VAD
MCID: KRT002
MIFTS: 47

Keratomalacia (VAD)

Categories: Eye diseases, Rare diseases

Aliases & Classifications for Keratomalacia

MalaCards integrated aliases for Keratomalacia:

Name: Keratomalacia 12 75 53 55 44 15 72
Vitamin a Deficiency 53 55 72
Retinol Deficiency 53 72
Xerotic Keratitis 53 72
Night Blindness 53 72
Vitamin a 43
Vad 48

Classifications:

MalaCards categories:
Global: Rare diseases
Anatomical: Eye diseases


External Ids:

Disease Ontology 12 DOID:11267
ICD9CM 35 371.45
MeSH 44 C536156
SNOMED-CT 68 85149007
ICD10 33 H18.44
UMLS 72 C0028077 C0042842 C0152455 more

Summaries for Keratomalacia

MedlinePlus : 43 Vitamins are substances that your body needs to grow and develop normally. Vitamin A plays a role in your Vision Bone growth Reproduction Cell functions Immune system Vitamin A is an antioxidant. It can come from plant or animal sources. Plant sources include colorful fruits and vegetables. Animal sources include liver and whole milk. Vitamin A is also added to foods like cereals. Vegetarians, young children, and alcoholics may need extra Vitamin A. You might also need more if you have certain conditions, such as liver diseases, cystic fibrosis, and Crohn's disease. Check with your health care provider to see if you need to take vitamin A supplements. NIH: National Institutes of Health Office of Dietary Supplements

MalaCards based summary : Keratomalacia, also known as vitamin a deficiency, is related to xerophthalmia and phenylketonuria, and has symptoms including photophobia, amaurosis fugax and metamorphopsia. An important gene associated with Keratomalacia is RHO (Rhodopsin), and among its related pathways/superpathways are Visual Cycle in Retinal Rods and the visual cycle I (vertebrates). The drugs Ranibizumab and Racepinephrine have been mentioned in the context of this disorder. Affiliated tissues include liver, eye and testes, and related phenotype is Decreased viability with TRAIL.

Wikipedia : 75 Keratomalacia is an eye disorder that results from vitamin A deficiency. Vitamin A is required to... more...

Related Diseases for Keratomalacia

Diseases related to Keratomalacia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 1013)
# Related Disease Score Top Affiliating Genes
1 xerophthalmia 30.9 RHO DNASE1L1
2 phenylketonuria 29.4 TTR QDPR
3 congenital stationary night blindness 13.0
4 night blindness, congenital stationary, type 1a 13.0
5 night blindness, congenital stationary, type 1b 12.9
6 x-linked congenital stationary night blindness 12.9
7 night blindness, congenital stationary, type 2a 12.9
8 night blindness, congenital stationary, type 1e 12.9
9 night blindness, congenital stationary, type 1d 12.9
10 night blindness, congenital stationary, type 1f 12.9
11 night blindness, congenital stationary, autosomal dominant 2 12.9
12 night blindness, congenital stationary, type 1c 12.9
13 night blindness, congenital stationary, autosomal dominant 1 12.9
14 night blindness, congenital stationary, autosomal dominant 3 12.9
15 night blindness, congenital stationary, type 1h 12.9
16 night blindness, congenital stationary, type 1g 12.8
17 autosomal recessive congenital stationary night blindness 12.8
18 autosomal dominant congenital stationary night blindness 12.8
19 night blindness-skeletal anomalies-dysmorphism syndrome 12.6
20 acquired night blindness 12.5
21 hereditary hypercarotenemia and vitamin a deficiency 12.5
22 hypercarotenemia and vitamin a deficiency, autosomal recessive 12.5
23 oguchi disease 12.4
24 cone-rod synaptic disorder, congenital nonprogressive 12.4
25 oguchi disease 1 12.4
26 chondroectodermal dysplasia with night blindness 12.4
27 oguchi disease 2 12.4
28 retinal cone dystrophy 3a 12.0
29 retinal cone dystrophy 3b 12.0
30 fundus albipunctatus 11.8
31 choroideremia 11.7
32 late-onset retinal degeneration 11.7
33 enhanced s-cone syndrome 11.7
34 retinitis pigmentosa 11.6
35 cone-rod dystrophy 2 11.6
36 gyrate atrophy of choroid and retina 11.6
37 leber congenital amaurosis 2 11.4
38 melanoma-associated retinopathy 11.4
39 refsum disease, classic 11.4
40 goldmann-favre syndrome 11.4
41 bietti crystalline corneoretinal dystrophy 11.4
42 pagod syndrome 11.3
43 microphthalmia 11.3
44 bothnia retinal dystrophy 11.3
45 cone-rod dystrophy 16 11.3
46 abetalipoproteinemia 11.2
47 carotenemia 11.1
48 chylomicron retention disease 11.1
49 usher syndrome, type i 11.1
50 isotretinoin syndrome 11.1

Graphical network of the top 20 diseases related to Keratomalacia:



Diseases related to Keratomalacia

Symptoms & Phenotypes for Keratomalacia

UMLS symptoms related to Keratomalacia:


photophobia, amaurosis fugax, metamorphopsia, other specified visual disturbances, visual disturbance, subjective visual disturbance, unspecified, visual manifestations

GenomeRNAi Phenotypes related to Keratomalacia according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased viability with TRAIL GR00240-S-2 8.62 KALRN TTR

Drugs & Therapeutics for Keratomalacia

Drugs for Keratomalacia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show top 50) (show all 436)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Ranibizumab Approved Phase 4 347396-82-1 459903
2
Racepinephrine Approved Phase 4 329-65-7 838
3
Epinephrine Approved, Vet_approved Phase 4 51-43-4 5816
4
Ferrous fumarate Approved Phase 4 141-01-5
5
Albendazole Approved, Vet_approved Phase 4 54965-21-8 2082
6
chloroquine Approved, Investigational, Vet_approved Phase 4 54-05-7 2719
7
Nifedipine Approved Phase 4 21829-25-4 4485
8
Tazarotene Approved, Investigational Phase 4 118292-40-3 5381
9
Miconazole Approved, Investigational, Vet_approved Phase 4 22916-47-8 4189
10
Adapalene Approved Phase 4 106685-40-9 60164
11
Benzoyl peroxide Approved Phase 4 94-36-0 7187
12
Pyrantel Approved, Vet_approved Phase 4 15686-83-6
13
Methotrexate Approved Phase 4 1959-05-2, 59-05-2 126941
14
Acitretin Approved Phase 4 55079-83-9, 69427-46-9 6437841
15
Betamethasone Approved, Vet_approved Phase 4 378-44-9 9782
16
Nitroglycerin Approved, Investigational Phase 4 55-63-0 4510
17
Povidone Approved Phase 4 9003-39-8
18
Warfarin Approved Phase 4 81-81-2 6691 54678486
19
Azithromycin Approved Phase 4 83905-01-5 447043 55185
20
Dexamethasone Approved, Investigational, Vet_approved Phase 4 50-02-2 5743
21
Dexamethasone acetate Approved, Investigational, Vet_approved Phase 4 1177-87-3
22
Castor oil Approved, Investigational, Nutraceutical, Vet_approved Phase 4 8001-79-4
23
Calcitriol Approved, Nutraceutical Phase 4 32222-06-3 5280453 134070
24
Coumarin Experimental Phase 4 91-64-5 323
25
BCG vaccine Investigational Phase 4
26 polysaccharide-K Phase 4
27 Angiogenesis Inhibitors Phase 4
28 Angiogenesis Modulating Agents Phase 4
29 Adjuvants, Immunologic Phase 4
30 Epinephryl borate Phase 4
31 Respiratory System Agents Phase 4
32 Tubulin Modulators Phase 4
33 Anthelmintics Phase 4
34 Antimitotic Agents Phase 4
35 Chloroquine diphosphate Phase 4 50-63-5
36 Carbopol 940 Phase 4
37 arginine Phase 4
38 Tocolytic Agents Phase 4
39 calcium channel blockers Phase 4
40 Analgesics Phase 4
41 Anticoagulants Phase 4
42 Anti-Asthmatic Agents Phase 4
43 Lipid Regulating Agents Phase 4
44 Hypolipidemic Agents Phase 4
45 Antimetabolites Phase 4
46 Antirheumatic Agents Phase 4
47 Antifungal Agents Phase 4
48 Cathartics Phase 4
49 Castor Phase 4
50 Cyclosporins Phase 4

Interventional clinical trials:

(show top 50) (show all 440)
# Name Status NCT ID Phase Drugs
1 Should Infants Receive High-dose Vitamin A Supplementation With BCG Vaccine at Birth in Developing Countries? Randomized Prospective Studies in Guinea-Bissau Unknown status NCT00168610 Phase 4 Vitamin A
2 Randomised Trial of Vitamin A Supplementation Given With Routine Childhood Vaccines at National Immunisation Days Unknown status NCT00168623 Phase 4 Vitamin A
3 The Effect of Vitamin A Supplementation on Gene Expression of Cytokine Secreted by T CD4+ Lymphocyte in Atherosclerotic Patients Unknown status NCT01414972 Phase 4 Vitamin A;placebo
4 The Study of the Effects of Vitamin A Supplementation on Immune System and Th1/Th2 Balance in Patients With Atherosclerosis Unknown status NCT00963222 Phase 4 vitamin A;placebo
5 The Impact of Vitamin A Supplementation on Gene Expression of Cytokine Secreted by CD4+ T Lymphocyte in Multiple Sclerosis Patients Unknown status NCT01407211 Phase 4
6 Impact of Vitamin A Supplementation on RAR Gene Expression in PBMC Cells in Multiple Sclerotic Patients Unknown status NCT01705457 Phase 4 Dietary Supplement: vitamin A;placebo
7 The Effect of a Nutrient Fortified Oat Drink on Iron, Zinc, Vitamin A, and Vitamin C Status Among Filipino Children Unknown status NCT01418898 Phase 4
8 Impact of Vitamin A Supplementation on Disease Activity and Progression in Multiple Sclerotic (MS) Patients Unknown status NCT01417273 Phase 4 Drug: placebo
9 The Effect of Vitamin A Supplementation on CD4+ T-cell Secretion in Obese Individuals Unknown status NCT01405352 Phase 4
10 Effects of Ranibizumab to Delay or Regression Non-proliferative Diabetic Retinopathy(NPDR) With DME Assessed by Microaneurysm Changes: A Pilot Study Unknown status NCT02834663 Phase 4 Lucentis
11 The Impact of Vitamin on the Clinical Course in Cases Infected by Novel H1N1 Influenza Virus A: a Randomized-controlled Trial Unknown status NCT01127282 Phase 4 Vitamin (vitamin A 15 mg,C 500 mg, E 400IU);Placebo (digestive tablet)
12 Eight Week Feasibility Study Enrolling Dry Eye Subjects Confirmed by Four of Seven Dianostic Markers Responding to Nutritional Therapy Unknown status NCT01561040 Phase 4
13 Adrenal Cortical Function and Vitamin A Deficiency in Sepsis, Severe Sepsis and Septic Shock: Prospective Randomized, Double Blind Placebo Controlled Clinical Trials Completed NCT03152474 Phase 4 Solumedrol 20mg;Vitamin A 100,000 IU
14 Should Infants Receive High-dose Vitamin A Supplementation With BCG Vaccine at Birth in Developing Countries? Completed NCT00168597 Phase 4 Vitamin A
15 The Study of the Effects of Vitamin A Supplementation on Immune System and Th1/Th2 Balance in Patients With Multiple Sclerosis Completed NCT01225289 Phase 4 Placebo
16 Comparison of the Efficacy and Acceptability of Three Types of Micronutrient Supplements Added to Complementary Foods for Infants in Ghana Completed NCT00379158 Phase 4 Micronutrient supplements
17 Deworming and Enhanced Vitamin A Supplementation DEVTA Project Completed NCT00222547 Phase 4 Vitamin A;Albendazole
18 Effect of SLC30A8 rs13266634 Genetic Polymorphism on Zinc Supplementation and Glycemic Control in Egyptian Patients With Type 2 Diabetes Mellitus Completed NCT03112382 Phase 4 zinc supplement plus vitamin A and E;vitamin A and E
19 Randomised Study of the Impact of Different Doses of Vitamin A on Childhood Morbidity and Mortality Completed NCT00168584 Phase 4 Vitamin A
20 Vitamin A and Zinc: Prevention of Pneumonia (VAZPOP) Study Completed NCT00228254 Phase 4 Zinc (12.5 mg/day);vitamin A 10,000 IU per week
21 Does Additional Vitamin A Supplementation Improve Retinal Function and Conjunctival Health in Very Low Birthweight Infants? Completed NCT00417404 Phase 4 Aquasol A;aquasol A
22 The Impact of Different Doses of Vitamin A Supplementation on Male and Female Childhood Morbidity and Mortality Completed NCT00168636 Phase 4 Vitamin A
23 The Effect of Zinc, Beta-carotene, and Vitamin D3 Supplementation as Pro-inflammation Mediated Regulator in Preterm Delivery Through Placental Protein Adaptor MyD88 and TRIF, Transcription Factor NFkB, and Pro-inflammatory Cytokine IL-1β Completed NCT03005496 Phase 4 Zinc;Nifedipine;Beta Carotene;Vitamin D3;Dexamethasone
24 Chengdu Women's and Children's Central Hospital Completed NCT02675140 Phase 4 ZENTEL;ZENTEL and Vitamin A Soft Capsules
25 Discovery of Effects of Retinol on Human Skin Aging in Individuals of East Asian Descent Completed NCT02906566 Phase 4 Retinol;Placebo
26 Single Center, Open-Label, Efficacy and Safety Study of Tazarotene (Tazorac) for the Treatment of Brittle Nails Completed NCT00648986 Phase 4 Tazorac
27 Safety Study of the Use of Topical Cyclosporine in the Treatment of Dry Eye Disease Completed NCT02004067 Phase 4 Restasis;Refresh Endura
28 Effect of Sample Medication Use and Application Instructions on Adherence to and Efficacy of Treatment of Patients With Mild to Moderate Acne With Epiduo(R) Gel Completed NCT01504204 Phase 4 Adapalene + benzoyl peroxide samples;Adapalene + benzoyl peroxide from standard tube
29 Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso Completed NCT00642408 Phase 4
30 Longitudinal Study of Efficacy of Standard Albendazole Treatment Versus Levamisole/Pyrantel Pamoate on Soil Transmitted Helminth Infections Completed NCT00659997 Phase 4 Albendazole;Levamisole
31 Prevention of Intrauterine Growth Retardation in Hounde District, Burkina Faso: the Malaria Component Completed NCT00680732 Phase 4 Chloroquine (CQ);Sulphadoxyne-pyrimethamine (SP)
32 A Preliminary, Open Label, Single-arm Study to Determine the Efficacy of Taclonex Topical Suspension as a Supplement to Non-biologic Systemic Therapy Completed NCT01761019 Phase 4 Taclonex Topical Suspension
33 Effect of Prenatal Nutritional Supplementation on Birth Outcome in Hounde District, Burkina Faso Completed NCT00909974 Phase 4
34 Effect of Antioxidants on Ocular Blood Flow, Endothelial Function, and Cytokine Levels in LPS Induced Inflammatory Model in Humans. Completed NCT00431691 Phase 4 vitamin and mineral supplement;Escherichia coli Endotoxin (LPS);100% O2;nitroglycerin
35 Diarrhea, Malaria, Anemia, and Helminthiasis Prevention Through Household-based Interventions in Rural Western Kenya: the Nyando Integrated Child Health and Education (NICHE) Project Completed NCT01088958 Phase 4
36 A Comparative Randomized Controlled Study of Arginine Free Immunoenhancing Diet and Isocaloric, Isonitrogenous Formula in Critically Ill Patients Completed NCT01713257 Phase 4
37 Comparison of Autologous Serum Versus Preservative Free Artificial Tear in Patients With Dry Eye Due to Systemic Isotretinoin Therapy Completed NCT02752763 Phase 4 %40 diluted Autologous serum;Preservative free artificial tears(Tears naturale free, Refresh single dose eye drop)
38 Therapeutic Equivalence Between Branded and Generic Warfarin Sodium Tablets in Adult Patients With Atrial Fibrillation in Brazil - Crossover Randomized Controlled Equivalence Trial Completed NCT02017197 Phase 4 Marevan®;generic warfarin #1;generic warfarin #2
39 PRELIMINARY EVALUATION OF RETINAL EFFECTS OF PHARMACOLOLOGICAL LOWERING OF SERUM LEVES OF ADVANCED GLYCATION END-PRODUCTS (AGEs) IN TYPE 2 DIABETIC PATIENTS Completed NCT02249897 Phase 4 CHOLESTYRAMINE
40 Measles Vaccination in Guinea-Bissau. Strategies to Reduce Disease Burden and Improve Child Survival Completed NCT00168558 Phase 4
41 The Effect of Co-administered β-Carotene, Vitamin D3, Zinc and Antenatal Steroid Therapy on Hyaline Membrane Disease and Feeding Intolerance in Premature Neonates Recruiting NCT03366584 Phase 4 Dexamethasone
42 Neonates and Azithromycin, an Innovation in the Treatment of Children in Burkina Faso Recruiting NCT03682653 Phase 4 Azithromycin;Placebo
43 Community Health Azithromycin Trial in Burkina Faso Recruiting NCT03676764 Phase 4 Azithromycin;Placebos
44 Evaluating the Non-specific Effects of Different BCG Strains in Guinea-Bissau: Randomized Trial of the Impact on Early-life Hospital Admissions and Deaths Recruiting NCT03400878 Phase 4
45 Evaluation of the Impact on Mortality and Morbidity of the WHO Recommended Vitamin A Supplementation at First Immunisation Contact After 6 Months of Age Terminated NCT00514891 Phase 4
46 Intratracheal Vitamin A Administration With Surfactant for Newborn Respiratory Distress Syndrome Unknown status NCT01265589 Phase 3 surfactant;surfactant+vitamin A
47 Long-term Impact and Intervention for Diarrhea in Brazil Unknown status NCT00133406 Phase 3 Glutamine;Vitamin A;glycine;zinc
48 Efficacy of Consumption of Micronutrient Fortified Yoghurt on Biochemical Markers, Cognitive Development, Morbidity and Physical Growth Among 6-9 Years School Going Children in Bangladesh - A Double Masked, Randomized Trial With a Concurrent Matched Control Unknown status NCT00980733 Phase 3
49 Randomized Trial of Beta-Carotene and Macular Degeneration Unknown status NCT00000152 Phase 3 Aspirin;Beta-Carotene
50 Efficacy of β-carotene Biofortified Maize in Improving Vitamin A Status and Reducing the Prevalence of Vitamin A Deficiency Among Children in Rural Zambia Completed NCT01695148 Phase 3

Search NIH Clinical Center for Keratomalacia

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Cod Liver Oil
retinol acetate
retinyl palmitate
Vitamin A
VITAMIN A (AS ACETATE & BETA CAROTENE)
VITAMIN A (AS PALMITATE & BETA CAROTENE)
VITAMIN A (NATURAL)
VITAMIN A PALMITATE (SOLUBILIZED)

Cochrane evidence based reviews: keratomalacia

Genetic Tests for Keratomalacia

Anatomical Context for Keratomalacia

MalaCards organs/tissues related to Keratomalacia:

41
Liver, Eye, Testes, Lung, Bone, Breast, Skin

Publications for Keratomalacia

Articles related to Keratomalacia:

(show top 50) (show all 3558)
# Title Authors PMID Year
1
Vitamin A and D intake in pregnancy, infant supplementation, and asthma development: the Norwegian Mother and Child Cohort. 17
29722838 2018
2
Should universal distribution of high dose vitamin A to children cease? 17
29496673 2018
3
Serum levels of vitamin A and 25-hydroxyvitamin D3 (25OHD3) as reflectors of pulmonary function and quality of life (QOL) in children with stable asthma: A case-control study. 17
29443744 2018
4
Chapter 29: historical aspects of the major neurological vitamin deficiency disorders: overview and fat-soluble vitamin A. 9 38
19892132 2010
5
Control of Tissue-Resident Invariant NKT Cells by Vitamin A Metabolites and P2X7-Mediated Cell Death. 38
31308092 2019
6
Transcriptional responses to starvation stress in the hepatopancreas of oriental river prawn Macrobrachium nipponense. 38
31146228 2019
7
Reexamination of hemoglobin adjustments to define anemia: altitude and smoking. 38
31231812 2019
8
Vitamin A deficiency in critically ill children with sepsis. 38
31370866 2019
9
Night Blindness in Cystic Fibrosis: The Key Role of Vitamin A in the Digestive System. 38
31412557 2019
10
Relative Contributions of Malaria, Inflammation, and Deficiencies of Iron and Vitamin A to the Burden of Anemia during Low and High Malaria Seasons in Rural Zambian Children. 38
31402145 2019
11
Analysis of vitamin levels and deficiencies in bariatric surgery patients: a single-institutional analysis. 38
31202681 2019
12
Consumer Perceptions and Acceptability of Traditional Dishes Prepared with Provitamin A-Biofortified Maize and Sweet Potato. 38
31336921 2019
13
Causes and Management Outcomes of Acquired Corneal Opacity in a Preschool Age (0-5 Years) Group: A Hospital-Based Study. 38
31045962 2019
14
Tribal Odisha Eye Disease Study (TOES) report # 5: Comparison of prevalence and causes of visual impairment among tribal children in native and urban schools of Odisha (India). 38
31238398 2019
15
LncRNA-SULT1C2A regulates Foxo4 in congenital scoliosis by targeting rno-miR-466c-5p through PI3K-ATK signalling. 38
31044535 2019
16
The roles of retinoic acid in the differentiation of spermatogonia and spermatogenic disorders. 38
31302099 2019
17
Therapy-resistant dry itchy eyes. 38
31338612 2019
18
Dietary intake and micronutrient deficiency in children with cancer. 38
31286672 2019
19
Serum Retinol and Anemia in Women of Reproductive Age from Saint-Marc, Haiti (P02-008-19). 38
31224578 2019
20
Pattern of ocular morbidities: A cross-sectional study on school-going children in Shillong city. 38
31334191 2019
21
Effect of baseline micronutrient and inflammation status on CD4 recovery post-cART initiation in the multinational PEARLS trial. 38
29885777 2019
22
Improved micronutrient status and health outcomes in low- and middle-income countries following large-scale fortification: evidence from a systematic review and meta-analysis. 38
30997493 2019
23
Pancreatic lipase-related protein 2 is responsible for the increased hepatic retinyl ester hydrolase activity in vitamin A-deficient mice. 38
31199585 2019
24
Effect of Thermal Processing on Carotenoids and Folate Changes in Six Varieties of Sweet Potato (Ipomoes batata L.). 38
31213019 2019
25
Severe Vitamin a Deficiency After Biliopancreatic Diversion (P12-051-19). 38
31224587 2019
26
Metabolomics Investigation of Vitamin a Deficiency in a Rodent Model (P02-016-19). 38
31223831 2019
27
Case Report: Vitamin A Deficiency and Nyctalopia in a Patient with Chronic Pancreatitis. 38
31107845 2019
28
The Effect of Vitamin a Deficiency on Linear and Ponderal Growth in Sub-Saharan Africa (P10-015-19). 38
31223882 2019
29
Review on nutritional composition of orange-fleshed sweet potato and its role in management of vitamin A deficiency. 38
31289641 2019
30
Changing patterns of early childhood blinding conditions presenting to a tertiary eye center: The epidemic of retinopathy of prematurity in India. 38
31124493 2019
31
Complementary Feeding of Sorghum-Based and Corn-Based Fortified Blended Foods Results in Similar Iron, Vitamin A, and Anthropometric Outcomes in the MFFAPP Tanzania Efficacy Study. 38
31143849 2019
32
Resistin-like Molecule α Provides Vitamin-A-Dependent Antimicrobial Protection in the Skin. 38
31101494 2019
33
Variability of carotenoids in a Musa germplasm collection and implications for provitamin A biofortification. 38
31432011 2019
34
Does India Need a Universal High-Dose Vitamin A Supplementation Program? 38
30644040 2019
35
Lycopene cyclases determine high α-/β-carotene ratio and increased carotenoids in bananas ripening at high temperatures. 38
30722852 2019
36
Nutritional Properties and Consumer's Acceptance of Provitamin A-Biofortified Amahewu Combined with Bambara (Vigna Subterranea) Flour. 38
31261709 2019
37
Iron and Vitamin a Biomarkers in Mothers and Infants in Rural Uganda: Using the BRINDA Approach to Adjust for Inflammation (P10-108-19). 38
31224705 2019
38
Improving the Dietary Vitamin A Content of Rural Communities in South Africa by Replacing Non-Biofortified white Maize and Sweet Potato with Biofortified Maize and Sweet Potato in Traditional Dishes. 38
31141908 2019
39
Effects of vitamin A on growth performance and tissue retinol of starter White Pekin ducks. 38
30597070 2019
40
Cost-effectiveness of sunflower oil fortification with vitamin A in Tanzania by scale. 38
31148403 2019
41
Zinc and vitamin A deficiency in a cohort of children with autism spectrum disorder. 38
30821006 2019
42
Fortification of staple foods with vitamin A for vitamin A deficiency. 38
31074495 2019
43
Vitamin A levels are comparable between children with newly diagnosed coeliac disease and non-coeliac controls. 38
31124160 2019
44
Systematic review and meta-analysis approach on vitamin A fortified foods and its effect on retinol concentration in under 10 year children. 38
30904212 2019
45
Retinyl esters are elevated in progeny of retinol dehydrogenase 11 deficient dams. 38
30731079 2019
46
Vitamin A deficiency impairs intestinal physical barrier function of fish. 38
30716522 2019
47
The Ophthalmic Complications of Bariatric Surgery: The Role of Vitamin A Deficiency. 38
30919401 2019
48
Vitamin A deficiency execrates Lewis lung carcinoma via induction of type 2 innate lymphoid cells and alternatively activates macrophages. 38
31024701 2019
49
Prevalence and Risk Factors of Vitamin A Deficiency in Children and Women of Childbearing Age in a Southern Indian Tribal Population: A Cross-Sectional Study. 38
31333297 2019
50
Marginal Vitamin A Deficiency Affects the Expression Levels and Localization of Retinoic Acid Receptor and Retinoid X Receptor in Rats Meibomian Gland. 38
30512978 2019

Variations for Keratomalacia

Expression for Keratomalacia

Search GEO for disease gene expression data for Keratomalacia.

Pathways for Keratomalacia

Pathways related to Keratomalacia according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.13 TTR RHO
2
Show member pathways
10.36 TTR RHO
3 10.32 TTR RHO

GO Terms for Keratomalacia

Biological processes related to Keratomalacia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 retinoid metabolic process GO:0001523 8.62 TTR RHO

Molecular functions related to Keratomalacia according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 hormone activity GO:0005179 8.62 TTR APELA

Sources for Keratomalacia

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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