Aliases & Classifications for Kleptomania

MalaCards integrated aliases for Kleptomania:

Name: Kleptomania 12 15 70
Pathological Stealing 12

Classifications:



External Ids:

Disease Ontology 12 DOID:12400
ICD9CM 34 312.32
MeSH 44 D007174
NCIt 50 C94333
SNOMED-CT 67 69361009
ICD10 32 F63.2
UMLS 70 C0022734

Summaries for Kleptomania

Disease Ontology : 12 An impulse control disorder that involves the repeated impulse to steal for no great gain, when he or she has sufficient money to pay for the item and no need for what is stolen.

MalaCards based summary : Kleptomania, also known as pathological stealing, is related to pyromania and eating disorder. An important gene associated with Kleptomania is DLGAP3 (DLG Associated Protein 3), and among its related pathways/superpathways are Transmission across Chemical Synapses and Sudden Infant Death Syndrome (SIDS) Susceptibility Pathways. The drugs Dopamine and Memantine have been mentioned in the context of this disorder. Affiliated tissues include brain, temporal lobe and skin, and related phenotypes are behavior/neurological and nervous system

Wikipedia : 73 Kleptomania is the inability to resist the urge to steal items, usually for reasons other than personal... more...

Related Diseases for Kleptomania

Diseases related to Kleptomania via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 131)
# Related Disease Score Top Affiliating Genes
1 pyromania 31.7 MAOA CHRNA1
2 eating disorder 30.2 SLC6A4 DRD2 COMT ANKK1
3 depression 30.0 SLC6A4 MAOA HTR1A
4 sexual disorder 30.0 SLC6A4 HTR1A
5 mood disorder 29.9 SLC6A4 MAOA HTR1A DRD2 COMT
6 body dysmorphic disorder 29.8 SLC6A4 MAOA DLGAP3
7 melancholia 29.8 SLC6A4 MAOA HTR1A
8 obsessive-compulsive disorder 29.7 SLC6A4 MAOA HTR1A DRD2 DLGAP3 COMT
9 anorexia nervosa 29.7 SLC6A4 MAOA HTR1A COMT
10 alcohol use disorder 29.6 SLC6A4 HTR1A DRD2 COMT ANKK1
11 personality disorder 29.6 SLC6A4 MAOA HTR1A DRD2 COMT ANKK1
12 mental depression 29.6 SLC6A4 MAOA HTR1A DRD2 COMT
13 major depressive disorder 29.5 SLC6A4 MAOA HTR1A DRD2 COMT
14 borderline personality disorder 29.5 SLC6A4 MAOA HTR1A DRD2 COMT
15 bulimia nervosa 29.4 SLC6A4 MAOA DRD2 COMT
16 agoraphobia 29.4 SLC6A4 MAOA HTR1A COMT
17 substance abuse 29.3 SLC6A4 MAOA HTR1A DRD2 COMT ANKK1
18 attention deficit-hyperactivity disorder 29.2 SLC6A4 MAOA HTR1A DRD2 COMT ANKK1
19 antisocial personality disorder 29.2 SLC6A4 MAOA DRD2 COMT ANKK1
20 psychotic disorder 29.1 SLC6A4 MAOA HTR1A DRD2 COMT
21 pathological gambling 29.1 SLC6A4 MAOA HTR1A DRD2 COMT ANKK1
22 bipolar disorder 29.1 SLC6A4 MAOA HTR1A DRD2 COMT
23 impulse control disorder 29.0 SLC6A4 MAOA HTR1A GYPE DRD2 DLGAP3
24 tobacco addiction 28.8 SLC6A4 MAOA DRD2 COMT CHRNA1 ANKK1
25 alcohol-induced mental disorder 10.2 SLC6A4 DRD2
26 inhibited male orgasm 10.2 SLC6A4 HTR1A
27 psychosexual disorder 10.2 SLC6A4 HTR1A
28 taqi polymorphism 10.2 DRD2 ANKK1
29 hypochondriasis 10.2 SLC6A4 HTR1A
30 retrograde amnesia 10.2 SLC6A4 HTR1A
31 adjustment disorder 10.2 SLC6A4 HTR1A
32 hallucinogen dependence 10.2 DRD2 ANKK1
33 brain injury 10.2 DRD2 COMT
34 corneal dystrophy, lisch epithelial 10.2 MAOA HTR1A
35 acute stress disorder 10.1 SLC6A4 HTR1A
36 delusional disorder 10.1 HTR1A DRD2
37 diamond-blackfan anemia 5 10.1 SLC6A4 HTR1A
38 avoidant personality disorder 10.1
39 polysubstance abuse 10.1 DRD2 COMT
40 tardive dyskinesia 10.1 DRD2 COMT
41 obsessive-compulsive personality disorder 10.1 SLC6A4 COMT
42 trichotillomania 10.1 MAOA DLGAP3
43 lingual-facial-buccal dyskinesia 10.1 HTR1A DRD2
44 opioid addiction 10.1 DRD2 COMT
45 kagami-ogata syndrome 10.1 SLC6A4 DRD2 DLGAP3
46 opiate dependence 10.1 SLC6A4 DRD2 ANKK1
47 flying phobia 10.1 MAOA COMT
48 sexual sadism 10.1 MAOA COMT
49 drug dependence 10.1 SLC6A4 DRD2 ANKK1
50 paraphilia disorder 10.1 SLC6A4 MAOA DRD2

Graphical network of the top 20 diseases related to Kleptomania:



Diseases related to Kleptomania

Symptoms & Phenotypes for Kleptomania

MGI Mouse Phenotypes related to Kleptomania:

46
# Description MGI Source Accession Score Top Affiliating Genes
1 behavior/neurological MP:0005386 9.61 ARPC5L ARSA CHRNA1 COMT DLGAP3 DRD2
2 nervous system MP:0003631 9.23 ARSA CHRNA1 COMT DLGAP3 DRD2 HTR1A

Drugs & Therapeutics for Kleptomania

Drugs for Kleptomania (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 10)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
Dopamine Approved Phase 2 51-61-6, 62-31-7 681
2
Memantine Approved, Investigational Phase 2 19982-08-2 4054
3
Ethanol Approved Phase 2 64-17-5 702
4
Naltrexone Approved, Investigational, Vet_approved Phase 2 16590-41-3 5360515
5 Dopamine Agents Phase 2
6 Excitatory Amino Acid Antagonists Phase 2
7 Antiparkinson Agents Phase 2
8 Neurotransmitter Agents Phase 2
9 Narcotics Phase 2
10 Narcotic Antagonists Phase 2

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Memantine Treatment of Kleptomania: An Open-Label Study Completed NCT00880685 Phase 2 Memantine
2 A Double-Blind, Placebo-Controlled Study of Naltrexone in Kleptomania Completed NCT00332579 Phase 2 Naltrexone;Placebo

Search NIH Clinical Center for Kleptomania

Genetic Tests for Kleptomania

Anatomical Context for Kleptomania

MalaCards organs/tissues related to Kleptomania:

40
Brain, Temporal Lobe, Skin

Publications for Kleptomania

Articles related to Kleptomania:

(show top 50) (show all 253)
# Title Authors PMID Year
1
Higher Risk Taking and Impaired Probability Judgment in Behavioral Addiction. 61
32574348 2020
2
Zebrafish models of impulsivity and impulse control disorders. 61
32619029 2020
3
Kleptomania as a neglected disorder in psychiatry. 61
32401643 2020
4
Neuropsychiatric Aspects of Impulse Control Disorders. 61
32439020 2020
5
Naltrexone for High-Dose Venlafaxine-Associated Kleptomania. 61
32332474 2020
6
Heightened Negative Affects Associated With Neurotic Personality in Behavioral Addiction. 61
33101082 2020
7
Kleptomania treated with naltrexone in a patient with intellectual disability 61
31845772 2020
8
Validity and reliability of the Japanese version of the kleptomania symptom assessment scale: A comparison between individuals with kleptomania and prisoners in Japan. 61
31707311 2020
9
Trichotillomania comorbidity in a sample enriched for familial obsessive-compulsive disorder. 61
31518848 2019
10
Exposure and response prevention therapy augmented with naltrexone in kleptomania: a controlled case study using galvanic skin response for monitoring. 61
30894239 2019
11
Scales to assess impulsive and compulsive behaviors in Parkinson's disease: Critique and recommendations. 61
31136681 2019
12
Compulsive sexual behavior disorder in obsessive-compulsive disorder: Prevalence and associated comorbidity. 61
31079471 2019
13
Efficacy of Pharmacological Interventions in Targeting Decision-Making Impairments across Substance and Behavioral Addictions. 61
30852805 2019
14
Aripiprazole-induced kleptomania: Case report. 61
29884322 2019
15
Behavioral addictions in bipolar disorders: A systematic review. 61
30420190 2019
16
The Suffering Body: Manipulation and Discomfort in Eating Disorders. 61
30439839 2018
17
Kleptomania: Recent Advances in Symptoms, Etiology and Treatment. 61
30341533 2018
18
Dual diagnosis of obsessive compulsive and compulsive buying disorders: Demographic, clinical, and psychiatric correlates. 61
30081209 2018
19
Imaging studies of kleptomania in a middle-aged woman with obsessive-compulsive disorder: a case report. 61
29987861 2018
20
Symptom severity and its clinical correlates in kleptomania. 61
29697710 2018
21
Kleptomania or common theft - diagnostic and judicial difficulties. 61
29704416 2018
22
Addictive (Non-Drug) and Obsessive-Compulsive Symptoms after Focal Brain Lesions. 61
29145184 2018
23
Stealing behavior and impulsivity in individuals with kleptomania who have been arrested for shoplifting. 61
29127886 2018
24
Behavioral Addictions and Criminal Responsibility. 61
29282238 2017
25
Impairments of kleptomania: what are they? 61
28813121 2017
26
Kleptomania and Co-morbid addictive disorders. 61
28142063 2017
27
Naltrexone in the Treatment of Broadly Defined Behavioral Addictions: A Review and Meta-Analysis of Randomized Controlled Trials. 61
28877518 2017
28
[The Concept and Treatment of Kleptomania]. 61
27703105 2016
29
Naltrexone: A Pan-Addiction Treatment? 61
27401883 2016
30
Behavioral variant of frontotemporal dementia: Fundamental clinical issues associated with prediction of pathological bases. 61
26969837 2016
31
The behavioral variant of frontotemporal dementia: An analysis of the literature and a case report. 61
27143117 2016
32
Behavioural addiction-A rising tide? 61
26585600 2016
33
Characteristics and correlates of stealing in college students. 61
26648022 2016
34
[ADH/D and impulsiveness: Prevalence of impulse control disorders and other comorbidities, in 81 adults with attention deficit/hyperactivity disorder (ADH/D)]. 61
26928277 2016
35
A case of venlafaxine-induced kleptomania. 61
26706250 2016
36
Opioid antagonists in broadly defined behavioral addictions: a narrative review. 61
26798982 2016
37
Kleptomania following hypoxic-ischaemic damage to bilateral caudate nuclei. 61
26825938 2016
38
Self-Limited Kleptomania Symptoms as a Side Effect of Duloxetine. 61
28018697 2016
39
[Kleptomania and compulsive buying]. 61
26394524 2015
40
Using Star Wars' supporting characters to teach about psychopathology. 61
26104772 2015
41
Cross-cultural comparison of compulsive stealing (kleptomania). 61
25696786 2015
42
The relationship of DSM-IV pathological gambling to compulsive buying and other possible spectrum disorders: results from the Iowa PG family study. 61
25660732 2015
43
Treating kleptomania: cross-cultural adaptation of the Kleptomania Symptom Assessment Scale and assessment of an outpatient program. 61
25306380 2015
44
[Comorbodity of kleptomania and eating disorders]. 61
25909797 2015
45
Kleptomania: a case series. 61
25630329 2014
46
Kleptomania: Beyond serotonin. 61
25540525 2014
47
Impulse control disorders in elderly patients. 61
24405774 2014
48
The possible effect of methylphenidate on kleptomania in a school-age girl with attention-deficit/hyperactivity disorder. 61
24122344 2014
49
Emergence of kleptomania during treatment for obsessive compulsive disorder with fluvoxamine. 61
24574573 2014
50
Compulsive sexual behavior in young adults. 61
23926574 2013

Variations for Kleptomania

Expression for Kleptomania

Search GEO for disease gene expression data for Kleptomania.

Pathways for Kleptomania

Pathways related to Kleptomania according to GeneCards Suite gene sharing:

(show all 11)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
12.51 SLC6A4 MAOA DLGAP3 COMT CHRNA1
2 11.84 SLC6A4 MAOA HTR1A
3 11.56 SLC6A4 MAOA HTR1A
4
Show member pathways
11.13 SLC6A4 MAOA
5
Show member pathways
10.82 MAOA COMT
6 10.78 SLC6A4 MAOA HTR1A
7 10.73 DRD2 ANKK1
8
Show member pathways
10.58 MAOA COMT
9
Show member pathways
10.55 SLC6A4 MAOA COMT
10 10.51 MAOA COMT
11
Show member pathways
10.38 SLC6A4 MAOA HTR1A DRD2 COMT

GO Terms for Kleptomania

Cellular components related to Kleptomania according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 integral component of plasma membrane GO:0005887 9.35 SLC6A4 HTR1A GYPE DRD2 CHRNA1
2 integral component of postsynaptic membrane GO:0099055 9.16 SLC6A4 DRD2
3 synapse GO:0045202 9.1 SLC6A4 HTR1A DRD2 DLGAP3 CHRNA1 ARPC5L

Biological processes related to Kleptomania according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 vasoconstriction GO:0042310 9.32 SLC6A4 HTR1A
2 dopamine metabolic process GO:0042417 9.26 DRD2 COMT
3 catecholamine metabolic process GO:0006584 9.16 MAOA COMT
4 neurotransmitter catabolic process GO:0042135 8.96 MAOA COMT
5 dopamine catabolic process GO:0042420 8.62 MAOA COMT

Molecular functions related to Kleptomania according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 serotonin binding GO:0051378 8.62 SLC6A4 HTR1A

Sources for Kleptomania

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
20 GARD
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
53 NINDS
54 Novoseek
56 OMIM via Orphanet
57 OMIM® (Updated 20-May-2021)
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 Tocris
70 UMLS
71 UMLS via Orphanet
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