Terms for Juvenile Ossifying Fibroma

Sources for Juvenile Ossifying Fibroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
Content
Loading form....