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MCID: KRT053
MIFTS: 15
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Keratoconus 7
Categories:
Genetic diseases, Rare diseases, Eye diseases
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MalaCards integrated aliases for Keratoconus 7:
Characteristics:HPO:32Classifications: |
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OMIM
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57
Keratoconus (KTCN) is a noninflammatory thinning and consequent bulging of the cornea that results in distortion of the corneal surface, altered refractive powers of the eye (both axial and refractive), and reduced visual acuity. In more advanced cases, corneal scarring further reduces visual acuity. Symptoms are highly variable and depend on the stage of the progression of the disorder. The trait has an incidence of approximately 1 in 2,000 individuals and is the most common indication for corneal transplantation in the United States (summary by Gajecka et al., 2009).
For a discussion of genetic heterogeneity of keratoconus, see KTCN1 (148300). (614629)
MalaCards based summary : Keratoconus 7, also known as ktcn7, is related to keratoconus. An important gene associated with Keratoconus 7 is KTCN7 (Keratoconus 7). Affiliated tissues include eye, and related phenotype is keratoconus. |
Diseases in the Keratoconus family:
Diseases related to Keratoconus 7 via text searches within MalaCards or GeneCards Suite gene sharing:
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Symptoms via clinical synopsis from OMIM:57Clinical features from OMIM:614629Human phenotypes related to Keratoconus 7:32
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MalaCards organs/tissues related to Keratoconus 7:41
Eye
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Genes related to Keratoconus 7 (1 elite genes):
- Elite gene
- Cancer Census gene in COSMIC
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