MCID: KRS005
MIFTS: 10

Korsakoff's Amnesic Syndrome

Categories: Neuronal diseases

Aliases & Classifications for Korsakoff's Amnesic Syndrome

MalaCards integrated aliases for Korsakoff's Amnesic Syndrome:

Name: Korsakoff's Amnesic Syndrome 53
Alcohol Induced Encephalopathy 71

Classifications:



External Ids:

UMLS 71 C2931917

Summaries for Korsakoff's Amnesic Syndrome

NINDS : 53 Wernicke's encephalopathy is a degenerative brain disorder caused by the lack of thiamine (vitamin B1). It may result from alcohol abuse, dietary deficiencies, prolonged vomiting, eating disorders, or the effects of chemotherapy. B1 deficiency causes damage to the brain's thalamus and hypothalamus. Symptoms include mental confusion, vision problems, coma, hypothermia, low blood pressure, and lack of muscle coordination (ataxia). Korsakoff syndrome (also called Korsakoff's amnesic syndrome) is a memory disorder that results from vitamin B1 deficiency and is associated with alcoholism. Korsakoff's syndrome damages nerve cells and supporting cells in the brain and spinal cord, as well as the part of the brain involved with memory. Symptoms include amnesia, tremor, coma, disorientation, and vision problems, The disorder's main features are problems in acquiring new information or establishing new memories, and in retrieving previous memories. Although Wernicke's and Korsakoff's are related disorders, some scientists believe them to be different stages of the same disorder, which is called Wernicke-Korsakoff syndrome. Wernicke's encephalopathy represents the "acute" phase of the disorder and Korsakoff's amnesic syndrome represents the disorder progressing to a "chronic" or long-lasting stage.

MalaCards based summary : Korsakoff's Amnesic Syndrome, also known as alcohol induced encephalopathy, is related to wernicke-korsakoff syndrome and cerebral beriberi. Affiliated tissues include brain, spinal cord and thalamus.

Related Diseases for Korsakoff's Amnesic Syndrome

Diseases related to Korsakoff's Amnesic Syndrome via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 wernicke-korsakoff syndrome 11.7
2 cerebral beriberi 11.7
3 thrombosis 10.2
4 cavernous sinus thrombosis 10.2
5 glioma 10.2
6 glial tumor 10.2

Graphical network of the top 20 diseases related to Korsakoff's Amnesic Syndrome:



Diseases related to Korsakoff's Amnesic Syndrome

Symptoms & Phenotypes for Korsakoff's Amnesic Syndrome

Drugs & Therapeutics for Korsakoff's Amnesic Syndrome

Search Clinical Trials , NIH Clinical Center for Korsakoff's Amnesic Syndrome

Genetic Tests for Korsakoff's Amnesic Syndrome

Anatomical Context for Korsakoff's Amnesic Syndrome

MalaCards organs/tissues related to Korsakoff's Amnesic Syndrome:

40
Brain, Spinal Cord, Thalamus, Hypothalamus

Publications for Korsakoff's Amnesic Syndrome

Articles related to Korsakoff's Amnesic Syndrome:

# Title Authors PMID Year
1
Nanostructures of hydrated C60 fullerene (C60HyFn) protect rat brain against alcohol impact and attenuate behavioral impairments of alcoholized animals. 61
18289766 2008
2
Bilateral cavernous sinus thrombosis causing Korsakoff's amnesic syndrome. 61
7738577 1995
3
Cognitive brain potentials and psychological deficits in Alzheimer's dementia and Korsakoff's amnesic syndrome. 61
3602227 1987
4
[Hypothalamic glioma with Korsakoff's amnesic syndrome. The problem of memory]. 61
4862262 1967

Variations for Korsakoff's Amnesic Syndrome

Expression for Korsakoff's Amnesic Syndrome

Search GEO for disease gene expression data for Korsakoff's Amnesic Syndrome.

Pathways for Korsakoff's Amnesic Syndrome

GO Terms for Korsakoff's Amnesic Syndrome

Sources for Korsakoff's Amnesic Syndrome

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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