|
KTCN7
MCID: KRT053
MIFTS: 18
|
Keratoconus 7 (KTCN7)
Categories:
Eye diseases, Genetic diseases, Neuronal diseases, Rare diseases
|
|
|
|
MalaCards integrated aliases for Keratoconus 7:
Characteristics:HPO:31Classifications:
MalaCards categories:
Global: Genetic diseases Rare diseases Anatomical: Eye diseases Neuronal diseases |
|
OMIM® :
57
Keratoconus (KTCN) is a noninflammatory thinning and consequent bulging of the cornea that results in distortion of the corneal surface, altered refractive powers of the eye (both axial and refractive), and reduced visual acuity. In more advanced cases, corneal scarring further reduces visual acuity. Symptoms are highly variable and depend on the stage of the progression of the disorder. The trait has an incidence of approximately 1 in 2,000 individuals and is the most common indication for corneal transplantation in the United States (summary by Gajecka et al., 2009).
For a discussion of genetic heterogeneity of keratoconus, see KTCN1 (148300). (614629) (Updated 05-Mar-2021)
MalaCards based summary : Keratoconus 7, also known as ktcn7, is related to astigmatism and keratoconus. An important gene associated with Keratoconus 7 is KTCN7 (Keratoconus 7). Affiliated tissues include eye, and related phenotype is keratoconus. |
Diseases in the Keratoconus family:
Diseases related to Keratoconus 7 via text searches within MalaCards or GeneCards Suite gene sharing:
|
Human phenotypes related to Keratoconus 7:31
Symptoms via clinical synopsis from OMIM®:57 (Updated 05-Mar-2021)Clinical features from OMIM®:614629 (Updated 05-Mar-2021) |
|
|
MalaCards organs/tissues related to Keratoconus 7:40
Eye
|
Articles related to Keratoconus 7:(show all 13)
|
Genes related to Keratoconus 7 (1 elite genes): - Elite gene
- Cancer Census gene in COSMIC
|
|
|
|
|
|