MCID: LCR012
MIFTS: 17

Lacrimal System Cancer

Categories: Neuronal diseases, Cancer diseases, Eye diseases

Aliases & Classifications for Lacrimal System Cancer

MalaCards integrated aliases for Lacrimal System Cancer:

Name: Lacrimal System Cancer 12 15
Neoplasm of Lacrimal System 12 73
Tumor of the Lacrimal System 12
Lacrimal System Neoplasm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:292
NCIt 50 C5102
SNOMED-CT 68 416510003
UMLS 73 C1334361

Summaries for Lacrimal System Cancer

MalaCards based summary : Lacrimal System Cancer, also known as neoplasm of lacrimal system, is related to lacrimal gland adenocarcinoma and lacrimal gland carcinoma. An important gene associated with Lacrimal System Cancer is NFIB (Nuclear Factor I B). Affiliated tissues include eye, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Lacrimal System Cancer

Diseases related to Lacrimal System Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 lacrimal gland adenocarcinoma 8.7 BPTF NFIB PSPH
2 lacrimal gland carcinoma 7.5 BPTF NFIB PSPH TENM1 TENM3

Symptoms & Phenotypes for Lacrimal System Cancer

GenomeRNAi Phenotypes related to Lacrimal System Cancer according to GeneCards Suite gene sharing:

26 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.47 NFIB
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.47 NFIB
3 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.47 BPTF
4 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.47 BPTF
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.47 NFIB
6 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.47 BPTF
7 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.47 BPTF
8 Increased shRNA abundance (Z-score > 2) GR00366-A-202 9.47 BPTF
9 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.47 NFIB
10 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.47 BPTF NFIB
11 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.47 BPTF
12 Increased shRNA abundance (Z-score > 2) GR00366-A-4 9.47 BPTF
13 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.47 BPTF

Drugs & Therapeutics for Lacrimal System Cancer

Search Clinical Trials , NIH Clinical Center for Lacrimal System Cancer

Genetic Tests for Lacrimal System Cancer

Anatomical Context for Lacrimal System Cancer

MalaCards organs/tissues related to Lacrimal System Cancer:

41
Eye

Publications for Lacrimal System Cancer

Variations for Lacrimal System Cancer

Expression for Lacrimal System Cancer

Search GEO for disease gene expression data for Lacrimal System Cancer.

Pathways for Lacrimal System Cancer

GO Terms for Lacrimal System Cancer

Cellular components related to Lacrimal System Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 neuron projection GO:0043005 8.92 BPTF PSPH TENM1 TENM3

Biological processes related to Lacrimal System Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 cell morphogenesis GO:0000902 9.16 TENM1 TENM3
2 neuron development GO:0048666 8.96 TENM1 TENM3
3 heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules GO:0007157 8.62 TENM1 TENM3

Molecular functions related to Lacrimal System Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 protein homodimerization activity GO:0042803 9.13 PSPH TENM1 TENM3
2 cell adhesion molecule binding GO:0050839 8.62 TENM1 TENM3

Sources for Lacrimal System Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 ExPASy
19 FMA
28 GO
29 GTR
30 HGMD
31 HMDB
32 HPO
33 ICD10
34 ICD10 via Orphanet
35 ICD9CM
36 IUPHAR
37 KEGG
38 LifeMap
40 LOVD
42 MedGen
44 MeSH
45 MESH via Orphanet
46 MGI
49 NCI
50 NCIt
51 NDF-RT
54 NINDS
55 Novoseek
57 OMIM
58 OMIM via Orphanet
62 PubMed
64 QIAGEN
69 SNOMED-CT via HPO
70 SNOMED-CT via Orphanet
71 TGDB
72 Tocris
73 UMLS
74 UMLS via Orphanet
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