Lacrimal Gland Mucoepidermoid Carcinoma disease: Malacards - Research Articles, Drugs, Genes, Clinical Trials

Aliases & Classifications for Lacrimal Gland Mucoepidermoid Carcinoma

MalaCards integrated aliases for Lacrimal Gland Mucoepidermoid Carcinoma:

Name: Lacrimal Gland Mucoepidermoid Carcinoma ¹¹ ¹⁴ ⁷¹

Mucoepidermoid Carcinoma of the Lacrimal Gland ¹¹

Classifications:

MalaCards categories:
Global: Cancer diseases
Anatomical: Neuronal diseases Oral diseases Gastrointestinal diseases Endocrine diseases

See all MalaCards categories (disease lists)

External Ids:

Disease Ontology ¹¹ DOID:4685

NCIt ⁴⁹ C6091

UMLS ⁷¹ C1334359

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Summaries for Lacrimal Gland Mucoepidermoid Carcinoma

MalaCards based summary: Lacrimal Gland Mucoepidermoid Carcinoma, also known as mucoepidermoid carcinoma of the lacrimal gland, is related to mucoepidermoid carcinoma and oncocytoma. An important gene associated with Lacrimal Gland Mucoepidermoid Carcinoma is CRTC1 (CREB Regulated Transcription Coactivator 1), and among its related pathways/superpathways is Binding and Uptake of Ligands by Scavenger Receptors.

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Related Diseases for Lacrimal Gland Mucoepidermoid Carcinoma

Diseases related to Lacrimal Gland Mucoepidermoid Carcinoma via text searches within MalaCards or GeneCards Suite gene sharing:

(show top 50) (show all 145)

#	Related Disease	Score	Top Affiliating Genes
1	mucoepidermoid carcinoma	31.0	MAML2 KRT7 CRTC1
2	oncocytoma	29.9	KRT7 KRT20
3	lacrimal gland carcinoma	10.7
4	rare tumor	10.2
5	bronchus mucoepidermoid carcinoma	10.2	MAML2 CRTC1
6	schneiderian carcinoma	10.2	MAML2 CRTC1
7	lipoadenoma	10.2	MAML2 CRTC1
8	esophageal adenoid cystic carcinoma	10.2	CRTC3 CRTC1
9	lacrimal system cancer	10.2	MAML2 CRTC1
10	cervical adenosquamous carcinoma	10.2	MAML2 CRTC1
11	human t-cell leukemia virus type 1	10.2	CRTC3 CRTC1
12	pancreatic adenosquamous carcinoma	10.1	MAML2 CRTC1
13	mammary analogue secretory carcinoma	10.1	MAML2 CRTC1
14	aggressive digital papillary adenocarcinoma	10.1	MAML2 KRT7
15	malignant acrospiroma	10.1	MAML2 KRT7
16	breast secretory carcinoma	10.1	MAML2 KRT7
17	eccrine sweat gland cancer	10.1	MAML2 KRT7
18	bile duct signet ring cell carcinoma	10.1	KRT7 KRT20
19	urethral villous adenoma	10.1	KRT7 KRT20
20	endometrial transitional cell carcinoma	10.1	KRT7 KRT20
21	seminal vesicle adenocarcinoma	10.1	KRT7 KRT20
22	nephrogenic adenoma of urinary bladder	10.1	KRT7 KRT20
23	pancreatic serous cystadenocarcinoma	10.1	KRT7 KRT20
24	atrophic vulva	10.1	KRT7 KRT20
25	eccrine porocarcinoma	10.1	MAML2 KRT7
26	mucinous bronchioloalveolar adenocarcinoma	10.1	KRT7 KRT20
27	bladder benign neoplasm	10.1	KRT7 KRT20
28	vaginal tubulovillous adenoma	10.1	KRT7 KRT20
29	urinary bladder villous adenoma	10.1	KRT7 KRT20
30	anal canal adenocarcinoma	10.1	KRT7 KRT20
31	vulva adenocarcinoma	10.1	KRT7 KRT20
32	aortic malignant tumor	10.1	KRT7 KRT20
33	female urethral cancer	10.1	KRT7 KRT20
34	male urethral cancer	10.1	KRT7 KRT20
35	cystitis	10.1	KRT7 KRT20
36	cystitis cystica	10.0	KRT7 KRT20
37	vulvar apocrine adenocarcinoma	10.0	KRT7 KRT20
38	mucinous ovarian cystadenoma	10.0	KRT7 KRT20
39	cystadenoma	10.0	KRT7 KRT20
40	colonic lymphangioma	10.0	KRT7 KRT20
41	internal hemorrhoid	10.0	KRT7 KRT20
42	hemorrhoid	10.0	KRT7 KRT20
43	intratubular embryonal carcinoma	10.0	KRT7 KRT20
44	urinary bladder small cell neuroendocrine carcinoma	10.0	KRT7 KRT20
45	neuroendocrine carcinoma	10.0	KRT7 KRT20
46	bile duct cystadenocarcinoma	10.0	KRT7 KRT20
47	anal paget's disease	10.0	KRT7 KRT20
48	rectosigmoid junction neoplasm	10.0	KRT7 KRT20
49	sigmoid neoplasm	10.0	KRT7 KRT20
50	krukenberg carcinoma	10.0	KRT7 KRT20

Graphical network of the top 20 diseases related to Lacrimal Gland Mucoepidermoid Carcinoma:

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Symptoms & Phenotypes for Lacrimal Gland Mucoepidermoid Carcinoma

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Drugs & Therapeutics for Lacrimal Gland Mucoepidermoid Carcinoma

Search Clinical Trials, NIH Clinical Center for Lacrimal Gland Mucoepidermoid Carcinoma

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Genetic Tests for Lacrimal Gland Mucoepidermoid Carcinoma

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Anatomical Context for Lacrimal Gland Mucoepidermoid Carcinoma

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Publications for Lacrimal Gland Mucoepidermoid Carcinoma

Articles related to Lacrimal Gland Mucoepidermoid Carcinoma:

(show all 11)

#	Title	Authors	PMID	Year
1	Mucoepidermoid carcinoma of the lacrimal gland in a patient with the CRTC1-MAML2 fusion gene. ⁶²	Makino K...Ishii H	34630791	2021
2	Mucoepidermoid Carcinoma of the Lacrimal Gland: A Case Report. ⁶²	Alfin RJ...Ramyil AV	35531581	2020
3	High-grade Mucoepidermoid Carcinoma of the Lacrimal Gland. ⁶²	Hwang SJ...Kim KH	30311467	2018
4	Low-Grade Mucoepidermoid Carcinoma of the Lacrimal Gland in a Teenaged Patient. ⁶²	Gedar Totuk OM...Mestanoglu M	29318070	2017
5	CRTC1-MAML2 gene fusion in mucoepidermoid carcinoma of the lacrimal gland. ⁶²	Von Holstein SL...Stenman G	22323114	2012
6	Mucoepidermoid carcinoma of the lacrimal gland: 25 cases and a review and update of the literature. ⁶²	Eviatar JA...Hornblass A	8217958	1993
7	Mucoepidermoid carcinoma of the lacrimal gland. Report of a case with oncocytic features arising in a patient with chronic dacryops. ⁶²	Levin LA...Jakobiec FA	1961643	1991
8	Mucoepidermoid carcinoma of the lacrimal gland fossa: confirmation by ultrastructural study. ⁶²	Lawton AW...Karesh JW	2717990	1989
9	Mucoepidermoid carcinoma of the lacrimal gland. An oxyphilic variant. ⁶²	Pulitzer DR...Eckert ER	2444200	1987
10	Mucoepidermoid carcinoma of the lacrimal gland. Case report and review of the literature. ⁶²	Sofinski SJ...Wan WL	3154555	1986
11	Mucoepidermoid carcinoma of the lacrimal gland. ⁶²	Wagoner MD...Albert DM	7103323	1982

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Genes for Lacrimal Gland Mucoepidermoid Carcinoma

Genes related to Lacrimal Gland Mucoepidermoid Carcinoma (0 elite genes):

- Elite gene

- Cancer Census gene in COSMIC

#	Symbol	Description	Category	Score	Evidence
1	CRTC1	CREB Regulated Transcription Coactivator 1	Protein Coding	6.95	DISEASES inferred ¹⁴
2	MAML2	Mastermind Like Transcriptional Coactivator 2	Protein Coding	6.85	DISEASES inferred ¹⁴
3	CRTC3	CREB Regulated Transcription Coactivator 3	Protein Coding	5.19	DISEASES inferred ¹⁴
4	KRT20	Keratin 20	Protein Coding	3.82	DISEASES inferred ¹⁴
5	SAA1	Serum Amyloid A1	Protein Coding	3.79	DISEASES inferred ¹⁴
6	CALR	Calreticulin	Protein Coding	3.41	DISEASES inferred ¹⁴
7	KRT7	Keratin 7	Protein Coding	3.18	DISEASES inferred ¹⁴

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Variations for Lacrimal Gland Mucoepidermoid Carcinoma

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Expression for Lacrimal Gland Mucoepidermoid Carcinoma

Search GEO for disease gene expression data for Lacrimal Gland Mucoepidermoid Carcinoma.

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Pathways for Lacrimal Gland Mucoepidermoid Carcinoma

Pathways related to Lacrimal Gland Mucoepidermoid Carcinoma according to GeneCards Suite gene sharing:

#	Super pathways	Score	Top Affiliating Genes
1	Binding and Uptake of Ligands by Scavenger Receptors ⁶⁶ Show member pathways Scavenging by Class A Receptors ⁶⁶ Scavenging by Class B Receptors ⁶⁶ Scavenging by Class F Receptors ⁶⁶ Scavenging by Class H Receptors ⁶⁶ Scavenging of heme from plasma ⁶⁶	10.58	SAA1 CALR

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GO Terms for Lacrimal Gland Mucoepidermoid Carcinoma

Cellular components related to Lacrimal Gland Mucoepidermoid Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	endocytic vesicle lumen	GO:0071682	8.92	SAA1 CALR

Biological processes related to Lacrimal Gland Mucoepidermoid Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	energy homeostasis	GO:0097009	9.46	CRTC3 CRTC1
2	positive regulation of CREB transcription factor activity	GO:0032793	9.26	CRTC3 CRTC1
3	regulation of protein secretion	GO:0050708	8.92	SAA1 KRT20

Molecular functions related to Lacrimal Gland Mucoepidermoid Carcinoma according to GeneCards Suite gene sharing:

#	Name	GO ID	Score	Top Affiliating Genes
1	cAMP response element binding protein binding	GO:0008140	8.92	CRTC3 CRTC1

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Sources for Lacrimal Gland Mucoepidermoid Carcinoma

¹ BitterDB

² CDC

³ Cell Signaling Technology

⁴ ClinicalTrials

⁵ ClinVar

⁶ CNVD

⁷ Cochrane Library

⁸ Cosmic

⁹ dbSNP

¹⁰ DGIdb

¹¹ Disease Ontology

¹² diseasecard

¹³ DiseaseEnhancer

¹⁴ DISEASES

¹⁵ DrugBank

¹⁶ EFO

¹⁷ ExPASy

¹⁸ FMA

¹⁹ GARD

²⁰ GeneAnalytics

²¹ GeneCards

²² GeneGo (Thomson Reuters)

²³ GeneHancer via GeneCards

²⁴ GeneReviews

²⁵ GenomeRNAi

²⁶ GEO DataSets

²⁷ GO

²⁸ GTR

²⁹ HMDB

³⁰ HPO

³¹ ICD10

³² ICD10 via Orphanet

³³ ICD11

³⁴ ICD9CM

³⁵ IUPHAR

³⁶ LifeMap

³⁷ LncRNADisease

³⁸ LOVD

³⁹ MalaCards

⁴⁰ MedGen

⁴¹ MedlinePlus

⁴² MedlinePlus Genetics

⁴³ MeSH

⁴⁴ MESH via Orphanet

⁴⁵ MGI

⁴⁶ miR2Disease

⁴⁷ NCBI Bookshelf

⁴⁸ NCI

⁴⁹ NCIt

⁵⁰ NDF-RT

⁵¹ NIH Clinical Center

⁵² NINDS

⁵³ Novoseek

⁵⁴ Novus Biologicals

⁵⁵ ODiseA

⁵⁶ OMIM via Orphanet

⁵⁷ OMIM® (Updated 08-Dec-2022)

⁵⁸ Orphanet

⁵⁹ PathCards

⁶⁰ PharmGKB

⁶¹ PubChem

⁶² PubMed

⁶³ PubMed Health

⁶⁴ QIAGEN

⁶⁵ R&D Systems

⁶⁶ Reactome

⁶⁷ Sino Biological

⁶⁸ SNOMED-CT

⁶⁹ SNOMED-CT via HPO

⁷⁰ Tocris

⁷¹ UMLS

⁷² UMLS via Orphanet

⁷³ UniProtKB/Swiss-Prot

⁷⁴ WikiPathways

⁷⁵ Wikipedia

MCID: LCR002 MIFTS: 21	Lacrimal Gland Mucoepidermoid Carcinoma Categories: Cancer diseases, Endocrine diseases, Gastrointestinal diseases, Neuronal diseases, Oral diseases	Data Licensing For inquiries, contact: [email protected]
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