Kidney Cortex Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Kidney Cortex Disease

MalaCards integrated aliases for Kidney Cortex Disease:

Name: Kidney Cortex Disease ¹² ¹⁵

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0080616

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Summaries for Kidney Cortex Disease

Disease Ontology : ¹² A kidney disease that is located in the kidney cortex.

MalaCards based summary : Kidney Cortex Disease is related to kidney cortex necrosis and pregnancy adenoma. An important gene associated with Kidney Cortex Disease is DICER1 (Dicer 1, Ribonuclease III), and among its related pathways/superpathways is Transcriptional misregulation in cancer. Affiliated tissues include kidney cortex, kidney and cortex.

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Related Diseases for Kidney Cortex Disease

Diseases related to Kidney Cortex Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 187)

#	Related Disease	Score	Top Affiliating Genes
1	kidney cortex necrosis	11.1
2	pregnancy adenoma	10.5	NTRK3 ETV6
3	microcystic stromal tumor	10.5	WT1 DICER1
4	breast secretory carcinoma	10.5	NTRK3 ETV6
5	lipid-rich carcinoma	10.5	NTRK3 ETV6
6	breast adenoid cystic carcinoma	10.5	NTRK3 ETV6
7	juvenile type testicular granulosa cell tumor	10.4	WT1 DICER1
8	testicular granulosa cell tumor	10.4	WT1 DICER1
9	wilms tumor predisposition	10.4	WT1 DICER1
10	differentiated thyroid carcinoma	10.4	NTRK3 ETV6 DICER1
11	pineal gland cancer	10.3	DICER1 BCOR
12	pulmonary blastoma	10.3	U2AF1 MIRLET7A1 DICER1
13	pleuropulmonary blastoma	10.3	U2AF1 MIRLET7A1 DICER1
14	cerebellar angioblastoma	10.3	WT1 NTRK3 ETV6
15	small cell sarcoma	10.3	CCNB3 BCOR
16	spermatic cord cancer	10.3	WT1 SSX2
17	chronic eosinophilic leukemia	10.3	WT1 U2AF1 ETV6
18	adult cystic nephroma	10.3	MME MEST
19	nephrogenic adenoma	10.3	KRT7 AMACR
20	cervical serous adenocarcinoma	10.3	WT1 MME
21	microinvasive cervical squamous cell carcinoma	10.3	WT1 KRT7
22	nephrogenic adenofibroma	10.3	WT1 KRT7
23	ovarian seromucinous carcinoma	10.3	WT1 KRT7
24	seminal vesicle adenocarcinoma	10.2	KRT7 AMACR
25	small cell osteogenic sarcoma	10.2	CCNB3 BCOR
26	bladder benign neoplasm	10.2	KRT7 AMACR
27	ossifying fibromyxoid tumor	10.2	CCNB3 BCOR
28	ovarian large-cell neuroendocrine carcinoma	10.2	WT1 KRT7
29	ovarian mucinous neoplasm	10.2	U2AF1 KRT7
30	ovarian mixed germ cell neoplasm	10.2	WT1 MME
31	malignant biphasic mesothelioma	10.2	WT1 KRT7
32	urethral diverticulum	10.2	KRT7 AMACR
33	benign mesothelioma	10.2	WT1 KRT7
34	ovarian brenner tumor	10.2	WT1 KRT7
35	pericardium cancer	10.2	WT1 KRT7
36	botryoid rhabdomyosarcoma	10.2	MYOG DICER1
37	liver leiomyosarcoma	10.2	WT1 KRT7
38	ovarian endometrioid stromal sarcoma	10.2	WT1 MME
39	glandular cystitis	10.2	KRT7 AMACR
40	endosalpingiosis	10.2	WT1 KRT7
41	renal pelvis carcinoma	10.2	PRCC KRT7
42	hobnail hemangioma	10.2	WT1 MYOG
43	middle ear carcinoma	10.2	WT1 KRT7
44	acinar cell carcinoma	10.1	NTRK3 KRT7 ETV6
45	tonsil cancer	10.1	NTRK3 KRT7 ETV6
46	oropharynx cancer	10.1	NTRK3 KRT7 ETV6
47	salivary gland disease	10.1	NTRK3 KRT7 ETV6
48	bladder adenocarcinoma	10.1	KRT7 AMACR
49	childhood acute lymphocytic leukemia	10.1	U2AF1 MME ETV6
50	sex cord-gonadal stromal tumor	10.1	WT1 KRT7 DICER1

Graphical network of the top 20 diseases related to Kidney Cortex Disease:

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Symptoms & Phenotypes for Kidney Cortex Disease

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Drugs & Therapeutics for Kidney Cortex Disease

Search Clinical Trials , NIH Clinical Center for Kidney Cortex Disease

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Genetic Tests for Kidney Cortex Disease

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Anatomical Context for Kidney Cortex Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Kidney Cortex Disease:

¹⁹

Kidney Cortex

MalaCards organs/tissues related to Kidney Cortex Disease:

⁴⁰

Kidney, Cortex

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Publications for Kidney Cortex Disease

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Genes for Kidney Cortex Disease

Genes related to Kidney Cortex Disease (0 elite genes):

(show all 17)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	DICER1	Dicer 1, Ribonuclease III	Protein Coding	8.11	DISEASES inferred ¹⁵
2	MEST	Mesoderm Specific Transcript	Protein Coding	7.61	DISEASES inferred ¹⁵
3	ETV6	ETS Variant Transcription Factor 6	Protein Coding	7.39	DISEASES inferred ¹⁵
4	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	7.31	DISEASES inferred ¹⁵
5	U2AF1	U2 Small Nuclear RNA Auxiliary Factor 1	Protein Coding	7.05	DISEASES inferred ¹⁵ ¹⁵
6	MIRLET7A1	MicroRNA Let-7a-1	RNA Gene	6.85	DISEASES inferred ¹⁵ ¹⁵
7	WT1	WT1 Transcription Factor	Protein Coding	6.74	DISEASES inferred ¹⁵
8	AMACR	Alpha-Methylacyl-CoA Racemase	Protein Coding	6.12	DISEASES inferred ¹⁵
9	PRCC	Proline Rich Mitotic Checkpoint Control Factor	Protein Coding	5.89	DISEASES inferred ¹⁵
10	BCOR	BCL6 Corepressor	Protein Coding	5.74	DISEASES inferred ¹⁵
11	CCNB3	Cyclin B3	Protein Coding	5.7	DISEASES inferred ¹⁵
12	NUTM2B	NUT Family Member 2B	Protein Coding	5.53	DISEASES inferred ¹⁵
13	SSX2	SSX Family Member 2	Protein Coding	5.52	DISEASES inferred ¹⁵
14	MME	Membrane Metalloendopeptidase	Protein Coding	5.5	DISEASES inferred ¹⁵
15	MYOG	Myogenin	Protein Coding	5.43	DISEASES inferred ¹⁵
16	SS18	SS18 Subunit Of BAF Chromatin Remodeling Complex	Protein Coding	5.42	DISEASES inferred ¹⁵
17	KRT7	Keratin 7	Protein Coding	5.31	DISEASES inferred ¹⁵

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Variations for Kidney Cortex Disease

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Expression for Kidney Cortex Disease

Search GEO for disease gene expression data for Kidney Cortex Disease.

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Pathways for Kidney Cortex Disease

Pathways related to Kidney Cortex Disease according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Transcriptional misregulation in cancer ³⁶	11.3	WT1 SSX2 SS18 PRCC ETV6

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GO Terms for Kidney Cortex Disease

Cellular components related to Kidney Cortex Disease according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	nuclear speck	GO:0016607	8.92	CCNB3 PRCC U2AF1 WT1

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Sources for Kidney Cortex Disease

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

⁶ ClinVar

⁷ CNVD

⁸ Cochrane Library

⁹ Cosmic

¹⁰ dbSNP

¹¹ DGIdb

¹² Disease Ontology

¹³ diseasecard

¹⁴ DiseaseEnhancer

¹⁵ DISEASES

¹⁶ DrugBank

¹⁷ EFO

¹⁸ ExPASy

¹⁹ FMA

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ Genetics Home Reference

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NIH Rare Diseases

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM

⁵⁷ OMIM via Orphanet

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

⁶³ QIAGEN

⁶⁴ R&D Systems

⁶⁵ Reactome

⁶⁶ Sino Biological

⁶⁷ SNOMED-CT

⁶⁸ SNOMED-CT via HPO

⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia