MCID: LCR012
MIFTS: 19

Lacrimal System Cancer

Categories: Cancer diseases, Eye diseases, Neuronal diseases

Aliases & Classifications for Lacrimal System Cancer

MalaCards integrated aliases for Lacrimal System Cancer:

Name: Lacrimal System Cancer 12 15
Neoplasm of Lacrimal System 12 74
Tumor of the Lacrimal System 12
Lacrimal System Neoplasm 12

Classifications:



External Ids:

Disease Ontology 12 DOID:292
NCIt 51 C5102
UMLS 74 C1334361

Summaries for Lacrimal System Cancer

MalaCards based summary : Lacrimal System Cancer, also known as neoplasm of lacrimal system, is related to polymorphous low-grade adenocarcinoma and tonsil cancer. An important gene associated with Lacrimal System Cancer is BPTF (Bromodomain PHD Finger Transcription Factor), and among its related pathways/superpathways are One carbon pool by folate and Glycine, serine and threonine metabolism. Affiliated tissues include eye, tonsil and salivary gland, and related phenotypes are Increased shRNA abundance (Z-score > 2) and Increased shRNA abundance (Z-score > 2)

Related Diseases for Lacrimal System Cancer

Diseases related to Lacrimal System Cancer via text searches within MalaCards or GeneCards Suite gene sharing:

# Related Disease Score Top Affiliating Genes
1 polymorphous low-grade adenocarcinoma 9.8 NFIB NTRK3
2 tonsil cancer 9.7 MAML2 NFIB
3 salivary gland disease 9.7 MAML2 NFIB
4 alacrima, achalasia, and mental retardation syndrome 9.7 BPTF NFIB
5 oropharynx cancer 9.7 MAML2 NFIB
6 adenoid cystic carcinoma 9.5 NFIB NTRK3
7 lacrimal gland adenocarcinoma 9.2 BPTF NFIB PSPH SHMT1
8 lacrimal gland carcinoma 8.9 BPTF MAML2 NFIB PSPH SHMT1

Graphical network of the top 20 diseases related to Lacrimal System Cancer:



Diseases related to Lacrimal System Cancer

Symptoms & Phenotypes for Lacrimal System Cancer

GenomeRNAi Phenotypes related to Lacrimal System Cancer according to GeneCards Suite gene sharing:

27 (show all 13)
# Description GenomeRNAi Source Accession Score Top Affiliating Genes
1 Increased shRNA abundance (Z-score > 2) GR00366-A-105 9.47 NFIB
2 Increased shRNA abundance (Z-score > 2) GR00366-A-115 9.47 NFIB
3 Increased shRNA abundance (Z-score > 2) GR00366-A-12 9.47 BPTF
4 Increased shRNA abundance (Z-score > 2) GR00366-A-168 9.47 BPTF
5 Increased shRNA abundance (Z-score > 2) GR00366-A-177 9.47 NFIB
6 Increased shRNA abundance (Z-score > 2) GR00366-A-185 9.47 BPTF
7 Increased shRNA abundance (Z-score > 2) GR00366-A-190 9.47 BPTF
8 Increased shRNA abundance (Z-score > 2) GR00366-A-202 9.47 BPTF
9 Increased shRNA abundance (Z-score > 2) GR00366-A-25 9.47 NFIB
10 Increased shRNA abundance (Z-score > 2) GR00366-A-35 9.47 BPTF NFIB
11 Increased shRNA abundance (Z-score > 2) GR00366-A-36 9.47 BPTF
12 Increased shRNA abundance (Z-score > 2) GR00366-A-4 9.47 BPTF
13 Increased shRNA abundance (Z-score > 2) GR00366-A-52 9.47 BPTF

Drugs & Therapeutics for Lacrimal System Cancer

Search Clinical Trials , NIH Clinical Center for Lacrimal System Cancer

Genetic Tests for Lacrimal System Cancer

Anatomical Context for Lacrimal System Cancer

MalaCards organs/tissues related to Lacrimal System Cancer:

42
Eye, Tonsil, Salivary Gland

Publications for Lacrimal System Cancer

Variations for Lacrimal System Cancer

Expression for Lacrimal System Cancer

Search GEO for disease gene expression data for Lacrimal System Cancer.

Pathways for Lacrimal System Cancer

GO Terms for Lacrimal System Cancer

Biological processes related to Lacrimal System Cancer according to GeneCards Suite gene sharing:

# Name GO ID Score Top Affiliating Genes
1 L-serine metabolic process GO:0006563 8.62 PSPH SHMT1

Sources for Lacrimal System Cancer

3 CDC
7 CNVD
9 Cosmic
10 dbSNP
11 DGIdb
17 EFO
18 ExPASy
20 FMA
29 GO
30 GTR
31 HGMD
32 HMDB
33 HPO
34 ICD10
35 ICD10 via Orphanet
36 ICD9CM
37 IUPHAR
38 KEGG
39 LifeMap
41 LOVD
43 MedGen
45 MeSH
46 MESH via Orphanet
47 MGI
50 NCI
51 NCIt
52 NDF-RT
55 NINDS
56 Novoseek
58 OMIM
59 OMIM via Orphanet
63 PubMed
65 QIAGEN
70 SNOMED-CT via HPO
71 SNOMED-CT via Orphanet
72 TGDB
73 Tocris
74 UMLS
75 UMLS via Orphanet
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