Aliases & Classifications for Kleptomania

MalaCards integrated aliases for Kleptomania:

Name: Kleptomania 12 15 74
Pathological Stealing 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12400
ICD9CM 36 312.32
MeSH 45 D007174
NCIt 51 C94333
SNOMED-CT 69 69361009
ICD10 34 F63.2
UMLS 74 C0022734

Summaries for Kleptomania

Disease Ontology : 12 An impulse control disorder that involves the repeated impulse to steal for no great gain, when he or she has sufficient money to pay for the item and no need for what is stolen.

MalaCards based summary : Kleptomania, also known as pathological stealing, is related to exhibitionism and pathological gambling. An important gene associated with Kleptomania is ABCB6 (ATP Binding Cassette Subfamily B Member 6 (Langereis Blood Group)), and among its related pathways/superpathways are Drug metabolism - cytochrome P450 and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Carbidopa and Dopamine have been mentioned in the context of this disorder. Affiliated tissues include skin and testes, and related phenotype is homeostasis/metabolism.

Wikipedia : 77 Kleptomania is the inability to refrain from the urge for stealing items and is usually done for reasons... more...

Related Diseases for Kleptomania

Diseases related to Kleptomania via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 61)
# Related Disease Score Top Affiliating Genes
1 exhibitionism 30.4 ABCB6 MAOA
2 pathological gambling 30.4 MAOA SLC6A4
3 depression 30.4 HTR1A MAOA SLC6A4
4 personality disorder 30.2 HTR1A MAOA SLC6A4
5 obsessive-compulsive disorder 30.1 HTR1A MAOA SLC6A4 SLITRK1
6 mood disorder 29.9 HTR1A MAOA SLC6A4
7 attention deficit-hyperactivity disorder 29.7 HTR1A MAOA SLC6A4
8 schizophrenia 29.3 CYP1A2 HTR1A MAOA SLC6A4
9 major depressive disorder 28.9 CYP2C19 GATA3 HTR1A MAOA SLC6A4
10 pyromania 11.2
11 stereotypic movement disorder 10.3 ABCB6 SLITRK1
12 trichotillomania 10.3 ABCB6 SLITRK1
13 paraphilia disorder 10.2 ABCB6 MAOA
14 neurotic excoriation 10.2 PPIG SLITRK1
15 psychosexual disorder 10.2 HTR1A SLC6A4
16 sexual disorder 10.2 HTR1A SLC6A4
17 avoidant personality disorder 10.2 MAOA SLC6A4
18 atypical depressive disorder 10.2 MAOA SLC6A4
19 periodic limb movement disorder 10.2 HTR1A SLC6A4
20 premature ejaculation 10.1 HTR1A SLC6A4
21 pol iii-related leukodystrophies 10.1
22 alexithymia 10.1 HTR1A SLC6A4
23 intermittent explosive disorder 10.1 HTR1A SLC6A4
24 oppositional defiant disorder 10.1 MAOA SLC6A4
25 esophageal candidiasis 10.1 CYP2C19 CYP3A4
26 dependent personality disorder 10.1 CYP3A4 MAOA
27 antisocial personality disorder 10.0 MAOA SLC6A4
28 paranoid schizophrenia 10.0 MAOA SLC6A4
29 phobic disorder 10.0 HTR1A MAOA SLC6A4
30 migraine without aura 10.0 HTR1A SLC6A4
31 social phobia 10.0 HTR1A MAOA SLC6A4
32 postpartum depression 10.0 MAOA SLC6A4
33 agoraphobia 10.0 HTR1A MAOA SLC6A4
34 brunner syndrome 10.0 HTR1A MAOA SLC6A4
35 borderline personality disorder 10.0 HTR1A MAOA SLC6A4
36 bulimia nervosa 10.0
37 fetishism 10.0
38 epilepsy 10.0
39 eating disorder 10.0
40 endogenous depression 10.0 HTR1A MAOA SLC6A4
41 generalized anxiety disorder 10.0 HTR1A MAOA SLC6A4
42 chronic fatigue syndrome 10.0 HTR1A MAOA SLC6A4
43 panic disorder 10.0 HTR1A MAOA SLC6A4
44 disease of mental health 10.0 HTR1A MAOA SLC6A4
45 migraine with or without aura 1 10.0 HTR1A MAOA SLC6A4
46 dyspepsia 10.0 CYP2C19 HTR1A SLC6A4
47 bipolar i disorder 10.0 HTR1A SLC6A4
48 hepatocellular adenoma 10.0 CYP1A2 CYP3A4
49 sudden infant death syndrome 9.9 HTR1A MAOA SLC6A4
50 dementia 9.9

Graphical network of the top 20 diseases related to Kleptomania:



Diseases related to Kleptomania

Symptoms & Phenotypes for Kleptomania

MGI Mouse Phenotypes related to Kleptomania:

47
# Description MGI Source Accession Score Top Affiliating Genes
1 homeostasis/metabolism MP:0005376 9.23 ABCB6 CYP1A2 GATA3 HTR1A MAOA SLC6A4

Drugs & Therapeutics for Kleptomania

Drugs for Kleptomania (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 22)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Carbidopa Approved Phase 3 28860-95-9 34359
2
Dopamine Approved Phase 3,Phase 2 62-31-7, 51-61-6 681
3
Levodopa Approved Phase 3 59-92-7 6047
4 Neurotransmitter Agents Phase 3,Phase 2
5 Adjuvants, Immunologic Phase 3
6 Antiparkinson Agents Phase 3,Phase 2
7 Immunologic Factors Phase 3
8 Dopamine agonists Phase 3
9 Aromatic Amino Acid Decarboxylase Inhibitors Phase 3
10 Carbidopa, levodopa drug combination Phase 3
11 Dopamine Agents Phase 3,Phase 2
12
Ethanol Approved Phase 2,Not Applicable 64-17-5 702
13
Naltrexone Approved, Investigational, Vet_approved Phase 2 16590-41-3 5360515
14
Memantine Approved, Investigational Phase 2 19982-08-2 4054
15 Narcotic Antagonists Phase 2
16 Peripheral Nervous System Agents Phase 2
17 Narcotics Phase 2
18 Excitatory Amino Acid Antagonists Phase 2
19 Excitatory Amino Acids Phase 2
20 Central Nervous System Depressants Not Applicable
21 Anti-Infective Agents Not Applicable
22 Anti-Infective Agents, Local Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Safety/Efficacy Study of Levodopa-Carbidopa Intestinal Gel in Parkinson's Subjects Completed NCT00360568 Phase 3 Levodopa-carbidopa intestinal gel
2 Levodopa-Carbidopa Intestinal Gel Open-Label Study in Advanced Parkinson's Disease Completed NCT00335153 Phase 3 Levodopa-carbidopa intestinal gel
3 Double-Blind Naltrexone in Kleptomania Completed NCT00332579 Phase 2 Naltrexone;Placebo
4 Memantine in the Treatment of Kleptomania Completed NCT00880685 Phase 2 Memantine
5 Alcohol Related Impairment and Reinforcement: Pre to Post Roux en Y Gastric Bypass Surgery Recruiting NCT02370732 Not Applicable

Search NIH Clinical Center for Kleptomania

Genetic Tests for Kleptomania

Anatomical Context for Kleptomania

MalaCards organs/tissues related to Kleptomania:

42
Skin, Testes

Publications for Kleptomania

Articles related to Kleptomania:

(show top 50) (show all 99)
# Title Authors Year
1
Aripiprazole-induced kleptomania: Case report. ( 29884322 )
2019
2
Exposure and response prevention therapy augmented with naltrexone in kleptomania: a controlled case study using galvanic skin response for monitoring. ( 30894239 )
2019
3
Stealing behavior and impulsivity in individuals with kleptomania who have been arrested for shoplifting. ( 29127886 )
2018
4
Symptom severity and its clinical correlates in kleptomania. ( 29697710 )
2018
5
Kleptomania or common theft - diagnostic and judicial difficulties. ( 29704416 )
2018
6
Imaging studies of kleptomania in a middle-aged woman with obsessive-compulsive disorder: a case report. ( 29987861 )
2018
7
Kleptomania: Recent Advances in Symptoms, Etiology and Treatment. ( 30341533 )
2018
8
Kleptomania and Co-morbid addictive disorders. ( 28142063 )
2017
9
Impairments of kleptomania: what are they? ( 28813121 )
2017
10
A case of venlafaxine-induced kleptomania. ( 26706250 )
2016
11
Kleptomania following hypoxic-ischaemic damage to bilateral caudate nuclei. ( 26825938 )
2016
12
Self-Limited Kleptomania Symptoms as a Side Effect of Duloxetine. ( 28018697 )
2016
13
Treating kleptomania: cross-cultural adaptation of the Kleptomania Symptom Assessment Scale and assessment of an outpatient program. ( 25306380 )
2015
14
Cross-cultural comparison of compulsive stealing (kleptomania). ( 25696786 )
2015
15
The possible effect of methylphenidate on kleptomania in a school-age girl with attention-deficit/hyperactivity disorder. ( 24122344 )
2014
16
Emergence of kleptomania during treatment for obsessive compulsive disorder with fluvoxamine. ( 24574573 )
2014
17
Kleptomania: Beyond serotonin. ( 25540525 )
2014
18
Kleptomania: a case series. ( 25630329 )
2014
19
Memantine reduces stealing behavior and impulsivity in kleptomania: a pilot study. ( 23299454 )
2013
20
Kleptomania in patients with neuro-Behçet's disease. ( 23920112 )
2013
21
Quetiapine-associated pathological stealing in an adolescent girl. ( 23487235 )
2013
22
Suicide attempts in 107 adolescents and adults with kleptomania. ( 23137224 )
2012
23
Naltrexone treatment of kleptomania: a case report. ( 23225130 )
2012
24
Kleptomania treated with tolcapone, a catechol-O-methyl-transferase (COMT) inhibitor. ( 21062636 )
2011
25
An adolescent with kleptomania and attention-deficit/hyperactivity disorder treated with methylphenidate. ( 21823916 )
2011
26
Kleptomania and potential exacerbating factors: a review and case report. ( 22132369 )
2011
27
Pathological stealing in dementia: poor response to SSRI medications. ( 21450164 )
2011
28
Pathological stealing in a patient with systemic lupus erythematosus: rare or hidden? ( 21546413 )
2011
29
Kleptomania, an unusual impulsive control disorder in Parkinson's disease? ( 20202886 )
2010
30
Kleptomania: clinical characteristics and relationship to substance use disorders. ( 20575650 )
2010
31
A double-blind, placebo-controlled study of the opiate antagonist, naltrexone, in the treatment of kleptomania. ( 19217077 )
2009
32
Legal consequences of kleptomania. ( 19813092 )
2009
33
Gender-related differences in individuals seeking treatment for kleptomania. ( 18323758 )
2008
34
Neuropsychological functioning in kleptomania. ( 17007811 )
2007
35
Escitalopram treatment of kleptomania: an open-label trial followed by double-blind discontinuation. ( 17388713 )
2007
36
Epilepsy and kleptomania. ( 17905665 )
2007
37
Understanding and treating kleptomania: new models and new treatments. ( 16910369 )
2006
38
White matter integrity in kleptomania: a pilot study. ( 16956753 )
2006
39
A Structured Clinical Interview for Kleptomania (SCI-K): preliminary validity and reliability testing. ( 19722289 )
2006
40
Outcome study of kleptomania patients treated with naltrexone: a chart review. ( 15711433 )
2005
41
Quality of life in kleptomania and pathological gambling. ( 15714192 )
2005
42
Re: Co-occurrence of personality disorders in persons with kleptomania: a preliminary investigation. ( 16186216 )
2005
43
Kleptomania: comorbid psychiatric diagnosis in patients and their families. ( 15057031 )
2004
44
Dissociative symptoms in kleptomania. ( 15077751 )
2004
45
A case of kleptomania correlating with premenstrual dysphoria. ( 15163267 )
2004
46
Comorbid psychiatric diagnoses in kleptomania and pathological gambling: a preliminary comparison study. ( 15276663 )
2004
47
Kleptomania after head trauma: two case reports and combination treatment strategies. ( 15602100 )
2004
48
Overview of Kleptomania and Phenomenological Description of 40 Patients. ( 15614312 )
2004
49
Co-occurrence of personality disorders in persons with kleptomania: a preliminary investigation. ( 15704625 )
2004
50
Topiramate for the treatment of kleptomania: a case series and review of the literature. ( 12567156 )
2003

Variations for Kleptomania

Expression for Kleptomania

Search GEO for disease gene expression data for Kleptomania.

Pathways for Kleptomania

Pathways related to Kleptomania according to GeneCards Suite gene sharing:

(show all 21)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.56 CYP1A2 CYP2C19 CYP3A4 MAOA TYMP
2 11.83 GATA3 HTR1A MAOA SLC6A4
3
Show member pathways
11.75 CYP1A2 CYP2C19 CYP3A4
4
Show member pathways
11.63 CYP1A2 CYP2C19 CYP3A4 MAOA
5
Show member pathways
11.48 CYP1A2 CYP2C19 CYP3A4
6
Show member pathways
11.39 CYP1A2 CYP2C19 CYP3A4
7 11.34 CYP1A2 CYP2C19 CYP3A4
8 11.32 CYP2C19 HTR1A MAOA SLC6A4
9
Show member pathways
11.23 MAOA SLC6A4
10 11.14 CYP1A2 CYP3A4
11
Show member pathways
11.14 CYP1A2 CYP2C19 CYP3A4
12
Show member pathways
11.12 CYP1A2 CYP3A4
13 11.08 CYP2C19 CYP3A4
14
Show member pathways
11.05 CYP1A2 CYP2C19 CYP3A4 SLC6A4
15
Show member pathways
11.04 CYP1A2 CYP3A4
16 11 CYP1A2 CYP2C19 MAOA
17
Show member pathways
10.99 MAOA SLC6A4
18 10.93 CYP1A2 CYP3A4
19 10.9 CYP1A2 CYP3A4
20 10.78 HTR1A MAOA SLC6A4
21
Show member pathways
10.73 CYP1A2 CYP3A4

GO Terms for Kleptomania

Cellular components related to Kleptomania according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 organelle membrane GO:0031090 8.8 CYP1A2 CYP2C19 CYP3A4

Biological processes related to Kleptomania according to GeneCards Suite gene sharing:

(show all 14)
# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.84 CYP1A2 CYP2C19 CYP3A4 MAOA
2 steroid metabolic process GO:0008202 9.65 CYP1A2 CYP2C19 CYP3A4
3 xenobiotic metabolic process GO:0006805 9.58 CYP1A2 CYP2C19 CYP3A4
4 long-chain fatty acid biosynthetic process GO:0042759 9.52 CYP1A2 CYP3A4
5 epoxygenase P450 pathway GO:0019373 9.51 CYP1A2 CYP2C19
6 vasoconstriction GO:0042310 9.49 HTR1A SLC6A4
7 omega-hydroxylase P450 pathway GO:0097267 9.46 CYP1A2 CYP2C19
8 oxidative demethylation GO:0070989 9.43 CYP1A2 CYP3A4
9 drug metabolic process GO:0017144 9.43 CYP1A2 CYP2C19 CYP3A4
10 drug catabolic process GO:0042737 9.37 CYP1A2 CYP3A4
11 exogenous drug catabolic process GO:0042738 9.33 CYP1A2 CYP2C19 CYP3A4
12 steroid catabolic process GO:0006706 9.32 CYP1A2 CYP3A4
13 heterocycle metabolic process GO:0046483 9.13 CYP1A2 CYP2C19 CYP3A4
14 monoterpenoid metabolic process GO:0016098 8.8 CYP1A2 CYP2C19 CYP3A4

Molecular functions related to Kleptomania according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidoreductase activity GO:0016491 9.76 CYP1A2 CYP2C19 CYP3A4 MAOA
2 iron ion binding GO:0005506 9.58 CYP1A2 CYP2C19 CYP3A4
3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.5 CYP1A2 CYP2C19 CYP3A4
4 oxygen binding GO:0019825 9.48 CYP2C19 CYP3A4
5 steroid hydroxylase activity GO:0008395 9.43 CYP2C19 CYP3A4
6 monooxygenase activity GO:0004497 9.43 CYP1A2 CYP2C19 CYP3A4
7 serotonin binding GO:0051378 9.37 HTR1A SLC6A4
8 heme binding GO:0020037 9.26 ABCB6 CYP1A2 CYP2C19 CYP3A4
9 caffeine oxidase activity GO:0034875 9.16 CYP1A2 CYP3A4
10 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 8.8 CYP1A2 CYP2C19 CYP3A4

Sources for Kleptomania

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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