KFD
MCID: KYS001
MIFTS: 30

Kyasanur Forest Disease (KFD)

Categories: Genetic diseases, Infectious diseases, Rare diseases

Aliases & Classifications for Kyasanur Forest Disease

MalaCards integrated aliases for Kyasanur Forest Disease:

Name: Kyasanur Forest Disease 12 76 53 59 3 44 15 73
Kfd 53 3
Kyasanur Hemorrhagic Fever 59
Monkey Diseases 73
Monkey Disease 59
Monkey Fever 59
Kfd Virus 53

Classifications:

Orphanet: 59  
Rare infectious diseases


External Ids:

Disease Ontology 12 DOID:11320
ICD10 33 A98.2
ICD9CM 35 065.2
MeSH 44 D007733
SNOMED-CT 68 23097003
Orphanet 59 ORPHA319254
UMLS via Orphanet 74 C0022810
ICD10 via Orphanet 34 A98.2

Summaries for Kyasanur Forest Disease

Disease Ontology : 12 A viral infectious disease that is a hemorrhagic fever, has material basis in Kyasanur forest disease virus, which is transmitted by Haemaphysalis spinigera tick bite. The infection has symptom fever, has symptom headache, has symptom stiffness of the neck, has symptom severe muscle pain, has symptom cough, has symptom dehydration, and has symptom bleeding problems.

MalaCards based summary : Kyasanur Forest Disease, also known as kfd, is related to viral infectious disease and marburg hemorrhagic fever. An important gene associated with Kyasanur Forest Disease is ALK (ALK Receptor Tyrosine Kinase), and among its related pathways/superpathways is Pathways in cancer. Affiliated tissues include testes, brain and endothelial, and related phenotypes are Decreased shRNA abundance (Z-score < -2) and Decreased shRNA abundance (Z-score < -2)

CDC : 3 Kyasanur Forest disease (KFD) is caused by Kyasanur Forest disease virus (KFDV), a member of the virus family Flaviviridae. KFDV was identified in 1957 when it was isolated from a sick monkey from the Kyasanur Forest in Karnataka (formerly Mysore) State, India. Since then, between 400-500 humans cases per year have been reported.

Wikipedia : 76 Kyasanur Forest disease (KFD) is a tick-borne viral hemorrhagic fever endemic to South Asia. The disease... more...

Related Diseases for Kyasanur Forest Disease

Diseases related to Kyasanur Forest Disease via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 13)
# Related Disease Score Top Affiliating Genes
1 viral infectious disease 30.4 ERVW-1 IFNA1
2 marburg hemorrhagic fever 11.5
3 encephalitis 10.5
4 tick-borne encephalitis 10.4
5 hemorrhagic fever 10.4
6 chikungunya 10.2
7 alkhurma hemorrhagic fever 10.2
8 murray valley encephalitis 9.8 ERVW-1 IFNA1
9 human immunodeficiency virus infectious disease 9.8 ERVW-1 IFNA1
10 vaccinia 9.8 ERVW-1 IFNA1
11 noonan syndrome 1 9.8 ERVW-1 IFNA1
12 multiple sclerosis 9.7 ERVW-1 IFNA1
13 microcephaly 9.5

Graphical network of the top 20 diseases related to Kyasanur Forest Disease:



Diseases related to Kyasanur Forest Disease

Symptoms & Phenotypes for Kyasanur Forest Disease

GenomeRNAi Phenotypes related to Kyasanur Forest Disease according to GeneCards Suite gene sharing:

26
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Decreased shRNA abundance (Z-score < -2) GR00366-A-104 9.32 ERVW-1
2 Decreased shRNA abundance (Z-score < -2) GR00366-A-139 9.32 IFNA1
3 Decreased shRNA abundance (Z-score < -2) GR00366-A-14 9.32 IFNA1
4 Decreased shRNA abundance (Z-score < -2) GR00366-A-145 9.32 IFNA1
5 Decreased shRNA abundance (Z-score < -2) GR00366-A-175 9.32 IFNA1
6 Decreased shRNA abundance (Z-score < -2) GR00366-A-209 9.32 IFNA1
7 Decreased shRNA abundance (Z-score < -2) GR00366-A-34 9.32 ERVW-1 IFNA1
8 Decreased shRNA abundance (Z-score < -2) GR00366-A-61 9.32 IFNA1
9 Decreased shRNA abundance (Z-score < -2) GR00366-A-68 9.32 ERVW-1

Drugs & Therapeutics for Kyasanur Forest Disease

Search Clinical Trials , NIH Clinical Center for Kyasanur Forest Disease

Cochrane evidence based reviews: kyasanur forest disease

Genetic Tests for Kyasanur Forest Disease

Anatomical Context for Kyasanur Forest Disease

MalaCards organs/tissues related to Kyasanur Forest Disease:

41
Testes, Brain, Endothelial, Lymph Node

Publications for Kyasanur Forest Disease

Articles related to Kyasanur Forest Disease:

(show top 50) (show all 145)
# Title Authors Year
1
Prevalence and spatial distribution of Ixodid tick populations in the forest fringes of Western Ghats reported with human cases of Kyasanur forest disease and monkey deaths in South India. ( 29594846 )
2018
2
Development of single step RT-PCR for detection of Kyasanur forest disease virus from clinical samples. ( 29560461 )
2018
3
Bioinformatics characterization of envelope glycoprotein from Kyasanur Forest disease virus. ( 29806609 )
2018
4
Comparative genome analysis of Alkhumra hemorrhagic fever virus with Kyasanur forest disease and tick-borne encephalitis viruses by the in silico approach. ( 29745301 )
2018
5
Epidemiology, Pathogenesis, and Control of a Tick-Borne Disease- Kyasanur Forest Disease: Current Status and Future Directions. ( 29868505 )
2018
6
Kyasanur Forest Disease Prevalence in Western Ghats Proven and Confirmed by Recent Outbreak in Maharashtra, India, 2016. ( 29336707 )
2018
7
Kyasanur Forest Disease Classification Framework Using Novel Extremal Optimization Tuned Neural Network in Fog Computing Environment. ( 30173290 )
2018
8
Clinical & epidemiological significance of Kyasanur forest disease. ( 30381537 )
2018
9
Kyasanur Forest disease virus infection activates human vascular endothelial cells and monocyte-derived dendritic cells. ( 30401896 )
2018
10
Preliminary risk maps for transmission of kyasanur forest disease in Southern India. ( 28218163 )
2017
11
Occupational exposure of cashew nut workers to Kyasanur Forest disease in Goa, India. ( 28627428 )
2017
12
An outbreak of Kyasanur forest disease in the Wayanad and Malappuram districts of Kerala, India. ( 27692988 )
2017
13
Kyasanur forest disease: Another flavivirus requiring more research? Results of a bibliometric assessment. ( 28843350 )
2017
14
Kyasanur forest disease virus breaking the endemic barrier: AnA investigation into ecological effects on disease emergence and future outlook. ( 28220635 )
2017
15
Development of a subgenomic clone system for Kyasanur Forest disease virus. ( 27357207 )
2016
16
Kyasanur Forest Disease - First Reported Case in Kerala. ( 27731570 )
2016
17
Kyasanur Forest Disease (KFD): Rare Disease of Zoonotic Origin. ( 28327690 )
2016
18
Outbreak of Kyasanur Forest disease (monkey fever) in Sindhudurg, Maharashtra State, India, 2016. ( 26997635 )
2016
19
An Early Passage Human Isolate of Kyasanur Forest Disease Virus Shows Acute Neuropathology in Experimentally Infected CD-1 Mice. ( 27171207 )
2016
20
Difference in vector ticks dropping rhythm governs the epidemiology of Crimean-Congo haemorrhagic fever &amp;amp; Kyasanur forest disease in India. ( 28256476 )
2016
21
Limited Effects of Type I Interferons on Kyasanur Forest Disease Virus in Cell Culture. ( 27479197 )
2016
22
Kyasanur Forest disease outbreak and vaccination strategy,Shimoga District, India, 2013-2014. ( 25531141 )
2015
23
On the transmission pattern of Kyasanur Forest disease (KFD) in India. ( 26286631 )
2015
24
New focus of Kyasanur Forest disease virus activity in a tribal area in Kerala, India, 2014. ( 25750730 )
2015
25
Comparative pathogenesis of Alkhumra hemorrhagic fever and Kyasanur forest disease viruses in a mouse model. ( 24922308 )
2014
26
Outbreak of Kyasanur Forest disease in Thirthahalli, Karnataka, India, 2014. ( 25063021 )
2014
27
Kyasanur Forest disease virus infection in mice is associated with higher morbidity and mortality than infection with the closely related Alkhurma hemorrhagic fever virus. ( 24950196 )
2014
28
Expediency of dengue illness classification: the Sri Lankan perspective Highly infectious tick-borne viral diseases: Kyasanur forest disease and Crimean-Congo haemorrhagic fever in India. ( 28607249 )
2014
29
Coverage and effectiveness of Kyasanur forest disease (KFD) vaccine in Karnataka, South India, 2005-10. ( 23359421 )
2013
30
Spread of Kyasanur Forest disease, Bandipur Tiger Reserve, India, 2012-2013. ( 23977946 )
2013
31
Kyasanur Forest disease, India, 2011-2012. ( 23343570 )
2013
32
Kikuchi-Fujimoto disease in fine-needle aspiration smears: a clinico-cytologic study of 76 cases of KFD and 684 cases of reactive hyperplasia of the lymph node. ( 21953815 )
2013
33
Kikuchi Fujimoto disease (KFD) in a 31-year-old woman. ( 24303519 )
2013
34
The generation of a reverse genetics system for Kyasanur Forest Disease Virus and the ability to antagonize the induction of the antiviral state in vitro. ( 22100401 )
2012
35
Kyasanur forest disease virus: viremia and challenge studies in monkeys with evidence of cross-protection by Langat virus infection. ( 24627765 )
2012
36
Diagnosis of Kyasanur forest disease by nested RT-PCR, real-time RT-PCR and IgM capture ELISA. ( 22874757 )
2012
37
Kyasanur forest disease. ( 23110991 )
2012
38
Kyasanur Forest Disease virus Alkhurma subtype in ticks, Najran Province, Saudi Arabia. ( 21529425 )
2011
39
Recent ancestry of Kyasanur Forest disease virus. ( 19788811 )
2009
40
Isolation of kyasanur forest disease virus from febrile patient, yunnan, china. ( 19193286 )
2009
41
Kyasanur forest disease: an epidemiological view in India. ( 16710839 )
2006
42
Field evaluation of formalin inactivated Kyasanur forest disease virus tissue culture vaccine in three districts of Karnataka state. ( 7927566 )
1994
43
Analysis of the structural protein gene sequence shows Kyasanur Forest disease virus as a distinct member in the tick-borne encephalitis virus serocomplex. ( 8113732 )
1994
44
Clinical study of 100 cases of Kyasanur Forest disease with clinicopathological correlation. ( 8225455 )
1993
45
Circulating interferon-alpha in patients with Kyasanur forest disease. ( 1959947 )
1991
46
Clinical, clinicopathologic, and hematologic features of Kyasanur Forest disease. ( 2665018 )
1989
47
The epizootics of Kyasanur Forest disease in wild monkeys during 1964 to 1973. ( 3603621 )
1986
48
Spatial distribution of infected Haemaphysalis nymphs in the epizootic localities of Kyasanur forest disease. ( 6668008 )
1983
49
Ocular manifestations of Kyasanur forest disease (a clinical study). ( 6671795 )
1983
50
Ocular changes in Kyasanur forest disease. ( 6674351 )
1983

Variations for Kyasanur Forest Disease

Expression for Kyasanur Forest Disease

Search GEO for disease gene expression data for Kyasanur Forest Disease.

Pathways for Kyasanur Forest Disease

Pathways related to Kyasanur Forest Disease according to GeneCards Suite gene sharing:

# Super pathways Score Top Affiliating Genes
1 11.34 ALK IFNA1

GO Terms for Kyasanur Forest Disease

Sources for Kyasanur Forest Disease

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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