MCID: LCR009
MIFTS: 21

Lacrimal Gland Adenocarcinoma

Categories: Cancer diseases, Endocrine diseases, Eye diseases, Neuronal diseases

Aliases & Classifications for Lacrimal Gland Adenocarcinoma

MalaCards integrated aliases for Lacrimal Gland Adenocarcinoma:

Name: Lacrimal Gland Adenocarcinoma 12 15
Adenocarcinoma of Lacrimal Gland 12 74

Classifications:



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Disease Ontology 12 DOID:298
NCIt 51 C4541
UMLS 74 C0346341

Summaries for Lacrimal Gland Adenocarcinoma

Disease Ontology : 12 A lacrimal gland carcinoma that derives from epithelial cells of glandular origin.

MalaCards based summary : Lacrimal Gland Adenocarcinoma, also known as adenocarcinoma of lacrimal gland, is related to adenocarcinoma and alacrima, achalasia, and mental retardation syndrome. An important gene associated with Lacrimal Gland Adenocarcinoma is BPTF (Bromodomain PHD Finger Transcription Factor), and among its related pathways/superpathways are One carbon pool by folate and Pyruvate metabolism and Citric Acid (TCA) cycle. Affiliated tissues include eye, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Lacrimal Gland Adenocarcinoma

Diseases related to Lacrimal Gland Adenocarcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 adenocarcinoma 10.3
2 alacrima, achalasia, and mental retardation syndrome 9.7 BPTF NFIB
3 lacrimal system cancer 9.3 BPTF NFIB PSPH SHMT1
4 lacrimal gland carcinoma 9.2 BPTF NFIB PSPH SHMT1

Symptoms & Phenotypes for Lacrimal Gland Adenocarcinoma

GenomeRNAi Phenotypes related to Lacrimal Gland Adenocarcinoma according to GeneCards Suite gene sharing:

27 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.47 NFIB
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.47 NFIB
3 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.47 BPTF
4 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.47 BPTF
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.47 NFIB
6 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.47 BPTF
7 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.47 BPTF
8 Increased shRNA abundance (Z-score > 2) GR00366-A-202 9.47 BPTF
9 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.47 NFIB
10 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.47 BPTF NFIB
11 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.47 BPTF
12 Increased shRNA abundance (Z-score > 2) GR00366-A-4 9.47 BPTF
13 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.47 BPTF

Drugs & Therapeutics for Lacrimal Gland Adenocarcinoma

Search Clinical Trials , NIH Clinical Center for Lacrimal Gland Adenocarcinoma

Genetic Tests for Lacrimal Gland Adenocarcinoma

Anatomical Context for Lacrimal Gland Adenocarcinoma

MalaCards organs/tissues related to Lacrimal Gland Adenocarcinoma:

42
Eye

Publications for Lacrimal Gland Adenocarcinoma

Articles related to Lacrimal Gland Adenocarcinoma:

(show all 11)
# Title Authors Year
1
Primary poorly differentiated lacrimal gland adenocarcinoma in left ocular region: A rare case report. ( 30212949 )
2018
2
Lacrimal gland adenocarcinoma responding to checkpoint inhibition and androgen deprivation. ( 30159157 )
2018
3
Surgical excision of a feline orbital lacrimal gland adenocarcinoma with adjunctive cryotherapy and carboplatin-impregnated bead implantation. ( 28799265 )
2018
4
Primary ductal adenocarcinoma of lacrimal gland: Two case reports and review of the literature. ( 29675349 )
2018
5
A benign presentation of primary ductal adenocarcinoma of lacrimal gland: A rare malignancy. ( 26669339 )
2015
6
Clinicopathologic and immunohistochemical features of primary ductal adenocarcinoma of lacrimal gland: five new cases and review of literature. ( 23613093 )
2013
7
Primary lacrimal gland adenocarcinoma of the third eyelid in a horse. ( 21199279 )
2011
8
Basal cell adenocarcinoma of lacrimal gland. ( 22132848 )
2011
9
Orbital adenocarcinoma of lacrimal gland origin in a dog. ( 11289213 )
2001
10
Adenocarcinoma of lacrimal gland. ( 8035974 )
1994
11
Adenocarcinoma of lacrimal gland. ( 20256346 )
1947

Variations for Lacrimal Gland Adenocarcinoma

Expression for Lacrimal Gland Adenocarcinoma

Search GEO for disease gene expression data for Lacrimal Gland Adenocarcinoma.

Pathways for Lacrimal Gland Adenocarcinoma

GO Terms for Lacrimal Gland Adenocarcinoma

Biological processes related to Lacrimal Gland Adenocarcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 L-serine metabolic process GO:0006563 8.62 PSPH SHMT1

Sources for Lacrimal Gland Adenocarcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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