KORO
MCID: KR001
MIFTS: 24

Koro (KORO)

Categories: Rare diseases

Aliases & Classifications for Koro

MalaCards integrated aliases for Koro:

Name: Koro 52 71
Genital Retraction Syndrome 52
Koro Syndrome 52
Suo Yang 52

Classifications:



External Ids:

UMLS 71 C0085429

Summaries for Koro

MalaCards based summary : Koro, also known as genital retraction syndrome, is related to acute cystitis and impotence. An important gene associated with Koro is ALB (Albumin). The drugs leucovorin and Amodiaquine have been mentioned in the context of this disorder. Affiliated tissues include brain and tongue.

Wikipedia : 74 Koro is a culture-bound syndrome delusional disorder in which an individual has an overpowering belief... more...

Related Diseases for Koro

Diseases related to Koro via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 56)
# Related Disease Score Top Affiliating Genes
1 acute cystitis 30.0 OXA1L ALB
2 impotence 29.8 EDNRA ALB
3 depersonalization disorder 10.3
4 mental depression 10.3
5 depression 10.3
6 schizophrenia 10.3
7 anxiety 10.3
8 stroke, ischemic 10.2
9 neurotic disorder 10.2
10 infertility 10.2
11 panic disorder 10.2
12 alzheimer disease 10.0
13 obsessive-compulsive disorder 10.0
14 immune deficiency disease 10.0
15 major depressive disorder 10.0
16 human immunodeficiency virus type 1 10.0
17 inguinal hernia 10.0
18 voyeurism 10.0
19 dysthymic disorder 10.0
20 alcoholic hepatitis 10.0
21 hypochondriasis 10.0
22 psychotic disorder 10.0
23 mood disorder 10.0
24 aids phobia 10.0
25 capgras syndrome 10.0
26 cerebrovascular disease 10.0
27 measles 10.0
28 fainting 10.0
29 red cell aplasia 10.0 OXA1L ALB
30 analbuminemia 10.0 OXA1L ALB
31 hyperthyroxinemia 10.0 OXA1L ALB
32 drug allergy 10.0 OXA1L ALB
33 pure red-cell aplasia 10.0 OXA1L ALB
34 phenytoin toxicity 9.9 CYP2C9 ALB
35 drug-induced hepatitis 9.9 CYP2C9 ALB
36 pulmonary artery disease 9.9 CYP2C9 ALB
37 uremia 9.9 OXA1L ALB
38 heart conduction disease 9.8 CYP2C9 ALB
39 scarlet fever 9.8 EDNRA ALB
40 multidrug-resistant tuberculosis 9.7 EDNRA ALB
41 capillary leak syndrome 9.7 EDNRA ALB
42 persistent fetal circulation syndrome 9.7 EDNRA ALB
43 hepatopulmonary syndrome 9.7 EDNRA ALB
44 headache 9.7 EDNRA ALB
45 commensal bacterial infectious disease 9.7 EDNRA ALB
46 mastitis 9.7 EDNRA ALB
47 intracranial berry aneurysm 9.7 EDNRA ALB
48 portal hypertension 9.6 EDNRA ALB
49 patent foramen ovale 9.6 EDNRA ALB
50 cystic kidney disease 9.6 EDNRA ALB

Graphical network of the top 20 diseases related to Koro:



Diseases related to Koro

Symptoms & Phenotypes for Koro

Drugs & Therapeutics for Koro

Drugs for Koro (from DrugBank, HMDB, Dgidb, PharmGKB, IUPHAR, NovoSeek, BitterDB):

(show all 25)
# Name Status Phase Clinical Trials Cas Number PubChem Id
1
leucovorin Approved 58-05-9 6006 143
2
Amodiaquine Approved, Investigational 86-42-0 2165
3
chloroquine Approved, Investigational, Vet_approved 54-05-7 2719
4
Sulfadoxine Approved, Investigational 2447-57-6 17134
5
Artemether Approved 71963-77-4 68911 9796294 119380
6
Lumefantrine Approved 82186-77-4 6437380
7
Artesunate Approved, Investigational 88495-63-0 6917864 5464098
8
Mefloquine Approved, Investigational 53230-10-7 4046
9
Pyrimethamine Approved, Investigational, Vet_approved 58-14-0 4993
10
Folic acid Approved, Nutraceutical, Vet_approved 59-30-3 6037
11 Anti-Infective Agents
12 Anthelmintics
13 Vitamin B Complex
14 Fanasil, pyrimethamine drug combination
15 Amebicides
16 Chloroquine diphosphate 50-63-5
17 Antiparasitic Agents
18 Folic Acid Antagonists
19 Folate
20 Antiprotozoal Agents
21 Antiviral Agents
22 Antirheumatic Agents
23 Artemether, Lumefantrine Drug Combination
24 Vitamin B9
25 Antimalarials

Interventional clinical trials:


# Name Status NCT ID Phase Drugs
1 Characterization of Novel Molecular Tools for the Epidemiological Surveillance of Antimalarial Drug Resistance in Mali Completed NCT00127998 chloroquine;sulfadoxine-pyrimethamine;amodiaquine;amodiaquine+artesunate;amodiaquine+sulfadoxine-pyrimethamine;sulfadoxine-pyrimethamine+artesunate;artemether-lumefantrine;mefloquine

Search NIH Clinical Center for Koro

Genetic Tests for Koro

Anatomical Context for Koro

MalaCards organs/tissues related to Koro:

40
Brain, Tongue

Publications for Koro

Articles related to Koro:

(show top 50) (show all 188)
# Title Authors PMID Year
1
Sentinel optical and SAR data highlights multi-segment faulting during the 2018 Palu-Sulawesi earthquake (Mw 7.5). 61
32499496 2020
2
In vitro gastrointestinal simulation of tempe prepared from koro kratok (Phaseolus lunatus L.) as an angiotensin-converting enzyme inhibitor. 61
32327795 2020
3
A case of two culture-bound syndromes (Koro and Dhat syndrome) coexisting with obsessive-compulsive disorder. 61
32382189 2020
4
Koro Delusion in Mild Cognitive Impairment Due to Alzheimer's Disease. 61
31530117 2020
5
Update on Koro research methodology. 61
32001941 2020
6
SAR and Optical Data Comparison for Detecting Co-Seismic Slip and Induced Phenomena during the 2018 Mw 7.5 Sulawesi Earthquake. 61
31540119 2019
7
Toxicity Assessment of Chinese Herbal Medicine Cynomorium songaricum Rupr. 61
30949225 2019
8
Koro and denial of genital ownership. 61
30295051 2018
9
n-Propanol extract of boiled and fermented koro benguk (Mucuna pruriens seed) shows a neuroprotective effect in paraquat dichloride-induced Parkinson's disease rat model. 61
30410229 2018
10
The Knowledge Object Reference Ontology (KORO): A formalism to support management and sharing of computable biomedical knowledge for learning health systems. 61
31245583 2018
11
Cannabis induced koro in a Nepali migrant. 61
29453146 2018
12
[Koro syndrome : when culture interacts with psychopathology]. 61
29722492 2018
13
Koro in panic disorder: Beyond a culture bound phenomena. 61
29447990 2018
14
The oughtness of care: Fear, stress, and caregiving during the 2000-2001 Ebola outbreak in Gulu, Uganda. 61
29073506 2017
15
Koro: Much more than just a culture bound syndrome. 61
29061414 2017
16
Cultural aspects of anxiety disorders in India. 61
28867936 2017
17
Clinical course and treatment outcome of Koro: A follow up study from a Koro epidemic reported from West Bengal, India. 61
28483078 2017
18
[Cotard's syndrome: Case report and a brief review of literature]. 61
28114093 2016
19
Koro, Othello and Capgras syndromes in one patient with drug induced psychosis. 61
26609659 2015
20
[Case of koro]. 61
26571886 2015
21
Epidemic of Koro in North East India: an observational cross-sectional study. 61
25150397 2014
22
[Frequency of glucose-6-phosphate dehydrogenase deficiency (A-376/202) in three Malian ethnic groups]. 61
24952161 2014
23
Koro presenting as acute and transient psychosis: implications for classification. 61
25042966 2014
24
Schizophrenia presenting with Koro-like symptoms. 61
23487222 2013
25
Isotopic evidence for an early shift to C₄ resources by Pliocene hominins in Chad. 61
23150583 2012
26
Concurrent Koro and Cotard syndromes in a Spanish male patient with a psychotic depression and cerebrovascular disease. 61
22310658 2012
27
Making up koro: multiplicity, psychiatry, culture, and penis-shrinking anxieties. 61
21511718 2012
28
Koro: culture bound or mass hysteria? 61
21561239 2011
29
Resurgence of Koro: Perception of mankind. 61
23051086 2011
30
[Chronic Koro-like Syndrome (KLS) in recurrent depressive disorder as a variant of Cotard's delusion in an italian male patient. A case report and historical review]. 61
21779103 2011
31
An outbreak of Koro among 19 workers in a jute mill in south Bengal. 61
22969183 2011
32
Cotard syndrome in neurological and psychiatric patients. 61
21037126 2010
33
Koro-like symptoms in two Greek men. 61
22419951 2010
34
The cultural myth of Koro conceptualization: time for a rethink. 61
19541758 2009
35
Ramadan fasting triggering koro-like symptoms during acute alcohol withdrawal: a case report from Oman. 61
19091733 2008
36
Cosmogenic nuclide dating of Sahelanthropus tchadensis and Australopithecus bahrelghazali: Mio-Pliocene hominids from Chad. 61
18305174 2008
37
[Mental illness in the former Dutch Indies--four psychiatric syndromes: amok, latah, koro and neurasthenia]. 61
18237055 2007
38
Koro--the psychological disappearance of the penis. 61
17727356 2007
39
Assessing malaria burden during pregnancy in Mali. 61
17543872 2007
40
Management of malnutrition in rural Mali. 61
17158813 2007
41
A conceptual history of Koro. 61
17379608 2007
42
[Two cases of koro syndrome or anxiety disorder associated with genital retraction fear]. 61
17853984 2007
43
'Koro' in a 13 years old boy of interior Sindh - a mistreated cultural syndrome. 61
17204227 2007
44
[Koro syndrome]. 61
17099860 2006
45
An outbreak of measles, Koro Island, 1997. 61
18181387 2006
46
Human brain evolution and the "Neuroevolutionary Time-depth Principle:" Implications for the Reclassification of fear-circuitry-related traits in DSM-V and for studying resilience to warzone-related posttraumatic stress disorder. 61
16563589 2006
47
Cannabis-induced koro-like syndrome. A case report and mini review. 61
16601394 2006
48
Chronic koro-like symptoms - two case reports. 61
16221300 2005
49
[Koro-like symptoms in a recurrent depressive disorder]. 61
15517135 2005
50
Discovery of the photosynthetic relatives of the "Maltese mushroom" Cynomorium. 61
15969755 2005

Variations for Koro

Expression for Koro

Search GEO for disease gene expression data for Koro.

Pathways for Koro

GO Terms for Koro

Molecular functions related to Koro according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 drug binding GO:0008144 8.62 CYP2C9 ALB

Sources for Koro

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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