Kidney Cortex Disease disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

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Aliases & Classifications for Kidney Cortex Disease

MalaCards integrated aliases for Kidney Cortex Disease:

Name: Kidney Cortex Disease ¹² ¹⁵

Classifications:

MalaCards categories:
Anatomical: Nephrological diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹² DOID:0080616

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Summaries for Kidney Cortex Disease

Disease Ontology : ¹² A kidney disease that is located in the kidney cortex.

MalaCards based summary : Kidney Cortex Disease is related to kidney cortex necrosis and breast secretory carcinoma. An important gene associated with Kidney Cortex Disease is DICER1 (Dicer 1, Ribonuclease III), and among its related pathways/superpathways is Transcriptional misregulation in cancer. Affiliated tissues include kidney cortex, kidney and cortex, and related phenotype is no phenotypic analysis.

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Related Diseases for Kidney Cortex Disease

Diseases related to Kidney Cortex Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 236)

#	Related Disease	Score	Top Affiliating Genes
1	kidney cortex necrosis	11.0
2	breast secretory carcinoma	10.4	NTRK3 ETV6
3	microcystic stromal tumor	10.4	WT1 DICER1
4	mammary analogue secretory carcinoma	10.4	NTRK3 ETV6
5	juvenile type testicular granulosa cell tumor	10.3	WT1 DICER1
6	testicular granulosa cell tumor	10.3	WT1 DICER1
7	wilms tumor predisposition	10.3	WT1 DICER1
8	spermatic cord cancer	10.3	WT1 SSX2
9	differentiated thyroid carcinoma	10.3	NTRK3 ETV6 DICER1
10	cerebellar angioblastoma	10.3	WT1 NTRK3 ETV6
11	pleuropulmonary blastoma	10.3	U2AF1 MIRLET7A1 DICER1
12	chronic eosinophilic leukemia	10.2	WT1 U2AF1 ETV6
13	ovarian mixed germ cell neoplasm	10.2	WT1 MME
14	pregnancy adenoma	10.2	PGR NTRK3
15	botryoid rhabdomyosarcoma	10.2	MYOG DICER1
16	kidney rhabdoid cancer	10.2	NUTM2B CCNB3
17	kidney fibrosarcoma	10.2	SSX2 NTRK3 ETV6
18	hobnail hemangioma	10.2	WT1 MYOG
19	malignant glandular tumor of peripheral nerve sheath	10.2	SSX2 MYOG
20	heart sarcoma	10.1	SSX2 MYOG
21	adult fibrosarcoma	10.1	NTRK3 MYOG ETV6
22	breast adenoid cystic carcinoma	10.1	PGR NTRK3 ETV6
23	lipid-rich carcinoma	10.1	PGR NTRK3 ETV6
24	cervical adenomyoma	10.1	PGR MME
25	cervical benign neoplasm	10.1	PGR MME
26	central nervous system mesenchymal non-meningothelial tumor	10.1	NUTM2B MYOG
27	retroperitoneal sarcoma	10.1	SSX2 MYOG
28	uterine corpus adenosarcoma	10.1	PGR MME
29	breast leiomyoma	10.1	PGR MME
30	fallopian tube endometriosis	10.1	PGR MME
31	congenital fibrosarcoma	10.1	NTRK3 MYOG ETV6
32	cervical carcinosarcoma	10.1	MYOG MME
33	kidney clear cell sarcoma	10.1	NUTM2B NTRK3 CCNB3
34	malignant mesenchymoma	10.1	SSX2 MYOG
35	lung combined type small cell carcinoma	10.1	MYOG MME
36	mucocele of appendix	10.1	PGR MME
37	askin's tumor	10.1	MYOG CCNB3
38	heart lymphoma	10.1	MYOG MME
39	adult cystic nephroma	10.1	PGR MME
40	kidney hemangiopericytoma	10.1	SSX2 SS18
41	intravenous leiomyomatosis	10.1	PGR MME
42	meninges sarcoma	10.1	SSX2 SS18
43	clear cell sarcoma	10.1	WT1 NUTM2B CCNB3
44	vaginal endometrial stromal sarcoma	10.1	PGR MME
45	vulvar leiomyoma	10.1	PGR MME
46	breast malignant phyllodes tumor	10.1	PGR MME
47	mental retardation, autosomal dominant 33	10.1	MME ETV6
48	uterine corpus cancer	10.1	WT1 U2AF1 PGR
49	benign breast phyllodes tumor	10.1	PGR MME
50	prostate sarcoma	10.1	PGR MYOG

Graphical network of the top 20 diseases related to Kidney Cortex Disease:

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Symptoms & Phenotypes for Kidney Cortex Disease

MGI Mouse Phenotypes related to Kidney Cortex Disease:

⁴⁶

#	Description	MGI Source Accession	Score	Top Affiliating Genes
1	no phenotypic analysis	MP:0003012	9.1	DICER1 ETV6 MYOG NTRK3 PGR WT1

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Drugs & Therapeutics for Kidney Cortex Disease

Search Clinical Trials , NIH Clinical Center for Kidney Cortex Disease

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Genetic Tests for Kidney Cortex Disease

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Anatomical Context for Kidney Cortex Disease

The Foundational Model of Anatomy Ontology organs/tissues related to Kidney Cortex Disease:

¹⁹

Kidney Cortex

MalaCards organs/tissues related to Kidney Cortex Disease:

⁴⁰

Kidney, Cortex

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Publications for Kidney Cortex Disease

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Genes for Kidney Cortex Disease

Genes related to Kidney Cortex Disease (0 elite genes):

(show all 16)

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	DICER1	Dicer 1, Ribonuclease III	Protein Coding	8.07	DISEASES inferred ¹⁵
2	ETV6	ETS Variant Transcription Factor 6	Protein Coding	7.36	DISEASES inferred ¹⁵
3	NTRK3	Neurotrophic Receptor Tyrosine Kinase 3	Protein Coding	7.29	DISEASES inferred ¹⁵
4	U2AF1	U2 Small Nuclear RNA Auxiliary Factor 1	Protein Coding	6.94	DISEASES inferred ¹⁵ ¹⁵
5	MIRLET7A1	MicroRNA Let-7a-1	RNA Gene	6.75	DISEASES inferred ¹⁵ ¹⁵
6	WT1	WT1 Transcription Factor	Protein Coding	6.64	DISEASES inferred ¹⁵
7	MEST	Mesoderm Specific Transcript	Protein Coding	6.46	DISEASES inferred ¹⁵
8	AMACR	Alpha-Methylacyl-CoA Racemase	Protein Coding	6.05	DISEASES inferred ¹⁵
9	CCNB3	Cyclin B3	Protein Coding	5.65	DISEASES inferred ¹⁵
10	SSX2	SSX Family Member 2	Protein Coding	5.49	DISEASES inferred ¹⁵
11	NUTM2B	NUT Family Member 2B	Protein Coding	5.47	DISEASES inferred ¹⁵
12	MME	Membrane Metalloendopeptidase	Protein Coding	5.45	DISEASES inferred ¹⁵
13	MYOG	Myogenin	Protein Coding	5.38	DISEASES inferred ¹⁵
14	SS18	SS18 Subunit Of BAF Chromatin Remodeling Complex	Protein Coding	5.37	DISEASES inferred ¹⁵
15	KRT7	Keratin 7	Protein Coding	5.25	DISEASES inferred ¹⁵
16	PGR	Progesterone Receptor	Protein Coding	5.24	DISEASES inferred ¹⁵

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Variations for Kidney Cortex Disease

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Expression for Kidney Cortex Disease

Search GEO for disease gene expression data for Kidney Cortex Disease.

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Pathways for Kidney Cortex Disease

Pathways related to Kidney Cortex Disease according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Transcriptional misregulation in cancer ³⁶	11.21	WT1 SSX2 SS18 ETV6

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GO Terms for Kidney Cortex Disease

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Sources for Kidney Cortex Disease

¹ BioSystems

² BitterDB

³ CDC

⁴ Cell Signaling Technology

⁵ ClinicalTrials

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¹⁰ dbSNP

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¹⁶ DrugBank

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²¹ GeneAnalytics

²² GeneCards

²³ GeneGo (Thomson Reuters)

²⁴ GeneHancer via GeneCards

²⁵ GeneReviews

²⁶ GenomeRNAi

²⁷ GEO DataSets

²⁸ GO

²⁹ GTR

³⁰ HMDB

³¹ HPO

³² ICD10

³³ ICD10 via Orphanet

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ KEGG

³⁷ LifeMap

³⁸ LncRNADisease

³⁹ LOVD

⁴⁰ MalaCards

⁴¹ MedGen

⁴² MedlinePlus

⁴³ MedlinePlus Genetics

⁴⁴ MeSH

⁴⁵ MESH via Orphanet

⁴⁶ MGI

⁴⁷ miR2Disease

⁴⁸ NCBI Bookshelf

⁴⁹ NCI

⁵⁰ NCIt

⁵¹ NDF-RT

⁵² NIH Clinical Center

⁵³ NINDS

⁵⁴ Novoseek

⁵⁵ Novus Biologicals

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 05-Mar-2021)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubMed

⁶² PubMed Health

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⁶⁴ R&D Systems

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⁶⁷ SNOMED-CT

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⁶⁹ TGDB

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ Wikipedia