MCID: JXT001
MIFTS: 27

Juxtacortical Chondroma

Categories: Cancer diseases

Aliases & Classifications for Juxtacortical Chondroma

MalaCards integrated aliases for Juxtacortical Chondroma:

Name: Juxtacortical Chondroma 12 15 71
Periosteal Chondroma 12

Classifications:



External Ids:

Disease Ontology 12 DOID:2601
NCIt 49 C4302
SNOMED-CT 67 9266000
UMLS 71 C0334548

Summaries for Juxtacortical Chondroma

MalaCards based summary : Juxtacortical Chondroma, also known as periosteal chondroma, is related to chondroma and enchondroma, and has symptoms including pain An important gene associated with Juxtacortical Chondroma is KDM4C (Lysine Demethylase 4C), and among its related pathways/superpathways are Carbon metabolism and Citrate cycle (TCA cycle). Affiliated tissues include bone, spinal cord and cortex.

Related Diseases for Juxtacortical Chondroma

Diseases related to Juxtacortical Chondroma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 70)
# Related Disease Score Top Affiliating Genes
1 chondroma 31.7 IDH1 EXT2
2 enchondroma 31.1 IDH2 IDH1
3 osteochondroma 30.6 EXT2 EXT1
4 periosteal chondrosarcoma 30.5 IDH2 IDH1 EXT1
5 hereditary multiple osteochondromas 30.4 EXT2 EXT1
6 hereditary multiple exostoses 30.0 EXT2 EXT1
7 chondrosarcoma 29.8 IDH2 IDH1 EXT2 EXT1
8 breast intraductal papillomatosis 10.3 IDH2 IDH1
9 intraductal papilloma 10.3 IDH2 IDH1
10 breast duct papilloma 10.3 IDH2 IDH1
11 breast papillomatosis 10.3 IDH2 IDH1
12 adult brain stem glioma 10.3 IDH2 IDH1
13 cytogenetically normal acute myeloid leukemia 10.3 IDH2 IDH1
14 intracranial chondrosarcoma 10.3 IDH2 IDH1
15 breast hemangioma 10.3 IDH2 IDH1
16 adult oligodendroglioma 10.3 IDH2 IDH1
17 childhood oligodendroglioma 10.3 IDH2 IDH1
18 interval angle-closure glaucoma 10.3 IDH2 IDH1
19 gemistocytic astrocytoma 10.3 IDH2 IDH1
20 adult astrocytic tumour 10.3 IDH2 IDH1
21 intraductal breast benign neoplasm 10.2 IDH2 IDH1
22 combined d-2- and l-2-hydroxyglutaric aciduria 10.2 KDM4C IDH2
23 breast benign neoplasm 10.2 IDH2 IDH1
24 mixed oligodendroglioma-astrocytoma 10.2 IDH2 IDH1
25 mixed glioma 10.2 IDH2 IDH1
26 dysembryoplastic neuroepithelial tumor 10.2 KDM4C IDH1
27 spindle cell hemangioma 10.2 IDH2 IDH1
28 brain stem cancer 10.2 KDM4C IDH1
29 gliomatosis cerebri 10.2 KDM4C IDH1
30 dysplasia epiphysealis hemimelica 10.2 EXT2 EXT1
31 ankylosing spondylitis 3 10.1 EXT2 EXT1
32 thoracic benign neoplasm 10.1 IDH2 IDH1
33 l-2-hydroxyglutaric aciduria 10.1 KDM4C IDH2 IDH1
34 fibrillary astrocytoma 10.1 KDM4C IDH2 IDH1
35 carpal tunnel syndrome 10.1
36 osteogenic sarcoma 10.1
37 aneurysmal bone cysts 10.1
38 rickets 10.1
39 secondary hyperparathyroidism 10.1
40 hyperparathyroidism 10.1
41 hyperostosis 10.1
42 osgood-schlatter's disease 10.1
43 myeloid leukemia 10.1
44 bizarre parosteal osteochondromatous proliferation 10.1
45 occipital neuralgia 10.1
46 paresthesia 10.1
47 rare tumor 10.1
48 brain stem glioma 10.1 KDM4C IDH2 IDH1
49 brain glioma 10.1 KDM4C IDH2 IDH1
50 bile duct adenocarcinoma 10.1 KDM4C IDH2 IDH1

Graphical network of the top 20 diseases related to Juxtacortical Chondroma:



Diseases related to Juxtacortical Chondroma

Symptoms & Phenotypes for Juxtacortical Chondroma

UMLS symptoms related to Juxtacortical Chondroma:


pain

Drugs & Therapeutics for Juxtacortical Chondroma

Search Clinical Trials , NIH Clinical Center for Juxtacortical Chondroma

Genetic Tests for Juxtacortical Chondroma

Anatomical Context for Juxtacortical Chondroma

MalaCards organs/tissues related to Juxtacortical Chondroma:

40
Bone, Spinal Cord, Cortex

Publications for Juxtacortical Chondroma

Articles related to Juxtacortical Chondroma:

(show top 50) (show all 127)
# Title Authors PMID Year
1
Calcified or ossified benign soft tissue lesions that may simulate malignancy. 61
31297550 2019
2
Benign bone tumours of tibial tuberosity clinically mimicking Osgood-Schlatter disease: a case series. 61
31511951 2019
3
Resection of Cervical Juxtacortical Chondroma and Circumferential Spinal Stabilization for Kyphotic Deformity. 61
31259132 2019
4
Bullough's Lesion: An Unexpected Diagnosis After the Resection of a Slowly Growing Osseous-Like Retroauricular Bump-Case Report and Review of the Literature. 61
30448575 2019
5
[Atypical periosteal chondroma of the hip: a case report]. 61
30332884 2018
6
Cervical Periosteal Chondroma Causing Spinal Cord or Nerve Compression: 2 Case Reports and Literature Review. 61
29550598 2018
7
Periosteal chondroma of the cuboid with secondary aneurysmal bone cyst in a setting of secondary hyperparathyroidism. 61
29413778 2018
8
Novel case of Trevor's disease: Adult onset and later recurrence. 61
28144583 2017
9
Periosteal chondroma with spinal cord compression in the thoracic spinal canal: a case report. 61
27179652 2016
10
Enchondroma Protuberans of the Ulna in a Pediatric Patient: A Case Report. 61
29252631 2016
11
Congenital bizarre parosteal osteochondromatous proliferation in unusual location and age: a case report. 61
26854060 2016
12
Recurrent 12q13-15 chromosomal aberrations, high frequency of isocitrate dehydrogenase 1 mutations, and absence of high mobility group AT-hook 2 expression in periosteal chondromas. 61
26170993 2015
13
Periosteal chondroma of the distal tibia: Computed tomography and magnetic resonance imaging characteristics and correlation with histological findings. 61
26137286 2015
14
Periosteal chondroma of the femur: A case report and review of the literature. 61
25789014 2015
15
Extensive Periosteal Chondroma in the Middle Phalanx with Pathological Fracture Reconstructed with Strut Bone Grafting. 61
26051780 2015
16
A case of benign periosteal chondroma seeding into humeral medullary bone via percutaneous needle biopsy tract. 61
30363208 2015
17
A giant periosteal chondroma of the distal femur successfully reconstructed with synthetic bone grafts and a bioresorbable plate: a case report. 61
25416085 2014
18
Focal periosteal chondroma of the hand: a review of 24 cases. 61
25172018 2014
19
Thymoma with osseous metaplasia in an adolescent. 61
24442387 2014
20
Usefulness of PET/CT for diagnosis of periosteal chondrosarcoma of the femur: A case report. 61
24932240 2014
21
Imaging features of juxtacortical chondroma in children. 61
23955368 2014
22
Imaging features of periosteal chondroma manifesting as a subcutaneous mass in the index finger. 61
24778891 2014
23
Compression of the digital nerves by a giant periosteal chondroma. 61
23245470 2013
24
Primary juxtacortical myoepithelioma/mixed tumor of the bone: a report of 3 cases with clinicopathologic, immunohistochemical, ultrastructural, and molecular characterization. 61
23079205 2013
25
Loss of β-catenin induces multifocal periosteal chondroma-like masses in mice. 61
23274133 2013
26
Periosteal chondroma of the proximaltibia mimicking Osgood-Schlatter's disease. 61
23610879 2013
27
Giant periosteal chondroma of the rib associated with mediastinum deviation. 61
22916761 2012
28
The imaging of cartilaginous bone tumours. I. Benign lesions. 61
22707094 2012
29
Periosteal chondroma of the ischium; an unusual location. 61
22627638 2012
30
Periosteal chondroma that presented as a subcutaneous mass in the ring finger. 61
21504284 2011
31
A report of a rare phalangeal periosteal chondroma of the foot. 61
21172646 2011
32
A pathologic fracture of an intracortical chondroma masking as an osteoid osteoma. 61
21053879 2010
33
Cervical spine chondroma arising from C5 right hemilamina: a rare cause of spinal cord compression. Case report and review of the literature. 61
21423079 2010
34
Periosteal chondroma of the clavicle: case report and review of the literature. 61
19185557 2009
35
Periosteal osteoblastoma of the distal femur. 61
19492573 2009
36
Periosteal chondroma of the pediatric cervical spine. 61
19278317 2009
37
Pediatric rib lesions: a 13-year experience. 61
18926207 2008
38
Periosteal chondroma of the sacrum. 61
18841229 2008
39
Juxtacortical chondroma of the sacrum. 61
18843465 2008
40
Periosteal chondroma at birth. 61
18369616 2008
41
Solitary periosteal chondroma presenting as a snapping finger: an unusual location. 61
19054834 2008
42
A periosteal chondroma in the lumbar spinal canal. Case report. 61
17933323 2007
43
[Chondromas (enchondroma, periosteal chondroma, enchondromatosis)]. 61
18074822 2007
44
First occurrence of periosteal chondroma (juxtacortical chondroma) in Uromastyxmaliensis (Reptilia: Sauria: Agamidae). 61
17867460 2007
45
Bizarre parosteal osteochondromatous proliferation and periosteal chondroma: a comparative report and review of the literature. 61
17606073 2007
46
Subperiosteal chondromyxoid fibroma: a report of two cases. 61
17907440 2007
47
Periosteal chondroma of the proximal humerus: a case report and review of the literature. 61
17205883 2006
48
Periosteal chondroma of the rib possibly associated with hemothorax: a case report. 61
17011256 2006
49
Soft tissue osteochondroma: case report and immunohistochemistry for parathyroid hormone-related protein. 61
16844564 2006
50
Concurrent periosteal chondroma and enchondroma of the fibula mimicking chondrosarcoma. 61
16421751 2006

Variations for Juxtacortical Chondroma

Expression for Juxtacortical Chondroma

Search GEO for disease gene expression data for Juxtacortical Chondroma.

Pathways for Juxtacortical Chondroma

GO Terms for Juxtacortical Chondroma

Biological processes related to Juxtacortical Chondroma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.78 KDM4C IDH3G IDH2 IDH1
2 glycosaminoglycan biosynthetic process GO:0006024 9.46 EXT2 EXT1
3 heparan sulfate proteoglycan biosynthetic process GO:0015012 9.43 EXT2 EXT1
4 2-oxoglutarate metabolic process GO:0006103 9.4 IDH2 IDH1
5 NADP metabolic process GO:0006739 9.37 IDH2 IDH1
6 tricarboxylic acid cycle GO:0006099 9.33 IDH3G IDH2 IDH1
7 heparan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process GO:0015014 9.32 EXT2 EXT1
8 cellular polysaccharide biosynthetic process GO:0033692 9.26 EXT2 EXT1
9 glyoxylate cycle GO:0006097 8.96 IDH2 IDH1
10 isocitrate metabolic process GO:0006102 8.8 IDH3G IDH2 IDH1

Molecular functions related to Juxtacortical Chondroma according to GeneCards Suite gene sharing:

(show all 11)
# Name GO ID Score Top Affiliating Genes
1 metal ion binding GO:0046872 10.03 ZFC3H1 MIB1 KDM4C IDH3G IDH2 IDH1
2 magnesium ion binding GO:0000287 9.65 IDH3G IDH2 IDH1
3 oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor GO:0016616 9.5 IDH3G IDH2 IDH1
4 acetylglucosaminyltransferase activity GO:0008375 9.49 EXT2 EXT1
5 glucuronosyltransferase activity GO:0015020 9.46 EXT2 EXT1
6 NAD binding GO:0051287 9.43 IDH3G IDH2 IDH1
7 heparan sulfate N-acetylglucosaminyltransferase activity GO:0042328 9.4 EXT2 EXT1
8 glucuronosyl-N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase activity GO:0050508 9.37 EXT2 EXT1
9 N-acetylglucosaminyl-proteoglycan 4-beta-glucuronosyltransferase activity GO:0050509 9.16 EXT2 EXT1
10 isocitrate dehydrogenase (NADP+) activity GO:0004450 8.96 IDH2 IDH1
11 isocitrate dehydrogenase activity GO:0004448 8.62 IDH2 IDH1

Sources for Juxtacortical Chondroma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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