Keratomalacia (VAD)

Categories: Eye diseases, Metabolic diseases, Neuronal diseases, Rare diseases

Aliases & Classifications for Keratomalacia

Summaries for Keratomalacia

MedlinePlus : 42 Vitamins are substances that your body needs to grow and develop normally. Vitamin A plays a role in your Vision Bone growth Reproduction Cell functions Immune system Vitamin A is an antioxidant. It can come from plant or animal sources. Plant sources include colorful fruits and vegetables. Animal sources include liver and whole milk. Vitamin A is also added to foods like cereals. Vegetarians, young children, and alcoholics may need extra Vitamin A. You might also need more if you have certain conditions, such as liver diseases, cystic fibrosis, and Crohn's disease. Check with your health care provider to see if you need to take vitamin A supplements. NIH: National Institutes of Health Office of Dietary Supplements

MalaCards based summary : Keratomalacia, also known as vitamin a deficiency, is related to fundus albipunctatus and gyrate atrophy of choroid and retina, and has symptoms including photophobia, amaurosis fugax and metamorphopsia. An important gene associated with Keratomalacia is RHO (Rhodopsin), and among its related pathways/superpathways are Metabolism of fat-soluble vitamins and Visual Cycle in Retinal Rods. The drugs Dinoprostone and Goserelin have been mentioned in the context of this disorder. Affiliated tissues include bone, liver and endothelial, and related phenotype is vision/eye.

Wikipedia : 73 Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to... more...

Related Diseases for Keratomalacia

Diseases related to Keratomalacia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 983)
# Related Disease Score Top Affiliating Genes
1 fundus albipunctatus 32.0 TTR RHO LRAT
2 gyrate atrophy of choroid and retina 31.6 RHO LRAT
3 leber congenital amaurosis 2 31.5 RHO LRAT
4 xerophthalmia 31.0 TTR RHO RARS1 LRAT CYP26A1
5 intracranial hypertension, idiopathic 30.4 RBP4 RARA
6 night blindness 30.0 RHO RBP4 LRAT
7 hypervitaminosis a 29.7 TTR RBP4 RARS1 LRAT CYP26A1
8 acute promyelocytic leukemia 29.6 RARS1 RARB RARA CYP26A1
9 protein-energy malnutrition 29.5 TTR RBP4
10 ras-associated autoimmune leukoproliferative disorder 29.3 RBP4 RARS1 CYP26A1
11 squamous cell carcinoma, head and neck 29.3 RARS1 RARB RARA CYP26A1
12 microphthalmia, syndromic 9 29.2 RBP4 RARB LRAT CYP26A1
13 embryonal carcinoma 28.9 RARS1 RARB RARA CYP26A1
14 night blindness, congenital stationary, type 1a 11.9
15 x-linked congenital stationary night blindness 11.9
16 congenital stationary night blindness 11.8
17 night blindness, congenital stationary, type 1b 11.8
18 night blindness, congenital stationary, type 1e 11.8
19 night blindness, congenital stationary, type 2a 11.8
20 night blindness, congenital stationary, type 1d 11.8
21 night blindness, congenital stationary, type 1f 11.8
22 night blindness, congenital stationary, type 1h 11.8
23 night blindness, congenital stationary, autosomal dominant 2 11.8
24 night blindness, congenital stationary, type 1c 11.8
25 night blindness, congenital stationary, autosomal dominant 1 11.8
26 night blindness, congenital stationary, autosomal dominant 3 11.8
27 hypercarotenemia and vitamin a deficiency, autosomal dominant 11.7
28 oguchi disease 1 11.7
29 cone-rod synaptic disorder, congenital nonprogressive 11.7
30 night blindness, congenital stationary, type1i 11.7
31 night blindness, congenital stationary, type 1g 11.7
32 oguchi disease 2 11.7
33 autosomal recessive congenital stationary night blindness 11.7
34 oguchi disease 11.6
35 autosomal dominant congenital stationary night blindness 11.6
36 retinal cone dystrophy 3a 11.5
37 retinal cone dystrophy 3b 11.5
38 night blindness-skeletal anomalies-dysmorphism syndrome 11.5
39 acquired night blindness 11.3
40 choroideremia 11.3
41 enhanced s-cone syndrome 11.3
42 late-onset retinal degeneration 11.3
43 hereditary hypercarotenemia and vitamin a deficiency 11.2
44 retinitis pigmentosa 11.2
45 bietti crystalline corneoretinal dystrophy 11.2
46 retinitis pigmentosa 84 11.2
47 hypercarotenemia and vitamin a deficiency, autosomal recessive 11.2
48 cone-rod dystrophy 2 11.2
49 chondroectodermal dysplasia with night blindness 11.1
50 bothnia retinal dystrophy 11.1

Graphical network of the top 20 diseases related to Keratomalacia:

Diseases related to Keratomalacia

Symptoms & Phenotypes for Keratomalacia

UMLS symptoms related to Keratomalacia:

photophobia; amaurosis fugax; metamorphopsia; other specified visual disturbances; visual disturbance; subjective visual disturbance, unspecified; visual manifestations

MGI Mouse Phenotypes related to Keratomalacia:

# Description MGI Source Accession Score Top Affiliating Genes
1 vision/eye MP:0005391 9.17 LRAT RARA RARB RBP4 RHO SYDE1

Drugs & Therapeutics for Keratomalacia

Drugs for Keratomalacia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 956)
# Name Status Phase Clinical Trials Cas Number PubChem Id
Dinoprostone Approved Phase 4 363-24-6 5280360
Goserelin Approved Phase 4 65807-02-5 47725 5311128
Morphine Approved, Investigational Phase 4 57-27-2 5288826
Clobetasol Approved, Experimental, Investigational Phase 4 25122-41-2, 25122-46-7 32798 5311051
Interferon beta-1b Approved Phase 4 145155-23-3
Tibolone Approved, Investigational Phase 4 5630-53-5
Zinc Approved, Investigational Phase 4 7440-66-6 32051
BCG vaccine Approved, Investigational Phase 4
Lactulose Approved Phase 4 4618-18-2 11333
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
Racepinephrine Approved Phase 4 329-65-7 838
Copper Approved, Investigational Phase 4 7440-50-8 27099
Titanium dioxide Approved Phase 4 13463-67-7
Calcium carbonate Approved, Investigational Phase 4 471-34-1
Iodine Approved, Investigational Phase 4 7553-56-2 807
Ezetimibe Approved Phase 4 163222-33-1 150311
Pyrimethamine Approved, Investigational, Vet_approved Phase 4 58-14-0 4993
Sulfadoxine Approved, Investigational Phase 4 2447-57-6 17134
Albendazole Approved, Vet_approved Phase 4 54965-21-8 2082
Chromium Approved Phase 4 7440-47-3 27668
Molybdenum Approved Phase 4 7439-98-7 185498
Zoledronic Acid Approved Phase 4 118072-93-8 68740
Teriparatide Approved, Investigational Phase 4 52232-67-4 16133850
Risedronate Approved, Investigational Phase 4 105462-24-6 5245
Pentoxifylline Approved, Investigational Phase 4 6493-05-6 4740
Etidronic acid Approved Phase 4 7414-83-7, 2809-21-4 3305
Methyltestosterone Approved Phase 4 58-18-4 6010
Testosterone undecanoate Approved, Investigational Phase 4 5949-44-0
Testosterone enanthate Approved Phase 4 315-37-7 9416
30 Strontium ranelate Approved, Withdrawn Phase 4 135459-87-9
Nebivolol Approved, Investigational Phase 4 152520-56-4, 118457-14-0, 99200-09-6 71301
Atorvastatin Approved Phase 4 134523-00-5 60823
Losartan Approved Phase 4 114798-26-4 3961
Ferrous succinate Approved Phase 4 10030-90-7
Phenindione Approved, Investigational Phase 4 83-12-5 4760
fluindione Approved, Investigational Phase 4 957-56-2
Pregabalin Approved, Investigational Phase 4 148553-50-8 5486971
Amphotericin B Approved, Investigational Phase 4 1397-89-3 14956 5280965
Nifedipine Approved Phase 4 21829-25-4 4485
Montelukast Approved Phase 4 158966-92-8 5281040
Stavudine Approved, Investigational Phase 4 3056-17-5 18283
Adalimumab Approved, Experimental Phase 4 331731-18-1 16219006
Etanercept Approved, Investigational Phase 4 185243-69-0
Fluticasone Approved, Experimental Phase 4 90566-53-3 62924
Altretamine Approved Phase 4 645-05-6 2123
Bazedoxifene Approved, Investigational Phase 4 198481-32-2
Verapamil Approved Phase 4 52-53-9 2520
Ethinyl Estradiol Approved Phase 4 57-63-6 5991
Sage Approved Phase 4
Bisacodyl Approved Phase 4 603-50-9

Interventional clinical trials:

(show top 50) (show all 3591)
# Name Status NCT ID Phase Drugs
1 Maintenance of Vitamin D Sufficiency With Oral Vitamin D Supplementation in Malaysian Women of Malay and Indian Ethnicity With Post Menopausal Osteoporosis Unknown status NCT02389179 Phase 4 Vitamin D3
2 Study of Vitamin D2 Virus 1,25(OH)2-Vitamin D3 and Normal Protein Diet Virus Low Protein Diet in the Treatment of CKD-MBD and Malnutrition for Progressive CKD Patients Unknown status NCT02005302 Phase 4 1,25(OH)2 Vitamin D3;Vitamin D2
3 How Many Patients Are in Need of Vitamin B12 Injections? Unknown status NCT00326833 Phase 4 vitamin B12
4 Does Administration of Vitamin D in African Americans With Hypovitaminosis D and Type 2 DM Improve Inflammatory Markers of Cardiovascular Disease? Unknown status NCT01153243 Phase 4 Ergocalciferol;Placebo pill
5 Stability of Dental Implants Placed in Patients With Vitamin D Deficiency Using Sequential Drilling Versus a New One Single Drilling Design: A Randomized Clinical Trial Unknown status NCT03695562 Phase 4
6 Effects of Cholecalciferol on Osteoprotegerin Levels and Other Clinical Outcomes in Chronic Kidney Disease Patients on Peritoneal Dialysis: a Randomized Controlled Trial Unknown status NCT02598635 Phase 4 Cholecalciferol;Placebo
7 The Immune and Clinical Impacts of Vitamin D in Patients With Chronic Musculo-skeletal Pain Unknown status NCT01417923 Phase 4 vitamin D
8 The Impacts of Vitamin D Supplementation on Glucose Metabolism in Chinese Women With Vitamin D Deficiency and Former Gestational Diabetes Mellitus:A Randomised Control Trial Unknown status NCT03138616 Phase 4 vitamin D
9 Is Treatment of Vitamin D Deficiency Associated With Resolution of Statin-Induced Muscular Symptoms Unknown status NCT01568255 Phase 4 Ergocalciferol;Placebo
10 Correction of Vitamin D Deficiency to Prevent Postoperative Hypocalcemia After Thyroidectomy Unknown status NCT01632514 Phase 4 Cholecalciferol
11 Effect of Multi-vitamins With Minerals on Uric Acid Metabolism in Subjects With Hyperuricemia: A Randomized, Double-blinded, Placebo-controlled Trail Unknown status NCT03218709 Phase 4
12 Optimal Initial and Maintenance Doses of Ergocalciferol Supplementation for Treatment of Hypovitaminosis D in Thai Adults: A Randomized, Double-blinded Dose-comparison Study Unknown status NCT03228862 Phase 4 Ergocalciferol
13 Randomized Cross-Over Trial of Captafer® vs. Oral Iron Sulfate in the Treatment of Iron Deficiency Anemia in Patients With Inflammatory Bowel Disease Unknown status NCT02774057 Phase 4 Captafer®;Iron Sulfate
14 Eight Week Feasibility Study Enrolling Dry Eye Subjects Confirmed by Four of Seven Dianostic Markers Responding to Nutritional Therapy Unknown status NCT01561040 Phase 4
15 Clinical Trial, Open, Parallel Groups , Value the Antiproteinuric Effects From Vitamin D Derivatives in Patient With Chronic Kidney Illness and the Lack of Vitamin D Unknown status NCT01442272 Phase 4 Hidroferol®;Paricalcitol: Zemplar®;Habitual medication
16 Effect of Folic Acid, Vitamin B6 and Vitamin B12 in Diabetic Retinopathy Unknown status NCT01921192 Phase 4 Folic Acid, vit B6 and B12;Placebo
17 The Effect of a Nutrient Fortified Oat Drink on Iron, Zinc, Vitamin A, and Vitamin C Status Among Filipino Children Unknown status NCT01418898 Phase 4
18 The Assessment of the Effect of Vitamin D Supplementation on the Serum of AGES and Endothelialy Factors and Gene Expression of Glyoxalase Enzyme and YKL-40 Factor in PBMC Cells in the Patients With Type 2 Diabetes . Unknown status NCT03008057 Phase 4
19 Regulation of Bone Mineralization in Renal Osteodystrophy Unknown status NCT01799317 Phase 4 Vitamin D2
20 Influence of Vitamin K2 Administration on Vessel Calcification Markers in Patients With Chronic Kidney Disease Unknown status NCT01101698 Phase 4 Vitamin K2+10μg cholecalciferol;Vitamin D
21 The Impact of Vitamin on the Clinical Course in Cases Infected by Novel H1N1 Influenza Virus A: a Randomized-controlled Trial Unknown status NCT01127282 Phase 4 Vitamin (vitamin A 15 mg,C 500 mg, E 400IU);Placebo (digestive tablet)
22 Efficacy and Safety of Erythropoietin in the Treatment of Anemia in Patients With Lymphoma After Autologous Hematopoietic Stem Cell Transplantation Unknown status NCT03010579 Phase 4 erythropoietin;iron supplementation
23 Randomized Double Blinded Trial to Investigate Effects of an Enteral Nutritional Supplement Enriched With Eicosapentaenoic Acid on Body Composition,Complications,Stress Response,Immune Function & Quality of Life in After Esophagectomy Unknown status NCT00790140 Phase 4
24 Oxidative Stress In Semen And Male Infertility Unknown status NCT03464656 Phase 4 Fairhaven Pro for men
25 Evaluation of the Influence of Alendronate on Wound Healing After Dental Implants in Patients With Osteoporosis Unknown status NCT00727493 Phase 4 alendronate once weekly 70mg;placebo
26 Vitamin B6 Concentration and Treatment in Nausea and Vomiting of Pregnancy Unknown status NCT00763633 Phase 4 vitamin B6;vitamin B6
27 Vitamin D Concentrations and Their Effect on Glucose Metabolism in Pediatrics Unknown status NCT01386736 Phase 4 Vitamin D drops;Placebo drops
28 The Study of the Effects of Vitamin A Supplementation on Immune System and Th1/Th2 Balance in Patients With Atherosclerosis Unknown status NCT00963222 Phase 4 vitamin A;placebo
29 Impact of Vitamin A Supplementation on Disease Activity and Progression in Multiple Sclerotic (MS) Patients Unknown status NCT01417273 Phase 4 Drug: placebo
30 The Impact of Vitamin A Supplementation on Gene Expression of Cytokine Secreted by CD4+ T Lymphocyte in Multiple Sclerosis Patients Unknown status NCT01407211 Phase 4
31 Impact of Vitamin A Supplementation on RAR Gene Expression in PBMC Cells in Multiple Sclerotic Patients Unknown status NCT01705457 Phase 4 Dietary Supplement: vitamin A;placebo
32 The Effect of Vitamin A Supplementation on Gene Expression of Cytokine Secreted by T CD4+ Lymphocyte in Atherosclerotic Patients Unknown status NCT01414972 Phase 4 Vitamin A;placebo
33 The Effect of Vitamin A Supplementation on CD4+ T-cell Secretion in Obese Individuals Unknown status NCT01405352 Phase 4
34 Randomised Trial of Vitamin A Supplementation Given With Routine Childhood Vaccines at National Immunisation Days Unknown status NCT00168623 Phase 4 Vitamin A
35 Should Infants Receive High-dose Vitamin A Supplementation With BCG Vaccine at Birth in Developing Countries? Randomized Prospective Studies in Guinea-Bissau Unknown status NCT00168610 Phase 4 Vitamin A
36 Optimal Substitution Dose of the Vitamin D During Winter Time in Patient With Inflammatory Bowel Diseases (IBD) Unknown status NCT02958501 Phase 4 Colecalciferol
37 the Effect of Vitamin D on the Serum Thioredoxin, TBP-2, Thioredoxin Reductase, Gene Expression of TBP-2 in Patients With Type II Diabetes Unknown status NCT01876563 Phase 4
38 Comparisons of the Effect of Inactive and Active Vitamin D on Serum Sclerostin/dickkopf1 Levels Unknown status NCT01765010 Phase 4 Calcitriol;Alfacalcidol;Cholecalciferol;Placebo
39 Vitamin D Augmentation of Tekturna (Aliskiren) in Hypertension (VDATH) Unknown status NCT01472796 Phase 4 Tekturna(Aliskiren) plus placebo
40 Effect of Vitamin C Infusion on Coronary Reperfusion Indexes Unknown status NCT01090895 Phase 4 Vitamin C;Placebo
41 A Randomized, Multi-center, Phase IV Open-label Study Evaluating the Antiviral Efficacy of Addition of Vitamin D in Patients With Treatment Naïve Chronic Hepatitis C Receiving Peginterferon Alfa-2a Plus Ribavirin Unknown status NCT01439776 Phase 4
42 Effect of Vitamin D on Metabolic Parameters in Patients With the Metabolic Syndrome Unknown status NCT01237769 Phase 4 Vitamin D3
43 Vitamin D and Its Topical Analogues: A Possible Role in the Pathogenesis and Treatment of Acne Vulgaris Unknown status NCT03866447 Phase 4 Vitamin D analog;Adapalene
44 Vitamin D as an Adjunctive Treatment in Patients With Non-Cystic Fibrosis Bronchiectasis: a Double-blind Randomised Controlled Trial Unknown status NCT02507843 Phase 4 Cholecalciferol;Placebo
45 Intervention Study Measuring Inflammatory Cytokine Levels in the Serum of Patients Who Underwent an Acute MI, and the Influence of Vitamin D on These Levels Unknown status NCT01115842 Phase 4 Vitamin D
46 An Open-label Study of Combination of Cinacalcet and Active Vitamin D Analogue in the Management of Severe Secondary Hyperparathyroidism in Haemodialysis Patients Unknown status NCT02338934 Phase 4 Combination Cinacalcet with Vitamin D analogue
47 The Danish Non-vitamin K Antagonist Oral Anticoagulation Study. A Cluster Randomized Study Comparing Safety and Efficacy of Edoxaban, Apixaban, Rivaroxaban and Dabigatran for Oral Anticoagulation in Patients With Venous Thromboembolism. Unknown status NCT03129555 Phase 4 Dabigatran Etexilate Oral Capsule;Rivaroxaban Oral Tablet;Edoxaban Oral Tablet;Apixaban Oral Tablet
48 Providing Intravenous Paricalcitol Treatment to the Sick and Poor Chronic Hemodialysis Patients With Severe Secondary Hyperparathyroidism Resistant to Existing Vitamin D Analogs Unknown status NCT03023748 Phase 4 Intravenous Paricalcitol
49 Randomized Placebo Controlled Trial of Postoperative Pain After Intravenous Vitamin C Injection for Arthroscopic Rotator Cuff Repair Unknown status NCT02992028 Phase 4 Intravenous Nutrition (Vitamins) injection;Intravenous Saline injection
50 The Effect of Co-administered β-Carotene, Vitamin D3, Zinc and Antenatal Steroid Therapy on Hyaline Membrane Disease and Feeding Intolerance in Premature Neonates Unknown status NCT03366584 Phase 4 Dexamethasone

Search NIH Clinical Center for Keratomalacia

Inferred drug relations via UMLS 70 / NDF-RT 51 :

Cod Liver Oil
retinol acetate
retinyl palmitate
Vitamin A

Cochrane evidence based reviews: keratomalacia

Genetic Tests for Keratomalacia

Anatomical Context for Keratomalacia

MalaCards organs/tissues related to Keratomalacia:

Bone, Liver, Endothelial, Eye, Skin, Prostate, Ovary

Publications for Keratomalacia

Articles related to Keratomalacia:

(show top 50) (show all 3752)
# Title Authors PMID Year
Vitamin A supplementation prevents the bronchopulmonary dysplasia in premature infants: A systematic review and meta-analysis. 42
33545924 2021
Overlapping Vitamin A Intervention Programs: Should We Be Concerned with Excessive Intakes? 42
33021314 2020
Human Microfibrillar-Associated Protein 4 (MFAP4) Gene Promoter: A TATA-Less Promoter That Is Regulated by Retinol and Coenzyme Q10 in Human Fibroblast Cells. 42
33182307 2020
Chapter 29: historical aspects of the major neurological vitamin deficiency disorders: overview and fat-soluble vitamin A. 61 54
19892132 2010
Serum retinol binding protein as an indicator of vitamin A status in cirrhotic patients with night blindness. 61 54
19568486 2008
Effect of vitamin A supplementation with BCG vaccine at birth on vitamin A status at 6 wk and 4 mo of age. 54 61
17921381 2007
HIV-1 infection alters the retinol-binding protein:transthyretin ratio even in the absence of the acute phase response. 54 61
16702331 2006
Retinol-binding protein, transthyretin, and C-reactive protein in extremely low birth weight (ELBW) infants. 61 54
16208398 2005
[Protein profile and vitamin A in children of school age in Ivory Coast]. 61 54
15951260 2005
Possible pathomechanisms of sudden infant death syndrome: key role of chronic hypoxia, infection/inflammation states, cytokine irregularities, and metabolic trauma in genetically predisposed infants. 61 54
15543094 2004
Use of serum retinol-binding protein for prediction of vitamin A deficiency: effects of HIV-1 infection, protein malnutrition, and the acute phase response. 54 61
14749226 2004
Regulation of hepatic retinol metabolism: perspectives from studies on vitamin A status. 61 54
14704332 2004
Vitamin A transport: in vitro models for the study of RBP secretion. 61 54
14585312 2003
Retinoid receptors and vitamin A deficiency: differential patterns of transcription during early avian development and the rapid induction of RARs by retinoic acid. 61 54
12921748 2003
A comparison of three vitamin A dosing regimens in extremely-low-birth-weight infants. 54 61
12838194 2003
In vivo studies of altered expression patterns of p53 and proliferative control genes in chronic vitamin A deficiency and hypervitaminosis. 54 61
12654005 2003
Biochemical indicators of vitamin A deficiency: serum retinol and serum retinol binding protein. 54 61
12221267 2002
Assessment of vitamin A status of preschool children in Indonesia using plasma retinol-binding protein. 61 54
12022434 2002
Retinol binding protein as a surrogate measure for serum retinol: studies in vitamin A-deficient children from the Republic of the Marshall Islands. 61 54
11237937 2001
Use of the retinol-binding protein: transthyretin ratio for assessment of vitamin A status during the acute-phase response. 54 61
10953676 2000
Evaluation of plasma retinol-binding protein as a surrogate measure for plasma retinol concentrations. 54 61
10885491 2000
MMH cells: An in vitro model for the study of retinol-binding protein secretion regulated by retinol. 61 54
10457350 1999
Initial retinoid requirement for early avian development coincides with retinoid receptor coexpression in the precardiac fields and induction of normal cardiovascular development. 61 54
9786419 1998
A low molar ratio of retinol binding protein to transthyretin indicates vitamin A deficiency during inflammation: studies in rats and a posterior analysis of vitamin A-supplemented children with measles. 61 54
9772136 1998
Sequential evaluation of plasma retinol-binding protein response to vitamin A administration in very-low-birth-weight neonates. 61 54
7551819 1995
Effect of gestational age and retinol (vitamin A) deficiency on fetal rat lung nuclear retinoic acid receptors. 61 54
8384711 1993
Comparison of enteral and intramuscular vitamin A supplementation in preterm infants. 54 61
1493768 1992
Regulation of plasma retinol binding protein secretion in human HepG2 cells. 54 61
1315290 1992
Prevalence of malnutrition and vitamin A deficiency in the Diourbel, Fatick, and Kaolack regions of Senegal: a controlled study. 54 61
1898583 1991
Plasma retinol-binding protein response to vitamin A administration in infants susceptible to bronchopulmonary dysplasia. 54 61
2108233 1990
Regulation of metabolism of retinol-binding protein by vitamin A status in children with biliary atresia. 54 61
2321569 1990
Melting corneal ulcers (keratomalacia) in dogs: A 5-year clinical and microbiological study (2014-2018). 61
33794048 2021
Risk factors for anaemia among Ghanaian women and children vary by population group and climate zone. 61
32945623 2021
New cassava germplasm for food and nutritional security in Central Africa. 61
33795808 2021
Factors associated with coverage of vitamin a supplementation among Bangladeshi children: mixed modelling approach. 61
33794858 2021
Severe vitamin deficiencies in pregnancy complicated by progressive familial intrahepatic cholestasis. 61
33692058 2021
Starch digestibility and β-carotene bioaccessibility in the orange- fleshed sweet potato puree-wheat bread. 61
33565638 2021
Mechanisms of vitamin A metabolism and deficiency in the mammalian and fly visual system. 61
33774009 2021
Nutritional Deficiency Disease Secondary to ARFID Symptoms Associated with Autism and the Broad Autism Phenotype: A Qualitative Systematic Review of Case Reports and Case Series. 61
33221247 2021
Triad of hypovitaminosis A, hyperostosis, and optic neuropathy in males with autism spectrum disorders. 61
33666531 2021
Potential of pumpkin to combat vitamin A deficiency during complementary feeding in low and middle income countries: variety, provitamin A carotenoid content and retention, and dietary reference intakes. 61
33683154 2021
Macular thickness analysis and resolution of subretinal drusenoid deposits with optical coherence tomography in vitamin A deficiency-related retinopathy. 61
33644494 2021
Global patterns in vision loss burden due to Vitamin A deficiency from 1990 to 2017. 61
33775269 2021
Biological evidence to define a vitamin A deficiency cutoff using total liver vitamin A reserves. 61
33765844 2021
Vitamin A deficiency has declined in Malawi, but with evidence of elevated vitamin A in children. 61
33751046 2021
Re-Defining the Population-Specific Cut-Off Mark for Vitamin A Deficiency in Pre-School Children of Malawi. 61
33807563 2021
Is Treating Patients With Stage 4 Pressure Ulcers With Vitamins A and C, Zinc, and Arginine Justified? 61
33793413 2021
Chloroplast-to-chromoplast transition envisions provitamin A biofortification in green vegetables. 61
33754204 2021
The potential of utilizing Provitamin A-biofortified maize in producing mutwiwa, a Zimbabwean traditional fermented food. 61
33747466 2021
Does socio-economic inequality exist in micro-nutrients supplementation among children aged 6-59 months in India? Evidence from National Family Health Survey 2005-06 and 2015-16. 61
33740942 2021

Variations for Keratomalacia

Expression for Keratomalacia

Search GEO for disease gene expression data for Keratomalacia.

Pathways for Keratomalacia

GO Terms for Keratomalacia

Biological processes related to Keratomalacia according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 visual perception GO:0007601 9.69 RHO RBP4 LRAT
2 hormone-mediated signaling pathway GO:0009755 9.54 RARB RARA
3 ureteric bud development GO:0001657 9.52 RARB RARA
4 outflow tract septum morphogenesis GO:0003148 9.49 RARB RARA
5 regulation of myelination GO:0031641 9.48 RARB RARA
6 retinoic acid receptor signaling pathway GO:0048384 9.46 RARB RARA
7 negative regulation of cartilage development GO:0061037 9.43 RARB RARA
8 retinol metabolic process GO:0042572 9.43 TTR RBP4 LRAT
9 growth plate cartilage development GO:0003417 9.4 RARB RARA
10 ventricular cardiac muscle cell differentiation GO:0055012 9.37 RARB RARA
11 response to vitamin A GO:0033189 9.33 RARA LRAT CYP26A1
12 glandular epithelial cell development GO:0002068 9.32 RARB RARA
13 retinoid metabolic process GO:0001523 9.26 TTR RHO RBP4 LRAT
14 response to retinoic acid GO:0032526 8.92 RBP4 RARA LRAT CYP26A1

Molecular functions related to Keratomalacia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 9.16 RARB RARA
2 retinol binding GO:0019841 8.96 RBP4 LRAT
3 retinoic acid binding GO:0001972 8.8 RARA LRAT CYP26A1

Sources for Keratomalacia

9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
31 HPO
32 ICD10
33 ICD10 via Orphanet
37 LifeMap
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 05-Apr-2021)
61 PubMed
69 Tocris
71 UMLS via Orphanet
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