MCID: KDN019
MIFTS: 27

Kidney Sarcoma

Categories: Cancer diseases, Nephrological diseases

Aliases & Classifications for Kidney Sarcoma

MalaCards integrated aliases for Kidney Sarcoma:

Name: Kidney Sarcoma 12 15
Sarcoma of Kidney 12 70
Renal Sarcoma 12 29

Classifications:



External Ids:

Disease Ontology 12 DOID:4242
NCIt 50 C4525
SNOMED-CT 67 254918001
UMLS 70 C0346251

Summaries for Kidney Sarcoma

Disease Ontology : 12 A kidney cancer that is located in the kidney's connective tissue.

MalaCards based summary : Kidney Sarcoma, also known as sarcoma of kidney, is related to kidney clear cell sarcoma and nephroma. An important gene associated with Kidney Sarcoma is NUTM2B (NUT Family Member 2B), and among its related pathways/superpathways are Transcriptional misregulation in cancer and Cell cycle Role of 14-3-3 proteins in cell cycle regulation. Affiliated tissues include kidney, myeloid and uterus.

Related Diseases for Kidney Sarcoma

Diseases related to Kidney Sarcoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 107)
# Related Disease Score Top Affiliating Genes
1 kidney clear cell sarcoma 30.5 YWHAE VGLL2 TLE1 SATB2 NUTM2E NUTM2B
2 nephroma 29.7 WT1 DICER1
3 clear cell sarcoma 29.6 YWHAE WT1 NUTM2E NUTM2B CCNB3
4 kidney fibrosarcoma 29.6 YWHAE SSX2 SSX1
5 rhabdoid cancer 29.4 WT1 SSX2 SS18
6 sarcoma 29.1 WT1 SSX2 SSX1 SS18 DICER1
7 monophasic synovial sarcoma 29.1 TLE1 SSX2 SSX1 SS18
8 spindle cell sarcoma 29.1 VGLL2 TLE1 SSX2 SSX1 SS18 CCNB3
9 rhabdomyosarcoma 29.0 WT1 VGLL2 SSX2 SSX1 DICER1
10 ewing sarcoma 29.0 WT1 TLE1 SSX1 SS18 CCNB3
11 sarcoma, synovial 28.7 WT1 TLE1 SSX2 SSX1 SS18 CCNB3
12 rhabdomyosarcoma 2 28.3 WT1 VGLL2 SSX2 SSX1 SS18 CCNB3
13 kidney leiomyosarcoma 11.0
14 kidney osteogenic sarcoma 10.9
15 central nervous system mesenchymal non-meningothelial tumor 10.3 NUTM2E NUTM2B
16 malignant glandular tumor of peripheral nerve sheath 10.2 TLE1 SSX2
17 leiomyosarcoma 10.2
18 small cell osteogenic sarcoma 10.2 SATB2 CCNB3
19 kidney rhabdoid cancer 10.2 YWHAE NUTM2B CCNB3
20 endometrial stromal tumor 10.1 YWHAE NUTM2B CCNB3
21 kidney hemangiopericytoma 10.1 SSX2 SS18
22 tibial adamantinoma 10.1 TLE1 SSX1
23 meninges sarcoma 10.1 SSX2 SS18
24 mediastinal mesenchymal tumor 10.1 TLE1 SS18
25 conventional central osteosarcoma 10.1 SATB2 CCNB3
26 heart sarcoma 10.1 SSX2 SSX1
27 adamantinoma of long bones 10.1 TLE1 SSX1
28 lung sarcoma 10.1 SSX2 SSX1
29 pediatric fibrosarcoma 10.1 VGLL2 CCNB3
30 liposarcoma 10.1
31 endometrial stromal sarcoma 10.1 YWHAE NUTM2B CCNB3
32 ovarian endometrioid stromal sarcoma 10.1 YWHAE WT1
33 extraosseous osteosarcoma 10.0 SSX1 SATB2
34 extraosseous chondrosarcoma 10.0 SSX2 SS18
35 microcystic stromal tumor 10.0 WT1 DICER1
36 ovary sarcoma 10.0 YWHAE WT1
37 juvenile type testicular granulosa cell tumor 10.0 WT1 DICER1
38 testicular granulosa cell tumor 10.0 WT1 DICER1
39 core binding factor acute myeloid leukemia 10.0 WT1 TLE1
40 mesenchymal cell neoplasm 10.0 SSX2 CCNB3
41 ovarian sex-cord stromal tumor 10.0 WT1 DICER1
42 wilms tumor predisposition 10.0 WT1 DICER1
43 pleomorphic liposarcoma 10.0 SSX2 SS18
44 cellular schwannoma 10.0 SSX1 SS18
45 malignant fibrous histiocytoma 10.0
46 fibrous histiocytoma 10.0
47 epithelioid malignant peripheral nerve sheath tumor 10.0 TLE1 SSX2 SS18
48 myxofibrosarcoma 9.9 TLE1 SSX2 SS18
49 kidney benign neoplasm 9.9 WT1 DICER1
50 renal cell carcinoma, nonpapillary 9.9

Graphical network of the top 20 diseases related to Kidney Sarcoma:



Diseases related to Kidney Sarcoma

Symptoms & Phenotypes for Kidney Sarcoma

Drugs & Therapeutics for Kidney Sarcoma

Search Clinical Trials , NIH Clinical Center for Kidney Sarcoma

Genetic Tests for Kidney Sarcoma

Genetic tests related to Kidney Sarcoma:

# Genetic test Affiliating Genes
1 Renal Sarcoma 29

Anatomical Context for Kidney Sarcoma

MalaCards organs/tissues related to Kidney Sarcoma:

40
Kidney, Myeloid, Uterus, T Cells, Cortex, Heart, Skeletal Muscle

Publications for Kidney Sarcoma

Articles related to Kidney Sarcoma:

(show top 50) (show all 76)
# Title Authors PMID Year
1
Immunophenotype-Genotype Correlations in Clear Cell Sarcoma of Kidney-An Evaluation of Diagnostic Ancillary Studies. 61
32364435 2020
2
BCOR Overexpression in Renal Malignant Solitary Fibrous Tumors: A Close Mimic of Clear Cell Sarcoma of Kidney. 61
30864973 2019
3
Paraneoplastic hepatic dysfunction with jaundice in a case of primary renal synovial sarcoma: A very rare scenario. 61
31211052 2019
4
Expression of cyclin D1 in clear cell sarcoma of kidney. Is it useful in differentiating it from its histological mimics? 61
30736802 2019
5
Ewing's sarcoma of kidney in a 60-year-old patient with local recurrence: A rare occurrence. 61
30488867 2018
6
Primary Low-Grade Fibromyxoid Sarcoma of Kidney-an Extremely Rare Entity. 61
29973762 2018
7
Delayed Metastasis of Clear Cell Sarcoma of Kidney to Bladder After 7 Disease-Free Years. 61
29509095 2018
8
Primary Renal Sarcomas With BCOR-CCNB3 Gene Fusion: A Report of 2 Cases Showing Histologic Overlap With Clear Cell Sarcoma of Kidney, Suggesting Further Link Between BCOR-related Sarcomas of the Kidney and Soft Tissues. 61
28817404 2017
9
Clear cell sarcoma of kidney involving a horseshoe kidney and harboring EGFR internal tandem duplication. 61
28440018 2017
10
FNAC aided diagnosis of clear cell sarcoma of kidney: Report of two cases in infants. 61
28421721 2017
11
Recurrent BCOR internal tandem duplication and BCOR or BCL6 expression distinguish primitive myxoid mesenchymal tumor of infancy from congenital infantile fibrosarcoma. 61
28256570 2017
12
Renal Clear Cell Sarcoma - Anaplastic Variant: A Rare Entity. 61
28273978 2017
13
Dual tumor - Clear cell sarcoma of kidney with differentiating neuroblastoma: A rare case with review of literature. 61
28195106 2017
14
Concurrent occurrence of neuroblastoma and clear cell sarcoma of kidney in an infant: Is it a random event? 61
28195107 2017
15
BCOR Overexpression Is a Highly Sensitive Marker in Round Cell Sarcomas With BCOR Genetic Abnormalities. 61
27428733 2016
16
Primary Synovial Sarcoma of the Kidney with Inferior Vena Caval Thrombus. 61
27651698 2016
17
Recurrent BCOR Internal Tandem Duplication and YWHAE-NUTM2B Fusions in Soft Tissue Undifferentiated Round Cell Sarcoma of Infancy: Overlapping Genetic Features With Clear Cell Sarcoma of Kidney. 61
26945340 2016
18
Tumor progression in DICER1-mutated cystic nephroma-witnessing the genesis of anaplastic sarcoma of the kidney. 61
27036314 2016
19
Evolution of Renal Cysts to Anaplastic Sarcoma of Kidney in a Child With DICER1 Syndrome. 61
26928971 2016
20
Synovial sarcoma of kidney in a child: A rare presentation. 61
27046979 2016
21
Mutually exclusive BCOR internal tandem duplications and YWHAE-NUTM2 fusions in clear cell sarcoma of kidney: not the full story. 61
27000436 2016
22
[Clear cell sarcoma of kidney in children]. 61
26927827 2016
23
Clear cell sarcoma of the kidney: report of two cases. 61
25374799 2014
24
Clear cell sarcoma of kidney in a neonate. 61
26023506 2014
25
Malignant renal tumors in childhood: report of 54 cases treated at a single institution. 61
24279977 2014
26
Primary synovial sarcoma of kidney: a rare differential diagnosis of renomegaly. 61
25610686 2014
27
Rapidly progressive course of primary renal synovial sarcoma--case report. 61
24502105 2013
28
Outcomes of patients with revised stage I clear cell sarcoma of kidney treated in National Wilms Tumor Studies 1-5. 61
22658515 2013
29
Clear cell sarcoma of kidney: morphoproteomic analysis reveals genomic correlates and therapeutic options. 61
22256788 2013
30
Metanephric stromal tumour: A rare pediatric benign stromal specific renal neoplasm. 61
23671366 2013
31
Primary Ewing sarcoma of kidney in an elderly. 61
22797102 2012
32
Characterization of the chromosomal translocation t(10;17)(q22;p13) in clear cell sarcoma of kidney. 61
22294382 2012
33
Primary renal synovial sarcoma. 61
24765443 2012
34
Nonleukemic granulocytic sarcoma of kidney with mixed phenotype blasts: a diagnostic dilemma. 61
21934235 2011
35
Clear cell sarcoma of kidney: A rare entity. 61
22557783 2011
36
Renal tumors in children aged 10-16 Years: a report from the United Kingdom Children's Cancer and Leukaemia Group. 61
21054158 2011
37
Primary synovial sarcoma of kidney-a report of 2 cases and review of literature. 61
21863065 2010
38
Pulmonary metastasis from renal synovial sarcoma treated by stereotactic body radiotherapy: a case report and review of the literature. 61
20479551 2010
39
[Fibromyxoid sarcoma of kidney]. 61
19925768 2009
40
Primary synovial sarcoma of kidney: A rare tumor with an atypical presentation. 61
19672366 2009
41
Malignant renal tumours incidence and survival in European children (1978-1997): report from the Automated Childhood Cancer Information System project. 61
16919774 2006
42
Translocation (10;17)(q22;p13): a recurring translocation in clear cell sarcoma of kidney. 61
15474157 2004
43
Transfer of IFNgamma-depleted CD4(+) T cells together with CD8(+) T cells leads to rejection of murine kidney sarcoma in mice. 61
10925361 2000
44
Clear cell sarcoma of kidney in an adolescent and in young adults: a report of four cases with ultrastructural, immunohistochemical, and DNA flow cytometric analysis. 61
10584698 1999
45
[Clear cell renal carcinoma outside of the usual age group]. 61
10584353 1999
46
Clear cell sarcoma kidney: clinical features and outcome. 61
10100278 1999
47
Clear cell sarcoma of kidney with tumor extension into the right atrium. 61
9788798 1998
48
Cystic embryonal sarcoma of kidney: a case report. 61
9635536 1998
49
Veno-occlusive disease-like hepatotoxicity in two children receiving chemotherapy for Wilms' tumor and clear cell sarcoma of kidney. 61
9509511 1998
50
[Clear cell sarcoma of the kidney in a young adult]. 61
9526626 1997

Variations for Kidney Sarcoma

Expression for Kidney Sarcoma

Search GEO for disease gene expression data for Kidney Sarcoma.

Pathways for Kidney Sarcoma

Pathways related to Kidney Sarcoma according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.21 WT1 SSX2 SSX1 SS18
2
Show member pathways
10.81 YWHAE CCNB3
3 10.23 YWHAE CCNB3

GO Terms for Kidney Sarcoma

Cellular components related to Kidney Sarcoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleus GO:0005634 9.36 YWHAE WT1 VGLL2 TLE1 SWT1 SSX2

Sources for Kidney Sarcoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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