MCID: KNJ001
MIFTS: 21

Kunjin Encephalitis

Categories: Infectious diseases, Neuronal diseases

Aliases & Classifications for Kunjin Encephalitis

MalaCards integrated aliases for Kunjin Encephalitis:

Name: Kunjin Encephalitis 12 15

Classifications:



External Ids:

Disease Ontology 12 DOID:0050174

Summaries for Kunjin Encephalitis

Disease Ontology : 12 A West Nile encephalitis that results in infection located in brain, has material basis in Kunjin virus, a subtype of West Nile Virus, which is transmitted by Culex annulirostris mosquito bite. The infection has symptom fever, has symptom rigor, has symptom headache, has symptom confusion, and has symptom lethargy.

MalaCards based summary : Kunjin Encephalitis is related to kyasanur forest disease and st. louis encephalitis, and has symptoms including fever, headache and lethargy. An important gene associated with Kunjin Encephalitis is LTV1 (LTV1 Ribosome Biogenesis Factor), and among its related pathways/superpathways are Shigellosis and UVA-Induced MAPK Signaling. Affiliated tissues include brain.

Related Diseases for Kunjin Encephalitis

Diseases related to Kunjin Encephalitis via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 51)
# Related Disease Score Top Affiliating Genes
1 kyasanur forest disease 10.2 SENP8 CD40LG
2 st. louis encephalitis 10.2 SENP8 CD40LG
3 acalculous cholecystitis 10.2 SENP8 CD40LG
4 asymptomatic dengue 10.2 SENP8 CD40LG
5 erythema infectiosum 10.2 SENP8 CD40LG
6 murray valley encephalitis 10.2 SENP8 CD40LG
7 acute hemorrhagic encephalitis 10.2 SENP8 CD40LG
8 early yaws 10.1 JUN CD40LG
9 adult brain stem glioma 10.1 H3-3B H3-3A
10 brain stem glioma 10.1 H3-3B H3-3A
11 bone giant cell sarcoma 10.1 H3-3B H3-3A
12 malignant giant cell tumor 10.1 H3-3B H3-3A
13 spinal cord astrocytoma 10.0 H3-3B H3-3A
14 pneumoconiosis due to talc 10.0 H3-3B H3-3A
15 mental retardation, autosomal dominant 56 10.0 H3-3B H3-3A
16 herpangina 10.0 STAT2 CD40LG
17 clear cell chondrosarcoma 10.0 H3-3B H3-3A
18 spinal cord glioma 10.0 H3-3B H3-3A
19 zika fever 10.0 STAT2 SENP8 CD40LG
20 cataract 34, multiple types 10.0 SRSF7 GGCT
21 dengue shock syndrome 10.0 SENP8 CD40LG
22 childhood brain stem glioma 10.0 H3-3B H3-3A
23 brain stem cancer 10.0 H3-3B H3-3A
24 fibrillary astrocytoma 9.9 H3-3B H3-3A
25 bone giant cell tumor 9.9 H3-3B H3-3A
26 loeys-dietz syndrome 2 9.9 SRSF7 GGCT
27 cataract 4, multiple types 9.9 SRSF7 GGCT
28 cardiomyopathy, familial hypertrophic, 25 9.9 JUN GGCT
29 chondroblastoma 9.9 H3-3B H3-3A
30 exanthem 9.9 SENP8 CD40LG
31 babesiosis 9.8 HUWE1 CD40LG
32 benign giant cell tumor 9.7 H3-3B H3-3A
33 theileriasis 9.7 JUN HUWE1
34 cryptosporidiosis 9.7 HUWE1 CD40LG
35 dysentery 9.6 HUWE1 CD40LG
36 giant cell glioblastoma 9.5 H3-3B H3-3A
37 congenital disorder of glycosylation, type il 9.5 HUWE1 H3-3B H3-3A
38 amelogenesis imperfecta, type ia 9.5 HUWE1 H3-3B H3-3A
39 neurodegeneration with brain iron accumulation 6 9.5 HUWE1 H3-3B H3-3A
40 actinomycosis 9.5 HUWE1 H3-3B H3-3A
41 hypotrichosis 2 9.5 HUWE1 H3-3B H3-3A
42 mulibrey nanism 9.4 HUWE1 H3-3B H3-3A
43 griscelli syndrome, type 2 9.4 HUWE1 H3-3B H3-3A
44 hypotrichosis 1 9.4 HUWE1 H3-3B H3-3A
45 stuttering 9.4 HUWE1 H3-3B H3-3A
46 distal arthrogryposis 9.4 SRSF7 HUWE1 GGCT
47 amelogenesis imperfecta, type if 9.0 HUWE1 H3-3B H3-3A GGCT
48 pelizaeus-merzbacher disease 9.0 HUWE1 H3-3B H3-3A GGCT
49 eye disease 9.0 JUN HUWE1 GGCT CD40LG
50 noonan syndrome 1 8.4 STAT2 HUWE1 H3-3B H3-3A GGCT CD40LG

Graphical network of the top 20 diseases related to Kunjin Encephalitis:



Diseases related to Kunjin Encephalitis

Symptoms & Phenotypes for Kunjin Encephalitis

Symptoms:

12
  • fever
  • headache
  • lethargy
  • confusion
  • rigor

Drugs & Therapeutics for Kunjin Encephalitis

Search Clinical Trials , NIH Clinical Center for Kunjin Encephalitis

Genetic Tests for Kunjin Encephalitis

Anatomical Context for Kunjin Encephalitis

The Foundational Model of Anatomy Ontology organs/tissues related to Kunjin Encephalitis:

19
Brain

MalaCards organs/tissues related to Kunjin Encephalitis:

40
Brain

Publications for Kunjin Encephalitis

Variations for Kunjin Encephalitis

Expression for Kunjin Encephalitis

Search GEO for disease gene expression data for Kunjin Encephalitis.

Pathways for Kunjin Encephalitis

Pathways related to Kunjin Encephalitis according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.88 JUN H3-3B H3-3A
2
Show member pathways
11.24 JUN H3-3B H3-3A
3 10.78 H3-3B H3-3A
4 10.76 STAT2 H3-3B H3-3A
5 10.63 JUN CD40LG

GO Terms for Kunjin Encephalitis

Cellular components related to Kunjin Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 nucleoplasm GO:0005654 9.7 STAT2 SRSF7 LTV1 JUN HUWE1 H3-3B
2 nuclear nucleosome GO:0000788 9.26 H3-3B H3-3A
3 Barr body GO:0001740 8.96 H3-3B H3-3A
4 nuclear chromosome GO:0000228 8.8 JUN H3-3B H3-3A

Biological processes related to Kunjin Encephalitis according to GeneCards Suite gene sharing:

(show all 13)
# Name GO ID Score Top Affiliating Genes
1 negative regulation of gene expression, epigenetic GO:0045814 9.52 H3-3B H3-3A
2 embryo implantation GO:0007566 9.51 H3-3B H3-3A
3 oogenesis GO:0048477 9.49 H3-3B H3-3A
4 chromatin silencing at rDNA GO:0000183 9.48 H3-3B H3-3A
5 nucleus organization GO:0006997 9.46 H3-3B H3-3A
6 telomere organization GO:0032200 9.43 H3-3B H3-3A
7 DNA replication-independent nucleosome assembly GO:0006336 9.4 H3-3B H3-3A
8 release of cytochrome c from mitochondria GO:0001836 9.37 JUN GGCT
9 muscle cell differentiation GO:0042692 9.32 H3-3B H3-3A
10 pericentric heterochromatin assembly GO:0031508 9.26 H3-3B H3-3A
11 regulation of centromere complex assembly GO:0090230 9.16 H3-3B H3-3A
12 negative regulation of chromosome condensation GO:1902340 8.96 H3-3B H3-3A
13 telomeric heterochromatin assembly GO:0031509 8.62 H3-3B H3-3A

Molecular functions related to Kunjin Encephalitis according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 RNA polymerase II proximal promoter sequence-specific DNA binding GO:0000978 9.46 STAT2 JUN H3-3B H3-3A
2 nucleosomal DNA binding GO:0031492 9.26 H3-3B H3-3A
3 RNA polymerase II core promoter sequence-specific DNA binding GO:0000979 8.96 H3-3B H3-3A
4 ubiquitin-like protein ligase binding GO:0044389 8.62 STAT2 JUN

Sources for Kunjin Encephalitis

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
19 FMA
28 GO
29 GTR
30 HMDB
31 HPO
32 ICD10
33 ICD10 via Orphanet
34 ICD9CM
35 IUPHAR
36 KEGG
37 LifeMap
39 LOVD
41 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
53 NINDS
54 Novoseek
56 OMIM
57 OMIM via Orphanet
61 PubMed
63 QIAGEN
68 SNOMED-CT via HPO
69 TGDB
70 Tocris
71 UMLS
72 UMLS via Orphanet
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