MCID: LCR011
MIFTS: 26

Lacrimal Gland Carcinoma

Categories: Neuronal diseases, Cancer diseases, Eye diseases, Endocrine diseases

Aliases & Classifications for Lacrimal Gland Carcinoma

MalaCards integrated aliases for Lacrimal Gland Carcinoma:

Name: Lacrimal Gland Carcinoma 12 15 73
Lacrimal Gland Cancer 12 15
Malignant Neoplasm of Lacrimal Gland 12
Malignant Tumour of Lacrimal Gland 12
Malignant Tumor of Lacrimal Gland 73
Carcinoma of the Lacrimal Gland 12
Tumor of the Lacrimal Gland 12
Neoplasm of Lacrimal Gland 12

Classifications:



External Ids:

Disease Ontology 12 DOID:293 DOID:294
ICD9CM 35 190.2

Summaries for Lacrimal Gland Carcinoma

MalaCards based summary : Lacrimal Gland Carcinoma, also known as lacrimal gland cancer, is related to adenoid cystic carcinoma and lacrimal gland adenocarcinoma. An important gene associated with Lacrimal Gland Carcinoma is RASSF1 (Ras Association Domain Family Member 1). Affiliated tissues include eye, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Lacrimal Gland Carcinoma

Diseases related to Lacrimal Gland Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show all 16)
# Related Disease Score Top Affiliating Genes
1 adenoid cystic carcinoma 29.9 NFIB RASSF1
2 lacrimal gland adenocarcinoma 29.5 BPTF NFIB PSPH
3 lacrimal gland mucoepidermoid carcinoma 11.5
4 lacrimal gland squamous cell carcinoma 11.2
5 mixed lacrimal gland cancer 11.1
6 adenoiditis 10.4
7 myoepithelioma 10.1
8 epithelial-myoepithelial carcinoma 10.1
9 pleomorphic adenoma carcinoma 9.9
10 pleomorphic adenoma 9.9
11 adenoma 9.9
12 leukemia, chronic lymphocytic 2 9.8
13 leukemia, chronic lymphocytic 9.8
14 leukemia 9.8
15 leukemia, b-cell, chronic 9.8
16 lacrimal system cancer 7.4 BPTF NFIB PSPH TENM1 TENM3

Graphical network of the top 20 diseases related to Lacrimal Gland Carcinoma:



Diseases related to Lacrimal Gland Carcinoma

Symptoms & Phenotypes for Lacrimal Gland Carcinoma

GenomeRNAi Phenotypes related to Lacrimal Gland Carcinoma according to GeneCards Suite gene sharing:

26 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.47 NFIB
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.47 NFIB
3 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.47 BPTF
4 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.47 BPTF
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.47 NFIB
6 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.47 BPTF
7 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.47 BPTF
8 Increased shRNA abundance (Z-score > 2) GR00366-A-202 9.47 BPTF
9 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.47 NFIB
10 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.47 BPTF NFIB
11 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.47 BPTF
12 Increased shRNA abundance (Z-score > 2) GR00366-A-4 9.47 BPTF
13 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.47 BPTF

Drugs & Therapeutics for Lacrimal Gland Carcinoma

Search Clinical Trials , NIH Clinical Center for Lacrimal Gland Carcinoma

Genetic Tests for Lacrimal Gland Carcinoma

Anatomical Context for Lacrimal Gland Carcinoma

MalaCards organs/tissues related to Lacrimal Gland Carcinoma:

41
Eye

Publications for Lacrimal Gland Carcinoma

Articles related to Lacrimal Gland Carcinoma:

(show all 11)
# Title Authors Year
1
Eye-Preserving Surgery Followed by Adjuvant Radiotherapy for Lacrimal Gland Carcinoma: Outcomes in 37 Patients. ( 29634603 )
2018
2
Eye-sparing multidisciplinary approach for the management of lacrimal gland carcinoma. ( 27027275 )
2016
3
Current treatment of lacrimal gland carcinoma. ( 27273588 )
2016
4
Management of Lacrimal Gland Carcinoma: Lessons From the Literature in the Past 40 Years. ( 26291539 )
2016
5
Expression profile of tumor suppressor gene RASSF1 in lacrimal gland carcinoma. ( 26125908 )
2015
6
Metastatic, her-2 amplified lacrimal gland carcinoma with response to lapatinib treatment. ( 25722902 )
2015
7
Postoperative radiotherapy with volumetric modulated arc therapy of lacrimal gland carcinoma: two case reports and literature review. ( 25471025 )
2014
8
Lacrimal gland carcinoma ex pleomorphic adenoma with chronic lymphocytic leukemia infiltration. ( 25336906 )
2014
9
Case of lacrimal gland carcinoma ex adenoma. ( 15060804 )
2004
10
Surface coil MR evaluation of a lacrimal gland carcinoma. ( 2844863 )
1988
11
Lacrimal gland carcinoma. ( 6294490 )
1982

Variations for Lacrimal Gland Carcinoma

Expression for Lacrimal Gland Carcinoma

Search GEO for disease gene expression data for Lacrimal Gland Carcinoma.

Pathways for Lacrimal Gland Carcinoma

GO Terms for Lacrimal Gland Carcinoma

Cellular components related to Lacrimal Gland Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 8.92 BPTF PSPH TENM1 TENM3

Biological processes related to Lacrimal Gland Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell morphogenesis GO:0000902 9.16 TENM1 TENM3
2 neuron development GO:0048666 8.96 TENM1 TENM3
3 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 8.62 TENM1 TENM3

Molecular functions related to Lacrimal Gland Carcinoma according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 9.13 PSPH TENM1 TENM3
2 cell adhesion molecule binding GO:0050839 8.62 TENM1 TENM3

Sources for Lacrimal Gland Carcinoma

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
Content
Loading form....