MCID: LCR011
MIFTS: 28

Lacrimal Gland Carcinoma

Categories: Cancer diseases, Endocrine diseases, Neuronal diseases
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Aliases & Classifications for Lacrimal Gland Carcinoma

MalaCards integrated aliases for Lacrimal Gland Carcinoma:

Name: Lacrimal Gland Carcinoma 11 14 71
Lacrimal Gland Cancer 11 14
Malignant Neoplasm of Lacrimal Gland 11
Malignant Tumour of Lacrimal Gland 11
Malignant Tumor of Lacrimal Gland 71
Carcinoma of the Lacrimal Gland 11
Tumor of the Lacrimal Gland 11
Neoplasm of Lacrimal Gland 11

Classifications:



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Disease Ontology 11 DOID:293 DOID:294
ICD9CM 34 190.2
SNOMED-CT 68 127004000 188271007
UMLS 71 C0153627 C0339124 C1334358

Summaries for Lacrimal Gland Carcinoma

MalaCards based summary: Lacrimal Gland Carcinoma, also known as lacrimal gland cancer, is related to mixed lacrimal gland cancer and myoepithelial carcinoma. An important gene associated with Lacrimal Gland Carcinoma is RPL39L (Ribosomal Protein L39 Like), and among its related pathways/superpathways are One-carbon metabolism and related pathways and serine and glycine biosynthesis. Affiliated tissues include eye, salivary gland and lymph node.

Related Diseases for Lacrimal Gland Carcinoma

Diseases related to Lacrimal Gland Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 130)
# Related Disease Score Top Affiliating Genes
1 mixed lacrimal gland cancer 31.9 PIP KRT7
2 myoepithelial carcinoma 30.5 NFIB KRT7
3 sebaceous adenocarcinoma 30.3 PIP KRT7
4 epithelial-myoepithelial carcinoma 30.1 PIP NFIB KRT7
5 acinar cell carcinoma 30.1 NFIB KRT7
6 signet ring cell adenocarcinoma 30.0 PIP KRT7
7 eyelid carcinoma 30.0 PIP KRT7
8 breast lobular carcinoma 29.7 PIP KRT7
9 breast secretory carcinoma 29.6 PIP NFIB KRT7
10 salivary gland adenoid cystic carcinoma 29.6 PIP NFIB KRT7
11 lacrimal gland adenocarcinoma 29.4 SHMT1 RPL39L RPL39 PSPH NFIB LYPD5
12 lacrimal gland adenoid cystic carcinoma 27.8 SHMT1 RPL39L RPL39 PSPH NFIB LYPD5
13 lacrimal gland mucoepidermoid carcinoma 11.4
14 lacrimal gland squamous cell carcinoma 11.4
15 mucoepidermoid carcinoma 10.6
16 rare tumor 10.5
17 adenoid cystic carcinoma 10.4
18 ptosis 10.3
19 orbital cancer 10.2
20 large cell carcinoma 10.2
21 lymphoepithelioma-like carcinoma 10.2
22 rhabdoid tumor predisposition syndrome 1 10.2
23 rhabdoid cancer 10.2
24 amyloid tumor 10.2
25 pleomorphic adenoma carcinoma 10.2
26 pleomorphic adenoma 10.2
27 adenoma 10.2
28 dry eye syndrome 10.1
29 breast cancer 10.1
30 oncocytoma 10.1
31 gastric cancer 10.1
32 tatton-brown-rahman syndrome 10.1
33 benign teratoma 10.1
34 diffuse gastric cancer 10.1
35 keratoconus 10.1
36 open-angle glaucoma 10.1
37 sarcoma 10.1
38 squamous cell carcinoma 10.1
39 neuroendocrine carcinoma 10.1
40 optic nerve disease 10.1
41 leiomyosarcoma 10.1
42 keratopathy 10.1
43 hemangioma 10.1
44 papilloma 10.1
45 adenocarcinoma 10.1
46 merkel cell carcinoma 10.1
47 cavernous hemangioma 10.1
48 adenosquamous carcinoma 10.1
49 dermoid cyst of ovary 10.1
50 conjunctivitis 10.1

Graphical network of the top 20 diseases related to Lacrimal Gland Carcinoma:



Diseases related to Lacrimal Gland Carcinoma

Symptoms & Phenotypes for Lacrimal Gland Carcinoma

Drugs & Therapeutics for Lacrimal Gland Carcinoma

Search Clinical Trials, NIH Clinical Center for Lacrimal Gland Carcinoma

Genetic Tests for Lacrimal Gland Carcinoma

Anatomical Context for Lacrimal Gland Carcinoma

Organs/tissues related to Lacrimal Gland Carcinoma:

MalaCards : Eye, Salivary Gland, Lymph Node, Liver, Bone, Kidney

Publications for Lacrimal Gland Carcinoma

Articles related to Lacrimal Gland Carcinoma:

(show top 50) (show all 265)
# Title Authors PMID Year
1
Risk and Lag-time for Development of Lacrimal Gland Carcinoma Expleomorphic Adenoma: Observations and Conjectural Study. 62
35550483 2022
2
Visual outcome and ocular complications in patients with lacrimal gland carcinoma after eye-sparing surgery and adjuvant radiation therapy. 62
36229179 2022
3
Stereotactic radiosurgery as a successful method to control meningeal metastatic adenoid cystic carcinoma of the lacrimal gland: A case report. 62
35949893 2022
4
Does Multimodal Treatment Improve Eye and Life Salvage in Adenoid Cystic Carcinoma of the Lacrimal Gland? 62
34873122 2022
5
Re: "Does Multimodal Treatment Improve Eye and Life Salvage in Adenoid Cystic Carcinoma of the Lacrimal Gland?" 62
35797665 2022
6
Reply Re: "Does Multimodal Treatment Improve Eye and Life Salvage in Adenoid Cystic Carcinoma of the Lacrimal Gland?" 62
35797666 2022
7
[Adenoid cystic carcinoma of the lacrimal gland: A case report]. 62
35090758 2022
8
Clinical and radiologic outcomes of pleomorphic adenoma and adenoid cystic carcinoma of the lacrimal gland. 62
35544926 2022
9
Genome Sequencing and Apoptotic Markers to Assess Treatment Response of Lacrimal Gland Adenoid Cystic Carcinoma to Intra-Arterial Cytoreductive Chemotherapy. 62
34798653 2022
10
Bevacizumab is an Efficient Therapeutic Approach with Low Side Effects in Patient-Derived Xenografts of Adenoid Cystic Carcinoma of the Lacrimal Gland. 62
35283648 2022
11
Mucoepidermoid carcinoma of the lacrimal gland in a patient with the CRTC1-MAML2 fusion gene. 62
34630791 2021
12
Carcinoma Expleomorphic Adenoma of the Lacrimal Gland. 62
33710040 2021
13
Prognostic factors for local recurrence and survival and impact of local treatments on survival in lacrimal gland carcinoma. 62
32680839 2021
14
Bioinformatics identification of the candidate microRNAs and construction of a competing endogenous RNA regulatory network in lacrimal gland adenoid cystic carcinoma high-grade transformation. 62
33747217 2021
15
Histopathologic Observations of Eyes in Exenterated Orbits After Neoadjuvant Intra-Arterial Cytoreductive Chemotherapy for Adenoid Cystic Carcinoma of the Lacrimal Gland. 62
32890114 2021
16
Retrospective Analysis of Clinicopathological Characteristics of Lacrimal Gland Pleomorphic Adenoma and Mechanism of Tumorigenesis by the Imbalance Between Apoptosis and Proliferation. 62
33737504 2021
17
High-risk human papillomavirus positive primary squamous cell carcinoma of the lacrimal gland: a case report. 62
31973618 2021
18
Epithelial-Myoepithelial Carcinoma of the Lacrimal Gland: Case Report of Youngest Patient. 62
32332692 2020
19
Malignant Mixed Tumor (Carcinoma Ex Pleomorphic Adenoma) of the Lacrimal Gland. 62
32282452 2020
20
Sclerosing Signet Ring Cell Carcinoma of the Lacrimal Gland: A Potentially New Primary Entity. 62
33005616 2020
21
Outcomes in patients with lacrimal gland carcinoma treated with definitive radiotherapy or eye-sparing surgery followed by adjuvant radiotherapy. 62
32571366 2020
22
Outcomes after eye-sparing surgery vs orbital exenteration in patients with lacrimal gland carcinoma. 62
32048377 2020
23
Primary ductal adenocarcinoma of the lacrimal gland: A review and report of five cases. 62
31837385 2020
24
[Does orbital exenteration still has a place in 2019?] 62
31831277 2020
25
Adenoid Cystic Carcinoma of the Lacrimal Gland: High Dose Adjuvant Proton Therapy to Improve Patients Outcomes. 62
32133287 2020
26
Mucoepidermoid Carcinoma of the Lacrimal Gland: A Case Report. 62
35531581 2020
27
Invasive Carcinoma Ex-Pleomorphic Adenoma of the Lacrimal Gland with a Cystadenocarcinoma Component: A Case Report and Review of the Literature. 62
32850170 2020
28
A Case of Lacrimal Gland Ductal Carcinoma With Regional Lymph Node Metastasis. 62
31365510 2019
29
Clinical Management of Acinic Cell Carcinoma of the Lacrimal Gland. 62
31762749 2019
30
Long-term Outcomes of Globe-Preserving Surgery with Proton Beam Radiation for Adenoid Cystic Carcinoma of the Lacrimal Gland. 62
30686477 2019
31
INI1/SMARCB1-Deficient Carcinoma (Rhabdoid Tumor) of the Lacrimal Gland. 62
30856630 2019
32
Fibroblast growth factor receptor 1 (FGFR1) as a therapeutic target in adenoid cystic carcinoma of the lacrimal gland. 62
30728899 2019
33
Cranio-orbital Resection Does Not Appear to Improve Survival of Patients With Lacrimal Gland Carcinoma. 62
30130333 2019
34
[Treatment Options for Adenoid Cystic Lacrimal Gland Carcinoma - A Case Series and Literature Review]. 62
30567007 2019
35
Long-term Outcomes of Globe-Preserving Surgery With Proton Beam Radiation for Adenoid Cystic Carcinoma of the Lacrimal Gland. 62
30071211 2018
36
Eye-Preserving Surgery Followed by Adjuvant Radiotherapy for Lacrimal Gland Carcinoma: Outcomes in 37 Patients. 62
29634603 2018
37
High-grade Mucoepidermoid Carcinoma of the Lacrimal Gland. 62
30311467 2018
38
Primary Secretory Carcinoma of the Lacrimal Gland: Report of a New Entity. 62
29963997 2018
39
Secretory Carcinoma of the Lacrimal Gland: A Rare Case Report. 62
30059394 2018
40
Primary poorly differentiated lacrimal gland adenocarcinoma in left ocular region: A rare case report. 62
30212949 2018
41
Overview of benign and malignant lacrimal gland tumors. 62
30028745 2018
42
Successful Treatment of Erlotinib on Metastatic Adenoid Cystic Carcinoma of the Lacrimal Gland. 62
29998897 2018
43
Corneal complications after orbital radiotherapy for primary epithelial malignancies of the lacrimal gland. 62
29051324 2018
44
Orbital exenteration: Institutional review of evolving trends in indications and rehabilitation techniques. 62
29039986 2018
45
Online proton therapy monitoring: clinical test of a Silicon-photodetector-based in-beam PET. 62
29511282 2018
46
Lacrimal myoepithelial carcinoma ex recurrent pleomorphic adenoma: A clinicopathological report and review of the literature. 62
29387416 2018
47
Diagnostic pitfall: primary myoepithelial carcinoma of the lacrimal gland, case report and literature review. 62
30123086 2018
48
Long-Term Outcomes of Eye-Sparing Surgery for Adenoid Cystic Carcinoma of Lacrimal Gland. 62
28221296 2018
49
Assessment of p16 expression and HPV infection in adenoid cystic carcinoma of the lacrimal gland. 62
29430168 2018
50
Adenoid cystic carcinoma of the lacrimal gland in a 14-year-old male. 62
28738175 2017

Variations for Lacrimal Gland Carcinoma

Expression for Lacrimal Gland Carcinoma

Search GEO for disease gene expression data for Lacrimal Gland Carcinoma.

Pathways for Lacrimal Gland Carcinoma

GO Terms for Lacrimal Gland Carcinoma

Biological processes related to Lacrimal Gland Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 L-serine metabolic process GO:0006563 8.92 SHMT1 PSPH

Sources for Lacrimal Gland Carcinoma

2 CDC
6 CNVD
8 Cosmic
9 dbSNP
10 DGIdb
16 EFO
17 ExPASy
18 FMA
19 GARD
27 GO
28 GTR
29 HMDB
30 HPO
31 ICD10
32 ICD10 via Orphanet
33 ICD11
34 ICD9CM
35 IUPHAR
36 LifeMap
38 LOVD
40 MedGen
43 MeSH
44 MESH via Orphanet
45 MGI
48 NCI
49 NCIt
50 NDF-RT
52 NINDS
53 Novoseek
55 ODiseA
56 OMIM via Orphanet
57 OMIM® (Updated 08-Dec-2022)
61 PubChem
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 Tocris
71 UMLS
72 UMLS via Orphanet
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