Klebsiella Pneumonia disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

MCID: KLB003 MIFTS: 35	Klebsiella Pneumonia Categories: Infectious diseases, Respiratory diseases	Data Licensing For inquiries, contact: [email protected]
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Aliases & Classifications for Klebsiella Pneumonia

MalaCards integrated aliases for Klebsiella Pneumonia:

Name: Klebsiella Pneumonia ¹¹ ⁵³

Pneumonia Due to Klebsiella Pneumoniae ¹¹ ³¹ ³³

Klebsiella Infections ⁴³ ¹⁶

Klebsiella Lobar Pneumonia ³³

Doid:13272 ¹⁴

Classifications:

MalaCards categories:
Global: Infectious diseases
Anatomical: Respiratory diseases

See all MalaCards categories (disease lists)

ICD10: ³¹

Certain infectious and parasitic diseases

Bacterial, viral and other infectious agents

Other specified bacterial agents as the cause of diseases classified to other chapters

Klebsiella pneumoniae [K. pneumoniae] as the cause of diseases classified to other chapters

Diseases of the respiratory system

Influenza and pneumonia

Bacterial pneumonia, not elsewhere classified

Pneumonia due to Klebsiella pneumoniae

ICD11: ³³

Diseases of the respiratory system

Lung infections

Pneumonia

Bacterial pneumonia

Pneumonia due to Klebsiella pneumoniae

External Ids:

Disease Ontology ¹¹ DOID:13272

ICD9CM ³⁴ 482.0

MeSH ⁴³ D007710

ICD10 ³¹ B96.1 J15.0

EFO ¹⁶ EFO_1001353

ICD11 ³³ 1250089989

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Summaries for Klebsiella Pneumonia

Disease Ontology: ¹¹ A bacterial pneumonia involving Klebsiella pneumoniae infection. Patients with Klebsiella pneumonia tend to cough up a characteristic sputum that is said to resemble red-currant jelly. Klebsiella pneumonia tends to affect people with underlying diseases, such as alcoholism, diabetes and chronic lung disease. The symptoms include high fever, rigors and pleuritic pain, and hemoptysis.

MalaCards based summary: Klebsiella Pneumonia, also known as pneumonia due to klebsiella pneumoniae, is related to bacteremia 2 and pneumonia. An important gene associated with Klebsiella Pneumonia is LACTB (Lactamase Beta), and among its related pathways/superpathways is Complement cascade. The drugs Tazobactam and Piperacillin have been mentioned in the context of this disorder. Affiliated tissues include lung, liver and kidney.

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Related Diseases for Klebsiella Pneumonia

Diseases related to Klebsiella Pneumonia via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 459)

#	Related Disease	Score	Top Affiliating Genes
1	bacteremia 2	30.7	LACTB CRP
2	pneumonia	30.5	LACTB GPT CRP ALB
3	endophthalmitis	30.3	CRP ALB
4	meningitis	30.1	LACTB CRP ALB
5	bacterial pneumonia	29.8	LACTB GPT CRP ALB
6	dysentery	29.7	CRP ALB
7	lung abscess	29.7	LACTB GPT CRP ALB
8	polyarteritis nodosa	29.5	GPT CRP
9	epidural abscess	29.5	F3 CRP ALB
10	necrotizing fasciitis	29.5	F3 CRP ALB
11	pleural empyema	29.5	GPT CRP ALB
12	thrombophlebitis	29.5	F3 CRP ALB
13	bacterial sepsis	29.5	F3 CRP ALB
14	bronchopneumonia	29.5	GPT CRP ALB
15	thrombocytosis	29.5	F3 CRP ALB
16	alcohol use disorder	29.5	GPT CRP ALB
17	pulmonary embolism	29.5	F3 CRP ALB
18	urinary tract infection	29.4	GPT F3 CRP ALB
19	critical covid-19	29.3	GPT F3 CRP
20	respiratory failure	29.3	GPT F3 CRP ALB
21	pyelonephritis	29.2	GPT CRP ALB
22	septic arthritis	29.2	GPT CRP ALB
23	alcoholic hepatitis	29.2	GPT CRP ALB
24	pancytopenia	29.2	GPT CRP ALB
25	severe covid-19	28.9	GPT F3 CRP ALB
26	cellulitis	28.6	LACTB GPT F3 CRP ALB
27	klebsiella infection	11.0
28	suppressor of tumorigenicity 11	10.2
29	48,xyyy	10.2
30	aspergillosis	10.2
31	intracranial abscess	10.2	LACTB CRP
32	third-degree atrioventricular block	10.2
33	lactic acidosis	10.2
34	epiglottitis	10.2	LACTB CRP
35	maxillary sinusitis	10.1	LACTB CRP
36	achenbach syndrome	10.1	F3 CRP
37	synovial angioma	10.1	F3 CRP
38	femoral neuropathy	10.1	F3 CRP
39	blue toe syndrome	10.1	F3 CRP
40	renal pelvis squamous cell carcinoma	10.1	F3 CRP
41	subclavian steal syndrome	10.1	F3 CRP
42	waterhouse-friderichsen syndrome	10.1	F3 CRP
43	cavernous sinus thrombosis	10.1	F3 CRP
44	nonbacterial thrombotic endocarditis	10.1	F3 CRP
45	pericoronitis	10.1	F3 CRP
46	lemierre's syndrome	10.1	F3 CRP
47	branch retinal artery occlusion	10.1	F3 CRP
48	hemopericardium	10.1	F3 CRP
49	acute cor pulmonale	10.1	F3 CRP
50	acute pulmonary heart disease	10.1	F3 CRP

Graphical network of the top 20 diseases related to Klebsiella Pneumonia:

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Symptoms & Phenotypes for Klebsiella Pneumonia

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Drugs & Therapeutics for Klebsiella Pneumonia

Drugs for Klebsiella Pneumonia (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 37)

Name

Status

Phase

Clinical Trials

Cas Number

PubChem Id

Tazobactam

Approved

Phase 4

89786-04-9

123630

Piperacillin

Approved

Phase 4

66258-76-2

43672

Meropenem

Approved, Investigational

Phase 4

119478-56-7, 96036-03-2

441130

Polymyxin B

Approved, Vet_approved

Phase 4

1405-20-5, 1404-26-8

4868

Colistin

Approved

Phase 4

1264-72-8, 1066-17-7

5311054

Tigecycline

Approved

Phase 4

220620-09-7

5282044

Ertapenem

Approved, Investigational

Phase 4

153832-46-3

150610

Ciprofloxacin

Approved, Investigational

Phase 4

85721-33-1, 93107-08-5

2764

Ceftriaxone

Approved

Phase 4

73384-59-5

5479530

Levoleucovorin

Approved, Experimental, Investigational

Phase 4

68538-85-2, 58-05-9, 73951-54-9

149436 6006

Trimethoprim

Approved, Vet_approved

Phase 4

738-70-5

5578

Sulfamethoxazole

Approved

Phase 4

723-46-6

5329

Folic acid

Approved, Nutraceutical, Vet_approved

Phase 4

59-30-3

6037

beta-Lactamase Inhibitors

Phase 4

Piperacillin, Tazobactam Drug Combination

Phase 4

Pharmaceutical Solutions

Phase 4

Polymyxins

Phase 4

Gentamicins

Phase 4

Anti-Bacterial Agents

Phase 4

Anti-Infective Agents

Phase 4

Antibiotics, Antitubercular

Phase 4

Folic Acid Antagonists

Phase 4

Folate

Phase 4

Liver Extracts

Phase 4

Vitamin B9

Phase 4

Antiprotozoal Agents

Phase 4

Antiparasitic Agents

Phase 4

Vitamin B Complex

Phase 4

Antimalarials

Phase 4

Trimethoprim, Sulfamethoxazole Drug Combination

Phase 4

Cytochrome P-450 Enzyme Inhibitors

Phase 4

Sitafloxacin

Experimental, Investigational

Phase 2, Phase 3

163253-35-8

Vaccines

Phase 1, Phase 2

Imipenem

Approved

74431-23-5, 64221-86-9

104838

Vancomycin

Approved

1404-90-6

14969

Framycetin

Approved, Experimental, Vet_approved

1404-04-2, 119-04-0, 3947-65-7

413349 8378

Streptomycin

Approved, Vet_approved

57-92-1

19649

Interventional clinical trials:

(show all 27)

#	Name	Status	NCT ID	Phase	Drugs
1	Piperacillin/Tazobactam Versus Carbapenems in Non-bacteremic Urinary Tract Infections Due to Extended-spectrum β-lactamase (ESBL)-Producing Escherichia Coli or Klebsiella Pneumoniae - (CAPITIS Study)	Unknown status	NCT03891433	Phase 4	Meropenem;Ertapenem 1000 MG;Piperacillin, Tazobactam 4-0.5G Solution for Injection
2	Comparative Clinical Study Between Colistin-Tigecycline Combined Therapy Versus Colistin-Meropenem Combined Therapy in Treatment of Blood Stream Infections With Multidrug-Resistant Klebsiella Pneumoniae	Unknown status	NCT04489459	Phase 4	Colistin;Meropenem;Tigecycline
3	SELECTIVE DIGESTIVE DECONTAMINATION USING ORAL GENTAMICIN AND ORAL POLYMYXIN E FOR ERADICATION OF CARBAPENEM-RESISTANT KLEBSIELLA PNEUMONIAE CARRIAGE IN HOSPITALIZED PATIENTS	Unknown status	NCT01761487	Phase 4
4	A Multi-centre Randomised Open-label Active Comparator-controlled Non-inferiority Trial Comparing Oral to Intravenous Antibiotics in the Early Management of Klebsiella Pneumoniae Liver Abscess	Completed	NCT01723150	Phase 4	Ciprofloxacin;Ceftriaxone;Trimethoprim/sulfamethoxazole;Ertapenem
5	Sitafloxacin and Ertapenem Treatment for Acute Urinary Tract Infection Caused by E. Coli or K. Pneumoniae in Post-kidney Transplantation Patients	Recruiting	NCT02729116	Phase 2, Phase 3	Sitafloxacin;Ertapenem
6	Safety and Efficacy Study of Eradication of Carbapenem Resistant Klebsiella Pneumonia From the Gastrointestinal Tract by Probiotics.	Unknown status	NCT00722410	Phase 1, Phase 2	Polyethylene glycol
7	Safety and Immunogenicity of a Klebsiella Pneumoniae Tetravalent Bioconjugate Vaccine (Kleb4V) Administered to Healthy Adults: A FTIH Phase I/II Randomized and Controlled Study	Completed	NCT04959344	Phase 1, Phase 2
8	Randomized, Superiority, Double Blind Controlled With Placebo, Clinical Trial, to Demonstrate the Effectiveness of Fecal Microbiota Transplantation for Selective Intestinal Decolonization of Patients Colonized by Klebsiella Pneumoniae Carbapenemase (KPC)-Producing	Recruiting	NCT04760665	Phase 2
9	Analysis on the Infection Risk, Prognosis, and Drug Sensitivity of Klebsiella Pneumoniae.	Unknown status	NCT04337840
10	Comparison of Clinical Outcomes in Bloodstream Infections With Carbapenem Hetero-resistant vs Carbapenem Resistant Klebsiella Pneumoniae (COMBAT)	Unknown status	NCT04229498		Monotherapy and combination therapy (all antibiotics that are given by attending pysicians and can be active against Klebsiella pneumoniae will be evaluated)
11	Klebsiella Pneumoniae Infection in China: Epidemiology, Molecular Characteristics, Treatment, and Outcome	Unknown status	NCT03598543
12	WGS-guided Tracking and Infection Control Measures of Carbapenem-resistant Klebsiella Pneumoniae	Unknown status	NCT04413305
13	Epidemiological Characteristics and Treatment Protocol for Carbapenem-Resistant Klebsiella Pneumoniae in China	Unknown status	NCT03245632
14	Effects of Piperacillin-Tazobactam Use on the Prevalence Rate of Extended-Spectrum Beta-Lactamase (ESBL) Producing Escherichia Coli and Klebsiella Pneumoniae in Hematology and Oncology Units.	Completed	NCT00167999		piperacillin-tazobactam
15	Antibiotic Intervention Trial in a Medical Intensive Care Unit to Reduce the Acquisition of Vancomycin-Resistant Enterococci and ESBL Producing Escherichia Coli and Klebsiella Pneumoniae.	Completed	NCT00167986		vancomycin-resistant enterococci and ESBL
16	Community - Associated Extended-spectrum Beta-lactamases (ESBL)	Completed	NCT00363220
17	Efficacy of Intestinal Decontamination in Patients Colonized by Carbapenem-resistant Klebsiella Pneumoniae and Colistin	Completed	NCT02604849		Neomycin;Streptomycin;Gentamicins
18	Risk Factors for Quinolone Resistance Among Extended-Spectrum Beta-Lactamase-Producing Klebsiella Species	Completed	NCT00518661
19	Double Carbapenem as Rescue Strategy for the Treatment of Severe Carbapenemase-Producing Klebsiella Pneumoniae Infections: A Two-Center Matched Case-Control Study	Completed	NCT03094494
20	Turkish Prospective Cohort Study on Carbapenem Resistant Klebsiella Pneumonia Bacteremia: a National Multicenter Observational Study	Completed	NCT03597841		Combination therapy
21	Klebsiella Pneumoniae Necrotizing Fasciitis: Clinical and Microbiological Features	Completed	NCT01139112
22	A Randomized Open Label Study Evaluating the Role of Oral Antibiotics in an Aim to Eradicate Carrier State of Carbapenem- Resistant Klebsiella Pneumonia (KPC).	Completed	NCT01266499		Colistin (Polymyxin E) 100mg x 4/d;both medications;will not receive PO treatment;PO Garamycin 80mg x 4/d
23	Sites of Colonization in Hospitalized Patients With Infections Caused by Extended-Spectrum Beta-Lactamase Producing Escherichia Coli and Klebsiella Pneumoniae	Completed	NCT01324726
24	Antimicrobial Resistance Rate In Escherichia Coli And Klebsiella Pneumonia : A Retrospective Study	Completed	NCT04196387
25	The Incidence of Extended-spectrum β-lactamase (ESBL) Klebsiella Pneumonia in Patient on Renal Replacement Therapy	Completed	NCT01612182
26	Type VI Secretion System in Klebsiella Pneumoniae Relation to Antibiotic Resistance and Biofilm Formation	Recruiting	NCT05516654
27	Prognosis of Klebsiella ESBL Sepsis: Role of 2-HYDRoxy-myristate in Endotoxin Structure	Active, not recruiting	NCT05193045

Search NIH Clinical Center for Klebsiella Pneumonia

Cochrane evidence based reviews: klebsiella infections

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Genetic Tests for Klebsiella Pneumonia

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Anatomical Context for Klebsiella Pneumonia

Organs/tissues related to Klebsiella Pneumonia:

MalaCards : Lung, Liver, Kidney, Whole Blood, Bone Marrow, Spinal Cord, Neutrophil

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Publications for Klebsiella Pneumonia

Articles related to Klebsiella Pneumonia:

(show top 50) (show all 1577)

#	Title	Authors	PMID	Year
1	Nosocomial bloodstream infections in a pediatric intensive care unit: 3-year survey. ⁵³ ⁶²	Grisaru-Soen G...Paret G	17534230	2007
2	Antibiotic therapy for Klebsiella pneumoniae bacteremia: implications of production of extended-spectrum beta-lactamases. ⁵³ ⁶²	Paterson DL...Yu VL	15206050	2004
3	FeoC from Klebsiella pneumoniae uses its iron sulfur cluster to regulate the GTPase activity of the ferrous iron channel. ⁶²	Hsueh KL...Chen CJ	36182071	2023
4	Anti-microbial and cytotoxic activity of ZzAMP, a serine protease inhibitor (SPI) with nutraceutical potential from rhizomes of medicinal plant, Zingiber zerumbet. ⁶²	Raj S...Nair RA	35105207	2022
5	Chemical compositions, antibacterial, antifungal and cytotoxic effects of Alhagi mannifera five extracts. ⁶²	Jaradat N...Arar M	34384010	2022
6	Reconstructing ethanol oxidation pathway in Pseudomonas putida KT2440 for bio-upgrading of ethanol to biodegradable polyhydroxybutanoates. ⁶²	Nguyen LT...Lee EY	36174870	2022
7	Sequencing analysis of tigecycline resistance among tigecycline non-susceptible in three species of G-ve bacteria isolated from clinical specimens in Baghdad. ⁶²	Khlaif MM...Hussein NH	36207501	2022
8	Molecular docking studies and biological evaluation of isoxazole-carboxamide derivatives as COX inhibitors and antimicrobial agents. ⁶²	Hawash M...Arar M	36345437	2022
9	Biogenic synthesis of ZnO nanoparticles mediated from Borassus flabellifer (Linn): antioxidant, antimicrobial activity against clinical pathogens, and photocatalytic degradation activity with molecular modeling. ⁶²	Kalaimurugan D...Venkatesan S	35040048	2022
10	MCR-1-dependent lipid remodelling compromises the viability of Gram-negative bacteria. ⁶²	Feng S...Tian GB	35437117	2022
11	Associated microbiota and treatment of severe fever with thrombocytopenia syndrome complicated with infections. ⁶²	Zhang Y...Xu Y	35945160	2022
12	Exploiting the Acidic Extracellular pH: Evaluation of Streptococcus salivarius M18 Postbiotics to Target Cancer Cells. ⁶²	Karacam S...Tuncer S	34080175	2022
13	Chemical Profiling and In Vitro Antiurolithiatic Activity of Pleurolobus gangeticus (L.) J. St.- Hil. ex H. Ohashi & K. Ohashi Along with Its Antioxidant and Antibacterial Properties. ⁶²	Mohan PK...Kumari BDR	35687306	2022
14	Comparative Study of Antimicrobial Activity of Silver, Gold, and Silver/Gold Bimetallic Nanoparticles Synthesized by Green Approach. ⁶²	Sher N...Aboul-Soud MAM	36431998	2022
15	In-silico functional and structural annotation of hypothetical protein from Klebsiella pneumonia: A potential drug target. ⁶²	Singh V...Kumar P	35839717	2022
16	A novel family of non-secreted tridecaptin lipopeptide produced by Paenibacillus elgii. ⁶²	da Costa RA...Barreto CC	35864259	2022
17	Multidrug resistant bacterial infections in severely ill COVID-19 patients admitted in a national referral and teaching hospital, Kenya. ⁶²	Mutua JM...Musyoki AM	36418990	2022
18	Identification and Antimicrobial Resistance in Klebsiella spp. Isolates from Turkeys in Poland between 2019 and 2022. ⁶²	Kowalczyk J...Koncicki A	36428385	2022
19	Antibacterial studies of [email protected]@GO nanocomposites and their effects on fouling and dye rejection in PES UF membranes. ⁶²	Chukwuati CN...Moutloali RM	36468096	2022
20	Antimicrobial Applications of Green Synthesized Bimetallic Nanoparticles from Ocimum basilicum. ⁶²	More PR...Galdiero M	36432648	2022
21	Efficacy predictors of third-generation cephalosporins in treating spontaneous bacterial peritonitis. ⁶²	Zhu LC...Xiong ML	36221348	2022
22	8-Amino-7-(aryl/hetaryl)fluoroquinolones. An emerging set of synthetic antibacterial agents. ⁶²	Al-Akhras AA...Khanfar MA	36278497	2022
23	Studies on antimicrobial stress with reference to biofilm formation of faecal microbial communities from Apatani tribe of Arunachal Pradesh. ⁶²	Hazarika P...Sharma I	36244849	2022
24	A cross-sectional study on clinical, demographic, microbiological, and radiological profile of bronchiectasis patients attending a tertiary care teaching center. ⁶²	Ramya VH...Sidharthan VH	36460391	2022
25	Rapid Bacterial Identification and Drug Sensitivity Test Methods for Pathogens in Positive Blood Cultures. ⁶²	Zhou YZ...Li CB	36250829	2022
26	Oral microbiota associated with gingiva of healthy, gingivitis and periodontitis cases. ⁶²	Hussein NA...Edrees MF	35988883	2022
27	Neonatal Healthcare-Associated Conjunctivitis: A Descriptive Study from Saudi Arabia. ⁶²	Alhazmi A...Shami J	36295608	2022
28	Maternal colonization and early-onset neonatal bacterial sepsis in the Gambia, West Africa: a genomic analysis of vertical transmission. ⁶²	Okomo UA...Kampmann B	36243352	2022
29	INTRAPULMONARY TREATMENT WITH A NOVEL TLR4 AGONIST CONFERS PROTECTION AGAINST KLEBSIELLA PNEUMONIA. ⁶²	Hernandez A...Sherwood ER	36018281	2022
30	A review: Virulence factors of Klebsiella pneumonia as emerging infection on the food chain. ⁶²	Riwu KHP...Widodo A	36341059	2022
31	Preparation and evaluation of a new combined conjugated vaccine against Klebsiella pneumonia and Pseudomonas aeruginosa. ⁶²	Bahy R...El-Gebaly EAEA	35652238	2022
32	A Rare but Life-Threatening Case of Fournier's Gangrene Caused by Sodium-Glucose Cotransporter-2 (SGLT2) Inhibitor, Empagliflozin. ⁶²	Jahir T...Schmidt M	36262942	2022
33	Xanthogranulomatous inflammation caused by K. pneumonia and nocardiosis mimicking a uterine tumor and invading the ureter and colon: A case report and review of the literature. ⁶²	Shen TA...Ding DC	36088063	2022
34	Evaluation of Green Silver Nanoparticles Fabricated by Spirulina platensis Phycocyanin as Anticancer and Antimicrobial Agents. ⁶²	Soror AS...Abdalla H	36294927	2022
35	Community-acquired pneumonia-causing bacteria and antibiotic resistance rate among Vietnamese patients: A cross-sectional study. ⁶²	Tran HD...Tran HG	36086715	2022
36	Effect of Cu Modified Textile Structures on Antibacterial and Antiviral Protection. ⁶²	Cieslak M...Kaminska I	36079542	2022
37	Trends of Bloodstream Infections in a University Hospital During 12 Years. ⁶²	Ulku Tuzemen N...Akalin H	36185018	2022
38	Urgent nephrectomy for rapidly progressive disseminated metastatic Hypermucoid Klebsiella. ⁶²	Neerhut T...Rhee H	35846515	2022
39	Silver Nanoparticles Conjugated with Colistin Enhanced the Antimicrobial Activity against Gram-Negative Bacteria. ⁶²	Muenraya P...Atipairin A	36144516	2022
40	Biomimetic facile synthesis of zinc oxide and copper oxide nanoparticles from Elaeagnus indica for enhanced photocatalytic activity. ⁶²	Indhira D...Kumar GS	35472463	2022
41	Antibiotic Resistance during COVID-19: A Systematic Review. ⁶²	Sulayyim HJA...Ghafar NA	36231256	2022
42	Promising Endophytic Alternaria alternata from Leaves of Ziziphus spina-christi: Phytochemical Analyses, Antimicrobial and Antioxidant Activities. ⁶²	Elghaffar RYA...Sehim AE	35579741	2022
43	Demographics, Radiological Findings, and Clinical Outcomes of Klebsiella pneumonia vs. Non-Klebsiella pneumoniae Pyogenic Liver Abscess: A Systematic Review and Meta-Analysis with Trial Sequential Analysis. ⁶²	Chan KS...Shelat VG	36145408	2022
44	Metagenomics-based antibiotic resistance genes diversity and prevalence risk revealed by pathogenic bacterial host in Taihu Lake, China. ⁶²	Bai Y...Wang Z	34292452	2022
45	Green synthesis of silver nanoparticles from plant latex and their antibacterial and photocatalytic studies. ⁶²	Chandhru M...Vasimalai N	33825663	2022
46	Prevalence, Antibiogram, and Associated Factors of Bacteria Isolated From Presumptive Meningitis Patients at Debre Markos Comprehensive Specialized Hospital, Northwest Ethiopia. ⁶²	Hibstu Z...Mengist HM	36185882	2022
47	Deep Sternal Wound Infection After Open-heart Cardiac Surgery and Vacuum-Assisted Closure Therapy: a Single-center Study. ⁶²	Banjanovic B...Granov N	36313952	2022
48	In-vitro determination of antimicrobial activities of Eruca sativa seed oil against antibiotic-resistant gram-negative clinical isolates from neonates: a future prospect. ⁶²	Bassyouni RH...Gaber SN	36030221	2022
49	GC-MS and in vitro antibacterial potential of Cinnamomum camphora essential oil against some clinical antibiotic-resistant bacterial isolates. ⁶²	Mujawah AAH...Alhumaydhi FA	35993631	2022
50	Design, Synthesis and Mechanistic Studies of Novel Isatin-Pyrazole Hydrazone Conjugates as Selective and Potent Bacterial MetAP Inhibitors. ⁶²	Irfan I...Abid M	36009995	2022

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Genes for Klebsiella Pneumonia

Genes related to Klebsiella Pneumonia (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence	PubMed IDs
1	LACTB	Lactamase Beta	Protein Coding	5.34	Novoseek inferred ⁵³	15206050 17534230
2	MASP1	MBL Associated Serine Protease 1	Protein Coding	4.6	DISEASES inferred ¹⁴
3	OGA	O-GlcNAcase	Protein Coding	3.94	DISEASES inferred ¹⁴
4	CRP	C-Reactive Protein	Protein Coding	3.73	DISEASES inferred ¹⁴
5	ALB	Albumin	Protein Coding	3.65	DISEASES inferred ¹⁴
6	GPT	Glutamic--Pyruvic Transaminase	Protein Coding	3.35	DISEASES inferred ¹⁴
7	F3	Coagulation Factor III, Tissue Factor	Protein Coding	2.85	DISEASES inferred ¹⁴

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Variations for Klebsiella Pneumonia

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Expression for Klebsiella Pneumonia

Search GEO for disease gene expression data for Klebsiella Pneumonia.

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Pathways for Klebsiella Pneumonia

Pathways related to Klebsiella Pneumonia according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Complement cascade ⁶⁶ Show member pathways Activation of C3 and C5 ⁶⁶ Classical Complement Pathway ⁶⁴ Complement Pathway ⁶⁴ Complement system ⁷⁴ Complement system in neuronal development and plasticity ⁷⁴ Lectin Induced Complement Pathway ⁶⁴ Regulation of Complement cascade ⁶⁶	11.36	MASP1 CRP ALB