Aliases & Classifications for Koro

MalaCards integrated aliases for Koro:

Name: Koro 53 73
Genital Retraction Syndrome 53
Koro Syndrome 53
Suo Yang 53

Classifications:



External Ids:

UMLS 73 C0085429

Summaries for Koro

MalaCards based summary : Koro, also known as genital retraction syndrome, is related to schizophrenia and anxiety. An important gene associated with Koro is ALB (Albumin), and among its related pathways/superpathways are Linoleic acid metabolism and Statin Pathway - Generalized, Pharmacokinetics. The drugs Calcium, Dietary and chloroquine have been mentioned in the context of this disorder. Affiliated tissues include brain.

Wikipedia : 76 Koro is a culture-specific syndrome delusional disorder in which an individual has an overpowering... more...

Related Diseases for Koro

Diseases related to Koro via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 19)
# Related Disease Score Top Affiliating Genes
1 schizophrenia 10.1
2 anxiety 10.1
3 phenytoin toxicity 10.0 ALB CYP2C9
4 infertility 10.0
5 capgras syndrome 10.0
6 depression 10.0
7 analbuminemia 9.9 ALB OXA1L
8 hypertensive nephropathy 9.9 ALB CYP3A4
9 esophageal candidiasis 9.8 CYP2C9 CYP3A4
10 hypochondriasis 9.8
11 psychotic disorder 9.8
12 panic disorder 9.8
13 cerebrovascular disease 9.8
14 measles 9.8
15 clopidogrel resistance 9.8 CYP2C9 CYP3A4
16 hepatopulmonary syndrome 9.5 ALB EDNRA
17 portal hypertension 9.4 ALB EDNRA
18 diarrhea 9.3 ALB CYP3A4
19 autosomal dominant polycystic kidney disease 9.3 ALB EDNRA

Graphical network of the top 20 diseases related to Koro:



Diseases related to Koro

Symptoms & Phenotypes for Koro

Drugs & Therapeutics for Koro

Drugs for Koro (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 30)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1 Calcium, Dietary Phase 2
2
chloroquine Approved, Investigational, Vet_approved Not Applicable 54-05-7 2719
3
Mefloquine Approved, Investigational Not Applicable 53230-10-7 4046
4
Artesunate Approved, Investigational Not Applicable 88495-63-0 6917864 5464098
5
Miconazole Approved, Investigational, Vet_approved Not Applicable 22916-47-8 4189
6
Sulfadoxine Approved, Investigational Not Applicable 2447-57-6 17134
7
Pyrimethamine Approved, Investigational, Vet_approved Not Applicable 58-14-0 4993
8
Amodiaquine Approved, Investigational Not Applicable 86-42-0 2165
9
Lumefantrine Approved Not Applicable 82186-77-4 6437380
10
Artemether Approved Not Applicable 71963-77-4 119380 68911
11
leucovorin Approved, Nutraceutical Not Applicable 58-05-9 143 6006
12
Folic Acid Approved, Nutraceutical, Vet_approved Not Applicable 59-30-3 6037
13 Chloroquine diphosphate Not Applicable 50-63-5
14 Renal Agents Not Applicable
15 Folic Acid Antagonists Not Applicable
16 Amodiaquine, artesunate drug combination Not Applicable
17 Anthelmintics Not Applicable
18 Vitamin B Complex Not Applicable
19 Fanasil, pyrimethamine drug combination Not Applicable
20 Anti-Infective Agents Not Applicable
21 Antifungal Agents Not Applicable
22 Antiparasitic Agents Not Applicable
23 Antiprotozoal Agents Not Applicable
24 Antimalarials Not Applicable
25 Artemether-lumefantrine combination Not Applicable
26 Artemisinine Not Applicable
27 Artemisinins Not Applicable
28 Antirheumatic Agents Not Applicable
29 Folate Nutraceutical Not Applicable
30 Vitamin B9 Nutraceutical Not Applicable

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Phase 2 Dose-finding IMU-838 for Ulcerative Colitis Recruiting NCT03341962 Phase 2 IMU-838;Placebo
2 PRV-based Detection of CAD in Comparison to Standard Methods Completed NCT02404948
3 Antimalarial Drug Resistance in Mali Completed NCT00127998 Not Applicable chloroquine;sulfadoxine-pyrimethamine;amodiaquine;amodiaquine+artesunate;amodiaquine+sulfadoxine-pyrimethamine;sulfadoxine-pyrimethamine+artesunate;artemether-lumefantrine;mefloquine
4 Optimizing Integrated PMTCT Services in Rural North-Central Nigeria Completed NCT01805752 Not Applicable

Search NIH Clinical Center for Koro

Genetic Tests for Koro

Anatomical Context for Koro

MalaCards organs/tissues related to Koro:

41
Brain

Publications for Koro

Articles related to Koro:

(show top 50) (show all 127)
# Title Authors Year
1
Koro in panic disorder: Beyond a culture bound phenomena. ( 29447990 )
2018
2
Cannabis induced koro in a Nepali migrant. ( 29453146 )
2018
3
Koro: Much more than just a culture bound syndrome. ( 29061414 )
2017
4
Clinical course and treatment outcome of Koro: A follow up study from a Koro epidemic reported from West Bengal, India. ( 28483078 )
2017
5
Koro, Othello and Capgras syndromes in one patient with drug induced psychosis. ( 26609659 )
2015
6
Koro presenting as acute and transient psychosis: implications for classification. ( 25042966 )
2014
7
Epidemic of Koro in North East India: An observational cross-sectional study. ( 25150397 )
2014
8
Schizophrenia presenting with Koro-like symptoms. ( 23487222 )
2013
9
Concurrent Koro and Cotard syndromes in a Spanish male patient with a psychotic depression and cerebrovascular disease. ( 22310658 )
2012
10
Making up koro: multiplicity, psychiatry, culture, and penis-shrinking anxieties. ( 21511718 )
2012
11
Resurgence of Koro: Perception of mankind. ( 23051086 )
2011
12
Koro: culture bound or mass hysteria? ( 21561239 )
2011
13
An outbreak of Koro among 19 workers in a jute mill in south Bengal. ( 22969183 )
2011
14
Koro-like symptoms in two Greek men. ( 22419951 )
2010
15
The cultural myth of Koro conceptualization: time for a rethink. ( 19541758 )
2009
16
Ramadan fasting triggering koro-like symptoms during acute alcohol withdrawal: a case report from Oman. ( 19091733 )
2008
17
Koro--the psychological disappearance of the penis. ( 17727356 )
2007
18
A conceptual history of Koro. ( 17379608 )
2007
19
'Koro' in a 13 years old boy of interior Sindh - a mistreated cultural syndrome. ( 17204227 )
2007
20
[Two cases of koro syndrome or anxiety disorder associated with genital retraction fear]. ( 17853984 )
2007
21
Cannabis-induced koro-like syndrome. A case report and mini review. ( 16601394 )
2006
22
An outbreak of measles, Koro Island, 1997. ( 18181387 )
2006
23
Understanding genital-shrinking epidemics in West Africa: koro, juju, or mass psychogenic illness? ( 16108203 )
2005
24
Chronic koro-like symptoms - two case reports. ( 16221300 )
2005
25
Koro syndrome: a case report. ( 15709651 )
2004
26
Whizz-dick: side effect, urban myth or amfetamine-related koro-like syndrome? ( 15311730 )
2004
27
Koro-misidentification syndrome in schizophrenia? A plea for clinical psychopathology. ( 15353891 )
2004
28
Fluvoxamine treatment of a Japanese patient with koro. ( 12530418 )
2002
29
Cannabis-induced Koro in Americans. ( 11784462 )
2001
30
Treatment of of koro with citalopram. ( 11206606 )
2000
31
Genital pain without urogenital pathology: the koro-like syndrome. ( 10604364 )
2000
32
The Koro syndrome. ( 11293971 )
2000
33
A case of urethrocutaneous fistula with the koro syndrome. ( 10840440 )
2000
34
Koro-like syndrome in a Jordanian male. ( 10793842 )
1999
35
Koro associated with phobia for AIDS. ( 9844839 )
1998
36
Genital retraction syndrome in Korean woman. A case of Koro in Hungary. ( 9697166 )
1998
37
Koro presenting to genitourinary medicine services. ( 9530906 )
1998
38
Emergence of koro after abrupt cessation of olanzapine. ( 9501896 )
1998
39
Koro-like syndrome in a Bedouin man. ( 9697160 )
1998
40
Genital pain associated with genital retraction: a case of Koro syndrome. ( 9114638 )
1997
41
History of Koro in Singapore. ( 9364894 )
1997
42
Koro and homicidal behavior. ( 9247411 )
1997
43
Koro-like syndrome associated with brief reactive psychosis in an Irish male. ( 8682636 )
1996
44
Transculturation, psychosis and koro symptoms. ( 8766434 )
1996
45
A critical review of Chinese Koro. ( 8740959 )
1996
46
Treatment of Koro and panic attacks after stroke. ( 9160601 )
1996
47
Koro in an immigrant from Guinea with brief psychotic disorder. ( 8615432 )
1996
48
The definition and classification of Koro. ( 8740958 )
1996
49
Koro in ancient Chinese history. ( 11618755 )
1996
50
Koro presenting after prostatectomy in an elderly man. ( 7850282 )
1995

Variations for Koro

Expression for Koro

Search GEO for disease gene expression data for Koro.

Pathways for Koro

Pathways related to Koro according to GeneCards Suite gene sharing:

(show all 15)
# Super pathways Score Top Affiliating Genes
1
Show member pathways
11.61 CYP2C9 CYP3A4
2
Show member pathways
11.47 CYP2C9 CYP3A4
3
Show member pathways
11.42 CYP2C9 CYP3A4
4
Show member pathways
11.3 CYP2C9 CYP3A4
5
Show member pathways
11.28 CYP2C9 CYP3A4
6
Show member pathways
11.23 CYP2C9 CYP3A4
7
Show member pathways
11.19 CYP2C9 CYP3A4
8 11.14 CYP2C9 CYP3A4
9 10.95 CYP2C9 CYP3A4
10 10.87 CYP2C9 CYP3A4
11
Show member pathways
10.75 CYP2C9 CYP3A4
12
Show member pathways
10.64 CYP2C9 CYP3A4
13 10.54 CYP2C9 CYP3A4
14 10.26 CYP2C9 CYP3A4
15 9.32 CYP2C9 CYP3A4

GO Terms for Koro

Cellular components related to Koro according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 organelle membrane GO:0031090 8.62 CYP2C9 CYP3A4

Biological processes related to Koro according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 oxidation-reduction process GO:0055114 9.61 CYP2C9 CYP3A4 OXA1L
2 steroid metabolic process GO:0008202 9.4 CYP2C9 CYP3A4
3 xenobiotic metabolic process GO:0006805 9.37 CYP2C9 CYP3A4
4 drug metabolic process GO:0017144 9.32 CYP2C9 CYP3A4
5 exogenous drug catabolic process GO:0042738 9.26 CYP2C9 CYP3A4
6 oxidative demethylation GO:0070989 9.16 CYP2C9 CYP3A4
7 drug catabolic process GO:0042737 8.96 CYP2C9 CYP3A4
8 monoterpenoid metabolic process GO:0016098 8.62 CYP2C9 CYP3A4

Molecular functions related to Koro according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 iron ion binding GO:0005506 9.46 CYP2C9 CYP3A4
2 heme binding GO:0020037 9.43 CYP2C9 CYP3A4
3 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen GO:0016705 9.4 CYP2C9 CYP3A4
4 drug binding GO:0008144 9.37 ALB CYP2C9
5 monooxygenase activity GO:0004497 9.32 CYP2C9 CYP3A4
6 steroid hydroxylase activity GO:0008395 9.26 CYP2C9 CYP3A4
7 oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen GO:0016712 9.16 CYP2C9 CYP3A4
8 caffeine oxidase activity GO:0034875 8.96 CYP2C9 CYP3A4
9 oxygen binding GO:0019825 8.8 ALB CYP2C9 CYP3A4

Sources for Koro

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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