JTA
MCID: JVN019
MIFTS: 27

Juvenile Temporal Arteritis (JTA)

Categories: Bone diseases, Cardiovascular diseases, Muscle diseases, Nephrological diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Juvenile Temporal Arteritis

MalaCards integrated aliases for Juvenile Temporal Arteritis:

Name: Juvenile Temporal Arteritis 52 58 71
Juvenile Giant Cell Arteritis 52 71
Non-Giant Cell Granulomatous Temporal Arteritis with Eosinophilia 58
Juvenile Polymyalgia Rheumatica 52
Juvenile Cranial Arteritis 52
Jgca 52
Jpmr 52
Jta 58

Characteristics:

Orphanet epidemiological data:

58
juvenile temporal arteritis
Prevalence: <1/1000000 (Worldwide); Age of onset: Childhood;

Classifications:

Orphanet: 58  
Rare circulatory system diseases
Rare systemic and rhumatological diseases


External Ids:

ICD10 via Orphanet 33 L95.8
UMLS via Orphanet 72 C0751547
Orphanet 58 ORPHA26137
SNOMED-CT via HPO 68 25064002 61582004 95319004 more
UMLS 71 C0751547 C2931873

Summaries for Juvenile Temporal Arteritis

NIH Rare Diseases : 52 Juvenile temporal arteritis is a rare form of vasculitis , a group of conditions that cause inflammation of the blood vessels. Unlike the classic form of temporal arteritis , this condition is generally diagnosed in late childhood or early adulthood and only affects the temporal arteries (located at the lower sides of the skull, directly underneath the temple). Affected people often have no signs or symptoms aside from a painless nodule or lump in the temporal region. The exact underlying cause of the condition is unknown. It generally occurs sporadically in people with no family history of the condition. Juvenile temporal arteritis is often treated with surgical excision and rarely recurs .

MalaCards based summary : Juvenile Temporal Arteritis, also known as juvenile giant cell arteritis, is related to gastric cancer and temporal arteritis. The drugs Capecitabine and Epinephrine have been mentioned in the context of this disorder. Affiliated tissues include skin and bone, and related phenotypes are headache and skin nodule

Related Diseases for Juvenile Temporal Arteritis

Diseases in the Temporal Arteritis family:

Juvenile Temporal Arteritis

Diseases related to Juvenile Temporal Arteritis via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 19)
# Related Disease Score Top Affiliating Genes
1 gastric cancer 10.6
2 temporal arteritis 10.6
3 hypereosinophilic syndrome 10.4
4 ischemia 10.3
5 microinvasive gastric cancer 10.3
6 kimura disease 10.2
7 vasculitis 10.1
8 lipomatosis, multiple 9.9
9 scleroderma, familial progressive 9.9
10 thrombophilia due to activated protein c resistance 9.9
11 buerger disease 9.9
12 benign teratoma 9.9
13 pleomorphic lipoma 9.9
14 cystic teratoma 9.9
15 cellulitis 9.9
16 mature teratoma 9.9
17 polyarteritis nodosa 9.9
18 wells syndrome 9.9
19 raynaud phenomenon 9.9

Graphical network of the top 20 diseases related to Juvenile Temporal Arteritis:



Diseases related to Juvenile Temporal Arteritis

Symptoms & Phenotypes for Juvenile Temporal Arteritis

Human phenotypes related to Juvenile Temporal Arteritis:

58 31 (show all 8)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 headache 58 31 frequent (33%) Frequent (79-30%) HP:0002315
2 skin nodule 58 31 frequent (33%) Frequent (79-30%) HP:0200036
3 conjunctivitis 58 31 occasional (7.5%) Occasional (29-5%) HP:0000509
4 eosinophilia 58 31 occasional (7.5%) Occasional (29-5%) HP:0001880
5 allergic rhinitis 58 31 occasional (7.5%) Occasional (29-5%) HP:0003193
6 cerebral ischemia 58 Excluded (0%)
7 leukocytosis 58 Frequent (79-30%)
8 vasculitis 58 Excluded (0%)

Drugs & Therapeutics for Juvenile Temporal Arteritis

Drugs for Juvenile Temporal Arteritis (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Capecitabine Approved, Investigational Phase 3 154361-50-9 60953
2
Epinephrine Approved, Vet_approved Phase 3 51-43-4 5816
3
Racepinephrine Approved Phase 3 329-65-7 838
4 Antimetabolites Phase 3
5 Neurotransmitter Agents Phase 3
6 Sympathomimetics Phase 3
7 Adrenergic Agonists Phase 3
8 Epinephryl borate Phase 3
9 Respiratory System Agents Phase 3
10 Anti-Asthmatic Agents Phase 3
11 Pharmaceutical Solutions Phase 3
12 Vasoconstrictor Agents Phase 3
13 Adrenergic beta-Agonists Phase 3
14 Autonomic Agents Phase 3
15 Bronchodilator Agents Phase 3
16 Mydriatics Phase 3
17 Adrenergic Agents Phase 3
18
Cisplatin Approved Phase 2 15663-27-1 84093 441203 2767
19
Fluorouracil Approved Phase 2 51-21-8 3385
20
Docetaxel Approved, Investigational Phase 2 114977-28-5 148124
21 Immunologic Factors Phase 2
22
s 1 (combination) Phase 2
23 Antimitotic Agents Phase 2
24 Immunosuppressive Agents Phase 2
25
Midazolam Approved, Illicit 59467-70-8 4192

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Capecitabine or Observation for Patients With pT1N+M0 or pT2-3N0M0 Gastric Adenocarcinoma Undergoing R0 Resection (CAPOGA): A Large Multicenter Phase III Randomized Controlled Trial Recruiting NCT03817268 Phase 3 Capecitabine monotherapy
2 Multicenter Randomized Controlled Trial of Gastric Endoscopic Submucosal Dissection With or Without Epineprhine Added Solution Recruiting NCT04032119 Phase 3 Epinephrine
3 Laparoscopic Gastrectomy for Advanced Gastric Cancer Completed NCT01441336 Phase 2
4 A Randomized Phase II Trial of Neoadjuvant Combination Chemotherapy of DCS (Cisplatin + Docetaxel + S-1) and DCF (Docetaxel + Cisplatin + 5-FU) in Patients With Locally Advanced Gastric Adenocarcinoma Completed NCT01286766 Phase 2 DCS (docetaxel with cisplatin with TS-1);DCF (docetaxel with cisplatin with 5-FU)
5 Prospective Randomized Trial of Laparoscopic Versus Open Gastrectomy for Advanced Gastric Cancer Unknown status NCT01043835
6 The Origin of Infrapyloric Artery: an Observational Trial Completed NCT03071237
7 The Relationship Between the Length of the Proximal Resection Margin and Long-term Survival for Adenocarcinomas of the Esophagogastric Junction (Siewert-II/Siewert-III)- Randomized Controlled Trial Recruiting NCT02313688
8 Fluorescence Image-Guided Lymphadenectomy Using Indocyanine Green and Near Infrared Technology in Robotic Gastrectomy Recruiting NCT03931044

Search NIH Clinical Center for Juvenile Temporal Arteritis

Genetic Tests for Juvenile Temporal Arteritis

Anatomical Context for Juvenile Temporal Arteritis

MalaCards organs/tissues related to Juvenile Temporal Arteritis:

40
Skin, Bone

Publications for Juvenile Temporal Arteritis

Articles related to Juvenile Temporal Arteritis:

(show all 26)
# Title Authors PMID Year
1
Angiolymphoid Hyperplasia with Eosinophilia with Clinical Presentation Concerning for Juvenile Temporal Arteritis. 61
32002401 2020
2
Concurrent bilateral juvenile temporal arteritis and hypereosinophilic syndrome: a case report and review of the literature. 61
31384578 2019
3
Juvenile temporal arteritis: A clinicopathological multicentric experience. 61
30844551 2019
4
Image Gallery: Bilateral juvenile temporal arteritis. 61
30318798 2018
5
Juvenile temporal arteritis with eosinophilia associated with systemic sclerosis. 61
27401371 2017
6
Methotrexate in refractory bilateral juvenile temporal arteritis: Report of a case. 61
24252028 2016
7
Temporal arteritis in a young patient. 61
24143876 2014
8
Temporal arteritis in the young. 61
23142255 2013
9
Juvenile temporal arteritis. 61
23294490 2013
10
Juvenile temporal arteritis with perifollicular lymphoid proliferation resembling Kimura disease. Report of a case. 61
21182505 2011
11
Juvenile temporal arteritis. 61
19748701 2010
12
Vasculitis of the temporal arteries in the young. 61
18538831 2009
13
Hypereosinophilic syndrome with various skin lesions and juvenile temporal arteritis. 61
19077087 2009
14
Juvenile temporal arteritis: a case report. 61
16373237 2005
15
Juvenile temporal arteritis associated with Kimura's disease. 61
16011665 2005
16
Juvenile temporal arteritis: a case report and review of the literature. 61
15144142 2004
17
Juvenile temporal arteritis and activated protein C resistance. 61
14722218 2004
18
[Juvenile temporal arteritis: a benign disease]. 61
12650899 2003
19
Juvenile temporal arteritis is a manifestation of Kimura disease. 61
11803281 2002
20
Temporal arteritis in a patient with eosinophilia. 61
19078449 2000
21
Juvenile temporal arteritis with eosinophilia: a distinct clinicopathological entity. 61
8832949 1996
22
Bilateral juvenile temporal arteritis. 61
7791181 1995
23
Juvenile temporal arteritis revisited. 61
8170196 1994
24
[Temporal arteritis in young subjects. A trial of nosological classification apropos of 6 cases]. 61
1482033 1992
25
Does juvenile temporal arteritis exist. 61
1036510 1976
26
Juvenile temporal arteritis. Biopsy study of four cases. 61
240951 1975

Variations for Juvenile Temporal Arteritis

Expression for Juvenile Temporal Arteritis

Search GEO for disease gene expression data for Juvenile Temporal Arteritis.

Pathways for Juvenile Temporal Arteritis

GO Terms for Juvenile Temporal Arteritis

Sources for Juvenile Temporal Arteritis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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