Aliases & Classifications for Kleptomania

MalaCards integrated aliases for Kleptomania:

Name: Kleptomania 12 15 73
Pathological Stealing 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12400
ICD10 33 F63.2
ICD9CM 35 312.32
MeSH 44 D007174
NCIt 50 C94333
SNOMED-CT 68 69361009
UMLS 73 C0022734

Summaries for Kleptomania

Disease Ontology : 12 An impulse control disorder that involves the repeated impulse to steal for no great gain, when he or she has sufficient money to pay for the item and no need for what is stolen.

MalaCards based summary : Kleptomania, also known as pathological stealing, is related to depression and pathological gambling. An important gene associated with Kleptomania is ABCB6 (ATP Binding Cassette Subfamily B Member 6 (Langereis Blood Group)), and among its related pathways/superpathways are Drug metabolism - cytochrome P450 and superpathway of tryptophan utilization. The drugs Carbidopa and Levodopa have been mentioned in the context of this disorder. Affiliated tissues include testes, and related phenotype is homeostasis/metabolism.

Wikipedia : 76 Kleptomania or klopemania is the inability to refrain from the urge for stealing items and is usually... more...

Related Diseases for Kleptomania

Diseases related to Kleptomania via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 66)
# Related Disease Score Top Affiliating Genes
1 depression 30.3 HTR1A MAOA SLC6A4
2 pathological gambling 30.3 MAOA SLC6A4
3 exhibitionism 30.2 ABCB6 MAOA
4 personality disorder 30.2 HTR1A MAOA SLC6A4
5 obsessive-compulsive disorder 30.1 HTR1A MAOA SLC6A4 SLITRK1
6 mood disorder 29.9 HTR1A MAOA SLC6A4
7 schizophrenia 29.5 CYP1A2 HTR1A HTR7 MAOA SLC6A4
8 major depressive disorder 29.4 CYP2C19 GATA3 HTR1A MAOA SLC6A4
9 pyromania 11.1
10 stereotypic movement disorder 10.2 ABCB6 SLITRK1
11 trichotillomania 10.2 ABCB6 SLITRK1
12 rumination disorder 10.2 HTR1A HTR7
13 motion sickness 10.2 HTR1A HTR7
14 drug-induced mental disorder 10.2 HTR1A HTR7
15 drug psychosis 10.2 HTR1A HTR7
16 paraphilia disorder 10.1 ABCB6 MAOA
17 sexual disorder 10.1 HTR1A SLC6A4
18 avoidant personality disorder 10.1 MAOA SLC6A4
19 attention deficit-hyperactivity disorder 10.1
20 periodic limb movement disorder 10.1 HTR1A SLC6A4
21 premature ejaculation 10.1 HTR1A SLC6A4
22 amnestic disorder 10.1 HTR1A HTR7
23 alexithymia 10.1 HTR1A SLC6A4
24 oppositional defiant disorder 10.1 MAOA SLC6A4
25 neurotic excoriation 10.0 HTR7 PPIG SLITRK1
26 psychosexual disorder 10.0 HTR1A HTR7 SLC6A4
27 intermittent explosive disorder 10.0 HTR1A HTR7 SLC6A4
28 antisocial personality disorder 10.0 MAOA SLC6A4
29 atypical depressive disorder 10.0 HTR7 MAOA SLC6A4
30 phobic disorder 10.0 HTR1A MAOA SLC6A4
31 paranoid schizophrenia 10.0 MAOA SLC6A4
32 social phobia 10.0 HTR1A MAOA SLC6A4
33 agoraphobia 10.0 HTR1A MAOA SLC6A4
34 borderline personality disorder 10.0 HTR1A MAOA SLC6A4
35 generalized anxiety disorder 10.0 HTR1A MAOA SLC6A4
36 chronic fatigue syndrome 10.0 HTR1A MAOA SLC6A4
37 dopamine beta-hydroxylase deficiency, congenital 10.0 GATA3 MAOA
38 dyspepsia 10.0 CYP2C19 HTR1A SLC6A4
39 panic disorder 10.0 HTR1A MAOA SLC6A4
40 esophageal candidiasis 10.0 CYP2C19 CYP3A4
41 dependent personality disorder 10.0 CYP3A4 MAOA
42 postpartum depression 10.0 MAOA SLC6A4
43 sudden infant death syndrome 10.0 HTR1A MAOA SLC6A4
44 bulimia nervosa 10.0
45 fetishism 10.0
46 epilepsy 10.0
47 eating disorder 10.0
48 migraine without aura 9.9 HTR1A SLC6A4
49 alcohol dependence 9.9 HTR1A MAOA SLC6A4
50 brunner syndrome 9.9 HTR1A HTR7 MAOA SLC6A4

Graphical network of the top 20 diseases related to Kleptomania:



Diseases related to Kleptomania

Symptoms & Phenotypes for Kleptomania

MGI Mouse Phenotypes related to Kleptomania:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.28 ABCB6 CYP1A2 GATA3 HTR1A HTR7 MAOA

Drugs & Therapeutics for Kleptomania

Drugs for Kleptomania (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carbidopa Approved Phase 3 28860-95-9 34359 38101
2
Levodopa Approved Phase 3 59-92-7 6047
3
Dopamine Approved Phase 3,Phase 2 51-61-6, 62-31-7 681
4 Immunologic Factors Phase 3
5 Adjuvants, Immunologic Phase 3
6 Dopamine agonists Phase 3
7 Antiparkinson Agents Phase 3,Phase 2
8 Dopamine Agents Phase 3,Phase 2
9 Aromatic Amino Acid Decarboxylase Inhibitors Phase 3
10 Carbidopa, levodopa drug combination Phase 3
11 Neurotransmitter Agents Phase 3,Phase 2
12
Naltrexone Approved, Investigational, Vet_approved Phase 2 16590-41-3 5360515
13
Memantine Approved, Investigational Phase 2 19982-08-2 4054
14 Narcotic Antagonists Phase 2
15 Peripheral Nervous System Agents Phase 2
16 Narcotics Phase 2
17 Excitatory Amino Acid Antagonists Phase 2
18 Excitatory Amino Acids Phase 2
19
Ethanol Approved Not Applicable 64-17-5 702
20 Central Nervous System Depressants Not Applicable
21 Anti-Infective Agents, Local Not Applicable
22 Anti-Infective Agents Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety/Efficacy Study of Levodopa-Carbidopa Intestinal Gel in Parkinson's Subjects Completed NCT00360568 Phase 3 Levodopa-carbidopa intestinal gel
2 Levodopa-Carbidopa Intestinal Gel Open-Label Study in Advanced Parkinson's Disease Completed NCT00335153 Phase 3 Levodopa-carbidopa intestinal gel
3 Double-Blind Naltrexone in Kleptomania Completed NCT00332579 Phase 2 Naltrexone;Placebo
4 Memantine in the Treatment of Kleptomania Completed NCT00880685 Phase 2 Memantine
5 Alcohol Related Impairment and Reinforcement: Pre to Post Roux en Y Gastric Bypass Surgery Recruiting NCT02370732 Not Applicable

Search NIH Clinical Center for Kleptomania

Genetic Tests for Kleptomania

Anatomical Context for Kleptomania

MalaCards organs/tissues related to Kleptomania:

41
Testes

Publications for Kleptomania

Articles related to Kleptomania:

(show top 50) (show all 98)
# Title Authors Year
1
Symptom severity and its clinical correlates in kleptomania. ( 29697710 )
2018
2
Stealing behavior and impulsivity in individuals with kleptomania who have been arrested for shoplifting. ( 29127886 )
2018
3
Kleptomania or common theft - diagnostic and judicial difficulties. ( 29704416 )
2018
4
Aripiprazole-induced kleptomania: Case report. ( 29884322 )
2018
5
Imaging studies of kleptomania in a middle-aged woman with obsessive-compulsive disorder: a case report. ( 29987861 )
2018
6
Kleptomania: Recent Advances in Symptoms, Etiology and Treatment. ( 30341533 )
2018
7
Impairments of kleptomania: what are they? ( 28813121 )
2017
8
Kleptomania and Co-morbid addictive disorders. ( 28142063 )
2017
9
A case of venlafaxine-induced kleptomania. ( 26706250 )
2016
10
Kleptomania following hypoxic-ischaemic damage to bilateral caudate nuclei. ( 26825938 )
2016
11
Self-Limited Kleptomania Symptoms as a Side Effect of Duloxetine. ( 28018697 )
2016
12
Cross-cultural comparison of compulsive stealing (kleptomania). ( 25696786 )
2015
13
Kleptomania: a case series. ( 25630329 )
2014
14
Kleptomania: Beyond serotonin. ( 25540525 )
2014
15
Treating kleptomania: cross-cultural adaptation of the Kleptomania Symptom Assessment Scale and assessment of an outpatient program. ( 25306380 )
2014
16
Emergence of kleptomania during treatment for obsessive compulsive disorder with fluvoxamine. ( 24574573 )
2014
17
The possible effect of methylphenidate on kleptomania in a school-age girl with attention-deficit/hyperactivity disorder. ( 24122344 )
2013
18
Kleptomania in patients with neuro-BehAset's disease. ( 23920112 )
2013
19
Memantine reduces stealing behavior and impulsivity in kleptomania: a pilot study. ( 23299454 )
2013
20
Quetiapine-associated pathological stealing in an adolescent girl. ( 23487235 )
2013
21
Naltrexone treatment of kleptomania: a case report. ( 23225130 )
2012
22
Suicide attempts in 107 adolescents and adults with kleptomania. ( 23137224 )
2012
23
An adolescent with kleptomania and attention-deficit/hyperactivity disorder treated with methylphenidate. ( 21823916 )
2011
24
Kleptomania treated with tolcapone, a catechol-O-methyl-transferase (COMT) inhibitor. ( 21062636 )
2011
25
Kleptomania and potential exacerbating factors: a review and case report. ( 22132369 )
2011
26
Pathological stealing in dementia: poor response to SSRI medications. ( 21450164 )
2011
27
Pathological stealing in a patient with systemic lupus erythematosus: rare or hidden? ( 21546413 )
2011
28
Kleptomania, an unusual impulsive control disorder in Parkinson's disease? ( 20202886 )
2010
29
Kleptomania: clinical characteristics and relationship to substance use disorders. ( 20575650 )
2010
30
Legal consequences of kleptomania. ( 19813092 )
2009
31
A double-blind, placebo-controlled study of the opiate antagonist, naltrexone, in the treatment of kleptomania. ( 19217077 )
2009
32
Gender-related differences in individuals seeking treatment for kleptomania. ( 18323758 )
2008
33
Neuropsychological functioning in kleptomania. ( 17007811 )
2007
34
Epilepsy and kleptomania. ( 17905665 )
2007
35
Escitalopram treatment of kleptomania: an open-label trial followed by double-blind discontinuation. ( 17388713 )
2007
36
A Structured Clinical Interview for Kleptomania (SCI-K): preliminary validity and reliability testing. ( 19722289 )
2006
37
Understanding and treating kleptomania: new models and new treatments. ( 16910369 )
2006
38
White matter integrity in kleptomania: a pilot study. ( 16956753 )
2006
39
Quality of life in kleptomania and pathological gambling. ( 15714192 )
2005
40
Outcome study of kleptomania patients treated with naltrexone: a chart review. ( 15711433 )
2005
41
Re: Co-occurrence of personality disorders in persons with kleptomania: a preliminary investigation. ( 16186216 )
2005
42
Co-occurrence of personality disorders in persons with kleptomania: a preliminary investigation. ( 15704625 )
2004
43
A case of kleptomania correlating with premenstrual dysphoria. ( 15163267 )
2004
44
Comorbid psychiatric diagnoses in kleptomania and pathological gambling: a preliminary comparison study. ( 15276663 )
2004
45
Kleptomania after head trauma: two case reports and combination treatment strategies. ( 15602100 )
2004
46
Dissociative symptoms in kleptomania. ( 15077751 )
2004
47
Kleptomania: comorbid psychiatric diagnosis in patients and their families. ( 15057031 )
2004
48
Overview of Kleptomania and Phenomenological Description of 40 Patients. ( 15614312 )
2004
49
Family history and psychiatric comorbidity in persons with kleptomania. ( 14610719 )
2003
50
Topiramate for the treatment of kleptomania: a case series and review of the literature. ( 12567156 )
2003

Variations for Kleptomania

Expression for Kleptomania

Search GEO for disease gene expression data for Kleptomania.

Pathways for Kleptomania

Pathways related to Kleptomania according to GeneCards Suite gene sharing:

(show all 23)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.56 CYP1A2 CYP2C19 CYP3A4 MAOA TYMP
2
Show member pathways
11.95 CYP1A2 CYP2C19 CYP3A4 MAOA
3 11.88 GATA3 HTR1A MAOA SLC6A4
4
Show member pathways
11.77 CYP1A2 CYP2C19 CYP3A4
5
Show member pathways
11.57 CYP1A2 CYP2C19 CYP3A4
6
Show member pathways
11.48 CYP1A2 CYP2C19 CYP3A4
7 11.41 CYP2C19 HTR1A HTR7 MAOA SLC6A4
8
Show member pathways
11.39 CYP1A2 CYP2C19 CYP3A4
9 11.32 CYP1A2 CYP2C19 CYP3A4
10
Show member pathways
11.31 CYP1A2 CYP2C19 CYP3A4 SLC6A4
11
Show member pathways
11.24 MAOA SLC6A4
12 11.15 CYP1A2 CYP3A4
13
Show member pathways
11.13 CYP1A2 CYP3A4
14 11.1 CYP2C19 CYP3A4
15
Show member pathways
11.09 CYP1A2 CYP2C19 CYP3A4
16
Show member pathways
11.02 CYP1A2 CYP3A4
17 11 CYP1A2 CYP2C19 MAOA
18
Show member pathways
10.99 MAOA SLC6A4
19
Show member pathways
10.95 CYP1A2 CYP3A4
20 10.94 CYP1A2 CYP3A4
21 10.91 CYP1A2 CYP3A4
22
Show member pathways
10.71 CYP1A2 CYP3A4
23 10.37 HTR1A HTR7 MAOA SLC6A4

GO Terms for Kleptomania

Cellular components related to Kleptomania according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 organelle membrane GO:0031090 8.8 CYP1A2 CYP2C19 CYP3A4

Biological processes related to Kleptomania according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 steroid metabolic process GO:0008202 9.67 CYP1A2 CYP2C19 CYP3A4
2 xenobiotic metabolic process GO:0006805 9.63 CYP1A2 CYP2C19 CYP3A4
3 G protein-coupled serotonin receptor signaling pathway GO:0098664 9.54 HTR1A HTR7
4 long-chain fatty acid biosynthetic process GO:0042759 9.52 CYP1A2 CYP3A4
5 epoxygenase P450 pathway GO:0019373 9.51 CYP1A2 CYP2C19
6 drug metabolic process GO:0017144 9.5 CYP1A2 CYP2C19 CYP3A4
7 omega-hydroxylase P450 pathway GO:0097267 9.48 CYP1A2 CYP2C19
8 oxidative demethylation GO:0070989 9.43 CYP1A2 CYP3A4
9 exogenous drug catabolic process GO:0042738 9.43 CYP1A2 CYP2C19 CYP3A4
10 drug catabolic process GO:0042737 9.4 CYP1A2 CYP3A4
11 steroid catabolic process GO:0006706 9.37 CYP1A2 CYP3A4
12 vasoconstriction GO:0042310 9.33 HTR1A HTR7 SLC6A4
13 heterocycle metabolic process GO:0046483 9.13 CYP1A2 CYP2C19 CYP3A4
14 monoterpenoid metabolic process GO:0016098 8.8 CYP1A2 CYP2C19 CYP3A4

Molecular functions related to Kleptomania according to GeneCards Suite gene sharing:

(show all 12)
# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.78 CYP1A2 CYP2C19 CYP3A4 MAOA
2 iron ion binding GO:0005506 9.58 CYP1A2 CYP2C19 CYP3A4
3 neurotransmitter receptor activity GO:0030594 9.51 HTR1A HTR7
4 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.5 CYP1A2 CYP2C19 CYP3A4
5 oxygen binding GO:0019825 9.49 CYP2C19 CYP3A4
6 G protein-coupled serotonin receptor activity GO:0004993 9.46 HTR1A HTR7
7 steroid hydroxylase activity GO:0008395 9.43 CYP2C19 CYP3A4
8 monooxygenase activity GO:0004497 9.43 CYP1A2 CYP2C19 CYP3A4
9 serotonin binding GO:0051378 9.37 HTR1A SLC6A4
10 heme binding GO:0020037 9.26 ABCB6 CYP1A2 CYP2C19 CYP3A4
11 caffeine oxidase activity GO:0034875 9.16 CYP1A2 CYP3A4
12 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 8.8 CYP1A2 CYP2C19 CYP3A4

Sources for Kleptomania

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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