MCID: KRS005
MIFTS: 10

Korsakoff's Amnesic Syndrome

Categories: Neuronal diseases

Aliases & Classifications for Korsakoff's Amnesic Syndrome

MalaCards integrated aliases for Korsakoff's Amnesic Syndrome:

Name: Korsakoff's Amnesic Syndrome 54
Alcohol Induced Encephalopathy 72

Classifications:



External Ids:

UMLS 72 C2931917

Summaries for Korsakoff's Amnesic Syndrome

NINDS : 54 Wernicke's encephalopathy is a degenerative brain disorder caused by the lack of thiamine (vitamin B1). It may result from alcohol abuse, dietary deficiencies, prolonged vomiting, eating disorders, or the effects of chemotherapy. B1 deficiency causes damage to the brain's thalamus and hypothalamus. Symptoms include mental confusion, vision problems, coma, hypothermia, low blood pressure, and lack of muscle coordination (ataxia). Korsakoff syndrome (also called Korsakoff's amnesic syndrome) is a memory disorder that results from vitamin B1 deficiency and is associated with alcoholism. Korsakoff's syndrome damages nerve cells and supporting cells in the brain and spinal cord, as well as the part of the brain involved with memory. Symptoms include amnesia, tremor, coma, disorientation, and vision problems, The disorder's main features are problems in acquiring new information or establishing new memories, and in retrieving previous memories. Although Wernicke's and Korsakoff's are related disorders, some scientists believe them to be different stages of the same disorder, which is called Wernicke-Korsakoff syndrome. Wernicke's encephalopathy represents the "acute" phase of the disorder and Korsakoff's amnesic syndrome represents the disorder progressing to a "chronic" or long-lasting stage.

MalaCards based summary : Korsakoff's Amnesic Syndrome, also known as alcohol induced encephalopathy, is related to wernicke-korsakoff syndrome and cerebral beriberi. Affiliated tissues include brain, spinal cord and hypothalamus.

Related Diseases for Korsakoff's Amnesic Syndrome

Diseases related to Korsakoff's Amnesic Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 wernicke-korsakoff syndrome 11.7
2 cerebral beriberi 11.7
3 thrombosis 10.2
4 cavernous sinus thrombosis 10.2
5 glioma 10.2
6 glial tumor 10.2

Graphical network of the top 20 diseases related to Korsakoff's Amnesic Syndrome:



Diseases related to Korsakoff's Amnesic Syndrome

Symptoms & Phenotypes for Korsakoff's Amnesic Syndrome

Drugs & Therapeutics for Korsakoff's Amnesic Syndrome

Search Clinical Trials , NIH Clinical Center for Korsakoff's Amnesic Syndrome

Genetic Tests for Korsakoff's Amnesic Syndrome

Anatomical Context for Korsakoff's Amnesic Syndrome

MalaCards organs/tissues related to Korsakoff's Amnesic Syndrome:

41
Brain, Spinal Cord, Hypothalamus, Thalamus

Publications for Korsakoff's Amnesic Syndrome

Articles related to Korsakoff's Amnesic Syndrome:

# Title Authors PMID Year
1
Nanostructures of hydrated C60 fullerene (C60HyFn) protect rat brain against alcohol impact and attenuate behavioral impairments of alcoholized animals. 38
18289766 2008
2
Bilateral cavernous sinus thrombosis causing Korsakoff's amnesic syndrome. 38
7738577 1995
3
Cognitive brain potentials and psychological deficits in Alzheimer's dementia and Korsakoff's amnesic syndrome. 38
3602227 1987
4
[Hypothalamic glioma with Korsakoff's amnesic syndrome. The problem of memory]. 38
4862262 1967

Variations for Korsakoff's Amnesic Syndrome

Expression for Korsakoff's Amnesic Syndrome

Search GEO for disease gene expression data for Korsakoff's Amnesic Syndrome.

Pathways for Korsakoff's Amnesic Syndrome

GO Terms for Korsakoff's Amnesic Syndrome

Sources for Korsakoff's Amnesic Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 TGDB
71 Tocris
72 UMLS
73 UMLS via Orphanet
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