MCID: KRN007
MIFTS: 28

Kerion Celsi

Categories: Rare diseases, Skin diseases

Aliases & Classifications for Kerion Celsi

MalaCards integrated aliases for Kerion Celsi:

Name: Kerion Celsi 53 59 72
Trichophyton Infection 53 72
Susceptibility to Tinea Imbricata 53
Trichophytia Profunda Capitis 53
Trichophytia Profunda Barbae 53
Tinea Capitis Profunda 53
Tinea Capitis 72

Characteristics:

Orphanet epidemiological data:

59
kerion celsi
Inheritance: Not applicable; Age of onset: All ages; Age of death: normal life expectancy;

Classifications:

Orphanet: 59  
Rare skin diseases


External Ids:

MESH via Orphanet 45 C536165
ICD10 via Orphanet 34 B35.0
UMLS via Orphanet 73 C0276742
Orphanet 59 ORPHA499
UMLS 72 C0040250 C0276742 C0877265

Summaries for Kerion Celsi

MalaCards based summary : Kerion Celsi, also known as trichophyton infection, is related to dermatophytosis and tinea capitis. The drugs Griseofulvin and Terbinafine have been mentioned in the context of this disorder. Affiliated tissues include skin, liver and t cells, and related phenotypes are recurrent cutaneous abscess formation and fever

Related Diseases for Kerion Celsi

Diseases related to Kerion Celsi via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 15)
# Related Disease Score Top Affiliating Genes
1 dermatophytosis 11.0
2 tinea capitis 11.0
3 alopecia 10.8
4 panniculitis 10.5
5 tinea imbricata 10.4
6 thrombocytopenic purpura, autoimmune 10.4
7 hypomelanosis of ito 10.4
8 tinea corporis 10.4
9 tinea manuum 10.4
10 angioedema 10.4
11 purpura 10.4
12 respiratory allergy 9.9
13 allergic hypersensitivity disease 9.9
14 rhinitis 9.9
15 scabies 9.9

Graphical network of the top 20 diseases related to Kerion Celsi:



Diseases related to Kerion Celsi

Symptoms & Phenotypes for Kerion Celsi

Human phenotypes related to Kerion Celsi:

59 32 (show all 8)
# Description HPO Frequency Orphanet Frequency HPO Source Accession
1 recurrent cutaneous abscess formation 59 32 hallmark (90%) Very frequent (99-80%) HP:0100838
2 fever 59 32 frequent (33%) Frequent (79-30%) HP:0001945
3 alopecia 59 32 frequent (33%) Frequent (79-30%) HP:0001596
4 lymphadenopathy 59 32 frequent (33%) Frequent (79-30%) HP:0002716
5 myalgia 59 32 occasional (7.5%) Occasional (29-5%) HP:0003326
6 migraine 59 32 occasional (7.5%) Occasional (29-5%) HP:0002076
7 recurrent skin infections 59 Very frequent (99-80%)
8 inflammatory abnormality of the skin 59 Very frequent (99-80%)

Drugs & Therapeutics for Kerion Celsi

Drugs for Kerion Celsi (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 30)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Griseofulvin Approved, Investigational, Vet_approved Phase 3 126-07-8 441140
2
Terbinafine Approved, Investigational, Vet_approved Phase 3 91161-71-6 1549008 5402
3
Fluconazole Approved, Investigational Phase 3 86386-73-4 3365
4
Albendazole Approved, Vet_approved Phase 2, Phase 3 54965-21-8 2082
5 Papaya Approved Phase 2, Phase 3
6 Anti-Infective Agents Phase 2, Phase 3
7 14-alpha Demethylase Inhibitors Phase 3
8 Hormones Phase 3
9 Cytochrome P-450 CYP2C9 Inhibitors Phase 3
10 Cytochrome P-450 Enzyme Inhibitors Phase 3
11 Steroid Synthesis Inhibitors Phase 3
12 Cytochrome P-450 CYP2C19 Inhibitors Phase 3
13 Hormone Antagonists Phase 3
14 Hormones, Hormone Substitutes, and Hormone Antagonists Phase 3
15 Micronutrients Phase 2, Phase 3
16 Trace Elements Phase 2, Phase 3
17 Antiparasitic Agents Phase 2, Phase 3
18 Tubulin Modulators Phase 2, Phase 3
19 Anthelmintics Phase 2, Phase 3
20 Antiprotozoal Agents Phase 2, Phase 3
21 Antimitotic Agents Phase 2, Phase 3
22
Ciclopirox Approved, Investigational 29342-05-0 2749
23
Selenium Approved, Investigational, Vet_approved 7782-49-2
24
Ketoconazole Approved, Investigational 65277-42-1 47576
25 Cytochrome P-450 CYP3A Inhibitors
26 Selenium disulfide
27 Antioxidants
28 Protective Agents
29 Dermatologic Agents
30 Nutrients

Interventional clinical trials:

(show all 13)
# Name Status NCT ID Phase Drugs
1 A Pilot Study - Safety and Efficacy of Nailprotex® for Onychomycosis Treatment Completed NCT02464826 Phase 4 Nailprotex
2 Efficacy and Safety of Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117754 Phase 3 Terbinafine hydrochloride
3 An Open Label, Multicenter Trial Of Diflucan (Fluconazole) For 6 Weeks Given Once Daily To Pediatric Patients With Tinea Capitis Completed NCT00645242 Phase 3 fluconazole
4 Efficacy and Safety of Terbinafine Compared to Griseofulvin in Children With Tinea Capitis Completed NCT00117767 Phase 3 Terbinafine hydrochloride (HCl);Griseofulvin
5 Design and Clinical Evaluation of a School Meal With Deworming Properties Completed NCT02725255 Phase 2, Phase 3 Albendazole
6 Evaluation of Preclinical Toxicity of a Siddha Formulation Kandhaga Rasayanam ( KR ) and Its Therapeutic Efficacy in Padarthamarai ( Dermatophytoses ) by an Open Clinical Trial Completed NCT02238912 Phase 2 kandhaga rasayanam
7 A Double-Blind, Randomized, Vehicle-Control, Multicenter Study to Evaluate the Efficacy and Safety of NAFT900 in Children With Tinea Capitis Aged 6 to < 13 Years Withdrawn NCT02658292 Phase 2 Naftifine hydrochloride foam, 3%;Vehicle
8 Relevance of Trichoscopy in Differential Diagnosis of Focal Non-cicatricial Alopecia in Children Unknown status NCT03260777
9 Evaluation of Trichoscopy in the Diagnosis of Tinea Capitis. Prospective, Multicenter Study (ETDT) Completed NCT02550496
10 The Natural Course of Trichophyton Tonsurans Carriage and Infection: A Molecular and Biochemical Evaluation Completed NCT00224926
11 A Randomized, Double-Blinded, Placebo-Controlled Study Observing the Efficacy of Selenium Sulfide 1% Shampoo, Ketoconazole 2% Shampoo, and Ciclopirox 1% Shampoo as Adjunctive Treatments for Tinea Capitis in Children Completed NCT00127868 oral griseofulvin, selenium sulfide shampoo 1%, ciclopirox shampoo , ketoconazole shampoo 2%, baby shampoo
12 Carotid Atherosclerotic Disease Following Childhood Scalp Irradiation Completed NCT00590421
13 The Role of Trichoscopy in the Preliminary Diagnosis of Immunobollous Diseases Not yet recruiting NCT03478072

Search NIH Clinical Center for Kerion Celsi

Inferred drug relations via UMLS 72 / NDF-RT 51 :


Griseofulvin
Griseofulvin ultramicrosize
terbinafine
Terbinafine hydrochloride

Genetic Tests for Kerion Celsi

Anatomical Context for Kerion Celsi

MalaCards organs/tissues related to Kerion Celsi:

41
Skin, Liver, T Cells

Publications for Kerion Celsi

Articles related to Kerion Celsi:

(show top 50) (show all 109)
# Title Authors PMID Year
1
Tinea capitis in adults: A 18-year retrospective, single-centre study in Korea. 38
30980768 2019
2
Trichophyton tonsurans-induced kerion celsi with decreased defensin expression and paradoxically increased interleukin-17A production. 38
31294481 2019
3
Molecular diagnosis of kerion celsi caused by Trichophyton tonsurans in a Italian child. 38
31080711 2019
4
Itching in a trichophytin contact dermatitis mouse model and the antipruritic effect of antifungal agents. 38
30187507 2019
5
[Kerion Celsi]. 38
30869453 2018
6
Kerion celsi caused by Trichophyton tonsurans in a child. 38
29976531 2018
7
Fluctuating lesion of the scalp after a journey to the tropics: a case of furunculoid myiasis. 38
29630162 2018
8
[Acute skin infections and their imitators in children : A photo quiz]. 38
28914333 2017
9
Kerion Celsi with erythematous tumefaction on the groin due to Trichophyton mentagrophytes. 38
28757005 2017
10
Kerion celsi caused by Trichophyton erinacei from a hedgehog treated with terbinafine. 38
28869345 2017
11
Kerion Celsi due to Microsporum canis with a Dermatophytid Reaction. 38
28871931 2017
12
[A Case of Liver Dysfunction Requiring Hospital Admission after Taking Oral Itraconazole for the Treatment of Kerion Celsi]. 38
29187717 2017
13
[A baby with progressive skin lesions on the scalp]. 38
28659203 2017
14
Kerion Celsi Caused by Microsporum gypseum. 38
27567410 2016
15
[Trichophyton violaceum : Main cause of tinea capitis in children at Mbarara Regional Referral Hospital in Uganda]. 38
27341825 2016
16
[Trichophyton species of Arthroderma benhamiae : Clinical therapeutic aspects of a new pathogen in dermatology]. 38
27380384 2016
17
[Tinea in the genital area : A diagnostic and therapeutic challenge]. 38
27488308 2016
18
Kerion celsi: a misdiagnosed scalp infection. 38
26893521 2016
19
Glycyrrhetinic acid inhibits contact hypersensitivity induced by trichophytin via dectin-1. 38
26739065 2016
20
Successful treatment of severe kerion Celsi in an immunocompromised girl with evacuation of pus, terbinafine and short course glucocorticosteroids. 38
26852193 2016
21
Are Dermatophytid Reactions in Patients with Kerion Celsi Much More Common Than Previously Thought? A Prospective Study. 38
25677472 2015
22
Trichophyton tonsurans infection in Japan: epidemiology, clinical features, diagnosis and infection control. 38
25736317 2015
23
Kerion celsi of the vulva: an unusual location. 38
25459677 2014
24
The natural diyne-furan fatty acid EV-086 is an inhibitor of fungal delta-9 fatty acid desaturation with efficacy in a model of skin dermatophytosis. 38
24189258 2014
25
Pharmacological management of pediatric Kerion celsi. 38
24355234 2013
26
Remember kerion celsi. 38
24005974 2013
27
Erythema nodosum induced by kerion celsi of the scalp in a child: a case report and mini-review of literature. 38
23121556 2013
28
Kerion caused by Microsporum audouinii in a child. 38
24432216 2013
29
Successful use of silver impregnated hydrofiber dressing in the treatment of kerion celsi caused by Microsporum gypseum. 38
24476613 2013
30
Trichophyton mentagrophytes-associated Majocchi's granuloma treated with cryotherapy. 38
23042284 2012
31
Kerion celsi due to Arthroderma incurvatum infection in a Sri Lankan child: species identification and analysis of area-dependent genetic polymorphism. 38
22443310 2012
32
A case of Trichophyton mentagrophytes infection in a fennec fox (Vulpes zerda). 38
22822716 2012
33
Childhood erythema nodosum associated with kerion celsi: a case report and review of literature. 38
21692840 2012
34
Analysis of Trichophyton antigen-induced contact hypersensitivity in mouse. 38
22459756 2012
35
[Kerion celsi]. 38
22997774 2012
36
Images in clinical medicine. Kerion celsi. 38
22435373 2012
37
Accidental Trichophyton mentagrophytes fungemia during the course of kerion celsi. 38
21819454 2012
38
[Cutaneous mycoses in Japan originating from animals]. 38
22467127 2012
39
A retrospective study of the management of pediatric kerion in Trichophyton tonsurans infection. 38
22082462 2011
40
Severe kerion celsi due to Trichophyton mentagrophytes: a case report. 38
21382081 2011
41
[Dermatomycosis due to Trichophyton verrucosum in Sfax-Tunisia]. 38
24451562 2011
42
Erythema nodosum induced by kerion celsi of the scalp in a woman. 38
20113399 2011
43
[Protracted case of kerion Celsi in otherwise healthy seven year-old girl]. 38
21689510 2011
44
A case of kerion celsi caused by Microsporum gypseum in a boy following dermatoplasty for a scalp wound from a road accident. 38
20662636 2011
45
Neonatal kerion Celsi: report of three cases. 38
20653852 2010
46
Kerion Celsi favored by the use of a tretinoin+minoxidil+betamethasone valerate lotion in a 28-year-old woman. 38
20467404 2010
47
Inflammatory tinea capitis: kerion, dermatophytic granuloma, and mycetoma. 38
20347653 2010
48
Erythema nodosum complicating a case of kerion celsi of the scalp due to Trichophyton mentagrophytes. 38
19236422 2009
49
[Dermatophytosis: a summary of dermatomycosis as a proposal for future revision of the guidelines]. 38
19942789 2009
50
Case of kerion celsi caused by Microsporum gypseum (Arthroderma gypseum ) in a child. 38
19654448 2009

Variations for Kerion Celsi

Expression for Kerion Celsi

Search GEO for disease gene expression data for Kerion Celsi.

Pathways for Kerion Celsi

GO Terms for Kerion Celsi

Sources for Kerion Celsi

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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